Yann Le Guen - Publications

Affiliations: 
Stanford University School of Medicine, Palo Alto, CA, United States 
Area:
Neurology and Neurological Sciences

0/46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2024 Bhattarai P, Gunasekaran TI, Belloy ME, Reyes-Dumeyer D, Jülich D, Tayran H, Yilmaz E, Flaherty D, Turgutalp B, Sukumar G, Alba C, McGrath EM, Hupalo DN, Bacikova D, Le Guen Y, et al. Rare genetic variation in fibronectin 1 (FN1) protects against APOEε4 in Alzheimer's disease. Acta Neuropathologica. 147: 70. PMID 38598053 DOI: 10.1007/s00401-024-02721-1  0.01
2024 Wilson EN, Wang C, Swarovski MS, Zera KA, Ennerfelt HE, Wang Q, Chaney A, Gauba E, Ramos Benitez JA, Le Guen Y, Minhas PS, Panchal M, Tan YJ, Blacher E, A Iweka C, et al. TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models. Nature Neuroscience. PMID 38539014 DOI: 10.1038/s41593-024-01610-w  0.01
2024 He Z, Chu B, Yang J, Gu J, Chen Z, Liu L, Morrison T, Belloy ME, Qi X, Hejazi N, Mathur M, Le Guen Y, Tang H, Hastie T, Ionita-Laza I, et al. In silico identification of putative causal genetic variants. Biorxiv : the Preprint Server For Biology. PMID 38464202 DOI: 10.1101/2024.02.28.582621  0.01
2024 Chemparathy A, Le Guen Y, Chen S, Lee EG, Leong L, Gorzynski JE, Jensen TD, Ferrasse A, Xu G, Xiang H, Belloy ME, Kasireddy N, Peña-Tauber A, Williams K, Stewart I, et al. APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology. Neuron. PMID 38301647 DOI: 10.1016/j.neuron.2024.01.008  0.01
2024 Wang L, Nykänen NP, Western D, Gorijala P, Timsina J, Li F, Wang Z, Ali M, Yang C, Liu M, Brock W, Marquié M, Boada M, Alvarez I, Aguilar M, ... ... Le Guen Y, et al. Proteo-genomics of soluble TREM2 in cerebrospinal fluid provides novel insights and identifies novel modulators for Alzheimer's disease. Molecular Neurodegeneration. 19: 1. PMID 38172904 DOI: 10.1186/s13024-023-00687-4  0.01
2023 Bharat V, Durairaj AS, Vanhauwaert R, Li L, Muir CM, Chandra S, Kwak CS, Le Guen Y, Nandakishore P, Hsieh CH, Rensi SE, Altman RB, Greicius MD, Feng L, Wang X. A mitochondrial inside-out iron-calcium signal reveals drug targets for Parkinson's disease. Cell Reports. 42: 113544. PMID 38060381 DOI: 10.1016/j.celrep.2023.113544  0.01
2023 Belloy ME, Andrews SJ, Le Guen Y, Cuccaro M, Farrer LA, Napolioni V, Greicius MD. APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry. Jama Neurology. PMID 37930705 DOI: 10.1001/jamaneurol.2023.3599  0.01
2023 Clay CE, Hoover KW, Le Guen Y, Bennett CL. Estimates of HIV testing at Visits to U.S. emergency departments, 2014-2020. Aids (London, England). PMID 37830905 DOI: 10.1097/QAD.0000000000003750  0.01
2023 Graber-Naidich A, Lee J, Younes K, Greicius MD, Le Guen Y, He Z. Loop diuretics association with Alzheimer's disease risk. Frontiers in Aging. 4: 1211571. PMID 37822457 DOI: 10.3389/fragi.2023.1211571  0.01
2023 Gyawali PK, Le Guen Y, Liu X, Belloy ME, Tang H, Zou J, He Z. Improving genetic risk prediction across diverse population by disentangling ancestry representations. Communications Biology. 6: 964. PMID 37736834 DOI: 10.1038/s42003-023-05352-6  0.01
2023 Talyansky S, Le Guen Y, Kasireddy N, Belloy ME, Greicius MD. APOE-ε4 and BIN1 increase risk of Alzheimer's disease pathology but not specifically of Lewy body pathology. Acta Neuropathologica Communications. 11: 149. PMID 37700353 DOI: 10.1186/s40478-023-01626-6  0.01
2023 Le Guen Y, Luo G, Ambati A, Damotte V, Jansen I, Yu E, Nicolas A, de Rojas I, Peixoto Leal T, Miyashita A, Bellenguez C, Lian MM, Parveen K, Morizono T, Park H, et al. Multiancestry analysis of the HLA locus in Alzheimer's and Parkinson's diseases uncovers a shared adaptive immune response mediated by subtypes. Proceedings of the National Academy of Sciences of the United States of America. 120: e2302720120. PMID 37643212 DOI: 10.1073/pnas.2302720120  0.01
2023 Dato S, De Rango F, Crocco P, Pallotti S, Belloy ME, Le Guen Y, Greicius MD, Passarino G, Rose G, Napolioni V. Sex- and APOE-specific genetic risk factors for late-onset Alzheimer's disease: Evidence from gene-gene interaction of longevity-related loci. Aging Cell. e13938. PMID 37621137 DOI: 10.1111/acel.13938  0.01
2023 Bijok B, Jaulin F, Picard J, Michelet D, Fuzier R, Arzalier-Daret S, Basquin C, Blanié A, Chauveau L, Cros J, Delmas V, Dupanloup D, Gauss T, Hamada S, Le Guen Y, et al. Text validated by the Comité des Référentiels Cliniques (clinical guidelines committee) of the SFAR on 14/05/2022, and by the Conseils d'administration (boards of directors) of the SFAR on 19/05/2022 and Groupe Facteurs Humains en Santé (GFHS) on 04/07/2022. Anaesthesia, Critical Care & Pain Medicine. 101262. PMID 37290697 DOI: 10.1016/j.accpm.2023.101262  0.01
2023 Behouche A, Gaide-Chevronnay L, Piot J, Durost M, Adolle A, Le Guen Y, Vilotitch A, Bosson JL, Sebestyen A, Durand M, Albaladejo P. Early extubation in extracorporeal life support patients: A propensity score-matched study. Artificial Organs. PMID 37005770 DOI: 10.1111/aor.14532  0.01
2023 Le Guen Y, Raulin AC, Logue MW, Sherva R, Belloy ME, Eger SJ, Chen A, Kennedy G, Kuchenbecker L, O'Leary JP, Zhang R, Merritt VC, Panizzon MS, Hauger RL, Gaziano JM, et al. Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease. Jama. 329: 551-560. PMID 36809323 DOI: 10.1001/jama.2023.0268  0.01
2023 Remy Q, Hohlfeld J, Vergès M, Le Guen Y, Gorchon J, Malinowski G, Mangin S, Hehn M. Accelerating ultrafast magnetization reversal by non-local spin transfer. Nature Communications. 14: 445. PMID 36707525 DOI: 10.1038/s41467-023-36164-1  0.01
2022 Vergès M, Perumbilavil S, Hohlfeld J, Freire-Fernández F, Le Guen Y, Kuznetsov N, Montaigne F, Malinowski G, Lacour D, Hehn M, van Dijken S, Mangin S. Energy Efficient Single Pulse Switching of [Co/Gd/Pt] Nanodisks Using Surface Lattice Resonances. Advanced Science (Weinheim, Baden-Wurttemberg, Germany). e2204683. PMID 36507620 DOI: 10.1002/advs.202204683  0.01
2022 He Z, Liu L, Belloy ME, Le Guen Y, Sossin A, Liu X, Qi X, Ma S, Gyawali PK, Wyss-Coray T, Tang H, Sabatti C, Candès E, Greicius MD, Ionita-Laza I. GhostKnockoff inference empowers identification of putative causal variants in genome-wide association studies. Nature Communications. 13: 7209. PMID 36418338 DOI: 10.1038/s41467-022-34932-z  0.01
2022 Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N, Norsworthy PJ, Dols-Icardo O, Hummerich H, Kawalia A, Amouyel P, ... ... Le Guen Y, et al. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. Nature Genetics. PMID 36411364 DOI: 10.1038/s41588-022-01208-7  0.01
2022 Wilson EN, Young CB, Ramos Benitez J, Swarovski MS, Feinstein I, Vandijck M, Le Guen Y, Kasireddy NM, Shahid M, Corso NK, Wang Q, Kennedy G, Trelle AN, Lind B, Channappa D, et al. Performance of a fully-automated Lumipulse plasma phospho-tau181 assay for Alzheimer's disease. Alzheimer's Research & Therapy. 14: 172. PMID 36371232 DOI: 10.1186/s13195-022-01116-2  0.01
2022 Belloy ME, Le Guen Y, Eger SJ, Napolioni V, Greicius MD, He Z. A Fast and Robust Strategy to Remove Variant-Level Artifacts in Alzheimer Disease Sequencing Project Data. Neurology. Genetics. 8: e200012. PMID 35966919 DOI: 10.1212/NXG.0000000000200012  0.01
2022 Girardin C, Maze D, Gonçalves C, Le Guen YT, Pluchon K, Pichon C, Montier T, Midoux P. Selective attachment of a microtubule interacting peptide to plasmid DNA via a triplex forming oligonucleotide for transfection improvement. Gene Therapy. PMID 35794469 DOI: 10.1038/s41434-022-00354-1  0.01
2022 Le Guen Y, Belloy ME, Grenier-Boley B, de Rojas I, Castillo-Morales A, Jansen I, Nicolas A, Bellenguez C, Dalmasso C, Küçükali F, Eger SJ, Rasmussen KL, Thomassen JQ, Deleuze JF, He Z, et al. Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease. Jama Neurology. PMID 35639372 DOI: 10.1001/jamaneurol.2022.1166  0.01
2022 Belloy ME, Eger SJ, Le Guen Y, Damotte V, Ahmad S, Ikram MA, Ramirez A, Tsolaki AC, Rossi G, Jansen IE, de Rojas I, Parveen K, Sleegers K, Ingelsson M, Hiltunen M, et al. Challenges at the APOE locus: a robust quality control approach for accurate APOE genotyping. Alzheimer's Research & Therapy. 14: 22. PMID 35120553 DOI: 10.1186/s13195-022-00962-4  0.01
2022 Eger SJ, Le Guen Y, Khan RR, Hall JN, Kennedy G, Zaharchuk G, Couthouis J, Brooks WS, Velakoulis D, Napolioni V, Belloy ME, Dalgard CL, Mormino EC, Gitler AD, Greicius MD. Confirming Pathogenicity of the F386L Variant in a South Asian Family With Early-Onset Alzheimer Disease. Neurology. Genetics. 8: e647. PMID 34901437 DOI: 10.1212/NXG.0000000000000647  0.01
2021 He Z, Le Guen Y, Liu L, Lee J, Ma S, Yang AC, Liu X, Rutledge J, Losada PM, Song B, Belloy ME, Butler RR, Longo FM, Tang H, Mormino EC, et al. Genome-wide analysis of common and rare variants via multiple knockoffs at biobank scale, with an application to Alzheimer disease genetics. American Journal of Human Genetics. 108: 2336-2353. PMID 34767756 DOI: 10.1016/j.ajhg.2021.10.009  0.01
2021 He Z, Liu L, Wang C, Le Guen Y, Lee J, Gogarten S, Lu F, Montgomery S, Tang H, Silverman EK, Cho MH, Greicius M, Ionita-Laza I. Identification of putative causal loci in whole-genome sequencing data via knockoff statistics. Nature Communications. 12: 3152. PMID 34035245 DOI: 10.1038/s41467-021-22889-4  0.01
2021 Le Guen YT, Pichon C, Guégan P, Pluchon K, Haute T, Quemener S, Ropars J, Midoux P, Le Gall T, Montier T. DNA nuclear targeting sequences for enhanced non-viral gene transfer: An and study. Molecular Therapy. Nucleic Acids. 24: 477-486. PMID 33898102 DOI: 10.1016/j.omtn.2021.03.012  0.01
2021 Le Guen Y, Belloy ME, Napolioni V, Eger SJ, Kennedy G, Tao R, He Z, Greicius MD. A novel age-informed approach for genetic association analysis in Alzheimer's disease. Alzheimer's Research & Therapy. 13: 72. PMID 33794991 DOI: 10.1186/s13195-021-00808-5  0.01
2021 Karkar S, Dandine-Roulland C, Mangin JF, Le Guen Y, Philippe C, Deleuze JF, Pierre-Jean M, Le Floch E, Frouin V. Genome-wide haplotype association study in imaging genetics using whole-brain sulcal openings of 16,304 UK Biobank subjects. European Journal of Human Genetics : Ejhg. PMID 33664500 DOI: 10.1038/s41431-021-00827-8  0.01
2021 Belloy ME, Eger SJ, Le Guen Y, Napolioni V, Deters KD, Yang HS, Scelsi MA, Porter T, James SN, Wong A, Schott JM, Sperling RA, Laws SM, Mormino EC, He Z, et al. KL∗VS heterozygosity reduces brain amyloid in asymptomatic at-risk APOE∗4 carriers. Neurobiology of Aging. 101: 123-129. PMID 33610961 DOI: 10.1016/j.neurobiolaging.2021.01.008  0.01
2021 Le Guen Y, Napolioni V, Belloy ME, Yu E, Krohn L, Ruskey JA, Gan-Or Z, Kennedy G, Eger SJ, Greicius MD. Common X-chromosome variants are associated with Parkinson's disease risk. Annals of Neurology. PMID 33583074 DOI: 10.1002/ana.26051  0.01
2020 Hu Z, Benkoulouche M, Barel LA, Le Heiget G, Ben Imeddourene A, Le Guen Y, Monties N, Guerreiro C, Remaud-Siméon M, Moulis C, André I, Mulard LA. A convergent chemoenzymatic strategy to deliver a diversity of serotype-specific O-antigen segments from a unique lightly protected tetrasaccharide core. The Journal of Organic Chemistry. PMID 32700907 DOI: 10.1021/acs.joc.0c00777  0.01
2020 Le Guen Y, Leroy F, Philippe C, Mangin JF, Dehaene-Lambertz G, Frouin V. Enhancer Locus in ch14q23.1 Modulates Brain Asymmetric Temporal Regions Involved in Language Processing. Cerebral Cortex (New York, N.Y. : 1991). PMID 32432689 DOI: 10.1093/cercor/bhaa112  0.01
2020 Belloy ME, Napolioni V, Han SS, Le Guen Y, Greicius MD. Association of Klotho-VS Heterozygosity With Risk of Alzheimer Disease in Individuals Who Carry APOE4. Jama Neurology. PMID 32282020 DOI: 10.1001/Jamaneurol.2020.0414  0.01
2020 Le Guen YT, Le Gall T, Midoux P, Guégan P, Braun S, Montier T. Gene transfer to skeletal muscle using hydrodynamic limb vein injection: current applications, hurdles and possible optimizations. The Journal of Gene Medicine. 22: e3150. PMID 31785130 DOI: 10.1002/jgm.3150  0.01
2019 Mangin JF, Le Guen Y, Labra N, Grigis A, Frouin V, Guevara M, Fischer C, Rivière D, Hopkins WD, Régis J, Sun ZY. "Plis de passage" Deserve a Role in Models of the Cortical Folding Process. Brain Topography. PMID 31583493 DOI: 10.1007/s10548-019-00734-8  0.01
2019 Bouraoui A, Ghanem R, Berchel M, Vié V, Le Guen Y, Paboeuf G, Deschamps L, Le Gall T, Montier T, Jaffrès PA. Bis-Thioether-Containing Lipid Chains in Cationic Amphiphiles: Physicochemical Properties and Applications in Gene Delivery. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 20: 2187-2194. PMID 31393059 DOI: 10.1002/cphc.201900626  0.01
2019 Lubba CH, Le Guen Y, Jarvis S, Jones NS, Cork SC, Eftekhar A, Schultz SR. Correction to: PyPNS: Multiscale Simulation of a Peripheral Nerve in Python. Neuroinformatics. PMID 30993583 DOI: 10.1007/s12021-019-09421-2  0.01
2018 Le Guen Y, Philippe C, Riviere D, Lemaitre H, Grigis A, Fischer C, Dehaene-Lambertz G, Mangin JF, Frouin V. eQTL of KCNK2 regionally influences the brain sulcal widening: evidence from 15,597 UK Biobank participants with neuroimaging data. Brain Structure & Function. PMID 30519892 DOI: 10.1007/s00429-018-1808-9  0.01
2018 Le Guen Y, Amalric M, Pinel P, Pallier C, Frouin V. Shared genetic aetiology between cognitive performance and brain activations in language and math tasks. Scientific Reports. 8: 17624. PMID 30514932 DOI: 10.1038/S41598-018-35665-0  0.01
2018 Le Guen Y, Leroy F, Auzias G, Riviere D, Grigis A, Mangin JF, Coulon O, Dehaene-Lambertz G, Frouin V. The chaotic morphology of the left superior temporal sulcus is genetically constrained. Neuroimage. 174: 297-307. PMID 29571714 DOI: 10.1016/J.Neuroimage.2018.03.046  0.01
2017 Le Guen Y, Auzias G, Leroy F, Noulhiane M, Dehaene-Lambertz G, Duchesnay E, Mangin JF, Coulon O, Frouin V. Genetic Influence on the Sulcal Pits: On the Origin of the First Cortical Folds. Cerebral Cortex (New York, N.Y. : 1991). 1-12. PMID 28444225 DOI: 10.1093/Cercor/Bhx098  0.01
2014 Hargreaves JM, Le Guen Y, Guerreiro C, Descroix K, Mulard LA. Linear synthesis of the branched pentasaccharide repeats of O-antigens from Shigella flexneri 1a and 1b demonstrating the major steric hindrance associated with type-specific glucosylation. Organic & Biomolecular Chemistry. 12: 7728-49. PMID 25141906 DOI: 10.1039/c4ob01200c  0.01
2013 Magrez M, Le Guen Y, Baslé O, Crévisy C, Mauduit M. Bidentate hydroxyalkyl NHC ligands for the copper-catalyzed asymmetric allylic substitution of allyl phosphates with Grignard reagents. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 1199-203. PMID 23255196 DOI: 10.1002/chem.201203969  0.01
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