Katharine A. Whartenby - Publications

Affiliations: 
Cellular and Molecualr Medicine Johns Hopkins University, Baltimore, MD 
Area:
Molecular Biology, Immunology, Cell Biology

36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chamling X, Kallman A, Fang W, Berlinicke CA, Mertz JL, Devkota P, Pantoja IEM, Smith MD, Ji Z, Chang C, Kaushik A, Chen L, Whartenby KA, Calabresi PA, Mao HQ, et al. Single-cell transcriptomic reveals molecular diversity and developmental heterogeneity of human stem cell-derived oligodendrocyte lineage cells. Nature Communications. 12: 652. PMID 33510160 DOI: 10.1038/s41467-021-20892-3  0.326
2020 Morales Pantoja IE, Smith MD, Rajbhandari L, Cheng L, Gao Y, Mahairaki V, Venkatesan A, Calabresi PA, Fitzgerald KC, Whartenby KA. iPSCs from people with MS can differentiate into oligodendrocytes in a homeostatic but not an inflammatory milieu. Plos One. 15: e0233980. PMID 32511247 DOI: 10.1371/Journal.Pone.0233980  0.401
2019 Glenn JD, Pantoja IM, Caturegli P, Whartenby KA. MYMD-1, a novel alkaloid compound, ameliorates the course of experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. 339: 577115. PMID 31778849 DOI: 10.1016/J.Jneuroim.2019.577115  0.398
2019 Gonzalez Cardona J, Smith MD, Wang J, Kirby L, Schott JT, Davidson T, Karnell JL, Whartenby KA, Calabresi PA. Quetiapine has an additive effect to triiodothyronine in inducing differentiation of oligodendrocyte precursor cells through induction of cholesterol biosynthesis. Plos One. 14: e0221747. PMID 31490950 DOI: 10.1371/Journal.Pone.0221747  0.365
2019 Jin J, Smith MD, Kersbergen CJ, Kam TI, Viswanathan M, Martin K, Dawson TM, Dawson VL, Zack DJ, Whartenby K, Calabresi PA. Glial pathology and retinal neurotoxicity in the anterior visual pathway in experimental autoimmune encephalomyelitis. Acta Neuropathologica Communications. 7: 125. PMID 31366377 DOI: 10.1186/S40478-019-0767-6  0.335
2019 Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, et al. Early complement genes are associated with visual system degeneration in multiple sclerosis. Brain : a Journal of Neurology. PMID 31289819 DOI: 10.1093/Brain/Awz188  0.3
2019 Glenn JD, Liu C, Whartenby KA. Frontline Science: Induction of experimental autoimmune encephalomyelitis mobilizes Th17-promoting myeloid derived suppressor cells to the lung. Journal of Leukocyte Biology. PMID 30762897 DOI: 10.1002/Jlb.4Hi0818-335R  0.494
2017 Glenn JD, Xue P, Whartenby KA. Gemcitabine directly inhibits effector CD4 T cell activation and prevents experimental autoimmune encephalomyelitis. Journal of Neuroimmunology. PMID 29274729 DOI: 10.1016/J.Jneuroim.2017.12.002  0.491
2017 Glenn JD, Smith MD, Xue P, Chan-Li Y, Collins S, Calabresi PA, Horton MR, Whartenby KA. CNS-targeted autoimmunity leads to increased influenza mortality in mice. The Journal of Experimental Medicine. PMID 28057805 DOI: 10.1084/Jem.20160517  0.372
2015 Glenn JD, Smith MD, Kirby LA, Baxi EG, Whartenby KA. Disparate Effects of Mesenchymal Stem Cells in Experimental Autoimmune Encephalomyelitis and Cuprizone-Induced Demyelination. Plos One. 10: e0139008. PMID 26407166 DOI: 10.1371/Journal.Pone.0139008  0.518
2014 Glenn JD, Whartenby KA. Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy. World Journal of Stem Cells. 6: 526-39. PMID 25426250 DOI: 10.4252/Wjsc.V6.I5.526  0.408
2014 Glenn JD, Smith MD, Calabresi PA, Whartenby KA. Mesenchymal stem cells differentially modulate effector CD8+ T cell subsets and exacerbate experimental autoimmune encephalomyelitis. Stem Cells (Dayton, Ohio). 32: 2744-55. PMID 24911892 DOI: 10.1002/Stem.1755  0.514
2013 Rosenzweig JM, Glenn JD, Calabresi PA, Whartenby KA. KLF4 modulates expression of IL-6 in dendritic cells via both promoter activation and epigenetic modification. The Journal of Biological Chemistry. 288: 23868-74. PMID 23846700 DOI: 10.1074/Jbc.M113.479576  0.336
2013 Hu L, Wang T, Gocke AR, Nath A, Zhang H, Margolick JB, Whartenby KA, Calabresi PA. Blockade of Kv1.3 potassium channels inhibits differentiation and granzyme B secretion of human CD8+ T effector memory lymphocytes. Plos One. 8: e54267. PMID 23382885 DOI: 10.1371/Journal.Pone.0054267  0.488
2012 Gocke AR, Lebson LA, Grishkan IV, Hu L, Nguyen HM, Whartenby KA, Chandy KG, Calabresi PA. Kv1.3 deletion biases T cells toward an immunoregulatory phenotype and renders mice resistant to autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5877-86. PMID 22581856 DOI: 10.4049/Jimmunol.1103095  0.52
2012 Hu L, Gocke AR, Knapp E, Rosenzweig JM, Grishkan IV, Baxi EG, Zhang H, Margolick JB, Whartenby KA, Calabresi PA. Functional blockade of the voltage-gated potassium channel Kv1.3 mediates reversion of T effector to central memory lymphocytes through SMAD3/p21cip1 signaling. The Journal of Biological Chemistry. 287: 1261-8. PMID 22110135 DOI: 10.1074/Jbc.M111.296798  0.452
2011 Skarica M, Eckstein C, Whartenby KA, Calabresi PA. Novel mechanisms of immune modulation of natalizumab in multiple sclerosis patients. Journal of Neuroimmunology. 235: 70-6. PMID 21550672 DOI: 10.1016/J.Jneuroim.2011.02.010  0.424
2011 Lebson L, Wang T, Jiang Q, Whartenby KA. Induction of the glucocorticoid induced leucine zipper gene limits the efficacy of dendritic cell vaccines Cancer Gene Therapy. 18: 563-570. PMID 21546924 DOI: 10.1038/Cgt.2011.23  0.311
2010 Lebson L, Gocke A, Rosenzweig J, Alder J, Civin C, Calabresi PA, Whartenby KA. Cutting edge: The transcription factor Kruppel-like factor 4 regulates the differentiation of Th17 cells independently of RORγt. Journal of Immunology (Baltimore, Md. : 1950). 185: 7161-4. PMID 21076063 DOI: 10.4049/Jimmunol.1002750  0.433
2010 DeBoy CA, Rus H, Tegla C, Cudrici C, Jones MV, Pardo CA, Small D, Whartenby KA, Calabresi PA. FLT-3 expression and function on microglia in multiple sclerosis. Experimental and Molecular Pathology. 89: 109-16. PMID 20566414 DOI: 10.1016/J.Yexmp.2010.05.009  0.447
2009 Skarica M, Wang T, McCadden E, Kardian D, Calabresi PA, Small D, Whartenby KA. Signal transduction inhibition of APCs diminishes th17 and Th1 responses in experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 182: 4192-9. PMID 19299717 DOI: 10.4049/Jimmunol.0803631  0.484
2009 Wang T, Jiang Q, Chan C, Gorski KS, McCadden E, Kardian D, Pardoll D, Whartenby KA. Inhibition of activation-induced death of dendritic cells and enhancement of vaccine efficacy via blockade of MINOR. Blood. 113: 2906-13. PMID 19164597 DOI: 10.1182/Blood-2008-08-176354  0.377
2008 Whartenby KA, Small D, Calabresi PA. FLT3 inhibitors for the treatment of autoimmune disease. Expert Opinion On Investigational Drugs. 17: 1685-92. PMID 18922105 DOI: 10.1517/13543784.17.11.1685  0.429
2008 Huang GN, Huso DL, Bouyain S, Tu J, McCorkell KA, May MJ, Zhu Y, Lutz M, Collins S, Dehoff M, Kang S, Whartenby K, Powell J, Leahy D, Worley PF. NFAT binding and regulation of T cell activation by the cytoplasmic scaffolding Homer proteins. Science (New York, N.Y.). 319: 476-81. PMID 18218901 DOI: 10.1126/Science.1151227  0.464
2007 Hu L, Pennington M, Jiang Q, Whartenby KA, Calabresi PA. Characterization of the functional properties of the voltage-gated potassium channel Kv1.3 in human CD4+ T lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 4563-70. PMID 17878353 DOI: 10.4049/Jimmunol.179.7.4563  0.473
2007 Goldberg MV, Maris CH, Hipkiss EL, Flies AS, Zhen L, Tuder RM, Grosso JF, Harris TJ, Getnet D, Whartenby KA, Brockstedt DG, Dubensky TW, Chen L, Pardoll DM, Drake CG. Role of PD-1 and its ligand, B7-H1, in early fate decisions of CD8 T cells. Blood. 110: 186-92. PMID 17392506 DOI: 10.1182/Blood-2006-12-062422  0.38
2007 Pan F, Sun L, Kardian DB, Whartenby KA, Pardoll DM, Liu JO. Feedback inhibition of calcineurin and Ras by a dual inhibitory protein Carabin. Nature. 445: 433-6. PMID 17230191 DOI: 10.1038/Nature05476  0.356
2007 Hu L, Whartenby K, Allie R, Calabresi P. Functional Knockout of Kv1.3 Channels Suppresses Effector Memory Phenotype Acquisition in Dominant Negative Kv1.3-expressing Human CD4+ T Cells Clinical Immunology. 123: S124. DOI: 10.1016/J.Clim.2007.03.532  0.403
2005 Whartenby KA, Calabresi PA, McCadden E, Nguyen B, Kardian D, Wang T, Mosse C, Pardoll DM, Small D. Inhibition of FLT3 signaling targets DCs to ameliorate autoimmune disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 16741-6. PMID 16272221 DOI: 10.1073/Pnas.0506088102  0.478
2004 Freeman SM, Whartenby KA. The role of the mitogen-activated protein kinase cellular signaling pathway in tumor cell survival and apoptosis. Drug News & Perspectives. 17: 237-42. PMID 15334172 DOI: 10.1358/Dnp.2004.17.4.829050  0.314
2004 Jalla S, McCadden E, Wang J, Fuchs EJ, Whartenby KA. Augmentation of Therapeutic Tumor Vaccine Efficacy by Genetic Engineering of CD4+ T Cell Help for Tumor Vaccine-Reactive CD8+ T Cells. Blood. 104: 3175-3175. DOI: 10.1182/Blood.V104.11.3175.3175  0.461
2003 Calabresi PA, Allie R, Mullen KM, Yun SH, Georgantas RW, Whartenby KA. Kinetics of CCR7 expression differ between primary activation and effector memory states of T(H)1 and T(H)2 cells. Journal of Neuroimmunology. 139: 58-65. PMID 12799021 DOI: 10.1016/S0165-5728(03)00127-9  0.465
2003 Cui Y, Kelleher E, Straley E, Fuchs E, Gorski K, Levitsky H, Borrello I, Civin CI, Schoenberger SP, Cheng L, Pardoll DM, Whartenby KA. Immunotherapy of established tumors using bone marrow transplantation with antigen gene--modified hematopoietic stem cells. Nature Medicine. 9: 952-8. PMID 12778137 DOI: 10.1038/Nm882  0.409
2002 Whartenby KA, Straley EE, Kim H, Racke F, Tanavde V, Gorski KS, Cheng L, Pardoll DM, Civin CI. Transduction of donor hematopoietic stem-progenitor cells with Fas ligand enhanced short-term engraftment in a murine model of allogeneic bone marrow transplantation. Blood. 100: 3147-54. PMID 12384412 DOI: 10.1182/Blood-2002-01-0118  0.432
2002 Calabresi PA, Yun SH, Allie R, Whartenby KA. Chemokine receptor expression on MBP-reactive T cells: CXCR6 is a marker of IFNgamma-producing effector cells. Journal of Neuroimmunology. 127: 96-105. PMID 12044980 DOI: 10.1016/S0165-5728(02)00106-6  0.488
2002 Kim H, Whartenby KA, Georgantas RW, Wingard J, Civin CI. Human CD34+ hematopoietic stem/progenitor cells express high levels of FLIP and are resistant to Fas-mediated apoptosis. Stem Cells (Dayton, Ohio). 20: 174-82. PMID 11897874 DOI: 10.1634/Stemcells.20-2-174  0.387
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