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Mary Hensler - Publications

Affiliations: 
2003-2008 Pediatrics University of California, San Diego, La Jolla, CA 
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Mascuch SJ, Boudreau PD, Carland TM, Pierce NT, Olson J, Hensler ME, Choi H, Campanale J, Hamdoun A, Nizet V, Gerwick WH, Gaasterland T, Gerwick L. Marine Natural Product Honaucin A Attenuates Inflammation by Activating the Nrf2-ARE Pathway. Journal of Natural Products. PMID 29215273 DOI: 10.1021/Acs.Jnatprod.7B00734  0.421
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens. Ebiomedicine. 2: 690-8. PMID 26288841 DOI: 10.1016/J.Ebiom.2015.05.021  0.779
2015 Harbut MB, Vilchèze C, Luo X, Hensler ME, Guo H, Yang B, Chatterjee AK, Nizet V, Jacobs WR, Schultz PG, Wang F. Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 112: 4453-8. PMID 25831516 DOI: 10.1073/Pnas.1504022112  0.648
2015 Lin L, Nonejuie P, Munguia J, Hollands A, Olson J, Dam Q, Kumaraswamy M, Rivera H, Corriden R, Rohde M, Hensler ME, Burkart MD, Pogliano J, Sakoulas G, Nizet V. Azithromycin Synergizes with Cationic Antimicrobial Peptides to Exert Bactericidal and Therapeutic Activity Against Highly Multidrug-Resistant Gram-Negative Bacterial Pathogens Ebiomedicine. DOI: 10.1016/j.ebiom.2015.05.021  0.764
2014 Fair RJ, McCoy LS, Hensler ME, Aguilar B, Nizet V, Tor Y. Singly modified amikacin and tobramycin derivatives show increased rRNA A-site binding and higher potency against resistant bacteria. Chemmedchem. 9: 2164-71. PMID 25055981 DOI: 10.1002/Cmdc.201402175  0.751
2014 Liu Y, Haste NM, Thienphrapa W, Li J, Nizet V, Hensler M, Li R. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (III). Marine Drugs. 12: 2458-70. PMID 24796304 DOI: 10.3390/md12052458  0.819
2014 Hensler ME, Jang KH, Thienphrapa W, Vuong L, Tran DN, Soubih E, Lin L, Haste NM, Cunningham ML, Kwan BP, Shaw KJ, Fenical W, Nizet V. Anthracimycin activity against contemporary methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 67: 549-53. PMID 24736856 DOI: 10.1038/Ja.2014.36  0.823
2014 Sakoulas G, Okumura CY, Thienphrapa W, Olson J, Nonejuie P, Dam Q, Dhand A, Pogliano J, Yeaman MR, Hensler ME, Bayer AS, Nizet V. Nafcillin enhances innate immune-mediated killing of methicillin-resistant Staphylococcus aureus. Journal of Molecular Medicine (Berlin, Germany). 92: 139-49. PMID 24297496 DOI: 10.1007/S00109-013-1100-7  0.83
2013 Zhu W, Zhang Y, Sinko W, Hensler ME, Olson J, Molohon KJ, Lindert S, Cao R, Li K, Wang K, Wang Y, Liu YL, Sankovsky A, de Oliveira CA, Mitchell DA, et al. Antibacterial drug leads targeting isoprenoid biosynthesis. Proceedings of the National Academy of Sciences of the United States of America. 110: 123-8. PMID 23248302 DOI: 10.1073/Pnas.1219899110  0.568
2012 Haste NM, Thienphrapa W, Tran DN, Loesgen S, Sun P, Nam SJ, Jensen PR, Fenical W, Sakoulas G, Nizet V, Hensler ME. Activity of the thiopeptide antibiotic nosiheptide against contemporary strains of methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 65: 593-8. PMID 23047246 DOI: 10.1038/Ja.2012.77  0.823
2012 Bebien M, Hensler ME, Davanture S, Hsu LC, Karin M, Park JM, Alexopoulou L, Liu GY, Nizet V, Lawrence T. The pore-forming toxin β hemolysin/cytolysin triggers p38 MAPK-dependent IL-10 production in macrophages and inhibits innate immunity. Plos Pathogens. 8: e1002812. PMID 22829768 DOI: 10.1371/Journal.Ppat.1002812  0.581
2012 Liu Y, Haste NM, Thienphrapa W, Nizet V, Hensler M, Li R. Marinopyrrole derivatives as potential antibiotic agents against methicillin-resistant Staphylococcus aureus (I). Marine Drugs. 10: 953-62. PMID 22690153 DOI: 10.3390/Md10040953  0.822
2012 Zhang Y, Fu-Yang Lin, Li K, Zhu W, Liu YL, Cao R, Pang R, Lee E, Axelson J, Hensler M, Wang K, Molohon KJ, Wang Y, Mitchell DA, Nizet V, et al. HIV-1 Integrase Inhibitor-Inspired Antibacterials Targeting Isoprenoid Biosynthesis. Acs Medicinal Chemistry Letters. 3: 402-406. PMID 22662288 DOI: 10.1021/Ml300038T  0.5
2012 Fair RJ, Hensler ME, Thienphrapa W, Dam QN, Nizet V, Tor Y. Selectively guanidinylated aminoglycosides as antibiotics. Chemmedchem. 7: 1237-44. PMID 22639134 DOI: 10.1002/Cmdc.201200150  0.636
2012 Lin FY, Zhang Y, Hensler M, Liu YL, Chow OA, Zhu W, Wang K, Pang R, Thienphrapa W, Nizet V, Oldfield E. Dual dehydrosqualene/squalene synthase inhibitors: leads for innate immune system-based therapeutics. Chemmedchem. 7: 561-4. PMID 22290830 DOI: 10.1002/Cmdc.201100589  0.784
2012 Sakoulas G, Nam SJ, Loesgen S, Fenical W, Jensen PR, Nizet V, Hensler M. Novel bacterial metabolite merochlorin A demonstrates in vitro activity against multi-drug resistant methicillin-resistant Staphylococcus aureus. Plos One. 7: e29439. PMID 22279537 DOI: 10.1371/Journal.Pone.0029439  0.692
2011 Sun P, Maloney KN, Nam SJ, Haste NM, Raju R, Aalbersberg W, Jensen PR, Nizet V, Hensler ME, Fenical W. Fijimycins A-C, three antibacterial etamycin-class depsipeptides from a marine-derived Streptomyces sp. Bioorganic & Medicinal Chemistry. 19: 6557-62. PMID 21745747 DOI: 10.1016/J.Bmc.2011.06.053  0.752
2011 Haste NM, Farnaes L, Perera VR, Fenical W, Nizet V, Hensler ME. Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus Marine Drugs. 9: 680-689. PMID 21731557 DOI: 10.3390/Md9040680  0.811
2011 Haste NM, Hughes CC, Tran DN, Fenical W, Jensen PR, Nizet V, Hensler ME. Pharmacological properties of the marine natural product marinopyrrole A against methicillin-resistant Staphylococcus aureus. Antimicrobial Agents and Chemotherapy. 55: 3305-12. PMID 21502631 DOI: 10.1128/Aac.01211-10  0.813
2010 Chow OA, von Köckritz-Blickwede M, Bright AT, Hensler ME, Zinkernagel AS, Cogen AL, Gallo RL, Monestier M, Wang Y, Glass CK, Nizet V. Statins enhance formation of phagocyte extracellular traps. Cell Host & Microbe. 8: 445-54. PMID 21075355 DOI: 10.1016/J.Chom.2010.10.005  0.771
2010 Derbal S, Hensler M, Fang W, Nizet V, Ghedira K, Nefzi A. On resin amino acid side chain attachment strategy for the head to tail synthesis of new glutamine containing gramicidin-S analogs and their antimicrobial activity Bioorganic and Medicinal Chemistry Letters. 20: 5701-5704. PMID 20800485 DOI: 10.1016/J.Bmcl.2010.08.015  0.636
2010 Gonzalez DJ, Lee SW, Hensler ME, Markley AL, Dahesh S, Mitchell DA, Bandeira N, Nizet V, Dixon JE, Dorrestein PC. Clostridiolysin S, a post-translationally modified biotoxin from Clostridium botulinum. The Journal of Biological Chemistry. 285: 28220-8. PMID 20581111 DOI: 10.1074/Jbc.M110.118554  0.541
2010 Haste NM, Perera VR, Maloney KN, Tran DN, Jensen P, Fenical W, Nizet V, Hensler ME. Activity of the streptogramin antibiotic etamycin against methicillin-resistant Staphylococcus aureus. The Journal of Antibiotics. 63: 219-24. PMID 20339399 DOI: 10.1038/Ja.2010.22  0.817
2009 Song Y, Liu CI, Lin FY, No JH, Hensler M, Liu YL, Jeng WY, Low J, Liu GY, Nizet V, Wang AH, Oldfield E. Inhibition of staphyloxanthin virulence factor biosynthesis in Staphylococcus aureus: in vitro, in vivo, and crystallographic results. Journal of Medicinal Chemistry. 52: 3869-80. PMID 19456099 DOI: 10.1021/Jm9001764  0.681
2009 Song Y, Lin FY, Yin F, Hensler M, Rodrígues Poveda CA, Mukkamala D, Cao R, Wang H, Morita CT, González Pacanowska D, Nizet V, Oldfield E. Phosphonosulfonates are potent, selective inhibitors of dehydrosqualene synthase and staphyloxanthin biosynthesis in Staphylococcus aureus. Journal of Medicinal Chemistry. 52: 976-88. PMID 19191557 DOI: 10.1021/Jm801023U  0.564
2008 Hensler ME, Miyamoto S, Nizet V. Group B streptococcal beta-hemolysin/cytolysin directly impairs cardiomyocyte viability and function. Plos One. 3: e2446. PMID 18560574 DOI: 10.1371/Journal.Pone.0002446  0.366
2008 Dahesh S, Hensler ME, Van Sorge NM, Gertz RE, Schrag S, Nizet V, Beall BW. Point mutation in the group B streptococcal pbp2x gene conferring decreased susceptibility to beta-lactam antibiotics. Antimicrobial Agents and Chemotherapy. 52: 2915-8. PMID 18541727 DOI: 10.1128/Aac.00461-08  0.698
2008 Lee SW, Mitchell DA, Markley AL, Hensler ME, Gonzalez D, Wohlrab A, Dorrestein PC, Nizet V, Dixon JE. Discovery of a widely distributed toxin biosynthetic gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 105: 5879-84. PMID 18375757 DOI: 10.1073/Pnas.0801338105  0.553
2008 Liu CI, Liu GY, Song Y, Yin F, Hensler ME, Jeng WY, Nizet V, Wang AH, Oldfield E. A cholesterol biosynthesis inhibitor blocks Staphylococcus aureus virulence. Science (New York, N.Y.). 319: 1391-4. PMID 18276850 DOI: 10.1126/Science.1153018  0.708
2008 Maisey HC, Quach D, Hensler ME, Liu GY, Gallo RL, Nizet V, Doran KS. A group B streptococcal pilus protein promotes phagocyte resistance and systemic virulence Faseb Journal. 22: 1715-1724. PMID 18198218 DOI: 10.1096/Fj.07-093963  0.752
2008 Meluzzi D, Zheng WH, Hensler M, Nizet V, Dorrestein PC. Top-down mass spectrometry on low-resolution instruments: characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways. Bioorganic & Medicinal Chemistry Letters. 18: 3107-11. PMID 18006314 DOI: 10.1016/J.Bmcl.2007.10.104  0.425
2008 Hensler ME, Quach D, Hsieh CJ, Doran KS, Nizet V. CAMP factor is not essential for systemic virulence of Group B Streptococcus Microbial Pathogenesis. 44: 84-88. PMID 17870297 DOI: 10.1016/J.Micpath.2007.08.005  0.676
2007 Maisey HC, Hensler M, Nizet V, Doran KS. Group B streptococcal pilus proteins contribute to adherence to and invasion of brain microvascular endothelial cells Journal of Bacteriology. 189: 1464-1467. PMID 17041051 DOI: 10.1128/Jb.01153-06  0.643
2006 Hensler ME, Bernstein G, Nizet V, Nefzi A. Pyrrolidine bis-cyclic guanidines with antimicrobial activity against drug-resistant Gram-positive pathogens identified from a mixture-based combinatorial library. Bioorganic & Medicinal Chemistry Letters. 16: 5073-9. PMID 16890437 DOI: 10.1016/J.Bmcl.2006.07.037  0.627
2006 Lewis AL, Hensler ME, Varki A, Nizet V. The group B streptococcal sialic acid O-acetyltransferase is encoded by neuD, a conserved component of bacterial sialic acid biosynthetic gene clusters. The Journal of Biological Chemistry. 281: 11186-92. PMID 16490781 DOI: 10.1074/Jbc.M513772200  0.619
2006 Maisey HC, Hensler ME, Khosravi A, Liu GY, Nizet V, Doran KS. A single streptococcal gene can confer innate immune resistance and virulence to a nonpathogenic bacterium International Congress Series. 1289: 223-226. DOI: 10.1016/j.ics.2005.10.024  0.702
2005 Hensler ME, Liu GY, Sobczak S, Benirschke K, Nizet V, Heldt GP. Virulence role of group B Streptococcus β-hemolysin/cytolysin in a neonatal rabbit model of early-onset pulmonary infection Journal of Infectious Diseases. 191: 1287-1291. PMID 15776375 DOI: 10.1086/428946  0.59
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