| Year |
Citation |
Score |
| 2020 |
Sartorius CA, Horwitz KB. Response to: Progesterone and breast cancer pathogenesis. Journal of Molecular Endocrinology. PMID 33112797 DOI: 10.1530/JME-20-0296 |
0.518 |
|
| 2020 |
Horwitz KB, Sartorius CA. Progesterone and Progesterone Receptors in Breast Cancer: Past, Present, Future. Journal of Molecular Endocrinology. PMID 32485679 DOI: 10.1530/JME-20-0104 |
0.551 |
|
| 2020 |
Brechbuhl HM, Barrett AS, Kopin E, Hagen JC, Han AL, Gillen AE, Finlay-Schultz J, Cittelly DM, Owens P, Horwitz KB, Sartorius CA, Hansen KC, Kabos P. Fibroblast subtypes define a metastatic matrisome in breast cancer. Jci Insight. PMID 32045383 DOI: 10.1172/Jci.Insight.130751 |
0.56 |
|
| 2018 |
Abdel-Hafiz HA, Dudevoir ML, Perez D, Abdel-Hafiz M, Horwitz KB. SUMOylation Regulates Transcription by the Progesterone Receptor A Isoform in a Target Gene Selective Manner. Diseases (Basel, Switzerland). 6. PMID 29301281 DOI: 10.3390/diseases6010005 |
0.564 |
|
| 2015 |
Abdel-Hafiz HA, Horwitz KB. Role of epigenetic modifications in luminal breast cancer. Epigenomics. 7: 847-62. PMID 25689414 DOI: 10.2217/epi.15.10 |
0.42 |
|
| 2014 |
Ogba N, Manning NG, Bliesner BS, Ambler SK, Haughian JM, Pinto MP, Jedlicka P, Joensuu K, Heikkilä P, Horwitz KB. Luminal breast cancer metastases and tumor arousal from dormancy are promoted by direct actions of estradiol and progesterone on the malignant cells. Breast Cancer Research : Bcr. 16: 489. PMID 25475897 DOI: 10.1186/S13058-014-0489-4 |
0.616 |
|
| 2014 |
Pinto MP, Dye WW, Jacobsen BM, Horwitz KB. Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling. Bmc Cancer. 14: 735. PMID 25274034 DOI: 10.1186/1471-2407-14-735 |
0.672 |
|
| 2014 |
Knox AJ, Scaling AL, Pinto MP, Bliesner BS, Haughian JM, Abdel-Hafiz HA, Horwitz KB. Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease. Breast Cancer Research : Bcr. 16: 418. PMID 25116921 DOI: 10.1186/S13058-014-0418-6 |
0.587 |
|
| 2014 |
Abdel-Hafiz HA, Horwitz KB. Post-translational modifications of the progesterone receptors. The Journal of Steroid Biochemistry and Molecular Biology. 140: 80-9. PMID 24333793 DOI: 10.1016/j.jsbmb.2013.12.008 |
0.411 |
|
| 2014 |
Chan DC, Zhang Z, Zheng D, Chan T, Berg M, Horwitz K, Ahn N, Lanier L, Bunn P. Abstract 4836: Immune-tolerance due to aberrant expression of Natural Killer-Cell Immunoglobulin-like Receptors (KIRs) on cancer cells and enhanced cancer-platelet interactions Cancer Research. 74: 4836-4836. DOI: 10.1158/1538-7445.Am2014-4836 |
0.495 |
|
| 2013 |
Joensuu K, Leidenius M, Kero M, Andersson LC, Horwitz KB, Heikkilä P. ER, PR, HER2, Ki-67 and CK5 in Early and Late Relapsing Breast Cancer-Reduced CK5 Expression in Metastases. Breast Cancer : Basic and Clinical Research. 7: 23-34. PMID 23514931 DOI: 10.4137/BCBCR.S10701 |
0.595 |
|
| 2013 |
Harvell DM, Kim J, O'Brien J, Tan AC, Borges VF, Schedin P, Jacobsen BM, Horwitz KB. Genomic signatures of pregnancy-associated breast cancer epithelia and stroma and their regulation by estrogens and progesterone. Hormones & Cancer. 4: 140-53. PMID 23479404 DOI: 10.1007/S12672-013-0136-Z |
0.548 |
|
| 2013 |
Jambal P, Badtke MM, Harrell JC, Borges VF, Post MD, Sollender GE, Spillman MA, Horwitz KB, Jacobsen BM. Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features. Breast Cancer Research and Treatment. 137: 431-48. PMID 23247610 DOI: 10.1007/S10549-012-2377-X |
0.762 |
|
| 2012 |
Haughian JM, Pinto MP, Harrell JC, Bliesner BS, Joensuu KM, Dye WW, Sartorius CA, Tan AC, Heikkilä P, Perou CM, Horwitz KB. Maintenance of hormone responsiveness in luminal breast cancers by suppression of Notch. Proceedings of the National Academy of Sciences of the United States of America. 109: 2742-7. PMID 21969591 DOI: 10.1073/Pnas.1106509108 |
0.821 |
|
| 2012 |
Jacobsen BM, Horwitz KB. Progesterone receptors, their isoforms and progesterone regulated transcription. Molecular and Cellular Endocrinology. 357: 18-29. PMID 21952082 DOI: 10.1016/j.mce.2011.09.016 |
0.317 |
|
| 2012 |
Badtke MM, Jambal P, Dye WW, Spillman MA, Post MD, Horwitz KB, Jacobsen BM. Unliganded progesterone receptors attenuate taxane-induced breast cancer cell death by modulating the spindle assembly checkpoint. Breast Cancer Research and Treatment. 131: 75-87. PMID 21340479 DOI: 10.1007/S10549-011-1399-0 |
0.798 |
|
| 2011 |
Pinto MP, Jacobsen BM, Horwitz KB. An immunohistochemical method to study breast cancer cell subpopulations and their growth regulation by hormones in three-dimensional cultures. Frontiers in Endocrinology. 2: 15. PMID 22649363 DOI: 10.3389/fendo.2011.00015 |
0.551 |
|
| 2011 |
Kabos P, Haughian JM, Wang X, Dye WW, Finlayson C, Elias A, Horwitz KB, Sartorius CA. Cytokeratin 5 positive cells represent a steroid receptor negative and therapy resistant subpopulation in luminal breast cancers. Breast Cancer Research and Treatment. 128: 45-55. PMID 20665103 DOI: 10.1007/S10549-010-1078-6 |
0.622 |
|
| 2011 |
Chan DCF, Zhang Z, Wang H, Sui X, Chan TTY, Ahn N, Phillips J, Horwitz K, Lanier L, Bunn P. Abstract 3656: Therapeutic effects of anti-KIR antibodies against metastatic cancer cells with aberrant expression of Natural Killer-Cell Immunoglobulin-like Receptors (KIRs) Cancer Research. 71: 3656-3656. DOI: 10.1158/1538-7445.Am2011-3656 |
0.469 |
|
| 2011 |
Spillman M, Manning N, Dye W, Horwitz K. Ovarian cancer lymph node metastases express unique cellular structure and adhesion genes Gynecologic Oncology. 120. DOI: 10.1016/J.Ygyno.2010.12.126 |
0.388 |
|
| 2010 |
Spillman MA, Manning NG, Dye WW, Sartorius CA, Post MD, Harrell JC, Jacobsen BM, Horwitz KB. Tissue-specific pathways for estrogen regulation of ovarian cancer growth and metastasis. Cancer Research. 70: 8927-36. PMID 20959477 DOI: 10.1158/0008-5472.Can-10-1238 |
0.794 |
|
| 2010 |
Pinto MP, Badtke MM, Dudevoir ML, Harrell JC, Jacobsen BM, Horwitz KB. Vascular endothelial growth factor secreted by activated stroma enhances angiogenesis and hormone-independent growth of estrogen receptor-positive breast cancer. Cancer Research. 70: 2655-64. PMID 20332242 DOI: 10.1158/0008-5472.Can-09-4373 |
0.763 |
|
| 2009 |
Micalizzi DS, Christensen KL, Jedlicka P, Coletta RD, Barón AE, Harrell JC, Horwitz KB, Billheimer D, Heichman KA, Welm AL, Schiemann WP, Ford HL. The Six1 homeoprotein induces human mammary carcinoma cells to undergo epithelial-mesenchymal transition and metastasis in mice through increasing TGF-beta signaling. The Journal of Clinical Investigation. 119: 2678-90. PMID 19726885 DOI: 10.1172/Jci37815 |
0.735 |
|
| 2009 |
Kabos P, Dye W, Elias A, Horwitz K, Sartorius C. The chemoresistant population of luminal subtype human breast cancer cells expresses a basal phenotype. Cancer Research. 69: 42. DOI: 10.1158/0008-5472.Sabcs-42 |
0.701 |
|
| 2008 |
Horwitz KB. The Year in Basic Science: update of estrogen plus progestin therapy for menopausal hormone replacement implicating stem cells in the increased breast cancer risk. Molecular Endocrinology (Baltimore, Md.). 22: 2743-50. PMID 18845670 DOI: 10.1210/me.2008-0291 |
0.552 |
|
| 2008 |
Horwitz KB, Sartorius CA. Progestins in hormone replacement therapies reactivate cancer stem cells in women with preexisting breast cancers: a hypothesis. The Journal of Clinical Endocrinology and Metabolism. 93: 3295-8. PMID 18647813 DOI: 10.1210/jc.2008-0938 |
0.625 |
|
| 2008 |
Lange CA, Sartorius CA, Abdel-Hafiz H, Spillman MA, Horwitz KB, Jacobsen BM. Progesterone receptor action: translating studies in breast cancer models to clinical insights. Advances in Experimental Medicine and Biology. 630: 94-111. PMID 18637487 DOI: 10.1007/978-0-387-78818-0_7 |
0.583 |
|
| 2008 |
Singh M, Spoelstra NS, Jean A, Howe E, Torkko KC, Clark HR, Darling DS, Shroyer KR, Horwitz KB, Broaddus RR, Richer JK. ZEB1 expression in type I vs type II endometrial cancers: a marker of aggressive disease. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 21: 912-23. PMID 18487993 DOI: 10.1038/Modpathol.2008.82 |
0.441 |
|
| 2008 |
Horwitz KB, Dye WW, Harrell JC, Kabos P, Sartorius CA. Rare steroid receptor-negative basal-like tumorigenic cells in luminal subtype human breast cancer xenografts. Proceedings of the National Academy of Sciences of the United States of America. 105: 5774-9. PMID 18391223 DOI: 10.1073/Pnas.0706216105 |
0.802 |
|
| 2008 |
Harvell DM, Richer JK, Singh M, Spoelstra N, Finlayson C, Borges VF, Elias AD, Horwitz KB. Estrogen regulated gene expression in response to neoadjuvant endocrine therapy of breast cancers: tamoxifen agonist effects dominate in the presence of an aromatase inhibitor. Breast Cancer Research and Treatment. 112: 489-501. PMID 18338247 DOI: 10.1007/S10549-008-9923-6 |
0.527 |
|
| 2008 |
Harvell DM, Spoelstra NS, Singh M, McManaman JL, Finlayson C, Phang T, Trapp S, Hunter L, Dye WW, Borges VF, Elias A, Horwitz KB, Richer JK. Molecular signatures of neoadjuvant endocrine therapy for breast cancer: characteristics of response or intrinsic resistance. Breast Cancer Research and Treatment. 112: 475-88. PMID 18327671 DOI: 10.1007/S10549-008-9897-4 |
0.528 |
|
| 2008 |
Harrell JC, Dye WW, Harvell DM, Sartorius CA, Horwitz KB. Contaminating cells alter gene signatures in whole organ versus laser capture microdissected tumors: a comparison of experimental breast cancers and their lymph node metastases. Clinical & Experimental Metastasis. 25: 81-8. PMID 17932773 DOI: 10.1007/S10585-007-9105-7 |
0.762 |
|
| 2007 |
Harrell JC, Dye WW, Harvell DM, Pinto M, Jedlicka P, Sartorius CA, Horwitz KB. Estrogen insensitivity in a model of estrogen receptor positive breast cancer lymph node metastasis. Cancer Research. 67: 10582-91. PMID 17975003 DOI: 10.1158/0008-5472.Can-07-1655 |
0.823 |
|
| 2006 |
Jones MC, Fusi L, Higham JH, Abdel-Hafiz H, Horwitz KB, Lam EW, Brosens JJ. Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone. Proceedings of the National Academy of Sciences of the United States of America. 103: 16272-7. PMID 17053081 DOI: 10.1073/pnas.0603002103 |
0.342 |
|
| 2006 |
Byron SA, Horwitz KB, Richer JK, Lange CA, Zhang X, Yee D. Insulin receptor substrates mediate distinct biological responses to insulin-like growth factor receptor activation in breast cancer cells. British Journal of Cancer. 95: 1220-8. PMID 17043687 DOI: 10.1038/Sj.Bjc.6603354 |
0.395 |
|
| 2006 |
Harrell JC, Dye WW, Allred DC, Jedlicka P, Spoelstra NS, Sartorius CA, Horwitz KB. Estrogen receptor positive breast cancer metastasis: altered hormonal sensitivity and tumor aggressiveness in lymphatic vessels and lymph nodes. Cancer Research. 66: 9308-15. PMID 16982776 DOI: 10.1158/0008-5472.Can-06-1769 |
0.781 |
|
| 2006 |
Jacobsen BM, Harrell JC, Jedlicka P, Borges VF, Varella-Garcia M, Horwitz KB. Spontaneous fusion with, and transformation of mouse stroma by, malignant human breast cancer epithelium. Cancer Research. 66: 8274-9. PMID 16912208 DOI: 10.1158/0008-5472.Can-06-1456 |
0.756 |
|
| 2006 |
Spoelstra NS, Manning NG, Higashi Y, Darling D, Singh M, Shroyer KR, Broaddus RR, Horwitz KB, Richer JK. The transcription factor ZEB1 is aberrantly expressed in aggressive uterine cancers. Cancer Research. 66: 3893-902. PMID 16585218 DOI: 10.1158/0008-5472.Can-05-2881 |
0.459 |
|
| 2006 |
Harvell DM, Richer JK, Allred DC, Sartorius CA, Horwitz KB. Estradiol regulates different genes in human breast tumor xenografts compared with the identical cells in culture. Endocrinology. 147: 700-13. PMID 16239301 DOI: 10.1210/En.2005-0617 |
0.472 |
|
| 2005 |
Ghatge RP, Jacobsen BM, Schittone SA, Horwitz KB. The progestational and androgenic properties of medroxyprogesterone acetate: gene regulatory overlap with dihydrotestosterone in breast cancer cells. Breast Cancer Research : Bcr. 7: R1036-50. PMID 16457685 DOI: 10.1186/Bcr1340 |
0.761 |
|
| 2005 |
Sartorius CA, Harvell DM, Shen T, Horwitz KB. Progestins initiate a luminal to myoepithelial switch in estrogen-dependent human breast tumors without altering growth. Cancer Research. 65: 9779-88. PMID 16266999 DOI: 10.1158/0008-5472.CAN-05-0505 |
0.662 |
|
| 2005 |
Bray JD, Jelinsky S, Ghatge R, Bray JA, Tunkey C, Saraf K, Jacobsen BM, Richer JK, Brown EL, Winneker RC, Horwitz KB, Lyttle CR. Quantitative analysis of gene regulation by seven clinically relevant progestins suggests a highly similar mechanism of action through progesterone receptors in T47D breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 97: 328-41. PMID 16157482 DOI: 10.1016/J.Jsbmb.2005.06.032 |
0.744 |
|
| 2005 |
Fuqua SA, Cui Y, Lee AV, Osborne CK, Horwitz KB. Insights into the role of progesterone receptors in breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 931-2; author reply . PMID 15681552 DOI: 10.1200/JCO.2005.05.152 |
0.546 |
|
| 2005 |
Jacobsen BM, Schittone SA, Richer JK, Horwitz KB. Progesterone-independent effects of human progesterone receptors (PRs) in estrogen receptor-positive breast cancer: PR isoform-specific gene regulation and tumor biology. Molecular Endocrinology (Baltimore, Md.). 19: 574-87. PMID 15563544 DOI: 10.1210/Me.2004-0287 |
0.604 |
|
| 2005 |
Kato S, Pinto M, Carvajal A, Espinoza N, Monso C, Sadarangani A, Villalon M, Brosens JJ, White JO, Richer JK, Horwitz KB, Owen GI. Progesterone increases tissue factor gene expression, procoagulant activity, and invasion in the breast cancer cell line ZR-75-1. The Journal of Clinical Endocrinology and Metabolism. 90: 1181-8. PMID 15562024 DOI: 10.1210/Jc.2004-0857 |
0.555 |
|
| 2004 |
Hopp TA, Weiss HL, Hilsenbeck SG, Cui Y, Allred DC, Horwitz KB, Fuqua SA. Breast cancer patients with progesterone receptor PR-A-rich tumors have poorer disease-free survival rates. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2751-60. PMID 15102680 DOI: 10.1158/1078-0432.CCR-03-0141 |
0.564 |
|
| 2004 |
Wu J, Richer J, Horwitz KB, Hyder SM. Progestin-dependent induction of vascular endothelial growth factor in human breast cancer cells: preferential regulation by progesterone receptor B. Cancer Research. 64: 2238-44. PMID 15026368 DOI: 10.1158/0008-5472.Can-03-3044 |
0.526 |
|
| 2003 |
Jacobsen BM, Richer JK, Sartorius CA, Horwitz KB. Expression profiling of human breast cancers and gene regulation by progesterone receptors. Journal of Mammary Gland Biology and Neoplasia. 8: 257-68. PMID 14973372 DOI: 10.1023/B:Jomg.0000010028.48159.84 |
0.636 |
|
| 2003 |
Sartorius CA, Shen T, Horwitz KB. Progesterone receptors A and B differentially affect the growth of estrogen-dependent human breast tumor xenografts. Breast Cancer Research and Treatment. 79: 287-99. PMID 12846413 |
0.55 |
|
| 2003 |
Qiu M, Olsen A, Faivre E, Horwitz KB, Lange CA. Mitogen-activated protein kinase regulates nuclear association of human progesterone receptors. Molecular Endocrinology (Baltimore, Md.). 17: 628-42. PMID 12554776 DOI: 10.1210/Me.2002-0378 |
0.375 |
|
| 2002 |
Jacobsen BM, Richer JK, Schittone SA, Horwitz KB. New human breast cancer cells to study progesterone receptor isoform ratio effects and ligand-independent gene regulation. The Journal of Biological Chemistry. 277: 27793-800. PMID 12021276 DOI: 10.1074/Jbc.M202584200 |
0.548 |
|
| 2002 |
Richer JK, Jacobsen BM, Manning NG, Abel MG, Wolf DM, Horwitz KB. Differential gene regulation by the two progesterone receptor isoforms in human breast cancer cells. The Journal of Biological Chemistry. 277: 5209-18. PMID 11717311 DOI: 10.1074/Jbc.M110090200 |
0.614 |
|
| 2001 |
Pahl PMB, Horwitz MA, Horwitz KB, Horwitz LD. Desferri-exochelin induces death by apoptosis in human breast cancer cells but does not kill normal breast cells Breast Cancer Research and Treatment. 69: 69-79. PMID 11759830 DOI: 10.1023/A:1012211828319 |
0.548 |
|
| 2001 |
Shen T, Horwitz KB, Lange CA. Transcriptional hyperactivity of human progesterone receptors is coupled to their ligand-dependent down-regulation by mitogen-activated protein kinase-dependent phosphorylation of serine 294. Molecular and Cellular Biology. 21: 6122-31. PMID 11509655 DOI: 10.1128/Mcb.21.18.6122-6131.2001 |
0.456 |
|
| 2000 |
Horwitz K, Clarke C. Estrogens and progestins in mammary development and neoplasia. Introduction. Journal of Mammary Gland Biology and Neoplasia. 3: 1-2. PMID 10819499 DOI: 10.1023/A:1018716732135 |
0.447 |
|
| 2000 |
Hodges YK, Tung L, Yan XD, Graham JD, Horwitz KB, Horwitz LD. Estrogen receptors alpha and beta: prevalence of estrogen receptor beta mRNA in human vascular smooth muscle and transcriptional effects. Circulation. 101: 1792-8. PMID 10769279 DOI: 10.1161/01.CIR.101.15.1792 |
0.308 |
|
| 2000 |
Kinyamu HK, Fryer CJ, Horwitz KB, Archer TK. The mouse mammary tumor virus promoter adopts distinct chromatin structures in human breast cancer cells with and without glucocorticoid receptor. The Journal of Biological Chemistry. 275: 20061-8. PMID 10751396 DOI: 10.1074/jbc.M001142200 |
0.464 |
|
| 2000 |
Lange CA, Shen T, Horwitz KB. Phosphorylation of human progesterone receptors at serine-294 by mitogen-activated protein kinase signals their degradation by the 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. 97: 1032-7. PMID 10655479 DOI: 10.1073/Pnas.97.3.1032 |
0.301 |
|
| 2000 |
Horwitz K. Growth regulation and steroid hormone resistance in breast cancer Breast Cancer Research. 2: 1-2. DOI: 10.1186/Bcr132 |
0.595 |
|
| 2000 |
Lange C, Shen T, Horwitz K. Phosphorylation of human progesterone receptors by MAPKs mediates transcriptional synergy between progestins and MEKK1 in human breast cancer cells Breast Cancer Research. 2: 1-2. DOI: 10.1186/Bcr104 |
0.615 |
|
| 1999 |
Takimoto GS, Graham JD, Jackson TA, Tung L, Powell RL, Horwitz LD, Horwitz KB. Tamoxifen resistant breast cancer: coregulators determine the direction of transcription by antagonist-occupied steroid receptors. The Journal of Steroid Biochemistry and Molecular Biology. 69: 45-50. PMID 10418980 DOI: 10.1016/S0960-0760(98)00148-4 |
0.455 |
|
| 1999 |
Lange CA, Richer JK, Horwitz KB. Hypothesis: Progesterone primes breast cancer cells for cross-talk with proliferative or antiproliferative signals. Molecular Endocrinology (Baltimore, Md.). 13: 829-36. PMID 10379882 DOI: 10.1210/Mend.13.6.0290 |
0.585 |
|
| 1999 |
Hodges YK, Richer JK, Horwitz KB, Horwitz LD. Variant estrogen and progesterone receptor messages in human vascular smooth muscle. Circulation. 99: 2688-93. PMID 10338464 DOI: 10.1161/01.Cir.99.20.2688 |
0.389 |
|
| 1998 |
Richer JK, Lange CA, Manning NG, Owen G, Powell R, Horwitz KB. Convergence of progesterone with growth factor and cytokine signaling in breast cancer. Progesterone receptors regulate signal transducers and activators of transcription expression and activity. The Journal of Biological Chemistry. 273: 31317-26. PMID 9813040 DOI: 10.1074/Jbc.273.47.31317 |
0.458 |
|
| 1998 |
Lange CA, Richer JK, Shen T, Horwitz KB. Convergence of progesterone and epidermal growth factor signaling in breast cancer. Potentiation of mitogen-activated protein kinase pathways. The Journal of Biological Chemistry. 273: 31308-16. PMID 9813039 DOI: 10.1074/Jbc.273.47.31308 |
0.432 |
|
| 1998 |
Richer JK, Lange CA, Wierman AM, Brooks KM, Tung L, Takimoto GS, Horwitz KB. Progesterone receptor variants found in breast cells repress transcription by wild-type receptors. Breast Cancer Research and Treatment. 48: 231-41. PMID 9598870 DOI: 10.1023/A:1005941117247 |
0.594 |
|
| 1998 |
Owen GI, Richer JK, Tung L, Takimoto G, Horwitz KB. Progesterone regulates transcription of the p21(WAF1) cyclin- dependent kinase inhibitor gene through Sp1 and CBP/p300. The Journal of Biological Chemistry. 273: 10696-701. PMID 9553133 DOI: 10.1074/Jbc.273.17.10696 |
0.338 |
|
| 1998 |
Leslie K, Kumar N, Litman E, Richter J, Owen G, Horwitz K. Progesterone receptor isoform B is a strong transcriptional activator and a potential marker for well-differentiated endometrial cancer cells Journal of the Society For Gynecologic Investigation. 5. DOI: 10.1016/S1071-5576(97)86223-5 |
0.508 |
|
| 1997 |
Leslie KK, Kumar NS, Richer J, Owen G, Takimoto G, Horwitz KB, Lange C. Differential expression of the A and B isoforms of progesterone receptor in human endometrial cancer cells. Only progesterone receptor B is induced by estrogen and associated with strong transcriptional activation. Annals of the New York Academy of Sciences. 828: 17-26. PMID 9329820 DOI: 10.1111/J.1749-6632.1997.Tb48520.X |
0.401 |
|
| 1997 |
Groshong SD, Owen GI, Grimison B, Schauer IE, Todd MC, Langan TA, Sclafani RA, Lange CA, Horwitz KB. Biphasic regulation of breast cancer cell growth by progesterone: role of the cyclin-dependent kinase inhibitors, p21 and p27(Kip1). Molecular Endocrinology (Baltimore, Md.). 11: 1593-607. PMID 9328342 DOI: 10.1210/Mend.11.11.0006 |
0.451 |
|
| 1997 |
Miller MM, James RA, Richer JK, Gordon DF, Wood WM, Horwitz KB. Progesterone regulated expression of flavin-containing monooxygenase 5 by the B-isoform of progesterone receptors: implications for tamoxifen carcinogenicity. The Journal of Clinical Endocrinology and Metabolism. 82: 2956-61. PMID 9284726 DOI: 10.1210/jcem.82.9.4239 |
0.506 |
|
| 1995 |
Horwitz KB. When tamoxifen turns bad. Endocrinology. 136: 821-3. PMID 7867589 DOI: 10.1210/endo.136.3.7867589 |
0.329 |
|
| 1994 |
Sartorius CA, Melville MY, Hovland AR, Tung L, Takimoto GS, Horwitz KB. A third transactivation function (AF3) of human progesterone receptors located in the unique N-terminal segment of the B-isoform. Molecular Endocrinology (Baltimore, Md.). 8: 1347-60. PMID 7854352 DOI: 10.1210/mend.8.10.7854352 |
0.393 |
|
| 1993 |
Horwitz KB. Mechanisms of hormone resistance in breast cancer. Breast Cancer Research and Treatment. 26: 119-30. PMID 8219249 DOI: 10.1007/BF00689685 |
0.607 |
|
| 1992 |
Leslie K, Tasset D, Horwitz K. Functional analysis of a mutant estrogen receptor isolated from T47Deo breast cancer cells International Journal of Gynecology & Obstetrics. 39: 361-361. DOI: 10.1016/0020-7292(92)90285-Q |
0.576 |
|
| 1990 |
Cappelletti V, Patriarca C, Granata G, Cattoretti G, Coradini D, Di Fronzo G, Horwitz K. Progesterone receptor determination in human breast tumors by immunocytochemical and biochemical techniques. Breast Cancer Research and Treatment. 14: 217-25. PMID 2690973 DOI: 10.1007/Bf01810738 |
0.534 |
|
| 1988 |
Wei LL, Krett NL, Francis MD, Gordon DF, Wood WM, O'Malley BW, Horwitz KB. Multiple human progesterone receptor messenger ribonucleic acids and their autoregulation by progestin agonists and antagonists in breast cancer cells. Molecular Endocrinology (Baltimore, Md.). 2: 62-72. PMID 3398843 DOI: 10.1210/mend-2-1-62 |
0.536 |
|
| 1988 |
Krett NL, Wei LL, Francis MD, Nordeen SK, Gordon DF, Wood WM, Horwitz KB. Human progesterone A-receptors can be synthesized intracellularly and are biologically functional. Biochemical and Biophysical Research Communications. 157: 278-85. PMID 3196338 DOI: 10.1016/S0006-291X(88)80044-5 |
0.316 |
|
| 1987 |
Wei LL, Sheridan PL, Krett NL, Francis MD, Toft DO, Edwards DP, Horwitz KB. Immunologic analysis of human breast cancer progesterone receptors. 2. Structure, phosphorylation, and processing. Biochemistry. 26: 6262-72. PMID 3689774 DOI: 10.1021/Bi00393A046 |
0.319 |
|
| 1986 |
Sedlacek SM, Horwitz KB. The role of progestins and progesterone receptors in the treatment of breast cancer. Steroids. 44: 467-84. PMID 6400150 DOI: 10.1016/S0039-128X(84)80029-X |
0.526 |
|
| 1986 |
Horwitz KB, Pike AW, Gonzalez-Aller C, Fennessey PV. Progesterone metabolism in T47Dco human breast cancer cells--II. Intracellular metabolic path of progesterone and synthetic progestins. Journal of Steroid Biochemistry. 25: 911-6. PMID 3467141 DOI: 10.1016/0022-4731(86)90323-7 |
0.324 |
|
| 1985 |
Horwitz KB. The antiprogestin RU38 486: receptor-mediated progestin versus antiprogestin actions screened in estrogen-insensitive T47Dco human breast cancer cells. Endocrinology. 116: 2236-45. PMID 4039656 DOI: 10.1210/endo-116-6-2236 |
0.42 |
|
| 1983 |
Horwitz KB, Alexander PS. In situ photolinked nuclear progesterone receptors of human breast cancer cells: subunit molecular weights after transformation and translocation. Endocrinology. 113: 2195-201. PMID 6685620 DOI: 10.1210/endo-113-6-2195 |
0.439 |
|
| 1983 |
Lessey BA, Alexander PS, Horwitz KB. The subunit structure of human breast cancer progesterone receptors: characterization by chromatography and photoaffinity labeling. Endocrinology. 112: 1267-74. PMID 6682030 DOI: 10.1210/endo-112-4-1267 |
0.491 |
|
| 1982 |
Horwitz KB. Is a functional estrogen receptor always required for progesterone receptor induction in breast cancer? Journal of Steroid Biochemistry. 15: 209-17. PMID 7339247 DOI: 10.1016/0022-4731(81)90277-6 |
0.507 |
|
| 1982 |
Mockus MB, Lessey BA, Bower MA, Horwitz KB. Estrogen-insensitive progesterone receptors in a human breast cancer cell line: characterization of receptors and of a ligand exchange assay. Endocrinology. 110: 1564-71. PMID 7200421 DOI: 10.1210/endo-110-5-1564 |
0.347 |
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| 1982 |
Horwitz KB, Mockus MB, Lessey BA. Variant T47D human breast cancer cells with high progesterone-receptor levels despite estrogen and antiestrogen resistance. Cell. 28: 633-42. PMID 7200400 DOI: 10.1016/0092-8674(82)90218-5 |
0.562 |
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| 1981 |
Horwitz KB, Aiginger P, Kuttenn F, McGuire WL. Nuclear estrogen receptor release from antiestrogen suppression: amplified induction of progesterone receptor in MCF-7 human breast cancer cells. Endocrinology. 108: 1703-9. PMID 7194178 DOI: 10.1210/endo-108-5-1703 |
0.56 |
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| 1980 |
Edwards DP, Martin PM, Horwitz KB, Chamness GC, McGuire WL. Subcellular compartmentalization of estrogen receptors in human breast cancer cells. Experimental Cell Research. 127: 197-213. PMID 7379864 DOI: 10.1016/0014-4827(80)90427-9 |
0.352 |
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| 1980 |
Horwitz KB, McGuire WL. Studies on mechanisms of estrogen and antiestrogen action in human breast cancer. Recent Results in Cancer Research. Fortschritte Der Krebsforschung. Progres Dans Les Recherches Sur Le Cancer. 71: 45-58. PMID 6988916 DOI: 10.1007/978-3-642-81406-8_9 |
0.552 |
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| 1979 |
Horwitz KB, Koseki Y, McGuire WL. Estrogen control of progesterone receptor in human breast cancer: role of estradiol and antiestrogen. Endocrinology. 103: 1742-51. PMID 748014 DOI: 10.1210/endo-103-5-1742 |
0.58 |
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| 1979 |
Horwitz KB, McGuire WL. Estrogen control of progesterone receptor induction in human breast cancer: role of nuclear estrogen receptor. Advances in Experimental Medicine and Biology. 117: 95-110. PMID 474293 DOI: 10.1007/978-1-4757-6589-2_5 |
0.368 |
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| 1979 |
McGuire WL, Horwitz KB. A role for progesterone in breast cancer. Annals of the New York Academy of Sciences. 286: 90-100. PMID 363023 DOI: 10.1111/j.1749-6632.1977.tb29408.x |
0.536 |
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| 1978 |
McGuire WL, Zava DT, Horwitz KB, Garola RE, Chamness GC. Receptors and breast cancer: do we know it all? Journal of Steroid Biochemistry. 9: 461-6. PMID 682638 DOI: 10.1016/0022-4731(78)90616-7 |
0.534 |
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| 1978 |
Martin PM, Horwitz KB, Ryan DS, McGuire WL. Phytoestrogen interaction with estrogen receptors in human breast cancer cells. Endocrinology. 103: 1860-7. PMID 570914 DOI: 10.1210/endo-103-5-1860 |
0.593 |
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| 1978 |
McGuire WL, Horwitz KB, Zava DT, Garola RE, Chamness GC. Hormones in breast cancer: update 1978. Metabolism: Clinical and Experimental. 27: 487-501. PMID 345042 DOI: 10.1016/0026-0495(78)90103-8 |
0.562 |
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| 1977 |
McGuire WL, Horwitz KB, Pearson OH, Segaloff A. Current status of estrogen and progesterone receptors in breast cancer. Cancer. 39: 2934-47. PMID 326386 DOI: 10.1002/1097-0142(197706)39:6<2934::AID-CNCR2820390680>3.0.CO;2-P |
0.56 |
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| 1977 |
Zava DT, Chamness GC, Horwitz KB, McGuire WL. Human breast cancer: biologically active estrogen receptor in the absence of estrogen? Science (New York, N.Y.). 196: 663-4. PMID 193182 DOI: 10.1126/science.193182 |
0.564 |
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| 1976 |
McGuire WL, Horwitz KB, De La Garza M. Selecting endocrine therapy in breast cancer Current Topics in Molecular Endocrinology. 4: 28-35. PMID 1027543 DOI: 10.1007/978-1-4684-2601-4_3 |
0.489 |
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| 1976 |
McGuire WL, Horwitz KB, Chamness GC, Zava DT. A physiological role for estrogen and progesterone in breast cancer. Journal of Steroid Biochemistry. 7: 875-82. PMID 799735 DOI: 10.1016/0022-4731(76)90005-4 |
0.573 |
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| 1976 |
Horwitz KB, Costlow ME, McGuire WL. MCF-7; a human breast cancer cell line with estrogen, androgen, progesterone, and glucocorticoid receptors. Steroids. 26: 785-95. PMID 175527 DOI: 10.1016/0039-128X(75)90110-5 |
0.42 |
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| 1976 |
HORWITZ KB, McGUIRE WL, PEARSON OH, SEGALOFF A. PREDICTING RESPONSE TO ENDOCRINE THERAPY IN HUMAN BREAST CANCER Obstetrical & Gynecological Survey. 31: 142. DOI: 10.1097/00006254-197602000-00017 |
0.469 |
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| 1975 |
Horwitz KB, McGuire WL. Specific progesterone receptors in human breast cancer. Steroids. 25: 497-505. PMID 165596 DOI: 10.1016/0039-128X(75)90027-6 |
0.34 |
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| Low-probability matches (unlikely to be authored by this person) |
| 1991 |
Wei LL, Gonzalez-Aller C, Wood WM, Miller LA, Horwitz KB. 5'-Heterogeneity in human progesterone receptor transcripts predicts a new amino-terminal truncated "C"-receptor and unique A-receptor messages. Molecular Endocrinology (Baltimore, Md.). 4: 1833-40. PMID 2082185 DOI: 10.1210/mend-4-12-1833 |
0.293 |
|
| 1997 |
Jackson TA, Richer JK, Bain DL, Takimoto GS, Tung L, Horwitz KB. The partial agonist activity of antagonist-occupied steroid receptors is controlled by a novel hinge domain-binding coactivator L7/SPA and the corepressors N-CoR or SMRT. Molecular Endocrinology (Baltimore, Md.). 11: 693-705. PMID 9171233 DOI: 10.1210/Mend.11.6.0004 |
0.288 |
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| 1987 |
Estes PA, Suba EJ, Lawler-Heavner J, Elashry-Stowers D, Wei LL, Toft DO, Sullivan WP, Horwitz KB, Edwards DP. Immunologic analysis of human breast cancer progesterone receptors. 1. Immunoaffinity purification of transformed receptors and production of monoclonal antibodies. Biochemistry. 26: 6250-62. PMID 3689773 DOI: 10.1021/Bi00393A045 |
0.286 |
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| 2006 |
Tung L, Abdel-Hafiz H, Shen T, Harvell DM, Nitao LK, Richer JK, Sartorius CA, Takimoto GS, Horwitz KB. Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B. Molecular Endocrinology (Baltimore, Md.). 20: 2656-70. PMID 16762974 DOI: 10.1210/Me.2006-0105 |
0.284 |
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| 2000 |
Sartorius CA, Takimoto GS, Richer JK, Tung L, Horwitz KB. Association of the Ku autoantigen/DNA-dependent protein kinase holoenzyme and poly(ADP-ribose) polymerase with the DNA binding domain of progesterone receptors. Journal of Molecular Endocrinology. 24: 165-82. PMID 10750018 DOI: 10.1677/Jme.0.0240165 |
0.275 |
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| 2009 |
Abdel-Hafiz H, Dudevoir ML, Horwitz KB. Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation. The Journal of Biological Chemistry. 284: 9099-108. PMID 19211567 DOI: 10.1074/jbc.M805226200 |
0.258 |
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| 1982 |
Horwitz KB, Horwitz LD. Canine vascular tissues are targets for androgens, estrogens, progestins, and glucocorticoids. The Journal of Clinical Investigation. 69: 750-8. PMID 6281310 DOI: 10.1172/JCI110513 |
0.253 |
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| 2012 |
Abdel-Hafiz HA, Horwitz KB. Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation. Bmc Molecular Biology. 13: 10. PMID 22439847 DOI: 10.1186/1471-2199-13-10 |
0.248 |
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| 1985 |
Horwitz KB, Francis MD, Wei LL. Hormone-dependent covalent modification and processing of human progesterone receptors in the nucleus. Dna (Mary Ann Liebert, Inc.). 4: 451-60. PMID 4092571 DOI: 10.1089/dna.1985.4.451 |
0.247 |
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| 1999 |
Horwitz KB. Bringing estrogen receptors under control. Breast Cancer Research : Bcr. 1: 5-7. PMID 11250673 DOI: 10.1186/bcr3 |
0.245 |
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| 1992 |
Takimoto GS, Tasset DM, Eppert AC, Horwitz KB. Hormone-induced progesterone receptor phosphorylation consists of sequential DNA-independent and DNA-dependent stages: analysis with zinc finger mutants and the progesterone antagonist ZK98299. Proceedings of the National Academy of Sciences of the United States of America. 89: 3050-4. PMID 1557412 DOI: 10.1073/pnas.89.7.3050 |
0.24 |
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| 2002 |
Abdel-Hafiz H, Takimoto GS, Tung L, Horwitz KB. The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression. The Journal of Biological Chemistry. 277: 33950-6. PMID 12114521 DOI: 10.1074/jbc.M204573200 |
0.234 |
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| 2006 |
Chadli A, Graham JD, Abel MG, Jackson TA, Gordon DF, Wood WM, Felts SJ, Horwitz KB, Toft D. GCUNC-45 is a novel regulator for the progesterone receptor/hsp90 chaperoning pathway. Molecular and Cellular Biology. 26: 1722-30. PMID 16478993 DOI: 10.1128/Mcb.26.5.1722-1730.2006 |
0.227 |
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| 1988 |
Sheridan PL, Krett NL, Gordon JA, Horwitz KB. Human progesterone receptor transformation and nuclear down-regulation are independent of phosphorylation. Molecular Endocrinology (Baltimore, Md.). 2: 1329-42. PMID 3063956 DOI: 10.1210/mend-2-12-1329 |
0.198 |
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| 1986 |
Horwitz KB, Wei LL, Francis MD. Structural analyses of progesterone receptors. Journal of Steroid Biochemistry. 24: 109-17. PMID 3702401 DOI: 10.1016/0022-4731(86)90039-7 |
0.186 |
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| 2009 |
Jacobsen BM, Jambal P, Schittone SA, Horwitz KB. ALU repeats in promoters are position-dependent co-response elements (coRE) that enhance or repress transcription by dimeric and monomeric progesterone receptors. Molecular Endocrinology (Baltimore, Md.). 23: 989-1000. PMID 19372234 DOI: 10.1210/Me.2009-0048 |
0.185 |
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| 1986 |
Wei LL, Horwitz KB. The structure of progesterone receptors. Steroids. 46: 677-95. PMID 3837410 DOI: 10.1016/0039-128X(85)90049-2 |
0.185 |
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| 1994 |
Mohamed MK, Tung L, Takimoto GS, Horwitz KB. The leucine zippers of c-fos and c-jun for progesterone receptor dimerization: A-dominance in the A/B heterodimer. The Journal of Steroid Biochemistry and Molecular Biology. 51: 241-50. PMID 7826885 DOI: 10.1016/0960-0760(94)90036-1 |
0.184 |
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| 1999 |
Nagaya T, Chen KS, Fujieda M, Ohmori S, Richer JK, Horwitz KB, Lupski JR, Seo H. Localization of the human nuclear receptor corepressor (hN-CoR) gene between the CMT1A and the SMS critical regions of chromosome 17p11.2. Genomics. 59: 339-41. PMID 10444336 DOI: 10.1006/Geno.1998.5694 |
0.178 |
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| 1998 |
Hovland AR, Powell RL, Takimoto GS, Tung L, Horwitz KB. An N-terminal inhibitory function, IF, suppresses transcription by the A-isoform but not the B-isoform of human progesterone receptors. The Journal of Biological Chemistry. 273: 5455-60. PMID 9488667 DOI: 10.1074/jbc.273.10.5455 |
0.172 |
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| 1979 |
Zava DT, Landrum B, Horwitz KB, McGuire WL. Androgen receptor assay with [3H]methyltrienolone (R1881) in the presence of progesterone receptors. Endocrinology. 104: 1007-12. PMID 436741 DOI: 10.1210/endo-104-4-1007 |
0.172 |
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| 1996 |
Takimoto GS, Hovland AR, Tasset DM, Melville MY, Tung L, Horwitz KB. Role of phosphorylation on DNA binding and transcriptional functions of human progesterone receptors. The Journal of Biological Chemistry. 271: 13308-16. PMID 8662865 DOI: 10.1074/jbc.271.23.13308 |
0.169 |
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| 1993 |
Takimoto GS, Horwitz KB. Progesterone receptor phosphorylation complexities in defining a functional role. Trends in Endocrinology and Metabolism: Tem. 4: 1-7. PMID 18407126 DOI: 10.1016/1043-2760(93)90056-K |
0.167 |
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| 1998 |
Pahl PM, Hodges YK, Meltesen L, Perryman MB, Horwitz KB, Horwitz LD. ZNF207, a ubiquitously expressed zinc finger gene on chromosome 6p21.3. Genomics. 53: 410-2. PMID 9799612 DOI: 10.1006/geno.1998.5442 |
0.162 |
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| 2001 |
Tung L, Shen T, Abel MG, Powell RL, Takimoto GS, Sartorius CA, Horwitz KB. Mapping the unique activation function 3 in the progesterone B-receptor upstream segment. Two LXXLL motifs and a tryptophan residue are required for activity. The Journal of Biological Chemistry. 276: 39843-51. PMID 11546784 DOI: 10.1074/jbc.M106843200 |
0.161 |
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| 1997 |
Petz LN, Nardulli AM, Kim J, Horwitz KB, Freedman LP, Shapiro DJ. DNA bending is induced by binding of the glucocorticoid receptor DNA binding domain and progesterone receptors to their response element. The Journal of Steroid Biochemistry and Molecular Biology. 60: 31-41. PMID 9182856 DOI: 10.1016/S0960-0760(96)00171-9 |
0.155 |
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| 1994 |
Crowley ST, Dempsey EC, Horwitz KB, Horwitz LD. Platelet-induced vascular smooth muscle cell proliferation is modulated by the growth amplification factors serotonin and adenosine diphosphate Circulation. 90: 1908-1918. PMID 7923679 DOI: 10.1161/01.CIR.90.4.1908 |
0.145 |
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| 2003 |
Takimoto GS, Tung L, Abdel-Hafiz H, Abel MG, Sartorius CA, Richer JK, Jacobsen BM, Bain DL, Horwitz KB. Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure. The Journal of Steroid Biochemistry and Molecular Biology. 85: 209-19. PMID 12943706 DOI: 10.1016/S0960-0760(03)00197-3 |
0.136 |
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| 1986 |
Hiatt WR, Travis VL, Horwitz KB, Horwitz LD. The effect of platelet protein and DNA on the measurement of human lymphocyte beta adrenergic receptor number. Journal of Receptor Research. 5: 419-29. PMID 3003354 DOI: 10.3109/10799898509041891 |
0.131 |
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| 2001 |
Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of human progesterone B-receptors: biophysical and biochemical comparison to A-receptors. The Journal of Biological Chemistry. 276: 23825-31. PMID 11328821 DOI: 10.1074/Jbc.M102611200 |
0.129 |
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| 1991 |
Takimoto GS, Tasset DM, Miller LA, Horwitz KB. Epitope mapping of the anti-human progesterone receptor monoclonal antibody, AB-52. The Journal of Steroid Biochemistry and Molecular Biology. 39: 687-92. PMID 1720326 DOI: 10.1016/0960-0760(91)90368-F |
0.123 |
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| 2000 |
Bain DL, Franden MA, McManaman JL, Takimoto GS, Horwitz KB. The N-terminal region of the human progesterone A-receptor. Structural analysis and the influence of the DNA binding domain. The Journal of Biological Chemistry. 275: 7313-20. PMID 10702302 DOI: 10.1074/Jbc.275.10.7313 |
0.088 |
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| Hide low-probability matches. |