Frank Bosmans - Publications

Affiliations: 
2006-2012 Physiology Johns Hopkins University School of Medicine, Baltimore, MD, United States 

41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Herzig V, Sunagar K, Wilson DTR, Pineda SS, Israel MR, Dutertre S, McFarland BS, Undheim EAB, Hodgson WC, Alewood PF, Lewis RJ, Bosmans F, Vetter I, King GF, Fry BG. Australian funnel-web spiders evolved human-lethal δ-hexatoxins for defense against vertebrate predators. Proceedings of the National Academy of Sciences of the United States of America. PMID 32958636 DOI: 10.1073/pnas.2004516117  0.32
2020 Rupasinghe DB, Herzig V, Vetter I, Dekan Z, Gilchrist J, Bosmans F, Alewood PF, Lewis RJ, King GF. Mutational analysis of ProTx-I and the novel venom peptide Pe1b provide insight into residues responsible for selective inhibition of the analgesic drug target Na1.7. Biochemical Pharmacology. 114080. PMID 32511987 DOI: 10.1016/j.bcp.2020.114080  0.32
2019 Clairfeuille T, Cloake A, Infield DT, Llongueras JP, Arthur CP, Li ZR, Jian Y, Martin-Eauclaire MF, Bougis PE, Ciferri C, Ahern CA, Bosmans F, Hackos DH, Rohou A, Payandeh J. Structural basis of α-scorpion toxin action on Nav channels. Science (New York, N.Y.). PMID 30733386 DOI: 10.1126/science.aav8573  0.56
2018 Salvatierra J, Diaz-Bustamante M, Meixiong J, Tierney E, Dong X, Bosmans F. A disease mutation reveals a role for NaV1.9 in acute itch. The Journal of Clinical Investigation. PMID 30395542 DOI: 10.1172/JCI122481  0.32
2018 Martin-Eauclaire MF, Salvatierra J, Mansuelle P, Bosmans F, Bougis PE. The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension. Febs Letters. 592: 2668. PMID 30168598 DOI: 10.1002/1873-3468.13185  0.56
2018 Salvatierra J, Castro J, Erickson A, Li Q, Braz J, Gilchrist J, Grundy L, Rychkov GY, Deiteren A, Rais R, King GF, Slusher BS, Basbaum A, Pasricha PJ, Brierley SM, ... Bosmans F, et al. NaV1.1 inhibition can reduce visceral hypersensitivity. Jci Insight. 3. PMID 29875317 DOI: 10.1172/jci.insight.121000  0.32
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Corrigendum: Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 46816. PMID 28548111 DOI: 10.1038/srep46816  0.32
2017 Smith JJ, Herzig V, Ikonomopoulou MP, Dziemborowicz S, Bosmans F, Nicholson GM, King GF. Insect-Active Toxins with Promiscuous Pharmacology from the African Theraphosid Spider Monocentropus balfouri. Toxins. 9. PMID 28475112 DOI: 10.3390/toxins9050155  0.32
2017 Deuis JR, Dekan Z, Wingerd JS, Smith JJ, Munasinghe NR, Bhola RF, Imlach WL, Herzig V, Armstrong DA, Rosengren KJ, Bosmans F, Waxman SG, Dib-Hajj SD, Escoubas P, Minett MS, et al. Pharmacological characterisation of the highly NaV1.7 selective spider venom peptide Pn3a. Scientific Reports. 7: 40883. PMID 28106092 DOI: 10.1038/srep40883  0.32
2016 Ikonomopoulou MP, Smith JJ, Herzig V, Pineda SS, Dziemborowicz S, Er SY, Durek T, Gilchrist J, Alewood PF, Nicholson GM, Bosmans F, King GF. Isolation of two insecticidal toxins from venom of the Australian theraphosid spider Coremiocnemis tropix. Toxicon : Official Journal of the International Society On Toxinology. PMID 27793656 DOI: 10.1016/j.toxicon.2016.10.013  0.32
2016 Martin-Eauclaire MF, Salvatierra J, Bosmans F, Bougis PE. The scorpion toxin Bot IX is a potent member of the α-like family and has a unique N-terminal sequence extension. Febs Letters. 590: 3221-32. PMID 27528512 DOI: 10.1002/1873-3468.12357  0.56
2016 Herzig V, Ikonomopoulou M, Smith JJ, Dziemborowicz S, Gilchrist J, Kuhn-Nentwig L, Rezende FO, Moreira LA, Nicholson GM, Bosmans F, King GF. Molecular basis of the remarkable species selectivity of an insecticidal sodium channel toxin from the African spider Augacephalus ezendami. Scientific Reports. 6: 29538. PMID 27383378 DOI: 10.1038/srep29538  0.32
2016 Osteen JD, Herzig V, Gilchrist J, Emrick JJ, Zhang C, Wang X, Castro J, Garcia-Caraballo S, Grundy L, Rychkov GY, Weyer AD, Dekan Z, Undheim EA, Alewood P, Stucky CL, ... ... Bosmans F, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. PMID 27281198 DOI: 10.1038/nature17976  0.32
2016 Kwon S, Bosmans F, Kaas Q, Cheneval O, Conibear AC, Rosengren KJ, Wang CK, Schroeder CI, Craik DJ. Efficient enzymatic cyclization of an inhibitory cystine knot-containing peptide. Biotechnology and Bioengineering. PMID 27093300 DOI: 10.1002/bit.25993  0.52
2016 Salvatierra J, Bosmans F. A painful tale about synthetic scorpion toxins. Channels (Austin, Tex.). 10: 256-7. PMID 26962885 DOI: 10.1080/19336950.2016.1163956  0.32
2016 Das S, Gilchrist J, Bosmans F, Van Petegem F. Binary architecture of the Nav1.2-β2 signaling complex. Elife. 5. PMID 26894959 DOI: 10.7554/eLife.10960  0.52
2016 Ahern CA, Payandeh J, Bosmans F, Chanda B. The hitchhiker's guide to the voltage-gated sodium channel galaxy. The Journal of General Physiology. 147: 1-24. PMID 26712848 DOI: 10.1085/jgp.201511492  0.52
2015 Camargos TS, Bosmans F, Rego SC, Mourão CB, Schwartz EF. The Scorpion Toxin Tf2 from Tityus fasciolatus Promotes Nav1.3 Opening. Plos One. 10: e0128578. PMID 26083731 DOI: 10.1371/journal.pone.0128578  0.52
2015 Klint JK, Smith JJ, Vetter I, Rupasinghe DB, Er SY, Senff S, Herzig V, Mobli M, Lewis RJ, Bosmans F, King GF. Seven novel modulators of the analgesic target NaV 1.7 uncovered using a high-throughput venom-based discovery approach. British Journal of Pharmacology. 172: 2445-58. PMID 25754331 DOI: 10.1111/bph.13081  0.52
2015 Martin-Eauclaire MF, Ferracci G, Bosmans F, Bougis PE. A surface plasmon resonance approach to monitor toxin interactions with an isolated voltage-gated sodium channel paddle motif. The Journal of General Physiology. 145: 155-62. PMID 25624450 DOI: 10.1085/jgp.201411268  0.56
2015 Bende NS, Dziemborowicz S, Herzig V, Ramanujam V, Brown GW, Bosmans F, Nicholson GM, King GF, Mobli M. The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop. The Febs Journal. 282: 904-20. PMID 25559770 DOI: 10.1111/febs.13189  0.52
2015 Kalia J, Milescu M, Salvatierra J, Wagner J, Klint JK, King GF, Olivera BM, Bosmans F. From foe to friend: using animal toxins to investigate ion channel function. Journal of Molecular Biology. 427: 158-75. PMID 25088688 DOI: 10.1016/j.jmb.2014.07.027  0.52
2015 Rosso JP, Schwarz JR, Diaz-Bustamante M, Céard B, Gutiérrez JM, Kneussel M, Pongs O, Bosmans F, Bougis PE. MmTX1 and MmTX2 from coral snake venom potently modulate receptor activity modulate GABAa receptor activity Proceedings of the National Academy of Sciences of the United States of America. 112: E891-E900. DOI: 10.1073/pnas.1415488112  0.52
2014 Bende NS, Dziemborowicz S, Mobli M, Herzig V, Gilchrist J, Wagner J, Nicholson GM, King GF, Bosmans F. A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a. Nature Communications. 5: 4350. PMID 25014760 DOI: 10.1038/ncomms5350  0.32
2014 Gilchrist J, Olivera BM, Bosmans F. Animal toxins influence voltage-gated sodium channel function. Handbook of Experimental Pharmacology. 221: 203-29. PMID 24737238 DOI: 10.1007/978-3-642-41588-3_10  0.52
2014 Gilchrist J, Dutton S, Diaz-Bustamante M, McPherson A, Olivares N, Kalia J, Escayg A, Bosmans F. Nav1.1 modulation by a novel triazole compound attenuates epileptic seizures in rodents. Acs Chemical Biology. 9: 1204-12. PMID 24635129 DOI: 10.1021/cb500108p  0.52
2014 Martin-Eauclaire MF, Bosmans F, Céard B, Diochot S, Bougis PE. A first exploration of the venom of the Buthus occitanus scorpion found in southern France. Toxicon : Official Journal of the International Society On Toxinology. 79: 55-63. PMID 24418174 DOI: 10.1016/j.toxicon.2014.01.002  0.56
2013 Gilchrist J, Das S, Van Petegem F, Bosmans F. Crystallographic insights into sodium-channel modulation by the β4 subunit. Proceedings of the National Academy of Sciences of the United States of America. 110: E5016-24. PMID 24297919 DOI: 10.1073/pnas.1314557110  0.52
2013 Bende NS, Kang E, Herzig V, Bosmans F, Nicholson GM, Mobli M, King GF. The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels. Biochemical Pharmacology. 85: 1542-54. PMID 23473802 DOI: 10.1016/j.bcp.2013.02.030  0.32
2011 Bosmans F, Milescu M, Swartz KJ. Palmitoylation influences the function and pharmacology of sodium channels. Proceedings of the National Academy of Sciences of the United States of America. 108: 20213-8. PMID 22123950 DOI: 10.1073/pnas.1108497108  1
2011 Bosmans F, Puopolo M, Martin-Eauclaire MF, Bean BP, Swartz KJ. Functional properties and toxin pharmacology of a dorsal root ganglion sodium channel viewed through its voltage sensors. The Journal of General Physiology. 138: 59-72. PMID 21670206 DOI: 10.1085/jgp.201110614  0.52
2010 Bosmans F, Swartz KJ. Targeting voltage sensors in sodium channels with spider toxins. Trends in Pharmacological Sciences. 31: 175-82. PMID 20097434 DOI: 10.1016/j.tips.2009.12.007  1
2009 Milescu M, Bosmans F, Lee S, Alabi AA, Kim JI, Swartz KJ. Interactions between lipids and voltage sensor paddles detected with tarantula toxins. Nature Structural & Molecular Biology. 16: 1080-5. PMID 19783984 DOI: 10.1038/nsmb.1679  1
2008 Bosmans F, Martin-Eauclaire MF, Swartz KJ. Deconstructing voltage sensor function and pharmacology in sodium channels. Nature. 456: 202-8. PMID 19005548 DOI: 10.1038/nature07473  1
2007 Bosmans F, Martin-Eauclaire MF, Tytgat J. Differential effects of five 'classical' scorpion beta-toxins on rNav1.2a and DmNav1 provide clues on species-selectivity. Toxicology and Applied Pharmacology. 218: 45-51. PMID 17118417 DOI: 10.1016/j.taap.2006.10.009  0.56
2005 Martin-Eauclaire MF, Ceard B, Bosmans F, Rosso JP, Tytgat J, Bougis PE. New "Birtoxin analogs" from Androctonus australis venom. Biochemical and Biophysical Research Communications. 333: 524-30. PMID 15963953 DOI: 10.1016/j.bbrc.2005.05.148  0.56
2005 Bosmans F, Martin-Eauclaire MF, Tytgat J. The depressant scorpion neurotoxin LqqIT2 selectively modulates the insect voltage-gated sodium channel. Toxicon : Official Journal of the International Society On Toxinology. 45: 501-7. PMID 15733572 DOI: 10.1016/j.toxicon.2004.12.010  0.56
2005 Arnon T, Potikha T, Sher D, Elazar M, Mao W, Tal T, Bosmans F, Tytgat J, Ben-Arie N, Zlotkin E. BjalphaIT: a novel scorpion alpha-toxin selective for insects--unique pharmacological tool. Insect Biochemistry and Molecular Biology. 35: 187-95. PMID 15705498 DOI: 10.1016/j.ibmb.2004.11.005  0.52
2005 Liu LH, Bosmans F, Maertens C, Zhu RH, Wang DC, Tytgat J. Molecular basis of the mammalian potency of the scorpion alpha-like toxin, BmK M1. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 594-6. PMID 15677695 DOI: 10.1096/fj.04-2485fje  0.52
2004 Bosmans F, Maertens C, Verdonck F, Tytgat J. The poison Dart frog's batrachotoxin modulates Nav1.8. Febs Letters. 577: 245-8. PMID 15527793 DOI: 10.1016/j.febslet.2004.10.017  0.52
2003 Alami M, Vacher H, Bosmans F, Devaux C, Rosso JP, Bougis PE, Tytgat J, Darbon H, Martin-Eauclaire MF. Characterization of Amm VIII from Androctonus mauretanicus mauretanicus: a new scorpion toxin that discriminates between neuronal and skeletal sodium channels. The Biochemical Journal. 375: 551-60. PMID 12911331 DOI: 10.1042/BJ20030688  0.56
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