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Massimo Trucco - Publications

Affiliations: 
University of Pittsburgh, Pittsburgh, PA, United States 
Area:
Immunology, Molecular Biology, Genetics, Pathology
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Year Citation  Score
2022 Zeleniak A, Trucco M. Central tolerance promoted by cell chimerism. Proceedings of the National Academy of Sciences of the United States of America. 119: e2214989119. PMID 36534805 DOI: 10.1073/pnas.2214989119  0.318
2022 Zeleniak A, Wiegand C, Liu W, McCormick C, K R, Alavi A, Guan H, Bertera S, Lakomy R, Tajima A, Cohen H, Wong S, Balikani L, Mizerak B, Bar-Joseph Z, ... Trucco M, et al. De novo construction of T cell compartment in humanized mice engrafted with iPSC-derived thymus organoids. Nature Methods. PMID 36064772 DOI: 10.1038/s41592-022-01583-3  0.651
2022 Tindall RP, Bertera S, Uemura T, Vincent M, Knoll MF, Knoll CA, Bottino R, Williams H, Trucco M, Thai N. Autologous Islet Transplantation After Total Pancreatectomy in a Patient Recovered from SARS-CoV-2: A Case Report. The American Journal of Case Reports. 23: e935142. PMID 35149668 DOI: 10.12659/AJCR.935142  0.654
2021 Bertera S, Knoll MF, Knoll C, Hara H, Kimbrel EA, Kouris NA, Lanza R, Philips BE, Garciafigueroa Y, Giannoukakis N, Cooper DKC, Trucco M, Bottino R. Human Hemangioblast-Derived Mesenchymal Stem Cells Promote Islet Engraftment in a Minimal Islet Mass Transplantation Model in Mice. Frontiers in Medicine. 8: 660877. PMID 33937296 DOI: 10.3389/fmed.2021.660877  0.691
2021 Aslanoglou D, Bertera S, Sánchez-Soto M, Benjamin Free R, Lee J, Zong W, Xue X, Shrestha S, Brissova M, Logan RW, Wollheim CB, Trucco M, Yechoor VK, Sibley DR, Bottino R, et al. Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Translational Psychiatry. 11: 59. PMID 33589583 DOI: 10.1038/s41398-020-01171-z  0.607
2020 Bertera S, Knoll MF, Knoll CA, Cooper DKC, Trucco M, Bottino R. Pig-to-Macaque Islet Xenotransplantation. Methods in Molecular Biology (Clifton, N.J.). 2110: 289-314. PMID 32002916 DOI: 10.1007/978-1-0716-0255-3_19  0.689
2019 Ali KF, San Martin VT, Walsh RM, Bottino R, Stevens T, Trucco M, Hatipoglu B. Change in Functional Beta Cell Capacity With Time Following Autologous Islet Transplantation. Pancreas. 48: 656-661. PMID 31091212 DOI: 10.1097/Mpa.0000000000001315  0.376
2019 Phillips BE, Garciafigueroa Y, Engman C, Trucco M, Giannoukakis N. Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy. Frontiers in Immunology. 10: 148. PMID 30787930 DOI: 10.3389/Fimmu.2019.00148  0.39
2018 Ali KF, San Martin VT, Stevens T, Walsh RM, Bottino R, Trucco M, Hatipoglu B. Autoimmunity in Autologous Islet Transplantation. Obm Transplantation. 2. PMID 32095782 DOI: 10.21926/obm.transplant.1803014  0.325
2018 Bottino R, Knoll MF, Knoll CA, Bertera S, Trucco MM. The Future of Islet Transplantation Is Now. Frontiers in Medicine. 5: 202. PMID 30057900 DOI: 10.3389/Fmed.2018.00202  0.7
2018 Engman C, Garciafigueroa Y, Phillips BE, Trucco M, Giannoukakis N. Co-Stimulation-Impaired Bone Marrow-Derived Dendritic Cells Prevent Dextran Sodium Sulfate-Induced Colitis in Mice. Frontiers in Immunology. 9: 894. PMID 29774025 DOI: 10.3389/Fimmu.2018.00894  0.378
2018 Menon R, Becker D, Arslanian S, Kordonouri O, Trucco M, Pietropaolo M, Danne T. Editorial Tribute: Mark A. Sperling, MD, Editor-in-Chief, Pediatric Diabetes 2000-2017. Pediatric Diabetes. 19: 345. PMID 29695032 DOI: 10.1111/Pedi.12661  0.372
2018 Bottino R, Pollett JB, Thai N, Trucco M. IMG-1 Activates and Mobilizes Insulin-Producing Islet Progenitor Cells (CD133+/Insulin+) In Vitro Diabetes. 67. DOI: 10.2337/Db18-309-Lb  0.372
2018 PRADHAN I, WONG-NOONAN S, BERTERA S, LAKOMY RJ, COHEN H, WELLS D, TRUCCO M, FAN Y. Prolongation of Allograft Survival by Intrathymic Introduction of Allogeneic Thymic Epithelial Cells Diabetes. 67: 30-OR. DOI: 10.2337/Db18-30-Or  0.704
2017 Phillips BE, Garciafigueroa Y, Trucco M, Giannoukakis N. Clinical Tolerogenic Dendritic Cells: Exploring Therapeutic Impact on Human Autoimmune Disease. Frontiers in Immunology. 8: 1279. PMID 29075262 DOI: 10.3389/Fimmu.2017.01279  0.324
2016 Tajima A, Pradhan I, Geng X, Trucco M, Fan Y. Construction of Thymus Organoids from Decellularized Thymus Scaffolds. Methods in Molecular Biology (Clifton, N.J.). PMID 27730537 DOI: 10.1007/7651_2016_9  0.373
2016 Goyal RK, Lee SJ, Wang T, Trucco M, Haagenson M, Spellman SR, Verneris M, Ferrell RE. Novel HLA-DP region susceptibility loci associated with severe acute GvHD. Bone Marrow Transplantation. PMID 27595289 DOI: 10.1038/Bmt.2016.210  0.309
2016 Tajima A, Liu W, Pradhan I, Bertera S, Lakomy RA, Rudert WA, Trucco M, Meng WS, Fan Y. Promoting 3-D Aggregation of FACS Purified Thymic Epithelial Cells with EAK 16-II/EAKIIH6 Self-assembling Hydrogel. Journal of Visualized Experiments : Jove. PMID 27404995 DOI: 10.3791/54062  0.667
2016 Marré ML, Profozich JL, Coneybeer JT, Geng X, Bertera S, Ford MJ, Trucco M, Piganelli JD. Inherent ER stress in pancreatic islet β cells causes self-recognition by autoreactive T cells in type 1 diabetes. Journal of Autoimmunity. PMID 27173406 DOI: 10.1016/J.Jaut.2016.04.009  0.671
2016 Wang LJ, Kin T, O'Gorman D, Shapiro AM, Naziruddin B, Takita M, Levy MF, Posselt AM, Szot GL, Savari O, Barbaro B, McGarrigle J, Yeh CC, Oberholzer J, Lei J, ... ... Trucco M, et al. A Multicenter Study: North American Islet Donor Score in Donor Pancreas Selection for Human Islet Isolation for Transplantation. Cell Transplantation. PMID 26922947 DOI: 10.3727/096368916X691141  0.356
2015 Bottino R, Trucco M. Use of genetically-engineered pig donors in islet transplantation. World Journal of Transplantation. 5: 243-50. PMID 26722651 DOI: 10.5500/wjt.v5.i4.243  0.342
2015 Nagaraju S, Bertera S, Tanaka T, Hara H, Rayat GR, Wijkstrom M, Ayares D, Trucco M, Cooper DK, Bottino R. In vitro exposure of pig neonatal isletlike cell clusters to human blood. Xenotransplantation. 22: 317-24. PMID 26179209 DOI: 10.1111/Xen.12178  0.67
2015 Bottino R, Trucco M. Clinical implementation of islet transplantation: A current assessment. Pediatric Diabetes. 16: 393-401. PMID 26084669 DOI: 10.1111/pedi.12287  0.352
2015 Fan Y, Tajima A, Goh SK, Geng X, Gualtierotti G, Grupillo M, Coppola A, Bertera S, Rudert WA, Banerjee I, Bottino R, Trucco M. Bioengineering Thymus Organoids to Restore Thymic Function and Induce Donor-Specific Immune Tolerance to Allografts. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1262-77. PMID 25903472 DOI: 10.1038/Mt.2015.77  0.673
2015 Tajima A, Liu W, Pradhan I, Bertera S, Bagia C, Trucco M, Meng WS, Fan Y. Bioengineering mini functional thymic units with EAK16-II/EAKIIH6 self-assembling hydrogel. Clinical Immunology (Orlando, Fla.). PMID 25805654 DOI: 10.1016/J.Clim.2015.03.010  0.628
2015 Johnston PC, Lin YK, Walsh RM, Bottino R, Stevens TK, Trucco M, Bena J, Faiman C, Hatipoglu BA. Factors associated with islet yield and insulin independence after total pancreatectomy and islet cell autotransplantation in patients with chronic pancreatitis utilizing off-site islet isolation: Cleveland Clinic experience. The Journal of Clinical Endocrinology and Metabolism. 100: 1765-70. PMID 25781357 DOI: 10.1210/Jc.2014-4298  0.426
2015 Buryk MA, Dosch HM, Libman I, Arena VC, Huang Y, Cheung RK, Trucco M, Pietropaolo M, Becker DJ. Neuronal T-cell autoreactivity is amplified in overweight children with new-onset insulin-requiring diabetes. Diabetes Care. 38: 43-50. PMID 25414154 DOI: 10.2337/Dc14-1861  0.311
2015 Wijkstrom M, Bottino R, Iwase H, Hara H, Ekser B, van der Windt D, Long C, Toledo FG, Phelps CJ, Trucco M, Cooper DK, Ayares D. Glucose metabolism in pigs expressing human genes under an insulin promoter. Xenotransplantation. 22: 70-9. PMID 25382150 DOI: 10.1111/Xen.12145  0.44
2015 Cedillo M, Libman IM, Arena VC, Zhou L, Trucco M, Ize-Ludlow D, Pietropaolo M, Becker DJ. Obesity, islet cell autoimmunity, and cardiovascular risk factors in youth at onset of type 1 autoimmune diabetes. The Journal of Clinical Endocrinology and Metabolism. 100: E82-6. PMID 25250632 DOI: 10.1210/Jc.2014-2340  0.38
2015 Nagaraju S, Bottino R, Wijkstrom M, Trucco M, Cooper DK. Islet xenotransplantation: what is the optimal age of the islet-source pig? Xenotransplantation. 22: 7-19. PMID 25130196 DOI: 10.1111/Xen.12130  0.421
2014 Nagaraju S, Bertera S, Funair A, Wijkstrom M, Trucco M, Cooper DK, Bottino R. Streptozotocin-associated lymphopenia in cynomolgus monkeys. Islets. 6: e944441. PMID 25322828 DOI: 10.4161/19382014.2014.944441  0.679
2014 Bottino R, Wijkstrom M, van der Windt DJ, Hara H, Ezzelarab M, Murase N, Bertera S, He J, Phelps C, Ayares D, Cooper DK, Trucco M. Pig-to-monkey islet xenotransplantation using multi-transgenic pigs. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 14: 2275-87. PMID 25220221 DOI: 10.1111/Ajt.12868  0.716
2014 Fox IJ, Daley GQ, Goldman SA, Huard J, Kamp TJ, Trucco M. Stem cell therapy. Use of differentiated pluripotent stem cells as replacement therapy for treating disease. Science (New York, N.Y.). 345: 1247391. PMID 25146295 DOI: 10.1126/Science.1247391  0.337
2014 Fan Y, Gualtierotti G, Tajima A, Grupillo M, Coppola A, He J, Bertera S, Owens G, Pietropaolo M, Rudert WA, Trucco M. Compromised central tolerance of ICA69 induces multiple organ autoimmunity. Journal of Autoimmunity. 53: 10-25. PMID 25088457 DOI: 10.1016/J.Jaut.2014.07.001  0.671
2014 Di Caro V, Phillips B, Engman C, Harnaha J, Trucco M, Giannoukakis N. Involvement of suppressive B-lymphocytes in the mechanism of tolerogenic dendritic cell reversal of type 1 diabetes in NOD mice. Plos One. 9: e83575. PMID 24465383 DOI: 10.1371/Journal.Pone.0083575  0.387
2014 Creusot RJ, Giannoukakis N, Trucco M, Clare-Salzler MJ, Fathman CG. It's time to bring dendritic cell therapy to type 1 diabetes. Diabetes. 63: 20-30. PMID 24357690 DOI: 10.2337/Db13-0886  0.443
2014 Bottino R, Nagaraju S, Satyananda V, Hara H, Wijkstrom M, Trucco M, Cooper DKC. Potential for clinical pancreatic islet xenotransplantation Transplant Research and Risk Management. 6: 79-86. DOI: 10.2147/Trrm.S50850  0.474
2013 Nagaraju S, Bottino R, Wijkstrom M, Hara H, Trucco M, Cooper DK. Islet xenotransplantation from genetically engineered pigs. Current Opinion in Organ Transplantation. 18: 695-702. PMID 24126804 DOI: 10.1097/Mot.0000000000000020  0.443
2013 Cooper DK, Hara H, Ezzelarab M, Bottino R, Trucco M, Phelps C, Ayares D, Dai Y. The potential of genetically-engineered pigs in providing an alternative source of organs and cells for transplantation. Journal of Biomedical Research. 27: 249-53. PMID 23885264 DOI: 10.7555/Jbr.27.20130063  0.419
2013 Di Caro V, Phillips B, Engman C, Harnaha J, Trucco M, Giannoukakis N. Retinoic acid-producing, ex-vivo-generated human tolerogenic dendritic cells induce the proliferation of immunosuppressive B lymphocytes. Clinical and Experimental Immunology. 174: 302-17. PMID 23865694 DOI: 10.1111/Cei.12177  0.372
2013 Delmastro-Greenwood MM, Votyakova T, Goetzman E, Marre ML, Previte DM, Tovmasyan A, Batinic-Haberle I, Trucco MM, Piganelli JD. Mn porphyrin regulation of aerobic glycolysis: implications on the activation of diabetogenic immune cells. Antioxidants & Redox Signaling. 19: 1902-15. PMID 23682840 DOI: 10.1089/Ars.2012.5167  0.32
2013 Sklavos MM, Coudriet GM, Delmastro M, Bertera S, Coneybeer JT, He J, Trucco M, Piganelli JD. Administration of a negative vaccination induces hyporesponsiveness to islet allografts. Cell Transplantation. 22: 1147-55. PMID 23031818 DOI: 10.3727/096368912X657233  0.691
2013 Ayares D, Phelps C, Vaught T, Ball S, Monahan J, Walters A, Giraldo A, Bertera S, van der Windt D, Wijkstrom M, Cooper DKC, Bottino R, Trucco M. Multi-transgenic pigs for xenoislet transplantation Xenotransplantation. 20: 46-46. DOI: 10.1111/Xen.12014_5  0.714
2012 Bertera S, Balamurugan AN, Bottino R, He J, Trucco M. Increased yield and improved transplantation outcome of mouse islets with bovine serum albumin. Journal of Transplantation. 2012: 856386. PMID 23304445 DOI: 10.1155/2012/856386  0.708
2012 van der Windt DJ, Bottino R, Kumar G, Wijkstrom M, Hara H, Ezzelarab M, Ekser B, Phelps C, Murase N, Casu A, Ayares D, Lakkis FG, Trucco M, Cooper DK. Clinical islet xenotransplantation: how close are we? Diabetes. 61: 3046-55. PMID 23172951 DOI: 10.2337/Db12-0033  0.437
2012 Giannoukakis N, Trucco M. Dendritic cell therapy for Type 1 diabetes suppression. Immunotherapy. 4: 1063-74. PMID 23148758 DOI: 10.2217/Imt.12.76  0.395
2012 Nti BK, Markman JL, Bertera S, Styche AJ, Lakomy RJ, Subbotin VM, Trucco M, Zorina TD. Treg cells in pancreatic lymph nodes: the possible role in diabetogenesis and β cell regeneration in a T1D model. Cellular & Molecular Immunology. 9: 455-63. PMID 23042535 DOI: 10.1038/Cmi.2012.36  0.712
2012 Giannoukakis N, Trucco M. A role for tolerogenic dendritic cell-induced B-regulatory cells in type 1 diabetes mellitus. Current Opinion in Endocrinology, Diabetes, and Obesity. 19: 279-87. PMID 22760513 DOI: 10.1097/Med.0B013E328355461B  0.411
2012 Walsh RM, Saavedra JR, Lentz G, Guerron AD, Scheman J, Stevens T, Trucco M, Bottino R, Hatipoglu B. Improved quality of life following total pancreatectomy and auto-islet transplantation for chronic pancreatitis. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 16: 1469-77. PMID 22673773 DOI: 10.1007/S11605-012-1914-6  0.31
2012 Schulte BM, Lanke KH, Piganelli JD, Kers-Rebel ED, Bottino R, Trucco M, Huijbens RJ, Radstake TR, Engelse MA, de Koning EJ, Galama JM, Adema GJ, van Kuppeveld FJ. Cytokine and chemokine production by human pancreatic islets upon enterovirus infection. Diabetes. 61: 2030-6. PMID 22596052 DOI: 10.2337/Db11-1547  0.335
2012 Delmastro MM, Styche AJ, Trucco MM, Workman CJ, Vignali DA, Piganelli JD. Modulation of redox balance leaves murine diabetogenic TH1 T cells "LAG-3-ing" behind. Diabetes. 61: 1760-8. PMID 22586584 DOI: 10.2337/db11-1591  0.311
2012 Cifarelli V, Lee S, Kim DH, Zhang T, Kamagate A, Slusher S, Bertera S, Luppi P, Trucco M, Dong HH. FOXO1 mediates the autocrine effect of endothelin-1 on endothelial cell survival. Molecular Endocrinology (Baltimore, Md.). 26: 1213-24. PMID 22570335 DOI: 10.1210/Me.2011-1276  0.683
2012 Bottino R, Bertera S, Grupillo M, Melvin PR, Humar A, Mazariegos G, Moser AJ, Walsh RM, Fung J, Gelrud A, Slivka A, Soltys K, Wijkstrom M, Trucco M. Isolation of human islets for autologous islet transplantation in children and adolescents with chronic pancreatitis. Journal of Transplantation. 2012: 642787. PMID 22461976 DOI: 10.1155/2012/642787  0.688
2012 Bonner SM, Pietropaolo SL, Fan Y, Chang Y, Sethupathy P, Morran MP, Beems M, Giannoukakis N, Trucco G, Palumbo MO, Solimena M, Pugliese A, Polychronakos C, Trucco M, Pietropaolo M. Sequence variation in promoter of Ica1 gene, which encodes protein implicated in type 1 diabetes, causes transcription factor autoimmune regulator (AIRE) to increase its binding and down-regulate expression. The Journal of Biological Chemistry. 287: 17882-93. PMID 22447927 DOI: 10.1074/Jbc.M111.319020  0.416
2012 Grupillo M, Gualtierotti G, He J, Sisino G, Bottino R, Rudert WA, Trucco M, Fan Y. Essential roles of insulin expression in Aire + tolerogenic dendritic cells in maintaining peripheral self-tolerance of islet β-cells Cellular Immunology. 273: 115-123. PMID 22297234 DOI: 10.1016/J.Cellimm.2011.12.010  0.394
2011 Phillips BE, Trucco M. Immunotherapy-based strategies for the treatment of autoimmune diabetes: searching for the cure. Current Pharmaceutical Design. 17: 3217-23. PMID 21864264 DOI: 10.2174/138161211798157603  0.452
2011 Marigliano M, Bertera S, Grupillo M, Trucco M, Bottino R. Pig-to-nonhuman primates pancreatic islet xenotransplantation: an overview. Current Diabetes Reports. 11: 402-12. PMID 21805400 DOI: 10.1007/S11892-011-0213-Z  0.698
2011 Phillips B, Trucco M, Giannoukakis N. Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same? Clinical & Developmental Immunology. 2011: 432016. PMID 21785616 DOI: 10.1155/2011/432016  0.378
2011 Lin MS, Tse HM, Delmastro MM, Bertera S, Wong CT, Lakomy R, He J, Sklavos MM, Coudriet GM, Pietropaolo M, Trucco MM, Piganelli JD. A multivalent vaccine for type 1 diabetes skews T cell subsets to Th2 phenotype in NOD mice. Immunologic Research. 50: 213-20. PMID 21717080 DOI: 10.1007/S12026-011-8215-0  0.658
2011 Giannoukakis N, Phillips B, Finegold D, Harnaha J, Trucco M. Phase I (safety) study of autologous tolerogenic dendritic cells in type 1 diabetic patients. Diabetes Care. 34: 2026-32. PMID 21680720 DOI: 10.2337/Dc11-0472  0.391
2011 Marigliano M, Casu A, Bertera S, Trucco M, Bottino R. Hemoglobin A1C Percentage in Nonhuman Primates: A Useful Tool to Monitor Diabetes before and after Porcine Pancreatic Islet Xenotransplantation. Journal of Transplantation. 2011: 965605. PMID 21559266 DOI: 10.1155/2011/965605  0.696
2011 Stefan M, Simmons RA, Bertera S, Trucco M, Esni F, Drain P, Nicholls RD. Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. American Journal of Physiology. Endocrinology and Metabolism. 300: E909-22. PMID 21343540 DOI: 10.1152/Ajpendo.00185.2010  0.664
2011 Cifarelli V, Trucco M, Luppi P. Anti-inflammatory effects of C-peptide prevent endothelial dysfunction in Type 1 diabetes Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 11: 59-70. DOI: 10.2174/187152211794519403  0.337
2010 Sklavos MM, Bertera S, Tse HM, Bottino R, He J, Beilke JN, Coulombe MG, Gill RG, Crapo JD, Trucco M, Piganelli JD. Redox modulation protects islets from transplant-related injury Diabetes. 59: 1731-1738. PMID 20413509 DOI: 10.2337/Db09-0588  0.666
2010 Morran MP, Casu A, Arena VC, Pietropaolo S, Zhang YJ, Satin LS, Nelson P, Omenn GS, Trucco M, Becker DJ, Pietropaolo M. Humoral autoimmunity against the extracellular domain of the neuroendocrine autoantigen IA-2 heightens the risk of type 1 diabetes. Endocrinology. 151: 2528-37. PMID 20382696 DOI: 10.1210/En.2009-1257  0.349
2010 Potter KJ, Abedini A, Marek P, Klimek AM, Butterworth S, Driscoll M, Baker R, Nilsson MR, Warnock GL, Oberholzer J, Bertera S, Trucco M, Korbutt GS, Fraser PE, Raleigh DP, et al. Islet amyloid deposition limits the viability of human islet grafts but not porcine islet grafts. Proceedings of the National Academy of Sciences of the United States of America. 107: 4305-10. PMID 20160085 DOI: 10.1073/Pnas.0909024107  0.714
2010 Schulte BM, Kramer M, Ansems M, Lanke KH, van Doremalen N, Piganelli JD, Bottino R, Trucco M, Galama JM, Adema GJ, van Kuppeveld FJ. Phagocytosis of enterovirus-infected pancreatic beta-cells triggers innate immune responses in human dendritic cells. Diabetes. 59: 1182-91. PMID 20071599 DOI: 10.2337/Db09-1071  0.431
2009 Phillips B, Giannoukakis N, Trucco M. Dendritic cell-based therapy in Type 1 diabetes mellitus. Expert Review of Clinical Immunology. 5: 325-39. PMID 20477010 DOI: 10.1586/Eci.09.8  0.414
2009 Williams R, Chen YF, Endres R, Middleton D, Trucco M, Williams JD, Knowler W. Molecular variation at the HLA-A, B, C, DRB1, DQA1, and DQB1 loci in full heritage American Indians in Arizona: private haplotypes and their evolution. Tissue Antigens. 74: 520-33. PMID 19845915 DOI: 10.1111/J.1399-0039.2009.01381.X  0.302
2009 Echeverri GJ, McGrath K, Bottino R, Hara H, Dons EM, van der Windt DJ, Ekser B, Casu A, Houser S, Ezzelarab M, Wagner R, Trucco M, Lakkis FG, Cooper DK. Endoscopic gastric submucosal transplantation of islets (ENDO-STI): technique and initial results in diabetic pigs. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 9: 2485-96. PMID 19775318 DOI: 10.1111/J.1600-6143.2009.02815.X  0.407
2009 Fan Y, Rudert WA, Grupillo M, He J, Sisino G, Trucco M. Thymus-specific deletion of insulin induces autoimmune diabetes Embo Journal. 28: 2812-2824. PMID 19680229 DOI: 10.1038/Emboj.2009.212  0.478
2009 Perone MJ, Bertera S, Shufesky WJ, Divito SJ, Montecalvo A, Mathers AR, Larregina AT, Pang M, Seth N, Wucherpfennig KW, Trucco M, Baum LG, Morelli AE. Suppression of autoimmune diabetes by soluble galectin-1. Journal of Immunology (Baltimore, Md. : 1950). 182: 2641-53. PMID 19234158 DOI: 10.4049/Jimmunol.0800839  0.693
2009 Bottino R, Criscimanna A, Casu A, He J, Van der Windt DJ, Rudert WA, Giordano C, Trucco M. Recovery of endogenous beta-cell function in nonhuman primates after chemical diabetes induction and islet transplantation. Diabetes. 58: 442-7. PMID 19001183 DOI: 10.2337/Db08-1127  0.424
2009 Lu Y, Boehm J, Nichol L, Trucco M, Ringquist S. Multiplex HLA-typing by pyrosequencing. Methods in Molecular Biology (Clifton, N.J.). 496: 89-114. PMID 18839107 DOI: 10.1007/978-1-59745-553-4_8  0.314
2008 Pearson T, Shultz LD, Lief J, Burzenski L, Gott B, Chase T, Foreman O, Rossini AA, Bottino R, Trucco M, Greiner DL. A new immunodeficient hyperglycaemic mouse model based on the Ins2Akita mutation for analyses of human islet and beta stem and progenitor cell function. Diabetologia. 51: 1449-56. PMID 18563383 DOI: 10.1007/S00125-008-1057-1  0.371
2008 Rehman KK, Trucco M, Wang Z, Xiao X, Robbins PD. AAV8-mediated gene transfer of interleukin-4 to endogenous beta-cells prevents the onset of diabetes in NOD mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1409-16. PMID 18560422 DOI: 10.1038/Mt.2008.116  0.396
2008 Phillips BE, Giannoukakis N, Trucco M. Dendritic cell mediated therapy for immunoregulation of type 1 diabetes mellitus. Pediatric Endocrinology Reviews : Per. 5: 873-9. PMID 18552749  0.321
2008 Giannoukakis N, Phillips B, Trucco M. Toward a cure for type 1 diabetes mellitus: diabetes-suppressive dendritic cells and beyond. Pediatric Diabetes. 9: 4-13. PMID 18540865 DOI: 10.1111/J.1399-5448.2008.00401.X  0.449
2008 Phillips B, Giannoukakis N, Trucco M. Renal diseases as targets of gene therapy. Contributions to Nephrology. 159: 1-12. PMID 18391581 DOI: 10.1159/000125552  0.317
2008 Jarchum I, Nichol L, Trucco M, Santamaria P, DiLorenzo TP. Identification of novel IGRP epitopes targeted in type 1 diabetes patients. Clinical Immunology (Orlando, Fla.). 127: 359-65. PMID 18358785 DOI: 10.1016/J.Clim.2008.01.015  0.32
2008 Phillips B, Nylander K, Harnaha J, Machen J, Lakomy R, Styche A, Gillis K, Brown L, Lafreniere D, Gallo M, Knox J, Hogeland K, Trucco M, Giannoukakis N. A microsphere-based vaccine prevents and reverses new-onset autoimmune diabetes. Diabetes. 57: 1544-55. PMID 18316361 DOI: 10.2337/Db07-0507  0.463
2008 Cifarelli V, Luppi P, Tse HM, He J, Piganelli J, Trucco M. Human proinsulin C-peptide reduces high glucose-induced proliferation and NF-kappaB activation in vascular smooth muscle cells. Atherosclerosis. 201: 248-57. PMID 18294642 DOI: 10.1016/J.Atherosclerosis.2007.12.060  0.341
2008 King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Woodland RT, Schmidt MR, Woda BA, Thompson MJ, Rossini AA, Greiner DL. A new Hu-PBL model for the study of human islet alloreactivity based on NOD-scid mice bearing a targeted mutation in the IL-2 receptor gamma chain gene. Clinical Immunology (Orlando, Fla.). 126: 303-14. PMID 18096436 DOI: 10.1016/J.Clim.2007.11.001  0.377
2008 Pasquali L, Giannoukakis N, Trucco M. Induction of immune tolerance to facilitate beta cell regeneration in type 1 diabetes. Advanced Drug Delivery Reviews. 60: 106-13. PMID 18053613 DOI: 10.1016/J.Addr.2007.08.032  0.438
2008 Lin M, Wong C, Bertera S, Pignelli J, Tse H, Pietroppaolo M, Milton M, He L, Chang Y, Zhang Y, Lakomy R, Chang J, Trucco M. A Novel Strategy in Prevention and Delay of Type I Diabetes Mellitus (T1DM) Onset by Autoimmunization Journal of Allergy and Clinical Immunology. 121: 792. DOI: 10.1016/J.Jaci.2008.01.043  0.677
2007 Pasquali L, Trucco M, Ringquist S. Navigating pathways affecting type 1 diabetic kidney disease. Pediatric Diabetes. 8: 307-22. PMID 17850474 DOI: 10.1111/J.1399-5448.2007.00257.X  0.337
2007 Rehman KK, Bertera S, Trucco M, Gambotto A, Robbins PD. Immunomodulation by adenoviral-mediated SCD40-Ig gene therapy for mouse allogeneic islet transplantation. Transplantation. 84: 301-7. PMID 17700153 DOI: 10.1097/01.Tp.0000275183.50435.B6  0.687
2007 Trucco M, Casu A, Bottino R. The pig as the donor of pancreatic islets for men. Veterinary Research Communications. 31: 27-33. PMID 17682843 DOI: 10.1007/S11259-007-0006-7  0.488
2007 Trucco M, Giannoukakis N. Immunoregulatory dendritic cells to prevent and reverse new-onset Type 1 diabetes mellitus. Expert Opinion On Biological Therapy. 7: 951-63. PMID 17665986 DOI: 10.1517/14712598.7.7.951  0.432
2007 Geng X, Li L, Bottino R, Balamurugan AN, Bertera S, Densmore E, Su A, Chang Y, Trucco M, Drain P. Antidiabetic sulfonylurea stimulates insulin secretion independently of plasma membrane KATP channels. American Journal of Physiology. Endocrinology and Metabolism. 293: E293-301. PMID 17405830 DOI: 10.1152/Ajpendo.00016.2007  0.636
2007 King M, Pearson T, Shultz LD, Leif J, Bottino R, Trucco M, Atkinson M, Wasserfall C, Herold K, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity Annals of the New York Academy of Sciences. 1103: 90-93. PMID 17376822 DOI: 10.1196/Annals.1394.011  0.328
2007 Liu Z, Dai H, Wan N, Wang T, Bertera S, Trucco M, Dai Z. Suppression of memory CD8 T cell generation and function by tryptophan catabolism. Journal of Immunology (Baltimore, Md. : 1950). 178: 4260-6. PMID 17371982 DOI: 10.4049/Jimmunol.178.7.4260  0.651
2007 Rood PP, Bottino R, Balamurugan AN, Smetanka C, Ayares D, Groth CG, Murase N, Cooper DK, Trucco M. Reduction of early graft loss after intraportal porcine islet transplantation in monkeys. Transplantation. 83: 202-10. PMID 17264817 DOI: 10.1097/01.Tp.0000250680.36942.C6  0.398
2007 Bottino R, Balamurugan AN, Smetanka C, Bertera S, He J, Rood PP, Cooper DK, Trucco M. Isolation outcome and functional characteristics of young and adult pig pancreatic islets for transplantation studies. Xenotransplantation. 14: 74-82. PMID 17214707 DOI: 10.1111/J.1399-3089.2006.00374.X  0.64
2007 Tse HM, Milton MJ, Schreiner S, Profozich JL, Trucco M, Piganelli JD. Disruption of innate-mediated proinflammatory cytokine and reactive oxygen species third signal leads to antigen-specific hyporesponsiveness. Journal of Immunology (Baltimore, Md. : 1950). 178: 908-17. PMID 17202352 DOI: 10.4049/Jimmunol.178.2.908  0.342
2007 Ringquist S, Styche A, Rudert WA, Trucco M. Pyrosequencing-based strategies for improved allele typing of human leukocyte antigen loci. Methods in Molecular Biology (Clifton, N.J.). 373: 115-34. PMID 17185762 DOI: 10.1385/1-59745-377-3:115  0.392
2007 King MA, Pearson T, Shultz LD, Leif JH, Bottino R, Trucco M, Atkinson MA, Wasserfall C, Herold KC, Mordes JP, Rossini AA, Greiner DL. Development of new-generation HU-PBMC-NOD/SCID mice to study human islet alloreactivity Clinical Immunology. 123: 90. DOI: 10.1016/J.Clim.2007.03.374  0.322
2006 Ge X, Piganelli JD, Tse HM, Bertera S, Mathews CE, Trucco M, Wen L, Rudert WA. Modulatory role of DR4- to DQ8-restricted CD4 T-cell responses and type 1 diabetes susceptibility. Diabetes. 55: 3455-62. PMID 17130492 DOI: 10.2337/Db06-0680  0.798
2006 Perone MJ, Bertera S, Tawadrous ZS, Shufesky WJ, Piganelli JD, Baum LG, Trucco M, Morelli AE. Dendritic cells expressing transgenic galectin-1 delay onset of autoimmune diabetes in mice. Journal of Immunology (Baltimore, Md. : 1950). 177: 5278-89. PMID 17015713 DOI: 10.4049/Jimmunol.177.8.5278  0.687
2006 Rood PP, Bottino R, Balamurugan AN, Smetanka C, Ezzelarab M, Busch J, Hara H, Trucco M, Cooper DK. Induction of diabetes in cynomolgus monkeys with high-dose streptozotocin: adverse effects and early responses. Pancreas. 33: 287-92. PMID 17003651 DOI: 10.1097/01.Mpa.0000235307.04110.A2  0.392
2006 Pasquali L, Fan Y, Trucco M, Ringquist S. Rehabilitation of adaptive immunity and regeneration of beta cells Trends in Biotechnology. 24: 516-522. PMID 16963140 DOI: 10.1016/J.Tibtech.2006.08.007  0.416
2006 Trucco M. Is facilitating pancreatic beta cell regeneration a valid option for clinical therapy? Cell Transplantation. 15: S75-84. PMID 16826799 DOI: 10.3727/000000006783982322  0.464
2006 Balamurugan AN, Chang Y, Bertera S, Sands A, Shankar V, Trucco M, Bottino R. Suitability of human juvenile pancreatic islets for clinical use. Diabetologia. 49: 1845-54. PMID 16783471 DOI: 10.1007/S00125-006-0318-0  0.666
2006 Rood PPM, Buhler LH, Bottino R, Trucco M, Cooper DKC. Pig-to-nonhuman primate islet xenotransplantation: A review of current problems Cell Transplantation. 15: 89-104. PMID 16719044 DOI: 10.3727/000000006783982052  0.435
2006 Wang Z, Zhu T, Rehman KK, Bertera S, Zhang J, Chen C, Papworth G, Watkins S, Trucco M, Robbins PD, Li J, Xiao X. Widespread and stable pancreatic gene transfer by adeno-associated virus vectors via different routes. Diabetes. 55: 875-84. PMID 16567506 DOI: 10.2337/Diabetes.55.04.06.Db05-0927  0.663
2006 Takaki T, Marron MP, Mathews CE, Guttmann ST, Bottino R, Trucco M, DiLorenzo TP, Serreze DV. HLA-A*0201-restricted T cells from humanized NOD mice recognize autoantigens of potential clinical relevance to type 1 diabetes. Journal of Immunology (Baltimore, Md. : 1950). 176: 3257-65. PMID 16493087 DOI: 10.4049/Jimmunol.176.5.3257  0.45
2006 Harnaha J, Machen J, Wright M, Lakomy R, Styche A, Trucco M, Makaroun S, Giannoukakis N. Interleukin-7 is a survival factor for CD4+ CD25+ T-cells and is expressed by diabetes-suppressive dendritic cells. Diabetes. 55: 158-70. PMID 16380489 DOI: 10.2337/Diabetes.55.01.06.Db05-0340  0.309
2006 Rood PPM, Bottino R, Balamurugan AN, Fan Y, Cooper DKC, Trucco M. Facilitating physiologic self-regeneration: A step beyond islet cell replacement Pharmaceutical Research. 23: 227-242. PMID 16323065 DOI: 10.1007/s11095-005-9095-6  0.324
2005 Ringquist S, Trucco M. Regenerative medicine for diabetes treatment. Discovery Medicine. 5: 142-7. PMID 20704900  0.31
2005 Pietropaolo M, Yu S, Libman IM, Pietropaolo SL, Riley K, LaPorte RE, Drash AL, Mazumdar S, Trucco M, Becker DJ. Cytoplasmic islet cell antibodies remain valuable in defining risk of progression to type 1 diabetes in subjects with other islet autoantibodies. Pediatric Diabetes. 6: 184-92. PMID 16390386 DOI: 10.1111/J.1399-543X.2005.00127.X  0.408
2005 Bottino R, Trucco M. Multifaceted therapeutic approaches for a multigenic disease. Diabetes. 54: S79-86. PMID 16306345 DOI: 10.2337/Diabetes.54.Suppl_2.S79  0.41
2005 Casu A, Trucco M, Pietropaolo M. A look to the future: prediction, prevention, and cure including islet transplantation and stem cell therapy. Pediatric Clinics of North America. 52: 1779-804. PMID 16301093 DOI: 10.1016/J.Pcl.2005.07.002  0.431
2005 Giannoukakis N, Trucco M. Gene therapy for type 1 diabetes. American Journal of Therapeutics. 12: 512-28. PMID 16280645  0.364
2005 Giannoukakis N, Trucco M. Gene therapy for type 1 diabetes: a proposal to move to the next level. Current Opinion in Molecular Therapeutics. 7: 467-75. PMID 16248282  0.325
2005 Balamurugan AN, He J, Guo F, Stolz DB, Bertera S, Geng X, Ge X, Trucco M, Bottino R. Harmful delayed effects of exogenous isolation enzymes on isolated human islets: relevance to clinical transplantation. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 2671-81. PMID 16212626 DOI: 10.1111/J.1600-6143.2005.01078.X  0.797
2005 Chang Y, Yap S, Ge X, Piganelli J, Bertera S, Giannokakis N, Mathews C, Prud'homme G, Trucco M. DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice. Gene Therapy. 12: 1679-85. PMID 16107864 DOI: 10.1038/Sj.Gt.3302578  0.805
2005 Rao P, Roccisana J, Takane KK, Bottino R, Zhao A, Trucco M, García-Ocaña A. Gene transfer of constitutively active Akt markedly improves human islet transplant outcomes in diabetic severe combined immunodeficient mice. Diabetes. 54: 1664-75. PMID 15919787 DOI: 10.2337/Diabetes.54.6.1664  0.458
2005 Rehman KK, Wang Z, Bottino R, Balamurugan AN, Trucco M, Li J, Xiao X, Robbins PD. Efficient gene delivery to human and rodent islets with double-stranded (ds) AAV-based vectors Gene Therapy. 12: 1313-1323. PMID 15858610 DOI: 10.1038/Sj.Gt.3302530  0.469
2005 Trucco M. Regeneration of the pancreatic beta cell. The Journal of Clinical Investigation. 115: 5-12. PMID 15630433 DOI: 10.1172/Jci23935  0.453
2004 Bertera S, Alexander AM, Crawford ML, Papworth G, Watkins SC, Robbins PD, Trucco M. Gene combination transfer to block autoimmune damage in transplanted islets of Langerhans. Experimental Diabesity Research. 5: 201-10. PMID 15512788 DOI: 10.1080/15438600490486822  0.716
2004 Bottino R, Balamurugan AN, Tse H, Thirunavukkarasu C, Ge X, Profozich J, Milton M, Ziegenfuss A, Trucco M, Piganelli JD. Response of human islets to isolation stress and the effect of antioxidant treatment. Diabetes. 53: 2559-68. PMID 15448084 DOI: 10.2337/Diabetes.53.10.2559  0.791
2004 Machen J, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N. Antisense oligonucleotides down-regulating costimulation confer diabetes-preventive properties to nonobese diabetic mouse dendritic cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 4331-41. PMID 15383562 DOI: 10.4049/Jimmunol.173.7.4331  0.402
2004 Machen J, Bertera S, Chang Y, Bottino R, Balamurugan AN, Robbins PD, Trucco M, Giannoukakis N. Prolongation of islet allograft survival following ex vivo transduction with adenovirus encoding a soluble type 1 TNF receptor-Ig fusion decoy Gene Therapy. 11: 1506-1514. PMID 15229635 DOI: 10.1038/Sj.Gt.3302320  0.728
2004 Barinas-Mitchell E, Pietropaolo S, Zhang YJ, Henderson T, Trucco M, Kuller LH, Pietropaolo M. Islet cell autoimmunity in a triethnic adult population of the Third National Health and Nutrition Examination Survey. Diabetes. 53: 1293-302. PMID 15111499 DOI: 10.2337/Diabetes.53.5.1293  0.38
2004 Ringquist S, Alexander AM, Styche A, Pecoraro C, Rudert WA, Trucco M. HLA class II DRB high resolution genotyping by pyrosequencing: comparison of group specific PCR and pyrosequencing primers. Human Immunology. 65: 163-74. PMID 14969771 DOI: 10.1016/J.Humimm.2003.11.003  0.321
2004 Rehman KK, Wang Z, Bottino R, Balamurugan AN, Li J, Xiao X, Trucco M, Robbins PD. 986. Efficient Gene Delivery to Human and Rodent Islets with Double Stranded (ds)-AAV2-Based Vectors Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.924  0.46
2003 Giannoukakis N, Trucco M. Current status and prospects for gene and cell therapeutics for type 1 diabetes mellitus. Reviews in Endocrine & Metabolic Disorders. 4: 369-380. PMID 14618022 DOI: 10.1023/A:1027306213563  0.401
2003 Bertera S, Geng X, Tawadrous Z, Bottino R, Balamurugan AN, Rudert WA, Drain P, Watkins SC, Trucco M. Body window-enabled in vivo multicolor imaging of transplanted mouse islets expressing an insulin-Timer fusion protein. Biotechniques. 35: 718-22. PMID 14579736 DOI: 10.2144/03354St01  0.714
2003 Dorman JS, Charron-Prochownik D, Siminerio L, Ryan C, Poole C, Becker D, Trucco M. Need for genetic education for type 1 diabetes. Archives of Pediatrics & Adolescent Medicine. 157: 935-6; author reply . PMID 12963603 DOI: 10.1001/Archpedi.157.9.935-A  0.331
2003 Balamurugan AN, Chang Y, Fung JJ, Trucco M, Bottino R. Flexible management of enzymatic digestion improves human islet isolation outcome from sub-optimal donor pancreata. American Journal of Transplantation. 3: 1135-1142. PMID 12919094 DOI: 10.1046/J.1600-6143.2003.00184.X  0.38
2003 Ma L, Qian S, Liang X, Wang L, Woodward JE, Giannoukakis N, Robbins PD, Bertera S, Trucco M, Fung JJ, Lu L. Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity. Diabetes. 52: 1976-85. PMID 12882913 DOI: 10.2337/Diabetes.52.8.1976  0.68
2003 Metes D, Logar A, Rudert WA, Zeevi A, Woodward J, Demetris AJ, Abu-Elmagd K, Eghtesad B, Shapiro R, Fung JJ, Trucco M, Starzl TE, Murase N. Four-color flow cytometric analysis of peripheral blood donor cell chimerism. Human Immunology. 64: 787-95. PMID 12878357 DOI: 10.1016/S0198-8859(03)00113-7  0.367
2003 Zorina TD, Subbotin VM, Bertera S, Alexander AM, Haluszczak C, Gambrell B, Bottino R, Styche AJ, Trucco M. Recovery of the endogenous beta cell function in the NOD model of autoimmune diabetes. Stem Cells (Dayton, Ohio). 21: 377-88. PMID 12832692 DOI: 10.1634/Stemcells.21-4-377  0.74
2003 Starzl TE, Murase N, Abu-Elmagd K, Gray EA, Shapiro R, Eghtesad B, Corry RJ, Jordan ML, Fontes P, Gayowski T, Bond G, Scantlebury VP, Potdar S, Randhawa P, Wu T, ... ... Trucco M, et al. Tolerogenic immunosuppression for organ transplantation. Lancet (London, England). 361: 1502-10. PMID 12737859 DOI: 10.1016/S0140-6736(03)13175-3  0.36
2003 Bottino R, Lemarchand P, Trucco M, Giannoukakis N. Gene- and cell-based therapeutics for type I diabetes mellitus. Gene Therapy. 10: 875-889. PMID 12732873 DOI: 10.1038/Sj.Gt.3302015  0.428
2003 Luppi P, Rudert W, Licata A, Riboni S, Betters D, Cotrufo M, Frati G, Condorelli G, Trucco M. Expansion of specific αβ+ T-cell subsets in the myocardium of patients with myocarditis and idiopathic dilated cardiomyopathy associated with coxsackievirus B infection Human Immunology. 64: 194-210. PMID 12559622 DOI: 10.1016/S0198-8859(02)00798-X  0.372
2003 Bertera S, Crawford ML, Alexander AM, Papworth GD, Watkins SC, Robbins PD, Trucco M. Gene transfer of manganese superoxide dismutase extends islet graft function in a mouse model of autoimmune diabetes. Diabetes. 52: 387-93. PMID 12540612 DOI: 10.2337/Diabetes.52.2.387  0.709
2003 Zanone MM, Catalfamo E, Pietropaolo SL, Rabbone I, Sacchetti C, Cerutti F, Trucco M, Cavallo-Perin P. Glutamic acid decarboxylase and ICA512/IA-2 autoantibodies as disease markers and relationship to residual β-cell function and glycemic control in young type 1 diabetic patients*** Metabolism-Clinical and Experimental. 52: 25-29. PMID 12524658 DOI: 10.1053/Meta.2003.50003  0.379
2003 Rehman KK, Bertera S, Bottino R, Balamurugan AN, Mai JC, Mi Z, Trucco M, Robbins PD. Protection of islets by in situ peptide-mediated transduction of the Ikappa B kinase inhibitor Nemo-binding domain peptide. The Journal of Biological Chemistry. 278: 9862-8. PMID 12524423 DOI: 10.1074/Jbc.M207700200  0.659
2003 Phelps CJ, Koike C, Vaught TD, Boone J, Wells KD, Chen SH, Ball S, Specht SM, Polejaeva IA, Monahan JA, Jobst PM, Sharma SB, Lamborn AE, Garst AS, Moore M, ... ... Trucco M, et al. Production of alpha 1,3-galactosyltransferase-deficient pigs. Science (New York, N.Y.). 299: 411-4. PMID 12493821 DOI: 10.1126/Science.1078942  0.605
2003 Friday RP, Pietropaolo SL, Profozich J, Trucco M, Pietropaolo M. Alternative Core Promoters Regulate Tissue-specific Transcription from the Autoimmune Diabetes-related ICA1 (ICA69) Gene Locus Journal of Biological Chemistry. 278: 853-863. PMID 12409289 DOI: 10.1074/Jbc.M210175200  0.354
2003 Giannoukakis N, Pietropaolo M, Trucco M. Genes and engineered cells as drugs for type I and type II diabetes mellitus therapy and prevention. Current Opinion in Investigational Drugs (London, England : 2000). 3: 735-51. PMID 12090547  0.359
2002 Bottino R, Balamurugan AN, Giannoukakis N, Trucco M. Islet/pancreas transplantation: challenges for pediatrics. Pediatric Diabetes. 3: 210-223. PMID 15016150 DOI: 10.1034/J.1399-5448.2002.30408.X  0.464
2002 Trucco M, Robbins PD, Thomson AW, Giannoukakis N. Gene therapy strategies to prevent autoimmune disorders Current Gene Therapy. 2: 341-354. PMID 12189720 DOI: 10.2174/1566523023347760  0.35
2002 Ma L, Rudert WA, Harnaha J, Wright M, Machen J, Lakomy R, Qian S, Lu L, Robbins PD, Trucco M, Giannoukakis N. Immunosuppressive effects of glucosamine. The Journal of Biological Chemistry. 277: 39343-9. PMID 12176986 DOI: 10.1074/Jbc.M204924200  0.357
2002 Bottino R, Balamurugan AN, Bertera S, Pietropaolo M, Trucco M, Piganelli JD. Preservation of human islet cell functional mass by anti-oxidative action of a novel SOD mimic compound. Diabetes. 51: 2561-7. PMID 12145171 DOI: 10.2337/Diabetes.51.8.2561  0.7
2002 Ringquist S, Alexander AM, Rudert WA, Styche A, Trucco M. Pyrosequence-based typing of alleles of the HLA-DQB1 gene Biotechniques. 33: 166-175. PMID 12139242 DOI: 10.2144/02331Md05  0.348
2002 Zorina TD, Subbotin VM, Bertera S, Alexander AM, Haluszczak C, Styche AJ, Trucco M. Distinct characteristics and features of allogeneic chimerism in the NOD mouse model of autoimmune diabetes. Cell Transplantation. 11: 113-23. PMID 12099635  0.671
2002 Bottino R, Trucco M, Balamurugan AN, Starzl TE. Pancreas and islet cell transplantation. Best Practice & Research in Clinical Gastroenterology. 16: 457-474. PMID 12079269 DOI: 10.1053/Bega.2002.0318  0.471
2002 Pietropaolo M, Becker DJ, LaPorte RE, Dorman JS, Riboni S, Rudert WA, Mazumdar S, Trucco M. Progression to insulin-requiring diabetes in seronegative prediabetic subjects: The role of two HLA-DQ high-risk haplotypes Diabetologia. 45: 66-76. PMID 11845225 DOI: 10.1007/S125-002-8246-5  0.435
2002 Alexander AM, Crawford M, Bertera S, Rudert WA, Takikawa O, Robbins PD, Trucco M. Indoleamine 2,3-dioxygenase expression in transplanted NOD Islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes. 51: 356-65. PMID 11812742 DOI: 10.2337/Diabetes.51.2.356  0.726
2002 Zorina TD, Subbotin VM, Bertera S, Alexander AM, Haluszczak C, Styche AJ, Trucco M. Distinct Characteristics and Features of Allogeneic Chimerism in the NOD Mouse Model of Autoimmune Diabetes Cell Transplantation. 11: 113-123. DOI: 10.3727/096020198389843  0.697
2001 Jankowski RJ, Haluszczak C, Trucco M, Huard J. Flow cytometric characterization of myogenic cell populations obtained via the preplate technique: potential for rapid isolation of muscle-derived stem cells. Human Gene Therapy. 12: 619-28. PMID 11426462 DOI: 10.1089/104303401300057306  0.342
2001 Luppi P, Licata A, Haluszczak C, Rudert WA, Trucco G, McGowan FX, Finegold D, Boyle GJ, Trucco M. Analysis of TCR Vβ repertoire and cytokine gene expression in patients with idiopathic dilated cardiomyopathy Journal of Autoimmunity. 16: 3-13. PMID 11221991 DOI: 10.1006/Jaut.2000.0462  0.327
2000 Starzl TE, Murase N, Demetris A, Trucco M, Fung J. The mystique of hepatic tolerogenicity. Seminars in Liver Disease. 20: 497-510. PMID 11200418 DOI: 10.1055/S-2000-13158  0.357
2000 Giannoukakis N, Mi Z, Rudert WA, Gambotto A, Trucco M, Robbins PD. Prevention of beta cell dysfunction and apoptosis activation in human islets by adenoviral gene transfer of the insulin-like growth factor I. Gene Therapy. 7: 2015-2022. PMID 11175313 DOI: 10.1038/Sj.Gt.3301333  0.364
2000 Luppi P, Zanone MM, Hyoty H, Rudert WA, Haluszczak C, Alexander AM, Bertera S, Becker D, Trucco M. Restricted TCR Vβ gene expression and enterovirus infection in Type I diabetes: A pilot study Diabetologia. 43: 1484-1497. PMID 11151757 DOI: 10.1007/S001250051559  0.71
2000 Winer S, Gunaratnam L, Astsatourov I, Cheung RK, Kubiak V, Karges W, Hammond-McKibben D, Gaedigk R, Graziano D, Trucco M, Becker DJ, Dosch HM. Peptide dose, MHC affinity, and target self-antigen expression are critical for effective immunotherapy of nonobese diabetic mouse prediabetes. Journal of Immunology (Baltimore, Md. : 1950). 165: 4086-94. PMID 11034420 DOI: 10.4049/Jimmunol.165.7.4086  0.8
2000 Okuda T, Ichikawa N, Zhu Y, Chun HJ, Demestris AJ, Nalesnik MA, Rudert B, Trucco M, Starzl TE, Murase N. Quantitative analysis of microchimerism with Y-Chromosome–Specific PCR In Canine Small Bowel Transplantation☆ Transplantation Proceedings. 32: 1278-1278. PMID 10995945 DOI: 10.1016/S0041-1345(00)01223-9  0.357
2000 Giannoukakis N, Rudert WA, Trucco M, Robbins PD. Protection of Human Islets from the Effects of Interleukin-1β by Adenoviral Gene Transfer of an IκB Repressor Journal of Biological Chemistry. 275: 36509-36513. PMID 10967112 DOI: 10.1074/Jbc.M005943200  0.323
2000 Luppi P, Mcknight C, Mathie T, Faas S, Rudert WA, Stewart-Akers AM, Trucco M, Deloia JA. Evidence for superantigen involvement in preeclampsia American Journal of Reproductive Immunology. 43: 187-196. PMID 10836246 DOI: 10.1111/J.8755-8920.2000.430401.X  0.34
2000 Pietropaolo M, Barinas-Mitchell E, Pietropaolo SL, Kuller LH, Trucco M. Evidence of islet cell autoimmunity in elderly patients with type 2 diabetes Diabetes. 49: 32-38. PMID 10615947 DOI: 10.2337/Diabetes.49.1.32  0.424
2000 Bertera S, Alexander A, Giannoukakis N, Robbins PD, Trucco M. Immunology of type 1 diabetes. Intervention and prevention strategies. Endocrinology and Metabolism Clinics of North America. 28: 841-64, x. PMID 10609123 DOI: 10.1016/S0889-8529(05)70105-5  0.703
1999 Luppi P, Trucco M. Immunological models of type 1 diabetes Hormone Research. 52: 1-10. PMID 10640892 DOI: 10.1159/000023424  0.377
1999 Peakman M, Stevens EJ, Lohmann T, Narendran P, Dromey J, Alexander A, Tomlinson AJ, Trucco M, Gorga JC, Chicz RM. Naturally processed and presented epitopes of the islet cell autoantigen IA-2 eluted from HLA-DR4. The Journal of Clinical Investigation. 104: 1449-57. PMID 10562307 DOI: 10.1172/Jci7936  0.381
1999 Giannoukakis N, Rudert WA, Robbins PD, Trucco M. Targeting autoimmune diabetes with gene therapy. Diabetes. 48: 2107-2121. PMID 10535443 DOI: 10.2337/Diabetes.48.11.2107  0.44
1999 Giannoukakis N, Mi Z, Gambotto A, Eramo A, Ricordi C, Trucco M, Robbins PD. Infection of intact human islets by a lentiviral vector. Gene Therapy. 6: 1545-1551. PMID 10490763 DOI: 10.1038/Sj.Gt.3300996  0.401
1999 Giannoukakis N, Rudert WA, Ghivizzani SC, Gambotto A, Ricordi C, Trucco M, Robbins PD. Adenoviral gene transfer of the interleukin-1 receptor antagonist protein to human islets prevents IL-lβ-induced β-cell impairment and activation of islet cell apoptosis in vitro Diabetes. 48: 1730-1736. PMID 10480601 DOI: 10.2337/Diabetes.48.9.1730  0.353
1999 Cope AP, Patel SD, Hall F, Congia M, Hubers HA, Verheijden GF, Boots AM, Menon R, Trucco M, Rijnders AW, Sønderstrup G. T cell responses to a human cartilage autoantigen in the context of rheumatoid arthritis-associated and nonassociated HLA-DR4 alleles. Arthritis and Rheumatism. 42: 1497-507. PMID 10403279 DOI: 10.1002/1529-0131(199907)42:7<1497::Aid-Anr25>3.0.Co;2-#  0.321
1999 Starzl TE, Murase N, Thomson AW, Trucco M, Rao A. Regulation of immune reactivity and tolerance by antigen migration and localization: with particular reference to allo- and xenotransplantation. Transplantation Proceedings. 31: 1806-11. PMID 10371959 DOI: 10.1016/S0041-1345(99)00211-0  0.375
1999 Pugliese A, Kawasaki E, Zeller M, Yu L, Babu S, Solimena M, Moraes CT, Pietropaolo M, Friday RP, Trucco M, Ricordi C, Allen M, Noble JA, Erlich HA, Eisenbarth GS. Sequence analysis of the diabetes-protective human leukocyte antigen-DQB1*0602 allele in unaffected, islet cell antibody-positive first degree relatives and in rare patients with type 1 diabetes. The Journal of Clinical Endocrinology and Metabolism. 84: 1722-8. PMID 10323407 DOI: 10.1210/Jcem.84.5.5684  0.425
1999 Starzl TE, Murase N, Thomson AW, Trucco M, Rao A. Immunity and tolerance are related, and governed by antigen migration and localization. Transplantation Proceedings. 31: 1406-1411. PMID 10083622 DOI: 10.1016/S0041-1345(99)00004-4  0.367
1998 Murphy VJ, Harrison LC, Rudert WA, Luppi P, Trucco M, Fierabracci A, Biro PA, Bottazzo GF. Retroviral superantigens and type 1 diabetes mellitus Cell. 95: 9-11. PMID 9778241 DOI: 10.1016/S0092-8674(00)81775-4  0.376
1998 Luppi P, Rudert WA, Zanone MM, Stassi G, Trucco G, Finegold D, Boyle GJ, Del Nido P, McGowan FX, Trucco M. Idiopathic dilated cardiomyopathy: A superantigen-driven autoimmune disease Circulation. 98: 777-785. PMID 9727548 DOI: 10.1161/01.Cir.98.8.777  0.371
1998 McCanlies E, O'Leary LA, Foley TP, Kramer MK, Burke JP, Libman A, Swan JS, Steenkiste AR, Mccarthy BJ, Trucco M, Dorman JS. Hashimoto's thyroiditis and insulin-dependent diabetes mellitus: differences among individuals with and without abnormal thyroid function. The Journal of Clinical Endocrinology and Metabolism. 83: 1548-51. PMID 9589653 DOI: 10.1210/Jcem.83.5.4769  0.321
1998 Pietropaolo M, Peakman M, Pietropaolo SL, Zanone MM, Foley TP, Becker DJ, Trucco M. Combined analysis of GAD65 and ICA512(IA-2) autoantibodies in organ and non-organ-specific autoimmune diseases confers high specificity for insulin-dependent diabetes mellitus Journal of Autoimmunity. 11: 1-10. PMID 9480718 DOI: 10.1006/Jaut.1997.0170  0.355
1997 Manfras BJ, Rudert WA, Trucco M, Boehm BO. Analysis of the α/β T-cell receptor repertoire by competitive and quantitative family-specific PCR with exogenous standards and high resolution fluorescence based CDR3 size imaging Journal of Immunological Methods. 210: 235-249. PMID 9520306 DOI: 10.1016/S0022-1759(97)00197-X  0.348
1997 Fontes P, Rogers J, Rao AS, Trucco M, Zeevi A, Ricordi C, Fung JJ, Starzl TE. Evidence for engraftment of human bone marrow cells in non-lethally irradiated baboons. Transplantation. 64: 1595-1598. PMID 9415563 DOI: 10.1097/00007890-199712150-00016  0.379
1997 Starzl TE, Eliasziw M, Gjertson D, Terasaki PI, Fung JJ, Trucco M, Martell J, McMichael J, Scantlebury V, Shapiro R, Donner A. HLA and cross-reactive antigen group matching for cadaver kidney allocation. Transplantation. 64: 983-91. PMID 9381546 DOI: 10.1097/00007890-199710150-00009  0.352
1997 Chicz RM, Graziano DF, Trucco M, Strominger JL, Gorga JC. HLA-DP2: Self Peptide Sequences and Binding Properties Journal of Immunology. 159: 4935-4942. PMID 9366419  0.76
1997 Stassi G, Maria RD, Trucco G, Rudert W, Testi R, Galluzzo A, Giordano C, Trucco M. Nitric Oxide Primes Pancreatic β Cells for Fas-mediated Destruction in Insulin-dependent Diabetes Mellitus Journal of Experimental Medicine. 186: 1193-1200. PMID 9334358 DOI: 10.1084/Jem.186.8.1193  0.387
1997 Starzl TE, Demetris AJ, Murase N, Trucco M, Thomson AW, Rao AS, Fung JJ. Chimerism after organ transplantation. Current Opinion in Nephrology and Hypertension. 6: 292-8. PMID 9263673 DOI: 10.1097/00041552-199705000-00015  0.351
1997 Starzl TE, Demetris AJ, Murase N, Trucco M, Thomson AW, Rao AS. The lost chord: microchimerism and allograft survival. Immunology Today. 17: 577-84; discussion 5. PMID 8991290 DOI: 10.1016/S0167-5699(96)10070-0  0.329
1996 Pietropaolo M, Trucco M. Viral elements in autoimmunity of type I diabetes. Trends in Endocrinology and Metabolism. 7: 139-144. PMID 18406740 DOI: 10.1016/1043-2760(96)00037-9  0.39
1996 Park Y, Lee H, Koh CS, Min H, Zimmet PZ, Rowley MJ, Mackay IR, Trucco M, Dorman JS. Low prevalence of immunogenetic markers of IDDM in adult Koreans with diabetes detected on OGTT. Diabetes Research and Clinical Practice. 34: S37-43. PMID 9015668 DOI: 10.1016/S0168-8227(96)90006-6  0.337
1996 Luppi P, Trucco M. Superantigens in insulin-dependent diabetes mellitus Springer Seminars in Immunopathology. 17: 333-362. PMID 8966660 DOI: 10.1007/Bf01795133  0.388
1996 Rao AS, Starzl TE, Demetris AJ, Trucco M, Thomson A, Qian S, Murase N, Fung JJ. The two-way paradigm of transplantation immunology. Clinical Immunology and Immunopathology. 80: S46-51. PMID 8811063 DOI: 10.1006/Clin.1996.0141  0.365
1995 Lampasona V, Ferrari M, Bonifacio E, Pastore MR, Carrera P, Sergi A, Genovese S, Trucco M, Dorman J, Bosi E. HLA-DQ screening for risk assessment of insulin dependent diabetes in northern Italy. Acta Diabetologica. 32: 137-42. PMID 8590780 DOI: 10.1007/Bf00838481  0.415
1995 Shapiro R, Rao AS, Fontes P, Zeevi A, Jordan M, Scantlebury VP, Vivas C, Gritsch HA, Corry RJ, Egidi MF, Rugeles MT, Rilo H, Aitouche A, Demetris AJ, Rosner G, ... Trucco M, et al. Combined simultaneous kidney/bone marrow transplantation. Transplantation. 60: 1421-1425. PMID 8545868 DOI: 10.1097/00007890-199560120-00009  0.315
1995 Luppi P, Rossiello MR, Faas S, Trucco M. Genetic background and environment contribute synergistically to the onset of autoimmune diseases Journal of Molecular Medicine. 73: 381-393. PMID 8528740 DOI: 10.1007/Bf00240137  0.307
1995 Zeevi A, Pavlick M, Lombardozzi S, Banas R, Pappo O, Rao AS, Fontes P, Demetris J, Shapiro R, Dodson F, Trucco M, Carroll P, Pham S, Fung JJ, Starzl TE. Immune Status of Recipients Following Bone Marrow–Augmented Solid Organ Transplantation Transplantation. 59: 616-620. PMID 7878767 DOI: 10.1097/00007890-199502270-00030  0.396
1995 Chicz RM, Lane WS, Robinson RA, Trucco M, Strominger JL, Gorga JC. Self-peptides bound to the type I diabetes associated class II MHC molecules HLA-DQ1 and HLA-DQ8. International Immunology. 6: 1639-49. PMID 7865457 DOI: 10.1093/Intimm/6.11.1639  0.329
1995 Shapiro R, Rao AS, Fontes P, Jordan M, Scantlebury VP, Vivas C, Demetris AJ, Zeevi A, Rybka W, Carroll P, Trucco M, Starzl TE. Combined kidney/bone marrow transplantation--evidence of augmentation of chimerism. Transplantation. 59: 306-309. PMID 7839456 DOI: 10.1097/00007890-199501000-00026  0.35
1995 Kocova M, Blagoevska M, Bogoevski M, Konstantinova M, Dorman J, Trucco M. HLA class II molecular typing in an European Slavic population with a low incidence of insulin-dependent diabetes mellitus. Tissue Antigens. 45: 216-219. PMID 7761980 DOI: 10.1111/J.1399-0039.1995.Tb02442.X  0.387
1995 Lu L, Rudert WA, Qian S, McCaslin D, Fu F, Rao AS, Trucco M, Fung JJ, Starzl TE, Thomson AW. Growth of donor-derived dendritic cells from the bone marrow of murine liver allograft recipients in response to granulocyte/macrophage colony-stimulating factor. The Journal of Experimental Medicine. 182: 379-87. PMID 7629500 DOI: 10.1084/Jem.182.2.379  0.371
1995 Starzl TE, Demetris AJ, Murase N, Trucco M, Thomson AW, Rao AS. The changing immunology of organ transplantation. Hospital Practice (1995). 30: 31-4, 37-42. PMID 7593387 DOI: 10.1080/21548331.1995.11443268  0.373
1995 Trucco M, LaPorte R. Exposure to superantigens as an immunogenetic explanation of type I diabetes mini-epidemics. Journal of Pediatric Endocrinology & Metabolism : Jpem. 8: 3-10. PMID 7584694 DOI: 10.1515/Jpem.1995.8.1.3  0.442
1995 BURLINGHAM WJ, GRAILER AP, FECHNER JH, KUSAKA S, TRUCCO M, KOCOVA M, BELZER FO, SOLLINGER HW. MICROCHIMERISM LINKED TO CYTOTOXIC T LYMPHOCYTE FUNCTIONAL UNRESPONSIVENESS (CLONAL ANERGY) IN A TOLERANT RENAL TRANSPLANT RECIPIENT Transplantation. 59: 1147-1154. DOI: 10.1097/00007890-199504000-00013  0.399
1994 Conrad B, Weidmann E, Trucco G, Rudert WA, Behboo R, Ricordi C, Rodriquez-Rilo H, Finegold D, Trucco M. Evidence for superantigen involvement in insulin-dependent diabetes mellitus aetiology Nature. 371: 351-355. PMID 8090207 DOI: 10.1038/371351A0  0.451
1994 Rudert WA, Kocova M, Rao AS, Trucco M. Fine quantitation by competitive PCR of circulating donor cells in posttransplant chimeric recipients. Transplantation. 58: 964-965. PMID 7940747 DOI: 10.1097/00007890-199410270-00022  0.375
1994 Fontes P, Rao AS, Carroll P, Dodson F, Shapiro R, Tzakis A, Todo S, Abu-Elmagd K, Jordon M, Fung JJ, Starzl TE, Demetris AJ, Zeevi A, Trucco M, Rudert WA, et al. Bone marrow augmentation of donor-cell chimerism in kidney, liver, heart, and pancreas islet transplantation The Lancet. 344: 151-155. PMID 7912764 DOI: 10.1016/S0140-6736(94)92756-1  0.375
1994 Faas S, Trucco M. The genes influencing the susceptibility to IDDM in humans Journal of Endocrinological Investigation. 17: 477-495. PMID 7829823 DOI: 10.1007/Bf03347743  0.419
1993 Starzl TE, Demetris AJ, Trucco M, Zeevi A, Ramos H, Terasaki P, Rudert WA, Kocova M, Ricordi C, Ildstad S, Murase N. Chimerism and donor-specific nonreactivity 27 to 29 years after kidney allotransplantation. Transplantation. 55: 1272-1277. PMID 8516813 DOI: 10.1097/00007890-199306000-00012  0.378
1993 Starzl TE, Demetris AJ, Trucco M, Ricordi C, Ildstad S, Terasaki PI, Murase N, Kendall RS, Kocova M, Rudert WA, Zeevi A, Thiel DV. Chimerism After Liver Transplantation For Type Iv Glycogen Storage Disease And Type 1 Gaucher’S Disease The New England Journal of Medicine. 328: 745-749. PMID 8437594 DOI: 10.1056/Nejm199303183281101  0.363
1993 Starzl TE, Demetris AJ, Murase N, Thomson AW, Trucco M, Ricordi C. Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation. Immunology Today. 14: 326-32. PMID 8397774 DOI: 10.1016/0167-5699(93)90054-O  0.351
1993 Starzl TE, Demetris AJ, Murase N, Thomson AW, Trucco M, Ricordi C. Donor cell chimerism permitted by immunosuppressive drugs: a new view of organ transplantation. Trends in Pharmacological Sciences. 14: 217-23. PMID 8212319 DOI: 10.1016/0165-6147(93)90212-3  0.351
1993 Tong JY, Hsia S, Parris GL, Nghiem DD, Cottington EM, Rudert WA, Trucco M. Molecular compatibility and renal graft survival--the HLA DQB1 genotyping. Transplantation. 55: 390-5. PMID 8094581 DOI: 10.1097/00007890-199302000-00029  0.334
1993 Starzl TE, Fung J, Tzakis A, Todo S, Demetris AJ, Marino IR, Doyle H, Zeevi A, Warty V, Kusne S, Rudert WA, Trucco M, Michaels M. Baboon-to-human liver transplantation The Lancet. 341: 65-71. PMID 8093402 DOI: 10.1016/0140-6736(93)92553-6  0.311
1993 Starzl TE, Murase N, Demetris AJ, Ildstad S, Ricordi C, Trucco M. Allograft and Xenograft Acceptance under FK‐506 and Other Immunosuppressant Treatment Annals of the New York Academy of Sciences. 685: 46-51. PMID 7689809 DOI: 10.1111/J.1749-6632.1993.Tb35849.X  0.33
1993 Starzl TE, Demetris AJ, Trucco M, Murase N, Ricordi C, Ildstad S, Ramos H, Todo S, Tzakis A, Fung JJ, Nalesnik M, Zeevi A, Rudert WA, Kocova M. Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance Hepatology. 17: 1127-1152. DOI: 10.1002/Hep.1840170629  0.369
1992 Boehm BO, Scherbaum WA, Schöffling K, Kühnl P, Althoff P, Manfras B, Usadel KH, Trucco M. Prevalence of HLA-DQ beta chain non-Asp alleles in type I (insulin-dependent) diabetics with young and older ages of onset. Klinische Wochenschrift. 69: 687-9. PMID 1795491 DOI: 10.1007/Bf01649437  0.395
1992 Gutierrez-Lopez MD, Bertera S, Chantres MT, Vavassori C, Dorman JS, Trucco M, Serrano-Rios M. Susceptibility to type 1 (insulin-dependent) diabetes mellitus in Spanish patients correlates quantitatively with expression of HLA-DQ alpha Arg 52 and HLA-DQ beta non-Asp 57 alleles. Diabetologia. 35: 583-8. PMID 1612233 DOI: 10.1007/Bf00400488  0.687
1992 Atlas AB, Finegold DN, Becker D, Trucco M, Kurland G. Diabetic ketoacidosis in cystic fibrosis. American Journal of Diseases of Children (1960). 146: 1457-8. PMID 1456258 DOI: 10.1001/Archpedi.1992.02160240067022  0.376
1992 Lipton RB, Kocova M, LaPorte RE, Dorman JS, Orchard TJ, Riley WJ, Drash AL, Becker DJ, Trucco M. Autoimmunity and genetics contribute to the risk of insulin-dependent diabetes mellitus in families: islet cell antibodies and HLA DQ heterodimers. American Journal of Epidemiology. 136: 503-12. PMID 1442714 DOI: 10.1093/Oxfordjournals.Aje.A116528  0.369
1992 Starzl TE, Ramos H, Zeevi A, Ricordi C, Ildstad S, Murase N, Demetris AJ, Trucco M, Rudert WA, Kocova M. Systemic chimerism in human female recipients of male livers. The Lancet. 340: 876-877. PMID 1357298 DOI: 10.1016/0140-6736(92)93286-V  0.362
1992 Starzl TE, Demetris AJ, Murase N, Ildstad S, Ricordi C, Trucco M. Cell migration, chimerism, and graft acceptance The Lancet. 339: 1579-1582. PMID 1351558 DOI: 10.1016/0140-6736(92)91840-5  0.402
1991 Boehm BO, Manfras B, Rosak C, Schöffling K, Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain is protective against future development of insulin-dependent (type 1) diabetes mellitus. Klinische Wochenschrift. 69: 146-50. PMID 2041376 DOI: 10.1007/Bf01665854  0.43
1991 Boehm BO, Manfras B, Seissler J, Schöffling K, Glück M, Holzberger G, Seidl S, Kühnl P, Trucco M, Scherbaum WA. Epidemiology and immunogenetic background of islet cell antibody--positive nondiabetic schoolchildren. Ulm-Frankfurt population study. Diabetes. 40: 1435-9. PMID 1936604 DOI: 10.2337/Diab.40.11.1435  0.387
1991 Carcassi C, Trucco G, Trucco M, Contu L. A new HLA-DR2 extended haplotype is involved in insulin-dependent diabetes mellitus susceptibility. Human Immunology. 31: 159-164. PMID 1890017 DOI: 10.1016/0198-8859(91)90021-Z  0.362
1991 Contu L, Carcassi C, Trucco M. Diabetes susceptibility in Sardinia The Lancet. 338: 65-65. PMID 1676127 DOI: 10.1016/0140-6736(91)90066-X  0.377
1990 Giorda R, Rudert WA, Vavassori C, Chambers WH, Hiserodt JC, Trucco M. NKR-P1, a signal transduction molecule on natural killer cells Science. 249: 1298-1300. PMID 2399464 DOI: 10.1126/Science.2399464  0.306
1990 Dorman JS, Laporte RE, Stone RA, Trucco M. Worldwide differences in the incidence of type I diabetes are associated with amino acid variation at position 57 of the HLA-DQ β chain Proceedings of the National Academy of Sciences of the United States of America. 87: 7370-7374. PMID 2217170 DOI: 10.1073/Pnas.87.19.7370  0.339
1990 Kuller LH, Becker DJ, Cruickshanks KJ, Dorman JS, Eberhardt MS, Drash AL, LaPorte RE, Lipton R, Moy C, O'Leary LA, Orchard TJ, Rewers M, Songer T, Tajima N, Trucco M, et al. Evolution of the Pittsburgh studies of the epidemiology of insulin-dependent diabetes mellitus Genetic Epidemiology. 7: 105-119. PMID 2186962 DOI: 10.1002/Gepi.1370070202  0.357
1989 Trucco G, Fritsch R, Giorda R, Trucco M. Rapid Detection of IDDM Susceptibility With HLA-DQ β-Alleles as Markers Diabetes. 38: 1617-1622. PMID 2583380 DOI: 10.2337/Diab.38.12.1617  0.354
1989 Sheehy MJ, Meske LM, Emler CA, Rowe JR, Gimenez MHNd, Ingle CA, Chan A, Trucco M, Mak TW. Allelic T-cell receptor α complexes have little or no influence on susceptibility to type 1 diabetes Human Immunology. 26: 261-271. PMID 2573589 DOI: 10.1016/0198-8859(89)90004-9  0.394
1989 Bao MZ, Wang JX, Dorman J, Trucco M. HLA-DQβ NON-ASP-57 ALLELE AND INCIDENCE OF DIABETES IN CHINA AND THE USA The Lancet. 334: 497-498. PMID 2570199 DOI: 10.1016/S0140-6736(89)92102-8  0.384
1988 Morel PA, Dorman JS, Todd JA, McDevitt HO, Trucco M. Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proceedings of the National Academy of Sciences of the United States of America. 85: 8111-5. PMID 3186714 DOI: 10.1073/Pnas.85.21.8111  0.378
1988 Compagnone-Post P, Turco E, Robinson C, Trucco M. The beta-chains of DP4 molecules from different haplotypes are encoded by the same gene. Genomics. 2: 8-13. PMID 2838415 DOI: 10.1016/0888-7543(88)90103-6  0.305
1987 Zeevi A, Cascino I, Di Vecchia L, Marrari M, Duquesnoy R, Trucco M. Alloreactive T-cell recognition of two DQβ allelic specificities associated with DQw1 Human Immunology. 18: 225-234. PMID 2437087 DOI: 10.1016/0198-8859(87)90087-5  0.34
1986 Trucco M, Duquesno R. Polymorphisms of the HLA-DQ subregion Immunology Today. 7: 297-300. PMID 25290846 DOI: 10.1016/0167-5699(86)90065-4  0.316
Low-probability matches (unlikely to be authored by this person)
1994 Manfras BJ, Rudert WA, Trucco M, Böhm BO. A novel strategy for quantitation of T-cell receptor usage in autoimmunity Human Immunology. 40: 34. DOI: 10.1016/0198-8859(94)91726-4  0.3
1996 Faas SJ, Menon R, Braun ER, Rudert WA, Trucco M. Sequence-specific priming and exonuclease-released fluorescence detection of HLA-DQB1 alleles Tissue Antigens. 48: 97-112. PMID 8883299 DOI: 10.1111/J.1399-0039.1996.Tb02614.X  0.299
1981 Richiardi P, Amoroso A, Crepaldi T, Ceppellini R, Trucco M. A xenogeneic monoclonal antibody recognizing specificities controlled by HLA-A and B alleles. Immunogenetics. 12: 615-626. PMID 6783514 DOI: 10.1007/Bf01561701  0.299
2011 Di Caro V, D'Anneo A, Phillips B, Engman C, Harnaha J, Trucco M, Giannoukakis N. Phosphatidylinositol-3-kinase activity during in vitro dendritic cell generation determines suppressive or stimulatory capacity. Immunologic Research. 50: 130-52. PMID 21476100 DOI: 10.1007/S12026-011-8206-1  0.298
2007 Koike C, Uddin M, Wildman DE, Gray EA, Trucco M, Starzl TE, Goodman M. Functionally important glycosyltransferase gain and loss during catarrhine primate emergence. Proceedings of the National Academy of Sciences of the United States of America. 104: 559-64. PMID 17194757 DOI: 10.1073/Pnas.0610012104  0.298
1993 Weidmann E, Elder EM, Trucco M, Lotze MT, Whiteside TL. Usage of T-cell receptor V beta chain genes in fresh and cultured tumor-infiltrating lymphocytes from human melanoma. International Journal of Cancer. 54: 383-90. PMID 8509212 DOI: 10.1002/Ijc.2910540306  0.297
2004 Starzl TE, Murase N, Demetris AJ, Trucco M, Abu-Elmagd K, Gray EA, Eghtesad B, Shapiro R, Marcos A, Fung JJ. Lessons of organ-induced tolerance learned from historical clinical experience. Transplantation. 77: 926-929. PMID 15077039 DOI: 10.1097/01.Tp.0000117780.74133.74  0.296
2017 Bottino R, Knoll MF, Graeme-Wilson J, Klein EC, Ayares D, Trucco M, Cooper DK. Safe use of anti-CD154 monoclonal antibody in pig islet xenotransplantation in monkeys. Xenotransplantation. PMID 28058735 DOI: 10.1111/xen.12283  0.293
2013 Ringquist S, Bellone G, Lu Y, Roeder K, Trucco M. Clustering and alignment of polymorphic sequences for HLA-DRB1 genotyping. Plos One. 8: e59835. PMID 23555798 DOI: 10.1371/Journal.Pone.0059835  0.292
1996 Park Y, Lee H, Koh CS, Min H, Rowley M, Mackay IR, Zimmet P, Mccarthy B, Mccanlies E, Dorman J, Trucco M. The low prevalence of immunogenetic markers in Korean adult-onset IDDM patients. Diabetes Care. 19: 241-245. PMID 8742569 DOI: 10.2337/Diacare.19.3.241  0.291
1991 Dorman JS, Laporte RE, Trucco M. 2 Genes and environment Bailliere's Clinical Endocrinology and Metabolism. 5: 229-245. PMID 1909859 DOI: 10.1016/S0950-351X(05)80125-9  0.29
1994 Ricordi C, Tzakis AG, Zeevi A, Rybka WB, Demetris AJ, Fontes PAC, Nalesnik MA, Trucco M, Ukah FO, Ball ED, Mullen EE, Marino IR, Fung JJ, Starzl TE. Reversal Of Graft-Versus-Host Disease With Infusion Of Autologous Bone Marrow Cell Transplantation. 3: 187-192. PMID 8012734 DOI: 10.1177/096368979400300207  0.29
2011 Grupillo M, Lakomy R, Geng X, Styche A, Rudert WA, Trucco M, Fan Y. An improved intracellular staining protocol for efficient detection of nuclear proteins in YFP-expressing cells Biotechniques. 51: 417-420. PMID 22150333 DOI: 10.2144/000113780  0.29
1997 Menon R, Rudert WA, Braun ER, Jaquins-Gerstl A, Faas SJ, Trucco M. Sequence-specific Priming and Exonuclease-released Fluorescence Assay for Rapid and Reliable HLA-A Molecular Typing. Molecular Diagnosis : a Journal Devoted to the Understanding of Human Disease Through the Clinical Application of Molecular Biology. 2: 99-111. PMID 10462597 DOI: 10.1016/S1084-8592(97)80016-1  0.289
1996 Dorman JS, McCarthy B, McCanlies E, Kramer MK, Vergona RJ, Stone R, Steenkiste AR, Kocova M, Trucco M, Ramos O, Bao MZ, Carrasco E, Garcia De Los Rios M, Lopez G, Tuomilehto J, et al. Molecular IDDM epidemiology: International studies Diabetes Research and Clinical Practice. 34: S107-S116. PMID 9015679 DOI: 10.1016/S0168-8227(96)90017-0  0.289
1994 Tong JY, Hammad A, Rudert WA, Trucco M, Hsia S. Heteroduplexes for HLA DQB1 identity of family members and kidney donor-recipient pairs. Transplantation. 57: 741-745. PMID 7908151 DOI: 10.1097/00007890-199403150-00018  0.289
1993 Manfras BJ, Swinyard M, Rudert WA, Ball EJ, Lee PA, Kühnl P, Trucco M, Böhm BO. Altered CYP21 genes in HLA-haplotypes associated with congenital adrenal hyperplasia (CAH) : a family study Human Genetics. 92: 33-39. PMID 8365724 DOI: 10.1007/Bf00216142  0.288
1992 Trucco M. The natural immune system. The natural killer cell Cell. 71: 717-718. DOI: 10.1016/0092-8674(92)90547-P  0.288
1988 Turco E, Fritsch R, Trucco M. First domain encoding sequence mediates human class II beta-chain gene cross-hybridization. Immunogenetics. 28: 193-204. PMID 2900811 DOI: 10.1007/Bf00375859  0.286
2021 Garciafigueroa Y, Phillips BE, Engman C, Trucco M, Giannoukakis N. Neutrophil-Associated Inflammatory Changes in the Pre-Diabetic Pancreas of Early-Age NOD Mice. Frontiers in Endocrinology. 12: 565981. PMID 33776903 DOI: 10.3389/fendo.2021.565981  0.286
2012 Di Caro V, Giannoukakis N, Trucco M. In vivo delivery of nucleic acid-formulated microparticles as a potential tolerogenic vaccine for type 1 diabetes. The Review of Diabetic Studies : Rds. 9: 348-56. PMID 23804272 DOI: 10.1900/RDS.2012.9.348  0.285
2012 Ekser B, Ezzelarab M, Hara H, van der Windt DJ, Wijkstrom M, Bottino R, Trucco M, Cooper DK. Clinical xenotransplantation: the next medical revolution? Lancet (London, England). 379: 672-83. PMID 22019026 DOI: 10.1016/S0140-6736(11)61091-X  0.284
2015 Giannoukakis N, Trucco M. Cellular therapies based on stem cells and their insulin-producing surrogates: a 2015 reality check. Pediatric Diabetes. 16: 151-63. PMID 25652322 DOI: 10.1111/pedi.12259  0.282
1992 Carcassi C, Giorda R, Trucco M, Contu L. A novel HLA-DR4 haplotype generated by a rare recombinational event between DRB1 and DQA1 loci. Immunogenetics. 36: 338-340. PMID 1644451 DOI: 10.1007/Bf00215664  0.28
1998 Libman IM, Pietropaolo M, LaPorte RE, Trucco M, Becker DJ. Do Black Adolescents with a Diagnosis of IDDM have a Different Type of Diabetes than Whites? • 453 Pediatric Research. 43: 80-80. DOI: 10.1203/00006450-199804001-00474  0.28
2014 Fan Y, Fang X, Tajima A, Geng X, Ranganathan S, Dong H, Trucco M, Sperling MA. Evolution of hepatic steatosis to fibrosis and adenoma formation in liver-specific growth hormone receptor knockout mice. Frontiers in Endocrinology. 5: 218. PMID 25566190 DOI: 10.3389/Fendo.2014.00218  0.279
2011 Caro VD, D'Anneo A, Phillips B, Engman C, Harnaha J, Lakomy R, Styche A, Trucco M, Giannoukakis N. Interleukin-7 matures suppressive CD127(+) forkhead box P3 (FoxP3)(+) T cells into CD127(-) CD25(high) FoxP3(+) regulatory T cells. Clinical and Experimental Immunology. 165: 60-76. PMID 21413939 DOI: 10.1111/J.1365-2249.2011.04334.X  0.278
2002 Koike C, Fung JJ, Geller DA, Kannagi R, Libert T, Luppi P, Nakashima I, Profozich J, Rudert W, Sharma SB, Starzl TE, Trucco M. Molecular basis of evolutionary loss of the α1,3-galactosyltransferase gene in higher primates Journal of Biological Chemistry. 277: 10114-10120. PMID 11773054 DOI: 10.1074/Jbc.M110527200  0.274
2008 Rehman KK, Trucco M, Wang Z, Xiao X, Robbins PD. AAV8-mediated Gene Transfer of Interleukin-4 to Endogenous β-Cells Prevents the Onset of Diabetes in NOD Mice. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1409-1416. PMID 28182870 DOI: 10.1038/mt.2008.116  0.273
2008 He J, Su D, Trucco M. Three-dimensional image study on the vascular structure after angiopoietin-1 transduction in isolated mouse pancreatic islets Proceedings of Spie. 6861: 686114. DOI: 10.1117/12.761320  0.272
2007 Li J, Meinhardt A, Roehrich ME, Golshayan D, Dudler J, Pagnotta M, Trucco M, Vassalli G. Indoleamine 2,3-dioxygenase gene transfer prolongs cardiac allograft survival. American Journal of Physiology. Heart and Circulatory Physiology. 293: H3415-23. PMID 17933973 DOI: 10.1152/ajpheart.00532.2007  0.271
1996 Trucco M, Stassi G. Educating effector T cells Nature. 380: 284-285. PMID 8598923 DOI: 10.1038/380284A0  0.271
2012 van der Windt DJ, Marigliano M, He J, Votyakova TV, Echeverri GJ, Ekser B, Ayares D, Lakkis FG, Cooper DK, Trucco M, Bottino R. Early islet damage after direct exposure of pig islets to blood: has humoral immunity been underestimated? Cell Transplantation. 21: 1791-802. PMID 22776064 DOI: 10.3727/096368912X653011  0.27
1990 Turco E, Manfras BJ, Ge L, Rudert WA, Trucco M. The X boxes from promoters of HLA class II B genes at different loci do not compete for nuclear protein-specific binding Immunogenetics. 32: 117-128. PMID 1975797 DOI: 10.1007/Bf00210449  0.269
1994 Weidmann E, Trucco M, Whiteside TL. Relevance of the T cell receptor for immunotherapy of cancer Cancer Immunology, Immunotherapy. 39: 1-14. PMID 8044821 DOI: 10.1007/Bf01517174  0.269
1995 Nimgaonkar VL, Rudert WA, Zhang XR, Tsoi WF, Trucco M, Saha N. Further evidence for an association between schizophrenia and the HLA DQB1 gene locus Schizophrenia Research. 18: 43-49. PMID 8929760 DOI: 10.1016/0920-9964(95)00023-2  0.267
2003 Balkundi DR, Ziegler JA, Watchko JF, Craven C, Trucco M. Regulation of FasL/Fas in Human Trophoblasts: Possible Implications for Chorioamnionitis Biology of Reproduction. 69: 718-724. PMID 12700199 DOI: 10.1095/Biolreprod.102.013102  0.262
1993 Nimgaonkar VL, Ganguli R, Rudert WA, Vavassori C, Rabin BS, Trucco M. A negative association of schizophrenia with an allele of the HLA DQB1 gene among African-Americans Schizophrenia Research. 8: 199-209. PMID 8435383 DOI: 10.1016/0920-9964(93)90018-E  0.26
2001 Chowdari KV, Xu K, Zhang F, Ma C, Li T, Yong Xie B, Wood J, Trucco M, Tsoi WF, Saha N, Rudert WA, Nimgaonkar VL. Immune related genetic polymorphisms and schizophrenia among the Chinese Human Immunology. 62: 714-724. PMID 11423178 DOI: 10.1016/S0198-8859(01)00256-7  0.259
2013 Cooper DK, Bottino R, Satyananda V, Wijkstrom M, Trucco M. Toward clinical islet xenotransplantation - are revisions to the IXA guidelines warranted? Xenotransplantation. 20: 68-74. PMID 23320741 DOI: 10.1111/Xen.12015  0.257
2001 Jordan JA, Lowery D, Trucco M. TaqMan-based detection of Trichomonas vaginalis DNA from female genital specimens. Journal of Clinical Microbiology. 39: 3819-22. PMID 11682492 DOI: 10.1128/Jcm.39.11.3819-3822.2001  0.256
2004 Trucco M. Stem cells and diabetes. Pediatric Diabetes. 5: 2-4. PMID 15601368 DOI: 10.1111/j.1399-543X.2004.00073.x  0.254
2007 Rudert WA, Trucco M. To be DR8 or not to be DQ8, that is the question. Pediatric Diabetes. 8: 1-4. PMID 17341284 DOI: 10.1111/J.1399-5448.2006.00219.X  0.254
1997 Witchel SF, Lee PA, Suda-Hartman M, Trucco M, Hoffman EP. Evidence for a heterozygote advantage in congenital adrenal hyperplasia due to 21-hydroxylase deficiency. The Journal of Clinical Endocrinology and Metabolism. 82: 2097-2101. PMID 9215278 DOI: 10.1210/Jcem.82.7.4086  0.252
1999 Gandhi CR, Kuddus R, Subbotin VM, Prelich J, Murase N, Rao AS, Nalesnik MA, Watkins SC, DeLeo A, Trucco M, Starzl TE. A fresh look at augmenter of liver regeneration in rats. Hepatology. 29: 1435-1445. PMID 10216127 DOI: 10.1002/Hep.510290522  0.251
2000 Koike C, Friday RP, Nakashima I, Luppi P, Fung JJ, Rao AS, Starzl TE, Trucco M. Isolation of the regulatory regions and genomic organization of the porcine α1,3-galactosyltransferase gene1 Transplantation. 70: 1275-1283. PMID 11087141 DOI: 10.1097/00007890-200011150-00004  0.25
1997 Nimgaonkar VL, Rudert WA, Zhang X, Trucco M, Ganguli R. Negative association of schizophrenia with HLA DQB1*0602: Evidence from a second African-American cohort Schizophrenia Research. 23: 81-86. PMID 9050131 DOI: 10.1016/S0920-9964(96)00086-2  0.249
2012 Haidet J, Cifarelli V, Trucco M, Luppi P. C-peptide reduces pro-inflammatory cytokine secretion in LPS-stimulated U937 monocytes in condition of hyperglycemia. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. 61: 27-35. PMID 21947415 DOI: 10.1007/S00011-011-0384-8  0.248
1995 Siegel SF, Lee PA, Rudert WA, Swinyard M, Trucco M. Phenotype/Genotype correlations in 21-hydroxylase deficiency Adolescent and Pediatric Gynecology. 8: 9-16. DOI: 10.1016/S0932-8610(12)80154-X  0.247
1993 Starzl TE, Demetris AJ, Trucco M, Ricordi C, Murase N, Thomson AW. The Role of Cell Migration and Chimerism in Organ Transplant Acceptance and Tolerance Induction. Transplantation Science. 3: 47-50. PMID 21572595  0.246
2021 Phillips BE, Garciafigueroa Y, Engman C, Liu W, Wang Y, Lakomy RJ, Meng WS, Trucco M, Giannoukakis N. Arrest in the Progression of Type 1 Diabetes at the Mid-Stage of Insulitic Autoimmunity Using an Autoantigen-Decorated All- Retinoic Acid and Transforming Growth Factor Beta-1 Single Microparticle Formulation. Frontiers in Immunology. 12: 586220. PMID 33763059 DOI: 10.3389/fimmu.2021.586220  0.246
2007 Ringquist S, Pecoraro C, Lu Y, Styche A, Rudert WA, Benos PV, Trucco M. Web-based primer design software for genome-scale genotyping by pyrosequencing. Methods in Molecular Biology (Clifton, N.J.). 373: 25-38. PMID 17185755 DOI: 10.1385/1-59745-377-3:25  0.245
1995 Zhang X, Rudert W, Nimgaonkar V, Tsoi W, Trucco M, Saha N. The HLA DQB1 gene locus: Further evidence for an association with schizophrenia Schizophrenia Research. 15: 45. DOI: 10.1016/0920-9964(95)95146-Z  0.242
2005 Ringquist S, Pecoraro C, Gilchrist CM, Styche A, Rudert WA, Benos PV, Trucco M. SOP3v2: web-based selection of oligonucleotide primer trios for genotyping of human and mouse polymorphisms. Nucleic Acids Research. 33: W548-52. PMID 15980532 DOI: 10.1093/Nar/Gki483  0.242
2007 Cifarelli V, Libman IM, Deluca A, Becker D, Trucco M, Luppi P. Increased Expression of Monocyte CD11b (Mac-1) in Overweight Recent-Onset Type 1 Diabetic Children. The Review of Diabetic Studies : Rds. 4: 112-7. PMID 17823696 DOI: 10.1900/RDS.2007.4.112  0.241
1994 Manfras BJ, Rudert WA, Trucco M, Boehm BO. Cloning and characterization of a glutamate transporter cDNA from human brain and pancreas. Biochimica Et Biophysica Acta. 1195: 185-188. PMID 7522567 DOI: 10.1016/0005-2736(94)90026-4  0.24
2011 Selivanov VA, Votyakova TV, Pivtoraiko VN, Zeak J, Sukhomlin T, Trucco M, Roca J, Cascante M. Reactive oxygen species production by forward and reverse electron fluxes in the mitochondrial respiratory chain. Plos Computational Biology. 7: e1001115. PMID 21483483 DOI: 10.1371/Journal.Pcbi.1001115  0.24
2005 Corcoran DL, Feingold E, Dominick J, Wright M, Harnaha J, Trucco M, Giannoukakis N, Benos PV. Footer: a quantitative comparative genomics method for efficient recognition of cis-regulatory elements. Genome Research. 15: 840-7. PMID 15930494 DOI: 10.1101/Gr.2952005  0.237
1995 Kocova M, Witchel SF, Nalesnik M, Lee PA, Dickman PS, MacGillivray MH, Reiter EO, Trucco G, Trucco M. Y chromosomal sequences identified in gonadal tissue of two 45,X patients with turner syndrome Endocrine Pathology. 6: 311-322. DOI: 10.1007/Bf02738731  0.235
2016 Tajima A, Pradhan I, Trucco M, Fan Y. Restoration of Thymus Function with Bioengineered Thymus Organoids. Current Stem Cell Reports. 2: 128-139. PMID 27529056 DOI: 10.1007/s40778-016-0040-x  0.235
2009 Fan Y, Menon RK, Cohen P, Hwang D, Clemens T, DiGirolamo DJ, Kopchick JJ, Le Roith D, Trucco M, Sperling MA. Liver-specific deletion of the growth hormone receptor reveals essential role of growth hormone signaling in hepatic lipid metabolism. The Journal of Biological Chemistry. 284: 19937-44. PMID 19460757 DOI: 10.1074/Jbc.M109.014308  0.235
1996 Jordan J, Faas S, Braun E, Trucco M. Exonuclease-released Fluorescence Detection of Human Parvovirus B19 DNA. Molecular Diagnosis. 1: 321-328. DOI: 10.1016/S1084-8592(96)70015-2  0.234
2002 Alexander AM, Nichol L, Ringquist S, Styche A, Rudert WA, Trucco M. Pyrosequencing sheds light on HLA genotyping Human Immunology. 63. DOI: 10.1016/S0198-8859(02)00655-9  0.234
1993 Kocova M, Siegel SF, Wenger SL, Lee PA, Trucco M. Detection of Y chromosome sequences in Turner's syndrome by Southern blot analysis of amplified DNA. Lancet (London, England). 342: 140-3. PMID 8101256 DOI: 10.1016/0140-6736(93)91345-M  0.234
2003 Giannoukakis N, Trucco M. Gene therapy technology applied to disorders of glucose metabolism: promise, achievements, and prospects. Biotechniques. 35: 122-145. PMID 12866413 DOI: 10.2144/03351Rv01  0.234
2009 Rudert WA, Trucco M. Breakthrough in diabetes therapy ... Just around the corner? The Review of Diabetic Studies : Rds. 6: 76-80. PMID 19806236 DOI: 10.1900/RDS.2009.6.76  0.234
2005 Alexander AM, Pecoraro C, Styche A, Rudert WA, Benos PV, Ringquist S, Trucco M. SOP3: a web-based tool for selection of oligonucleotide primers for single nucleotide polymorphism analysis by Pyrosequencing. Biotechniques. 38: 87-94. PMID 15679090 DOI: 10.2144/05381Rr01  0.234
2015 Engman C, Wen Y, Meng WS, Bottino R, Trucco M, Giannoukakis N. Generation of antigen-specific Foxp3+ regulatory T-cells in vivo following administration of diabetes-reversing tolerogenic microspheres does not require provision of antigen in the formulation. Clinical Immunology (Orlando, Fla.). 160: 103-23. PMID 25773782 DOI: 10.1016/j.clim.2015.03.004  0.231
2009 Trucco M. Gene-environment interaction in type 1 diabetes mellitus. Endocrinología Y NutricióN : ÓRgano De La Sociedad EspañOla De Endocrinología Y NutricióN. 56: 56-9. PMID 20629235  0.231
2009 Trucco M. Gene-environment interaction in type 1 diabetes mellitus. Endocrinologia Y Nutricion : Organo De La Sociedad Espanola De Endocrinologia Y Nutricion. 56: 56-59. PMID 20542231 DOI: 10.1016/S1575-0922(09)73521-1  0.231
1993 Kocova M, Siegel SF, Rudert WA, Trucco M. Presence Of The Sry Gene In Disorders Of Sexual Differentiation Pediatric Research. 33. DOI: 10.1203/00006450-199305001-00090  0.228
1996 Witchel SS, Lee PA, Trucco M. Who is a carrier? Detection of unsuspected mutations in 21-hydroxylase deficiency. American Journal of Medical Genetics. 61: 2-9. PMID 8741909 DOI: 10.1002/(Sici)1096-8628(19960102)61:1<2::Aid-Ajmg1>3.0.Co;2-1  0.228
1994 Murr J, Martell J, Thompson WO, Harner CD, Jamison JP, Randhawa P, Trucco M, Saidman SL. HLA antibody response to fresh bone-patellar tendon-bone allograft aCL reconstruction Human Immunology. 40: 132. DOI: 10.1016/0198-8859(94)91921-6  0.228
2002 Pietropaolo M, Giannoukakis N, Trucco M. Cellular environment and freedom of gene expression. Nature Immunology. 3: 335-335. PMID 11919570 DOI: 10.1038/Ni0402-335A  0.227
2009 Selivanov VA, Votyakova TV, Zeak JA, Trucco M, Roca J, Cascante M. Bistability of mitochondrial respiration underlies paradoxical reactive oxygen species generation induced by anoxia. Plos Computational Biology. 5: e1000619. PMID 20041200 DOI: 10.1371/Journal.Pcbi.1000619  0.226
2008 Zhang L, Perdomo G, Kim DH, Qu S, Ringquist S, Trucco M, Dong HH. Proteomic analysis of fructose-induced fatty liver in hamsters. Metabolism: Clinical and Experimental. 57: 1115-24. PMID 18640390 DOI: 10.1016/J.Metabol.2008.03.017  0.224
1995 Kocova M, Siegel SF, Wenger SL, Lee PA, Nalesnik M, Trucco M. Detection of Y chromosome sequences in a 45,X/46,XXq--patient by Southern blot analysis of PCR-amplified DNA and fluorescent in situ hybridization (FISH). American Journal of Medical Genetics. 55: 483-8. PMID 7762591 DOI: 10.1002/Ajmg.1320550418  0.223
2001 Koike C, Friday R, Fung JJ, Starzl TE, Trucco M. Comparison of the regulatory regions of the α1,3galactosyltransferase gene between murine and porcine species Transplantation Proceedings. 33: 710-711. PMID 11267031 DOI: 10.1016/S0041-1345(00)02216-8  0.22
1991 Giorda R, Peakman M, Tan KC, Vergani D, Trucco M. Glutamic acid decarboxylase expression in islets and brain The Lancet. 338: 1469-1470. PMID 1683463 DOI: 10.1016/0140-6736(91)92781-V  0.22
1991 Drash AL, Lipton RB, Dorman JS, Becker DJ, LaPorte RE, Orchard TJ, Riley WJ, Trucco M, Kuller LH. The interface between epidemiology and molecular biology in the search for the causes of insulin-dependent diabetes mellitus. Annals of Medicine. 23: 463-71. PMID 1930943 DOI: 10.3109/07853899109148090  0.22
2012 Selivanov VA, Cascante M, Friedman M, Schumaker MF, Trucco M, Votyakova TV. Multistationary and oscillatory modes of free radicals generation by the mitochondrial respiratory chain revealed by a bifurcation analysis. Plos Computational Biology. 8: e1002700. PMID 23028295 DOI: 10.1371/Journal.Pcbi.1002700  0.22
1992 Trucco M. Molecular mechanisms involved in the etiology and pathogenesis of autoimmune diseases. Journal of Molecular Medicine. 70: 756-765. PMID 1450629 DOI: 10.1007/Bf00180744  0.219
2008 Selivanov VA, Zeak JA, Roca J, Cascante M, Trucco M, Votyakova TV. The role of external and matrix pH in mitochondrial reactive oxygen species generation. The Journal of Biological Chemistry. 283: 29292-300. PMID 18687689 DOI: 10.1074/Jbc.M801019200  0.218
1997 Rudert WA, Braun ER, Faas SJ, Menon R, Jaquins-Gerstl A, Trucco M. Double-labeled fluorescent probes for 5' nuclease assays: purification and performance evaluation. Biotechniques. 22: 1140-5. PMID 9187765 DOI: 10.2144/97226Rr02  0.215
1991 Giorda R, Turco E, Trucco M. Full length β chain cDNAs of DQw9 and DQw8 molecules encode proteins that differ only at amino acid 57 Immunogenetics. 33: 404-408. PMID 2050393 DOI: 10.1007/Bf00216702  0.215
1998 Dickinson EC, Gorga JC, Garrett M, Tuncer R, Boyle P, Watkins SC, Alber SM, Parizhskaya M, Trucco M, Rowe MI, Ford HR. Immunoglobulin A supplementation abrogates bacterial translocation and preserves the architecture of the intestinal epithelium. Surgery. 124: 284-90. PMID 9706150 DOI: 10.1016/S0039-6060(98)70132-1  0.215
1993 Hong HK, Giorda R, Trucco M, Chakravarti A. Dinucleotide repeat polymorphism at the DXS1146 locus. Human Molecular Genetics. 2: 1078. PMID 8364552 DOI: 10.1093/Hmg/2.7.1078  0.215
2000 Tian H, Jaquins-Gerstl A, Munro N, Trucco M, Brody LC, Landers JP. Single-strand conformation polymorphism analysis by capillary and microchip electrophoresis: a fast, simple method for detection of common mutations in BRCA1 and BRCA2. Genomics. 63: 25-34. PMID 10662541 DOI: 10.1006/Geno.1999.6067  0.215
1993 Hong HK, Giorda R, Yu LM, Trucco M, Chakravarti A. Microsatellite repeat polymorphism at the D13S197 locus. Human Molecular Genetics. 2: 337. PMID 8499932 DOI: 10.1093/Hmg/2.3.337-A  0.213
2015 Johnston PC, Bottino R, Trucco M, Lin YK, Walsh RM, Stevens TK, Bena J, Hatipoglu BA. Author Response to Letter by Delibasi T., et al. The Journal of Clinical Endocrinology and Metabolism. 100: L62. PMID 26151405 DOI: 10.1210/Jc.2015-2293  0.213
1993 Hong HK, Giorda R, Trucco M, Chakravarti A. Dinucleotide repeat polymorphisms at the D13S192 and D13S193 loci. Human Molecular Genetics. 2: 86. PMID 8490629 DOI: 10.1093/Hmg/2.1.86  0.212
1997 Shpilberg O, Dorman JS, Ferrell RE, Trucco M, Shahar A, Kuller LH. The next stage: molecular epidemiology. Journal of Clinical Epidemiology. 50: 633-8. PMID 9250260 DOI: 10.1016/S0895-4356(97)00052-8  0.211
1988 Dorman JS, Trucco M, LaPorte RE, Kuller LH. Family studies: The key to understanding the genetic and environmental etiology of chronic disease? Genetic Epidemiology. 5: 305-310. PMID 3215505 DOI: 10.1002/Gepi.1370050502  0.207
1994 Kocova M, Siegel SF, Nalesnick M, Trucco M. Detection of Y-chromosome sequences in gonadal tissue of patients with Turner's syndrome (45,X) The New England Journal of Medicine. 331: 682-3. PMID 8052288 DOI: 10.1056/Nejm199409083311021  0.205
2016 Lord P, Spiering R, Aguillon JC, Anderson AE, Appel S, Benitez-Ribas D, Ten Brinke A, Broere F, Cools N, Cuturi MC, Diboll J, Geissler EK, Giannoukakis N, Gregori S, van Ham SM, ... ... Trucco M, et al. Minimum information about tolerogenic antigen-presenting cells (MITAP): a first step towards reproducibility and standardisation of cellular therapies. Peerj. 4: e2300. PMID 27635311 DOI: 10.7717/Peerj.2300  0.205
2015 Szabat M, Page MM, Panzhinskiy E, Skovsø S, Mojibian M, Fernandez-Tajes J, Bruin JE, Bround MJ, Lee JT, Xu EE, Taghizadeh F, O'Dwyer S, van de Bunt M, Moon KM, Sinha S, ... ... Trucco M, et al. Reduced Insulin Production Relieves Endoplasmic Reticulum Stress and Induces β Cell Proliferation. Cell Metabolism. PMID 26626461 DOI: 10.1016/J.Cmet.2015.10.016  0.205
2009 Haidet J, Cifarelli V, Trucco M, Luppi P. Anti-inflammatory properties of C-Peptide. The Review of Diabetic Studies : Rds. 6: 168-79. PMID 20039006 DOI: 10.1900/RDS.2009.6.168  0.204
1990 Trucco M, Dorman JS, Todd JA, McDevitt HO, Morel P. A relative risk of 107 for IDDM is conferred to non-Asp 57 homozygotes Journal of Autoimmunity. 3: 99-100. DOI: 10.1016/0896-8411(90)90118-C  0.204
1993 Kocova M, Trucco M, Konstantinova M, Dorman JS. A cold spot of IDDM incidence in Europe. Macedonia. Diabetes Care. 16: 1236-40. PMID 8404426 DOI: 10.2337/Diacare.16.9.1236  0.202
1990 Rudert WA, Trucco M. DNA polymers of protein binding sequences generated by PCR Nucleic Acids Research. 18: 6460-6460. PMID 2243810 DOI: 10.1093/Nar/18.21.6460  0.2
1992 Rudert WA, Trucco M. Rapid detection of sequence variations using polymers of specific oligonucleotides. Nucleic Acids Research. 20: 1146-1146. PMID 1549484 DOI: 10.1093/Nar/20.5.1146  0.199
2013 Wilson AL, Swerdlow SH, Przybylski GK, Surti U, Choi JK, Campo E, Trucco MM, Van Oss SB, Felgar RE. Intestinal γδ T-cell lymphomas are most frequently of type II enteropathy-associated T-cell type. Human Pathology. 44: 1131-45. PMID 23332928 DOI: 10.1016/j.humpath.2012.10.002  0.195
1996 Sachs DH, Starzl TE, Demetris AJ, Murase N, Trucco M, Thomson AW, Rao AS. Response to Wood and Sachs Immunology Today. 17: 588. DOI: 10.1016/S0167-5699(96)90143-7  0.192
1992 Trucco M. To be or not to be Asp 57, that is the question. Diabetes Care. 15: 705-15. PMID 1355423 DOI: 10.2337/Diacare.15.5.705  0.191
1979 Stocker JW, Garotta G, Hausmann B, Trucco M, Ceppellini R. Separation of human cells bearing HLA-DR antigens using a monoclonal antibody rosetting method. Tissue Antigens. 13: 212-22. PMID 375463 DOI: 10.1111/J.1399-0039.1979.TB00786.X  0.19
1996 Santiago A, Gonzalez L, Bull R, Dorman J, Trucco M, Serrano-Rios M, Frazer-Llado T. Frequency of the DQβ1* and DQα1* genotype in Puerto Ricans (PR) Human Immunology. 47: 62. DOI: 10.1016/0198-8859(96)85026-9  0.189
1997 Nimgaonkar V, Rudert W, Zhang F, Gentry K, Barron Y, Snider A, Zhang X, Ganguli R, Trucco M. Association between schizophrenia and markers on chromosome 6p21 Schizophrenia Research. 24: 51. DOI: 10.1016/S0920-9964(97)82146-9  0.186
1999 Müller J, Ritzén EM, Ivarsson S, Meyts ER, Norjavaara E, Skakkebæk NE, Misao R, Iwagaki S, Fujimoto J, Hung W, Sun W, Tamaya T, Mohn A, Fahlbusch R, Dörr HG, ... ... Trucco M, et al. Revised Guidelines for Neonatal Screening Programmes for Primary Congenital Hypothyroidism Hormone Research in Paediatrics. 52: 49-52. PMID 10640901 DOI: 10.1159/000023433  0.184
1994 Patijn GA, Valdivia LA, Pan F, Frye C, Giorda R, Trucco M, Fung JJ. A new xenogeneic radiation chimera (hamster-to-rat). Transplantation. 57: 1528-1532. PMID 8197620 DOI: 10.1097/00007890-199405270-00025  0.181
1981 Trucco M, de Petris S, Garotta G, Ceppellini R. Quantitative analysis of cell surface HLA structures by means of monoclonal antibodies. Human Immunology. 1: 233-43. PMID 6266984 DOI: 10.1016/0198-8859(80)90018-X  0.18
2015 Garciafigueroa Y, Trucco M, Giannoukakis N. A brief glimpse over the horizon for type 1 diabetes nanotherapeutics. Clinical Immunology (Orlando, Fla.). 160: 36-45. PMID 25817545 DOI: 10.1016/j.clim.2015.03.016  0.179
1992 Gavard JA, Dorman JS, LaPorte RE, Orchard TJ, Drash AL, Trucco MM, Kelsey SF, Kostraba JN, Becker DJ. Sex differences in secondary attack rate of IDDM to siblings of probands through older ages. Pittsburgh Etiology of IDDM Study. Diabetes Care. 15: 559-61. PMID 1499479 DOI: 10.2337/Diacare.15.4.559  0.173
2022 Phillips BE, Lantier L, Engman C, Garciafigueroa Y, Singhi A, Trucco M, Mantzoros C, Wasserman D, Giannoukakis N. Improvement in insulin sensitivity and prevention of high fat diet-induced liver pathology using a CXCR2 antagonist. Cardiovascular Diabetology. 21: 130. PMID 35831885 DOI: 10.1186/s12933-022-01564-y  0.17
1996 Shapiro R, Rao AS, Fontes P, Zeevi A, Jordan M, Scantlebury VP, Vivas C, Gritsch HA, Corry RJ, Egidi F, Rugeles MT, Rilo H, Aitouche A, Demetris AJ, Rosner G, ... Trucco M, et al. Kidney/Bone Marrow Transplantation. Dialysis & Transplantation. 25: 282-287. PMID 21625353  0.15
1981 Ceppellini R, Garotta G, Malavasi F, Trucco M. Modulation of expression of HLA components at the cell surface induced by anti-beta 2m reagents. Tissue Antigens. 17: 28-36. PMID 7018011 DOI: 10.1111/J.1399-0039.1981.TB00663.X  0.146
1991 Tong J, Hsia S, Nghiem D, Cottington E, Rudent W, Trucco M. HLA DQB genotype compatibility and renal graft survival Human Immunology. 32: 106. DOI: 10.1016/0198-8859(91)90314-Y  0.142
2006 Trucco M. Is Facilitating Pancreatic Beta Cell Regeneration a Valid Option for Clinical Therapy? Cell Transplantation. 15: 75-84. PMID 28863766 DOI: 10.3727/000000006783982322  0.141
2008 Luca D, Ringquist S, Klei L, Lee AB, Gieger C, Wichmann HE, Schreiber S, Krawczak M, Lu Y, Styche A, Devlin B, Roeder K, Trucco M. On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. American Journal of Human Genetics. 82: 453-63. PMID 18252225 DOI: 10.1016/J.Ajhg.2007.11.003  0.137
2012 Achkar JP, Klei L, de Bakker PI, Bellone G, Rebert N, Scott R, Lu Y, Regueiro M, Brzezinski A, Kamboh MI, Fiocchi C, Devlin B, Trucco M, Ringquist S, Roeder K, et al. Amino acid position 11 of HLA-DRβ1 is a major determinant of chromosome 6p association with ulcerative colitis. Genes and Immunity. 13: 245-52. PMID 22170232 DOI: 10.1038/Gene.2011.79  0.129
1993 Starzl TE, Demetris AJ, Trucco M. HLA matching and the point system. Clinical Transplantation. 7: 353-356. PMID 21151745  0.126
2010 Wu J, Devlin B, Ringquist S, Trucco M, Roeder K. Screen and clean: a tool for identifying interactions in genome-wide association studies. Genetic Epidemiology. 34: 275-85. PMID 20088021 DOI: 10.1002/Gepi.20459  0.117
2010 Trucco M. Beta-cell regeneration: from science fiction to challenging reality. Pediatric Diabetes. 11: 292-5. PMID 20646239 DOI: 10.1111/j.1399-5448.2010.00704.x  0.113
2021 Naples R, Perlmutter BC, Thomas JD, McMichael J, Bottino R, Solomina J, Trucco M, Augustin T, Simon R, Walsh RM. Clinical Significance of Postoperative Antibiotic Treatment for Positive Islet Cultures After Total Pancreatectomy With Islet Autotransplantation. Pancreas. 50: 1000-1006. PMID 34629454 DOI: 10.1097/MPA.0000000000001874  0.113
2010 Coudriet GM, He J, Trucco M, Mars WM, Piganelli JD. Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases. Plos One. 5: e15384. PMID 21072211 DOI: 10.1371/Journal.Pone.0015384  0.103
1978 Trucco MM, Stocker JW, Ceppellini R. Monoclonal antibodies to human lymphocyte membrane antigens. Current Topics in Microbiology and Immunology. 81: 66-9. PMID 688762 DOI: 10.1007/978-3-642-67448-8_11  0.093
1980 Trucco MM, Garotta G, Stocker JW, Ceppellini R. Murine monoclonal antibodies against HLA structures. Immunological Reviews. 47: 219-52. PMID 95014 DOI: 10.1111/j.1600-065X.1979.tb00295.x  0.088
2020 Kocova M, Witchel SF, Nalesnik M, Lee PA, Dickman PS, MacGillivray MH, Reiter EO, Trucco G, Trucco M. Y Chromosomal Sequences Identified in Gonadal Tissue of Two 45,X Patients with Turner Syndrome. Endocrine Pathology. 6: 311-322. PMID 12114813 DOI: 10.1007/BF02738731  0.084
2013 Thornton KA, Chen AR, Trucco MM, Shah P, Wilky BA, Gul N, Carrera-Haro MA, Ferreira MF, Shafique U, Powell JD, Meyer CF, Loeb DM. A dose-finding study of temsirolimus and liposomal doxorubicin for patients with recurrent and refractory bone and soft tissue sarcoma. International Journal of Cancer. Journal International Du Cancer. 133: 997-1005. PMID 23382028 DOI: 10.1002/ijc.28083  0.08
2010 Crossett A, Kent BP, Klei L, Ringquist S, Trucco M, Roeder K, Devlin B. Using ancestry matching to combine family-based and unrelated samples for genome-wide association studies. Statistics in Medicine. 29: 2932-45. PMID 20862653 DOI: 10.1002/Sim.4057  0.061
2002 Luppi P, Haluszczak C, Betters D, Richard CAH, Trucco M, DeLoia JA. Monocytes are progressively activated in the circulation of pregnant women Journal of Leukocyte Biology. 72: 874-884. PMID 12429709  0.024
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