David Leib - Publications

Affiliations: 
University of California, San Francisco, San Francisco, CA 

99 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen Y, Jang H, Spratt PWE, Kosar S, Taylor DE, Essner RA, Bai L, Leib DE, Kuo TW, Lin YC, Patel M, Subkhangulova A, Kato S, Feinberg EH, Bender KJ, et al. Soma-Targeted Imaging of Neural Circuits by Ribosome Tethering. Neuron. PMID 32574560 DOI: 10.1016/j.neuron.2020.05.005  1
2017 Katzenell S, Cabrera JR, North BJ, Leib DA. Correction to: Isolation, Purification, and Culture of Primary Murine Sensory Neurons. Methods in Molecular Biology (Clifton, N.J.). 1656: E3. PMID 30350167 DOI: 10.1007/978-1-4939-7237-1_19  0.48
2017 Leib DE, Zimmerman CA, Poormoghaddam A, Huey EL, Ahn JS, Lin YC, Tan CL, Chen Y, Knight ZA. The Forebrain Thirst Circuit Drives Drinking through Negative Reinforcement. Neuron. 96: 1272-1281.e4. PMID 29268095 DOI: 10.1016/j.neuron.2017.11.041  1
2017 Katzenell S, Cabrera JR, North BJ, Leib DA. Isolation, Purification, and Culture of Primary Murine Sensory Neurons. Methods in Molecular Biology (Clifton, N.J.). 1656: 229-251. PMID 28808974 DOI: 10.1007/978-1-4939-7237-1_15  0.48
2017 Zimmerman CA, Leib DE, Knight ZA. Neural circuits underlying thirst and fluid homeostasis. Nature Reviews. Neuroscience. PMID 28638120 DOI: 10.1038/nrn.2017.71  1
2016 Leib DE, Zimmerman CA, Knight ZA. Thirst. Current Biology : Cb. 26: R1260-R1265. PMID 27997832 DOI: 10.1016/j.cub.2016.11.019  1
2016 Parker ZM, Pasieka TJ, Parker GA, Leib DA. Immune and non-immune compartment-specific IFN responses are critical determinants of HSV-induced generalized infections and acute liver failure. Journal of Virology. PMID 27681121 DOI: 10.1128/JVI.01473-16  0.48
2016 Tan CL, Cooke EK, Leib DE, Lin YC, Daly GE, Zimmerman CA, Knight ZA. Warm-Sensitive Neurons that Control Body Temperature. Cell. PMID 27616062 DOI: 10.1016/j.cell.2016.08.028  0.92
2016 Leib DE, Knight ZA. Rapid Sensing of Dietary Amino Acid Deficiency Does Not Require GCN2. Cell Reports. 16: 2051-2. PMID 27558825 DOI: 10.1016/j.celrep.2016.08.022  1
2016 Rosato PC, Katzenell S, Pesola JM, North B, Coen DM, Leib DA. Neuronal IFN signaling is dispensable for the establishment of HSV-1 latency. Virology. 497: 323-327. PMID 27518540 DOI: 10.1016/j.virol.2016.06.016  0.48
2016 Zimmerman CA, Lin YC, Leib DE, Guo L, Huey EL, Daly GE, Chen Y, Knight ZA. Thirst neurons anticipate the homeostatic consequences of eating and drinking. Nature. PMID 27487211 DOI: 10.1038/nature18950  0.92
2016 Katzenell S, Leib DA. Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons. Journal of Virology. PMID 26912623 DOI: 10.1128/JVI.02908-15  0.48
2015 Leib DE, Knight ZA. Re-examination of Dietary Amino Acid Sensing Reveals a GCN2-Independent Mechanism. Cell Reports. 13: 1081-9. PMID 26526991 DOI: 10.1016/j.celrep.2015.09.055  1
2015 Jiang Y, Yin X, Stuart PM, Leib DA. Dendritic Cell Autophagy Contributes to Herpes Simplex Virus-Driven Stromal Keratitis and Immunopathology. Mbio. 6. PMID 26507231 DOI: 10.1128/mBio.01426-15  0.48
2015 Parker ZM, Murphy AA, Leib DA. Role of the DNA Sensor STING in Protection from Lethal Infection following Corneal and Intracerebral Challenge with Herpes Simplex Virus 1. Journal of Virology. 89: 11080-91. PMID 26311879 DOI: 10.1128/JVI.00954-15  0.48
2015 Rosato PC, Leib DA. Neurons versus herpes simplex virus: the innate immune interactions that contribute to a host-pathogen standoff. Future Virology. 10: 699-714. PMID 26213562 DOI: 10.2217/fvl.15.45  0.48
2015 Rosato PC, Leib DA. Neuronal Interferon Signaling Is Required for Protection against Herpes Simplex Virus Replication and Pathogenesis. Plos Pathogens. 11: e1005028. PMID 26153886 DOI: 10.1371/journal.ppat.1005028  0.48
2014 Torres IM, Patankar YR, Shabaneh TB, Dolben E, Hogan DA, Leib DA, Berwin BL. Acidosis potentiates the host proinflammatory interleukin-1β response to Pseudomonas aeruginosa infection. Infection and Immunity. 82: 4689-97. PMID 25156732 DOI: 10.1128/IAI.02024-14  0.48
2014 Rosato PC, Leib DA. Intrinsic innate immunity fails to control herpes simplex virus and vesicular stomatitis virus replication in sensory neurons and fibroblasts. Journal of Virology. 88: 9991-10001. PMID 24942587 DOI: 10.1128/JVI.01462-14  0.48
2014 Pan D, Flores O, Umbach JL, Pesola JM, Bentley P, Rosato PC, Leib DA, Cullen BR, Coen DM. A neuron-specific host microRNA targets herpes simplex virus-1 ICP0 expression and promotes latency. Cell Host & Microbe. 15: 446-56. PMID 24721573 DOI: 10.1016/j.chom.2014.03.004  0.48
2014 Katzenell S, Chen Y, Parker ZM, Leib DA. The differential interferon responses of two strains of Stat1-deficient mice do not alter susceptibility to HSV-1 and VSV in vivo. Virology. 450: 350-4. PMID 24503098 DOI: 10.1016/j.virol.2013.12.015  0.48
2013 Murphy AA, Rosato PC, Parker ZM, Khalenkov A, Leib DA. Synergistic control of herpes simplex virus pathogenesis by IRF-3, and IRF-7 revealed through non-invasive bioluminescence imaging. Virology. 444: 71-9. PMID 23777662 DOI: 10.1016/j.virol.2013.05.034  0.48
2013 Radtke K, English L, Rondeau C, Leib D, Lippé R, Desjardins M. Inhibition of the host translation shutoff response by herpes simplex virus 1 triggers nuclear envelope-derived autophagy. Journal of Virology. 87: 3990-7. PMID 23365427 DOI: 10.1128/JVI.02974-12  0.48
2012 Leib DA. Herpes simplex virus encephalitis: toll-free access to the brain. Cell Host & Microbe. 12: 731-2. PMID 23245315 DOI: 10.1016/j.chom.2012.11.005  0.48
2012 Gobeil PA, Leib DA. Herpes simplex virus γ34.5 interferes with autophagosome maturation and antigen presentation in dendritic cells. Mbio. 3: e00267-12. PMID 23073763 DOI: 10.1128/mBio.00267-12  0.48
2012 Yordy B, Iijima N, Huttner A, Leib D, Iwasaki A. A neuron-specific role for autophagy in antiviral defense against herpes simplex virus. Cell Host & Microbe. 12: 334-45. PMID 22980330 DOI: 10.1016/j.chom.2012.07.013  0.48
2012 Pasieka TJ, Menachery VD, Rosato PC, Leib DA. Corneal replication is an interferon response-independent bottleneck for virulence of herpes simplex virus 1 in the absence of virion host shutoff. Journal of Virology. 86: 7692-5. PMID 22553331 DOI: 10.1128/JVI.00761-12  0.48
2012 Morris JE, Zobell S, Yin XT, Zakeri H, Summers BC, Leib DA, Stuart PM. Mice with mutations in Fas and Fas ligand demonstrate increased herpetic stromal keratitis following corneal infection with HSV-1. Journal of Immunology (Baltimore, Md. : 1950). 188: 793-9. PMID 22156346 DOI: 10.4049/jimmunol.1102251  0.48
2011 Pasieka TJ, Cilloniz C, Carter VS, Rosato P, Katze MG, Leib DA. Functional genomics reveals an essential and specific role for Stat1 in protection of the central nervous system following herpes simplex virus corneal infection. Journal of Virology. 85: 12972-81. PMID 21994441 DOI: 10.1128/JVI.06032-11  0.48
2011 Pasieka TJ, Collins L, O'Connor MA, Chen Y, Parker ZM, Berwin BL, Piwnica-Worms DR, Leib DA. Bioluminescent imaging reveals divergent viral pathogenesis in two strains of Stat1-deficient mice, and in αßγ interferon receptor-deficient mice. Plos One. 6: e24018. PMID 21915277 DOI: 10.1371/journal.pone.0024018  0.48
2010 Menachery VD, Pasieka TJ, Leib DA. Interferon regulatory factor 3-dependent pathways are critical for control of herpes simplex virus type 1 central nervous system infection. Journal of Virology. 84: 9685-94. PMID 20660188 DOI: 10.1128/JVI.00706-10  0.48
2009 Menachery VD, Leib DA. Control of herpes simplex virus replication is mediated through an interferon regulatory factor 3-dependent pathway. Journal of Virology. 83: 12399-406. PMID 19759149 DOI: 10.1128/JVI.00888-09  0.48
2009 Leib DA, Alexander DE, Cox D, Yin J, Ferguson TA. Interaction of ICP34.5 with Beclin 1 modulates herpes simplex virus type 1 pathogenesis through control of CD4+ T-cell responses. Journal of Virology. 83: 12164-71. PMID 19759141 DOI: 10.1128/JVI.01676-09  0.48
2009 English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, Alexander D, Leib D, Norbury C, Lippé R, Desjardins M. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nature Immunology. 10: 480-7. PMID 19305394 DOI: 10.1038/ni.1720  0.48
2009 Pasieka TJ, Cilloniz C, Lu B, Teal TH, Proll SC, Katze MG, Leib DA. Host responses to wild-type and attenuated herpes simplex virus infection in the absence of Stat1. Journal of Virology. 83: 2075-87. PMID 19109391 DOI: 10.1128/JVI.02007-08  0.48
2008 Keadle TL, Alexander DE, Leib DA, Stuart PM. Interferon gamma is not required for recurrent herpetic stromal keratitis. Virology. 380: 46-51. PMID 18755490 DOI: 10.1016/j.virol.2008.07.018  0.48
2008 Pasieka TJ, Lu B, Leib DA. Enhanced pathogenesis of an attenuated herpes simplex virus for mice lacking Stat1. Journal of Virology. 82: 6052-5. PMID 18400863 DOI: 10.1128/JVI.00297-08  0.48
2008 Pasieka TJ, Lu B, Crosby SD, Wylie KM, Morrison LA, Alexander DE, Menachery VD, Leib DA. Herpes simplex virus virion host shutoff attenuates establishment of the antiviral state. Journal of Virology. 82: 5527-35. PMID 18367525 DOI: 10.1128/JVI.02047-07  0.48
2008 Alexander DE, Leib DA. Xenophagy in herpes simplex virus replication and pathogenesis. Autophagy. 4: 101-3. PMID 18000391  0.48
2007 Orvedahl A, Alexander D, Tallóczy Z, Sun Q, Wei Y, Zhang W, Burns D, Leib DA, Levine B. HSV-1 ICP34.5 confers neurovirulence by targeting the Beclin 1 autophagy protein. Cell Host & Microbe. 1: 23-35. PMID 18005679 DOI: 10.1016/j.chom.2006.12.001  0.48
2007 Alexander DE, Ward SL, Mizushima N, Levine B, Leib DA. Analysis of the role of autophagy in replication of herpes simplex virus in cell culture. Journal of Virology. 81: 12128-34. PMID 17855538 DOI: 10.1128/JVI.01356-07  0.48
2007 Margolis TP, Elfman FL, Leib D, Pakpour N, Apakupakul K, Imai Y, Voytek C. Spontaneous reactivation of herpes simplex virus type 1 in latently infected murine sensory ganglia. Journal of Virology. 81: 11069-74. PMID 17686862 DOI: 10.1128/JVI.00243-07  0.48
2007 Lenschow DJ, Lai C, Frias-Staheli N, Giannakopoulos NV, Lutz A, Wolff T, Osiak A, Levine B, Schmidt RE, García-Sastre A, Leib DA, Pekosz A, Knobeloch KP, Horak I, Virgin HW. IFN-stimulated gene 15 functions as a critical antiviral molecule against influenza, herpes, and Sindbis viruses. Proceedings of the National Academy of Sciences of the United States of America. 104: 1371-6. PMID 17227866 DOI: 10.1073/pnas.0607038104  0.48
2006 Pasieka TJ, Baas T, Carter VS, Proll SC, Katze MG, Leib DA. Functional genomic analysis of herpes simplex virus type 1 counteraction of the host innate response. Journal of Virology. 80: 7600-12. PMID 16840339 DOI: 10.1128/JVI.00333-06  0.48
2006 Gierasch WW, Zimmerman DL, Ward SL, Vanheyningen TK, Romine JD, Leib DA. Construction and characterization of bacterial artificial chromosomes containing HSV-1 strains 17 and KOS. Journal of Virological Methods. 135: 197-206. PMID 16647145 DOI: 10.1016/j.jviromet.2006.03.014  0.48
2006 Luker KE, Schultz T, Romine J, Leib DA, Luker GD. Transgenic reporter mouse for bioluminescence imaging of herpes simplex virus 1 infection in living mice. Virology. 347: 286-95. PMID 16430938 DOI: 10.1016/j.virol.2005.12.016  0.48
2005 Luker GD, Leib DA. Luciferase real-time bioluminescence imaging for the study of viral pathogenesis. Methods in Molecular Biology (Clifton, N.J.). 292: 285-96. PMID 15507716  0.48
2004 Strand SS, Leib DA. Role of the VP16-binding domain of vhs in viral growth, host shutoff activity, and pathogenesis. Journal of Virology. 78: 13562-72. PMID 15564467 DOI: 10.1128/JVI.78.24.13562-13572.2004  0.48
2004 Strand SS, Vanheyningen TK, Leib DA. The virion host shutoff protein of herpes simplex virus type 1 has RNA degradation activity in primary neurons. Journal of Virology. 78: 8400-3. PMID 15254212 DOI: 10.1128/JVI.78.15.8400-8403.2004  0.48
2004 Stuart PM, Summers B, Morris JE, Morrison LA, Leib DA. CD8(+) T cells control corneal disease following ocular infection with herpes simplex virus type 1. The Journal of General Virology. 85: 2055-63. PMID 15218191 DOI: 10.1099/vir.0.80049-0  0.48
2004 Krug A, Luker GD, Barchet W, Leib DA, Akira S, Colonna M. Herpes simplex virus type 1 activates murine natural interferon-producing cells through toll-like receptor 9. Blood. 103: 1433-7. PMID 14563635 DOI: 10.1182/blood-2003-08-2674  0.48
2003 Luker GD, Prior JL, Song J, Pica CM, Leib DA. Bioluminescence imaging reveals systemic dissemination of herpes simplex virus type 1 in the absence of interferon receptors. Journal of Virology. 77: 11082-93. PMID 14512556 DOI: 10.1128/JVI.77.20.11082-11093.2003  0.48
2003 Ward SL, Scheuner D, Poppers J, Kaufman RJ, Mohr I, Leib DA. In vivo replication of an ICP34.5 second-site suppressor mutant following corneal infection correlates with in vitro regulation of eIF2 alpha phosphorylation. Journal of Virology. 77: 4626-34. PMID 12663769 DOI: 10.1128/JVI.77.8.4626-4634.2003  0.48
2003 Smith TJ, Silverman RH, Leib DA. RNase L activity does not contribute to host RNA degradation induced by herpes simplex virus infection. The Journal of General Virology. 84: 925-8. PMID 12655093 DOI: 10.1099/vir.0.18695-0  0.48
2002 Luker GD, Bardill JP, Prior JL, Pica CM, Piwnica-Worms D, Leib DA. Noninvasive bioluminescence imaging of herpes simplex virus type 1 infection and therapy in living mice. Journal of Virology. 76: 12149-61. PMID 12414955 DOI: 10.1128/JVI.76.23.12149-12161.2002  0.48
2002 Keadle TL, Laycock KA, Morris JL, Leib DA, Morrison LA, Pepose JS, Stuart PM. Therapeutic vaccination with vhs(-) herpes simplex virus reduces the severity of recurrent herpetic stromal keratitis in mice. The Journal of General Virology. 83: 2361-5. PMID 12237416  0.48
2002 Leib DA. Counteraction of interferon-induced antiviral responses by herpes simplex viruses. Current Topics in Microbiology and Immunology. 269: 171-85. PMID 12224508  0.48
2002 Summers BC, Leib DA. Herpes simplex virus type 1 origins of DNA replication play no role in the regulation of flanking promoters. Journal of Virology. 76: 7020-9. PMID 12072502 DOI: 10.1128/JVI.76.14.7020-7029.2002  0.48
2002 Smith TJ, Morrison LA, Leib DA. Pathogenesis of herpes simplex virus type 2 virion host shutoff (vhs) mutants. Journal of Virology. 76: 2054-61. PMID 11836383 DOI: 10.1128/jvi.76.5.2054-2061.2002  0.48
2002 Davido DJ, Leib DA, Schaffer PA. The cyclin-dependent kinase inhibitor roscovitine inhibits the transactivating activity and alters the posttranslational modification of herpes simplex virus type 1 ICP0. Journal of Virology. 76: 1077-88. PMID 11773384  0.48
2002 Tallóczy Z, Jiang W, Virgin HW, Leib DA, Scheuner D, Kaufman RJ, Eskelinen EL, Levine B. Regulation of starvation- and virus-induced autophagy by the eIF2alpha kinase signaling pathway. Proceedings of the National Academy of Sciences of the United States of America. 99: 190-5. PMID 11756670 DOI: 10.1073/pnas.012485299  0.48
2001 Geiss BJ, Tavis JE, Metzger LM, Leib DA, Morrison LA. Temporal regulation of herpes simplex virus type 2 VP22 expression and phosphorylation. Journal of Virology. 75: 10721-9. PMID 11602713 DOI: 10.1128/JVI.75.22.10721-10729.2001  0.48
2001 Mohr I, Sternberg D, Ward S, Leib D, Mulvey M, Gluzman Y. A herpes simplex virus type 1 gamma34.5 second-site suppressor mutant that exhibits enhanced growth in cultured glioblastoma cells is severely attenuated in animals. Journal of Virology. 75: 5189-96. PMID 11333900 DOI: 10.1128/JVI.75.11.5189-5196.2001  0.48
2001 Summers BC, Margolis TP, Leib DA. Herpes simplex virus type 1 corneal infection results in periocular disease by zosteriform spread. Journal of Virology. 75: 5069-75. PMID 11333887 DOI: 10.1128/JVI.75.11.5069-5075.2001  0.48
2000 Geiss BJ, Smith TJ, Leib DA, Morrison LA. Disruption of virion host shutoff activity improves the immunogenicity and protective capacity of a replication-incompetent herpes simplex virus type 1 vaccine strain. Journal of Virology. 74: 11137-44. PMID 11070010 DOI: 10.1128/JVI.74.23.11137-11144.2000  0.48
2000 Leib DA, Machalek MA, Williams BR, Silverman RH, Virgin HW. Specific phenotypic restoration of an attenuated virus by knockout of a host resistance gene. Proceedings of the National Academy of Sciences of the United States of America. 97: 6097-101. PMID 10801979 DOI: 10.1073/pnas.100415697  0.48
2000 Smith TJ, Ackland-Berglund CE, Leib DA. Herpes simplex virus virion host shutoff (vhs) activity alters periocular disease in mice. Journal of Virology. 74: 3598-604. PMID 10729135 DOI: 10.1128/JVI.74.8.3598-3604.2000  0.48
1999 Leib DA, Harrison TE, Laslo KM, Machalek MA, Moorman NJ, Virgin HW. Interferons regulate the phenotype of wild-type and mutant herpes simplex viruses in vivo. The Journal of Experimental Medicine. 189: 663-72. PMID 9989981 DOI: 10.1084/jem.189.4.663  0.48
1998 Eide T, Marsden HS, Leib DA, Cunningham C, Davison AJ, Langeland N, Haarr L. Identification of the UL4 protein of herpes simplex virus type 1. The Journal of General Virology. 79: 3033-8. PMID 9880019  0.48
1998 Davido DJ, Leib DA. Analysis of the basal and inducible activities of the ICPO promoter of herpes simplex virus type 1. The Journal of General Virology. 79: 2093-8. PMID 9747716  0.48
1998 Jun PY, Strelow LI, Herman RC, Marsden HS, Eide T, Haarr L, Leib DA. The UL4 gene of herpes simplex virus type 1 is dispensable for latency, reactivation and pathogenesis in mice. The Journal of General Virology. 79: 1603-11. PMID 9680121  0.48
1998 Walker J, Laycock KA, Pepose JS, Leib DA. Postexposure vaccination with a virion host shutoff defective mutant reduces UV-B radiation-induced ocular herpes simplex virus shedding in mice. Vaccine. 16: 6-8. PMID 9607002 DOI: 10.1016/S0264-410X(97)00177-1  0.48
1998 Walker J, Leib DA. Protection from primary infection and establishment of latency by vaccination with a herpes simplex virus type 1 recombinant deficient in the virion host shutoff (vhs) function. Vaccine. 16: 1-5. PMID 9607001 DOI: 10.1016/S0264-410X(97)00164-3  0.48
1997 Strelow L, Smith T, Leib D. The virion host shutoff function of herpes simplex virus type 1 plays a role in corneal invasion and functions independently of the cell cycle. Virology. 231: 28-34. PMID 9143299 DOI: 10.1006/viro.1997.8497  0.48
1996 Strelow LI, Leib DA. Analysis of conserved domains of UL41 of herpes simplex virus type 1 in virion host shutoff and pathogenesis. Journal of Virology. 70: 5665-7. PMID 8764085  0.48
1996 Davido DJ, Leib DA. Role of cis-acting sequences of the ICPO promoter of herpes simplex virus type 1 in viral pathogenesis, latency and reactivation. The Journal of General Virology. 77: 1853-63. PMID 8760437  0.48
1996 Mannan RM, Leib DA, Pepose JS. Defective herpes simplex virus (amplicon) mediated gene transfer to mouse retina Investigative Ophthalmology and Visual Science. 37: S641.  0.48
1996 Davido DJ, Leib DA. Corrigendum: Role of cis-acting sequences of the ICPO promoter of herpes simplex virus type 1 in viral pathogenesis, latency and reactivation (Journal of General Virology (1996) 77 (1853-1863)) Journal of General Virology. 77: 2893.  0.48
1995 Gossen M, Bujard H, Ackland-Berglund CE, Leib DA. Efficacy of tetracycline-controlled gene expression is influenced by cell type: Commentary Biotechniques. 19: 213-217. PMID 8527141  0.48
1995 Ackland-Berglund CE, Davido DJ, Leib DA. The roles of the cAMP-response element and TATA box in expression of the herpes simplex virus type 1 latency-associated transcripts. Virology. 210: 141-51. PMID 7793066 DOI: 10.1006/viro.1995.1325  0.48
1995 Ackland-Berglund CE, Leib DA. Efficacy of tetracycline-controlled gene expression is influenced by cell type. Biotechniques. 18: 196-200. PMID 7727112  0.48
1995 Strelow LI, Leib DA. Role of the virion host shutoff (vhs) of herpes simplex virus type 1 in latency and pathogenesis. Journal of Virology. 69: 6779-86. PMID 7474089  0.48
1994 Pepose JS, Leib DA. Herpes simplex viral vectors for therapeutic gene delivery to ocular tissues. Recent breakthroughs in the molecular genetics of ocular diseases. Investigative Ophthalmology & Visual Science. 35: 2662-6. PMID 8188460  0.48
1994 Strelow LI, Laycock KA, Jun PY, Rader KA, Brady RH, Miller JK, Pepose JS, Leib DA. A structural and functional comparison of the latency-associated transcript promoters of herpes simplex virus type 1 strains KOS and McKrae. The Journal of General Virology. 75: 2475-80. PMID 8077951  0.48
1994 Kaplitt MG, Tjuvajev JG, Leib DA, Berk J, Pettigrew KD, Posner JB, Pfaff DW, Rabkin SD, Blasberg RG. Mutant herpes simplex virus induced regression of tumors growing in immunocompetent rats. Journal of Neuro-Oncology. 19: 137-47. PMID 7964989 DOI: 10.1007/BF01306455  0.48
1994 Leib DA. Experimental strategies for the prevention of herpes simplex virus reactivation International Antiviral News. 2: 39-40.  0.48
1993 Rader KA, Ackland-Berglund CE, Miller JK, Pepose JS, Leib DA. In vivo characterization of site-directed mutations in the promoter of the herpes simplex virus type 1 latency-associated transcripts. The Journal of General Virology. 74: 1859-69. PMID 8397283  0.48
1993 Leib DA, Olivo PD. Gene delivery to neurons: is herpes simplex virus the right tool for the job? Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 15: 547-54. PMID 8135768 DOI: 10.1002/bies.950150808  0.48
1991 Leib DA, Nadeau KC, Rundle SA, Schaffer PA. The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency. Proceedings of the National Academy of Sciences of the United States of America. 88: 48-52. PMID 1846042  0.48
1990 Leib DA, Ruffner KL, Hildebrand C, Schaffer PA, Wright GE, Coen DM. Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia. Antimicrobial Agents and Chemotherapy. 34: 1285-6. PMID 2168150  0.48
1989 Jacobson JG, Leib DA, Goldstein DJ, Bogard CL, Schaffer PA, Weller SK, Coen DM. A herpes simplex virus ribonucleotide reductase deletion mutant is defective for productive acute and reactivatable latent infections of mice and for replication in mouse cells. Virology. 173: 276-83. PMID 2554573 DOI: 10.1016/0042-6822(89)90244-4  0.48
1989 Coen DM, Kosz-Vnenchak M, Jacobson JG, Leib DA, Bogard CL, Schaffer PA, Tyler KL, Knipe DM. Thymidine kinase-negative herpes simplex virus mutants establish latency in mouse trigeminal ganglia but do not reactivate. Proceedings of the National Academy of Sciences of the United States of America. 86: 4736-40. PMID 2543985  0.48
1989 Leib DA, Bogard CL, Kosz-Vnenchak M, Hicks KA, Coen DM, Knipe DM, Schaffer PA. A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency. Journal of Virology. 63: 2893-900. PMID 2542601  0.48
1989 Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA. Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency. Journal of Virology. 63: 759-68. PMID 2536101  0.48
1989 Mossman SP, Leib DA, McCarthy K, Hart CA. The effects of 5-azacytidine, 12-O-tetradecanoylphorbol 13-acetate and sodium n-butyrate on reactivation of alphaherpesvirus saimiri from explant cultures of latently infected rabbit dorsal root ganglia. The Journal of General Virology. 70: 2507-12. PMID 2476529  0.48
1988 Leib DA, Hart CA, McCarthy K. Alphaherpesvirus saimiri in rabbits: a model for human encephalitis? The Journal of General Virology. 69: 1609-15. PMID 2839598  0.48
1987 Leib DA, Hart CA, McCarthy K. Characterization of four herpesviruses isolated from owl monkeys and their comparison with Herpesvirus saimiri type 1 (Herpesvirus tamarinus) and herpes simplex virus type 1. Journal of Comparative Pathology. 97: 159-69. PMID 3036914 DOI: 10.1016/0021-9975(87)90036-3  0.48
1987 Leib DA, Bradbury JM, Hart CA, McCarthy K. Genome isomerism in two alphaherpesviruses: Herpesvirus saimiri-1 (Herpesvirus tamarinus) and avian infectious laryngotracheitis virus. Brief report. Archives of Virology. 93: 287-94. PMID 3030241 DOI: 10.1007/BF01310982  0.48
1986 Leib DA, Bradbury JM, Gaskell RM, Hughes CS, Jones RC. Restriction endonuclease patterns of some European and American isolates of avian infectious laryngotracheitis virus. Avian Diseases. 30: 835-7. PMID 3028360  0.48
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