Jean-Philippe Gratton - Publications

Affiliations: 
Faculté de médecine Université de Montréal, Montréal, Canada 
Area:
Molecular Biology, Cell Biology

35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Smith TL, Oubaha M, Cagnone G, Boscher C, Kim JS, El Bakkouri Y, Zhang Y, Chidiac R, Corriveau J, Delisle C, Andelfinger GU, Sapieha P, Joyal JS, Gratton JP. eNOS controls angiogenic sprouting and retinal neovascularization through the regulation of endothelial cell polarity. Cellular and Molecular Life Sciences : Cmls. PMID 34971428 DOI: 10.1007/s00018-021-04042-y  0.799
2020 Abu-Thuraia A, Goyette MA, Boulais J, Delliaux C, Apcher C, Schott C, Chidiac R, Bagci H, Thibault MP, Davidson D, Ferron M, Veillette A, Daly RJ, Gingras AC, Gratton JP, et al. AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. Nature Communications. 11: 3586. PMID 32681075 DOI: 10.1038/S41467-020-17415-X  0.381
2020 Gaonac'h-Lovejoy V, Boscher C, Delisle C, Gratton JP. Rap1 is Involved in Angiopoietin-1-Induced Cell-Cell Junction Stabilization and Endothelial Cell Sprouting. Cells. 9. PMID 31936361 DOI: 10.3390/Cells9010155  0.669
2019 Boscher C, Gaonac'h-Lovejoy V, Delisle C, Gratton JP. Polarization and sprouting of endothelial cells by angiopoietin-1 require PAK2 and paxillin-dependent Cdc42 activation. Molecular Biology of the Cell. mbcE18080486. PMID 31141452 DOI: 10.1091/Mbc.E18-08-0486  0.556
2019 Goyette MA, Cusseddu R, Elkholi I, Abu-Thuraia A, El-Hachem N, Haibe-Kains B, Gratton JP, Côté JF. AXL knockdown gene signature reveals a drug repurposing opportunity for a class of antipsychotics to reduce growth and metastasis of triple-negative breast cancer. Oncotarget. 10: 2055-2067. PMID 31007848 DOI: 10.18632/Oncotarget.26725  0.319
2019 Miloudi K, Oubaha M, Ménard C, Dejda A, Guber V, Cagnone G, Wilson AM, Tétreault N, Mawambo G, Binet F, Chidiac R, Delisle C, Buscarlet M, Cerani A, Crespo-Garcia S, ... ... Gratton JP, et al. NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy. Proceedings of the National Academy of Sciences of the United States of America. PMID 30787185 DOI: 10.1073/Pnas.1814711116  0.755
2018 Ouadda ABD, He Y, Calabrese V, Ishii H, Chidiac R, Gratton JP, Roux PP, Lamarche-Vane N. CdGAP/ARHGAP31 is regulated by RSK phosphorylation and binding to 14-3-3β adaptor protein. Oncotarget. 9: 11646-11664. PMID 29545927 DOI: 10.18632/Oncotarget.24126  0.439
2017 Hernández-Vásquez MN, Adame-García SR, Hamoud N, Chidiac R, Reyes-Cruz G, Gratton JP, Côté JF, Vázquez-Prado J. Cell adhesion controlled by adhesion G-protein coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising Intersectins and Elmo/Dock. The Journal of Biological Chemistry. PMID 28600358 DOI: 10.1074/Jbc.M117.780304  0.438
2017 Zhang Y, Chidiac R, Delisle C, Gratton JP. eNOS-dependent S-nitrosylation of β-catenin prevents its association with TCF4 and inhibits proliferation of endothelial cells by Wnt3a. Molecular and Cellular Biology. PMID 28320874 DOI: 10.1128/Mcb.00089-17  0.49
2016 Chidiac R, Zhang Y, Tessier S, Faubert D, Delisle C, Gratton JP. Comparative phosphoproteomics analysis of VEGF and Angiopoietin-1 signaling reveals ZO-1 as a critical regulator of endothelial cell proliferation. Molecular & Cellular Proteomics : McP. PMID 26846344 DOI: 10.1074/Mcp.M115.053298  0.664
2012 Souza CM, Davidson D, Rhee I, Gratton JP, Davis EC, Veillette A. The phosphatase PTP-PEST/PTPN12 regulates endothelial cell migration and adhesion, but not permeability, and controls vascular development and embryonic viability. The Journal of Biological Chemistry. 287: 43180-90. PMID 23105101 DOI: 10.1074/Jbc.M112.387456  0.69
2012 Oubaha M, Lin MI, Margaron Y, Filion D, Price EN, Zon LI, Côté JF, Gratton JP. Formation of a PKCζ/β-catenin complex in endothelial cells promotes angiopoietin-1-induced collective directional migration and angiogenic sprouting. Blood. 120: 3371-81. PMID 22936663 DOI: 10.1182/Blood-2012-03-419721  0.785
2012 Desjardins F, Delisle C, Gratton JP. Modulation of the cochaperone AHA1 regulates heat-shock protein 90 and endothelial NO synthase activation by vascular endothelial growth factor. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 2484-92. PMID 22859491 DOI: 10.1161/Atvbaha.112.256008  0.639
2010 Nouvion AL, Oubaha M, Leblanc S, Davis EC, Jastrow H, Kammerer R, Breton V, Turbide C, Ergun S, Gratton JP, Beauchemin N. CEACAM1: a key regulator of vascular permeability. Journal of Cell Science. 123: 4221-30. PMID 21081647 DOI: 10.1242/Jcs.073635  0.805
2010 Rechka A, Neagoe PE, Gratton JP, Sirois MG. Identification of VEGF receptor-2 tyrosine phosphorylation sites involved in VEGF-mediated endothelial platelet-activating factor synthesis. Canadian Journal of Physiology and Pharmacology. 88: 968-76. PMID 20962896 DOI: 10.1139/y10-064  0.577
2010 Thibeault S, Rautureau Y, Oubaha M, Faubert D, Wilkes BC, Delisle C, Gratton JP. S-nitrosylation of beta-catenin by eNOS-derived NO promotes VEGF-induced endothelial cell permeability. Molecular Cell. 39: 468-76. PMID 20705246 DOI: 10.1016/J.Molcel.2010.07.013  0.793
2010 Daher Z, Boulay PL, Desjardins F, Gratton JP, Claing A. Vascular endothelial growth factor receptor-2 activates ADP-ribosylation factor 1 to promote endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells. The Journal of Biological Chemistry. 285: 24591-9. PMID 20529868 DOI: 10.1074/Jbc.M110.115311  0.732
2009 Oubaha M, Gratton JP. Phosphorylation of endothelial nitric oxide synthase by atypical PKC zeta contributes to angiopoietin-1-dependent inhibition of VEGF-induced endothelial permeability in vitro. Blood. 114: 3343-51. PMID 19564638 DOI: 10.1182/Blood-2008-12-196584  0.806
2009 Michaud MD, Robitaille GA, Gratton JP, Richard DE. Sphingosine-1-phosphate: a novel nonhypoxic activator of hypoxia-inducible factor-1 in vascular cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 902-8. PMID 19423865 DOI: 10.1161/Atvbaha.109.185280  0.524
2009 Chabot C, Spring K, Gratton JP, Elchebly M, Royal I. New role for the protein tyrosine phosphatase DEP-1 in Akt activation and endothelial cell survival. Molecular and Cellular Biology. 29: 241-53. PMID 18936167 DOI: 10.1128/Mcb.01374-08  0.675
2007 Duval M, Le Boeuf F, Huot J, Gratton JP. Src-mediated phosphorylation of Hsp90 in response to vascular endothelial growth factor (VEGF) is required for VEGF receptor-2 signaling to endothelial NO synthase. Molecular Biology of the Cell. 18: 4659-68. PMID 17855507 DOI: 10.1091/Mbc.E07-05-0467  0.704
2007 Bernatchez PN, Acevedo L, Fernandez-Hernando C, Murata T, Chalouni C, Kim J, Erdjument-Bromage H, Shah V, Gratton JP, McNally EM, Tempst P, Sessa WC. Myoferlin regulates vascular endothelial growth factor receptor-2 stability and function. The Journal of Biological Chemistry. 282: 30745-53. PMID 17702744 DOI: 10.1074/Jbc.M704798200  0.6
2007 Blanes MG, Oubaha M, Rautureau Y, Gratton JP. Phosphorylation of tyrosine 801 of vascular endothelial growth factor receptor-2 is necessary for Akt-dependent endothelial nitric-oxide synthase activation and nitric oxide release from endothelial cells. The Journal of Biological Chemistry. 282: 10660-9. PMID 17303569 DOI: 10.1074/Jbc.M609048200  0.799
2006 Gobeil F, Zhu T, Brault S, Geha A, Vazquez-Tello A, Fortier A, Barbaz D, Checchin D, Hou X, Nader M, Bkaily G, Gratton JP, Heveker N, Ribeiro-da-Silva A, Peri K, et al. Nitric oxide signaling via nuclearized endothelial nitric-oxide synthase modulates expression of the immediate early genes iNOS and mPGES-1. The Journal of Biological Chemistry. 281: 16058-67. PMID 16574649 DOI: 10.1074/Jbc.M602219200  0.502
2006 Roviezzo F, Bucci M, Delisle C, Brancaleone V, Di Lorenzo A, Mayo IP, Fiorucci S, Fontana A, Gratton JP, Cirino G. Essential requirement for sphingosine kinase activity in eNOS-dependent NO release and vasorelaxation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 340-2. PMID 16322129 DOI: 10.1096/Fj.05-4647Fje  0.426
2004 Gratton JP, Bernatchez P, Sessa WC. Caveolae and caveolins in the cardiovascular system. Circulation Research. 94: 1408-17. PMID 15192036 DOI: 10.1161/01.Res.0000129178.56294.17  0.392
2004 Duval M, Bédard-Goulet S, Delisle C, Gratton J. IMPLICATION OF THE UBIQUITIN-PROTEASOME PATHWAY IN THE VEGF-DEPENDENT DOWN-REGULATION OF VEGFR-2 IN ENDOTHELIAL CELLS Cardiovascular Pathology. 13: 46. DOI: 10.1016/J.Carpath.2004.03.132  0.693
2003 Harfouche R, Gratton JP, Yancopoulos GD, Noseda M, Karsan A, Hussain SNA. Angiopoietin-1 activates both anti- and proapoptotic mitogen-activated protein kinases The Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1523-1525. PMID 12824293 DOI: 10.1096/Fj.02-0698Fje  0.512
2003 Duval M, Bédard-Goulet S, Delisle C, Gratton JP. Vascular endothelial growth factor-dependent down-regulation of Flk-1/KDR involves Cbl-mediated ubiquitination. Consequences on nitric oxide production from endothelial cells. The Journal of Biological Chemistry. 278: 20091-7. PMID 12649282 DOI: 10.1074/Jbc.M301410200  0.733
2003 Gratton JP, Yu J, Griffith JW, Babbitt RW, Scotland RS, Hickey R, Giordano FJ, Sessa WC. Cell-permeable peptides improve cellular uptake and therapeutic gene delivery of replication-deficient viruses in cells and in vivo. Nature Medicine. 9: 357-62. PMID 12598894 DOI: 10.1038/Nm835  0.335
2002 Iwakiri Y, Tsai MH, McCabe TJ, Gratton JP, Fulton D, Groszmann RJ, Sessa WC. Phosphorylation of eNOS initiates excessive NO production in early phases of portal hypertension. American Journal of Physiology. Heart and Circulatory Physiology. 282: H2084-90. PMID 12003815 DOI: 10.1152/Ajpheart.00675.2001  0.303
2002 Scotland RS, Morales-Ruiz M, Chen Y, Yu J, Rudic RD, Fulton D, Gratton JP, Sessa WC. Functional reconstitution of endothelial nitric oxide synthase reveals the importance of serine 1179 in endothelium-dependent vasomotion. Circulation Research. 90: 904-10. PMID 11988492 DOI: 10.1161/01.Res.0000016506.04193.96  0.565
2002 Fulton D, Fontana J, Sowa G, Gratton JP, Lin M, Li KX, Michell B, Kemp BE, Rodman D, Sessa WC. Localization of endothelial nitric-oxide synthase phosphorylated on serine 1179 and nitric oxide in Golgi and plasma membrane defines the existence of two pools of active enzyme. The Journal of Biological Chemistry. 277: 4277-84. PMID 11729179 DOI: 10.1074/Jbc.M106302200  0.586
2000 Gratton JP, Fontana J, O'Connor DS, Garcia-Cardena G, McCabe TJ, Sessa WC. Reconstitution of an endothelial nitric-oxide synthase (eNOS), hsp90, and caveolin-1 complex in vitro. Evidence that hsp90 facilitates calmodulin stimulated displacement of eNOS from caveolin-1. The Journal of Biological Chemistry. 275: 22268-72. PMID 10781589 DOI: 10.1074/Jbc.M001644200  0.485
1999 Fulton D, Gratton JP, McCabe TJ, Fontana J, Fujio Y, Walsh K, Franke TF, Papapetropoulos A, Sessa WC. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature. 399: 597-601. PMID 10376602 DOI: 10.1038/21218  0.481
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