| Year |
Citation |
Score |
| 2024 |
Collaço RC, Van Petegem F, Bosmans F. ω-Grammotoxin-SIA inhibits voltage-gated Na+ channel currents. The Journal of General Physiology. 156. PMID 39042091 DOI: 10.1085/jgp.202413563 |
0.606 |
|
| 2023 |
Lopez L, De Waard S, Meudal H, Caumes C, Khakh K, Peigneur S, Oliveira-Mendes B, Lin S, De Waele J, Montnach J, Cestèle S, Tessier A, Johnson JP, Mantegazza M, Tytgat J, ... ... Bosmans F, et al. Structure-function relationship of new peptides activating human Na1.1. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 165: 115173. PMID 37453200 DOI: 10.1016/j.biopha.2023.115173 |
0.474 |
|
| 2023 |
Brackx W, Collaço RC, Theys M, Vander Cruyssen J, Bosmans F. Understanding the physiological role of Na1.9: Challenges and opportunities for pain modulation. Pharmacology & Therapeutics. 245: 108416. PMID 37061202 DOI: 10.1016/j.pharmthera.2023.108416 |
0.312 |
|
| 2022 |
Montnach J, Blömer LA, Lopez L, Filipis L, Meudal H, Lafoux A, Nicolas S, Chu D, Caumes C, Béroud R, Jopling C, Bosmans F, Huchet C, Landon C, Canepari M, et al. In vivo spatiotemporal control of voltage-gated ion channels by using photoactivatable peptidic toxins. Nature Communications. 13: 417. PMID 35058427 DOI: 10.1038/s41467-022-27974-w |
0.509 |
|
| 2021 |
Dobson JS, Harris RJ, Zdenek CN, Huynh T, Hodgson WC, Bosmans F, Fourmy R, Violette A, Fry BG. The Dragon's Paralysing Spell: Evidence of Sodium and Calcium Ion Channel Binding Neurotoxins in Helodermatid and Varanid Lizard Venoms. Toxins. 13. PMID 34437420 DOI: 10.3390/toxins13080549 |
0.425 |
|
| 2021 |
Fraser SP, Onkal R, Theys M, Bosmans F, Djamgoz MBA. Neonatal Na 1.5: Pharmacological distinctiveness of a cancer-related voltage-gated sodium channel splice variant. British Journal of Pharmacology. PMID 34411279 DOI: 10.1111/bph.15668 |
0.46 |
|
| 2021 |
Scala M, Efthymiou S, Sultan T, De Waele J, Panciroli M, Salpietro V, Maroofian R, Striano P, Van Petegem F, Houlden H, Bosmans F. Homozygous SCN1B variants causing early infantile epileptic encephalopathy 52 affect voltage-gated sodium channel function. Epilepsia. PMID 33901312 DOI: 10.1111/epi.16913 |
0.31 |
|
| 2020 |
Llongueras JP, Das S, De Waele J, Capulzini L, Sorgente A, Van Petegem F, Bosmans F. Biophysical Investigation of Sodium Channel Interaction with β-Subunit Variants Associated with Arrhythmias. Bioelectricity. 2: 269-278. PMID 34476357 DOI: 10.1089/bioe.2020.0030 |
0.503 |
|
| 2020 |
Herzig V, Sunagar K, Wilson DTR, Pineda SS, Israel MR, Dutertre S, McFarland BS, Undheim EAB, Hodgson WC, Alewood PF, Lewis RJ, Bosmans F, Vetter I, King GF, Fry BG. Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958636 DOI: 10.1073/Pnas.2004516117 |
0.4 |
|
| 2020 |
Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF. Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target Na1.7. Biochemical Pharmacology. 114080. PMID 32511987 DOI: 10.1016/J.Bcp.2020.114080 |
0.498 |
|
| 2019 |
Nicolas S, Zoukimian C, Bosmans F, Montnach J, Diochot S, Cuypers E, De Waard S, Béroud R, Mebs D, Craik D, Boturyn D, Lazdunski M, Tytgat J, De Waard M. Chemical Synthesis, Proper Folding, Na Channel Selectivity Profile and Analgesic Properties of the Spider Peptide Phlotoxin 1. Toxins. 11. PMID 31234412 DOI: 10.3390/Toxins11060367 |
0.515 |
|
| 2019 |
Clairfeuille T, Cloake A, Infield DT, Llongueras JP, Arthur CP, Li ZR, Jian Y, Martin-Eauclaire MF, Bougis PE, Ciferri C, Ahern CA, Bosmans F, Hackos DH, Rohou A, Payandeh J. Structural basis of α-scorpion toxin action on Nav channels. Science (New York, N.Y.). PMID 30733386 DOI: 10.1126/Science.Aav8573 |
0.78 |
|
| 2018 |
Salvatierra J, Diaz-Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. A disease mutation reveals a role for NaV1.9 in acute itch. The Journal of Clinical Investigation. PMID 30395542 DOI: 10.1172/Jci122481 |
0.483 |
|
| 2018 |
Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, ... Bosmans F, et al. NaV1.1 inhibition can reduce visceral hypersensitivity. Jci Insight. 3. PMID 29875317 DOI: 10.1172/Jci.Insight.121000 |
0.415 |
|
| 2018 |
Männikkö R, Shenkarev ZO, Thor MG, Berkut AA, Myshkin MY, Paramonov AS, Kulbatskii DS, Kuzmin DA, Sampedro Castañeda M, King L, Wilson ER, Lyukmanova EN, Kirpichnikov MP, Schorge S, Bosmans F, et al. Spider toxin inhibits gating pore currents underlying periodic paralysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29636418 DOI: 10.1073/Pnas.1720185115 |
0.617 |
|
| 2017 |
Gilchrist J, Bosmans F. Using voltage-sensor toxins and their molecular targets to investigate NaV 1.8 gating. The Journal of Physiology. PMID 29193176 DOI: 10.1113/Jp275102 |
0.655 |
|
| 2017 |
Osteen JD, Sampson K, Iyer V, Julius D, Bosmans F. Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607094 DOI: 10.1073/Pnas.1621263114 |
0.614 |
|
| 2017 |
Smith JJ, Herzig V, Ikonomopoulou MP, Dziemborowicz S, Bosmans F, Nicholson GM, King GF. Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouri. Toxins. 9. PMID 28475112 DOI: 10.3390/Toxins9050155 |
0.542 |
|
| 2017 |
Klein AH, Vyshnevska A, Hartke TV, De Col R, Mankowski JL, Turnquist BP, Bosmans F, Reeh PW, Schmelz M, Carr RW, Ringkamp M. Sodium channel NaV1.8 underlies TTX-resistant axonal action potential conduction in somatosensory C-fibers of distal cutaneous nerves. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28450535 DOI: 10.1523/Jneurosci.3799-16.2017 |
0.408 |
|
| 2017 |
Wingerd JS, Mozar CA, Ussing CA, Murali SS, Chin YK, Cristofori-Armstrong B, Durek T, Gilchrist J, Vaughan CW, Bosmans F, Adams DJ, Lewis RJ, Alewood PF, Mobli M, Christie MJ, et al. The tarantula toxin β/δ-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity. Scientific Reports. 7: 974. PMID 28428547 DOI: 10.1038/S41598-017-01129-0 |
0.607 |
|
| 2017 |
Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/Srep40883 |
0.382 |
|
| 2016 |
Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon : Official Journal of the International Society On Toxinology. PMID 27793656 DOI: 10.1016/J.Toxicon.2016.10.013 |
0.388 |
|
| 2016 |
Martin-Eauclaire MF, Salvatierra J, Bosmans F, Bougis PE. The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension. Febs Letters. 590: 3221-32. PMID 27528512 DOI: 10.1002/1873-3468.12357 |
0.391 |
|
| 2016 |
Herzig V, Ikonomopoulou M, Smith JJ, Dziemborowicz S, Gilchrist J, Kuhn-Nentwig L, Rezende FO, Moreira LA, Nicholson GM, Bosmans F, King GF. Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami. Scientific Reports. 6: 29538. PMID 27383378 DOI: 10.1038/Srep29538 |
0.602 |
|
| 2016 |
Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, ... ... Bosmans F, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/Nature17976 |
0.48 |
|
| 2016 |
Kwon S, Bosmans F, Kaas Q, Cheneval O, Conibear AC, Rosengren KJ, Wang CK, Schroeder CI, Craik DJ. Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering. PMID 27093300 DOI: 10.1002/Bit.25993 |
0.407 |
|
| 2016 |
Das S, Gilchrist J, Bosmans F, Van Petegem F. Binary architecture of the Nav1.2-β2 signaling complex. Elife. 5. PMID 26894959 DOI: 10.7554/eLife.10960 |
0.448 |
|
| 2016 |
Ahern CA, Payandeh J, Bosmans F, Chanda B. The hitchhiker's guide to the voltage-gated sodium channel galaxy. The Journal of General Physiology. 147: 1-24. PMID 26712848 DOI: 10.1085/Jgp.201511492 |
0.657 |
|
| 2016 |
Das S, Gilchrist J, Bosmans F, Petegem FV. Structural Comparisons of Immunoglobulin Folds of Human Navβ Subunits Biophysical Journal. 110. DOI: 10.1016/J.Bpj.2015.11.643 |
0.385 |
|
| 2015 |
Camargos TS, Bosmans F, Rego SC, Mourão CB, Schwartz EF. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening. Plos One. 10: e0128578. PMID 26083731 DOI: 10.1371/Journal.Pone.0128578 |
0.622 |
|
| 2015 |
Klint JK, Smith JJ, Vetter I, Rupasinghe DB, Er SY, Senff S, Herzig V, Mobli M, Lewis RJ, Bosmans F, King GF. Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology. 172: 2445-58. PMID 25754331 DOI: 10.1111/Bph.13081 |
0.499 |
|
| 2015 |
Martin-Eauclaire MF, Ferracci G, Bosmans F, Bougis PE. A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif. The Journal of General Physiology. 145: 155-62. PMID 25624450 DOI: 10.1085/Jgp.201411268 |
0.566 |
|
| 2015 |
Bende NS, Dziemborowicz S, Herzig V, Ramanujam V, Brown GW, Bosmans F, Nicholson GM, King GF, Mobli M. The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop. The Febs Journal. 282: 904-20. PMID 25559770 DOI: 10.1111/Febs.13189 |
0.517 |
|
| 2015 |
Kalia J, Milescu M, Salvatierra J, Wagner J, Klint JK, King GF, Olivera BM, Bosmans F. From foe to friend: using animal toxins to investigate ion channel function. Journal of Molecular Biology. 427: 158-75. PMID 25088688 DOI: 10.1016/J.Jmb.2014.07.027 |
0.777 |
|
| 2014 |
Bende NS, Dziemborowicz S, Mobli M, Herzig V, Gilchrist J, Wagner J, Nicholson GM, King GF, Bosmans F. A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nature Communications. 5: 4350. PMID 25014760 DOI: 10.1038/Ncomms5350 |
0.638 |
|
| 2014 |
Gilchrist J, Olivera BM, Bosmans F. Animal toxins influence voltage-gated sodium channel function. Handbook of Experimental Pharmacology. 221: 203-29. PMID 24737238 DOI: 10.1007/978-3-642-41588-3_10 |
0.628 |
|
| 2014 |
Gilchrist J, Dutton S, Diaz-Bustamante M, McPherson A, Olivares N, Kalia J, Escayg A, Bosmans F. Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents. Acs Chemical Biology. 9: 1204-12. PMID 24635129 DOI: 10.1021/Cb500108P |
0.736 |
|
| 2014 |
Martin-Eauclaire MF, Bosmans F, Céard B, Diochot S, Bougis PE. A first exploration of the venom of the Buthus occitanus scorpion found in southern France. Toxicon : Official Journal of the International Society On Toxinology. 79: 55-63. PMID 24418174 DOI: 10.1016/J.Toxicon.2014.01.002 |
0.354 |
|
| 2014 |
Das S, Gilchrist J, Bosmans F, Petegem FV. Crystal Structure of the Navβ4 Extracellular Domain Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.278 |
0.47 |
|
| 2014 |
Gilchrist JM, Das S, Petegemn FV, Bosmans F. β4 Modulates NaV1.2 Toxin Pharmacology Biophysical Journal. 106. DOI: 10.1016/J.Bpj.2013.11.276 |
0.481 |
|
| 2013 |
Gilchrist J, Das S, Van Petegem F, Bosmans F. Crystallographic insights into sodium-channel modulation by the β4 subunit. Proceedings of the National Academy of Sciences of the United States of America. 110: E5016-24. PMID 24297919 DOI: 10.1073/Pnas.1314557110 |
0.465 |
|
| 2013 |
Bende NS, Kang E, Herzig V, Bosmans F, Nicholson GM, Mobli M, King GF. The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels. Biochemical Pharmacology. 85: 1542-54. PMID 23473802 DOI: 10.1016/J.Bcp.2013.02.030 |
0.633 |
|
| 2013 |
Gilchrist J, Bosmans F. Rufinamide Modifies the Gating Process of Human Voltage-Gated Sodium Channels Biophysical Journal. 104. DOI: 10.1016/J.Bpj.2012.11.767 |
0.488 |
|
| 2012 |
Gilchrist J, Bosmans F. Animal toxins can alter the function of Nav1.8 and Nav1.9. Toxins. 4: 620-32. PMID 23012651 DOI: 10.3390/Toxins4080620 |
0.536 |
|
| 2012 |
Bosmans F, Swartz KJ. Sodium Channel Voltage Sensor Movements Are Influenced by the Auxiliary β1 Subunit Biophysical Journal. 102. DOI: 10.1016/J.Bpj.2011.11.1789 |
0.69 |
|
| 2011 |
Bosmans F, Milescu M, Swartz KJ. Palmitoylation influences the function and pharmacology of sodium channels. Proceedings of the National Academy of Sciences of the United States of America. 108: 20213-8. PMID 22123950 DOI: 10.1073/Pnas.1108497108 |
0.776 |
|
| 2011 |
Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ. Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors. The Journal of General Physiology. 138: 59-72. PMID 21670206 DOI: 10.1085/Jgp.201110614 |
0.81 |
|
| 2011 |
Bosmans F, Milescu M, Swartz KJ. Palmitoylation Affects the Interaction of Animal Toxins with Sodium Channels Biophysical Journal. 100: 422a. DOI: 10.1016/J.Bpj.2010.12.2497 |
0.822 |
|
| 2010 |
Bosmans F, Swartz KJ. Targeting voltage sensors in sodium channels with spider toxins. Trends in Pharmacological Sciences. 31: 175-82. PMID 20097434 DOI: 10.1016/J.Tips.2009.12.007 |
0.773 |
|
| 2010 |
Bosmans F, Puopolo M, Martin-Eauclaire M, Bean BP, Swartz KJ. Defining the Voltage Sensor Properties and Pharmacology of Nav1.9 Biophysical Journal. 98: 115a. DOI: 10.1016/J.Bpj.2009.12.4215 |
0.777 |
|
| 2009 |
Milescu M, Bosmans F, Lee S, Alabi AA, Kim JI, Swartz KJ. Interactions between lipids and voltage sensor paddles detected with tarantula toxins. Nature Structural & Molecular Biology. 16: 1080-5. PMID 19783984 DOI: 10.1038/Nsmb.1679 |
0.788 |
|
| 2009 |
Corzo G, Bernard C, Clement H, Villegas E, Bosmans F, Tytgat J, Possani LD, Darbon H, Alagón A. Insecticidal peptides from the theraposid spider Brachypelma albiceps: an NMR-based model of Ba2. Biochimica Et Biophysica Acta. 1794: 1190-6. PMID 19374957 DOI: 10.1016/J.Bbapap.2009.04.004 |
0.366 |
|
| 2009 |
Bosmans F, Martin-Eauclaire M, Swartz KJ. Using Potassium Channels As Reporters To Deconstruct The Function And Pharmacology Of Sodium Channel Voltage Sensors Biophysical Journal. 96. DOI: 10.1016/J.Bpj.2008.12.961 |
0.784 |
|
| 2008 |
Bosmans F, Martin-Eauclaire MF, Swartz KJ. Deconstructing voltage sensor function and pharmacology in sodium channels. Nature. 456: 202-8. PMID 19005548 DOI: 10.1038/Nature07473 |
0.76 |
|
| 2008 |
Billen B, Bosmans F, Tytgat J. Animal peptides targeting voltage-activated sodium channels. Current Pharmaceutical Design. 14: 2492-502. PMID 18781997 DOI: 10.2174/138161208785777423 |
0.541 |
|
| 2008 |
Villegas E, Adachi-Akahane S, Bosmans F, Tytgat J, Nakajima T, Corzo G. Biochemical characterization of cysteine-rich peptides from Oxyopes sp. venom that block calcium ion channels. Toxicon : Official Journal of the International Society On Toxinology. 52: 228-36. PMID 18606178 DOI: 10.1016/J.Toxicon.2008.05.019 |
0.44 |
|
| 2007 |
Escoubas P, Bosmans F. Spider peptide toxins as leads for drug development. Expert Opinion On Drug Discovery. 2: 823-35. PMID 23489000 DOI: 10.1517/17460441.2.6.823 |
0.362 |
|
| 2007 |
Bosmans F, Tytgat J. Sea anemone venom as a source of insecticidal peptides acting on voltage-gated Na+ channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 550-60. PMID 17224168 DOI: 10.1016/J.Toxicon.2006.11.029 |
0.614 |
|
| 2007 |
Corzo G, Sabo JK, Bosmans F, Billen B, Villegas E, Tytgat J, Norton RS. Solution structure and alanine scan of a spider toxin that affects the activation of mammalian voltage-gated sodium channels. The Journal of Biological Chemistry. 282: 4643-52. PMID 17148449 DOI: 10.1074/Jbc.M605403200 |
0.636 |
|
| 2007 |
Bosmans F, Martin-Eauclaire MF, Tytgat J. Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity. Toxicology and Applied Pharmacology. 218: 45-51. PMID 17118417 DOI: 10.1016/J.Taap.2006.10.009 |
0.54 |
|
| 2007 |
Bosmans F, Tytgat J. Voltage-gated sodium channel modulation by scorpion alpha-toxins. Toxicon : Official Journal of the International Society On Toxinology. 49: 142-58. PMID 17087986 DOI: 10.1016/J.Toxicon.2006.09.023 |
0.604 |
|
| 2006 |
Abdel-Mottaleb Y, Clynen E, Jalali A, Bosmans F, Vatanpour H, Schoofs L, Tytgat J. The first potassium channel toxin from the venom of the Iranian scorpion Odonthobuthus doriae. Febs Letters. 580: 6254-8. PMID 17070524 DOI: 10.1016/J.Febslet.2006.10.029 |
0.568 |
|
| 2006 |
Bosmans F, Rash L, Zhu S, Diochot S, Lazdunski M, Escoubas P, Tytgat J. Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes. Molecular Pharmacology. 69: 419-29. PMID 16267209 DOI: 10.1124/Mol.105.015941 |
0.57 |
|
| 2005 |
Ye X, Bosmans F, Li C, Zhang Y, Wang DC, Tytgat J. Structural basis for the voltage-gated Na+ channel selectivity of the scorpion alpha-like toxin BmK M1. Journal of Molecular Biology. 353: 788-803. PMID 16209876 DOI: 10.1016/J.Jmb.2005.08.068 |
0.508 |
|
| 2005 |
Jalali A, Bosmans F, Amininasab M, Clynen E, Cuypers E, Zaremirakabadi A, Sarbolouki MN, Schoofs L, Vatanpour H, Tytgat J. OD1, the first toxin isolated from the venom of the scorpion Odonthobuthus doriae active on voltage-gated Na+ channels. Febs Letters. 579: 4181-6. PMID 16038905 DOI: 10.1016/J.Febslet.2005.06.052 |
0.492 |
|
| 2005 |
Martin-Eauclaire MF, Ceard B, Bosmans F, Rosso JP, Tytgat J, Bougis PE. New "Birtoxin analogs" from Androctonus australis venom. Biochemical and Biophysical Research Communications. 333: 524-30. PMID 15963953 DOI: 10.1016/J.Bbrc.2005.05.148 |
0.542 |
|
| 2005 |
Bosmans F, Brône B, Sun YM, Zhu RH, Xiong YM, Wang DC, Van Kerkhove E, Tytgat J. Pharmacological comparison of two different insect models using the scorpion alpha-like toxin BmK M1 from Buthus martensii Karsch. Protein and Peptide Letters. 12: 363-7. PMID 15907182 DOI: 10.2174/0929866053765635 |
0.374 |
|
| 2005 |
Bosmans F, Martin-Eauclaire MF, Tytgat J. The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel. Toxicon : Official Journal of the International Society On Toxinology. 45: 501-7. PMID 15733572 DOI: 10.1016/J.Toxicon.2004.12.010 |
0.599 |
|
| 2005 |
Ferrat G, Bosmans F, Tytgat J, Pimentel C, Chagot B, Gilles N, Nakajima T, Darbon H, Corzo G. Solution structure of two insect-specific spider toxins and their pharmacological interaction with the insect voltage-gated Na+ channel Proteins. 59: 368-379. PMID 15726637 DOI: 10.1002/Prot.20424 |
0.581 |
|
| 2005 |
Arnon T, Potikha T, Sher D, Elazar M, Mao W, Tal T, Bosmans F, Tytgat J, Ben-Arie N, Zlotkin E. BjalphaIT: a novel scorpion alpha-toxin selective for insects--unique pharmacological tool. Insect Biochemistry and Molecular Biology. 35: 187-95. PMID 15705498 DOI: 10.1016/J.Ibmb.2004.11.005 |
0.486 |
|
| 2005 |
Liu LH, Bosmans F, Maertens C, Zhu RH, Wang DC, Tytgat J. Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 594-6. PMID 15677695 DOI: 10.1096/Fj.04-2485Fje |
0.519 |
|
| 2004 |
Valdez-Cruz NA, Batista CV, Zamudio FZ, Bosmans F, Tytgat J, Possani LD. Phaiodotoxin, a novel structural class of insect-toxin isolated from the venom of the Mexican scorpion Anuroctonus phaiodactylus. European Journal of Biochemistry. 271: 4753-61. PMID 15606762 DOI: 10.1111/J.1432-1033.2004.04439.X |
0.399 |
|
| 2004 |
Bosmans F, Maertens C, Verdonck F, Tytgat J. The poison Dart frog's batrachotoxin modulates Nav1.8. Febs Letters. 577: 245-8. PMID 15527793 DOI: 10.1016/J.Febslet.2004.10.017 |
0.603 |
|
| 2004 |
Zhu S, Bosmans F, Tytgat J. Adaptive evolution of scorpion sodium channel toxins. Journal of Molecular Evolution. 58: 145-53. PMID 15042334 DOI: 10.1007/S00239-003-2534-2 |
0.407 |
|
| 2003 |
Li D, Xiao Y, Hu W, Xie J, Bosmans F, Tytgat J, Liang S. Function and solution structure of hainantoxin-I, a novel insect sodium channel inhibitor from the Chinese bird spider Selenocosmia hainana. Febs Letters. 555: 616-22. PMID 14675784 DOI: 10.1016/S0014-5793(03)01303-6 |
0.536 |
|
| 2003 |
Alami M, Vacher H, Bosmans F, Devaux C, Rosso JP, Bougis PE, Tytgat J, Darbon H, Martin-Eauclaire MF. Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels. The Biochemical Journal. 375: 551-60. PMID 12911331 DOI: 10.1042/Bj20030688 |
0.486 |
|
| 2003 |
Sun YM, Bosmans F, Zhu RH, Goudet C, Xiong YM, Tytgat J, Wang DC. Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited. The Journal of Biological Chemistry. 278: 24125-31. PMID 12692120 DOI: 10.1074/Jbc.M211931200 |
0.455 |
|
| 2002 |
Bosmans F, Aneiros A, Tytgat J. The sea anemone Bunodosoma granulifera contains surprisingly efficacious and potent insect-selective toxins. Febs Letters. 532: 131-4. PMID 12459477 DOI: 10.1016/S0014-5793(02)03653-0 |
0.585 |
|
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