Kenneth T. MacLeod - Publications

Affiliations: 
Physiology University of Edinburgh, Edinburgh, Scotland, United Kingdom 

95 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Francis AJ, Firth JM, Sanchez-Alonso JL, Gorelik J, MacLeod KT. GPER limits adverse changes to Ca signalling and arrhythmogenic activity in ovariectomised guinea pig cardiomyocytes. Frontiers in Physiology. 13: 1023755. PMID 36439245 DOI: 10.3389/fphys.2022.1023755  0.735
2022 Wang BX, Kane C, Nicastro L, King O, Kit-Anan W, Downing B, Deidda G, Couch LS, Pinali C, Mitraki A, MacLeod KT, Terracciano CM. Integrins Increase Sarcoplasmic Reticulum Activity for Excitation-Contraction Coupling in Human Stem Cell-Derived Cardiomyocytes. International Journal of Molecular Sciences. 23. PMID 36142853 DOI: 10.3390/ijms231810940  0.687
2022 MacLeod KT. Changes in cellular Ca and Na regulation during the progression towards heart failure. The Journal of Physiology. PMID 35946572 DOI: 10.1113/JP283082  0.518
2022 Wang BX, Nicastro L, Couch L, Kit-Anan W, Downing B, MacLeod KT, Terracciano CM. Extracellular Vesicles from Human Cardiac Fibroblasts Modulate Calcium Cycling in Human Stem Cell-Derived Cardiomyocytes. Cells. 11. PMID 35406735 DOI: 10.3390/cells11071171  0.636
2021 Bannister ML, MacLeod KT, George CH. Moving in the right direction - elucidating mechanisms of interaction between flecainide and the cardiac ryanodine receptor. British Journal of Pharmacology. PMID 34698387 DOI: 10.1111/bph.15718  0.385
2020 Firth JM, Yang HY, Francis AJ, Islam N, MacLeod KT. The Effect of Estrogen on Intracellular Ca and Na Regulation in Heart Failure. Jacc. Basic to Translational Science. 5: 901-912. PMID 33015413 DOI: 10.1016/J.Jacbts.2020.06.013  0.491
2020 Wright PT, Tsui SF, Francis AJ, MacLeod KT, Marston SB. Approaches to High-Throughput Analysis of Cardiomyocyte Contractility. Frontiers in Physiology. 11: 612. PMID 32733259 DOI: 10.3389/Fphys.2020.00612  0.641
2020 Lyon AR, Babalis D, Morley-Smith AC, Hedger M, Suarez Barrientos A, Foldes G, Couch LS, Chowdhury RA, Tzortzis KN, Peters NS, Rog-Zielinska EA, Yang HY, Welch S, Bowles CT, Rahman Haley S, ... ... Macleod KT, et al. Investigation of the safety and feasibility of AAV1/SERCA2a gene transfer in patients with chronic heart failure supported with a left ventricular assist device - the SERCA-LVAD TRIAL. Gene Therapy. PMID 32669717 DOI: 10.1038/S41434-020-0171-7  0.561
2020 Ching E, Firth JM, Francis AJ, Islam N, Macleod KT. P943The effects of ovariectomy on guinea pig cardiomyocyte intracellular calcium regulation and phosphorylation Ep Europace. 22. DOI: 10.1093/Europace/Euaa162.214  0.363
2020 Francis A, Firth J, Islam N, Gorelik J, MacLeod K. The effect of oestrogen withdrawal on cardiac Ca2+ regulation and the influence of GPER1 European Heart Journal. 41. DOI: 10.1093/ehjci/ehaa946.3599  0.789
2020 Francis AJ, Firth JM, Islam N, Gorelik J, Macleod KT. The Effect of Oestrogen Withdrawal on Ca2+ Regulation and the Influence of GPER1 Biophysical Journal. 118: 403a-404a. DOI: 10.1016/J.Bpj.2019.11.2290  0.765
2019 Ke HY, Yang HS, Francis AJ, Collins TP, Surendran H, Alvarez-Laviada A, Firth JM, MacLeod KT. Changes in cellular Ca and Na regulation during the progression towards heart failure in the guinea pig. The Journal of Physiology. PMID 30811606 DOI: 10.1113/Jp277038  0.798
2018 Wang B, Deidda G, Mitraki A, MacLeod KT, Terracciano CM. P5718Self-assembling arginine-glycine-aspartic acid-containing peptides abbreviate human cardiomyocyte calcium transients and increase sarcoplasmic reticulum contribution to excitation-contraction coupling European Heart Journal. 39. DOI: 10.1093/Eurheartj/Ehy566.P5718  0.564
2018 Firth JM, Yang H, Francis AJ, Alvarez-Laviada A, MacLeod KT. The Effect of Oestrogen on Ca2+ and Na+ Regulation in Heart Failure Biophysical Journal. 114: 617a. DOI: 10.1016/J.Bpj.2017.11.3343  0.789
2017 Sikkel MB, Francis DP, Howard J, Gordon F, Rowlands C, Peters NS, Lyon AR, Harding SE, MacLeod KT. Hierarchical Statistical Techniques are Necessary to Draw Reliable Conclusions from Analysis of Isolated Cardiomyocyte Studies. Cardiovascular Research. PMID 29016722 DOI: 10.1093/Cvr/Cvx151  0.389
2017 Rowlands C, Owen T, Lawal S, Cao S, Pandey S, Yang HY, Song W, Wilkinson R, Alvarez-Laviada A, Gehmlich K, Marston S, MacLeod KT. Age and strain related aberrant Ca(2+) release is associated with sudden cardiac death in the ACTC E99K mouse model of hypertrophic cardiomyopathy. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00244.2017. PMID 28887330 DOI: 10.1152/Ajpheart.00244.2017  0.76
2017 Yang HY, Firth JM, Francis AJ, Alvarez-Laviada A, MacLeod KT. The effect of ovariectomy on intracellular calcium (Ca(2+)) regulation in guinea pig cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00249.2017. PMID 28778911 DOI: 10.1152/Ajpheart.00249.2017  0.808
2017 Shattock MJ, Park KC, Yang HY, Lee AW, Niederer S, MacLeod KT, Winter J. Restitution slope is principally determined by steady-state action potential duration. Cardiovascular Research. PMID 28371805 DOI: 10.1093/Cvr/Cvx063  0.416
2017 Wang B, Terracciano C, Macleod K. Regulation of cardiac excitation-contraction coupling by fibroblasts in health and disease Journal of Molecular and Cellular Cardiology. 112: 161. DOI: 10.1016/J.Yjmcc.2017.07.090  0.561
2017 Yang H, Alvarez-Laviada A, Firth JM, Francis AJ, MacLeod KT. The Effect of Ovariectomy on Calcium (Ca 2+ ) Handling in Guinea Pig Cardiomyocytes Biophysical Journal. 112: 101a. DOI: 10.1016/J.Bpj.2016.11.581  0.791
2016 MacLeod KT. Recent advances in understanding cardiac contractility in health and disease. F1000research. 5: 1770. PMID 27508064 DOI: 10.12688/F1000Research.8661.1  0.558
2016 Bannister ML, Alvarez-Laviada A, Thomas NL, Mason SA, Coleman S, du Plessis CL, Moran AT, Neill-Hall D, Osman H, Bagley MC, MacLeod KT, George CH, Williams AJ. Effect of flecainide derivatives on sarcoplasmic reticulum calcium release suggests a lack of direct action on the cardiac ryanodine receptor. British Journal of Pharmacology. PMID 27237957 DOI: 10.1111/Bph.13521  0.757
2016 Toepfer CN, Sikkel MB, Caorsi V, Vydyanath A, Torre I, Copeland O, Lyon AR, Marston SB, Luther PK, MacLeod KT, West TG, Ferenczi MA. A post-MI power struggle: adaptations in cardiac power occur at the sarcomere level alongside MyBP-C and RLC phosphorylation. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00899.2015. PMID 27233767 DOI: 10.1152/Ajpheart.00899.2015  0.315
2015 Sikkel MB, Kumar S, Maioli V, Rowlands C, Gordon F, Harding SE, Lyon AR, MacLeod KT, Dunsby C. High speed sCMOS-based oblique plane microscopy applied to the study of calcium dynamics in cardiac myocytes. Journal of Biophotonics. PMID 26488431 DOI: 10.1002/Jbio.201500193  0.357
2015 Bannister ML, Thomas NL, Sikkel MB, Mukherjee S, Maxwell C, MacLeod KT, George CH, Williams AJ. The mechanism of flecainide action in CPVT does not involve a direct effect on RyR2. Circulation Research. 116: 1324-35. PMID 25648700 DOI: 10.1161/Circresaha.116.305347  0.474
2014 Taggart MJ, Hume R, Lartey J, Johnson M, Tong WC, Macleod KT. Cardiac remodelling during pregnancy: whither the guinea pig? Cardiovascular Research. 104: 226-7. PMID 25155044 DOI: 10.1093/Cvr/Cvu198  0.331
2014 Dias P, Desplantez T, El-Harasis MA, Chowdhury RA, Ullrich ND, Cabestrero de Diego A, Peters NS, Severs NJ, MacLeod KT, Dupont E. Characterisation of connexin expression and electrophysiological properties in stable clones of the HL-1 myocyte cell line. Plos One. 9: e90266. PMID 24587307 DOI: 10.1371/Journal.Pone.0090266  0.341
2014 Sikkel MB, Hayward C, MacLeod KT, Harding SE, Lyon AR. SERCA2a gene therapy in heart failure: an anti-arrhythmic positive inotrope. British Journal of Pharmacology. 171: 38-54. PMID 24138023 DOI: 10.1111/Bph.12472  0.503
2014 Ke H, Collins TP, Alvarez-Laviada A, Rowlands C, MacLeod KT. Na/K ATPase Function Declines Before Changes to Calcium Handling in a Guinea-Pig Model of Progressive Heart Failure Biophysical Journal. 106: 763a. DOI: 10.1016/J.Bpj.2013.11.4196  0.715
2014 Al-khayatt BM, Sikkel MB, Laviada AA, Ke H, Rowlands C, Macleod KT. Ranolazine Reduces Arrhythmogenic Calcium Waves in Ventricular Cardiomyocytes Biophysical Journal. 106: 721a. DOI: 10.1016/J.Bpj.2013.11.3982  0.383
2014 Toepfer C, Sikkel M, Caorsi V, Copeland O, Martinez IT, West T, Marston S, Luther P, Lyon A, Macleod K, Ferenczi M. Effects of Chronic Myocardial Infarction on Cardiac Muscle Performance and Structure In-Vivo and In-Vitro Biophysical Journal. 106: 343a-344a. DOI: 10.1016/J.Bpj.2013.11.1963  0.34
2014 Alvarez-Laviada A, Sikkel M, Al-khayatt B, MacLeod KT. Effects of Flecainide and Ranolazine on Intracellular Calcium Handling and Sarcolemmal Sodium Current Biophysical Journal. 106: 324a. DOI: 10.1016/J.Bpj.2013.11.1865  0.776
2014 Rowlands CT, Marston SB, MacLeod KT. Calcium Handling is Altered in the Actc E99K Transgenic Mouse Model of Hypertrophic Cardiomyopathy Biophysical Journal. 106: 323a. DOI: 10.1016/J.Bpj.2013.11.1863  0.467
2013 Sikkel MB, Collins TP, Rowlands C, Shah M, O'Gara P, Williams AJ, Harding SE, Lyon AR, MacLeod KT. Triple mode of action of flecainide in catecholaminergic polymorphic ventricular tachycardia: reply. Cardiovascular Research. 98: 327-8. PMID 23536607 DOI: 10.1093/Cvr/Cvt068  0.569
2013 Toepfer C, Caorsi V, Kampourakis T, Sikkel MB, West TG, Leung MC, Al-Saud SA, MacLeod KT, Lyon AR, Marston SB, Sellers JR, Ferenczi MA. Myosin regulatory light chain (RLC) phosphorylation change as a modulator of cardiac muscle contraction in disease. The Journal of Biological Chemistry. 288: 13446-54. PMID 23530050 DOI: 10.1074/Jbc.M113.455444  0.326
2013 Sikkel MB, Collins TP, Rowlands C, Shah M, O'Gara P, Williams AJ, Harding SE, Lyon AR, MacLeod KT. Flecainide reduces Ca(2+) spark and wave frequency via inhibition of the sarcolemmal sodium current. Cardiovascular Research. 98: 286-96. PMID 23334259 DOI: 10.1093/Cvr/Cvt012  0.457
2013 Sikkel M, Rowlands C, Harding S, Lyon A, MacLeod K. 221 REDUCING SARCOLEMMAL SODIUM CURRENT DECREASES SPONTANEOUS SR CA2+ RELEASE Heart. 99: A120.1-A120. DOI: 10.1136/Heartjnl-2013-304019.221  0.524
2012 Lyon AR, Nikolaev VO, Miragoli M, Sikkel MB, Paur H, Benard L, Hulot JS, Kohlbrenner E, Hajjar RJ, Peters NS, Korchev YE, Macleod KT, Harding SE, Gorelik J. Plasticity of surface structures and β(2)-adrenergic receptor localization in failing ventricular cardiomyocytes during recovery from heart failure. Circulation. Heart Failure. 5: 357-65. PMID 22456061 DOI: 10.1161/Circheartfailure.111.964692  0.695
2012 Kumarswamy R, Lyon AR, Volkmann I, Mills AM, Bretthauer J, Pahuja A, Geers-Knörr C, Kraft T, Hajjar RJ, Macleod KT, Harding SE, Thum T. SERCA2a gene therapy restores microRNA-1 expression in heart failure via an Akt/FoxO3A-dependent pathway. European Heart Journal. 33: 1067-75. PMID 22362515 DOI: 10.1093/Eurheartj/Ehs043  0.371
2011 Lyon AR, Bannister ML, Collins T, Pearce E, Sepehripour AH, Dubb SS, Garcia E, O'Gara P, Liang L, Kohlbrenner E, Hajjar RJ, Peters NS, Poole-Wilson PA, Macleod KT, Harding SE. SERCA2a gene transfer decreases sarcoplasmic reticulum calcium leak and reduces ventricular arrhythmias in a model of chronic heart failure. Circulation. Arrhythmia and Electrophysiology. 4: 362-72. PMID 21406682 DOI: 10.1161/Circep.110.961615  0.448
2009 Mason SA, MacLeod KT. Cardiac action potential duration and calcium regulation in males and females. Biochemical and Biophysical Research Communications. 388: 565-70. PMID 19682977 DOI: 10.1016/J.Bbrc.2009.08.050  0.538
2009 Kumar S, Hall RJ, Mani AR, Moore KP, Camici PG, Rimoldi OE, Williams AJ, Macleod KT. Myocardial stunning is associated with impaired calcium uptake by sarcoplasmic reticulum. Biochemical and Biophysical Research Communications. 387: 77-82. PMID 19559670 DOI: 10.1016/J.Bbrc.2009.06.115  0.389
2009 Lyon AR, MacLeod KT, Zhang Y, Garcia E, Kanda GK, Lab MJ, Korchev YE, Harding SE, Gorelik J. Loss of T-tubules and other changes to surface topography in ventricular myocytes from failing human and rat heart Proceedings of the National Academy of Sciences of the United States of America. 106: 6854-6859. PMID 19342485 DOI: 10.1073/Pnas.0809777106  0.718
2008 Ullrich ND, Krust A, Collins P, MacLeod KT. Genomic deletion of estrogen receptors ERalpha and ERbeta does not alter estrogen-mediated inhibition of Ca2+ influx and contraction in murine cardiomyocytes. American Journal of Physiology. Heart and Circulatory Physiology. 294: H2421-7. PMID 18441199 DOI: 10.1152/Ajpheart.01225.2007  0.392
2008 Lyon A, Gorelik J, Dubb S, Macleod K, Poole-Wilson P, Harding S. Surface morphology and calcium control in myocytes from a rat MI model of heart failure Journal of Molecular and Cellular Cardiology. 44: 750. DOI: 10.1016/J.Yjmcc.2008.02.094  0.699
2008 Lyon A, Sepehripour A, Dubb S, Macleod K, Poole-Wilson P, Peters N, Harding S. Heterogeneous SERCA2a transfection reduces ventricular arrhythmias in the rat model of heart failure Journal of Molecular and Cellular Cardiology. 44: 714-715. DOI: 10.1016/J.Yjmcc.2008.02.010  0.351
2007 Ullrich ND, Koschak A, MacLeod KT. Oestrogen directly inhibits the cardiovascular L-type Ca2+ channel Cav1.2. Biochemical and Biophysical Research Communications. 361: 522-7. PMID 17662243 DOI: 10.1016/J.Bbrc.2007.07.054  0.535
2006 Tolmachov O, Ma YL, Themis M, Patel P, Spohr H, Macleod KT, Ullrich ND, Kienast Y, Coutelle C, Peters NS. Overexpression of connexin 43 using a retroviral vector improves electrical coupling of skeletal myoblasts with cardiac myocytes in vitro. Bmc Cardiovascular Disorders. 6: 25. PMID 16756651 DOI: 10.1186/1471-2261-6-25  0.347
2006 McMahon AC, Naqvi RU, Hurst MJ, Raine AE, MacLeod KT. Diastolic dysfunction and abnormality of the Na+/Ca2+ exchanger in single uremic cardiac myocytes. Kidney International. 69: 846-51. PMID 16518344 DOI: 10.1038/sj.ki.5000193  0.51
2005 Liew R, Stagg MA, MacLeod KT, Collins P. The red wine polyphenol, resveratrol, exerts acute direct actions on guinea-pig ventricular myocytes. European Journal of Pharmacology. 519: 1-8. PMID 16102748 DOI: 10.1016/J.Ejphar.2005.06.017  0.548
2004 Stagg MA, Malik AH, MacLeod KT, Terracciano CM. The effects of overexpression of the Na+/Ca2+ exchanger on calcium regulation in hypertrophied mouse cardiac myocytes. Cell Calcium. 36: 111-8. PMID 15193859 DOI: 10.1016/J.Ceca.2004.01.001  0.747
2004 Liew R, Stagg MA, MacLeod KT, Collins P. Raloxifene acutely suppresses ventricular myocyte contractility through inhibition of the L-type calcium current. British Journal of Pharmacology. 142: 89-96. PMID 15023859 DOI: 10.1016/S0735-1097(03)82195-2  0.563
2004 Liew R, Stagg MA, MacLeod KT, Collins P. Acute actions of 3 alpha-hydroxy-tibolone on factors influencing contraction in guinea-pig ventricular myocytes. European Journal of Pharmacology. 484: 141-5. PMID 14744597 DOI: 10.1016/J.Ejphar.2003.11.020  0.428
2004 Liew R, Stagg MA, Chan J, Collins P, MacLeod KT. Gender determines the acute actions of genistein on intracellular calcium regulation in the guinea-pig heart. Cardiovascular Research. 61: 66-76. PMID 14732203 DOI: 10.1016/J.Cardiores.2003.10.006  0.392
2003 Liew R, Macleod KT, Collins P. Novel stimulatory actions of the phytoestrogen genistein: effects on the gain of cardiac excitation-contraction coupling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1307-9. PMID 12759336 DOI: 10.1096/Fj.02-0760Fje  0.598
2003 Liew R, Williams JK, Collins P, MacLeod KT. Soy-derived isoflavones exert opposing actions on Guinea pig ventricular myocytes. The Journal of Pharmacology and Experimental Therapeutics. 304: 985-93. PMID 12604673 DOI: 10.1124/Jpet.102.042986  0.512
2003 SCOOTE M, HARDING S, MACLEOD K, WILLIAMS A. 330 Calcium sensitivity characteristics of the cardiac intracellular calcium release channel (ryanodine receptor) following chronic exposure to excessive circulating catecholamines European Journal of Heart Failure Supplements. 2: 62. DOI: 10.1016/S1567-4215(03)90190-1  0.367
2003 Liew R, Stagg M, Collins P, MacLeod KT. Sex differences in the response of cardiac myocytes to the phytoestrogen, Genistein Journal of the American College of Cardiology. 41: 254. DOI: 10.1016/S0735-1097(03)82194-0  0.322
2002 Ranu HK, Terracciano CM, Davia K, Bernobich E, Chaudhri B, Robinson SE, Bin Kang Z, Hajjar RJ, MacLeod KT, Harding SE. Effects of Na(+)/Ca(2+)-exchanger overexpression on excitation-contraction coupling in adult rabbit ventricular myocytes. Journal of Molecular and Cellular Cardiology. 34: 389-400. PMID 11991729 DOI: 10.1006/Jmcc.2001.1521  0.728
2002 MacLeod KT. Pumps and leaks in the heart. The Journal of Physiology. 539: 1. PMID 11850496 DOI: 10.1113/Jphysiol.2002.015586  0.545
2001 Terracciano CM, MacLeod KT. Overexpression of the Na/Ca exchanger and reduced SERCa function. Cardiovascular Research. 50: 167-9. PMID 11345943 DOI: 10.1016/S0008-6363(01)00235-8  0.7
2001 Davia K, Bernobich E, Ranu HK, del Monte F, Terracciano CM, MacLeod KT, Adamson DL, Chaudhri B, Hajjar RJ, Harding SE. SERCA2A overexpression decreases the incidence of aftercontractions in adult rabbit ventricular myocytes. Journal of Molecular and Cellular Cardiology. 33: 1005-15. PMID 11343422 DOI: 10.1006/Jmcc.2001.1368  0.621
2001 Naqvi RU, Tweedie D, MacLeod KT. Evidence for the action potential mediating the changes to contraction observed in cardiac hypertrophy in the rabbit. International Journal of Cardiology. 77: 189-206. PMID 11182183 DOI: 10.1016/S0167-5273(00)00421-6  0.591
2001 Milnes JT, MacLeod KT. Reduced ryanodine receptor to dihydropyridine receptor ratio may underlie slowed contraction in a rabbit model of left ventricular cardiac hypertrophy. Journal of Molecular and Cellular Cardiology. 33: 473-85. PMID 11181016 DOI: 10.1006/Jmcc.2000.1320  0.498
2001 Boateng SY, Naqvi RU, Koban MU, Yacoub MH, MacLeod KT, Boheler KR. Low-dose ramipril treatment improves relaxation and calcium cycling after established cardiac hypertrophy. American Journal of Physiology. Heart and Circulatory Physiology. 280: H1029-38. PMID 11179044 DOI: 10.1152/Ajpheart.2001.280.3.H1029  0.585
2001 Terracciano CM, Philipson KD, MacLeod KT. Overexpression of the Na(+)/Ca(2+) exchanger and inhibition of the sarcoplasmic reticulum Ca(2+)-ATPase in ventricular myocytes from transgenic mice. Cardiovascular Research. 49: 38-47. PMID 11121794 DOI: 10.1016/S0008-6363(00)00205-4  0.725
2000 Egdell RM, Milnes JT, MacLeod KT. The role of L-type calcium current in the generation of repolarization-induced contraction in cardiac myocytes. Cardiovascular Research. 48: 59-67. PMID 11033108 DOI: 10.1016/S0008-6363(00)00148-6  0.369
2000 Egdell RM, De Souza AI, Macleod KT. Relative importance of SR load and cytoplasmic calcium concentration in the genesis of aftercontractions in cardiac myocytes. Cardiovascular Research. 47: 769-77. PMID 10974225 DOI: 10.1016/S0008-6363(00)00147-4  0.388
2000 Tweedie D, Harding SE, MacLeod KT. Sarcoplasmic reticulum Ca content, sarcolemmal Ca influx and the genesis of arrhythmias in isolated guinea-pig cardiomyocytes. Journal of Molecular and Cellular Cardiology. 32: 261-72. PMID 10722802 DOI: 10.1006/Jmcc.1999.1070  0.575
2000 Egdell RM, MacLeod KT. Calcium extrusion during aftercontractions in cardiac myocytes: the role of the sodium-calcium exchanger in the generation of the transient inward current. Journal of Molecular and Cellular Cardiology. 32: 85-93. PMID 10652193 DOI: 10.1006/Jmcc.1999.1056  0.373
1998 Terracciano CM, Souza AI, Philipson KD, MacLeod KT. Na+-Ca2+ exchange and sarcoplasmic reticular Ca2+ regulation in ventricular myocytes from transgenic mice overexpressing the Na+-Ca2+ exchanger. The Journal of Physiology. 512: 651-67. PMID 9769411 DOI: 10.1111/J.1469-7793.1998.651Bd.X  0.733
1998 Mochizuki S, MacLeod KT. Effects of hypoxia and metabolic inhibition on increases in intracellular Ca2+ concentration induced by Na+/Ca2+ exchange in isolated guinea-pig cardiac myocytes. Journal of Molecular and Cellular Cardiology. 29: 2979-87. PMID 9405173 DOI: 10.1006/Jmcc.1997.0542  0.558
1997 Wyatt CN, Campbell V, Brodbeck J, Brice NL, Page KM, Berrow NS, Brickley K, Terracciano CM, Naqvi RU, MacLeod KT, Dolphin AC. Voltage-dependent binding and calcium channel current inhibition by an anti-alpha 1D subunit antibody in rat dorsal root ganglion neurones and guinea-pig myocytes. The Journal of Physiology. 502: 307-19. PMID 9263912 DOI: 10.1111/J.1469-7793.1997.307Bk.X  0.587
1997 Tweedie D, O'Gara P, Harding SE, MacLeod KT. The effect of alterations to action potential duration on beta-adrenoceptor-mediated aftercontractions in human and guinea-pig ventricular myocytes. Journal of Molecular and Cellular Cardiology. 29: 1457-67. PMID 9201630 DOI: 10.1006/Jmcc.1997.0385  0.347
1997 Terracciano CM, MacLeod KT. Effects of lactate on the relative contribution of Ca2+ extrusion mechanisms to relaxation in guinea-pig ventricular myocytes. The Journal of Physiology. 500: 557-70. PMID 9161975 DOI: 10.1113/Jphysiol.1997.Sp022042  0.72
1997 Terracciano CM, MacLeod KT. Measurements of Ca2+ entry and sarcoplasmic reticulum Ca2+ content during the cardiac cycle in guinea pig and rat ventricular myocytes. Biophysical Journal. 72: 1319-26. PMID 9138577 DOI: 10.1016/S0006-3495(97)78778-2  0.728
1997 Terracciano CM, Tweedie D, MacLeod KT. The effects of changes to action potential duration on the calcium content of the sarcoplasmic reticulum in isolated guinea-pig ventricular myocytes. PflüGers Archiv : European Journal of Physiology. 433: 542-4. PMID 9082328 DOI: 10.1007/S004240050312  0.652
1996 Terracciano CM, MacLeod KT. Reloading of Ca(2+)-depleted sarcoplasmic reticulum during rest in guinea pig ventricular myocytes. The American Journal of Physiology. 271: H1814-22. PMID 8945896 DOI: 10.1152/Ajpheart.1996.271.5.H1814  0.717
1995 Harding SE, MacLeod KT, Davies CH, Wynne DG, Poole-Wilson PA. Abnormalities of the myocytes in ischaemic cardiomyopathy. European Heart Journal. 16: 74-81. PMID 8829961 DOI: 10.1093/Eurheartj/16.Suppl_I.74  0.451
1995 Seki S, MacLeod KT. Effects of anoxia on intracellular Ca2+ and contraction in isolated guinea pig cardiac myocytes American Journal of Physiology-Heart and Circulatory Physiology. 268. PMID 7900858 DOI: 10.1152/Ajpheart.1995.268.3.H1045  0.48
1995 Terracciano CM, Naqvi RU, MacLeod KT. Effects of rest interval on the release of calcium from the sarcoplasmic reticulum in isolated guinea pig ventricular myocytes. Circulation Research. 77: 354-60. PMID 7614721 DOI: 10.1161/01.Res.77.2.354  0.707
1994 Naqvi RU, del Monte F, O'Gara P, Harding SE, MacLeod KT. Characteristics of myocytes isolated from hearts of renovascular hypertensive guinea pigs. The American Journal of Physiology. 266: H1886-95. PMID 8203588 DOI: 10.1152/Ajpheart.1994.266.5.H1886  0.543
1994 Terracciano CM, MacLeod KT. Effects of acidosis on Na+/Ca2+ exchange and consequences for relaxation in guinea pig cardiac myocytes. The American Journal of Physiology. 267: H477-87. PMID 8067399  0.665
1994 Naqvi RU, Macleod KT. Effect of hypertrophy on mechanisms of relaxation in isolated cardiac myocytes from guinea pig. The American Journal of Physiology. 267: H1851-61. PMID 7977815 DOI: 10.1152/Ajpheart.1994.267.5.H1851  0.573
1994 Jiang C, Mochizuki S, Poole-Wilson PA, Harding SE, MacLeod KT. Effect of lemakalim on action potentials, intracellular calcium, and contraction in guinea pig and human cardiac myocytes. Cardiovascular Research. 28: 851-7. PMID 7923291 DOI: 10.1093/Cvr/28.6.851  0.486
1992 MacLeod KT, Harding SE. Effects of phorbol ester on contraction, intracellular pH and intracellular Ca2+ in isolated mammalian ventricular myocytes. The Journal of Physiology. 444: 481-98. PMID 1822559 DOI: 10.1113/Jphysiol.1991.Sp018889  0.47
1992 Jiang C, Poole-Wilson PA, Sarrel PM, Mochizuki S, Collins P, MacLeod KT. Effect of 17 beta-oestradiol on contraction, Ca2+ current and intracellular free Ca2+ in guinea-pig isolated cardiac myocytes. British Journal of Pharmacology. 106: 739-45. PMID 1504758 DOI: 10.1111/J.1476-5381.1992.Tb14403.X  0.498
1992 Naqvi RU, Poole-Wilson PA, MacLeod KT. Ca++-cycling in hypertrophied cardiac myocytes Journal of Molecular and Cellular Cardiology. 24. DOI: 10.1016/0022-2828(92)91673-S  0.544
1992 Jiang C, Mochizuki S, Poole-Wilson PA, MacLeod KT. Lemakalim attenuates action potential duration (APD) and intracellular Ca2+ ([Ca2+]i) in guinea-pig and human ventricular myocytes Journal of Molecular and Cellular Cardiology. 24: 147. DOI: 10.1016/0022-2828(92)90466-D  0.565
1991 Harding SE, MacLeod KT, Jones SM, Vescovo G, Poole-Wilson PA. Contractile responses of myocytes isolated from patients with cardiomyopathy. European Heart Journal. 44-8. PMID 1915458 DOI: 10.1093/Eurheartj/12.Suppl_D.44  0.401
1991 Sitsapesan R, Montgomery RA, MacLeod KT, Williams AJ. Sheep cardiac sarcoplasmic reticulum calcium-release channels: modification of conductance and gating by temperature. The Journal of Physiology. 434: 469-88. PMID 1850797 DOI: 10.1113/Jphysiol.1991.Sp018481  0.331
1990 MacLeod KT. Effects of hypoxia and metabolic inhibition on the intracellular sodium activity of mammalian ventricular muscle. The Journal of Physiology. 416: 455-68. PMID 2558176 DOI: 10.1113/Jphysiol.1989.Sp017771  0.361
1987 MacLeod KT, Bers DM. Effects of rest duration and ryanodine on changes of extracellular [Ca] in cardiac muscle from rabbits. The American Journal of Physiology. 253: C398-407. PMID 3631248 DOI: 10.1152/Ajpcell.1987.253.3.C398  0.487
1987 Bers DM, Bridge JH, MacLeod KT. The mechanism of ryanodine action in rabbit ventricular muscle evaluated with Ca-selective microelectrodes and rapid cooling contractures. Canadian Journal of Physiology and Pharmacology. 65: 610-8. PMID 3607606 DOI: 10.1139/Y87-103  0.472
1985 Ellis D, MacLeod KT. Sodium-dependent control of intracellular pH in Purkinje fibres of sheep heart. The Journal of Physiology. 359: 81-105. PMID 3923187  0.499
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