Anne-Claude Gingras, Ph.D. - Publications

Affiliations: 
2001 McGill University, Montreal, QC, Canada 
Area:
translational control

203 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Roth JF, Braunschweig U, Wu M, Li JD, Lin ZY, Larsen B, Weatheritt RJ, Gingras AC, Blencowe BJ. Systematic analysis of alternative exon-dependent interactome remodeling reveals multitasking functions of gene regulatory factors. Molecular Cell. 83: 4222-4238.e10. PMID 38065061 DOI: 10.1016/j.molcel.2023.10.034  0.302
2023 Segal D, Maier S, Mastromarco GJ, Qian WW, Nabeel-Shah S, Lee H, Moore G, Lacoste J, Larsen B, Lin ZY, Selvabaskaran A, Liu K, Smibert C, Zhang Z, Greenblatt J, ... ... Gingras AC, et al. A central chaperone-like role for 14-3-3 proteins in human cells. Molecular Cell. 83: 974-993.e15. PMID 36931259 DOI: 10.1016/j.molcel.2023.02.018  0.354
2023 Cormier KW, Larsen B, Gingras AC, Woodgett JR. Interactomes of Glycogen Synthase Kinase-3 Isoforms. Journal of Proteome Research. PMID 36779422 DOI: 10.1021/acs.jproteome.2c00825  0.346
2022 Garcia K, Gingras AC, Harvey KF, Tanas MR. TAZ/YAP fusion proteins: mechanistic insights and therapeutic opportunities. Trends in Cancer. PMID 36096997 DOI: 10.1016/j.trecan.2022.08.002  0.304
2022 Go CD, Knight JDR, Rajasekharan A, Rathod B, Hesketh GG, Abe KT, Youn JY, Samavarchi-Tehrani P, Zhang H, Zhu LY, Popiel E, Lambert JP, Coyaud É, Cheung SWT, Rajendran D, ... ... Gingras AC, et al. Author Correction: A proximity-dependent biotinylation map of a human cell. Nature. PMID 35017685 DOI: 10.1038/s41586-021-04308-2  0.616
2021 Svitkin YV, Gingras AC, Sonenberg N. Membrane-dependent relief of translation elongation arrest on pseudouridine- and N1-methyl-pseudouridine-modified mRNAs. Nucleic Acids Research. PMID 34933339 DOI: 10.1093/nar/gkab1241  0.44
2021 Go CD, Knight JDR, Rajasekharan A, Rathod B, Hesketh GG, Abe KT, Youn JY, Samavarchi-Tehrani P, Zhang H, Zhu LY, Popiel E, Lambert JP, Coyaud É, Cheung SWT, Rajendran D, ... ... Gingras AC, et al. A proximity-dependent biotinylation map of a human cell. Nature. PMID 34079125 DOI: 10.1038/s41586-021-03592-2  0.668
2021 Khan KA, Marineau A, Doyon P, Acevedo M, Durette É, Gingras AC, Servant MJ. TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response. Plos Pathogens. 17: e1009111. PMID 33411856 DOI: 10.1371/journal.ppat.1009111  0.319
2021 Kawashima AT, Wong C, Lordén G, King CC, Lara-Gonzalez P, Desai A, Gingras AC, Newton AC. The PHLPP1 N-Terminal Extension is a Mitotic Cdk1 Substrate and Controls an Interactome Switch. Molecular and Cellular Biology. PMID 33397691 DOI: 10.1128/MCB.00333-20  0.307
2020 Kim SH, Choi JH, Wang P, Go CD, Hesketh GG, Gingras AC, Jafarnejad SM, Sonenberg N. Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation. Molecular Cell. PMID 33340489 DOI: 10.1016/j.molcel.2020.11.036  0.421
2020 Tsatskis Y, Rosenfeld R, Pearson JD, Boswell C, Qu Y, Kim K, Fabian L, Mohammad A, Wang X, Robson MI, Krchma K, Wu J, Gonçalves J, Hodzic D, Wu S, ... ... Gingras AC, et al. The NEMP family supports metazoan fertility and nuclear envelope stiffness. Science Advances. 6: eabb4591. PMID 32923640 DOI: 10.1126/Sciadv.Abb4591  0.325
2020 Tao H, Lambert JP, Yung TM, Zhu M, Hahn NA, Li D, Lau K, Sturgeon K, Puviindran V, Zhang X, Gong W, Chen XX, Anderson G, Garry DJ, Henkelman RM, ... ... Gingras AC, et al. IRX3/5 regulate mitotic chromatid segregation and limb bud shape. Development (Cambridge, England). PMID 32907847 DOI: 10.1242/Dev.180042  0.312
2020 Antonicka H, Lin ZY, Janer A, Aaltonen MJ, Weraarpachai W, Gingras AC, Shoubridge EA. A High-Density Human Mitochondrial Proximity Interaction Network. Cell Metabolism. 32: 479-497.e9. PMID 32877691 DOI: 10.1016/J.Cmet.2020.07.017  0.323
2020 Posternak G, Tang X, Maisonneuve P, Jin T, Lavoie H, Daou S, Orlicky S, Goullet de Rugy T, Caldwell L, Chan K, Aman A, Prakesch M, Poda G, Mader P, Wong C, ... ... Gingras AC, et al. Functional characterization of a PROTAC directed against BRAF mutant V600E. Nature Chemical Biology. PMID 32778845 DOI: 10.1038/S41589-020-0609-7  0.334
2020 Kim DK, Knapp JJ, Kuang D, Chawla A, Cassonnet P, Lee H, Sheykhkarimli D, Samavarchi-Tehrani P, Abdouni H, Rayhan A, Li R, Pogoutse O, Coyaud É, van der Werf S, Demeret C, ... Gingras AC, et al. A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions. G3 (Bethesda, Md.). PMID 32763951 DOI: 10.1534/G3.120.401554  0.643
2020 Abu-Thuraia A, Goyette MA, Boulais J, Delliaux C, Apcher C, Schott C, Chidiac R, Bagci H, Thibault MP, Davidson D, Ferron M, Veillette A, Daly RJ, Gingras AC, Gratton JP, et al. AXL confers cell migration and invasion by hijacking a PEAK1-regulated focal adhesion protein network. Nature Communications. 11: 3586. PMID 32681075 DOI: 10.1038/S41467-020-17415-X  0.407
2020 Maiti P, Antonicka H, Gingras AC, Shoubridge EA, Barrientos A. Human GTPBP5 (MTG2) fuels mitoribosome large subunit maturation by facilitating 16S rRNA methylation. Nucleic Acids Research. PMID 32652011 DOI: 10.1093/Nar/Gkaa592  0.359
2020 Wigington CP, Roy J, Damle NP, Yadav VK, Blikstad C, Resch E, Wong CJ, Mackay DR, Wang JT, Krystkowiak I, Bradburn DA, Tsekitsidou E, Hong SH, Kaderali MA, Xu SL, ... ... Gingras AC, et al. Systematic Discovery of Short Linear Motifs Decodes Calcineurin Phosphatase Signaling. Molecular Cell. PMID 32645368 DOI: 10.1016/J.Molcel.2020.06.029  0.387
2020 St-Germain J, Samavarchi Tehrani P, Wong C, Larsen B, Gingras AC, Raught B. Variability in streptavidin-sepharose matrix quality can significantly affect proximity-dependent biotinylation (BioID) data. Journal of Proteome Research. PMID 32628020 DOI: 10.1021/Acs.Jproteome.0C00117  0.644
2020 Fritz JL, Collins O, Saxena P, Buensuceso A, Ramos Valdes Y, Francis KE, Brown KR, Larsen B, Colwill K, Gingras AC, Rottapel R, Shepherd TG. A novel role for NUAK1 in promoting ovarian cancer metastasis through regulation of fibronectin production in spheroids. Cancers. 12. PMID 32429240 DOI: 10.3390/Cancers12051250  0.347
2020 Szewczyk MM, Ishikawa Y, Organ S, Sakai N, Li F, Halabelian L, Ackloo S, Couzens AL, Eram M, Dilworth D, Fukushi H, Harding R, Dela Seña CC, Sugo T, Hayashi K, ... ... Gingras AC, et al. Pharmacological inhibition of PRMT7 links arginine monomethylation to the cellular stress response. Nature Communications. 11: 2396. PMID 32409666 DOI: 10.1038/S41467-020-16271-Z  0.338
2020 Müller PM, Rademacher J, Bagshaw RD, Wortmann C, Barth C, van Unen J, Alp KM, Giudice G, Eccles RL, Heinrich LE, Pascual-Vargas P, Sanchez-Castro M, Brandenburg L, Mbamalu G, Tucholska M, ... ... Gingras AC, et al. Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions. Nature Cell Biology. PMID 32203420 DOI: 10.1038/S41556-020-0488-X  0.39
2020 Samavarchi-Tehrani P, Samson R, Gingras AC. Proximity dependent biotinylation: key enzymes and adaptation to proteomics approaches. Molecular & Cellular Proteomics : McP. PMID 32127388 DOI: 10.1074/Mcp.R120.001941  0.344
2020 Bagci H, Sriskandarajah N, Robert A, Boulais J, Elkholi IE, Tran V, Lin ZY, Thibault MP, Dubé N, Faubert D, Hipfner DR, Gingras AC, Côté JF. Author Correction: Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms. Nature Cell Biology. PMID 32042180 DOI: 10.1038/S41556-020-0479-Y  0.303
2020 Gonatopoulos-Pournatzis T, Niibori R, Salter EW, Weatheritt RJ, Tsang B, Farhangmehr S, Liang X, Braunschweig U, Roth J, Zhang S, Henderson T, Sharma E, Quesnel-Vallières M, Permanyer J, Maier S, ... ... Gingras AC, et al. Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions. Molecular Cell. PMID 31999954 DOI: 10.1016/J.Molcel.2020.01.006  0.475
2020 Merritt N, Garcia K, Rajendran D, Lin Z, Zhang X, Mitchell K, Fullenkamp C, Gingras A, Harvey K, Tanas M. Abstract B44: The TAZ-CAMTA1 and YAP-TFE3 fusion proteins transform cells by binding to subunits of the histone acetyltransferase Ada2a-containing complex (ATAC) Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-B44  0.449
2020 Ulengin-Talkish I, Bond R, St-Denis N, Gingras A, Shih A, Conibear E, Balla T, Varnai P, Cyert MS. Uncovering The Unique Functions And Regulation Of The Palmitoylated Calcineurin Isoform, CNβ1 The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07593  0.319
2020 Kawashima AG, Wong C, King CC, Gingras A, Newton A. CDK1‐dependent Phosphorylation of the Tumor Suppressor Phosphatase, PHLPP1, Regulates the Mitotic PHLPP1 Interactome The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05501  0.308
2019 Bagci H, Sriskandarajah N, Robert A, Boulais J, Elkholi IE, Tran V, Lin ZY, Thibault MP, Dubé N, Faubert D, Hipfner DR, Gingras AC, Côté JF. Mapping the proximity interaction network of the Rho-family GTPases reveals signalling pathways and regulatory mechanisms. Nature Cell Biology. PMID 31871319 DOI: 10.1038/S41556-019-0438-7  0.426
2019 Gingras AC. Connecting proteins: shareable tools for reproducible interaction mapping. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. PMID 31689129 DOI: 10.1139/Bcb-2019-0285  0.311
2019 Meant A, Gao B, Lavoie G, Nourreddine S, Jung F, Aubert L, Tcherkezian J, Gingras AC, Roux PP. Proteomic analysis reveals a role for RSK in p120-catenin phosphorylation and melanoma cell-cell adhesion. Molecular & Cellular Proteomics : McP. PMID 31678930 DOI: 10.1074/Mcp.Ra119.001811  0.414
2019 Youn JY, Dyakov BJA, Zhang J, Knight JDR, Vernon RM, Forman-Kay JD, Gingras AC. Properties of Stress Granule and P-Body Proteomes. Molecular Cell. 76: 286-294. PMID 31626750 DOI: 10.1016/J.Molcel.2019.09.014  0.37
2019 O'Connor CM, Leonard D, Wiredja D, Avelar RA, Wang Z, Schlatzer D, Bryson B, Tokala E, Taylor SE, Upadhyay A, Sangodkar J, Gingras AC, Westermarck J, Xu W, DiFeo A, et al. Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors. Oncogene. PMID 31541192 DOI: 10.1038/S41388-019-1012-2  0.336
2019 Lahaie S, Morales D, Bagci H, Hamoud N, Castonguay CE, Kazan JM, Desrochers G, Klar A, Gingras AC, Pause A, Côté JF, Kania A. The endosomal sorting adaptor HD-PTP is required for ephrin-B:EphB signalling in cellular collapse and spinal motor axon guidance. Scientific Reports. 9: 11945. PMID 31420572 DOI: 10.1038/S41598-019-48421-9  0.315
2019 O'Meara TR, O'Meara MJ, Polvi EJ, Pourhaghighi MR, Liston SD, Lin ZY, Veri AO, Emili A, Gingras AC, Cowen LE. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen. Plos Biology. 17: e3000358. PMID 31283755 DOI: 10.1371/Journal.Pbio.3000358  0.399
2019 Ceccarelli DF, Ivantsiv S, Mullin AA, Coyaud E, Manczyk N, Maisonneuve P, Kurinov I, Zhao L, Go C, Gingras AC, Raught B, Cordes S, Sicheri F. FAM105A/OTULINL Is a Pseudodebuiquitinase of the OTU-Class that Localizes to the ER Membrane. Structure (London, England : 1993). PMID 31056421 DOI: 10.1016/J.Str.2019.03.022  0.701
2019 Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskimäki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nature Communications. 10: 1791. PMID 30996251 DOI: 10.1038/S41467-019-09829-Z  0.328
2019 Torres-Méndez A, Bonnal S, Marquez Y, Roth J, Iglesias M, Permanyer J, Almudí I, O'Hanlon D, Guitart T, Soller M, Gingras AC, Gebauer F, Rentzsch F, Blencowe BJ, Valcárcel J, et al. A novel protein domain in an ancestral splicing factor drove the evolution of neural microexons. Nature Ecology & Evolution. PMID 30833759 DOI: 10.1038/S41559-019-0813-6  0.324
2019 Ashraf K, Nabeel-Shah S, Garg J, Saettone A, Derynck J, Gingras AC, Lambert JP, Pearlman RE, Fillingham J. Proteomic analysis of histones H2A/H2B and variant Hv1 in Tetrahymena thermophila reveals an ancient network of chaperones. Molecular Biology and Evolution. PMID 30796450 DOI: 10.1093/Molbev/Msz039  0.318
2018 Coyaud E, Ranadheera C, Cheng D, Gonçalves J, Dyakov BJA, Laurent EMN, St-Germain J, Pelletier L, Gingras AC, Brumell JH, Kim PK, Safronetz D, Raught B. Global Interactomics Uncovers Extensive Organellar Targeting by Zika Virus. Molecular & Cellular Proteomics : McP. 17: 2242-2255. PMID 33503773 DOI: 10.1074/mcp.TIR118.000800  0.672
2018 Gingras AC, Abe KT, Raught B. Getting to know the neighborhood: using proximity-dependent biotinylation to characterize protein complexes and map organelles. Current Opinion in Chemical Biology. 48: 44-54. PMID 30458335 DOI: 10.1016/J.Cbpa.2018.10.017  0.723
2018 Gonatopoulos-Pournatzis T, Wu M, Braunschweig U, Roth J, Han H, Best AJ, Raj B, Aregger M, O'Hanlon D, Ellis JD, Calarco JA, Moffat J, Gingras AC, Blencowe BJ. Genome-wide CRISPR-Cas9 Interrogation of Splicing Networks Reveals a Mechanism for Recognition of Autism-Misregulated Neuronal Microexons. Molecular Cell. 72: 510-524.e12. PMID 30388412 DOI: 10.1016/J.Molcel.2018.10.008  0.332
2018 Nishimura T, Fakim H, Brandmann T, Youn JY, Gingras AC, Jinek M, Fabian MR. Human MARF1 is an endoribonuclease that interacts with the DCP1:2 decapping complex and degrades target mRNAs. Nucleic Acids Research. PMID 30364987 DOI: 10.1093/Nar/Gky1011  0.363
2018 Emmer BT, Hesketh GG, Kotnik E, Tang VT, Lascuna PJ, Xiang J, Gingras AC, Chen XW, Ginsburg D. The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9. Elife. 7. PMID 30251625 DOI: 10.7554/Elife.38839  0.336
2018 Gill MK, Christova T, Zhang YY, Gregorieff A, Zhang L, Narimatsu M, Song S, Xiong S, Couzens AL, Tong J, Krieger JR, Moran MF, Zlotta AR, van der Kwast TH, Gingras AC, et al. A feed forward loop enforces YAP/TAZ signaling during tumorigenesis. Nature Communications. 9: 3510. PMID 30158528 DOI: 10.1038/S41467-018-05939-2  0.324
2018 Khoriaty R, Hesketh GG, Bernard A, Weyand AC, Mellacheruvu D, Zhu G, Hoenerhoff MJ, McGee B, Everett L, Adams EJ, Zhang B, Saunders TL, Nesvizhskii AI, Klionsky DJ, Shavit JA, ... Gingras AC, et al. Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 30065114 DOI: 10.1073/Pnas.1805784115  0.315
2018 Coyaud E, Ranadheera C, Cheng DT, Goncalves J, Dyakov B, Laurent E, St-Germain JR, Pelletier L, Gingras AC, Brumell JH, Kim PK, Safronetz D, Raught B. Global interactomics uncovers extensive organellar targeting by Zika virus. Molecular & Cellular Proteomics : McP. PMID 30037810 DOI: 10.1074/Mcp.Tir118.000800  0.694
2018 Noordermeer SM, Adam S, Setiaputra D, Barazas M, Pettitt SJ, Ling AK, Olivieri M, Álvarez-Quilón A, Moatti N, Zimmermann M, Annunziato S, Krastev DB, Song F, Brandsma I, Frankum J, ... ... Gingras AC, et al. The shieldin complex mediates 53BP1-dependent DNA repair. Nature. PMID 30022168 DOI: 10.1038/S41586-018-0340-7  0.326
2018 Samavarchi-Tehrani P, Abdouni H, Samson R, Gingras AC. A versatile lentiviral delivery toolkit for proximity-dependent biotinylation in diverse cell types. Molecular & Cellular Proteomics : McP. PMID 29991506 DOI: 10.1074/Mcp.Tir118.000902  0.388
2018 Xiong S, Lorenzen K, Couzens AL, Templeton CM, Rajendran D, Mao DYL, Juang YC, Chiovitti D, Kurinov I, Guettler S, Gingras AC, Sicheri F. Structural Basis for Auto-Inhibition of the NDR1 Kinase Domain by an Atypically Long Activation Segment. Structure (London, England : 1993). PMID 29983373 DOI: 10.1016/J.Str.2018.05.014  0.374
2018 Hunter MR, Hesketh GG, Benedyk TH, Gingras AC, Graham SC. Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B. Journal of Molecular Biology. PMID 29778605 DOI: 10.1016/J.Jmb.2018.05.019  0.416
2018 Saettone A, Garg J, Lambert JP, Nabeel-Shah S, Ponce M, Burtch A, Thuppu Mudalige C, Gingras AC, Pearlman RE, Fillingham J. The bromodomain-containing protein Ibd1 links multiple chromatin-related protein complexes to highly expressed genes in Tetrahymena thermophila. Epigenetics & Chromatin. 11: 10. PMID 29523178 DOI: 10.1186/S13072-018-0180-6  0.377
2018 Brandmann T, Fakim H, Padamsi Z, Youn JY, Gingras AC, Fabian MR, Jinek M. Molecular architecture of LSM14 interactions involved in the assembly of mRNA silencing complexes. The Embo Journal. PMID 29510985 DOI: 10.15252/Embj.201797869  0.395
2018 Jafarnejad SM, Chapat C, Matta-Camacho E, Gelbart IA, Hesketh GG, Arguello M, Garzia A, Kim SH, Attig J, Shapiro M, Morita M, Khoutorsky A, Alain T, Gkogkas C, Stern-Ginossar N, ... ... Gingras AC, et al. Translational control of ERK signaling through miRNA/4EHP-directed silencing. Elife. 7. PMID 29412140 DOI: 10.7554/Elife.35034  0.776
2018 Youn JY, Dunham WH, Hong SJ, Knight JDR, Bashkurov M, Chen GI, Bagci H, Rathod B, MacLeod G, Eng SWM, Angers S, Morris Q, Fabian M, Côté JF, Gingras AC. High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies. Molecular Cell. 69: 517-532.e11. PMID 29395067 DOI: 10.1016/J.Molcel.2017.12.020  0.44
2018 Merritt N, Rajendran D, Lin Z, Zhang X, Mitchell K, Fullenkamp C, Gingras A, Harvey K, Tanas M. Abstract 3359: Elucidating the oncogenic mechanism of the TAZ-CAMTA1 and YAP-TFE3 fusion proteins Cancer Research. 78: 3359-3359. DOI: 10.1158/1538-7445.Am2018-3359  0.43
2017 Sandí MJ, Marshall CB, Balan M, Coyaud É, Zhou M, Monson DM, Ishiyama N, Chandrakumar AA, La Rose J, Couzens AL, Gingras AC, Raught B, Xu W, Ikura M, Morrison DK, et al. MARK3-mediated phosphorylation of ARHGEF2 couples microtubules to the actin cytoskeleton to establish cell polarity. Science Signaling. 10. PMID 29089450 DOI: 10.1126/Scisignal.Aan3286  0.715
2017 Smith MJ, Ottoni E, Ishiyama N, Goudreault M, Haman A, Meyer C, Tucholska M, Gasmi-Seabrook G, Menezes S, Laister RC, Minden MD, Marschalek R, Gingras AC, Hoang T, Ikura M. Evolution of AF6-RAS association and its implications in mixed-lineage leukemia. Nature Communications. 8: 1099. PMID 29062045 DOI: 10.1038/S41467-017-01326-5  0.331
2017 Collins BC, Hunter CL, Liu Y, Schilling B, Rosenberger G, Bader SL, Chan DW, Gibson BW, Gingras AC, Held JM, Hirayama-Kurogi M, Hou G, Krisp C, Larsen B, Lin L, et al. Multi-laboratory assessment of reproducibility, qualitative and quantitative performance of SWATH-mass spectrometry. Nature Communications. 8: 291. PMID 28827567 DOI: 10.1038/S41467-017-00249-5  0.399
2017 Gu B, Lambert JP, Cockburn K, Gingras AC, Rossant J. AIRE is a critical spindle-associated protein in embryonic stem cells. Elife. 6. PMID 28742026 DOI: 10.7554/Elife.28131  0.339
2017 Gueroussov S, Weatheritt RJ, O'Hanlon D, Lin ZY, Narula A, Gingras AC, Blencowe BJ. Regulatory Expansion in Mammals of Multivalent hnRNP Assemblies that Globally Control Alternative Splicing. Cell. 170: 324-339.e23. PMID 28709000 DOI: 10.1016/J.Cell.2017.06.037  0.411
2017 Knight JDR, Choi H, Gupta GD, Pelletier L, Raught B, Nesvizhskii AI, Gingras AC. ProHits-viz: a suite of web tools for visualizing interaction proteomics data. Nature Methods. 14: 645-646. PMID 28661499 DOI: 10.1038/Nmeth.4330  0.615
2017 Mojarad BA, Gupta GD, Hasegan M, Goudiam O, Basto R, Gingras AC, Pelletier L. CEP19 cooperates with FOP and CEP350 to drive early steps in the ciliogenesis programme. Open Biology. 7. PMID 28659385 DOI: 10.1098/Rsob.170114  0.356
2017 Courcelles M, Coulombe-Huntington J, Cossette É, Gingras AC, Thibault P, Tyers M. CLMSVault: a software suite for protein cross-linking mass spectrometry data analysis and visualization. Journal of Proteome Research. PMID 28537071 DOI: 10.1021/Acs.Jproteome.7B00205  0.352
2017 Chapat C, Jafarnejad SM, Matta-Camacho E, Hesketh GG, Gelbart IA, Attig J, Gkogkas CG, Alain T, Stern-Ginossar N, Fabian MR, Gingras AC, Duchaine TF, Sonenberg N. Cap-binding protein 4EHP effects translation silencing by microRNAs. Proceedings of the National Academy of Sciences of the United States of America. PMID 28487484 DOI: 10.1073/Pnas.1701488114  0.727
2017 Couzens AL, Xiong S, Knight JD, Mao DY, Guettler S, Picaud S, Kurinov I, Filippakopoulos P, Sicheri F, Gingras AC. MOB1 mediated phospho-recognition in the core mammalian Hippo pathway. Molecular & Cellular Proteomics : McP. PMID 28373298 DOI: 10.1074/Mcp.M116.065490  0.445
2017 Xiong S, Couzens AL, Kean MJ, Mao DY, Guettler S, Kurinov I, Gingras AC, Sicheri F. Regulation of protein interactions by MOB1 phosphorylation. Molecular & Cellular Proteomics : McP. PMID 28373297 DOI: 10.1074/Mcp.M117.068130  0.474
2017 Pal S, Lant B, Yu B, Tian R, Tong J, Krieger JR, Moran MF, Gingras AC, Derry WB. CCM-3 Promotes C. elegans Germline Development by Regulating Vesicle Trafficking Cytokinesis and Polarity. Current Biology : Cb. PMID 28285997 DOI: 10.1016/J.Cub.2017.02.028  0.351
2017 Hesketh GG, Youn JY, Samavarchi-Tehrani P, Raught B, Gingras AC. Parallel Exploration of Interaction Space by BioID and Affinity Purification Coupled to Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1550: 115-136. PMID 28188527 DOI: 10.1007/978-1-4939-6747-6_10  0.711
2016 Yao Z, Darowski K, St-Denis N, Wong V, Offensperger F, Villedieu A, Amin S, Malty R, Aoki H, Guo H, Xu Y, Iorio C, Kotlyar M, Emili A, Jurisica I, ... ... Gingras AC, et al. A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. Molecular Cell. PMID 28065597 DOI: 10.1016/J.Molcel.2016.12.004  0.432
2016 Antonicka H, Choquet K, Lin ZY, Gingras AC, Kleinman CL, Shoubridge EA. A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability. Embo Reports. PMID 27974379 DOI: 10.15252/Embr.201643391  0.343
2016 Uhrig G, Labandera AM, Tang LY, Sieben NA, Goudreault M, Yeung EC, Gingras AC, Samuel M, Moorhead GB. Activation of mitochondrial protein phosphatase SLP2 by MIA40 regulates seed germination. Plant Physiology. PMID 27923987 DOI: 10.1104/Pp.16.01641  0.439
2016 Wan LC, Maisonneuve P, Szilard RK, Lambert JP, Ng TF, Manczyk N, Huang H, Laister R, Caudy AA, Gingras AC, Durocher D, Sicheri F. Proteomic analysis of the human KEOPS complex identifies C14ORF142 as a core subunit homologous to yeast Gon7. Nucleic Acids Research. PMID 27903914 DOI: 10.1093/Nar/Gkw1181  0.368
2016 St-Denis N, Gupta GD, Lin ZY, Gonzalez-Badillo B, Veri AO, Knight JD, Rajendran D, Couzens AL, Currie KW, Tkach JM, Cheung SW, Pelletier L, Gingras AC. Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators. Cell Reports. 17: 2488-2501. PMID 27880917 DOI: 10.1016/J.Celrep.2016.10.078  0.405
2016 Kazazian K, Go CD, Wu H, Brashavitskaya O, Xu RS, Dennis JW, Gingras AC, Swallow C. Plk4 promotes cancer invasion and metastasis through Arp2/3 complex regulation of the actin cytoskeleton. Cancer Research. PMID 27872092 DOI: 10.1158/0008-5472.Can-16-2060  0.314
2016 Picaud S, Leonards K, Lambert JP, Dovey O, Wells C, Fedorov O, Monteiro O, Fujisawa T, Wang CY, Lingard H, Tallant C, Nikbin N, Guetzoyan L, Ingham R, Ley SV, ... ... Gingras AC, et al. Promiscuous targeting of bromodomains by bromosporine identifies BET proteins as master regulators of primary transcription response in leukemia. Science Advances. 2: e1600760. PMID 27757418 DOI: 10.1126/Sciadv.1600760  0.378
2016 Costanzo M, VanderSluis B, Koch EN, Baryshnikova A, Pons C, Tan G, Wang W, Usaj M, Hanchard J, Lee SD, Pelechano V, Styles EB, Billmann M, van Leeuwen J, van Dyk N, ... ... Gingras AC, et al. A global genetic interaction network maps a wiring diagram of cellular function. Science (New York, N.Y.). 353. PMID 27708008 DOI: 10.1126/Science.Aaf1420  0.653
2016 Uusküla-Reimand L, Hou H, Samavarchi-Tehrani P, Rudan MV, Liang M, Medina-Rivera A, Mohammed H, Schmidt D, Schwalie P, Young EJ, Reimand J, Hadjur S, Gingras AC, Wilson MD. Topoisomerase II beta interacts with cohesin and CTCF at topological domain borders. Genome Biology. 17: 182. PMID 27582050 DOI: 10.1186/S13059-016-1043-8  0.307
2016 Shekhar-Guturja T, Gunaherath GM, Wijeratne EM, Lambert JP, Averette AF, Lee SC, Kim T, Bahn YS, Tripodi F, Ammar R, Döhl K, Niewola-Staszkowska K, Schmitt L, Loewith RJ, Roth FP, ... ... Gingras AC, et al. Dual action antifungal small molecule modulates multidrug efflux and TOR signaling. Nature Chemical Biology. PMID 27571477 DOI: 10.1038/Nchembio.2165  0.314
2016 Campbell CI, Samavarchi-Tehrani P, Barrios-Rodiles M, Datti A, Gingras AC, Wrana JL. The RNF146/Tankyrase pathway maintains the junctional Crumbs complex through regulation of Angiomotin. Journal of Cell Science. PMID 27521426 DOI: 10.1242/Jcs.188417  0.389
2016 Gingras AC, Wong CJ. Proteomics approaches to decipher new signaling pathways. Current Opinion in Structural Biology. 41: 128-134. PMID 27449970 DOI: 10.1016/J.Sbi.2016.07.008  0.337
2016 Jacquet K, Fradet-Turcotte A, Avvakumov N, Lambert JP, Roques C, Pandita RK, Paquet E, Herst P, Gingras AC, Pandita TK, Legube G, Doyon Y, Durocher D, Côté J. The TIP60 Complex Regulates Bivalent Chromatin Recognition by 53BP1 through Direct H4K20me Binding and H2AK15 Acetylation. Molecular Cell. 62: 409-21. PMID 27153538 DOI: 10.1016/J.Molcel.2016.03.031  0.348
2016 Liu G, Knight JD, Zhang JP, Tsou CC, Wang J, Lambert JP, Larsen B, Tyers M, Raught B, Bandeira N, Nesvizhskii AI, Choi H, Gingras AC. Data Independent Acquisition analysis in ProHits 4.0. Journal of Proteomics. PMID 27132685 DOI: 10.1016/J.Jprot.2016.04.042  0.654
2016 Teo G, Koh H, Fermin D, Lambert JP, Knight JD, Gingras AC, Choi H. SAINTq: scoring protein-protein interactions in affinity purification - mass spectrometry experiments with fragment or peptide intensity data. Proteomics. PMID 27119218 DOI: 10.1002/Pmic.201500499  0.365
2016 Chattopadhyay D, Swingle MR, Salter EA, Wood E, D'Arcy B, Zivanov C, Abney K, Musiyenko A, Rusin SF, Kettenbach A, Yet L, Schroeder CE, Golden JE, Dunham WH, Gingras AC, et al. Crystal Structures and Mutagenesis of PPP-family ser/thr Protein Phosphatases Elucidate the Selectivity of Cantharidin and Novel Norcantharidin-based Inhibitors of PP5C. Biochemical Pharmacology. PMID 27002182 DOI: 10.1016/J.Bcp.2016.03.011  0.31
2016 de Kreuk BJ, Gingras AR, Knight JD, Liu JJ, Gingras AC, Ginsberg MH. Heart of glass anchors Rasip1 at endothelial cell-cell junctions to support vascular integrity. Elife. 5. PMID 26780829 DOI: 10.7554/Elife.11394  0.322
2015 Gupta GD, Coyaud É, Gonçalves J, Mojarad BA, Liu Y, Wu Q, Gheiratmand L, Comartin D, Tkach JM, Cheung SW, Bashkurov M, Hasegan M, Knight JD, Lin ZY, Schueler M, ... ... Gingras AC, et al. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. Cell. 163: 1484-99. PMID 26638075 DOI: 10.1016/J.Cell.2015.10.065  0.721
2015 Gueroussov S, Gonatopoulos-Pournatzis T, Irimia M, Raj B, Lin ZY, Gingras AC, Blencowe BJ. RNA SPLICING. An alternative splicing event amplifies evolutionary differences between vertebrates. Science (New York, N.Y.). 349: 868-73. PMID 26293963 DOI: 10.1126/Science.Aaa8381  0.336
2015 Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, Dębski J, Uusi-Rauva K, Dadlez M, Gingras AC, Tyynelä J, Simonati A, Jalanko A, Baumann MH, Lalowski M. Quantitative analysis of PPT1 interactome in human neuroblastoma cells. Data in Brief. 4: 207-16. PMID 26217791 DOI: 10.1016/J.Dib.2015.05.016  0.37
2015 Marcon E, Jain H, Bhattacharya A, Guo H, Phanse S, Pu S, Byram G, Collins BC, Dowdell E, Fenner M, Guo X, Hutchinson A, Kennedy JJ, Krastins B, Larsen B, ... ... Gingras AC, et al. Assessment of a method to characterize antibody selectivity and specificity for use in immunoprecipitation. Nature Methods. PMID 26121405 DOI: 10.1038/Nmeth.3472  0.379
2015 Mui MZ, Zhou Y, Blanchette P, Chughtai N, Knight JF, Gruosso T, Papadakis AI, Huang S, Park M, Gingras AC, Branton PE. The human adenovirus type 5 E4orf4 protein targets two phosphatase regulators of the Hippo signaling pathway. Journal of Virology. PMID 26085163 DOI: 10.1128/Jvi.03710-14  0.42
2015 Nishimura T, Padamsi Z, Fakim H, Milette S, Dunham WH, Gingras AC, Fabian MR. The eIF4E-Binding Protein 4E-T Is a Component of the mRNA Decay Machinery that Bridges the 5' and 3' Termini of Target mRNAs. Cell Reports. 11: 1425-36. PMID 26027925 DOI: 10.1016/J.Celrep.2015.04.065  0.378
2015 Coyaud E, Mis M, Laurent EM, Dunham WH, Couzens AL, Robitaille M, Gingras AC, Angers S, Raught B. BioID-based Identification of Skp Cullin F-box (SCF)β-TrCP1/2 E3 Ligase Substrates. Molecular & Cellular Proteomics : McP. 14: 1781-95. PMID 25900982 DOI: 10.1074/Mcp.M114.045658  0.684
2015 Scifo E, Szwajda A, Soliymani R, Pezzini F, Bianchi M, Dapkunas A, D?bski J, Uusi-Rauva K, Dadlez M, Gingras AC, Tyynelä J, Simonati A, Jalanko A, Baumann MH, Lalowski M. Proteomic analysis of the palmitoyl protein thioesterase 1 interactome in SH-SY5Y human neuroblastoma cells. Journal of Proteomics. 123: 42-53. PMID 25865307 DOI: 10.1016/J.Jprot.2015.03.038  0.357
2015 Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: E1594-603. PMID 25829543 DOI: 10.1073/Pnas.1503286112  0.316
2015 Lant B, Yu B, Goudreault M, Holmyard D, Knight JD, Xu P, Zhao L, Chin K, Wallace E, Zhen M, Gingras AC, Derry WB. CCM-3/STRIPAK promotes seamless tube extension through endocytic recycling. Nature Communications. 6: 6449. PMID 25743393 DOI: 10.1038/Ncomms7449  0.308
2015 St-Denis N, Gupta GD, Lin ZY, Gonzalez-Badillo B, Pelletier L, Gingras AC. Myotubularin-related proteins 3 and 4 interact with polo-like kinase 1 and centrosomal protein of 55 kDa to ensure proper abscission. Molecular & Cellular Proteomics : McP. 14: 946-60. PMID 25659891 DOI: 10.1074/Mcp.M114.046086  0.469
2015 Knight JD, Liu G, Zhang JP, Pasculescu A, Choi H, Gingras AC. A web-tool for visualizing quantitative protein-protein interaction data. Proteomics. 15: 1432-6. PMID 25422071 DOI: 10.1002/Pmic.201400429  0.363
2015 Lambert JP, Tucholska M, Go C, Knight JD, Gingras AC. Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes. Journal of Proteomics. 118: 81-94. PMID 25281560 DOI: 10.1016/J.Jprot.2014.09.011  0.434
2015 Lambert J, Zhou Y, Couzens A, Tsou C, Picaud S, Ivosev G, Tate S, Nesvizhskii A, Filippakopoulos P, Gingras A. Abstract IA19: Regulation of signaling interactomes in cancer Cancer Research. 75. DOI: 10.1158/1538-7445.Compsysbio-Ia19  0.41
2014 Liu YC, Couzens AL, Deshwar AR, B McBroom-Cerajewski LD, Zhang X, Puviindran V, Scott IC, Gingras AC, Hui CC, Angers S. The PPFIA1-PP2A protein complex promotes trafficking of Kif7 to the ciliary tip and Hedgehog signaling. Science Signaling. 7: ra117. PMID 25492966 DOI: 10.1126/Scisignal.2005608  0.435
2014 Gray EJ, Petsalaki E, James DA, Bagshaw RD, Stacey MM, Rocks O, Gingras AC, Pawson T. Src homology 2 domain containing protein 5 (SH2D5) binds the breakpoint cluster region protein, BCR, and regulates levels of Rac1-GTP. The Journal of Biological Chemistry. 289: 35397-408. PMID 25331951 DOI: 10.1074/Jbc.M114.615112  0.371
2014 Raj B, Irimia M, Braunschweig U, Sterne-Weiler T, O'Hanlon D, Lin ZY, Chen GI, Easton LE, Ule J, Gingras AC, Eyras E, Blencowe BJ. A global regulatory mechanism for activating an exon network required for neurogenesis. Molecular Cell. 56: 90-103. PMID 25219497 DOI: 10.1016/J.Molcel.2014.08.011  0.36
2014 Meiri D, Marshall CB, Mokady D, LaRose J, Mullin M, Gingras AC, Ikura M, Rottapel R. Mechanistic insight into GPCR-mediated activation of the microtubule-associated RhoA exchange factor GEF-H1. Nature Communications. 5: 4857. PMID 25209408 DOI: 10.1038/Ncomms5857  0.323
2014 Barsyte-Lovejoy D, Li F, Oudhoff MJ, Tatlock JH, Dong A, Zeng H, Wu H, Freeman SA, Schapira M, Senisterra GA, Kuznetsova E, Marcellus R, Allali-Hassani A, Kennedy S, Lambert JP, ... ... Gingras AC, et al. (R)-PFI-2 is a potent and selective inhibitor of SETD7 methyltransferase activity in cells. Proceedings of the National Academy of Sciences of the United States of America. 111: 12853-8. PMID 25136132 DOI: 10.1073/Pnas.1407358111  0.329
2014 Philpott M, Rogers CM, Yapp C, Wells C, Lambert JP, Strain-Damerell C, Burgess-Brown NA, Gingras AC, Knapp S, Müller S. Assessing cellular efficacy of bromodomain inhibitors using fluorescence recovery after photobleaching. Epigenetics & Chromatin. 7: 14. PMID 25097667 DOI: 10.1186/1756-8935-7-14  0.343
2014 Taipale M, Tucker G, Peng J, Krykbaeva I, Lin ZY, Larsen B, Choi H, Berger B, Gingras AC, Lindquist S. A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways. Cell. 158: 434-48. PMID 25036637 DOI: 10.1016/J.Cell.2014.05.039  0.313
2014 Jovi? M, Kean MJ, Dubankova A, Boura E, Gingras AC, Brill JA, Balla T. Endosomal sorting of VAMP3 is regulated by PI4K2A. Journal of Cell Science. 127: 3745-56. PMID 25002402 DOI: 10.1242/Jcs.148809  0.384
2014 O'Neill DJ, Williamson SC, Alkharaif D, Monteiro IC, Goudreault M, Gaughan L, Robson CN, Gingras AC, Binda O. SETD6 controls the expression of estrogen-responsive genes and proliferation of breast carcinoma cells. Epigenetics : Official Journal of the Dna Methylation Society. 9: 942-50. PMID 24751716 DOI: 10.4161/Epi.28864  0.33
2014 Rojas M, Gingras AC, Dever TE. Protein phosphatase PP1/GLC7 interaction domain in yeast eIF2γ bypasses targeting subunit requirement for eIF2α dephosphorylation Proceedings of the National Academy of Sciences of the United States of America. 111: E1344-E1353. PMID 24706853 DOI: 10.1073/Pnas.1400129111  0.432
2014 Sakamaki J, Fu A, Reeks C, Baird S, Depatie C, Al Azzabi M, Bardeesy N, Gingras AC, Yee SP, Screaton RA. Role of the SIK2-p35-PJA2 complex in pancreatic β-cell functional compensation. Nature Cell Biology. 16: 234-44. PMID 24561619 DOI: 10.1038/Ncb2919  0.309
2014 Lambert JP, Tucholska M, Pawson T, Gingras AC. Incorporating DNA shearing in standard affinity purification allows simultaneous identification of both soluble and chromatin-bound interaction partners. Journal of Proteomics. 100: 55-9. PMID 24412199 DOI: 10.1016/J.Jprot.2013.12.022  0.348
2013 Couzens AL, Knight JD, Kean MJ, Teo G, Weiss A, Dunham WH, Lin ZY, Bagshaw RD, Sicheri F, Pawson T, Wrana JL, Choi H, Gingras AC. Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. Science Signaling. 6: rs15. PMID 24255178 DOI: 10.1126/Scisignal.2004712  0.474
2013 Lambert JP, Ivosev G, Couzens AL, Larsen B, Taipale M, Lin ZY, Zhong Q, Lindquist S, Vidal M, Aebersold R, Pawson T, Bonner R, Tate S, Gingras AC. Mapping differential interactomes by affinity purification coupled with data-independent mass spectrometry acquisition. Nature Methods. 10: 1239-45. PMID 24162924 DOI: 10.1038/Nmeth.2702  0.551
2013 Garg J, Lambert JP, Karsou A, Marquez S, Nabeel-Shah S, Bertucci V, Retnasothie DV, Radovani E, Pawson T, Gingras AC, Pearlman RE, Fillingham JS. Conserved Asf1-importin β physical interaction in growth and sexual development in the ciliate Tetrahymena thermophila. Journal of Proteomics. 94: 311-26. PMID 24120531 DOI: 10.1016/J.Jprot.2013.09.018  0.358
2013 Mellacheruvu D, Wright Z, Couzens AL, Lambert JP, St-Denis NA, Li T, Miteva YV, Hauri S, Sardiu ME, Low TY, Halim VA, Bagshaw RD, Hubner NC, Al-Hakim A, Bouchard A, ... ... Gingras AC, et al. The CRAPome: a contaminant repository for affinity purification-mass spectrometry data. Nature Methods. 10: 730-6. PMID 23921808 DOI: 10.1038/Nmeth.2557  0.731
2013 Oudhoff MJ, Freeman SA, Couzens AL, Antignano F, Kuznetsova E, Min PH, Northrop JP, Lehnertz B, Barsyte-Lovejoy D, Vedadi M, Arrowsmith CH, Nishina H, Gold MR, Rossi FM, Gingras AC, et al. Control of the hippo pathway by Set7-dependent methylation of Yap. Developmental Cell. 26: 188-94. PMID 23850191 DOI: 10.1016/J.Devcel.2013.05.025  0.362
2013 Zheng Y, Zhang C, Croucher DR, Soliman MA, St-Denis N, Pasculescu A, Taylor L, Tate SA, Hardy WR, Colwill K, Dai AY, Bagshaw R, Dennis JW, Gingras AC, Daly RJ, et al. Temporal regulation of EGF signalling networks by the scaffold protein Shc1. Nature. 499: 166-71. PMID 23846654 DOI: 10.1038/Nature12308  0.457
2013 Rivkin E, Almeida SM, Ceccarelli DF, Juang YC, MacLean TA, Srikumar T, Huang H, Dunham WH, Fukumura R, Xie G, Gondo Y, Raught B, Gingras AC, Sicheri F, Cordes SP. The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. Nature. 498: 318-24. PMID 23708998 DOI: 10.1038/Nature12296  0.692
2013 Newman RH, Hu J, Rho HS, Xie Z, Woodard C, Neiswinger J, Cooper C, Shirley M, Clark HM, Hu S, Hwang W, Jeong JS, Wu G, Lin J, Gao X, ... ... Gingras AC, et al. Construction of human activity-based phosphorylation networks. Molecular Systems Biology. 9: 655. PMID 23549483 DOI: 10.1038/Msb.2013.12  0.401
2013 Scifo E, Szwajda A, D?bski J, Uusi-Rauva K, Kesti T, Dadlez M, Gingras AC, Tyynelä J, Baumann MH, Jalanko A, Lalowski M. Drafting the CLN3 protein interactome in SH-SY5Y human neuroblastoma cells: a label-free quantitative proteomics approach. Journal of Proteome Research. 12: 2101-15. PMID 23464991 DOI: 10.1021/Pr301125K  0.384
2013 Tate S, Larsen B, Bonner R, Gingras AC. Label-free quantitative proteomics trends for protein-protein interactions. Journal of Proteomics. 81: 91-101. PMID 23153790 DOI: 10.1016/J.Jprot.2012.10.027  0.397
2013 Knight JD, Pawson T, Gingras AC. Profiling the kinome: current capabilities and future challenges. Journal of Proteomics. 81: 43-55. PMID 23099349 DOI: 10.1016/J.Jprot.2012.10.015  0.398
2013 Scifo E, Szwajda A, Dębski J, Uusi-Rauva K, Kesti T, Dadlez M, Gingras A, Tyynelä J, Baumann MH, Jalanko A, Lalowski M. Correction to Drafting the CLN3 Protein Interactome in SH-SY5Y Human Neuroblastoma Cells: A Label-free Quantitative Proteomics Approach Journal of Proteome Research. 12: 3822-3822. DOI: 10.1021/Pr4005212  0.342
2012 Oberg EA, Nifoussi SK, Gingras AC, Strack S. Selective proteasomal degradation of the B'β subunit of protein phosphatase 2A by the E3 ubiquitin ligase adaptor Kelch-like 15. The Journal of Biological Chemistry. 287: 43378-89. PMID 23135275 DOI: 10.1074/Jbc.M112.420281  0.385
2012 Liu G, Zhang J, Choi H, Lambert JP, Srikumar T, Larsen B, Nesvizhskii AI, Raught B, Tyers M, Gingras AC. Using ProHits to store, annotate, and analyze affinity purification-mass spectrometry (AP-MS) data. Current Protocols in Bioinformatics / Editoral Board, Andreas D. Baxevanis ... [Et Al.]. Unit8.16. PMID 22948730 DOI: 10.1002/0471250953.Bi0816S39  0.652
2012 Gomez-Ferreria MA, Bashkurov M, Mullin M, Gingras AC, Pelletier L. CEP192 interacts physically and functionally with the K63-deubiquitinase CYLD to promote mitotic spindle assembly Cell Cycle. 11: 3555-3558. PMID 22895009 DOI: 10.4161/Cc.21574  0.406
2012 Belozerov VE, Lin ZY, Gingras AC, McDermott JC, Michael Siu KW. High-resolution protein interaction map of the Drosophila melanogaster p38 mitogen-activated protein kinases reveals limited functional redundancy. Molecular and Cellular Biology. 32: 3695-706. PMID 22801366 DOI: 10.1128/Mcb.00232-12  0.447
2012 van Zuylen WJ, Doyon P, Clément JF, Khan KA, D'Ambrosio LM, Dô F, St-Amant-Verret M, Wissanji T, Emery G, Gingras AC, Meloche S, Servant MJ. Proteomic profiling of the TRAF3 interactome network reveals a new role for the ER-to-Golgi transport compartments in innate immunity. Plos Pathogens. 8: e1002747. PMID 22792062 DOI: 10.1371/Journal.Ppat.1002747  0.342
2012 Morita M, Ler LW, Fabian MR, Siddiqui N, Mullin M, Henderson VC, Alain T, Fonseca BD, Karashchuk G, Bennett CF, Kabuta T, Higashi S, Larsson O, Topisirovic I, Smith RJ, ... Gingras AC, et al. A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development. Molecular and Cellular Biology. 32: 3585-93. PMID 22751931 DOI: 10.1128/Mcb.00455-12  0.529
2012 Braun P, Gingras AC. History of protein-protein interactions: from egg-white to complex networks. Proteomics. 12: 1478-98. PMID 22711592 DOI: 10.1002/Pmic.201100563  0.388
2012 Gingras AC, Nesvizhskii A. Protein complexes and interaction networks. Proteomics. 12: 1475-7. PMID 22711591 DOI: 10.1002/Pmic.201270054  0.338
2012 Gingras AC, Raught B. Beyond hairballs: The use of quantitative mass spectrometry data to understand protein-protein interactions. Febs Letters. 586: 2723-31. PMID 22710165 DOI: 10.1016/J.Febslet.2012.03.065  0.705
2012 Kean MJ, Couzens AL, Gingras AC. Mass spectrometry approaches to study mammalian kinase and phosphatase associated proteins. Methods (San Diego, Calif.). 57: 400-8. PMID 22710030 DOI: 10.1016/J.Ymeth.2012.06.002  0.471
2012 Dunham WH, Mullin M, Gingras AC. Affinity-purification coupled to mass spectrometry: basic principles and strategies. Proteomics. 12: 1576-90. PMID 22611051 DOI: 10.1002/Pmic.201100523  0.421
2012 Lambert JP, Pawson T, Gingras AC. Mapping physical interactions within chromatin by proteomic approaches. Proteomics. 12: 1609-22. PMID 22611019 DOI: 10.1002/Pmic.201100547  0.397
2012 Gomez-Ferreria MA, Bashkurov M, Helbig AO, Larsen B, Pawson T, Gingras AC, Pelletier L. Novel NEDD1 phosphorylation sites regulate γ-tubulin binding and mitotic spindle assembly. Journal of Cell Science. 125: 3745-51. PMID 22595525 DOI: 10.1242/Jcs.105130  0.388
2012 Filippakopoulos P, Picaud S, Mangos M, Keates T, Lambert JP, Barsyte-Lovejoy D, Felletar I, Volkmer R, Müller S, Pawson T, Gingras AC, Arrowsmith CH, Knapp S. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell. 149: 214-31. PMID 22464331 DOI: 10.1016/J.Cell.2012.02.013  0.307
2012 Knight JD, Tian R, Lee RE, Wang F, Beauvais A, Zou H, Megeney LA, Gingras AC, Pawson T, Figeys D, Kothary R. A novel whole-cell lysate kinase assay identifies substrates of the p38 MAPK in differentiating myoblasts. Skeletal Muscle. 2: 5. PMID 22394512 DOI: 10.1186/2044-5040-2-5  0.602
2012 St-Denis N, Gingras AC. Mass spectrometric tools for systematic analysis of protein phosphorylation. Progress in Molecular Biology and Translational Science. 106: 3-32. PMID 22340712 DOI: 10.1016/B978-0-12-396456-4.00014-6  0.461
2012 Jović M, Kean MJ, Szentpetery Z, Polevoy G, Gingras AC, Brill JA, Balla T. Two phosphatidylinositol 4-kinases control lysosomal delivery of the Gaucher disease enzyme, β-glucocerebrosidase. Molecular Biology of the Cell. 23: 1533-45. PMID 22337770 DOI: 10.1091/Mbc.E11-06-0553  0.362
2012 Al-Hakim AK, Bashkurov M, Gingras AC, Durocher D, Pelletier L. Interaction proteomics identify NEURL4 and the HECT E3 ligase HERC2 as novel modulators of centrosome architecture. Molecular & Cellular Proteomics : McP. 11: M111.014233. PMID 22261722 DOI: 10.1074/Mcp.M111.014233  0.419
2011 Dunham WH, Larsen B, Tate S, Badillo BG, Goudreault M, Tehami Y, Kislinger T, Gingras AC. A cost-benefit analysis of multidimensional fractionation of affinity purification-mass spectrometry samples. Proteomics. 11: 2603-12. PMID 21630450 DOI: 10.1002/Pmic.201000571  0.348
2011 Ceccarelli DF, Laister RC, Mulligan VK, Kean MJ, Goudreault M, Scott IC, Derry WB, Chakrabartty A, Gingras AC, Sicheri F. CCM3/PDCD10 heterodimerizes with germinal center kinase III (GCKIII) proteins using a mechanism analogous to CCM3 homodimerization. The Journal of Biological Chemistry. 286: 25056-64. PMID 21561863 DOI: 10.1074/Jbc.M110.213777  0.431
2011 Kean MJ, Ceccarelli DF, Goudreault M, Sanches M, Tate S, Larsen B, Gibson LC, Derry WB, Scott IC, Pelletier L, Baillie GS, Sicheri F, Gingras AC. Structure-function analysis of core STRIPAK Proteins: a signaling complex implicated in Golgi polarization. The Journal of Biological Chemistry. 286: 25065-75. PMID 21561862 DOI: 10.1074/Jbc.M110.214486  0.323
2011 Skarra DV, Goudreault M, Choi H, Mullin M, Nesvizhskii AI, Gingras AC, Honkanen RE. Label-free quantitative proteomics and SAINT analysis enable interactome mapping for the human Ser/Thr protein phosphatase 5 Proteomics. 11: 1508-1516. PMID 21360678 DOI: 10.1002/Pmic.201000770  0.307
2011 Templeton GW, Nimick M, Morrice N, Campbell D, Goudreault M, Gingras AC, Takemiya A, Shimazaki K, Moorhead GB. Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit. The Biochemical Journal. 435: 73-83. PMID 21222654 DOI: 10.1042/Bj20101035  0.408
2010 Liu G, Zhang J, Larsen B, Stark C, Breitkreutz A, Lin ZY, Breitkreutz BJ, Ding Y, Colwill K, Pasculescu A, Pawson T, Wrana JL, Nesvizhskii AI, Raught B, Tyers M, ... Gingras AC, et al. ProHits: integrated software for mass spectrometry-based interaction proteomics. Nature Biotechnology. 28: 1015-7. PMID 20944583 DOI: 10.1038/Nbt1010-1015  0.659
2010 Sydorskyy Y, Srikumar T, Jeram SM, Wheaton S, Vizeacoumar FJ, Makhnevych T, Chong YT, Gingras AC, Raught B. A novel mechanism for SUMO system control: regulated Ulp1 nucleolar sequestration. Molecular and Cellular Biology. 30: 4452-62. PMID 20647537 DOI: 10.1128/Mcb.00335-10  0.683
2010 Breitkreutz A, Choi H, Sharom JR, Boucher L, Neduva V, Larsen B, Lin ZY, Breitkreutz BJ, Stark C, Liu G, Ahn J, Dewar-Darch D, Reguly T, Tang X, Almeida R, ... ... Gingras AC, et al. A global protein kinase and phosphatase interaction network in yeast. Science (New York, N.Y.). 328: 1043-6. PMID 20489023 DOI: 10.1126/Science.1176495  0.325
2010 Bidinosti M, Ran I, Sanchez-Carbente MR, Martineau Y, Gingras AC, Gkogkas C, Raught B, Bramham CR, Sossin WS, Costa-Mattioli M, DesGroseillers L, Lacaille JC, Sonenberg N. Postnatal deamidation of 4E-BP2 in brain enhances its association with raptor and alters kinetics of excitatory synaptic transmission. Molecular Cell. 37: 797-808. PMID 20347422 DOI: 10.1016/J.Molcel.2010.02.022  0.789
2010 Mak AB, Ni Z, Hewel JA, Chen GI, Zhong G, Karamboulas K, Blakely K, Smiley S, Marcon E, Roudeva D, Li J, Olsen JB, Wan C, Punna T, Isserlin R, ... ... Gingras AC, et al. A lentiviral functional proteomics approach identifies chromatin remodeling complexes important for the induction of pluripotency. Molecular & Cellular Proteomics : McP. 9: 811-23. PMID 20305087 DOI: 10.1074/Mcp.M000002-Mcp201  0.422
2009 Goudreault M, D'Ambrosio LM, Kean MJ, Mullin MJ, Larsen BG, Sanchez A, Chaudhry S, Chen GI, Sicheri F, Nesvizhskii AI, Aebersold R, Raught B, Gingras AC. A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein. Molecular & Cellular Proteomics : McP. 8: 157-71. PMID 18782753 DOI: 10.1074/Mcp.M800266-Mcp200  0.752
2008 Chen GI, Tisayakorn S, Jorgensen C, D'Ambrosio LM, Goudreault M, Gingras AC. PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4. The Journal of Biological Chemistry. 283: 29273-84. PMID 18715871 DOI: 10.1074/Jbc.M803443200  0.414
2008 Rong L, Livingstone M, Sukarieh R, Petroulakis E, Gingras AC, Crosby K, Smith B, Polakiewicz RD, Pelletier J, Ferraiuolo MA, Sonenberg N. Control of eIF4E cellular localization by eIF4E-binding proteins, 4E-BPs. Rna (New York, N.Y.). 14: 1318-27. PMID 18515545 DOI: 10.1261/Rna.950608  0.561
2007 Gingras AC, Gstaiger M, Raught B, Aebersold R. Analysis of protein complexes using mass spectrometry. Nature Reviews. Molecular Cell Biology. 8: 645-54. PMID 17593931 DOI: 10.1038/Nrm2208  0.736
2007 Chen GI, Gingras AC. Affinity-purification mass spectrometry (AP-MS) of serine/threonine phosphatases. Methods (San Diego, Calif.). 42: 298-305. PMID 17532517 DOI: 10.1016/J.Ymeth.2007.02.018  0.367
2007 Jasavala R, Martinez H, Thumar J, Andaya A, Gingras AC, Eng JK, Aebersold R, Han DK, Wright ME. Identification of putative androgen receptor interaction protein modules: cytoskeleton and endosomes modulate androgen receptor signaling in prostate cancer cells. Molecular & Cellular Proteomics : McP. 6: 252-71. PMID 17052974 DOI: 10.1074/Mcp.M600169-Mcp200  0.507
2007 Raught B, Gingras A. 14 Signaling to Translation Initiation Cold Spring Harbor Monograph Archive. 48: 369-400. DOI: 10.1101/087969767.48.369  0.716
2005 Svitkin YV, Herdy B, Costa-Mattioli M, Gingras AC, Raught B, Sonenberg N. Eukaryotic translation initiation factor 4E availability controls the switch between cap-dependent and internal ribosomal entry site-mediated translation. Molecular and Cellular Biology. 25: 10556-65. PMID 16287867 DOI: 10.1128/Mcb.25.23.10556-10565.2005  0.734
2005 Gingras AC, Caballero M, Zarske M, Sanchez A, Hazbun TR, Fields S, Sonenberg N, Hafen E, Raught B, Aebersold R. A novel, evolutionarily conserved protein phosphatase complex involved in cisplatin sensitivity. Molecular & Cellular Proteomics : McP. 4: 1725-40. PMID 16085932 DOI: 10.1074/Mcp.M500231-Mcp200  0.755
2005 Gingras AC, Aebersold R, Raught B. Advances in protein complex analysis using mass spectrometry. The Journal of Physiology. 563: 11-21. PMID 15611014 DOI: 10.1113/Jphysiol.2004.080440  0.765
2004 Raught B, Peiretti F, Gingras AC, Livingstone M, Shahbazian D, Mayeur GL, Polakiewicz RD, Sonenberg N, Hershey JW. Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. The Embo Journal. 23: 1761-9. PMID 15071500 DOI: 10.1038/Sj.Emboj.7600193  0.755
2004 Gingras AC, Raught B, Sonenberg N. mTOR signaling to translation. Current Topics in Microbiology and Immunology. 279: 169-97. PMID 14560958 DOI: 10.1007/978-3-642-18930-2_11  0.732
2003 Zuberek J, Wyslouch-Cieszynska A, Niedzwiecka A, Dadlez M, Stepinski J, Augustyniak W, Gingras AC, Zhang Z, Burley SK, Sonenberg N, Stolarski R, Darzynkiewicz E. Phosphorylation of eIF4E attenuates its interaction with mRNA 5' cap analogs by electrostatic repulsion: intein-mediated protein ligation strategy to obtain phosphorylated protein. Rna (New York, N.Y.). 9: 52-61. PMID 12554876 DOI: 10.1261/Rna.2133403  0.602
2002 Deng J, Harding HP, Raught B, Gingras AC, Berlanga JJ, Scheuner D, Kaufman RJ, Ron D, Sonenberg N. Activation of GCN2 in UV-irradiated cells inhibits translation. Current Biology : Cb. 12: 1279-86. PMID 12176355 DOI: 10.1016/S0960-9822(02)01037-0  0.745
2002 Niedzwiecka A, Marcotrigiano J, Stepinski J, Jankowska-Anyszka M, Wyslouch-Cieszynska A, Dadlez M, Gingras AC, Mak P, Darzynkiewicz E, Sonenberg N, Burley SK, Stolarski R. Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins. Journal of Molecular Biology. 319: 615-35. PMID 12054859 DOI: 10.1016/S0022-2836(02)00328-5  0.519
2002 Li S, Sonenberg N, Gingras AC, Peterson M, Avdulov S, Polunovsky VA, Bitterman PB. Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. Molecular and Cellular Biology. 22: 2853-61. PMID 11909977 DOI: 10.1128/Mcb.22.8.2853-2861.2002  0.495
2002 Tang SJ, Reis G, Kang H, Gingras AC, Sonenberg N, Schuman EM. A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 99: 467-72. PMID 11756682 DOI: 10.1073/pnas.012605299  0.46
2001 Gingras AC, Raught B, Gygi SP, Niedzwiecka A, Miron M, Burley SK, Polakiewicz RD, Wyslouch-Cieszynska A, Aebersold R, Sonenberg N. Hierarchical phosphorylation of the translation inhibitor 4E-BP1. Genes & Development. 15: 2852-64. PMID 11691836 DOI: 10.1101/Gad.912401  0.803
2001 Tsukiyama-Kohara K, Poulin F, Kohara M, DeMaria CT, Cheng A, Wu Z, Gingras AC, Katsume A, Elchebly M, Spiegelman BM, Harper ME, Tremblay ML, Sonenberg N. Adipose tissue reduction in mice lacking the translational inhibitor 4E-BP1. Nature Medicine. 7: 1128-32. PMID 11590436 DOI: 10.1038/Nm1001-1128  0.689
2001 Gingras AC, Raught B, Sonenberg N. Control of translation by the target of rapamycin proteins. Progress in Molecular and Subcellular Biology. 27: 143-74. PMID 11575159 DOI: 10.1007/978-3-662-09889-9_6  0.775
2001 Raught B, Gingras AC, Sonenberg N. The target of rapamycin (TOR) proteins. Proceedings of the National Academy of Sciences of the United States of America. 98: 7037-44. PMID 11416184 DOI: 10.1073/Pnas.121145898  0.759
2001 Gingras AC, Raught B, Sonenberg N. Regulation of translation initiation by FRAP/mTOR. Genes & Development. 15: 807-26. PMID 11297505 DOI: 10.1101/Gad.887201  0.735
2001 Bhandari BK, Feliers D, Duraisamy S, Stewart JL, Gingras AC, Abboud HE, Choudhury GG, Sonenberg N, Kasinath BS. Insulin regulation of protein translation repressor 4E-BP1, an eIF4E-binding protein, in renal epithelial cells. Kidney International. 59: 866-75. PMID 11231341 DOI: 10.1046/J.1523-1755.2001.059003866.X  0.475
2000 Polunovsky VA, Gingras AC, Sonenberg N, Peterson M, Tan A, Rubins JB, Manivel JC, Bitterman PB. Translational control of the antiapoptotic function of Ras. The Journal of Biological Chemistry. 275: 24776-80. PMID 10811643 DOI: 10.1074/Jbc.M001938200  0.517
2000 Kumar V, Sabatini D, Pandey P, Gingras AC, Majumder PK, Kumar M, Yuan ZM, Carmichael G, Weichselbaum R, Sonenberg N, Kufe D, Kharbanda S. Regulation of the rapamycin and FKBP-target 1/mammalian target of rapamycin and cap-dependent initiation of translation by the c-Abl protein-tyrosine kinase. The Journal of Biological Chemistry. 275: 10779-87. PMID 10753870 DOI: 10.1074/Jbc.275.15.10779  0.582
2000 Raught B, Gingras AC, Gygi SP, Imataka H, Morino S, Gradi A, Aebersold R, Sonenberg N. Serum-stimulated, rapamycin-sensitive phosphorylation sites in the eukaryotic translation initiation factor 4GI. The Embo Journal. 19: 434-44. PMID 10654941 DOI: 10.1093/Emboj/19.3.434  0.797
2000 Raught B, Gingras A, Sonenberg N. 6 Regulation of Ribosomal Recruitment in Eukaryotes Cold Spring Harbor Monograph Archive. 39: 245-293. DOI: 10.1101/087969618.39.245  0.76
1999 Gingras AC, Raught B, Sonenberg N. eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation. Annual Review of Biochemistry. 68: 913-63. PMID 10872469 DOI: 10.1146/Annurev.Biochem.68.1.913  0.777
1999 Takata M, Ogawa W, Kitamura T, Hino Y, Kuroda S, Kotani K, Klip A, Gingras AC, Sonenberg N, Kasuga M. Requirement for Akt (protein kinase B) in insulin-induced activation of glycogen synthase and phosphorylation of 4E-BP1 (PHAS-1). The Journal of Biological Chemistry. 274: 20611-8. PMID 10400692 DOI: 10.1074/Jbc.274.29.20611  0.499
1999 Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK. Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G. Molecular Cell. 3: 707-16. PMID 10394359 DOI: 10.1016/S1097-2765(01)80003-4  0.516
1999 Gingras AC, Gygi SP, Raught B, Polakiewicz RD, Abraham RT, Hoekstra MF, Aebersold R, Sonenberg N. Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism. Genes & Development. 13: 1422-37. PMID 10364159 DOI: 10.1101/Gad.13.11.1422  0.803
1999 Khaleghpour K, Pyronnet S, Gingras AC, Sonenberg N. Translational homeostasis: eukaryotic translation initiation factor 4E control of 4E-binding protein 1 and p70 S6 kinase activities. Molecular and Cellular Biology. 19: 4302-10. PMID 10330171 DOI: 10.1128/Mcb.19.6.4302  0.817
1999 Raught B, Gingras AC. eIF4E activity is regulated at multiple levels. The International Journal of Biochemistry & Cell Biology. 31: 43-57. PMID 10216943 DOI: 10.1016/S1357-2725(98)00131-9  0.753
1999 Rao GN, Madamanchi NR, Lele M, Gadiparthi L, Gingras AC, Eling TE, Sonenberg N. A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells. The Journal of Biological Chemistry. 274: 12925-32. PMID 10212283 DOI: 10.1074/Jbc.274.18.12925  0.509
1999 Gygi SP, Han DK, Gingras AC, Sonenberg N, Aebersold R. Protein analysis by mass spectrometry and sequence database searching: tools for cancer research in the post-genomic era. Electrophoresis. 20: 310-9. PMID 10197438 DOI: 10.1002/(Sici)1522-2683(19990201)20:2<310::Aid-Elps310>3.0.Co;2-M  0.68
1999 Pyronnet S, Imataka H, Gingras AC, Fukunaga R, Hunter T, Sonenberg N. Human eukaryotic translation initiation factor 4G (eIF4G) recruits mnk1 to phosphorylate eIF4E. The Embo Journal. 18: 270-9. PMID 9878069 DOI: 10.1093/Emboj/18.1.270  0.619
1998 Polakiewicz RD, Schieferl SM, Gingras AC, Sonenberg N, Comb MJ. mu-Opioid receptor activates signaling pathways implicated in cell survival and translational control. The Journal of Biological Chemistry. 273: 23534-41. PMID 9722592 DOI: 10.1074/Jbc.273.36.23534  0.508
1998 Svitkin YV, Hahn H, Gingras AC, Palmenberg AC, Sonenberg N. Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus. Journal of Virology. 72: 5811-9. PMID 9621041 DOI: 10.1128/Jvi.72.7.5811-5819.1998  0.537
1998 Pyronnet S, Gingras AC, Bouisson M, Kowalski-Chauvel A, Seva C, Vaysse N, Sonenberg N, Pradayrol L. Gastrin induces phosphorylation of eIF4E binding protein 1 and translation initiation of ornithine decarboxylase mRNA. Oncogene. 16: 2219-27. PMID 9619831 DOI: 10.1038/Sj.Onc.1201748  0.61
1998 Poulin F, Gingras AC, Olsen H, Chevalier S, Sonenberg N. 4E-BP3, a new member of the eukaryotic initiation factor 4E-binding protein family. The Journal of Biological Chemistry. 273: 14002-7. PMID 9593750 DOI: 10.1074/Jbc.273.22.14002  0.7
1998 Rom E, Kim HC, Gingras AC, Marcotrigiano J, Favre D, Olsen H, Burley SK, Sonenberg N. Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein. The Journal of Biological Chemistry. 273: 13104-9. PMID 9582349 DOI: 10.1074/Jbc.273.21.13104  0.58
1998 Sonenberg N, Gingras AC. The mRNA 5' cap-binding protein eIF4E and control of cell growth. Current Opinion in Cell Biology. 10: 268-75. PMID 9561852 DOI: 10.1016/S0955-0674(98)80150-6  0.575
1998 Sonenberg N, Burley SK, Gingras AC. RNA chiropractics. Nature Structural Biology. 5: 172-4. PMID 9501904 DOI: 10.1038/nsb0398-172  0.306
1997 Gingras AC, Sonenberg N. Adenovirus infection inactivates the translational inhibitors 4E-BP1 and 4E-BP2. Virology. 237: 182-6. PMID 9344920 DOI: 10.1006/Viro.1997.8757  0.541
1997 Matsuo H, Li H, McGuire AM, Fletcher CM, Gingras AC, Sonenberg N, Wagner G. Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein. Nature Structural Biology. 4: 717-24. PMID 9302999 DOI: 10.1038/nsb0997-717  0.469
1997 Marcotrigiano J, Gingras AC, Sonenberg N, Burley SK. Cocrystal structure of the messenger RNA 5' cap-binding protein (eIF4E) bound to 7-methyl-GDP. Cell. 89: 951-61. PMID 9200613 DOI: 10.1016/S0092-8674(00)80280-9  0.508
1997 Fleurent M, Gingras AC, Sonenberg N, Meloche S. Angiotensin II stimulates phosphorylation of the translational repressor 4E-binding protein 1 by a mitogen-activated protein kinase-independent mechanism. The Journal of Biological Chemistry. 272: 4006-12. PMID 9020107 DOI: 10.1074/Jbc.272.7.4006  0.571
1996 Whalen SG, Gingras AC, Amankwa L, Mader S, Branton PE, Aebersold R, Sonenberg N. Phosphorylation of eIF-4E on serine 209 by protein kinase C is inhibited by the translational repressers, 4E-binding proteins Journal of Biological Chemistry. 271: 11831-11837. PMID 8662663 DOI: 10.1074/Jbc.271.20.11831  0.653
1996 Gingras AC, Svitkin Y, Belsham GJ, Pause A, Sonenberg N. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus. Proceedings of the National Academy of Sciences of the United States of America. 93: 5578-83. PMID 8643618 DOI: 10.1073/Pnas.93.11.5578  0.546
1996 ROUSSEAU D, GINGRAS A, PAUSE A, SONENBERG N. IDENTIFICATION OF POTENTIAL ANTI-ONCOGENIC PROPERTIES OF elF-4E BINDING PROTEINS 1 AND 2 Biology of the Cell. 88: 69-69. DOI: 10.1016/S0248-4900(97)86843-8  0.514
1994 Pause A, Belsham GJ, Gingras AC, Donzé O, Lin TA, Lawrence JC, Sonenberg N. Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function. Nature. 371: 762-7. PMID 7935836 DOI: 10.1038/371762A0  0.507
Show low-probability matches.