Year |
Citation |
Score |
2016 |
Tweedie D, Fukui K, Li Y, Yu QS, Barak S, Tamargo IA, Rubovitch V, Holloway HW, Lehrmann E, Wood WH, Zhang Y, Becker KG, Perez E, Van Praag H, Luo Y, et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. Plos One. 11: e0156493. PMID 27254111 DOI: 10.1371/Journal.Pone.0156493 |
0.379 |
|
2014 |
Zhu M, Allard JS, Zhang Y, Perez E, Spangler EL, Becker KG, Rapp PR. Age-related brain expression and regulation of the chemokine CCL4/MIP-1β in APP/PS1 double-transgenic mice. Journal of Neuropathology and Experimental Neurology. 73: 362-74. PMID 24607962 DOI: 10.1097/Nen.0000000000000060 |
0.312 |
|
2013 |
Tweedie D, Rachmany L, Rubovitch V, Lehrmann E, Zhang Y, Becker KG, Perez E, Miller J, Hoffer BJ, Greig NH, Pick CG. Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice. Experimental Neurology. 239: 170-82. PMID 23059457 DOI: 10.1016/J.Expneurol.2012.10.001 |
0.348 |
|
2013 |
Simpkins JW, Richardson TE, Yi KD, Perez E, Covey DF. Neuroprotection with non-feminizing estrogen analogues: an overlooked possible therapeutic strategy. Hormones and Behavior. 63: 278-83. PMID 22498694 DOI: 10.1016/J.Yhbeh.2012.03.013 |
0.81 |
|
2012 |
Luedtke RR, Perez E, Yang SH, Liu R, Vangveravong S, Tu Z, Mach RH, Simpkins JW. Neuroprotective effects of high affinity Σ1 receptor selective compounds. Brain Research. 1441: 17-26. PMID 22285434 DOI: 10.1016/J.Brainres.2011.12.047 |
0.75 |
|
2011 |
Yi KD, Perez E, Yang S, Liu R, Covey DF, Simpkins JW. The assessment of non-feminizing estrogens for use in neuroprotection. Brain Research. 1379: 61-70. PMID 21111714 DOI: 10.1016/J.Brainres.2010.11.058 |
0.793 |
|
2009 |
Simpkins JW, Perez E, Wang X, Yang S, Wen Y, Singh M. The potential for estrogens in preventing Alzheimer's disease and vascular dementia. Therapeutic Advances in Neurological Disorders. 2: 31-49. PMID 19890493 DOI: 10.1177/1756285608100427 |
0.782 |
|
2009 |
Yang SH, Sarkar SN, Liu R, Perez EJ, Wang X, Wen Y, Yan LJ, Simpkins JW. Estrogen receptor beta as a mitochondrial vulnerability factor. The Journal of Biological Chemistry. 284: 9540-8. PMID 19189968 DOI: 10.1074/Jbc.M808246200 |
0.759 |
|
2007 |
Schetz JA, Perez E, Liu R, Chen S, Lee I, Simpkins JW. A prototypical Sigma-1 receptor antagonist protects against brain ischemia. Brain Research. 1181: 1-9. PMID 17919467 DOI: 10.1016/J.Brainres.2007.08.068 |
0.669 |
|
2007 |
Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr VA, Rosenzweig A, de Cabo R, Sauve AA, Sinclair DA. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell. 130: 1095-107. PMID 17889652 DOI: 10.1016/J.Cell.2007.07.035 |
0.329 |
|
2007 |
Wang X, Perez E, Liu R, Yan L, Mallet RT, Yang S. Pyruvate protects mitochondria from oxidative stress in human neuroblastoma SK-N-SH cells. Brain Research. 1132: 1-9. PMID 17174285 DOI: 10.1016/J.Brainres.2006.11.032 |
0.738 |
|
2007 |
Wen Y, Yang SH, Liu R, Perez EJ, Brun-Zinkernagel AM, Koulen P, Simpkins JW. Cdk5 is involved in NFT-like tauopathy induced by transient cerebral ischemia in female rats. Biochimica Et Biophysica Acta. 1772: 473-83. PMID 17113760 DOI: 10.1016/J.Bbadis.2006.10.011 |
0.755 |
|
2007 |
Perez E, Wang X, Simpkins JW. Role of antioxidant activity of estrogens in their potent neuroprotection Oxidative Stress and Neurodegenerative Disorders. 503-524. DOI: 10.1016/B978-044452809-4/50163-0 |
0.6 |
|
2006 |
Wang X, Dykens JA, Perez E, Liu R, Yang S, Covey DF, Simpkins JW. Neuroprotective effects of 17beta-estradiol and nonfeminizing estrogens against H2O2 toxicity in human neuroblastoma SK-N-SH cells. Molecular Pharmacology. 70: 395-404. PMID 16614138 DOI: 10.1124/Mol.106.022384 |
0.784 |
|
2005 |
Liu R, Wen Y, Perez E, Wang X, Day AL, Simpkins JW, Yang SH. 17beta-Estradiol attenuates blood-brain barrier disruption induced by cerebral ischemia-reperfusion injury in female rats. Brain Research. 1060: 55-61. PMID 16212944 DOI: 10.1016/J.Brainres.2005.08.048 |
0.787 |
|
2005 |
Simpkins JW, Wen Y, Perez E, Yang S, Wang X. Role of nonfeminizing estrogens in brain protection from cerebral ischemia: an animal model of Alzheimer's disease neuropathology. Annals of the New York Academy of Sciences. 1052: 233-42. PMID 16024766 DOI: 10.1196/Annals.1347.019 |
0.804 |
|
2005 |
Yang SH, Liu R, Perez EJ, Wang X, Simpkins JW. Estrogens as protectants of the neurovascular unit against ischemic stroke. Current Drug Targets. Cns and Neurological Disorders. 4: 169-77. PMID 15857302 DOI: 10.2174/1568007053544174 |
0.778 |
|
2005 |
Kumar DM, Perez E, Cai ZY, Aoun P, Brun-Zinkernagel AM, Covey DF, Simpkins JW, Agarwal N. Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity. Free Radical Biology & Medicine. 38: 1152-63. PMID 15808412 DOI: 10.1016/J.Freeradbiomed.2004.12.007 |
0.803 |
|
2005 |
Perez E, Liu R, Yang SH, Cai ZY, Covey DF, Simpkins JW. Neuroprotective effects of an estratriene analog are estrogen receptor independent in vitro and in vivo. Brain Research. 1038: 216-22. PMID 15757637 DOI: 10.1016/J.Brainres.2005.01.026 |
0.805 |
|
2005 |
Simpkins JW, Wang J, Wang X, Perez E, Prokai L, Dykens JA. Mitochondria play a central role in estrogen-induced neuroprotection. Current Drug Targets. Cns and Neurological Disorders. 4: 69-83. PMID 15723615 DOI: 10.2174/1568007053005073 |
0.648 |
|
2005 |
Yang SH, Liu R, Wen Y, Perez E, Cutright J, Brun-Zinkernagel AM, Singh M, Day AL, Simpkins JW. Neuroendocrine mechanism for tolerance to cerebral ischemia-reperfusion injury in male rats. Journal of Neurobiology. 62: 341-51. PMID 15514992 DOI: 10.1002/Neu.20103 |
0.785 |
|
2005 |
Kumar DM, Perez E, Cai ZY, Aoun P, Brun-Zinkernagel A, Covey DF, Simpkins JW, Agarwal N. Corrigendum to “Role of nonfeminizing estrogen analogues in neuroprotection of rat retinal ganglion cells against glutamate-induced cytotoxicity” [Free Radic. Biol. Med. 38:1152–1163; 2005] Free Radical Biology and Medicine. 39: 1676. DOI: 10.1016/J.Freeradbiomed.2005.09.009 |
0.767 |
|
2005 |
Perez E, Cai ZY, Covey DF, Simpkins JW. Neuroprotective effects of estratriene analogs: Structure-activity relationships and molecular optimization Drug Development Research. 66: 78-92. DOI: 10.1002/Ddr.20047 |
0.586 |
|
2004 |
Jung ME, Rewal M, Perez E, Wen Y, Simpkins JW. Estrogen protects against brain lipid peroxidation in ethanol-withdrawn rats. Pharmacology, Biochemistry, and Behavior. 79: 573-86. PMID 15582030 DOI: 10.1016/J.Pbb.2004.09.007 |
0.734 |
|
2004 |
Simpkins JW, Yang SH, Liu R, Perez E, Cai ZY, Covey DF, Green PS. Estrogen-like compounds for ischemic neuroprotection. Stroke; a Journal of Cerebral Circulation. 35: 2648-51. PMID 15472107 DOI: 10.1161/01.Str.0000143734.59507.88 |
0.819 |
|
2004 |
Wen Y, Perez EJ, Green PS, Sarkar SN, Simpkins JW. nNOS is involved in estrogen mediated neuroprotection in neuroblastoma cells. Neuroreport. 15: 1515-8. PMID 15194886 DOI: 10.1097/01.Wnr.0000131674.92694.96 |
0.798 |
|
2004 |
Wen Y, Yang S, Liu R, Perez E, Yi KD, Koulen P, Simpkins JW. Estrogen attenuates nuclear factor-kappa B activation induced by transient cerebral ischemia. Brain Research. 1008: 147-54. PMID 15145751 DOI: 10.1016/J.Brainres.2004.02.019 |
0.796 |
|
2004 |
Yang SH, Liu R, Perez EJ, Wen Y, Stevens SM, Valencia T, Brun-Zinkernagel AM, Prokai L, Will Y, Dykens J, Koulen P, Simpkins JW. Mitochondrial localization of estrogen receptor beta. Proceedings of the National Academy of Sciences of the United States of America. 101: 4130-5. PMID 15024130 DOI: 10.1073/Pnas.0306948101 |
0.769 |
|
2003 |
Prokai L, Prokai-Tatrai K, Perjesi P, Zharikova AD, Perez EJ, Liu R, Simpkins JW. Quinol-based cyclic antioxidant mechanism in estrogen neuroprotection. Proceedings of the National Academy of Sciences of the United States of America. 100: 11741-6. PMID 14504383 DOI: 10.1073/Pnas.2032621100 |
0.647 |
|
2002 |
Liu R, Yang SH, Perez E, Yi KD, Wu SS, Eberst K, Prokai L, Prokai-Tatrai K, Cai ZY, Covey DF, Day AL, Simpkins JW. Neuroprotective effects of a novel non-receptor-binding estrogen analogue: in vitro and in vivo analysis. Stroke; a Journal of Cerebral Circulation. 33: 2485-91. PMID 12364742 DOI: 10.1161/01.Str.0000030317.43597.C8 |
0.811 |
|
2002 |
Yang SH, Perez E, Cutright J, Liu R, He Z, Day AL, Simpkins JW. Testosterone increases neurotoxicity of glutamate in vitro and ischemia-reperfusion injury in an animal model. Journal of Applied Physiology (Bethesda, Md. : 1985). 92: 195-201. PMID 11744660 DOI: 10.1152/Jappl.2002.92.1.195 |
0.781 |
|
2000 |
Green PS, Perez EJ, Calloway T, Simpkins JW. Estradiol attenuation of beta-amyloid-induced toxicity: a comparison o. Journal of Neurocytology. 29: 419-23. PMID 11424958 DOI: 10.1023/A:1007173509470 |
0.705 |
|
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