Wolfgang Wurst - Publications

Affiliations: 
Helmholtz Zentrum München 

112 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Nouri P, Götz S, Rauser B, Irmler M, Peng C, Trümbach D, Kempny C, Lechermeier CG, Bryniok A, Dlugos A, Euchner E, Beckers J, Brodski C, Klümper C, Wurst W, et al. Dose-Dependent and Subset-Specific Regulation of Midbrain Dopaminergic Neuron Differentiation by LEF1-Mediated WNT1/b-Catenin Signaling. Frontiers in Cell and Developmental Biology. 8: 587778. PMID 33195246 DOI: 10.3389/fcell.2020.587778  0.68
2016 Kistler M, Muntean A, Szymczak W, Rink N, Fuchs H, Gailus-Durner V, Wurst W, Hoeschen C, Klingenspor M, Hrabě de Angelis M, Rozman J. Diet-induced and mono-genetic obesity alter volatile organic compound signature in mice. Journal of Breath Research. 10: 016009. PMID 26860833 DOI: 10.1088/1752-7155/10/1/016009  0.68
2016 Klafke R, Prem Anand AA, Wurst W, Prakash N, Wizenmann A. Differences in the spatiotemporal expression and epistatic gene regulation of the mesodiencephalic dopaminergic precursor marker PITX3 during chicken and mouse development. Development (Cambridge, England). 143: 691-702. PMID 26755703 DOI: 10.1242/dev.126748  0.68
2016 Nechiporuk T, McGann J, Mullendorff K, Hsieh J, Wurst W, Floss T, Mandel G. The REST remodeling complex protects genomic integrity during embryonic neurogenesis. Elife. 5. PMID 26745185 DOI: 10.7554/eLife.09584  0.68
2015 Hölter SM, Garrett L, Einicke J, Sperling B, Dirscherl P, Zimprich A, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Wurst W. Assessing Cognition in Mice. Current Protocols in Mouse Biology. 5: 331-58. PMID 26629775 DOI: 10.1002/9780470942390.mo150068  0.68
2015 Hölter SM, Einicke J, Sperling B, Zimprich A, Garrett L, Fuchs H, Gailus-Durner V, Hrabé de Angelis M, Wurst W. Tests for Anxiety-Related Behavior in Mice. Current Protocols in Mouse Biology. 5: 291-309. PMID 26629773 DOI: 10.1002/9780470942390.mo150010  0.68
2015 Garrett L, Zhang J, Zimprich A, Niedermeier KM, Fuchs H, Gailus-Durner V, Hrabě de Angelis M, Vogt Weisenhorn D, Wurst W, Hölter SM. Conditional Reduction of Adult Born Doublecortin-Positive Neurons Reversibly Impairs Selective Behaviors. Frontiers in Behavioral Neuroscience. 9: 302. PMID 26617501 DOI: 10.3389/fnbeh.2015.00302  0.68
2015 Fukusumi Y, Meier F, Götz S, Matheus F, Irmler M, Beckervordersandforth R, Faus-Kessler T, Minina E, Rauser B, Zhang J, Arenas E, Andersson E, Niehrs C, Beckers J, Simeone A, ... Wurst W, et al. Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 13385-401. PMID 26424886 DOI: 10.1523/JNEUROSCI.1722-15.2015  0.68
2015 Bender J, Engeholm M, Ederer MS, Breu J, Møller TC, Michalakis S, Rasko T, Wanker EE, Biel M, Martinez KL, Wurst W, Deussing JM. Corticotropin-Releasing Hormone Receptor Type 1 (CRHR1) Clustering with MAGUKs Is Mediated via Its C-Terminal PDZ Binding Motif. Plos One. 10: e0136768. PMID 26352593 DOI: 10.1371/journal.pone.0136768  0.68
2015 Martinez-Ferre A, Lloret-Quesada C, Prakash N, Wurst W, Rubenstein JL, Martinez S. Fgf15 regulates thalamic development by controlling the expression of proneural genes. Brain Structure & Function. PMID 26311466 DOI: 10.1007/s00429-015-1089-5  0.68
2015 Theodorou M, Rauser B, Zhang J, Prakash N, Wurst W, Schick JA. Limitations of in vivo reprogramming to dopaminergic neurons via a tricistronic strategy. Human Gene Therapy Methods. PMID 26107288 DOI: 10.1089/hgtb.2014.152  0.68
2015 Truong DJ, Kühner K, Kühn R, Werfel S, Engelhardt S, Wurst W, Ortiz O. Development of an intein-mediated split-Cas9 system for gene therapy. Nucleic Acids Research. PMID 26082496 DOI: 10.1093/nar/gkv601  0.68
2015 Zhang J, Götz S, Vogt Weisenhorn DM, Simeone A, Wurst W, Prakash N. A WNT1-regulated developmental gene cascade prevents dopaminergic neurodegeneration in adult En1(+/-) mice. Neurobiology of Disease. 82: 32-45. PMID 26049140 DOI: 10.1016/j.nbd.2015.05.015  0.68
2015 Ingold I, Aichler M, Yefremova E, Roveri A, Buday K, Doll S, Tasdemir A, Hoffard N, Wurst W, Walch A, Ursini F, Friedmann Angeli JP, Conrad M. Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility. The Journal of Biological Chemistry. 290: 14668-78. PMID 25922076 DOI: 10.1074/jbc.M115.656363  0.68
2015 Chu VT, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, Kühn R. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nature Biotechnology. 33: 543-8. PMID 25803306 DOI: 10.1038/nbt.3198  0.68
2015 Tischner C, Hofer A, Wulff V, Stepek J, Dumitru I, Becker L, Haack T, Kremer L, Datta AN, Sperl W, Floss T, Wurst W, Chrzanowska-Lightowlers Z, De Angelis MH, Klopstock T, et al. MTO1 mediates tissue specificity of OXPHOS defects via tRNA modification and translation optimization, which can be bypassed by dietary intervention. Human Molecular Genetics. 24: 2247-66. PMID 25552653 DOI: 10.1093/hmg/ddu743  0.68
2015 Washkowitz AJ, Schall C, Zhang K, Wurst W, Floss T, Mager J, Papaioannou VE. Mga is essential for the survival of pluripotent cells during peri-implantation development. Development (Cambridge, England). 142: 31-40. PMID 25516968 DOI: 10.1242/dev.111104  0.68
2015 Seyfarth K, Poschmann G, Rozman J, Fromme T, Rink N, Hofmann A, Wurst W, Stühler K, Klingenspor M. The development of diet-induced obesity and associated metabolic impairments in Dj-1 deficient mice. The Journal of Nutritional Biochemistry. 26: 75-81. PMID 25448609 DOI: 10.1016/j.jnutbio.2014.09.002  0.68
2015 Thor T, Künkele A, Pajtler KW, Wefers AK, Stephan H, Mestdagh P, Heukamp L, Hartmann W, Vandesompele J, Sadowski N, Becker L, Garrett L, Hölter SM, Horsch M, Calzada-Wack J, ... ... Wurst W, et al. MiR-34a deficiency accelerates medulloblastoma formation in vivo. International Journal of Cancer. Journal International Du Cancer. 136: 2293-303. PMID 25348795 DOI: 10.1002/ijc.29294  0.68
2015 Neschen S, Scheerer M, Seelig A, Huypens P, Schultheiss J, Wu M, Wurst W, Rathkolb B, Suhre K, Wolf E, Beckers J, Hrabé de Angelis M. Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice. Diabetes. 64: 284-90. PMID 25071027 DOI: 10.2337/db14-0393  0.68
2015 Saarikangas J, Kourdougli N, Senju Y, Chazal G, Segerstråle M, Minkeviciene R, Kuurne J, Mattila PK, Garrett L, Hölter SM, Becker L, Racz I, Hans W, Klopstock T, Wurst W, et al. MIM-Induced Membrane Bending Promotes Dendritic Spine Initiation Developmental Cell. 33: 644-659. DOI: 10.1016/j.devcel.2015.04.014  0.68
2015 Martinez-Ferre A, Lloret-Quesada C, Prakash N, Wurst W, Rubenstein JLR, Martinez S. Fgf15 regulates thalamic development by controlling the expression of proneural genes Brain Structure and Function. DOI: 10.1007/s00429-015-1089-5  0.68
2015 Rosen B, Schick J, Wurst W. Beyond knockouts: the International Knockout Mouse Consortium delivers modular and evolving tools for investigating mammalian genes Mammalian Genome. DOI: 10.1007/s00335-015-9598-3  0.68
2014 Becker L, Kling E, Schiller E, Zeh R, Schrewe A, Hölter SM, Mossbrugger I, Calzada-Wack J, Strecker V, Wittig I, Dumitru I, Wenz T, Bender A, Aichler M, Janik D, ... ... Wurst W, et al. MTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy. Plos One. 9: e114918. PMID 25506927 DOI: 10.1371/journal.pone.0114918  0.68
2014 Gewies A, Gorka O, Bergmann H, Pechloff K, Petermann F, Jeltsch KM, Rudelius M, Kriegsmann M, Weichert W, Horsch M, Beckers J, Wurst W, Heikenwalder M, Korn T, Heissmeyer V, et al. Uncoupling Malt1 threshold function from paracaspase activity results in destructive autoimmune inflammation. Cell Reports. 9: 1292-305. PMID 25456129 DOI: 10.1016/j.celrep.2014.10.044  0.68
2014 Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trümbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo D. MicroRNA-9 controls dendritic development by targeting REST. Elife. 3. PMID 25406064 DOI: 10.7554/eLife.02755  0.68
2014 Matthes M, Preusse M, Zhang J, Schechter J, Mayer D, Lentes B, Theis F, Prakash N, Wurst W, Trümbach D. Mouse IDGenes: a reference database for genetic interactions in the developing mouse brain. Database : the Journal of Biological Databases and Curation. 2014. PMID 25145340 DOI: 10.1093/database/bau083  0.68
2014 Kraus P, V S, Yu HB, Xing X, Lim SL, Adler T, Pimentel JA, Becker L, Bohla A, Garrett L, Hans W, Hölter SM, Janas E, Moreth K, Prehn C, ... ... Wurst W, et al. Pleiotropic functions for transcription factor zscan10. Plos One. 9: e104568. PMID 25111779 DOI: 10.1371/journal.pone.0104568  0.68
2014 Blanco S, Dietmann S, Flores JV, Hussain S, Kutter C, Humphreys P, Lukk M, Lombard P, Treps L, Popis M, Kellner S, Hölter SM, Garrett L, Wurst W, Becker L, et al. Aberrant methylation of tRNAs links cellular stress to neuro-developmental disorders. The Embo Journal. 33: 2020-39. PMID 25063673 DOI: 10.15252/embj.201489282  0.68
2014 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Hölter SM, Kühn R, Weisenhorn DM, Wurst W, Prakash N. FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. Plos One. 9: e101124. PMID 24983448 DOI: 10.1371/journal.pone.0101124  0.68
2014 Zumbrennen-Bullough KB, Becker L, Garrett L, Hölter SM, Calzada-Wack J, Mossbrugger I, Quintanilla-Fend L, Racz I, Rathkolb B, Klopstock T, Wurst W, Zimmer A, Wolf E, Fuchs H, Gailus-Durner V, et al. Abnormal brain iron metabolism in Irp2 deficient mice is associated with mild neurological and behavioral impairments. Plos One. 9: e98072. PMID 24896637 DOI: 10.1371/journal.pone.0098072  0.68
2014 Pertek A, Meier F, Irmler M, Beckers J, Skylaki S, Endele M, Wurst W, Prakash N, Kühn R. Simple derivation of transgene-free iPS cells by a dual recombinase approach. Molecular Biotechnology. 56: 697-713. PMID 24677035 DOI: 10.1007/s12033-014-9748-y  0.68
2014 Spieler D, Kaffe M, Knauf F, Bessa J, Tena JJ, Giesert F, Schormair B, Tilch E, Lee H, Horsch M, Czamara D, Karbalai N, von Toerne C, Waldenberger M, Gieger C, ... ... Wurst W, et al. Restless legs syndrome-associated intronic common variant in Meis1 alters enhancer function in the developing telencephalon. Genome Research. 24: 592-603. PMID 24642863 DOI: 10.1101/gr.166751.113  0.68
2014 Stribl C, Samara A, Trümbach D, Peis R, Neumann M, Fuchs H, Gailus-Durner V, HrabÄ› de Angelis M, Rathkolb B, Wolf E, Beckers J, Horsch M, Neff F, Kremmer E, Koob S, ... ... Wurst W, et al. Mitochondrial dysfunction and decrease in body weight of a transgenic knock-in mouse model for TDP-43. The Journal of Biological Chemistry. 289: 10769-84. PMID 24515116 DOI: 10.1074/jbc.M113.515940  0.68
2014 Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A. Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Development (Cambridge, England). 141: 377-88. PMID 24335253 DOI: 10.1242/dev.102954  0.68
2014 Wurst W, Prakash N. Wnt1-regulated genetic networks in midbrain dopaminergic neuron development. Journal of Molecular Cell Biology. 6: 34-41. PMID 24326514 DOI: 10.1093/jmcb/mjt046  0.68
2014 Zimprich A, Garrett L, Deussing JM, Wotjak CT, Fuchs H, Gailus-Durner V, Angelis MHd, Wurst W, Hölter SM. A robust and reliable non-invasive test for stress responsivity in mice Frontiers in Behavioral Neuroscience. 8. DOI: 10.3389/fnbeh.2014.00125  0.68
2014 Fuchs H, Neschen S, Rozman J, Rathkolb B, Wagner S, Adler T, Afonso L, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Frankó A, Garrett L, Glasl L, ... ... Wurst W, et al. Mouse genetics and metabolic mouse phenotyping Genetics Meets Metabolomics: From Experiment to Systems Biology. 85-106. DOI: 10.1007/978-1-4614-1689-0_7  0.68
2013 Spanagel R, Durstewitz D, Hansson A, Heinz A, Kiefer F, Köhr G, Matthäus F, Nöthen MM, Noori HR, Obermayer K, Rietschel M, Schloss P, Scholz H, Schumann G, Smolka M, ... ... Wurst W, et al. A systems medicine research approach for studying alcohol addiction. Addiction Biology. 18: 883-96. PMID 24283978 DOI: 10.1111/adb.12109  0.68
2013 Häbig K, Gellhaar S, Heim B, Djuric V, Giesert F, Wurst W, Walter C, Hentrich T, Riess O, Bonin M. LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4. Biochimica Et Biophysica Acta. 1832: 2352-67. PMID 24075941 DOI: 10.1016/j.bbadis.2013.09.009  0.68
2013 Panda SK, Wefers B, Ortiz O, Floss T, Schmid B, Haass C, Wurst W, Kühn R. Highly efficient targeted mutagenesis in mice using TALENs. Genetics. 195: 703-13. PMID 23979585 DOI: 10.1534/genetics.113.156570  0.68
2013 Simon MM, Greenaway S, White JK, Fuchs H, Gailus-Durner V, Wells S, Sorg T, Wong K, Bedu E, Cartwright EJ, Dacquin R, Djebali S, Estabel J, Graw J, Ingham NJ, ... ... Wurst W, et al. A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains. Genome Biology. 14: R82. PMID 23902802 DOI: 10.1186/gb-2013-14-7-r82  0.68
2013 Neff F, Flores-Dominguez D, Ryan DP, Horsch M, Schröder S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Garrett L, Hans W, Hettich MM, Holtmeier R, Hölter SM, Moreth K, ... ... Wurst W, et al. Rapamycin extends murine lifespan but has limited effects on aging. The Journal of Clinical Investigation. 123: 3272-91. PMID 23863708 DOI: 10.1172/JCI67674  0.68
2013 Hock S, Ng YK, Hasenauer J, Wittmann D, Lutter D, Trümbach D, Wurst W, Prakash N, Theis FJ. Sharpening of expression domains induced by transcription and microRNA regulation within a spatio-temporal model of mid-hindbrain boundary formation. Bmc Systems Biology. 7: 48. PMID 23799959 DOI: 10.1186/1752-0509-7-48  0.68
2013 Giesert F, Hofmann A, Bürger A, Zerle J, Kloos K, Hafen U, Ernst L, Zhang J, Vogt-Weisenhorn DM, Wurst W. Expression analysis of Lrrk1, Lrrk2 and Lrrk2 splice variants in mice. Plos One. 8: e63778. PMID 23675505 DOI: 10.1371/journal.pone.0063778  0.68
2013 Wang XD, Su YA, Wagner KV, Avrabos C, Scharf SH, Hartmann J, Wolf M, Liebl C, Kühne C, Wurst W, Holsboer F, Eder M, Deussing JM, Müller MB, Schmidt MV. Nectin-3 links CRHR1 signaling to stress-induced memory deficits and spine loss. Nature Neuroscience. 16: 706-13. PMID 23644483 DOI: 10.1038/nn.3395  0.68
2013 Kugler JE, Horsch M, Huang D, Furusawa T, Rochman M, Garrett L, Becker L, Bohla A, Hölter SM, Prehn C, Rathkolb B, Racz I, Aguilar-Pimentel JA, Adler T, Adamski J, ... ... Wurst W, et al. High mobility group N proteins modulate the fidelity of the cellular transcriptional profile in a tissue- and variant-specific manner. The Journal of Biological Chemistry. 288: 16690-703. PMID 23620591 DOI: 10.1074/jbc.M113.463315  0.68
2013 Müller-Rischart AK, Pilsl A, Beaudette P, Patra M, Hadian K, Funke M, Peis R, Deinlein A, Schweimer C, Kuhn PH, Lichtenthaler SF, Motori E, Hrelia S, Wurst W, Trümbach D, et al. The E3 ligase parkin maintains mitochondrial integrity by increasing linear ubiquitination of NEMO. Molecular Cell. 49: 908-21. PMID 23453807 DOI: 10.1016/j.molcel.2013.01.036  0.68
2013 Di Giovannantonio LG, Di Salvio M, Acampora D, Prakash N, Wurst W, Simeone A. Otx2 selectively controls the neurogenesis of specific neuronal subtypes of the ventral tegmental area and compensates En1-dependent neuronal loss and MPTP vulnerability. Developmental Biology. 373: 176-83. PMID 23117062 DOI: 10.1016/j.ydbio.2012.10.022  0.68
2013 Bolze F, Rink N, Brumm H, Kühn R, Mocek S, Schwarz AE, Kless C, Biebermann H, Wurst W, Rozman J, Klingenspor M. Characterization of the melanocortin-4-receptor nonsense mutation W16X in vitro and in vivo. The Pharmacogenomics Journal. 13: 80-93. PMID 21969101 DOI: 10.1038/tpj.2011.43  0.68
2012 Mellett M, Atzei P, Horgan A, Hams E, Floss T, Wurst W, Fallon PG, Moynagh PN. Orphan receptor IL-17RD tunes IL-17A signalling and is required for neutrophilia. Nature Communications. 3: 1119. PMID 23047677 DOI: 10.1038/ncomms2127  0.68
2012 Bradley A, Anastassiadis K, Ayadi A, Battey JF, Bell C, Birling MC, Bottomley J, Brown SD, Bürger A, Bult CJ, Bushell W, Collins FS, Desaintes C, Doe B, Economides A, ... ... Wurst W, et al. The mammalian gene function resource: the International Knockout Mouse Consortium. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 580-6. PMID 22968824 DOI: 10.1007/s00335-012-9422-2  0.68
2012 Fuchs H, Gailus-Durner V, Neschen S, Adler T, Afonso LC, Aguilar-Pimentel JA, Becker L, Bohla A, Calzada-Wack J, Cohrs C, Dewert A, Fridrich B, Garrett L, Glasl L, Götz A, ... ... Wurst W, et al. Innovations in phenotyping of mouse models in the German Mouse Clinic. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 23: 611-22. PMID 22926221 DOI: 10.1007/s00335-012-9415-1  0.68
2012 Augustin R, Endres K, Reinhardt S, Kuhn PH, Lichtenthaler SF, Hansen J, Wurst W, Trümbach D. Computational identification and experimental validation of microRNAs binding to the Alzheimer-related gene ADAM10. Bmc Medical Genetics. 13: 35. PMID 22594617 DOI: 10.1186/1471-2350-13-35  0.68
2012 Molander A, Vengeliene V, Heilig M, Wurst W, Deussing JM, Spanagel R. Brain-specific inactivation of the Crhr1 gene inhibits post-dependent and stress-induced alcohol intake, but does not affect relapse-like drinking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 1047-56. PMID 22113086 DOI: 10.1038/npp.2011.297  0.68
2012 Thoeringer CK, Henes K, Eder M, Dahlhoff M, Wurst W, Holsboer F, Deussing JM, Moosmang S, Wotjak CT. Consolidation of remote fear memories involves Corticotropin-Releasing Hormone (CRH) receptor type 1-mediated enhancement of AMPA receptor GluR1 signaling in the dentate gyrus. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 787-96. PMID 22030710 DOI: 10.1038/npp.2011.256  0.68
2011 Rolyan H, Scheffold A, Heinrich A, Begus-Nahrmann Y, Langkopf BH, Hölter SM, Vogt-Weisenhorn DM, Liss B, Wurst W, Lie DC, Thal DR, Biber K, Rudolph KL. Telomere shortening reduces Alzheimer's disease amyloid pathology in mice. Brain : a Journal of Neurology. 134: 2044-56. PMID 21672962 DOI: 10.1093/brain/awr133  0.68
2011 Horsch M, Seeburg PH, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Garrett L, Götz A, Hans W, Higuchi M, Hölter SM, Naton B, Prehn C, Puk O, Rácz I, ... ... Wurst W, et al. Requirement of the RNA-editing enzyme ADAR2 for normal physiology in mice. The Journal of Biological Chemistry. 286: 18614-22. PMID 21467037 DOI: 10.1074/jbc.M110.200881  0.68
2011 Abe K, Fuchs H, Boersma A, Hans W, Yu P, Kalaydjiev S, Klaften M, Adler T, Calzada-Wack J, Mossbrugger I, Rathkolb B, Rozman J, Prehn C, Maraslioglu M, Kametani Y, ... ... Wurst W, et al. A novel N-ethyl-N-nitrosourea-induced mutation in phospholipase Cγ2 causes inflammatory arthritis, metabolic defects, and male infertility in vitro in a murine model. Arthritis and Rheumatism. 63: 1301-11. PMID 21305534 DOI: 10.1002/art.30280  0.68
2011 Schnütgen F, Ehrmann F, Poser I, Hubner NC, Hansen J, Floss T, deVries I, Wurst W, Hyman A, Mann M, von Melchner H. Resources for proteomics in mouse embryonic stem cells. Nature Methods. 8: 103-4. PMID 21278719 DOI: 10.1038/nmeth0211-103  0.68
2011 Friedel RH, Wurst W, Wefers B, Kühn R. Generating conditional knockout mice Methods in Molecular Biology (Clifton, N.J.). 693: 205-231. PMID 21080282 DOI: 10.1007/978-1-60761-974-1_12  0.68
2011 Fuchs H, Gailus-Durner V, Adler T, Aguilar-Pimentel JA, Becker L, Calzada-Wack J, Da Silva-Buttkus P, Neff F, Götz A, Hans W, Hölter SM, Horsch M, Kastenmüller G, Kemter E, Lengger C, ... ... Wurst W, et al. Mouse phenotyping. Methods (San Diego, Calif.). 53: 120-35. PMID 20708688 DOI: 10.1016/j.ymeth.2010.08.006  0.68
2010 Zhang J, Giesert F, Kloos K, Vogt Weisenhorn DM, Aigner L, Wurst W, Couillard-Despres S. A powerful transgenic tool for fate mapping and functional analysis of newly generated neurons. Bmc Neuroscience. 11: 158. PMID 21194452 DOI: 10.1186/1471-2202-11-158  0.68
2010 Trümbach D, Graf C, Pütz B, Kühne C, Panhuysen M, Weber P, Holsboer F, Wurst W, Welzl G, Deussing JM. Deducing corticotropin-releasing hormone receptor type 1 signaling networks from gene expression data by usage of genetic algorithms and graphical Gaussian models. Bmc Systems Biology. 4: 159. PMID 21092110 DOI: 10.1186/1752-0509-4-159  0.68
2010 Tsolakidou A, Czibere L, Pütz B, Trümbach D, Panhuysen M, Deussing JM, Wurst W, Sillaber I, Landgraf R, Holsboer F, Rein T. Gene expression profiling in the stress control brain region hypothalamic paraventricular nucleus reveals a novel gene network including amyloid beta precursor protein. Bmc Genomics. 11: 546. PMID 20932279 DOI: 10.1186/1471-2164-11-546  0.68
2010 Shimokawa N, Haglund K, Hölter SM, Grabbe C, Kirkin V, Koibuchi N, Schultz C, Rozman J, Hoeller D, Qiu CH, Londoño MB, Ikezawa J, Jedlicka P, Stein B, Schwarzacher SW, ... ... Wurst W, et al. CIN85 regulates dopamine receptor endocytosis and governs behaviour in mice. The Embo Journal. 29: 2421-32. PMID 20551902 DOI: 10.1038/emboj.2010.120  0.68
2010 Cox BJ, Vollmer M, Tamplin O, Lu M, Biechele S, Gertsenstein M, van Campenhout C, Floss T, Kühn R, Wurst W, Lickert H, Rossant J. Phenotypic annotation of the mouse X chromosome. Genome Research. 20: 1154-64. PMID 20548051 DOI: 10.1101/gr.105106.110  0.68
2010 Romanowski CP, Fenzl T, Flachskamm C, Wurst W, Holsboer F, Deussing JM, Kimura M. Central deficiency of corticotropin-releasing hormone receptor type 1 (CRH-R1) abolishes effects of CRH on NREM but not on REM sleep in mice. Sleep. 33: 427-36. PMID 20394311 DOI: 10.1093/SLEEP/33.4.427  0.68
2010 Castelo-Branco G, Andersson ER, Minina E, Sousa KM, Ribeiro D, Kokubu C, Imai K, Prakash N, Wurst W, Arenas E. Delayed dopaminergic neuron differentiation in Lrp6 mutant mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 211-21. PMID 19795519 DOI: 10.1002/dvdy.22094  0.68
2010 Kimura M, Müller-Preuss P, Lu A, Wiesner E, Flachskamm C, Wurst W, Holsboer F, Deussing JM. Conditional corticotropin-releasing hormone overexpression in the mouse forebrain enhances rapid eye movement sleep. Molecular Psychiatry. 15: 154-65. PMID 19455148 DOI: 10.1038/mp.2009.46  0.68
2010 Wurst W, Prakash N. Genetic Control of Meso-diencephalic Dopaminergic Neuron Development in Rodents Dopamine Handbook. DOI: 10.1093/acprof:oso/9780195373035.003.0010  0.68
2009 Morais VA, Verstreken P, Roethig A, Smet J, Snellinx A, Vanbrabant M, Haddad D, Frezza C, Mandemakers W, Vogt-Weisenhorn D, Van Coster R, Wurst W, Scorrano L, De Strooper B. Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function. Embo Molecular Medicine. 1: 99-111. PMID 20049710 DOI: 10.1002/emmm.200900006  0.68
2009 Wittmann DM, Blöchl F, Trümbach D, Wurst W, Prakash N, Theis FJ. Spatial analysis of expression patterns predicts genetic interactions at the mid-hindbrain boundary. Plos Computational Biology. 5: e1000569. PMID 19936059 DOI: 10.1371/journal.pcbi.1000569  0.68
2009 Wizenmann A, Brunet I, Lam JS, Sonnier L, Beurdeley M, Zarbalis K, Weisenhorn-Vogt D, Weinl C, Dwivedy A, Joliot A, Wurst W, Holt C, Prochiantz A. Extracellular Engrailed participates in the topographic guidance of retinal axons in vivo. Neuron. 64: 355-66. PMID 19914184 DOI: 10.1016/j.neuron.2009.09.018  0.68
2009 Brown SD, Wurst W, Kühn R, Hancock JM. The functional annotation of mammalian genomes: the challenge of phenotyping. Annual Review of Genetics. 43: 305-33. PMID 19689210 DOI: 10.1146/annurev-genet-102108-134143  0.68
2009 Webb KJ, Norton WH, Trümbach D, Meijer AH, Ninkovic J, Topp S, Heck D, Marr C, Wurst W, Theis FJ, Spaink HP, Bally-Cuif L. Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine. Genome Biology. 10: R81. PMID 19646228 DOI: 10.1186/gb-2009-10-7-r81  0.68
2009 Lutz AK, Exner N, Fett ME, Schlehe JS, Kloos K, Lämmermann K, Brunner B, Kurz-Drexler A, Vogel F, Reichert AS, Bouman L, Vogt-Weisenhorn D, Wurst W, Tatzelt J, Haass C, et al. Loss of parkin or PINK1 function increases Drp1-dependent mitochondrial fragmentation. The Journal of Biological Chemistry. 284: 22938-51. PMID 19546216 DOI: 10.1074/jbc.M109.035774  0.68
2009 Liebl C, Panhuysen M, Pütz B, Trümbach D, Wurst W, Deussing JM, Müller MB, Schmidt MV. Gene expression profiling following maternal deprivation: involvement of the brain Renin-Angiotensin system. Frontiers in Molecular Neuroscience. 2: 1. PMID 19506703 DOI: 10.3389/neuro.02.001.2009  0.68
2009 Gailus-Durner V, Fuchs H, Adler T, Aguilar Pimentel A, Becker L, Bolle I, Calzada-Wack J, Dalke C, Ehrhardt N, Ferwagner B, Hans W, Hölter SM, Hölzlwimmer G, Horsch M, Javaheri A, ... ... Wurst W, et al. Systemic first-line phenotyping. Methods in Molecular Biology (Clifton, N.J.). 530: 463-509. PMID 19266331 DOI: 10.1007/978-1-59745-471-1_25  0.68
2008 Söker T, Dalke C, Puk O, Floss T, Becker L, Bolle I, Favor J, Hans W, Hölter SM, Horsch M, Kallnik M, Kling E, Moerth C, Schrewe A, Stigloher C, ... ... Wurst W, et al. Pleiotropic effects in Eya3 knockout mice. Bmc Developmental Biology. 8: 118. PMID 19102749 DOI: 10.1186/1471-213X-8-118  0.68
2008 Andersson ER, Prakash N, Cajanek L, Minina E, Bryja V, Bryjova L, Yamaguchi TP, Hall AC, Wurst W, Arenas E. Wnt5a regulates ventral midbrain morphogenesis and the development of A9-A10 dopaminergic cells in vivo. Plos One. 3: e3517. PMID 18953410 DOI: 10.1371/journal.pone.0003517  0.68
2008 Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM. Conditional CRH overexpressing mice: an animal model for stress-elicited pathologies and treatments that target the central CRH system. Molecular Psychiatry. 13: 989. PMID 18936754 DOI: 10.1038/mp.2008.107  0.68
2008 Lu A, Steiner MA, Whittle N, Vogl AM, Walser SM, Ableitner M, Refojo D, Ekker M, Rubenstein JL, Stalla GK, Singewald N, Holsboer F, Wotjak CT, Wurst W, Deussing JM. Conditional mouse mutants highlight mechanisms of corticotropin-releasing hormone effects on stress-coping behavior. Molecular Psychiatry. 13: 1028-42. PMID 18475271 DOI: 10.1038/mp.2008.51  0.68
2008 Ganguly K, Favor J, Neuhäuser-Klaus A, Sandulache R, Puk O, Beckers J, Horsch M, Schädler S, Vogt Weisenhorn D, Wurst W, Graw J. Novel allele of crybb2 in the mouse and its expression in the brain. Investigative Ophthalmology & Visual Science. 49: 1533-41. PMID 18385073 DOI: 10.1167/iovs.07-0788  0.68
2007 Konstantinova I, Nikolova G, Ohara-Imaizumi M, Meda P, Kucera T, Zarbalis K, Wurst W, Nagamatsu S, Lammert E. EphA-Ephrin-A-mediated beta cell communication regulates insulin secretion from pancreatic islets. Cell. 129: 359-70. PMID 17448994 DOI: 10.1016/j.cell.2007.02.044  0.68
2007 Collins FS, Finnell RH, Rossant J, Wurst W. A new partner for the international knockout mouse consortium. Cell. 129: 235. PMID 17448981 DOI: 10.1016/j.cell.2007.04.007  0.68
2007 Kallnik M, Elvert R, Ehrhardt N, Kissling D, Mahabir E, Welzl G, Faus-Kessler T, de Angelis MH, Wurst W, Schmidt J, Hölter SM. Impact of IVC housing on emotionality and fear learning in male C3HeB/FeJ and C57BL/6J mice. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 173-86. PMID 17431719 DOI: 10.1007/s00335-007-9002-z  0.68
2007 Görner K, Holtorf E, Waak J, Pham TT, Vogt-Weisenhorn DM, Wurst W, Haass C, Kahle PJ. Structural determinants of the C-terminal helix-kink-helix motif essential for protein stability and survival promoting activity of DJ-1. The Journal of Biological Chemistry. 282: 13680-91. PMID 17331951 DOI: 10.1074/jbc.M609821200  0.68
2007 Schierloh A, Deussing J, Wurst W, Zieglgänsberger W, Rammes G. Corticotropin-releasing factor (CRF) receptor type 1-dependent modulation of synaptic plasticity. Neuroscience Letters. 416: 82-6. PMID 17316992 DOI: 10.1016/j.neulet.2007.01.047  0.68
2006 Plath N, Ohana O, Dammermann B, Errington ML, Schmitz D, Gross C, Mao X, Engelsberg A, Mahlke C, Welzl H, Kobalz U, Stawrakakis A, Fernandez E, Waltereit R, Bick-Sander A, ... ... Wurst W, et al. Arc/Arg3.1 is essential for the consolidation of synaptic plasticity and memories. Neuron. 52: 437-44. PMID 17088210 DOI: 10.1016/j.neuron.2006.08.024  0.68
2006 Grad I, McKee TA, Ludwig SM, Hoyle GW, Ruiz P, Wurst W, Floss T, Miller CA, Picard D. The Hsp90 cochaperone p23 is essential for perinatal survival. Molecular and Cellular Biology. 26: 8976-83. PMID 17000766 DOI: 10.1128/MCB.00734-06  0.68
2006 Beekman C, Nichane M, De Clercq S, Maetens M, Floss T, Wurst W, Bellefroid E, Marine JC. Evolutionarily conserved role of nucleostemin: Controlling proliferation of stem/progenitor cells during early vertebrate development Molecular and Cellular Biology. 26: 9291-9301. PMID 17000755 DOI: 10.1128/MCB.01183-06  0.68
2006 Nguyen NK, Keck ME, Hetzenauer A, Thoeringer CK, Wurst W, Deussing JM, Holsboer F, Müller MB, Singewald N. Conditional CRF receptor 1 knockout mice show altered neuronal activation pattern to mild anxiogenic challenge. Psychopharmacology. 188: 374-85. PMID 16953386 DOI: 10.1007/s00213-006-0513-1  0.68
2006 Poët M, Kornak U, Schweizer M, Zdebik AA, Scheel O, Hoelter S, Wurst W, Schmitt A, Fuhrmann JC, Planells-Cases R, Mole SE, Hübner CA, Jentsch TJ. Lysosomal storage disease upon disruption of the neuronal chloride transport protein ClC-6. Proceedings of the National Academy of Sciences of the United States of America. 103: 13854-9. PMID 16950870 DOI: 10.1073/pnas.0606137103  0.68
2006 Prakash N, Wurst W. Development of dopaminergic neurons in the mammalian brain. Cellular and Molecular Life Sciences : Cmls. 63: 187-206. PMID 16389456 DOI: 10.1007/s00018-005-5387-6  0.68
2006 Nord AS, Chang PJ, Conklin BR, Cox AV, Harper CA, Hicks GG, Huang CC, Johns SJ, Kawamoto M, Liu S, Meng EC, Morris JH, Rossant J, Ruiz P, Skarnes WC, ... ... Wurst W, et al. The International Gene Trap Consortium Website: a portal to all publicly available gene trap cell lines in mouse. Nucleic Acids Research. 34: D642-8. PMID 16381950 DOI: 10.1093/nar/gkj097  0.68
2006 Prakash N, Brodski C, Naserke T, Puelles E, Gogoi R, Hall A, Panhuysen M, Echevarria D, Sussel L, Weisenhorn DM, Martinez S, Arenas E, Simeone A, Wurst W. A Wnt1-regulated genetic network controls the identity and fate of midbrain-dopaminergic progenitors in vivo. Development (Cambridge, England). 133: 89-98. PMID 16339193 DOI: 10.1242/dev.02181  0.68
2005 Hölter SM, Kallnik M, Wurst W, Marsicano G, Lutz B, Wotjak CT. Cannabinoid CB1 receptor is dispensable for memory extinction in an appetitively-motivated learning task European Journal of Pharmacology. 510: 69-74. PMID 15740726 DOI: 10.1016/j.ejphar.2005.01.008  0.68
2004 Austin CP, Battey JF, Bradley A, Bucan M, Capecchi M, Collins FS, Dove WF, Duyk G, Dymecki S, Eppig JT, Grieder FB, Heintz N, Hicks G, Insel TR, Joyner A, ... ... Wurst W, et al. The knockout mouse project. Nature Genetics. 36: 921-4. PMID 15340423 DOI: 10.1038/ng0904-921  0.68
2004 Skarnes WC, von Melchner H, Wurst W, Hicks G, Nord AS, Cox T, Young SG, Ruiz P, Soriano P, Tessier-Lavigne M, Conklin BR, Stanford WL, Rossant J. A public gene trap resource for mouse functional genomics. Nature Genetics. 36: 543-4. PMID 15167922 DOI: 10.1038/ng0604-543  0.68
2004 Kwan KM, Li AG, Wang XJ, Wurst W, Behringer RR. Essential roles of BMPR-IA signaling in differentiation and growth of hair follicles and in skin tumorigenesis Genesis. 39: 10-25. PMID 15124223 DOI: 10.1002/gene.20021  0.68
2003 Trokovic R, Trokovic N, Hernesniemi S, Pirvola U, Vogt Weisenhorn DM, Rossant J, McMahon AP, Wurst W, Partanen J. FGFR1 is independently required in both developing mid- and hindbrain for sustained response to isthmic signals. The Embo Journal. 22: 1811-23. PMID 12682014 DOI: 10.1093/emboj/cdg169  0.68
2001 Müller MB, Preil J, Renner U, Zimmermann S, Kresse AE, Stalla GK, Keck ME, Holsboer F, Wurst W. Expression of CRHR1 and CRHR2 in mouse pituitary and adrenal gland: implications for HPA system regulation. Endocrinology. 142: 4150-3. PMID 11517194 DOI: 10.1210/endo.142.9.8491  0.68
2001 Cahana A, Escamez T, Nowakowski RS, Hayes NL, Giacobini M, von Holst A, Shmueli O, Sapir T, McConnell SK, Wurst W, Martinez S, Reiner O. Targeted mutagenesis of Lis1 disrupts cortical development and LIS1 homodimerization. Proceedings of the National Academy of Sciences of the United States of America. 98: 6429-34. PMID 11344260 DOI: 10.1073/pnas.101122598  0.68
2000 Müller MB, Landgraf R, Preil J, Sillaber I, Kresse AE, Keck ME, Zimmermann S, Holsboer F, Wurst W. Selective activation of the hypothalamic vasopressinergic system in mice deficient for the corticotropin-releasing hormone receptor 1 is dependent on glucocorticoids. Endocrinology. 141: 4262-9. PMID 11089561 DOI: 10.1210/endo.141.11.7767  0.68
2000 Mainguy G, Montesinos ML, Lesaffre B, Zevnik B, Karasawa M, Kothary R, Wurst W, Prochiantz A, Volovitch M. An induction gene trap for identifying a homeoprotein-regulated locus. Nature Biotechnology. 18: 746-9. PMID 10888842 DOI: 10.1038/77312  0.68
1998 Sam M, Wurst W, Klüppel M, Jin O, Heng H, Bernstein A. Aquarius, a novel gene isolated by gene trapping with an RNA-dependent RNA polymerase motif Developmental Dynamics. 212: 304-317. PMID 9626505 DOI: 10.1002/(SICI)1097-0177(199806)212:2<304::AID-AJA15>3.0.CO;2-3  0.68
1996 Sam M, Wurst W, Forrester L, Vauti F, Heng H, Bernstein A. A novel family of repeat sequences in the mouse genome responsive to retinoic acid. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 7: 741-8. PMID 8854861 DOI: 10.1007/s003359900224  0.68
1996 Loomis CA, Harris E, Michaud J, Wurst W, Hanks M, Joyner AL. The mouse Engrailed-1 gene and ventral limb patterning. Nature. 382: 360-3. PMID 8684466 DOI: 10.1038/382360a0  0.68
1996 Forrester LM, Nagy A, Sam M, Watt A, Stevenson L, Bernstein A, Joyner AL, Wurst W. An induction gene trap screen in embryonic stem cells: Identification of genes that respond to retinoic acid in vitro. Proceedings of the National Academy of Sciences of the United States of America. 93: 1677-82. PMID 8643689 DOI: 10.1073/pnas.93.4.1677  0.68
1993 Hill DP, Wurst W. Gene and enhancer trapping: mutagenic strategies for developmental studies Current Topics in Developmental Biology. 28: 181-206. PMID 8348841 DOI: 10.1016/S0070-2153(08)60213-6  0.68
1993 Hill DP, Wurst W. Screening for novel pattern formation genes using gene trap approaches Methods in Enzymology. 225: 664-681. PMID 8231878 DOI: 10.1016/0076-6879(93)25043-2  0.68
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