Kurtis J Swartz - Publications

University of California, San Francisco, San Francisco, CA 
Bird Song, Computational Neuroscience

60 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Huffer KE, Aleksandrova AA, Jara-Oseguera A, Forrest LR, Swartz KJ. Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms. Elife. 9. PMID 32804077 DOI: 10.7554/Elife.58660  0.306
2019 Li M, Wang Y, Banerjee R, Marinelli F, Silberberg S, Faraldo-Gómez JD, Hattori M, Swartz KJ. Molecular mechanisms of human P2X3 receptor channel activation and modulation by divalent cation bound ATP. Elife. 8. PMID 31232692 DOI: 10.7554/Elife.47060  0.306
2019 Zhang F, Swartz KJ, Jara-Oseguera A. Conserved allosteric pathways for activation of TRPV3 revealed through engineering vanilloid-sensitivity. Elife. 8. PMID 30644819 DOI: 10.1016/J.Bpj.2018.11.2881  0.314
2018 Matthies D, Bae C, Toombes GE, Fox T, Bartesaghi A, Subramaniam S, Swartz KJ. Single-particle cryo-EM structure of a voltage-activated potassium channel in lipid nanodiscs. Elife. 7. PMID 30109985 DOI: 10.7554/Elife.37558  0.308
2018 Ballesteros A, Fenollar-Ferrer C, Swartz KJ. Structural relationship between the putative hair cell mechanotransduction channel TMC1 and TMEM16 proteins. Elife. 7. PMID 30063209 DOI: 10.7554/Elife.38433  0.319
2017 Zhang F, Jara-Oseguera A, Chang TH, Bae C, Hanson SM, Swartz KJ. Heat activation is intrinsic to the pore domain of TRPV1. Proceedings of the National Academy of Sciences of the United States of America. PMID 29279388 DOI: 10.1073/Pnas.1717192115  0.321
2017 Hattori D, Aso Y, Swartz KJ, Rubin GM, Abbott LF, Axel R. Representations of Novelty and Familiarity in a Mushroom Body Compartment. Cell. PMID 28502772 DOI: 10.1016/J.Cell.2017.04.028  0.352
2017 Jara-Oseguera A, Swartz KJ. Investigating the Putative Activation Gate in the Selectivity Filter of the TRPV1 Channel Biophysical Journal. 112: 114. DOI: 10.1016/J.Bpj.2016.11.645  0.352
2017 Zhang F, Hanson S, Andres Jara-Oseguera A, Swartz K. Localization of the Temperature Sensors to the Pore Domain of the TRPV1 Channel Biophysical Journal. 112: 114a. DOI: 10.1016/J.Bpj.2016.11.643  0.318
2017 Gupta K, Swartz KJ. Using Unnatural Amino Acids to Probe the Interaction between Tarantula Toxins and Voltage Sensing Domains in KV Channels Biophysical Journal. 112. DOI: 10.1016/J.Bpj.2016.11.1343  0.337
2016 Toombes GE, Swartz KJ. STRUCTURAL BIOLOGY. Twists and turns in gating ion channels with voltage. Science (New York, N.Y.). 353: 646-7. PMID 27516583 DOI: 10.1126/Science.Aah4194  0.315
2016 Jara-Oseguera A, Bae C, Swartz KJ. An external sodium ion binding site controls allosteric gating in TRPV1 channels. Elife. 5. PMID 26882503 DOI: 10.7554/Elife.13356  0.328
2016 Bae C, Anselmi C, Kalia J, Jara-Oseguera A, Schwieters CD, Krepkiy D, Won Lee C, Kim EH, Kim JI, Faraldo-Gómez JD, Swartz KJ. Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin. Elife. 5. PMID 26880553 DOI: 10.7554/Elife.11273  0.34
2016 Bae C, Anselmi C, Kalia J, Jara-Oseguera A, Schwieters CD, Krepkiy D, Won Lee C, Il Kim J, Faraldo-Gómez JD, Swartz KJ. Structure of a Double-Knot Tarantula Toxin Bound to the TRPV1 Channel at the Protein-Lipid Interface Biophysical Journal. 110: 285a. DOI: 10.1016/J.Bpj.2015.11.1544  0.311
2016 Jara-Oseguera A, Bae C, Swartz KJ. Extracellular Sodium is Required for Temperature-Dependent Gating in TRPV1 Channels Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.1538  0.329
2015 Bae C, Anselmi C, Kalia J, Jara-Oseguera A, Schwieters CD, Krepkiy D, Lee CW, Kim E, Kim JI, Faraldo-Gómez JD, Swartz KJ. Author response: Structural insights into the mechanism of activation of the TRPV1 channel by a membrane-bound tarantula toxin Elife. DOI: 10.7554/Elife.11273.028  0.309
2015 Jara-Oseguera A, Swartz KJ. Unraveling Allosteric Coupling Mechanisms in the TRPV1 Channel Biophysical Journal. 108: 124a. DOI: 10.1016/J.Bpj.2014.11.695  0.358
2015 Bae C, Jara-Oseguera A, Krepkiy DV, Ryu J, Kim JI, Swartz KJ. Surface Characterization and Membrane Interaction of Double-Knot Toxin, an Activator of TRPV1 Channels Biophysical Journal. 108: 36a. DOI: 10.1016/J.Bpj.2014.11.227  0.325
2014 Li M, Harnish E, Silberberg SD, Swartz KJ. Subtype-Specific Control of P2X Receptor Signaling by ATP and Magnesium Biophysical Journal. 106: 153a. DOI: 10.1016/J.Bpj.2013.11.881  0.302
2014 Jara-Oseguera A, Bae C, Zhang F, Chang T, Kim JI, Swartz KJ. Exploring the Architecture of the Outer Pore of the TRPV1 Channel with Double-Knot Toxin Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.4157  0.364
2014 Zamanian M, Bae C, Tilley D, Gupta K, Sack J, Yarov-Yarovoy V, Kim JI, Swartz K. Common Interaction Surfaces for Tarantula Toxins Targeting Kv and ASIC Channels Biophysical Journal. 106: 737-738. DOI: 10.1016/J.Bpj.2013.11.4065  0.304
2014 Zhang F, Krepkiy D, Bae C, Moiseenkova-Bell V, Hanson S, Gorshkova I, Pearce L, Blumberg PM, Kim JI, Swartz KJ. Lipid-Mediated Interaction of Double-Knot Toxin with TRPV1 Channels Biophysical Journal. 106: 336a. DOI: 10.1016/J.Bpj.2013.11.1923  0.304
2013 Li M, Silberberg SD, Swartz KJ. Subtype-specific control of P2X receptor channel signaling by ATP and Mg2+. Proceedings of the National Academy of Sciences of the United States of America. 110: E3455-63. PMID 23959888 DOI: 10.1073/Pnas.1308088110  0.316
2013 Kalia J, Swartz KJ. Exploring structure-function relationships between TRP and Kv channels. Scientific Reports. 3: 1523. PMID 23519328 DOI: 10.1038/Srep01523  0.349
2013 Milescu M, Lee HC, Bae CH, Kim JI, Swartz KJ. Opening the shaker K+ channel with hanatoxin. The Journal of General Physiology. 141: 203-16. PMID 23359283 DOI: 10.1085/Jgp.201210914  0.365
2013 Kalia J, Swartz KJ. Common principles of voltage-dependent gating for Hv and Kv channels. Neuron. 77: 214-6. PMID 23352157 DOI: 10.1016/J.Neuron.2013.01.001  0.301
2013 Milescu M, Lee H, Bae CH, Kim JI, Swartz K. Opening the Shaker Kv Channel with Hanatoxin Biophysical Journal. 104: 1-4. DOI: 10.1016/J.Bpj.2012.11.713  0.357
2013 Zamanian M, Bae CH, Kim JI, Swartz K. Defining the Interactive Surfaces of Tarantula Toxins for Voltage Sensors in Kv Channels Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.712  0.309
2012 Kalia J, Swartz KJ. Mechanism of Inhibition of Voltage-Gated Potassium Channels by Guanidine Compounds Biophysical Journal. 102: 533a. DOI: 10.1016/J.Bpj.2011.11.2913  0.307
2012 Ladt KC, Bae C, Yu J, Kim JI, Swartz K. Activation of TRPV1 by a Recombinant Double-Knot Toxin from a Chinese Bird Spider Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.1872  0.339
2011 Kalia J, Swartz KJ. Elucidating the molecular basis of action of a classic drug: guanidine compounds as inhibitors of voltage-gated potassium channels. Molecular Pharmacology. 80: 1085-95. PMID 21926190 DOI: 10.1124/Mol.111.074989  0.304
2011 Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ. Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors. The Journal of General Physiology. 138: 59-72. PMID 21670206 DOI: 10.1085/Jgp.201110614  0.344
2011 Bosmans F, Milescu M, Swartz KJ. Palmitoylation Affects the Interaction of Animal Toxins with Sodium Channels Biophysical Journal. 100: 422a. DOI: 10.1016/J.Bpj.2010.12.2497  0.332
2010 Li M, Kawate T, Silberberg SD, Swartz KJ. Pore-opening mechanism in trimeric P2X receptor channels. Nature Communications. 1: 44. PMID 20975702 DOI: 10.1038/Ncomms1048  0.329
2010 Lee S, Milescu M, Jung HH, Lee JY, Bae CH, Lee CW, Kim HH, Swartz KJ, Kim JI. Solution structure of GxTX-1E, a high-affinity tarantula toxin interacting with voltage sensors in Kv2.1 potassium channels . Biochemistry. 49: 5134-42. PMID 20509680 DOI: 10.1021/Bi100246U  0.344
2010 Bosmans F, Swartz KJ. Targeting voltage sensors in sodium channels with spider toxins. Trends in Pharmacological Sciences. 31: 175-82. PMID 20097434 DOI: 10.1016/J.Tips.2009.12.007  0.316
2010 Kalia J, Swartz KJ. Exploring Structural Relationships between TRP and Kv Channels Biophysical Journal. 98: 341a. DOI: 10.1016/J.Bpj.2009.12.1847  0.351
2009 Silberberg SD, Swartz KJ. Structural biology: Trimeric ion-channel design. Nature. 460: 580-1. PMID 19641581 DOI: 10.1038/460580A  0.309
2009 Bosmans F, Martin-Eauclaire M, Swartz KJ. Using Potassium Channels As Reporters To Deconstruct The Function And Pharmacology Of Sodium Channel Voltage Sensors Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.961  0.338
2009 Milescu M, Swartz KJ. Voltage-sensor Pharmacology Of Voltage-activated Calcium Channels (cav) Biophysical Journal. 96: 184a. DOI: 10.1016/J.Bpj.2008.12.862  0.33
2008 Bosmans F, Martin-Eauclaire MF, Swartz KJ. Deconstructing voltage sensor function and pharmacology in sodium channels. Nature. 456: 202-8. PMID 19005548 DOI: 10.1038/Nature07473  0.301
2008 Li M, Chang TH, Silberberg SD, Swartz KJ. Gating the pore of P2X receptor channels. Nature Neuroscience. 11: 883-7. PMID 18587390 DOI: 10.1038/Nn.2151  0.327
2007 Swartz KJ. Tarantula toxins interacting with voltage sensors in potassium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 213-30. PMID 17097703 DOI: 10.1016/J.Toxicon.2006.09.024  0.362
2006 Swartz KJ. Greasing the gears of potassium channels. Nature Chemical Biology. 2: 401-2. PMID 16850015 DOI: 10.1038/Nchembio0806-401  0.343
2005 Kitaguchi T, Swartz KJ. An inhibitor of TRPV1 channels isolated from funnel Web spider venom. Biochemistry. 44: 15544-9. PMID 16300403 DOI: 10.1021/Bi051494L  0.341
2005 Jung HJ, Lee JY, Kim SH, Eu YJ, Shin SY, Milescu M, Swartz KJ, Kim JI. Solution structure and lipid membrane partitioning of VSTx1, an inhibitor of the KvAP potassium channel. Biochemistry. 44: 6015-23. PMID 15835890 DOI: 10.1021/Bi0477034  0.323
2005 Silberberg SD, Chang TH, Swartz KJ. Secondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels. The Journal of General Physiology. 125: 347-59. PMID 15795310 DOI: 10.1085/Jgp.200409221  0.304
2004 Swartz KJ. Towards a structural view of gating in potassium channels. Nature Reviews. Neuroscience. 5: 905-16. PMID 15550946 DOI: 10.1038/Nrn1559  0.345
2004 Kitaguchi T, Sukhareva M, Swartz KJ. Stabilizing the closed S6 gate in the Shaker Kv channel through modification of a hydrophobic seal. The Journal of General Physiology. 124: 319-32. PMID 15365093 DOI: 10.1085/Jgp.200409098  0.32
2004 Swartz KJ. Opening the gate in potassium channels. Nature Structural & Molecular Biology. 11: 499-501. PMID 15164005 DOI: 10.1038/Nsmb0604-499  0.326
2004 Lee CW, Kim S, Roh SH, Endoh H, Kodera Y, Maeda T, Kohno T, Wang JM, Swartz KJ, Kim JI. Solution structure and functional characterization of SGTx1, a modifier of Kv2.1 channel gating. Biochemistry. 43: 890-7. PMID 14744131 DOI: 10.1021/Bi0353373  0.337
2003 Lee HC, Wang JM, Swartz KJ. Interaction between extracellular Hanatoxin and the resting conformation of the voltage-sensor paddle in Kv channels. Neuron. 40: 527-36. PMID 14642277 DOI: 10.1016/S0896-6273(03)00636-6  0.324
2003 Sukhareva M, Hackos DH, Swartz KJ. Constitutive activation of the Shaker Kv channel. The Journal of General Physiology. 122: 541-56. PMID 14557403 DOI: 10.1085/Jgp.200308905  0.35
2002 Hackos DH, Chang TH, Swartz KJ. Scanning the intracellular S6 activation gate in the shaker K+ channel. The Journal of General Physiology. 119: 521-32. PMID 12034760 DOI: 10.1085/Jgp.20028569  0.323
2001 Li-Smerin Y, Swartz KJ. Helical structure of the COOH terminus of S3 and its contribution to the gating modifier toxin receptor in voltage-gated ion channels. The Journal of General Physiology. 117: 205-18. PMID 11222625 DOI: 10.1085/Jgp.117.3.205  0.318
2000 Winterfield JR, Swartz KJ. A hot spot for the interaction of gating modifier toxins with voltage-dependent ion channels. The Journal of General Physiology. 116: 637-44. PMID 11055992 DOI: 10.1085/Jgp.116.5.637  0.341
2000 Li-Smerin Y, Swartz KJ. Localization and molecular determinants of the Hanatoxin receptors on the voltage-sensing domains of a K(+) channel. The Journal of General Physiology. 115: 673-84. PMID 10828242 DOI: 10.1085/Jgp.115.6.673  0.323
2000 Takahashi H, Kim JI, Min HJ, Sato K, Swartz KJ, Shimada I. Solution structure of hanatoxin1, a gating modifier of voltage-dependent K(+) channels: common surface features of gating modifier toxins. Journal of Molecular Biology. 297: 771-80. PMID 10731427 DOI: 10.1006/Jmbi.2000.3609  0.324
1998 Li-Smerin Y, Swartz KJ. Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca2+ and K+ channels. Proceedings of the National Academy of Sciences of the United States of America. 95: 8585-9. PMID 9671721 DOI: 10.1073/Pnas.95.15.8585  0.325
1997 Swartz KJ, MacKinnon R. Hanatoxin modifies the gating of a voltage-dependent K+ channel through multiple binding sites. Neuron. 18: 665-73. PMID 9136774 DOI: 10.1016/S0896-6273(00)80306-2  0.312
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