| Year |
Citation |
Score |
| 2008 |
Patel DC, Pavitt D, Albrecht C, Dhanjil S, Hannen R, Valabhji J, Higgins CF, Johnston DG. Hyperglycaemic patients have decreased ATP-binding cassette transporter-A1 (ABCA-1) gene expression: A novel disease mechanism Atherosclerosis. 199: 231-232. DOI: 10.1016/J.Atherosclerosis.2008.04.026 |
0.359 |
|
| 2007 |
Randle RA, Raguz S, Higgins CF, Yagüe E. Role of the highly structured 5'-end region of MDR1 mRNA in P-glycoprotein expression. The Biochemical Journal. 406: 445-55. PMID 17573715 DOI: 10.1042/Bj20070235 |
0.351 |
|
| 2007 |
Higgins CF. Multiple molecular mechanisms for multidrug resistance transporters. Nature. 446: 749-57. PMID 17429392 DOI: 10.1038/Nature05630 |
0.342 |
|
| 2007 |
Weylandt KH, Nebrig M, Jansen-Rosseck N, Amey JS, Carmena D, Wiedenmann B, Higgins CF, Sardini A. ClC-3 expression enhances etoposide resistance by increasing acidification of the late endocytic compartment. Molecular Cancer Therapeutics. 6: 979-86. PMID 17363491 DOI: 10.1158/1535-7163.Mct-06-0475 |
0.339 |
|
| 2007 |
Stieger B, Higgins CF. Twenty years of ATP-binding cassette (ABC) transporters. PflüGers Archiv : European Journal of Physiology. 453: 543. PMID 17091310 DOI: 10.1007/S00424-006-0159-1 |
0.439 |
|
| 2007 |
Linton KJ, Higgins CF. Structure and function of ABC transporters: the ATP switch provides flexible control. PflüGers Archiv : European Journal of Physiology. 453: 555-67. PMID 16937116 DOI: 10.1007/S00424-006-0126-X |
0.381 |
|
| 2006 |
Okkenhaug H, Weylandt KH, Carmena D, Wells DJ, Higgins CF, Sardini A. The human ClC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2390-2. PMID 17023393 DOI: 10.1096/Fj.05-5588Fje |
0.35 |
|
| 2005 |
Elliott JI, Surprenant A, Marelli-Berg FM, Cooper JC, Cassady-Cain RL, Wooding C, Linton K, Alexander DR, Higgins CF. Membrane phosphatidylserine distribution as a non-apoptotic signalling mechanism in lymphocytes. Nature Cell Biology. 7: 808-16. PMID 16025105 DOI: 10.1038/Ncb1279 |
0.347 |
|
| 2005 |
Albrecht C, McVey JH, Elliott JI, Sardini A, Kasza I, Mumford AD, Naoumova RP, Tuddenham EG, Szabo K, Higgins CF. A novel missense mutation in ABCA1 results in altered protein trafficking and reduced phosphatidylserine translocation in a patient with Scott syndrome. Blood. 106: 542-9. PMID 15790791 DOI: 10.1182/Blood-2004-05-2056 |
0.333 |
|
| 2005 |
Begley GS, Horvath AR, Taylor JC, Higgins CF. Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome. Molecular Immunology. 42: 137-41. PMID 15488952 DOI: 10.1016/J.Molimm.2004.07.005 |
0.364 |
|
| 2005 |
Rosenberg MF, Callaghan R, Modok S, Higgins CF, Ford RC. Three-dimensional structure of P-glycoprotein: the transmembrane regions adopt an asymmetric configuration in the nucleotide-bound state. The Journal of Biological Chemistry. 280: 2857-62. PMID 15485807 DOI: 10.1074/Jbc.M410296200 |
0.368 |
|
| 2004 |
Elliott JI, Raguz S, Higgins CF. Multidrug transporter activity in lymphocytes. British Journal of Pharmacology. 143: 899-907. PMID 15492020 DOI: 10.1038/Sj.Bjp.0705940 |
0.375 |
|
| 2004 |
Higgins CF, Linton KJ. The ATP switch model for ABC transporters. Nature Structural & Molecular Biology. 11: 918-26. PMID 15452563 DOI: 10.1038/Nsmb836 |
0.376 |
|
| 2004 |
Albrecht C, Baynes K, Sardini A, Schepelmann S, Eden ER, Davies SW, Higgins CF, Feher MD, Owen JS, Soutar AK. Two novel missense mutations in ABCA1 result in altered trafficking and cause severe autosomal recessive HDL deficiency. Biochimica Et Biophysica Acta. 1689: 47-57. PMID 15158913 DOI: 10.1016/J.Bbadis.2004.01.007 |
0.307 |
|
| 2004 |
Albrecht C, Simon-Vermot I, Elliott JI, Higgins CF, Johnston DG, Valabhji J. Leukocyte ABCA1 gene expression is associated with fasting glucose concentration in normoglycemic men Metabolism: Clinical and Experimental. 53: 17-21. PMID 14681836 DOI: 10.1016/J.Metabol.2003.07.009 |
0.316 |
|
| 2003 |
Jodoin J, Demeule M, Fenart L, Cecchelli R, Farmer S, Linton KJ, Higgins CF, Béliveau R. P-glycoprotein in blood-brain barrier endothelial cells: interaction and oligomerization with caveolins. Journal of Neurochemistry. 87: 1010-23. PMID 14622130 DOI: 10.1046/J.1471-4159.2003.02081.X |
0.325 |
|
| 2003 |
Stenham DR, Campbell JD, Sansom MS, Higgins CF, Kerr ID, Linton KJ. An atomic detail model for the human ATP binding cassette transporter P-glycoprotein derived from disulfide cross-linking and homology modeling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 2287-9. PMID 14563687 DOI: 10.1096/Fj.03-0107Fje |
0.387 |
|
| 2003 |
Kerr ID, Berridge G, Linton KJ, Higgins CF, Callaghan R. Definition of the domain boundaries is critical to the expression of the nucleotide-binding domains of P-glycoprotein. European Biophysics Journal : Ebj. 32: 644-54. PMID 12830334 DOI: 10.1007/S00249-003-0327-6 |
0.366 |
|
| 2003 |
Müllenbach R, Linton KJ, Wiltshire S, Weerasekera N, Chambers J, Elias E, Higgins CF, Johnston DG, McCarthy MI, Williamson C. ABCB4 gene sequence variation in women with intrahepatic cholestasis of pregnancy Journal of Medical Genetics. 40. PMID 12746424 DOI: 10.1136/Jmg.40.5.E70 |
0.329 |
|
| 2002 |
Albrecht C, Elliott JI, Sardini A, Litman T, Stieger B, Meier PJ, Higgins CF. Functional analysis of candidate ABC transporter proteins for sitosterol transport Biochimica Et Biophysica Acta - Biomembranes. 1567: 133-142. PMID 12488046 DOI: 10.1016/S0005-2736(02)00608-9 |
0.418 |
|
| 2002 |
Esposito D, Petrovic A, Harris R, Ono S, Eccleston JF, Mbabaali A, Haq I, Higgins CF, Hinton JC, Driscoll PC, Ladbury JE. H-NS oligomerization domain structure reveals the mechanism for high order self-association of the intact protein. Journal of Molecular Biology. 324: 841-50. PMID 12460581 DOI: 10.1016/S0022-2836(02)01141-5 |
0.308 |
|
| 2002 |
Byrne JA, Strautnieks SS, Mieli-Vergani G, Higgins CF, Linton KJ, Thompson RJ. The human bile salt export pump: characterization of substrate specificity and identification of inhibitors. Gastroenterology. 123: 1649-58. PMID 12404239 DOI: 10.1053/Gast.2002.36591 |
0.34 |
|
| 2002 |
Linton KJ, Higgins CF. P-glycoprotein misfolds in Escherichia coli: evidence against alternating-topology models of the transport cycle. Molecular Membrane Biology. 19: 51-8. PMID 11989822 DOI: 10.1080/09687680110103622 |
0.38 |
|
| 2002 |
Linton KJ, Higgins CF. The Escherichia coli ATP-binding cassette (ABC) proteins. Molecular Microbiology. 28: 5-13. PMID 9593292 DOI: 10.1046/J.1365-2958.1998.00764.X |
0.407 |
|
| 2001 |
Martin C, Higgins CF, Callaghan R. The vinblastine binding site adopts high- and low-affinity conformations during a transport cycle of P-glycoprotein. Biochemistry. 40: 15733-15742. PMID 11747450 DOI: 10.1021/Bi011211Z |
0.335 |
|
| 2001 |
Taylor AM, Storm J, Soceneantu L, Linton KJ, Gabriel M, Martin C, Woodhouse J, Blott E, Higgins CF, Callaghan R. Detailed characterization of cysteine-less P-glycoprotein reveals subtle pharmacological differences in function from wild-type protein. British Journal of Pharmacology. 134: 1609-18. PMID 11739236 DOI: 10.1038/Sj.Bjp.0704400 |
0.351 |
|
| 2001 |
Rothnie A, Theron D, Soceneantu L, Martin C, Traikia M, Berridge G, Higgins CF, Devaux PF, Callaghan R. The importance of cholesterol in maintenance of P-glycoprotein activity and its membrane perturbing influence. European Biophysics Journal. 30: 430-442. PMID 11718296 DOI: 10.1007/S002490100156 |
0.309 |
|
| 2001 |
Rosenberg MF, Velarde G, Ford RC, Martin C, Berridge G, Kerr ID, Callaghan R, Schmidlin A, Wooding C, Linton KJ, Higgins CF. Repacking of the transmembrane domains of P-glycoprotein during the transport ATPase cycle. The Embo Journal. 20: 5615-25. PMID 11598005 DOI: 10.1093/Emboj/20.20.5615 |
0.398 |
|
| 2001 |
Higgins CF, Linton KJ. The xyz of ABC Transporters Science. 293: 1782-1784. PMID 11546861 DOI: 10.1126/Science.1065588 |
0.374 |
|
| 2001 |
Taylor JC, Horvath AR, Higgins CF, Begley GS. The multidrug resistance P-glycoprotein. Oligomeric state and intramolecular interactions. Journal of Biological Chemistry. 276: 36075-36078. PMID 11495894 DOI: 10.1074/Jbc.C100345200 |
0.391 |
|
| 2001 |
van Veen HW, Higgins CF, Konings WN. Multidrug transport by ATP binding cassette transporters: a proposed two-cylinder engine mechanism. Research in Microbiology. 152: 365-74. PMID 11421284 DOI: 10.1016/S0923-2508(01)01208-6 |
0.391 |
|
| 2001 |
Higgins CF. ABC transporters: physiology, structure and mechanism--an overview. Research in Microbiology. 152: 205-210. PMID 11421269 DOI: 10.1016/S0923-2508(01)01193-7 |
0.393 |
|
| 2001 |
Weylandt KH, Valverde MA, Nobles M, Raguz S, Amey JS, Diaz M, Nastrucci C, Higgins CF, Sardini A. Human ClC-3 is not the swelling-activated chloride channel involved in cell volume regulation. The Journal of Biological Chemistry. 276: 17461-7. PMID 11278960 DOI: 10.1074/Jbc.M011667200 |
0.327 |
|
| 2001 |
Sonnenfield JM, Burns CM, Higgins CF, Hinton JCD. The nucleoid-associated protein StpA binds curved DNA, has a greater DNA-binding affinity than H-NS and is present in significant levels in hns mutants Biochimie. 83: 243-249. PMID 11278075 DOI: 10.1016/S0300-9084(01)01232-9 |
0.341 |
|
| 2000 |
Krauzewicz N, Stokrová J, Jenkins C, Elliott M, Higgins CF, Griffin BE. Virus-like gene transfer into cells mediated by polyoma virus pseudocapsids. Gene Therapy. 7: 2122-2131. PMID 11223994 DOI: 10.1038/Sj.Gt.3301322 |
0.342 |
|
| 2000 |
Martin C, Berridge G, Mistry P, Higgins C, Charlton P, Callaghan R. Drug binding sites on P-glycoprotein are altered by ATP binding prior to nucleotide hydrolysis. Biochemistry. 39: 11901-11906. PMID 11009602 DOI: 10.1021/Bi000559B |
0.368 |
|
| 2000 |
Martin C, Berridge G, Higgins CF, Mistry P, Charlton P, Callaghan R. Communication between Multiple Drug Binding Sites on P-glycoprotein Molecular Pharmacology. 58: 624-632. PMID 10953057 DOI: 10.1124/Mol.58.3.624 |
0.348 |
|
| 2000 |
Smyth CP, Lundbäck T, Renzoni D, Siligardi G, Beavil R, Layton M, Sidebotham JM, Hinton JC, Driscoll PC, Higgins CF, Ladbury JE. Oligomerization of the chromatin-structuring protein H-NS. Molecular Microbiology. 36: 962-72. PMID 10844682 DOI: 10.1046/J.1365-2958.2000.01917.X |
0.351 |
|
| 2000 |
van Veen HW, Margolles A, Müller M, Higgins CF, Konings WN. The homodimeric ATP-binding cassette transporter LmrA mediates multidrug transport by an alternating two-site (two-cylinder engine) mechanism. The Embo Journal. 19: 2503-14. PMID 10835349 DOI: 10.1093/Emboj/19.11.2503 |
0.389 |
|
| 2000 |
Jordi BJ, Higgins CF. The downstream regulatory element of the proU operon of Salmonella typhimurium inhibits open complex formation by RNA polymerase at a distance. The Journal of Biological Chemistry. 275: 12123-8. PMID 10766847 DOI: 10.1074/Jbc.275.16.12123 |
0.326 |
|
| 2000 |
ISHIKAWA T, ALLIKIMETS R, DEAN M, HIGGINS C, LING V, WAIN HM. New Nomenclature of Human ABC Transporter Genes. Drug Metabolism and Pharmacokinetics. 15: 8-19. DOI: 10.2133/Dmpk.15.8 |
0.39 |
|
| 2000 |
Higgins CF. ABC transporters and multidrug resistance Biochemical Society Transactions. 28. DOI: 10.1042/Bst028A066A |
0.327 |
|
| 1999 |
Blott EJ, Higgins CF, Linton KJ. Cysteine-scanning mutagenesis provides no evidence for the extracellular accessibility of the nucleotide-binding domains of the multidrug resistance transporter P-glycoprotein. The Embo Journal. 18: 6800-6808. PMID 10581253 DOI: 10.1093/Emboj/18.23.6800 |
0.407 |
|
| 1999 |
Taylor JC, Ferry DR, Higgins CF, Callaghan R. The equilibrium and kinetic drug binding properties of the mouse P-gp1a and P-gp1b P-glycoproteins are similar. British Journal of Cancer. 81: 783-789. PMID 10555746 DOI: 10.1038/Sj.Bjc.6690764 |
0.338 |
|
| 1999 |
Martin C, Berridge G, Mistry P, Higgins C, Charlton P, Callaghan R. The molecular interaction of the high affinity reversal agent XR9576 with P-glycoprotein British Journal of Pharmacology. 128: 403-411. PMID 10510451 DOI: 10.1038/Sj.Bjp.0702807 |
0.337 |
|
| 1999 |
Higgins CF. Membrane permeability transporters and channels: from disease to structure and back: Editorial overview Current Opinion in Cell Biology. 11: 495-495. DOI: 10.1016/S0955-0674(99)80071-4 |
0.32 |
|
| 1998 |
Bond TD, Higgins CF, Valverde MA. P-glycoprotein and swelling-activated chloride channels. Methods in Enzymology. 292: 359-70. PMID 9711567 DOI: 10.1016/S0076-6879(98)92028-6 |
0.341 |
|
| 1998 |
Singer TD, Tucker SJ, Marshall WS, Higgins CF. A divergent CFTR homologue: highly regulated salt transport in the euryhaline teleost F. heteroclitus. The American Journal of Physiology. 274: C715-23. PMID 9530103 DOI: 10.1152/Ajpcell.1998.274.3.C715 |
0.569 |
|
| 1998 |
Bond TD, Valverde MA, Higgins CF. Protein kinase C phosphorylation disengages human and mouse-1a P-glycoproteins from influencing the rate of activation of swelling-activated chloride currents. The Journal of Physiology. 508: 333-40. PMID 9508799 DOI: 10.1111/J.1469-7793.1998.333Bq.X |
0.305 |
|
| 1998 |
White NL, Higgins CF, Trezise AEO. Tissue-Specific in Vivo Transcription Start Sites of the Human and Murine Cystic Fibrosis Genes Human Molecular Genetics. 7: 363-369. PMID 9466991 DOI: 10.1093/Hmg/7.3.363 |
0.324 |
|
| 1998 |
van Veen HW, Callaghan R, Soceneantu L, Sardini A, Konings WN, Higgins CF. A bacterial antibiotic-resistance gene that complements the human multidrug-resistance P-glycoprotein gene. Nature. 391: 291-5. PMID 9440694 DOI: 10.1038/34669 |
0.36 |
|
| 1997 |
Higgins CF, Callaghan R, Linton KJ, Rosenberg MF, Ford RC. Structure of the multidrug resistance P-glycoprotein. Seminars in Cancer Biology. 8: 135-42. PMID 9441943 DOI: 10.1006/Scbi.1997.0067 |
0.313 |
|
| 1997 |
Martin C, Berridge G, Higgins CF, Callaghan R. The multi‐drug resistance reversal agent SR33557 and modulation of vinca alkaloid binding to P‐glycoprotein by an allosteric interaction British Journal of Pharmacology. 122: 765-771. PMID 9375975 DOI: 10.1038/Sj.Bjp.0701429 |
0.335 |
|
| 1997 |
Callaghan R, Berridge G, Ferry DR, Higgins CF. The functional purification of P-glycoprotein is dependent on maintenance of a lipid–protein interface Biochimica Et Biophysica Acta. 1328: 109-124. PMID 9315609 DOI: 10.1016/S0005-2736(97)00079-5 |
0.331 |
|
| 1997 |
Mojica FJM, Higgins CF. In vivo supercoiling of plasmid and chromosomal DNA in an Escherichia coli hns mutant. Journal of Bacteriology. 179: 3528-3533. PMID 9171396 DOI: 10.1128/Jb.179.11.3528-3533.1997 |
0.311 |
|
| 1997 |
Jordi BJAM, Fielder AE, Burns CM, Hinton JCD, Dover N, Ussery DW, Higgins CF. DNA binding is not sufficient for H-NS-mediated repression of proU expression Journal of Biological Chemistry. 272: 12083-12090. PMID 9115277 DOI: 10.1074/Jbc.272.18.12083 |
0.32 |
|
| 1997 |
Gileadi U, Higgins CF. Membrane topology of the ATP-binding cassette transporter associated with antigen presentation (Tap1) expressed in Escherichia coli. Journal of Biological Chemistry. 272: 11103-11108. PMID 9111005 DOI: 10.1074/Jbc.272.17.11103 |
0.402 |
|
| 1997 |
Trezise AE, Ratcliff R, Hawkins TE, Evans MJ, Freeman TC, Romano PR, Higgins CF, Colledge WH. Co-ordinate regulation of the cystic fibrosis and multidrug resistance genes in cystic fibrosis knockout mice. Human Molecular Genetics. 6: 527-37. PMID 9097955 DOI: 10.1093/Hmg/6.4.527 |
0.333 |
|
| 1996 |
Goodfellow HR, Sardini A, Ruetz S, Callaghan R, Gros P, McNaughton PA, Higgins CF. Protein kinase C-mediated phosphorylation does not regulate drug transport by the human multidrug resistance P-glycoprotein. The Journal of Biological Chemistry. 271: 13668-74. PMID 8662768 DOI: 10.1074/Jbc.271.23.13668 |
0.368 |
|
| 1995 |
Tame JR, Dodson EJ, Murshudov G, Higgins CF, Wilkinson AJ. The crystal structures of the oligopeptide-binding protein OppA complexed with tripeptide and tetrapeptide ligands Structure. 3: 1395-1406. PMID 8747465 DOI: 10.1016/S0969-2126(01)00276-3 |
0.303 |
|
| 1995 |
Higgins CF. Volume‐activated chloride currents associated with the multidrug resistance P‐glycoprotein. The Journal of Physiology. 482: 31-36. PMID 7730973 DOI: 10.1113/Jphysiol.1995.Sp020562 |
0.325 |
|
| 1995 |
Higgins CF. P-glycoprotein and cell volume-activated chloride channels Journal of Bioenergetics and Biomembranes. 27: 63-70. PMID 7543087 DOI: 10.1007/Bf02110332 |
0.337 |
|
| 1995 |
Hardy SP, Goodfellow HR, Valverde MA, Gill DR, Sepúlveda V, Higgins CF. Protein Kinase C-Mediated Phosphorylation Of The Human Multidrug Resistance P-Glycoprotein Regulates Cell Volume-Activated Chloride Channels The Embo Journal. 14: 68-75. DOI: 10.1002/J.1460-2075.1995.Tb06976.X |
0.332 |
|
| 1994 |
Tame JRH, Murshudov GN, Dodson EJ, Neil TK, Dodson GG, Higgins CF, Wilkinson AJ. The structural basis of sequence-independent peptide binding by OppA protein Science. 264: 1578-1581. PMID 8202710 DOI: 10.1126/Science.8202710 |
0.325 |
|
| 1994 |
Forsberg AJ, Pavitt GD, Higgins CF. Use of transcriptional fusions to monitor gene expression: a cautionary tale. Journal of Bacteriology. 176: 2128-2132. PMID 8144484 DOI: 10.1128/Jb.176.7.2128-2132.1994 |
0.329 |
|
| 1994 |
Higgins CF. P-Glycoprotein: To flip or not to flip? Current Biology. 4: 259-260. PMID 7857397 DOI: 10.1016/S0960-9822(00)00059-2 |
0.349 |
|
| 1994 |
Ussery DW, Hinton JC, Jordi BJ, Granum PE, Seirafi A, Stephen RJ, Tupper AE, Berridge G, Sidebotham JM, Higgins CF. The chromatin-associated protein H-NS. Biochimie. 76: 968-80. PMID 7748941 DOI: 10.1016/0300-9084(94)90022-1 |
0.312 |
|
| 1993 |
Mudd EA, Higgins CF. Escherichia coli endoribonuclease RNase E: autoregulation of expression and site-specific cleavage of mRNA. Molecular Microbiology. 9: 557-568. PMID 8412702 DOI: 10.1111/J.1365-2958.1993.Tb01716.X |
0.305 |
|
| 1993 |
Karlsson M, Hannavy K, Higgins CF. A sequence-specific function for the N-terminal signal-like sequence of the TonB protein. Molecular Microbiology. 8: 379-388. PMID 8316087 DOI: 10.1111/J.1365-2958.1993.Tb01581.X |
0.335 |
|
| 1993 |
Karlsson M, Hannavy K, Higgins CF. ExbB acts as a chaperone‐like protein to stabilize TonB in the cytoplasm Molecular Microbiology. 8: 389-396. PMID 8100348 DOI: 10.1111/J.1365-2958.1993.Tb01582.X |
0.343 |
|
| 1993 |
Higgins CF. The multidrug resistance P-glycoprotein Current Opinion in Cell Biology. 5: 684-687. PMID 7903042 DOI: 10.1016/0955-0674(93)90140-L |
0.35 |
|
| 1993 |
Hyde SC, Gill DR, Higgins CF, Trezise AE, MacVinish LJ, Cuthbert AW, Ratcliff R, Evans MJ, Colledge WH. Correction of the ion transport defect in cystic fibrosis transgenic mice by gene therapy. Nature. 362: 250-5. PMID 7681548 DOI: 10.1038/362250A0 |
0.319 |
|
| 1993 |
Higgins CF, Peltz SW, Jacobson A. Turnover of mRNA in prokaryotes and lower eukaryotes. Current Opinion in Genetics & Development. 2: 739-47. PMID 1281028 DOI: 10.1016/S0959-437X(05)80134-0 |
0.329 |
|
| 1992 |
Pearce SR, Mimmack ML, Gallagher MP, Gileadi U, Hyde SC, Higgins CF. Membrane topology of the integral membrane components, OppB and OppC, of the oligopeptide permease of Salmonella typhimurium Molecular Microbiology. 6: 47-57. PMID 1738314 DOI: 10.1111/J.1365-2958.1992.Tb00836.X |
0.406 |
|
| 1992 |
Owen-Hughes TA, Pavitt GD, Santos DS, Sidebotham JM, Hulton CS, Hinton JC, Higgins CF. The chromatin-associated protein H-NS interacts with curved DNA to influence DNA topology and gene expression. Cell. 71: 255-65. PMID 1423593 DOI: 10.1016/0092-8674(92)90354-F |
0.324 |
|
| 1992 |
Hinton JC, Santos DS, Seirafi A, Hulton CS, Pavitt GD, Higgins CF. Expression and mutational analysis of the nucleoid-associated protein H-NS of Salmonella typhimurium. Molecular Microbiology. 6: 2327-37. PMID 1406272 DOI: 10.1111/J.1365-2958.1992.Tb01408.X |
0.313 |
|
| 1992 |
Gill DR, Hyde SC, Higgins CF, Valverde MA, Mintenig GM, Sepúlveda FV. Separation of drug transport and chloride channel functions of the human multidrug resistance P-glycoprotein. Cell. 71: 23-32. PMID 1382860 DOI: 10.1016/0092-8674(92)90263-C |
0.379 |
|
| 1992 |
Higgins CF, Gottesman MM. Is the multidrug transporter a flippase? Trends in Biochemical Sciences. 17: 18-21. PMID 1374941 DOI: 10.1016/0968-0004(92)90419-A |
0.384 |
|
| 1992 |
Valverde MA, Díaz M, Sepúlveda FV, Gill DR, Hyde SC, Higgins CF. Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein. Nature. 355: 830-3. PMID 1371598 DOI: 10.1038/355830A0 |
0.411 |
|
| 1992 |
Tucker SJ, Tannahill D, Higgins CF. Identification and developmental expression of the Xenopus laevis cystic fibrosis transmembrane conductance regulator gene. Human Molecular Genetics. 1: 77-82. PMID 1284470 DOI: 10.1093/Hmg/1.2.77 |
0.55 |
|
| 1992 |
Higgins CF. ABC Transporters: From Microorganisms to Man Annual Review of Cell Biology. 8: 67-113. PMID 1282354 DOI: 10.1146/Annurev.Cb.08.110192.000435 |
0.424 |
|
| 1992 |
Higgins CF. Cystic fibrosis transmembrane conductance regulator (Cftr) British Medical Bulletin. 48: 754-764. PMID 1281034 DOI: 10.1093/Oxfordjournals.Bmb.A072576 |
0.313 |
|
| 1992 |
Trezise AEO, Romano PR, Gill DR, Hyde SC, Sepulveda FV, Buchwald M, Higgins CF. The multidrug resistance and cystic fibrosis genes have complementary patterns of epithelial expression. The Embo Journal. 11: 4291-4303. DOI: 10.1002/J.1460-2075.1992.Tb05528.X |
0.377 |
|
| 1991 |
Abouhamad WN, Manson M, Gibson MM, Higgins CF. Peptide transport and chemotaxis in Escherichia coli and Salmonella typhimurium: characterization of the dipeptide permease (Dpp) and the dipeptide-binding protein. Molecular Microbiology. 5: 1035-47. PMID 1956284 DOI: 10.1111/J.1365-2958.1991.Tb01876.X |
0.417 |
|
| 1991 |
Perego M, Higgins CF, Pearce SR, Gallagher MP, Hoch JA. The oligopeptide transport system of Bacillus subtilis plays a role in the initiation of sporulation Molecular Microbiology. 5: 173-185. PMID 1901616 DOI: 10.1111/J.1365-2958.1991.Tb01838.X |
0.366 |
|
| 1991 |
Lilley DMJ, Higgins CF. Local DNA topology and gene expression: the case of the leu-500 promoter. Molecular Microbiology. 5: 779-783. PMID 1857204 DOI: 10.1111/J.1365-2958.1991.Tb00749.X |
0.34 |
|
| 1991 |
Higgins CF. Stability and degradation of mRNA Current Opinion in Cell Biology. 3: 1013-1018. PMID 1814361 DOI: 10.1016/0955-0674(91)90122-F |
0.306 |
|
| 1991 |
Koo S, Higgins CF, Booth IR. Regulation of compatible solute accumulation in Salmonella typhimurium : evidence for a glycine betaine efflux system Microbiology. 137: 2617-2625. PMID 1783908 DOI: 10.1099/00221287-137-11-2617 |
0.376 |
|
| 1991 |
Crawford I, Maloney PC, Zeitlin PL, Guggino WB, Hyde SC, Turley H, Gatter KC, Harris A, Higgins CF. Immunocytochemical localization of the cystic fibrosis gene product CFTR Proceedings of the National Academy of Sciences of the United States of America. 88: 9262-9266. PMID 1718002 DOI: 10.1073/Pnas.88.20.9262 |
0.345 |
|
| 1990 |
Higgins CF. The role of ATP in binding-protein-dependent transport systems Research in Microbiology. 141: 353-360. PMID 2281193 DOI: 10.1016/0923-2508(90)90011-E |
0.388 |
|
| 1990 |
Hannavy K, Barr GC, Dorman CJ, Adamson J, Mazengera LR, Gallagher MP, Evans JS, Levine BA, Trayer IP, Higgins CF. TonB protein of Salmonella typhimurium. A model for signal transduction between membranes. Journal of Molecular Biology. 216: 897-910. PMID 2266561 DOI: 10.1016/S0022-2836(99)80009-6 |
0.361 |
|
| 1990 |
Brewer S, Tolley M, Trayer IP, Barr GC, Dorman CJ, Hannavy K, Higgins CF, Evans JS, Levine BA, Wormald MR. Structure and function of X-Pro dipeptide repeats in the TonB proteins of Salmonella typhimurium and Escherichia coli. Journal of Molecular Biology. 216: 883-95. PMID 2266560 DOI: 10.1016/S0022-2836(99)80008-4 |
0.347 |
|
| 1990 |
Higgins CF. DNA supercoiling, chromatin structure and the regulation of gene expression Antonie Van Leeuwenhoek. 58: 155. PMID 2256674 DOI: 10.1007/Bf00548926 |
0.347 |
|
| 1990 |
Higgins CF, Hyde SC, Mimmack MM, Gileadi U, Gill DR, Gallagher MP. Binding protein-dependent transport systems Journal of Bioenergetics and Biomembranes. 22: 571-592. PMID 2229036 DOI: 10.1007/Bf00762962 |
0.419 |
|
| 1990 |
Dorman CJ, Bhriain NN, Higgins CF. DNA supercoiling and environmental regulation of virulence gene expression in Shigella flexneri. Nature. 344: 789-792. PMID 2184366 DOI: 10.1038/344789A0 |
0.345 |
|
| 1990 |
Hulton CS, Seirafi A, Hinton JC, Sidebotham JM, Waddell L, Pavitt GD, Owen-Hughes T, Spassky A, Buc H, Higgins CF. Histone-like protein H1 (H-NS), DNA supercoiling, and gene expression in bacteria. Cell. 63: 631-42. PMID 2171779 DOI: 10.1016/0092-8674(90)90458-Q |
0.355 |
|
| 1990 |
Higgins CF, Hinton JC, Hulton CS, Owen-Hughes T, Pavitt GD, Seirafi A. Protein H1: a role for chromatin structure in the regulation of bacterial gene expression and virulence? Molecular Microbiology. 4: 2007-12. PMID 2128526 DOI: 10.1111/J.1365-2958.1990.Tb00559.X |
0.366 |
|
| 1990 |
Hyde SC, Emsley P, Hartshorn MJ, Mimmack MM, Gileadi U, Pearce SR, Gallagher MP, Gill DR, Hubbard RE, Higgins CF. Structural model of ATP-binding proteing associated with cystic fibrosis, multidrug resistance and bacterial transport Nature. 346: 362-365. PMID 1973824 DOI: 10.1038/346362A0 |
0.429 |
|
| 1990 |
Higgins CF, Gallagher MP, Hyde SC, Mimmack ML, Pearce SR. Periplasmic binding protein-dependent transport systems: the membrane-associated components Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 326: 353-364; discussion . PMID 1970642 DOI: 10.1098/Rstb.1990.0017 |
0.405 |
|
| 1989 |
Higgins C. Cystic fibrosis: protein joins transport family Nature. 341: 103. PMID 2779645 DOI: 10.1038/341103A0 |
0.343 |
|
| 1989 |
Stirling DA, Hulton CSJ, Waddell L, Park SF, Stewart GSAB, Booth IR, Higgins CF. Molecular characterization of the proU loci of Salmonella typhimurium and Escherichia coli encoding osmoregulated glycine betaine transport systems. Molecular Microbiology. 3: 1025-1038. PMID 2691838 DOI: 10.1111/J.1365-2958.1989.Tb00253.X |
0.461 |
|
| 1989 |
Park SF, Stirling DA, Hulton CSJ, Booth IR, Higgins CF, Stewart GSAB. A novel, non-invasive promoter probe vector: cloning of the osmoregulated proU promoter of Escherichia coli K12 Molecular Microbiology. 3: 1011-1023. PMID 2691837 DOI: 10.1111/J.1365-2958.1989.Tb00252.X |
0.314 |
|
| 1989 |
Mimmack ML, Gallagher MP, Pearce SR, Hyde SC, Booth IR, Higgins CF. Energy coupling to periplasmic binding protein-dependent transport systems: Stoichiometry of ATP hydrolysis during transport in vivo Proceedings of the National Academy of Sciences of the United States of America. 86: 8257-8261. PMID 2682642 DOI: 10.1073/Pnas.86.21.8257 |
0.387 |
|
| 1989 |
Bhriain NN, Dorman CJ, Higgins CF. An overlap between osmotic and anaerobic stress responses: a potential role for DNA supercoiling in the coordinate regulation of gene expression Molecular Microbiology. 3: 933-942. PMID 2677605 DOI: 10.1111/J.1365-2958.1989.Tb00243.X |
0.356 |
|
| 1989 |
Higgins C. Transport proteins. Export-import family expands Nature. 340: 342. PMID 2569165 DOI: 10.1038/340342A0 |
0.348 |
|
| 1989 |
Graeme-Cook KA, May G, Bremer E, Higgins CF. Osmotic regulation of porin expression: a role for DNA supercoiling Molecular Microbiology. 3: 1287-1294. PMID 2552265 DOI: 10.1111/J.1365-2958.1989.Tb00279.X |
0.359 |
|
| 1989 |
Dorman CJ, Lynch AS, Bhriain NN, Higgins CF. DNA supercoiling in Escherichia coli: topA mutations can be suppressed by DNA amplifications involving the tolC locus. Molecular Microbiology. 3: 531-540. PMID 2548062 DOI: 10.1111/J.1365-2958.1989.Tb00199.X |
0.311 |
|
| 1988 |
Higgins CF, Gallagher MP, Mimmack ML, Pearce SR. A family of closely related ATP-binding subunits from prokaryotic and eukaryotic cells Bioessays. 8: 111-116. PMID 3288195 DOI: 10.1002/Bies.950080406 |
0.403 |
|
| 1988 |
Higgins CF, McLaren RS, Newbury SF. Repetitive extragenic palindromic sequences, mRNA stability and gene expression: evolution by gene conversion? A review. Gene. 72: 3-14. PMID 3072249 DOI: 10.1016/0378-1119(88)90122-9 |
0.334 |
|
| 1988 |
Dorman CJ, Barr GC, Bhriain NN, Higgins CF. DNA supercoiling and the anaerobic and growth phase regulation of tonB gene expression. Journal of Bacteriology. 170: 2816-2826. PMID 2836373 DOI: 10.1128/Jb.170.6.2816-2826.1988 |
0.329 |
|
| 1988 |
Higgins CF, Dorman CJ, Stirling DA, Waddell L, Booth IR, May G, Bremer E. A physiological role for DNA supercoiling in the osmotic regulation of gene expression in S. typhimurium and E. coli Cell. 52: 569-584. PMID 2830029 DOI: 10.1016/0092-8674(88)90470-9 |
0.353 |
|
| 1988 |
Richardson SM, Higgins CF, Lilley DM. DNA supercoiling and the leu-500 promoter mutation of Salmonella typhimurium. The Embo Journal. 7: 1863-1869. DOI: 10.1002/J.1460-2075.1988.Tb03019.X |
0.312 |
|
| 1987 |
Higgins CF, Sutherland L, Cairney J, Booth IR. The osmotically regulated proU locus of Salmonella typhimurium encodes a periplasmic betaine-binding protein. Microbiology. 133: 305-310. PMID 3309148 DOI: 10.1099/00221287-133-2-305 |
0.401 |
|
| 1987 |
Gibson MM, Ellis EM, Graeme-Cook KA, Higgins CF. OmpR and EnvZ are pleiotropic regulatory proteins: positive regulation of the tripeptide permease (tppB) of Salmonella typhimurium. Molecular & General Genetics : Mgg. 207: 120-9. PMID 3037276 DOI: 10.1007/Bf00331499 |
0.378 |
|
| 1987 |
Hiles ID, Powell LM, Higgins CF. Peptide transport in Salmonella typhimurium: Molecular cloning and characterization of the oligopeptide permease genes Mgg Molecular &Amp; General Genetics. 206: 101-109. PMID 3033433 DOI: 10.1007/Bf00326543 |
0.351 |
|
| 1987 |
Dorman CJ, Higgins CF. Fimbrial phase variation in Escherichia coli: Dependence on integration host factor and homologies with other site-specific recombinases Journal of Bacteriology. 169: 3840-3843. PMID 2886490 DOI: 10.1128/Jb.169.8.3840-3843.1987 |
0.301 |
|
| 1987 |
Hiles ID, Gallagher MP, Jamieson DJ, Higgins CF. Molecular characterization of the oligopeptide permease of Salmonella typhimurium Journal of Molecular Biology. 195: 125-142. PMID 2821267 DOI: 10.1016/0022-2836(87)90332-9 |
0.458 |
|
| 1987 |
Newbury SF, Smith NH, Higgins CF. Differential mRNA stability controls relative gene expression within a polycistronic operon Cell. 51: 1131-1143. PMID 2446776 DOI: 10.1016/0092-8674(87)90599-X |
0.33 |
|
| 1987 |
Newbury SF, Smith NH, Robinson EC, Hiles ID, Higgins CF. Stabilization of translationally active mRNA by prokaryotic REP sequences. Cell. 48: 297-310. PMID 2433046 DOI: 10.1016/0092-8674(87)90433-8 |
0.333 |
|
| 1987 |
Higgins CF, Cairney J, Stirling DA, Sutherland L, Booth IR. Osmotic regulation of gene expression: ionic strength as an intracellular signal? Trends in Biochemical Sciences. 12: 339-344. DOI: 10.1016/0968-0004(87)90158-7 |
0.384 |
|
| 1986 |
Higgins CF, Hiles ID, Salmond GPC, Gill DR, Downie JA, Evans IJ, Holland IB, Gray L, Buckel SD, Bell AW, Hermodson MA. A family of related ATP-binding subunits coupled to many distinct biological processes in bacteria. Nature. 323: 448-450. PMID 3762694 DOI: 10.1038/323448A0 |
0.364 |
|
| 1986 |
Sutherland L, Cairney J, Elmore MJ, Booth IR, Higgins CF. Osmotic regulation of transcription: induction of the proU betaine transport gene is dependent on accumulation of intracellular potassium. Journal of Bacteriology. 168: 805-814. PMID 3536861 DOI: 10.1128/Jb.168.2.805-814.1986 |
0.414 |
|
| 1986 |
Hiles ID, Higgins CF. Peptide uptake by Salmonella typhimurium. The periplasmic oligopeptide-binding protein. Febs Journal. 158: 561-567. PMID 3525163 DOI: 10.1111/J.1432-1033.1986.Tb09791.X |
0.36 |
|
| 1986 |
Manson MD, Blank V, Brade G, Higgins CF. Peptide chemotaxis in E. coli involves the Tap signal transducer and the dipeptide permease Nature. 321: 253-256. PMID 3520334 DOI: 10.1038/321253A0 |
0.32 |
|
| 1986 |
Evans JS, Levine BA, Trayer IP, Dorman CJ, Higgins CF. Sequence-imposed structural constraints in the TonB protein of E. coli. Febs Letters. 208: 211-6. PMID 3023135 DOI: 10.1016/0014-5793(86)81020-1 |
0.374 |
|
| 1986 |
Brass JM, Higgins CF, Foley M, Rugman PA, Birmingham J, Garland PB. Lateral diffusion of proteins in the periplasm of Escherichia coli. Journal of Bacteriology. 165: 787-95. PMID 3005237 DOI: 10.1128/Jb.165.3.787-795.1986 |
0.305 |
|
| 1985 |
Cairney J, Booth IR, Higgins CF. Osmoregulation of gene expression in Salmonella typhimurium: proU encodes an osmotically induced betaine transport system. Journal of Bacteriology. 164: 1224-1232. PMID 3905768 DOI: 10.1128/Jb.164.3.1224-1232.1985 |
0.415 |
|
| 1985 |
Cairney J, Booth IR, Higgins CF. Salmonella typhimurium proP gene encodes a transport system for the osmoprotectant betaine. Journal of Bacteriology. 164: 1218-1223. PMID 3905767 DOI: 10.1128/Jb.164.3.1218-1223.1985 |
0.397 |
|
| 1985 |
Higgins CF, Hiles ID, Whalley K, Jamieson DJ. Nucleotide binding by membrane components of bacterial periplasmic binding protein-dependent transport systems. The Embo Journal. 4: 1033-1039. DOI: 10.1002/J.1460-2075.1985.Tb03735.X |
0.401 |
|
| 1984 |
Stern MJ, Ames GF, Smith NH, Robinson EC, Higgins CF. Repetitive extragenic palindromic sequences: a major component of the bacterial genome. Cell. 37: 1015-26. PMID 6378385 DOI: 10.1016/0092-8674(84)90436-7 |
0.624 |
|
| 1984 |
Higgins CF. Molecular mechanisms of bacterial periplasmic transport systems Biochemical Society Transactions. 12: 232-233. PMID 6373438 DOI: 10.1042/Bst0120232 |
0.332 |
|
| 1984 |
Stern MJ, Higgins CF, Ames GF. Isolation and characterization of lac fusions to two nitrogen-regulated promoters. Molecular & General Genetics : Mgg. 195: 219-27. PMID 6092849 DOI: 10.1007/Bf00332750 |
0.641 |
|
| 1984 |
Cairney J, Higgins CF, Booth IR. Proline uptake through the major transport system of Salmonella typhimurium is coupled to sodium ions. Journal of Bacteriology. 160: 22-27. PMID 6090414 DOI: 10.1128/Jb.160.1.22-27.1984 |
0.328 |
|
| 1984 |
Richardson S, Higgins C, Lilley D. The genetic control of DNA supercoiling in Salmonella typhimurium. The Embo Journal. 3: 1745-1752. DOI: 10.1002/J.1460-2075.1984.Tb02041.X |
0.317 |
|
| 1983 |
Hogarth BG, Higgins CF. Genetic organization of the oligopeptide permease (opp) locus of Salmonella typhimurium and Escherichia coli. Journal of Bacteriology. 153: 1548-51. PMID 6338001 DOI: 10.1128/Jb.153.3.1548-1551.1983 |
0.315 |
|
| 1983 |
Ames GF, Higgins CF. The organization, mechanism of action, and evolution of periplasmic transport systems Trends in Biochemical Sciences. 8: 97-100. DOI: 10.1016/0968-0004(83)90259-1 |
0.639 |
|
| 1982 |
Higgins CF, Haag PD, Nikaido K, Ardeshir F, Garcia G, Ames GF. Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium Nature. 298: 723-727. PMID 7050725 DOI: 10.1038/298723a0 |
0.653 |
|
| 1982 |
Gilson E, Higgins CF, Hofnung M, Ferro-Luzzi Ames G, Nikaido H. Extensive homology between membrane-associated components of histidine and maltose transport systems of Salmonella typhimurium and Escherichia coli Journal of Biological Chemistry. 257: 9915-9918. PMID 7050111 |
0.324 |
|
| 1982 |
Higgins CF, Ames GF. Regulatory regions of two transport operons under nitrogen control: nucleotide sequences. Proceedings of the National Academy of Sciences of the United States of America. 79: 1083-7. PMID 7041112 DOI: 10.1073/pnas.79.4.1083 |
0.651 |
|
| 1981 |
Higgins CF, Ames GF. Two periplasmic transport proteins which interact with a common membrane receptor show extensive homology: complete nucleotide sequences. Proceedings of the National Academy of Sciences of the United States of America. 78: 6038-42. PMID 6273842 DOI: 10.1073/Pnas.78.10.6038 |
0.669 |
|
| 1981 |
Ardeshir F, Higgins CF, Ames GF. Physical map of the Salmonella typhimurium histidine transport operon: correlation with the genetic map. Journal of Bacteriology. 147: 401-9. PMID 6267009 DOI: 10.1128/Jb.147.2.401-409.1981 |
0.606 |
|
| 1978 |
Higgins CF, Payne JW. Peptide transport by germinating barley embryos: Evidence for a single common carrier for di- and oligopeptides. Planta. 138: 217-21. PMID 24414049 DOI: 10.1007/Bf00386814 |
0.306 |
|
| 1978 |
Higgins CF, Payne JW. Peptide transport by germinating barley embryos: Uptake of physiological di- and oligopeptides. Planta. 138: 211-5. PMID 24414048 DOI: 10.1007/Bf00386813 |
0.325 |
|
| 1978 |
Higgins CF, Payne JW. Stereospecificity of peptide transport by germinating barley embryos. Planta. 142: 299-305. PMID 24408193 DOI: 10.1007/Bf00385081 |
0.315 |
|
| 1977 |
Higgins CF, Payne JW. Characterization of active dipeptide transport by germinating barley embryos: Effects of pH and metabolic inhibitors. Planta. 136: 71-6. PMID 24420230 DOI: 10.1007/Bf00387928 |
0.329 |
|
| 1977 |
Higgins CF, Payne JW. Peptide transport by germinating barley embryos. Planta. 134: 205-6. PMID 24419702 DOI: 10.1007/Bf00384973 |
0.334 |
|
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