Rudolph L. Juliano - Publications

Affiliations: 
Pharmacology University of North Carolina, Chapel Hill, Chapel Hill, NC 
Area:
Virology Biology, Cell Biology, Pharmacology

51 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Kondow-McConaghy HM, Muthukrishnan N, Erazo-Oliveras A, Najjar K, Juliano RL, Pellois JP. Impact of the Endosomal Escape Activity of Cell-Penetrating Peptides on the Endocytic Pathway. Acs Chemical Biology. 15: 2355-2363. PMID 32786263 DOI: 10.1021/Acschembio.0C00319  0.392
2019 Allen J, Najjar K, Erazo-Oliveras A, Kondow-McConaghy HM, Brock DJ, Graham K, Hager EC, Marschall ALJ, Dübel S, Juliano RL, Pellois JP. Cytosolic delivery of macromolecules in live human cells using the combined endosomal escape activities of a small molecule and cell penetrating peptides. Acs Chemical Biology. PMID 31633910 DOI: 10.1021/Acschembio.9B00585  0.385
2019 Agramunt J, Pedroso E, Kreda SM, Juliano RL, Grandas A. Retro-1-Oligonucleotide Conjugates. Synthesis and Biological Evaluation. Molecules (Basel, Switzerland). 24. PMID 30736307 DOI: 10.3390/Molecules24030579  0.302
2018 Juliano RL, Wang L, Tavares F, Brown EG, James L, Ariyarathna Y, Ming X, Mao C, Suto M. Structure-activity relationships and cellular mechanism of action of small molecules that enhance the delivery of oligonucleotides. Nucleic Acids Research. PMID 29361039 DOI: 10.1093/Nar/Gkx1320  0.357
2017 Wang L, Ariyarathna Y, Ming X, Yang B, James LI, Kreda SM, Porter M, Janzen W, Juliano RL. A Novel Family of Small Molecules that Enhance the Intracellular Delivery and Pharmacological Effectiveness of Antisense and Splice Switching Oligonucleotides. Acs Chemical Biology. PMID 28703575 DOI: 10.1021/Acschembio.7B00242  0.343
2016 Juliano RL. The delivery of therapeutic oligonucleotides. Nucleic Acids Research. PMID 27084936 DOI: 10.1093/Nar/Gkw236  0.39
2015 Juliano RL, Carver K. Cellular uptake and intracellular trafficking of oligonucleotides. Advanced Drug Delivery Reviews. 87: 35-45. PMID 25881722 DOI: 10.1016/J.Addr.2015.04.005  0.382
2014 Carver K, Ming X, Juliano RL. Multicellular tumor spheroids as a model for assessing delivery of oligonucleotides in three dimensions. Molecular Therapy. Nucleic Acids. 3: e153. PMID 24618852 DOI: 10.1038/Mtna.2014.5  0.354
2013 Ming X, Carver K, Michael Fisher, Romain Noel, Cintrat JC, Gillet D, Barbier J, Cao C, Bauman J, Juliano RL. The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides Nucleic Acids Research. 41: 3673-3687. PMID 23396438 DOI: 10.1093/Nar/Gkt066  0.365
2012 Kotula JW, Pratico ED, Ming X, Nakagawa O, Juliano RL, Sullenger BA. Aptamer-mediated delivery of splice-switching oligonucleotides to the nuclei of cancer cells. Nucleic Acid Therapeutics. 22: 187-95. PMID 22703281 DOI: 10.1089/Nat.2012.0347  0.373
2012 Juliano RL, Ming X, Nakagawa O. The chemistry and biology of oligonucleotide conjugates. Accounts of Chemical Research. 45: 1067-76. PMID 22353142 DOI: 10.1021/Ar2002123  0.421
2012 Juliano RL, Ming X, Nakagawa O. Cellular uptake and intracellular trafficking of antisense and siRNA oligonucleotides. Bioconjugate Chemistry. 23: 147-57. PMID 21992697 DOI: 10.1021/Bc200377D  0.39
2011 Cline LL, Janout V, Fisher M, Juliano RL, Regen SL. A molecular umbrella approach to the intracellular delivery of small interfering RNA Bioconjugate Chemistry. 22: 2210-2216. PMID 21985221 DOI: 10.1021/Bc200347X  0.369
2011 Frye S, Crosby M, Edwards T, Juliano R. US academic drug discovery Nature Reviews Drug Discovery. 10: 409-410. PMID 21629285 DOI: 10.1038/Nrd3462  0.324
2011 Ming X, Sato K, Juliano RL. Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes. Journal of Controlled Release : Official Journal of the Controlled Release Society. 153: 83-92. PMID 21571016 DOI: 10.1016/J.Jconrel.2011.04.029  0.416
2011 Xu R, Fisher M, Juliano RL. Targeted albumin-based nanoparticles for delivery of amphipathic drugs. Bioconjugate Chemistry. 22: 870-8. PMID 21452893 DOI: 10.1021/Bc1002295  0.368
2010 Nakagawa O, Ming X, Huang L, Juliano RL. Targeted intracellular delivery of antisense oligonucleotides via conjugation with small-molecule ligands. Journal of the American Chemical Society. 132: 8848-9. PMID 20550198 DOI: 10.1021/Ja102635C  0.374
2010 Alam MR, Ming X, Dixit V, Fisher M, Chen X, Juliano RL. The biological effect of an antisense oligonucleotide depends on its route of endocytosis and trafficking. Oligonucleotides. 20: 103-9. PMID 20038250 DOI: 10.1089/Oli.2009.0211  0.392
2009 Juliano RL, Alam R, Dixit V, Kang HM. Cell-targeting and cell-penetrating peptides for delivery of therapeutic and imaging agents. Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. 1: 324-35. PMID 20049800 DOI: 10.1002/Wnan.4  0.378
2008 Dixit V, Juliano RL. Selective killing of Smad4-negative tumor cells via a designed repressor strategy. Molecular Pharmacology. 74: 289-97. PMID 18426856 DOI: 10.1124/Mol.108.046953  0.306
2008 Healy KD, Hodgson L, Kim TY, Shutes A, Maddileti S, Juliano RL, Hahn KM, Harden TK, Bang YJ, Der CJ. DLC-1 suppresses non-small cell lung cancer growth and invasion by RhoGAP-dependent and independent mechanisms. Molecular Carcinogenesis. 47: 326-37. PMID 17932950 DOI: 10.1002/Mc.20389  0.324
2007 Nauwelaerts K, Fisher M, Froeyen M, Lescrinier E, Aerschot AV, Xu D, DeLong R, Kang H, Juliano RL, Herdewijn P. Structural characterization and biological evaluation of small interfering RNAs containing cyclohexenyl nucleosides. Journal of the American Chemical Society. 129: 9340-8. PMID 17616127 DOI: 10.1021/Ja067047Q  0.331
2007 Fisher M, Abramov M, Van Aerschot A, Xu D, Juliano RL, Herdewijn P. Inhibition of MDR1 expression with altritol-modified siRNAs. Nucleic Acids Research. 35: 1064-74. PMID 17264131 DOI: 10.1093/Nar/Gkl1126  0.381
2007 Juliano RL. Intracellular delivery of oligonucleotide conjugates and dendrimer complexes. Annals of the New York Academy of Sciences. 1082: 18-26. PMID 17145920 DOI: 10.1196/Annals.1348.011  0.421
2005 Kang H, DeLong R, Fisher MH, Juliano RL. Tat-conjugated PAMAM dendrimers as delivery agents for antisense and siRNA oligonucleotides. Pharmaceutical Research. 22: 2099-106. PMID 16184444 DOI: 10.1007/S11095-005-8330-5  0.364
2005 Chaltin P, Margineanu A, Marchand D, Van Aerschot A, Rozenski J, De Schryver F, Herrmann A, Müllen K, Juliano R, Fisher MH, Kang H, De Feyter S, Herdewijn P. Delivery of antisense oligonucleotides using cholesterol-modified sense dendrimers and cationic lipids. Bioconjugate Chemistry. 16: 827-36. PMID 16029024 DOI: 10.1021/Bc050022G  0.327
2004 Kang H, Fisher MH, Xu D, Miyamoto YJ, Marchand A, Van Aerschot A, Herdewijn P, Juliano RL. Inhibition of MDR1 gene expression by chimeric HNA antisense oligonucleotides. Nucleic Acids Research. 32: 4411-9. PMID 15316104 DOI: 10.1093/Nar/Gkh775  0.359
2003 Laakko T, Juliano RL. Adhesion regulation of stromal cell-derived factor-1 activation of ERK in lymphocytes by phosphatases. The Journal of Biological Chemistry. 278: 31621-8. PMID 12783869 DOI: 10.1074/Jbc.M304700200  0.344
2003 Alahari SK, Reddig PJ, Juliano RL. Biological aspects of signal transduction by cell adhesion receptors. International Review of Cytology. 220: 145-84. PMID 12224548 DOI: 10.1016/S0074-7696(02)20005-4  0.349
2002 Howe AK, Hogan BP, Juliano RL. Regulation of vasodilator-stimulated phosphoprotein phosphorylation and interaction with Abl by protein kinase A and cell adhesion. The Journal of Biological Chemistry. 277: 38121-6. PMID 12087107 DOI: 10.1074/Jbc.M205379200  0.322
2002 Fisher AA, Ye D, Sergueev DS, Fisher MH, Shaw BR, Juliano RL. Evaluating the specificity of antisense oligonucleotide conjugates. A DNA array analysis. The Journal of Biological Chemistry. 277: 22980-4. PMID 11948195 DOI: 10.1074/Jbc.M203347200  0.353
2002 Howe AK, Aplin AE, Juliano RL. Anchorage-dependent ERK signaling--mechanisms and consequences. Current Opinion in Genetics & Development. 12: 30-5. PMID 11790551 DOI: 10.1016/S0959-437X(01)00260-X  0.337
2001 Juliano RL, Aplin AE, Howe AK, Short S, Lee JW, Alahari S. Integrin regulation of receptor tyrosine kinase and G protein-coupled receptor signaling to mitogen-activated protein kinases. Methods in Enzymology. 333: 151-63. PMID 11400332 DOI: 10.1016/S0076-6879(01)33053-7  0.357
2001 Howe AK, Juliano RL. Regulation of anchorage-dependent signal transduction by protein kinase A and p21-activated kinase. Nature Cell Biology. 2: 593-600. PMID 10980699 DOI: 10.1038/35023536  0.316
2000 Parise LV, Lee JW, Juliano RL. New aspects of integrin signaling in cancer Seminars in Cancer Biology. 10: 407-414. PMID 11170863 DOI: 10.1006/Scbi.2000.0337  0.367
2000 Yoo H, Juliano RL. Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers. Nucleic Acids Research. 28: 4225-31. PMID 11058121 DOI: 10.1093/Nar/28.21.4225  0.377
2000 Lee JW, Juliano RL. alpha5beta1 integrin protects intestinal epithelial cells from apoptosis through a phosphatidylinositol 3-kinase and protein kinase B-dependent pathway. Molecular Biology of the Cell. 11: 1973-87. PMID 10848623 DOI: 10.1091/Mbc.11.6.1973  0.326
2000 Astriab-Fisher A, Sergueev DS, Fisher M, Shaw BR, Juliano RL. Antisense inhibition of P-glycoprotein expression using peptide-oligonucleotide conjugates. Biochemical Pharmacology. 60: 83-90. PMID 10807948 DOI: 10.1016/S0006-2952(00)00310-5  0.369
1999 Aplin AE, Short SM, Juliano RL. Anchorage-dependent regulation of the mitogen-activated protein kinase cascade by growth factors is supported by a variety of integrin alpha chains. The Journal of Biological Chemistry. 274: 31223-8. PMID 10531317 DOI: 10.1074/Jbc.274.44.31223  0.304
1999 Juliano RL, Alahari S, Yoo H, Kole R, Cho M. Antisense pharmacodynamics: Critical issues in the transport and delivery of antisense oligonucleotides Pharmaceutical Research. 16: 494-502. PMID 10227702 DOI: 10.1023/A:1011958726518  0.335
1998 Keely P, Parise L, Juliano R. Integrins and GTPases in tumour cell growth, motility and invasion. Trends in Cell Biology. 8: 101-6. PMID 9695818 DOI: 10.1016/S0962-8924(97)01219-1  0.36
1998 Short SM, Talbott GA, Juliano RL. Integrin-mediated signaling events in human endothelial cells. Molecular Biology of the Cell. 9: 1969-80. PMID 9693360 DOI: 10.1091/Mbc.9.8.1969  0.363
1998 Howe A, Aplin AE, Alahari SK, Juliano RL. Integrin signaling and cell growth control. Current Opinion in Cell Biology. 10: 220-31. PMID 9561846 DOI: 10.1016/S0955-0674(98)80144-0  0.363
1997 Juliano R. Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 18: 911-7. PMID 8939069 DOI: 10.1002/Bies.950181110  0.341
1995 Varner JA, Emerson DA, Juliano RL. Integrin alpha 5 beta 1 expression negatively regulates cell growth: reversal by attachment to fibronectin. Molecular Biology of the Cell. 6: 725-40. PMID 7579691 DOI: 10.1091/Mbc.6.6.725  0.319
1992 Akhtar S, Juliano RL. Cellular uptake and intracellular fate of antisense oligonucleotides Trends in Cell Biology. 2: 139-144. PMID 14731968 DOI: 10.1016/0962-8924(92)90100-2  0.4
1991 Shoji Y, Fisher MH, Periasamy A, Herman B, Juliano RL. Verapamil and cyclosporin A modulate doxorubicin toxicity by distinct mechanisms. Cancer Letters. 57: 209-18. PMID 2032209 DOI: 10.1016/0304-3835(91)90159-F  0.321
1990 Sczekan MM, Juliano RL. Internalization of the fibronectin receptor is a constitutive process. Journal of Cellular Physiology. 142: 574-80. PMID 2138162 DOI: 10.1002/Jcp.1041420317  0.309
1990 Juliano R, Daoud SS. Liposomes as a delivery system for membrane-active antitumor drugs Journal of Controlled Release. 11: 225-232. DOI: 10.1016/0168-3659(90)90135-G  0.341
1989 Daoud SS, Juliano RL. In vitro effect of liposome-incorporated valinomycin on growth and macromolecular synthesis of normal and ras-transformed 3T3 cells. Cancer Chemotherapy and Pharmacology. 23: 151-5. PMID 2647310 DOI: 10.1007/Bf00267946  0.322
1988 Juliano R. Factors affecting the clearance kinetics and tissue distribution of liposomes, microspheres and emulsions Advanced Drug Delivery Reviews. 2: 31-54. DOI: 10.1016/0169-409X(88)90004-X  0.326
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