Vitezslav Bryja - Publications

Affiliations: 
2004-2007 MBB Karolinska Institute, Stockholm, Sweden 

100 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Colozza G, Lee H, Merenda A, Wu SS, Català-Bordes A, Radaszkiewicz TW, Jordens I, Lee JH, Bamford AD, Farnhammer F, Low TY, Maurice MM, Bryja V, Kim J, Koo BK. Intestinal Paneth cell differentiation relies on asymmetric regulation of Wnt signaling by Daam1/2. Science Advances. 9: eadh9673. PMID 38000028 DOI: 10.1126/sciadv.adh9673  0.445
2022 Hankeova S, Van Hul N, Laznovsky J, Verboven E, Mangold K, Hensens N, Adori C, Verhoef E, Zikmund T, Dawit F, Kavkova M, Salplachta J, Sjöqvist M, Johansson BR, Hassan MG, ... ... Bryja V, et al. Sex differences and risk factors for bleeding in Alagille syndrome. Embo Molecular Medicine. e15809. PMID 36345711 DOI: 10.15252/emmm.202215809  0.559
2022 Dave Z, Vondálová Blanářová O, Čada Š, Janovská P, Zezula N, Běhal M, Hanáková K, Ganji SR, Krejci P, Gömöryová K, Peschelová H, Šmída M, Zdráhal Z, Pavlová Š, Kotašková J, ... ... Bryja V, et al. Lyn Phosphorylates and Controls ROR1 Surface Dynamics During Chemotaxis of CLL Cells. Frontiers in Cell and Developmental Biology. 10: 838871. PMID 35295854 DOI: 10.3389/fcell.2022.838871  0.324
2022 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Bryja V, et al. Correction: MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 149. PMID 35119069 DOI: 10.1242/dev.200517  0.769
2021 Čada Š, Bryja V. Local Wnt signalling in the asymmetric migrating vertebrate cells. Seminars in Cell & Developmental Biology. PMID 34896020 DOI: 10.1016/j.semcdb.2021.11.020  0.396
2021 Radaszkiewicz T, Nosková M, Gömöryová K, Vondálová Blanářová O, Radaszkiewicz KA, Picková M, Víchová R, Gybeľ T, Kaiser K, Demková L, Kučerová L, Bárta T, Potěšil D, Zdráhal Z, Souček K, ... Bryja V, et al. RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy. Elife. 10. PMID 34702444 DOI: 10.7554/eLife.65759  0.362
2021 Micka M, Bryja V. Can We Pharmacologically Target Dishevelled: The Key Signal Transducer in the Wnt Pathways? Handbook of Experimental Pharmacology. PMID 34382124 DOI: 10.1007/164_2021_527  0.362
2021 Paclíková P, Radaszkiewicz TW, Potěšil D, Harnoš J, Zdráhal Z, Bryja V. Roles of individual human Dishevelled paralogs in the Wnt signalling pathways. Cellular Signalling. 85: 110058. PMID 34082011 DOI: 10.1016/j.cellsig.2021.110058  0.405
2021 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, ... ... Bryja V, et al. MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development (Cambridge, England). 148. PMID 34032267 DOI: 10.1242/dev.192054  0.79
2021 Suthon S, Perkins RS, Bryja V, Miranda-Carboni GA, Krum SA. WNT5B in Physiology and Disease. Frontiers in Cell and Developmental Biology. 9: 667581. PMID 34017835 DOI: 10.3389/fcell.2021.667581  0.353
2021 Bernatik O, Paclikova P, Kotrbova A, Bryja V, Cajanek L. Primary Cilia Formation Does Not Rely on WNT/β-Catenin Signaling. Frontiers in Cell and Developmental Biology. 9: 623753. PMID 33718363 DOI: 10.3389/fcell.2021.623753  0.764
2021 Hankeova S, Salplachta J, Zikmund T, Kavkova M, Van Hul N, Brinek A, Smekalova V, Laznovsky J, Dawit F, Jaros J, Bryja V, Lendahl U, Ellis E, Nemeth A, Fischler B, et al. DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome. Elife. 10. PMID 33635272 DOI: 10.7554/eLife.60916  0.569
2020 Bosakova M, Abraham SP, Nita A, Hruba E, Buchtova M, Taylor SP, Duran I, Martin J, Svozilova K, Barta T, Varecha M, Balek L, Kohoutek J, Radaszkiewicz T, Pusapati GV, ... Bryja V, et al. Mutations in GRK2 cause Jeune syndrome by impairing Hedgehog and canonical Wnt signaling. Embo Molecular Medicine. 12: e11739. PMID 33200460 DOI: 10.15252/emmm.201911739  0.307
2020 Spit M, Fenderico N, Jordens I, Radaszkiewicz T, Lindeboom RG, Bugter JM, Cristobal A, Ootes L, van Osch M, Janssen E, Boonekamp KE, Hanakova K, Potesil D, Zdrahal Z, Boj SF, ... ... Bryja V, et al. RNF43 truncations trap CK1 to drive niche-independent self-renewal in cancer. The Embo Journal. 39: e103932. PMID 32965059 DOI: 10.15252/Embj.2019103932  0.425
2020 Kaiser K, Bryja V. Choroid Plexus: The Orchestrator of Long-Range Signalling Within the CNS. International Journal of Molecular Sciences. 21. PMID 32635478 DOI: 10.3390/Ijms21134760  0.388
2020 Radaszkiewicz T, Bryja V. Protease associated domain of RNF43 is not necessary for the suppression of Wnt/β-catenin signaling in human cells. Cell Communication and Signaling : Ccs. 18: 91. PMID 32527265 DOI: 10.1186/s12964-020-00559-0  0.327
2020 Bernatik O, Paclikova P, Sri Ganji R, Bryja V. Activity of Smurf2 Ubiquitin Ligase Is Regulated by the Wnt Pathway Protein Dishevelled. Cells. 9. PMID 32392721 DOI: 10.3390/Cells9051147  0.515
2020 Kratzer MC, Becker SFS, Grund A, Merks A, Harnoš J, Bryja V, Giehl K, Kashef J, Borchers A. The Rho guanine nucleotide exchange factor Trio is required for neural crest cell migration and interacts with Dishevelled. Development (Cambridge, England). 147. PMID 32366678 DOI: 10.1242/dev.186338  0.318
2020 Kozlova V, Ledererova A, Ladungova A, Peschelova H, Janovska P, Slusarczyk A, Domagala J, Kopcil P, Vakulova V, Oppelt J, Bryja V, Doubek M, Mayer J, Pospisilova S, Smida M. CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells. Plos One. 15: e0229170. PMID 32210425 DOI: 10.1371/Journal.Pone.0229170  0.344
2020 Kotrbová A, Ovesná P, Gybel' T, Radaszkiewicz T, Bednaříková M, Hausnerová J, Jandáková E, Minář L, Crha I, Weinberger V, Záveský L, Bryja V, Pospíchalová V. WNT signaling inducing activity in ascites predicts poor outcome in ovarian cancer. Theranostics. 10: 537-552. PMID 31903136 DOI: 10.7150/thno.37423  0.394
2019 Hanáková K, Bernatík O, Kravec M, Micka M, Kumar J, Harnoš J, Ovesná P, Paclíková P, Rádsetoulal M, Potěšil D, Tripsianes K, Čajánek L, Zdráhal Z, Bryja V. Comparative phosphorylation map of Dishevelled 3 links phospho-signatures to biological outputs. Cell Communication and Signaling : Ccs. 17: 170. PMID 31870452 DOI: 10.1186/S12964-019-0470-Z  0.719
2019 Kaiser K, Gyllborg D, Procházka J, Salašová A, Kompaníková P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnoš J, Procházková M, Potěšil D, Barker RA, Casado ÁG, Zdráhal Z, Sedláček R, ... ... Bryja V, et al. WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nature Communications. 10: 1498. PMID 30940800 DOI: 10.1038/S41467-019-09298-4  0.77
2018 Mentink RA, Rella L, Radaszkiewicz TW, Gybel T, Betist MC, Bryja V, Korswagen HC. The planar cell polarity protein VANG-1/Vangl negatively regulates Wnt/β-catenin signaling through a Dvl dependent mechanism. Plos Genetics. 14: e1007840. PMID 30532125 DOI: 10.1371/journal.pgen.1007840  0.415
2018 Strakova K, Kowalski-Jahn M, Gybel T, Valnohova J, Dhople VM, Harnoš J, Bernatik O, Sri Ganji R, Zdrahal Z, Mulder J, Lindskog C, Bryja V, Schulte G. Dishevelled enables casein kinase 1-mediated phosphorylation of Frizzled 6 required for cell membrane localization. The Journal of Biological Chemistry. PMID 30309985 DOI: 10.1074/Jbc.Ra118.004656  0.669
2018 Lee Y, Kim NH, Cho ES, Yang JH, Cha YH, Kang HE, Yun JS, Cho SB, Lee SH, Paclikova P, Radaszkiewicz TW, Bryja V, Kang CG, Yuk YS, Cha SY, et al. Dishevelled has a YAP nuclear export function in a tumor suppressor context-dependent manner. Nature Communications. 9: 2301. PMID 29895829 DOI: 10.1038/S41467-018-04757-W  0.419
2018 Fatima I, El-Ayachi I, Taotao L, Angeles Lillo M, Krutilina RI, Seagroves TN, Radaszkiewicz TW, Hutnan M, Bryja V, Krum SA, Rivas F, Miranda-Carboni GA. Correction: The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer. Plos One. 13: e0197796. PMID 29771986 DOI: 10.1371/Journal.Pone.0197796  0.331
2018 Janovska P, Verner J, Kohoutek J, Bryjova L, Gregorova M, Dzimkova M, Skabrahova H, Radaszkiewicz T, Ovesna P, Vondalova Blanarova O, Nemcova T, Hoferova Z, Vasickova K, Smyckova L, Egle A, ... ... Bryja V, et al. Casein Kinase 1 is a Therapeutic Target in Chronic Lymphocytic Leukemia. Blood. PMID 29317454 DOI: 10.1182/Blood-2017-05-786947  0.383
2018 Hankeova S, Zikmund T, Kavkova M, Brinek A, Lendahl U, Kaiser J, Bryja V, Andersson E. Double resin casting micro computed tomography (DUCT) of biliary and vascular system Journal of Hepatology. 68: S414-S415. DOI: 10.1016/s0168-8278(18)31068-7  0.529
2017 Fatima I, El-Ayachi I, Taotao L, Lillo MA, Krutilina R, Seagroves TN, Radaszkiewicz TW, Hutnan M, Bryja V, Krum SA, Rivas F, Miranda-Carboni GA. The natural compound Jatrophone interferes with Wnt/β-catenin signaling and inhibits proliferation and EMT in human triple-negative breast cancer. Plos One. 12: e0189864. PMID 29281678 DOI: 10.1371/Journal.Pone.0189864  0.387
2017 Schulte G, Bryja V. WNT signalling: mechanisms and therapeutic opportunities. British Journal of Pharmacology. 174: 4543-4546. PMID 29235106 DOI: 10.1111/Bph.14065  0.667
2017 Andersson ER, Chivukula IV, Hankeova S, Sjöqvist M, Tsoi YL, Ramsköld D, Masek J, Elmansuri A, Hoogendoorn A, Vazquez E, Storvall H, Netušilová J, Huch M, Fischler B, Ellis E, ... ... Bryja V, et al. Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations. Gastroenterology. PMID 29162437 DOI: 10.1053/J.Gastro.2017.11.002  0.6
2017 Bryja V, Červenka I, Čajánek L. The connections of Wnt pathway components with cell cycle and centrosome: side effects or a hidden logic? Critical Reviews in Biochemistry and Molecular Biology. 1-24. PMID 28741966 DOI: 10.1080/10409238.2017.1350135  0.773
2017 Janovská P, Bryja V. Wnt signalling pathways in chronic lymphocytic leukaemia and B-cell lymphomas. British Journal of Pharmacology. PMID 28703283 DOI: 10.1111/bph.13949  0.35
2017 Salašová A, Yokota C, Potěšil D, Zdráhal Z, Bryja V, Arenas E. A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway. Molecular Neurodegeneration. 12: 54. PMID 28697798 DOI: 10.1186/S13024-017-0193-9  0.625
2017 Paclíková P, Bernatík O, Radaszkiewicz TW, Bryja V. N-terminal part of Dishevelled DEP domain is required for Wnt/β-catenin signaling in mammalian cells. Molecular and Cellular Biology. PMID 28674183 DOI: 10.1128/MCB.00145-17  0.329
2017 Strakova K, Matricon P, Yokota C, Arthofer E, Bernatik O, Rodriguez D, Arenas E, Carlsson J, Bryja V, Schulte G. The tyrosine Y250(2.39) in Frizzled 4 defines a conserved motif important for structural integrity of the receptor and recruitment of Disheveled. Cellular Signalling. PMID 28668722 DOI: 10.1016/J.Cellsig.2017.06.018  0.733
2017 Bernatik O, Radaszkiewicz T, Behal M, Dave Z, Witte F, Mahl A, Cernohorsky NH, Krejci P, Stricker S, Bryja V. A Novel Role for the BMP Antagonist Noggin in Sensitizing Cells to Non-canonical Wnt-5a/Ror2/Disheveled Pathway Activation. Frontiers in Cell and Developmental Biology. 5: 47. PMID 28523267 DOI: 10.3389/Fcell.2017.00047  0.509
2017 Putnová I, Dosedělová H, Bryja V, Landová M, Buchtová M, Štembírek J. Angled Growth of the Dental Lamina Is Accompanied by Asymmetrical Expression of the WNT Pathway Receptor Frizzled 6. Frontiers in Physiology. 8: 29. PMID 28197104 DOI: 10.3389/Fphys.2017.00029  0.433
2016 Poppova L, Janovska P, Plevova K, Radova L, Plesingerova H, Borsky M, Kotaskova J, Kantorova B, Hlozkova M, Figulova J, Brychtova Y, Machalova M, Urik M, Doubek M, Kozubik A, ... ... Bryja V, et al. Decreased WNT3 expression in chronic lymphocytic leukaemia is a hallmark of disease progression and identifies patients with worse prognosis in the subgroup with mutated IGHV. British Journal of Haematology. 175: 851-859. PMID 27651098 DOI: 10.1111/Bjh.14312  0.426
2016 Zemanova J, Hylse O, Collakova J, Vesely P, Oltova A, Borsky M, Zaprazna K, Kasparkova M, Janovska P, Verner J, Kohoutek J, Dzimkova M, Bryja V, Jaskova Z, Brychtova Y, et al. Chk1 inhibition significantly potentiates activity of nucleoside analogs in TP53-mutated B-lymphoid cells. Oncotarget. PMID 27556692 DOI: 10.18632/Oncotarget.11388  0.332
2016 Linke F, Harenberg M, Nietert MM, Zaunig S, von Bonin F, Arlt A, Szczepanowski M, Weich HA, Lutz S, Dullin C, Janovská P, Krafčíková M, Trantírek L, Ovesná P, Klapper W, ... ... Bryja V, et al. Microenvironmental interactions between endothelial and lymphoma cells-a role for the canonical WNT pathway in Hodgkin lymphoma. Leukemia. PMID 27535218 DOI: 10.1038/Leu.2016.232  0.303
2016 Cervenka I, Valnohova J, Bernatik O, Harnos J, Radsetoulal M, Sedova K, Hanakova K, Potesil D, Sedlackova M, Salasova A, Steinhart Z, Angers S, Schulte G, Hampl A, Zdrahal Z, ... Bryja V, et al. Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 27486244 DOI: 10.1073/Pnas.1608783113  0.663
2016 Linke F, Zaunig S, Nietert MM, von Bonin F, Lutz S, Dullin C, Janovská P, Beissbarth T, Alves F, Klapper W, Bryja V, Pukrop T, Trümper L, Wilting J, Kube D. WNT5A: a motility-promoting factor in Hodgkin lymphoma. Oncogene. PMID 27270428 DOI: 10.1038/onc.2016.183  0.319
2016 Janovska P, Poppova L, Plevova K, Plesingerova H, Behal M, Kaucka M, Ovesna P, Hlozkova M, Borsky M, Stehlikova O, Brychtova Y, Doubek M, Machalova M, Baskar S, Kozubik A, ... ... Bryja V, et al. Autocrine Signaling by Wnt-5a Deregulates Chemotaxis of Leukemic Cells and Predicts Clinical Outcome in Chronic Lymphocytic Leukemia. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 459-69. PMID 26240275 DOI: 10.1158/1078-0432.Ccr-15-0154  0.431
2015 Kaucká M, Petersen J, Janovská P, Radaszkiewicz T, Smy?ková L, Daulat AM, Borg JP, Schulte G, Bryja V. Asymmetry of VANGL2 in migrating lymphocytes as a tool to monitor activity of the mammalian WNT/planar cell polarity pathway. Cell Communication and Signaling : Ccs. 13: 2. PMID 25627785 DOI: 10.1186/S12964-014-0079-1  0.654
2015 Buchtova M, Oralova V, Aklian A, Masek J, Vesela I, Ouyang Z, Obadalova T, Konecna Z, Spoustova T, Pospisilova T, Matula P, Varecha M, Balek L, Gudernova I, Jelinkova I, ... ... Bryja V, et al. Fibroblast growth factor and canonical WNT/β-catenin signaling cooperate in suppression of chondrocyte differentiation in experimental models of FGFR signaling in cartilage. Biochimica Et Biophysica Acta. 1852: 839-50. PMID 25558817 DOI: 10.1016/J.Bbadis.2014.12.020  0.477
2014 Bernatík O, Šedová K, Schille C, Ganji RS, ?ervenka I, Trantírek L, Schambony A, Zdráhal Z, Bryja V. Functional analysis of dishevelled-3 phosphorylation identifies distinct mechanisms driven by casein kinase 1ϵ and frizzled5. The Journal of Biological Chemistry. 289: 23520-33. PMID 24993822 DOI: 10.1074/Jbc.M114.590638  0.303
2014 De Groot REA, Ganji RS, Bernatik O, Lloyd-Lewis B, Seipel K, Šedová K, Zdráhal Z, Dhople VM, Dale TC, Korswagen HC, Bryja V. Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway Science Signaling. 7. PMID 24643799 DOI: 10.1126/Scisignal.2004985  0.508
2014 Kilander MB, Petersen J, Andressen KW, Ganji RS, Levy FO, Schuster J, Dahl N, Bryja V, Schulte G. Disheveled regulates precoupling of heterotrimeric G proteins to Frizzled 6. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 2293-305. PMID 24500924 DOI: 10.1096/Fj.13-246363  0.632
2014 Seitz K, Dürsch V, Harnoš J, Bryja V, Gentzel M, Schambony A. β-Arrestin interacts with the beta/gamma subunits of trimeric G-proteins and dishevelled in the Wnt/Ca(2+) pathway in xenopus gastrulation. Plos One. 9: e87132. PMID 24489854 DOI: 10.1371/Journal.Pone.0087132  0.437
2014 Kríz V, Pospíchalová V, Masek J, Kilander MB, Slavík J, Tanneberger K, Schulte G, Machala M, Kozubík A, Behrens J, Bryja V. β-arrestin promotes Wnt-induced low density lipoprotein receptor-related protein 6 (Lrp6) phosphorylation via increased membrane recruitment of Amer1 protein. The Journal of Biological Chemistry. 289: 1128-41. PMID 24265322 DOI: 10.1074/Jbc.M113.498444  0.662
2013 Soldano A, Okray Z, Janovska P, Tmejová K, Reynaud E, Claeys A, Yan J, Atak ZK, De Strooper B, Dura JM, Bryja V, Hassan BA. The Drosophila homologue of the amyloid precursor protein is a conserved modulator of Wnt PCP signaling. Plos Biology. 11: e1001562. PMID 23690751 DOI: 10.1371/journal.pbio.1001562  0.33
2013 Kaucká M, Plevová K, Pavlová S, Janovská P, Mishra A, Verner J, Procházková J, Krejcí P, Kotasková J, Ovesná P, Tichy B, Brychtová Y, Doubek M, Kozubík A, Mayer J, ... ... Bryja V, et al. The planar cell polarity pathway drives pathogenesis of chronic lymphocytic leukemia by the regulation of B-lymphocyte migration. Cancer Research. 73: 1491-501. PMID 23338609 DOI: 10.1158/0008-5472.Can-12-1752  0.412
2013 Andersson ER, Saltó C, Villaescusa JC, Cajanek L, Yang S, Bryjova L, Nagy II, Vainio SJ, Ramirez C, Bryja V, Arenas E. Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells. Proceedings of the National Academy of Sciences of the United States of America. 110: E602-10. PMID 23324743 DOI: 10.1073/Pnas.1208524110  0.798
2013 ÄŒajánek L, Ganji RS, Henriques-Oliveira C, Theofilopoulos S, Koník P, Bryja V, Arenas E. Tiam1 regulates the Wnt/Dvl/Rac1 signaling pathway and the differentiation of midbrain dopaminergic neurons. Molecular and Cellular Biology. 33: 59-70. PMID 23109420 DOI: 10.1128/Mcb.00745-12  0.832
2012 Krejci P, Aklian A, Kaucka M, Sevcikova E, Prochazkova J, Masek JK, Mikolka P, Pospisilova T, Spoustova T, Weis M, Paznekas WA, Wolf JH, Gutkind JS, Wilcox WR, Kozubik A, ... ... Bryja V, et al. Receptor tyrosine kinases activate canonical WNT/β-catenin signaling via MAP kinase/LRP6 pathway and direct β-catenin phosphorylation. Plos One. 7: e35826. PMID 22558232 DOI: 10.1371/Journal.Pone.0035826  0.424
2012 Kele J, Andersson ER, Villaescusa JC, Cajanek L, Parish CL, Bonilla S, Toledo EM, Bryja V, Rubin JS, Shimono A, Arenas E. SFRP1 and SFRP2 dose-dependently regulate midbrain dopamine neuron development in vivo and in embryonic stem cells. Stem Cells (Dayton, Ohio). 30: 865-75. PMID 22290867 DOI: 10.1002/Stem.1049  0.797
2011 Procházková J, Kabátková M, Bryja V, Umannová L, Bernatík O, Kozubík A, Machala M, Vondrácek J. The interplay of the aryl hydrocarbon receptor and β-catenin alters both AhR-dependent transcription and Wnt/β-catenin signaling in liver progenitors. Toxicological Sciences : An Official Journal of the Society of Toxicology. 122: 349-60. PMID 21602191 DOI: 10.1093/toxsci/kfr129  0.33
2011 Tanneberger K, Pfister AS, Kriz V, Bryja V, Schambony A, Behrens J. Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1). The Journal of Biological Chemistry. 286: 19204-14. PMID 21498506 DOI: 10.1074/Jbc.M111.224881  0.378
2011 Tanneberger K, Pfister AS, Brauburger K, Schneikert J, Hadjihannas MV, Kriz V, Schulte G, Bryja V, Behrens J. Amer1/WTX couples Wnt-induced formation of PtdIns(4,5)P2 to LRP6 phosphorylation. The Embo Journal. 30: 1433-43. PMID 21304492 DOI: 10.1038/Emboj.2011.28  0.659
2011 Bernatik O, Ganji RS, Dijksterhuis JP, Konik P, Cervenka I, Polonio T, Krejci P, Schulte G, Bryja V. Sequential activation and inactivation of Dishevelled in the Wnt/beta-catenin pathway by casein kinases. The Journal of Biological Chemistry. 286: 10396-410. PMID 21285348 DOI: 10.1074/jbc.M110.169870  0.677
2011 Kilander MB, Dijksterhuis JP, Ganji RS, Bryja V, Schulte G. WNT-5A stimulates the GDP/GTP exchange at pertussis toxin-sensitive heterotrimeric G proteins. Cellular Signalling. 23: 550-4. PMID 21070854 DOI: 10.1016/J.Cellsig.2010.11.004  0.633
2011 Červenka I, Wolf J, Mašek J, Krejci P, Wilcox WR, Kozubík A, Schulte G, Gutkind JS, Bryja V. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Molecular and Cellular Biology. 31: 179-89. PMID 20974802 DOI: 10.1128/Mcb.00550-10  0.655
2011 Schulte G, Bryja V, Schambony A. 19thActa Physiologicainternational symposium ‘WNT Signaling in Physiology and Disease’- a long way from developmental biology to physiology Acta Physiologica. 204: 6-7. DOI: 10.1111/J.1748-1716.2011.02326.X  0.659
2011 Kaucka M, Verner J, Prochazkova J, Plevova K, Stehlikova O, Krejcil P, Kozubik A, Mayer J, Pospisilova S, Bryja V. 1.26 Wnt/PCP Pathway Regulates B-Cell Migration in Chronic Lymphocytic Leukemia Clinical Lymphoma Myeloma and Leukemia. 11: S157-S158. DOI: 10.1016/J.Clml.2011.09.027  0.381
2010 Cajanek L, Adlerz L, Bryja V, Arenas E. WNT unrelated activities in commercially available preparations of recombinant WNT3a. Journal of Cellular Biochemistry. 111: 1077-9. PMID 20665540 DOI: 10.1002/Jcb.22771  0.818
2010 Krejci P, Murakami S, Prochazkova J, Trantirek L, Chlebova K, Ouyang Z, Aklian A, Smutny J, Bryja V, Kozubik A, Wilcox WR. NF449 is a novel inhibitor of fibroblast growth factor receptor 3 (FGFR3) signaling active in chondrocytes and multiple myeloma cells. The Journal of Biological Chemistry. 285: 20644-53. PMID 20439987 DOI: 10.1074/Jbc.M109.083626  0.395
2010 Krejci P, Prochazkova J, Smutny J, Chlebova K, Lin P, Aklian A, Bryja V, Kozubik A, Wilcox WR. FGFR3 signaling induces a reversible senescence phenotype in chondrocytes similar to oncogene-induced premature senescence. Bone. 47: 102-10. PMID 20362703 DOI: 10.1016/J.Ydbio.2010.05.341  0.444
2010 Witte F, Bernatik O, Kirchner K, Masek J, Mahl A, Krejci P, Mundlos S, Schambony A, Bryja V, Stricker S. Negative regulation of Wnt signaling mediated by CK1-phosphorylated Dishevelled via Ror2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2417-26. PMID 20215527 DOI: 10.1096/Fj.09-150615  0.497
2010 Lindqvist M, Horn Z, Bryja V, Schulte G, Papachristou P, Ajima R, Dyberg C, Arenas E, Yamaguchi TP, Lagercrantz H, Ringstedt T. Vang-like protein 2 and Rac1 interact to regulate adherens junctions. Journal of Cell Science. 123: 472-83. PMID 20067994 DOI: 10.1242/Jcs.048074  0.759
2010 Sousa KM, Villaescusa JC, Cajanek L, Ondr JK, Castelo-Branco G, Hofstra W, Bryja V, Palmberg C, Bergman T, Wainwright B, Lang RA, Arenas E. Wnt2 regulates progenitor proliferation in the developing ventral midbrain. The Journal of Biological Chemistry. 285: 7246-53. PMID 20018874 DOI: 10.1074/Jbc.M109.079822  0.821
2010 Schulte G, Schambony A, Bryja V. beta-Arrestins - scaffolds and signalling elements essential for WNT/Frizzled signalling pathways? British Journal of Pharmacology. 159: 1051-8. PMID 19888962 DOI: 10.1111/J.1476-5381.2009.00466.X  0.682
2010 Andersson ER, Bryjova L, Biris K, Yamaguchi TP, Arenas E, Bryja V. Genetic interaction between Lrp6 and Wnt5a during mouse development. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 237-45. PMID 19795512 DOI: 10.1002/Dvdy.22101  0.767
2009 Cajánek L, Ribeiro D, Liste I, Parish CL, Bryja V, Arenas E. Wnt/beta-catenin signaling blockade promotes neuronal induction and dopaminergic differentiation in embryonic stem cells. Stem Cells (Dayton, Ohio). 27: 2917-27. PMID 19725118 DOI: 10.1002/Stem.210  0.831
2009 Kunke D, Bryja V, Mygland L, Arenas E, Krauss S. Inhibition of canonical Wnt signaling promotes gliogenesis in P0-NSCs. Biochemical and Biophysical Research Communications. 386: 628-33. PMID 19545542 DOI: 10.1016/J.Bbrc.2009.06.084  0.662
2009 Yang DH, Yoon JY, Lee SH, Bryja V, Andersson ER, Arenas E, Kwon YG, Choi KY. Wnt5a is required for endothelial differentiation of embryonic stem cells and vascularization via pathways involving both Wnt/beta-catenin and protein kinase Calpha. Circulation Research. 104: 372-9. PMID 19096028 DOI: 10.1161/Circresaha.108.185405  0.775
2009 Bryja V, Andersson ER, Schambony A, Esner M, Bryjová L, Biris KK, Hall AC, Kraft B, Cajanek L, Yamaguchi TP, Buckingham M, Arenas E. The extracellular domain of Lrp5/6 inhibits noncanonical Wnt signaling in vivo. Molecular Biology of the Cell. 20: 924-36. PMID 19056682 DOI: 10.1091/Mbc.E08-07-0711  0.814
2009 Andersson T, Södersten E, Duckworth JK, Cascante A, Fritz N, Sacchetti P, Cervenka I, Bryja V, Hermanson O. CXXC5 is a novel BMP4-regulated modulator of Wnt signaling in neural stem cells. The Journal of Biological Chemistry. 284: 3672-81. PMID 19001364 DOI: 10.1074/Jbc.M808119200  0.772
2009 Krejci P, Prochazkova J, Bryja V, Jelinkova P, Pejchalova K, Kozubik A, Thompson LM, Wilcox WR. Fibroblast growth factor inhibits interferon gamma-STAT1 and interleukin 6-STAT3 signaling in chondrocytes. Cellular Signalling. 21: 151-60. PMID 18950705 DOI: 10.1016/J.Cellsig.2008.10.006  0.37
2009 Prochazkova J, Bryja V, Richterova M, Bernatik O, Kozubik A, Machala M, Vondracek J. The crosstalk between Ah receptor and canonical Wnt signaling extends beyond a simple regulation of AhR expression Toxicology Letters. 189: S96-S97. DOI: 10.1016/J.Toxlet.2009.06.316  0.422
2008 Krejci P, Salazar L, Kashiwada TA, Chlebova K, Salasova A, Thompson LM, Bryja V, Kozubik A, Wilcox WR. Analysis of STAT1 activation by six FGFR3 mutants associated with skeletal dysplasia undermines dominant role of STAT1 in FGFR3 signaling in cartilage. Plos One. 3: e3961. PMID 19088846 DOI: 10.1371/Journal.Pone.0003961  0.413
2008 Jung GA, Yoon JY, Moon BS, Yang DH, Kim HY, Lee SH, Bryja V, Arenas E, Choi KY. Valproic acid induces differentiation and inhibition of proliferation in neural progenitor cells via the beta-catenin-Ras-ERK-p21Cip/WAF1 pathway. Bmc Cell Biology. 9: 66. PMID 19068119 DOI: 10.1186/1471-2121-9-66  0.665
2008 Bryja V, Pacherník J, Vondráček J, Souček K, Čajánek L, Horvath V, Holubcová Z, Dvořák P, Hampl A. Lineage specific composition of cyclin D-CDK4/CDK6-p27 complexes reveals distinct functions of CDK4, CDK6 and individual D-type cyclins in differentiating cells of embryonic origin. Cell Proliferation. 41: 875-893. PMID 19040567 DOI: 10.1111/J.1365-2184.2008.00556.X  0.724
2008 Andersson ER, Prakash N, Cajanek L, Minina E, Bryja V, Bryjova L, Yamaguchi TP, Hall AC, Wurst W, Arenas E. Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. Plos One. 3: e3517. PMID 18953410 DOI: 10.1371/Journal.Pone.0003517  0.821
2008 Bryja V, Schambony A, Cajánek L, Dominguez I, Arenas E, Schulte G. Beta-arrestin and casein kinase 1/2 define distinct branches of non-canonical WNT signalling pathways. Embo Reports. 9: 1244-50. PMID 18953287 DOI: 10.1038/Embor.2008.193  0.814
2008 Andäng M, Hjerling-Leffler J, Moliner A, Lundgren TK, Castelo-Branco G, Nanou E, Pozas E, Bryja V, Halliez S, Nishimaru H, Wilbertz J, Arenas E, Koltzenburg M, Charnay P, El Manira A, et al. Histone H2AX-dependent GABA(A) receptor regulation of stem cell proliferation. Nature. 451: 460-4. PMID 18185516 DOI: 10.1038/Nature06488  0.772
2007 Schulte G, Bryja V. The Frizzled family of unconventional G-protein-coupled receptors. Trends in Pharmacological Sciences. 28: 518-25. PMID 17884187 DOI: 10.1016/J.Tips.2007.09.001  0.628
2007 Bryja V, Cajánek L, Grahn A, Schulte G. Inhibition of endocytosis blocks Wnt signalling to beta-catenin by promoting dishevelled degradation. Acta Physiologica (Oxford, England). 190: 55-61. PMID 17428233 DOI: 10.1111/J.1365-201X.2007.01688.X  0.815
2007 Bryja V, Gradl D, Schambony A, Arenas E, Schulte G. Beta-arrestin is a necessary component of Wnt/beta-catenin signaling in vitro and in vivo. Proceedings of the National Academy of Sciences of the United States of America. 104: 6690-5. PMID 17426148 DOI: 10.1073/Pnas.0611356104  0.724
2007 Bryja V, Schulte G, Rawal N, Grahn A, Arenas E. Wnt-5a induces Dishevelled phosphorylation and dopaminergic differentiation via a CK1-dependent mechanism. Journal of Cell Science. 120: 586-95. PMID 17244647 DOI: 10.1242/Jcs.03368  0.808
2007 Bryja V, Schulte G, Arenas E. Wnt-3a utilizes a novel low dose and rapid pathway that does not require casein kinase 1-mediated phosphorylation of Dvl to activate beta-catenin. Cellular Signalling. 19: 610-6. PMID 17027228 DOI: 10.1016/J.Cellsig.2006.08.011  0.73
2006 Bryja V, Bonilla S, Arenas E. Derivation of mouse embryonic stem cells. Nature Protocols. 1: 2082-7. PMID 17487198 DOI: 10.1038/Nprot.2006.355  0.499
2006 Bryja V, Bonilla S, Cajánek L, Parish CL, Schwartz CM, Luo Y, Rao MS, Arenas E. An efficient method for the derivation of mouse embryonic stem cells. Stem Cells (Dayton, Ohio). 24: 844-9. PMID 16339993 DOI: 10.1634/Stemcells.2005-0444  0.785
2006 Castelo-Branco G, Sousa KM, Bryja V, Pinto L, Wagner J, Arenas E. Ventral midbrain glia express region-specific transcription factors and regulate dopaminergic neurogenesis through Wnt-5a secretion. Molecular and Cellular Neurosciences. 31: 251-62. PMID 16243537 DOI: 10.1016/J.Mcn.2005.09.014  0.817
2005 Bryja V, Cajánek L, Pacherník J, Hall AC, Horváth V, Dvorák P, Hampl A. Abnormal development of mouse embryoid bodies lacking p27Kip1 cell cycle regulator. Stem Cells (Dayton, Ohio). 23: 965-74. PMID 15941856 DOI: 10.1634/Stemcells.2004-0174  0.801
2005 Schulte G, Bryja V, Rawal N, Castelo-Branco G, Sousa KM, Arenas E. Purified Wnt-5a increases differentiation of midbrain dopaminergic cells and dishevelled phosphorylation. Journal of Neurochemistry. 92: 1550-3. PMID 15748172 DOI: 10.1111/J.1471-4159.2004.03022.X  0.795
2004 Krejci P, Bryja V, Pachernik J, Hampl A, Pogue R, Mekikian P, Wilcox WR. FGF2 inhibits proliferation and alters the cartilage-like phenotype of RCS cells. Experimental Cell Research. 297: 152-64. PMID 15194433 DOI: 10.1016/J.Yexcr.2004.03.011  0.377
2003 Bryja V, Pachernik J, Kubala L, Hampl A, Dvorak P. The reverse tetracycline-controlled transactivator rtTA2s-S2 is toxic in mouse embryonic stem cells. Reproduction, Nutrition, Development. 43: 477-86. PMID 15141433 DOI: 10.1051/Rnd:2004001  0.387
2003 Anger M, Bryja V, Jirmanova L, Hampl A, Carrington M, Motlik J, Dvorak P, Kubelka M. The appearance of truncated cyclin A2 correlates with differentiation of mouse embryonic stem cells. Biochemical and Biophysical Research Communications. 302: 825-30. PMID 12646244 DOI: 10.1016/S0006-291X(03)00270-5  0.399
2001 Sutovsky P, Motlik J, Neuber E, Pavlok A, Schatten G, Palecek J, Hyttel P, Adebayo OT, Adwan K, Alberio R, Bagis H, Bataineh Z, Bjerregaard B, Bodo S, Bryja V, et al. Accumulation of the proteolytic marker peptide ubiquitin in the trophoblast of mammalian blastocysts Cloning and Stem Cells. 3: 157-161. PMID 11945225 DOI: 10.1089/153623001753205115  0.337
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