Kyle Loh - Publications

Affiliations: 
Developmental Biology Stanford University School of Medicine, Palo Alto, CA, United States 

43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fowler JL, Zheng SL, Nguyen A, Chen A, Xiong X, Chai T, Chen JY, Karigane D, Banuelos AM, Niizuma K, Kayamori K, Nishimura T, Cromer MK, Gonzalez-Perez D, Mason C, ... ... Loh KM, et al. Lineage-tracing hematopoietic stem cell origins in vivo to efficiently make human HLF+ HOXA+ hematopoietic progenitors from pluripotent stem cells. Developmental Cell. PMID 38569552 DOI: 10.1016/j.devcel.2024.03.003  0.788
2023 Vijayakumar S, Sala R, Kang G, Chen A, Pablo MA, Adebayo AI, Cipriano A, Fowler JL, Gomes DL, Ang LT, Loh KM, Sebastiano V. Monolayer platform to generate and purify primordial germ-like cells in vitro provides insights into human germline specification. Nature Communications. 14: 5690. PMID 37709760 DOI: 10.1038/s41467-023-41302-w  0.842
2023 Loh KM, Ang LT. Building human artery and vein endothelial cells from pluripotent stem cells, and enduring mysteries surrounding arteriovenous development. Seminars in Cell & Developmental Biology. PMID 37393122 DOI: 10.1016/j.semcdb.2023.06.004  0.833
2023 Shah PP, Keough KC, Gjoni K, Santini GT, Abdill RJ, Wickramasinghe NM, Dundes CE, Karnay A, Chen A, Salomon REA, Walsh PJ, Nguyen SC, Whalen S, Joyce EF, Loh KM, et al. An atlas of lamina-associated chromatin across twelve human cell types reveals an intermediate chromatin subtype. Genome Biology. 24: 16. PMID 36691074 DOI: 10.1186/s13059-023-02849-5  0.763
2022 Genuth NR, Shi Z, Kunimoto K, Hung V, Xu AF, Kerr CH, Tiu GC, Oses-Prieto JA, Salomon-Shulman REA, Axelrod JD, Burlingame AL, Loh KM, Barna M. A stem cell roadmap of ribosome heterogeneity reveals a function for RPL10A in mesoderm production. Nature Communications. 13: 5491. PMID 36123354 DOI: 10.1038/s41467-022-33263-3  0.468
2022 Gonzalez-Perez D, Das S, Antfolk D, Ahsan HS, Medina E, Dundes CE, Jokhai RT, Egan ED, Blacklow SC, Loh KM, Rodriguez PC, Luca VC. Affinity-matured DLL4 ligands as broad-spectrum modulators of Notch signaling. Nature Chemical Biology. PMID 36050494 DOI: 10.1038/s41589-022-01113-4  0.747
2022 Roodgar M, Suchy FP, Nguyen LH, Bajpai VK, Sinha R, Vilches-Moure JG, Van Bortle K, Bhadury J, Metwally A, Jiang L, Jian R, Chiang R, Oikonomopoulos A, Wu JC, Weissman IL, ... ... Loh KM, et al. Chimpanzee and pig-tailed macaque iPSCs: Improved culture and generation of primate cross-species embryos. Cell Reports. 40: 111264. PMID 36044843 DOI: 10.1016/j.celrep.2022.111264  0.609
2022 Ang LT, Nguyen AT, Liu KJ, Chen A, Xiong X, Curtis M, Martin RM, Raftry BC, Ng CY, Vogel U, Lander A, Lesch BJ, Fowler JL, Holman AR, Chai T, ... ... Loh KM, et al. Generating human artery and vein cells from pluripotent stem cells highlights the arterial tropism of Nipah and Hendra viruses. Cell. PMID 35738284 DOI: 10.1016/j.cell.2022.05.024  0.771
2021 Raftrey B, Williams IM, Rios Coronado PE, Fan X, Chang AH, Zhao M, Roth RK, Trimm E, Racelis R, D'Amato G, Phansalkar R, Nguyen A, Chai T, Gonzalez KM, Zhang Y, ... ... Loh K, et al. Dach1 Extends Artery Networks and Protects Against Cardiac Injury. Circulation Research. PMID 34383559 DOI: 10.1161/CIRCRESAHA.120.318271  0.747
2020 Roth JG, Muench KL, Asokan A, Mallett VM, Gai H, Verma Y, Weber S, Charlton C, Fowler JL, Loh KM, Dolmetsch RE, Palmer TD. 16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development. Elife. 9. PMID 33169669 DOI: 10.7554/eLife.58178  0.826
2020 Martin RM, Fowler JL, Cromer MK, Lesch BJ, Ponce E, Uchida N, Nishimura T, Porteus MH, Loh KM. Improving the safety of human pluripotent stem cell therapies using genome-edited orthogonal safeguards. Nature Communications. 11: 2713. PMID 32483127 DOI: 10.1038/S41467-020-16455-7  0.825
2020 Dundes CE, Loh KM. Bridging naïve and primed pluripotency. Nature Cell Biology. 22: 513-515. PMID 32367045 DOI: 10.1038/s41556-020-0509-9  0.789
2020 Cui KW, Engel L, Dundes CE, Nguyen TC, Loh KM, Dunn AR. Spatially controlled stem cell differentiation via morphogen gradients: A comparison of static and dynamic microfluidic platforms. Journal of Vacuum Science & Technology. a, Vacuum, Surfaces, and Films : An Official Journal of the American Vacuum Society. 38: 033205. PMID 32255900 DOI: 10.1116/1.5142012  0.847
2019 Fowler JL, Ang LT, Loh KM. A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids. Wiley Interdisciplinary Reviews. Developmental Biology. e368. PMID 31746148 DOI: 10.1002/Wdev.368  0.85
2019 Wilkinson AC, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh KM, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. Author Correction: Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. Nature. PMID 31289376 DOI: 10.1038/S41586-019-1395-9  0.317
2019 Loh KM, Palaria A, Ang LT. Efficient Differentiation of Human Pluripotent Stem Cells into Liver Cells. Journal of Visualized Experiments : Jove. PMID 31259908 DOI: 10.3791/58975  0.82
2019 George BM, Kao KS, Kwon HS, Velasco BJ, Poyser J, Chen A, Le AC, Chhabra A, Burnett CE, Cajuste D, Hoover M, Loh KM, Shizuru JA, Weissman IL. Antibody Conditioning Enables MHC-Mismatched Hematopoietic Stem Cell Transplants and Organ Graft Tolerance. Cell Stem Cell. PMID 31204177 DOI: 10.1016/J.Stem.2019.05.018  0.801
2019 Wilkinson AC, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh KM, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. Long-term ex vivo haematopoietic-stem-cell expansion allows nonconditioned transplantation. Nature. PMID 31142833 DOI: 10.1038/S41586-019-1244-X  0.4
2019 Wilkinson A, Ishida R, Kikuchi M, Sudo K, Morita M, Crisostomo RV, Yamamoto R, Loh K, Nakamura Y, Watanabe M, Nakauchi H, Yamazaki S. 2001 - LONG-TERM EX VIVO EXPANSION OF FUNCTIONAL HEMATOPOIETIC STEM CELLS Experimental Hematology. 76: S42. DOI: 10.1016/J.Exphem.2019.06.276  0.425
2018 Nichane M, Loh KM. Obliterating Obstacles to an Odyssey. Cell Stem Cell. 23: 313-315. PMID 30193127 DOI: 10.1016/J.Stem.2018.08.013  0.827
2018 Ang LT, Tan AKY, Autio MI, Goh SH, Choo SH, Lee KL, Tan J, Pan B, Lee JJH, Lum JJ, Lim CYY, Yeo IKX, Wong CJY, Liu M, Oh JLL, ... ... Loh KM, et al. A Roadmap for Human Liver Differentiation from Pluripotent Stem Cells. Cell Reports. 22: 2190-2205. PMID 29466743 DOI: 10.1016/J.Celrep.2018.01.087  0.821
2017 Nichane M, Javed A, Sivakamasundari V, Ganesan M, Ang LT, Kraus P, Lufkin T, Loh KM, Lim B. Isolation and 3D expansion of multipotent Sox9(+) mouse lung progenitors. Nature Methods. PMID 29106405 DOI: 10.1038/Nmeth.4498  0.818
2017 Tan AKY, Loh KM, Ang LT. Evaluating the regenerative potential and functionality of human liver cells in mice. Differentiation; Research in Biological Diversity. 98: 25-34. PMID 29078082 DOI: 10.1016/J.Diff.2017.09.003  0.786
2017 Brown K, Loh KM, Nusse R. Live Imaging Reveals that the First Division of Differentiating Human Embryonic Stem Cells Often Yields Asymmetric Fates. Cell Reports. 21: 301-307. PMID 29020617 DOI: 10.1016/J.Celrep.2017.09.044  0.52
2016 Koh PW, Sinha R, Barkal AA, Morganti RM, Chen A, Weissman IL, Ang LT, Kundaje A, Loh KM. An atlas of transcriptional, chromatin accessibility, and surface marker changes in human mesoderm development. Scientific Data. 3: 160109. PMID 27996962 DOI: 10.1038/Sdata.2016.109  0.819
2016 Cheng H, Ang HY, A El Farran C, Li P, Fang HT, Liu TM, Kong SL, Chin ML, Ling WY, Lim EK, Li H, Huber T, Loh KM, Loh YH, Lim B. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors. Nature Communications. 7: 13396. PMID 27869129 DOI: 10.1038/Ncomms13396  0.698
2016 Masaki H, Kato-Itoh M, Takahashi Y, Umino A, Sato H, Ito K, Yanagida A, Nishimura T, Yamaguchi T, Hirabayashi M, Era T, Loh KM, Wu SM, Weissman IL, Nakauchi H. Inhibition of Apoptosis Overcomes Stage-Related Compatibility Barriers to Chimera Formation in Mouse Embryos. Cell Stem Cell. 19: 587-592. PMID 27814480 DOI: 10.1016/J.Stem.2016.10.013  0.598
2016 Loh KM, Chen A, Koh PW, Deng TZ, Sinha R, Tsai JM, Barkal AA, Shen KY, Jain R, Morganti RM, Shyh-Chang N, Fernhoff NB, George BM, Wernig G, Salomon RE, et al. Mapping the Pairwise Choices Leading from Pluripotency to Human Bone, Heart, and Other Mesoderm Cell Types. Cell. 166: 451-467. PMID 27419872 DOI: 10.1016/J.Cell.2016.06.011  0.77
2015 Loh KM, Lim B. Stem cells: Equilibrium established. Nature. 521: 299-300. PMID 25993958 DOI: 10.1038/521299A  0.674
2015 Loh KM, Lim B, Ang LT. Ex uno plures: molecular designs for embryonic pluripotency. Physiological Reviews. 95: 245-95. PMID 25540144 DOI: 10.1152/Physrev.00001.2014  0.86
2014 Clevers H, Loh KM, Nusse R. Stem cell signaling. An integral program for tissue renewal and regeneration: Wnt signaling and stem cell control. Science (New York, N.Y.). 346: 1248012. PMID 25278615 DOI: 10.1126/Science.1248012  0.45
2014 Durruthy-Durruthy J, Briggs SF, Awe J, Ramathal CY, Karumbayaram S, Lee PC, Heidmann JD, Clark A, Karakikes I, Loh KM, Wu JC, Hoffman AR, Byrne J, Reijo Pera RA, Sebastiano V. Rapid and efficient conversion of integration-free human induced pluripotent stem cells to GMP-grade culture conditions. Plos One. 9: e94231. PMID 24718618 DOI: 10.1371/Journal.Pone.0094231  0.329
2014 Roberts RM, Loh KM, Amita M, Bernardo AS, Adachi K, Alexenko AP, Schust DJ, Schulz LC, Telugu BP, Ezashi T, Pedersen RA. Differentiation of trophoblast cells from human embryonic stem cells: to be or not to be? Reproduction (Cambridge, England). 147: D1-12. PMID 24518070 DOI: 10.1530/Rep-14-0080  0.521
2014 Loh KM, Ang LT, Zhang J, Kumar V, Ang J, Auyeong JQ, Lee KL, Choo SH, Lim CY, Nichane M, Tan J, Noghabi MS, Azzola L, Ng ES, Durruthy-Durruthy J, et al. Efficient endoderm induction from human pluripotent stem cells by logically directing signals controlling lineage bifurcations. Cell Stem Cell. 14: 237-52. PMID 24412311 DOI: 10.1016/J.Stem.2013.12.007  0.836
2013 Loh KM, Lim B. Stem cells: Close encounters with full potential. Nature. 502: 41-2. PMID 24048472 DOI: 10.1038/Nature12561  0.723
2013 Chan CK, Lindau P, Jiang W, Chen JY, Zhang LF, Chen CC, Seita J, Sahoo D, Kim JB, Lee A, Park S, Nag D, Gong Y, Kulkarni S, Luppen CA, ... ... Loh K, et al. Clonal precursor of bone, cartilage, and hematopoietic niche stromal cells. Proceedings of the National Academy of Sciences of the United States of America. 110: 12643-8. PMID 23858471 DOI: 10.1073/Pnas.1310212110  0.845
2013 Loh KM, Lim B. Rejuvenating tithonus. Embo Reports. 14: 583-4. PMID 23764924 DOI: 10.1038/embor.2013.81  0.509
2012 Cao S, Loh K, Pei Y, Zhang W, Han J. Overcoming barriers to the clinical utilization of iPSCs: Reprogramming efficiency, safety and quality Protein and Cell. 3: 834-845. PMID 23073833 DOI: 10.1007/S13238-012-2078-6  0.552
2012 Loh KM, Lim B. Epigenetics: Actors in the cell reprogramming drama. Nature. 488: 599-600. PMID 22932382 DOI: 10.1038/488599A  0.681
2012 Heng JC, Loh KM, Ng HH. Investigating the bona fide differentiation capacity of human pluripotent stem cells. Cell Research. 22: 6-8. PMID 21876556 DOI: 10.1038/cr.2011.142  0.51
2011 Loh KM, Lim B. A precarious balance: pluripotency factors as lineage specifiers. Cell Stem Cell. 8: 363-9. PMID 21474100 DOI: 10.1016/J.Stem.2011.03.013  0.703
2010 Loh KM, Lim B. Recreating pluripotency? Cell Stem Cell. 7: 137-9. PMID 20682438 DOI: 10.1016/j.stem.2010.07.005  0.636
2009 Ichida JK, Blanchard J, Lam K, Son EY, Chung JE, Egli D, Loh KM, Carter AC, Di Giorgio FP, Koszka K, Huangfu D, Akutsu H, Liu DR, Rubin LL, Eggan K. A small-molecule inhibitor of tgf-Beta signaling replaces sox2 in reprogramming by inducing nanog. Cell Stem Cell. 5: 491-503. PMID 19818703 DOI: 10.1016/J.Stem.2009.09.012  0.629
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