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Barry J. Hoffer - Publications

Affiliations: 
National Institute on Drug Abuse 
Area:
Pharmacology
Website:
http://www.drugabuse.gov/DIR/cell-neuro.html

310 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Chen YH, Wu KJ, Hsieh W, Harvey BK, Hoffer BJ, Wang Y, Yu SJ. Administration of AAV-Alpha Synuclein NAC Antibody Improves Locomotor Behavior in Rats Overexpressing Alpha Synuclein. Genes. 12. PMID 34205689 DOI: 10.3390/genes12060948  0.725
2021 Wang V, Kuo TT, Huang EY, Ma KH, Chou YC, Fu ZY, Lai LW, Jung J, Choi HI, Choi DS, Li Y, Olson L, Greig NH, Hoffer BJ, Chen YH. Sustained Release GLP-1 Agonist PT320 Delays Disease Progression in a Mouse Model of Parkinson's Disease. Acs Pharmacology & Translational Science. 4: 858-869. PMID 33860208 DOI: 10.1021/acsptsci.1c00013  0.524
2020 Yu SJ, Chen S, Yang YY, Glotfelty EJ, Jung J, Kim HK, Choi HI, Choi DS, Hoffer BJ, Greig NH, Wang Y. PT320, Sustained-Release Exendin-4, Mitigates L-DOPA-Induced Dyskinesia in a Rat 6-Hydroxydopamine Model of Parkinson's Disease. Frontiers in Neuroscience. 14: 785. PMID 32848559 DOI: 10.3389/Fnins.2020.00785  0.304
2020 Tweedie D, Karnati HK, Mullins R, Pick CG, Hoffer BJ, Goetzl EJ, Kapogiannis D, Greig NH. Time-dependent cytokine and chemokine changes in mouse cerebral cortex following a mild traumatic brain injury. Elife. 9. PMID 32804078 DOI: 10.7554/eLife.55827  0.305
2020 Lin CT, Lecca D, Yang LY, Luo W, Scerba MT, Tweedie D, Huang PS, Jung YJ, Kim DS, Yang CH, Hoffer BJ, Wang JY, Greig NH. 3,6'-Dithiopomalidomide reduces neural loss, inflammation, behavioral deficits in brain injury and microglial activation. Elife. 9. PMID 32589144 DOI: 10.7554/eLife.54726  0.318
2020 Chen YH, Yu SJ, Wu KJ, Wang YS, Tsai HM, Liao LW, Chen S, Hsieh W, Chen H, Hsu SC, Chen ML, Hoffer BJ, Wang Y. Downregulation of α-Synuclein Protein Levels by an Intracellular Single-Chain Antibody. Journal of Parkinson's Disease. PMID 32176654 DOI: 10.3233/JPD-191787  0.325
2019 Chen YH, Wang V, Huang EY, Chou YC, Kuo TT, Olson L, Hoffer BJ. Delayed Dopamine Dysfunction and Motor Deficits in Female Parkinson Model Mice. International Journal of Molecular Sciences. 20. PMID 31835787 DOI: 10.3390/ijms20246251  0.575
2019 Yang LY, Greig NH, Tweedie D, Jung YJ, Chiang YH, Hoffer BJ, Miller JP, Chang KH, Wang JY. The p53 inactivators pifithrin-μ and pifithrin-α mitigate TBI-induced neuronal damage through regulation of oxidative stress, neuroinflammation, autophagy and mitophagy. Experimental Neurology. 113135. PMID 31778663 DOI: 10.1016/j.expneurol.2019.113135  0.318
2019 Li Y, Glotfelty EJ, Namdar I, Tweedie D, Olson L, Hoffer BJ, DiMarchi RD, Pick CG, Greig NH. Neurotrophic and neuroprotective effects of a monomeric GLP-1/GIP/Gcg receptor triagonist in cellular and rodent models of mild traumatic brain injury. Experimental Neurology. 113113. PMID 31730763 DOI: 10.1016/J.Expneurol.2019.113113  0.57
2019 Glotfelty EJ, Delgado T, Tovar-Y-Romo LB, Luo Y, Hoffer B, Olson L, Karlsson T, Mattson MP, Harvey B, Tweedie D, Li Y, Greig NH. Incretin Mimetics as Rational Candidates for the Treatment of Traumatic Brain Injury. Acs Pharmacology & Translational Science. 2: 66-91. PMID 31396586 DOI: 10.1021/acsptsci.9b00003  0.657
2019 Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH. (-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice. Neurobiology of Disease. 104528. PMID 31295555 DOI: 10.1016/J.Nbd.2019.104528  0.736
2019 Lai JH, Chen KY, Chung-Che Wu J, Olson L, Brené S, Huang CZ, Chen YH, Kang SJ, Ma KH, Hoffer BJ, Hsieh TH, Chiang YH. Voluntary exercise delays progressive deterioration of markers of metabolism and behavior in a mouse model of Parkinson's disease. Brain Research. 146301. PMID 31226324 DOI: 10.1016/j.brainres.2019.146301  0.562
2019 Hsueh SC, Lecca D, Greig NH, Wang JY, Selman W, Hoffer BJ, Miller JP, Chiang YH. (-)-Phenserine Ameliorates Contusion Volume, Neuroinflammation, and Behavioral Impairments Induced by Traumatic Brain Injury in Mice. Cell Transplantation. 963689719854693. PMID 31177840 DOI: 10.1177/0963689719854693  0.304
2019 Hartman JH, Richie CT, Gordon KL, Mello DF, Castillo P, Zhu A, Wang Y, Hoffer BJ, Sherwood DR, Meyer JN, Harvey BK. MANF deletion abrogates early larval Caenorhabditis elegans stress response to tunicamycin and Pseudomonas aeruginosa. European Journal of Cell Biology. PMID 31138438 DOI: 10.1016/J.Ejcb.2019.05.002  0.572
2019 Chen YH, Hsieh TH, Kuo TT, Kao JH, Ma KH, Huang EY, Chou YC, Olson L, Hoffer BJ. Release parameters during progressive degeneration of dopamine neurons in mouse model reveal earlier impairment of spontaneous than forced behaviors. Journal of Neurochemistry. PMID 30933310 DOI: 10.1111/jnc.14702  0.593
2019 Batsaikhan B, Wang JY, Scerba MT, Tweedie D, Greig NH, Miller JP, Hoffer BJ, Lin CT, Wang JY. Post-Injury Neuroprotective Effects of the Thalidomide Analog 3,6'-Dithiothalidomide on Traumatic Brain Injury. International Journal of Molecular Sciences. 20. PMID 30682785 DOI: 10.3390/ijms20030502  0.344
2018 Bader M, Li Y, Lecca D, Rubovitch V, Tweedie D, Glotfelty E, Rachmany L, Kim HK, Choi HI, Hoffer BJ, Pick CG, Greig NH, Kim DS. Pharmacokinetics and efficacy of PT302, a sustained-release Exenatide formulation, in a murine model of mild traumatic brain injury. Neurobiology of Disease. PMID 30471415 DOI: 10.1016/J.Nbd.2018.11.023  0.315
2018 Tsai YR, Chang CF, Lai JH, Wu JC, Chen YH, Kang SJ, Hoffer BJ, Tweedie D, Luo W, Greig NH, Chiang YH, Chen KY. Pomalidomide Ameliorates H₂O₂-Induced Oxidative Stress Injury and Cell Death in Rat Primary Cortical Neuronal Cultures by Inducing Anti-Oxidative and Anti-Apoptosis Effects. International Journal of Molecular Sciences. 19. PMID 30347766 DOI: 10.3390/ijms19103252  0.324
2018 Lai JH, Karlsson TE, Wu JC, Huang CZ, Chen YH, Kang SJ, Brodin ATS, Hoffer BJ, Olson L, Chiang YH, Chen KY. Role of Nogo receptor-1 for recovery of balance, cognition and emotion after mild traumatic brain injury in mice. Journal of Neurotrauma. PMID 30226403 DOI: 10.1089/Neu.2018.5949  0.55
2018 Chen S, Yu SJ, Li Y, Lecca D, Glotfelty E, Kim HK, Choi HI, Hoffer BJ, Greig NH, Kim DS, Wang Y. Post-treatment with PT302, a long-acting Exendin-4 sustained release formulation, reduces dopaminergic neurodegeneration in a 6-Hydroxydopamine rat model of Parkinson's disease. Scientific Reports. 8: 10722. PMID 30013201 DOI: 10.1038/S41598-018-28449-Z  0.356
2018 Yuan-Hao C, Kuo TT, Huang EY, Hoffer BJ, Kao JH, Chou YC, Chiang YH, Miller J. Nicotine-induced Conditional Place Preference is Affected by Head Injury: Correlation with Dopamine Release in the Nucleus Accumbens Shell. The International Journal of Neuropsychopharmacology. PMID 29905798 DOI: 10.1093/ijnp/pyy055  0.319
2018 Chen YH, Lin BJ, Hsieh TH, Kuo TT, Miller J, Chou YC, Huang EY, Hoffer BJ. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell Transplantation. 963689718775382. PMID 29807460 DOI: 10.1177/0963689718775382  0.327
2018 Yu YW, Hsueh SC, Lai JH, Chen YH, Kang SJ, Chen KY, Hsieh TH, Hoffer BJ, Li Y, Greig NH, Chiang YH. Glucose-Dependent Insulinotropic Polypeptide Mitigates 6-OHDA-Induced Behavioral Impairments in Parkinsonian Rats. International Journal of Molecular Sciences. 19. PMID 29641447 DOI: 10.3390/ijms19041153  0.336
2018 Chen YH, Kuo TT, Yi-Kung Huang E, Chou YC, Chiang YH, Hoffer BJ, Miller J. Effect of traumatic brain injury on nicotine-induced modulation of dopamine release in the striatum and nucleus accumbens shell. Oncotarget. 9: 10016-10028. PMID 29515787 DOI: 10.18632/oncotarget.24245  0.314
2018 Chen YH, Kuo TT, Kao JH, Huang EY, Hsieh TH, Chou YC, Hoffer BJ. Exercise Ameliorates Motor Deficits and Improves Dopaminergic Functions in the Rat Hemi-Parkinson's Model. Scientific Reports. 8: 3973. PMID 29507426 DOI: 10.1038/s41598-018-22462-y  0.324
2017 Kim DS, Choi HI, Wang Y, Luo Y, Hoffer BJ, Greig NH. A New Treatment Strategy for Parkinson's Disease through the Gut-Brain Axis: The Glucagon-Like Peptide-1 Receptor Pathway. Cell Transplantation. 26: 1560-1571. PMID 29113464 DOI: 10.1177/0963689717721234  0.301
2017 Chen YH, Huang EY, Kuo TT, Miller J, Chiang YH, Hoffer BJ. Impact of Traumatic Brain Injury on Dopaminergic Transmission. Cell Transplantation. 26: 1156-1168. PMID 28933212 DOI: 10.1177/0963689717714105  0.34
2017 Rachmany L, Tweedie D, Rubovitch V, Li Y, Holloway HW, Kim DS, Ratliff WA, Saykally JN, Citron BA, Hoffer BJ, Greig NH, Pick CG. Exendin-4 attenuates blast traumatic brain injury induced cognitive impairments, losses of synaptophysin and in vitro TBI-induced hippocampal cellular degeneration. Scientific Reports. 7: 3735. PMID 28623327 DOI: 10.1038/s41598-017-03792-9  0.304
2017 Chen YH, Huang EY, Kuo TT, Hoffer BJ, Miller J, Chou YC, Chiang YH. Dopamine release in the nucleus accumbens is altered following traumatic brain injury. Neuroscience. PMID 28196657 DOI: 10.1016/J.Neuroscience.2017.02.001  0.324
2017 Hao F, Yang C, Chen SS, Wang YY, Zhou W, Hao Q, Lu T, Hoffer B, Zhao LR, Duan WM, Xu QY. Long-Term Protective Effects of AAV9-Mesencephalic Astrocyte-Derived Neurotrophic Factor Gene Transfer in Parkinsonian Rats. Experimental Neurology. PMID 28131727 DOI: 10.1016/j.expneurol.2017.01.008  0.4
2016 Filichia E, Hoffer B, Qi X, Luo Y. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Scientific Reports. 6: 32656. PMID 27619562 DOI: 10.1038/Srep32656  0.338
2016 Wang JY, Huang YN, Chiu CC, Tweedie D, Luo W, Pick CG, Chou SY, Luo Y, Hoffer BJ, Greig NH, Wang JY. Erratum to: Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat. Journal of Neuroinflammation. 13: 228. PMID 27616060 DOI: 10.1186/s12974-016-0668-6  0.354
2016 Yang LY, Greig NH, Huang YN, Hsieh TH, Tweedie D, Yu QS, Hoffer BJ, Luo Y, Kao YC, Wang JY. Post-traumatic administration of the p53 inactivator pifithrin-α oxygen analogue reduces hippocampal neuronal loss and improves cognitive deficits after experimental traumatic brain injury. Neurobiology of Disease. PMID 27553877 DOI: 10.1016/j.nbd.2016.08.012  0.307
2016 Sheng Y, Filichia E, Shick E, Preston KL, Phillips KA, Cooperman L, Lin Z, Tesar P, Hoffer B, Luo Y. Using iPSC-derived human DA neurons from opioid-dependent subjects to study dopamine dynamics. Brain and Behavior. 6: e00491. PMID 27547496 DOI: 10.1002/Brb3.491  0.354
2016 Wang JY, Huang YN, Chiu CC, Tweedie D, Luo W, Pick CG, Chou SY, Luo Y, Hoffer BJ, Greig NH, Wang JY. Pomalidomide mitigates neuronal loss, neuroinflammation, and behavioral impairments induced by traumatic brain injury in rat. Journal of Neuroinflammation. 13: 168. PMID 27353053 DOI: 10.1186/s12974-016-0631-6  0.306
2016 Qi X, Davis B, Chiang YH, Filichia E, Barnett A, Greig NH, Hoffer B, Luo Y. Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model. Journal of Neurochemistry. PMID 27317935 DOI: 10.1111/Jnc.13706  0.397
2016 Zhou X, Pace J, Filichia E, Lv T, Davis B, Hoffer B, Selman W, Luo Y. Dopaminergic neurons. Experimental Neurology. PMID 27317298 DOI: 10.1016/j.expneurol.2016.06.013  0.388
2016 Tweedie D, Fukui K, Li Y, Yu QS, Barak S, Tamargo IA, Rubovitch V, Holloway HW, Lehrmann E, Wood WH, Zhang Y, Becker KG, Perez E, Van Praag H, Luo Y, ... Hoffer BJ, et al. Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms. Plos One. 11: e0156493. PMID 27254111 DOI: 10.1371/Journal.Pone.0156493  0.312
2016 Liu HS, Shen H, Luo Y, Hoffer BJ, Wang Y, Yang Y. Post-treatment with cocaine- and amphetamine-regulated transcript enhances infarct resolution, reinnervation, and angiogenesis in stroke rats - an MRI study. Nmr in Biomedicine. 29: 361-70. PMID 26915794 DOI: 10.1002/nbm.3461  0.304
2015 Luo Y, Hoffer A, Hoffer B, Qi X. Mitochondria: A Therapeutic Target for Parkinson's Disease? International Journal of Molecular Sciences. 16: 20704-30. PMID 26340618 DOI: 10.3390/Ijms160920704  0.307
2015 Shan L, Diaz O, Zhang Y, Ladenheim B, Cadet JL, Chiang YH, Olson L, Hoffer BJ, Bäckman CM. l-Dopa induced dyskinesias in Parkinsonian mice: Disease severity or l-Dopa history. Brain Research. PMID 26086365 DOI: 10.1016/j.brainres.2015.06.005  0.743
2015 Baratz R, Tweedie D, Wang JY, Rubovitch V, Luo W, Hoffer BJ, Greig NH, Pick CG. Transiently lowering tumor necrosis factor-α synthesis ameliorates neuronal cell loss and cognitive impairments induced by minimal traumatic brain injury in mice. Journal of Neuroinflammation. 12: 45. PMID 25879458 DOI: 10.1186/s12974-015-0237-4  0.333
2015 Yang LY, Chu YH, Tweedie D, Yu QS, Pick CG, Hoffer BJ, Greig NH, Wang JY. Post-trauma administration of the pifithrin-α oxygen analog improves histological and functional outcomes after experimental traumatic brain injury. Experimental Neurology. 269: 56-66. PMID 25819102 DOI: 10.1016/j.expneurol.2015.03.015  0.303
2015 Filichia E, Shen H, Zhou X, Qi X, Jin K, Greig N, Hoffer B, Luo Y. Forebrain neuronal specific ablation of p53 gene provides protection in a cortical ischemic stroke model. Neuroscience. 295: 1-10. PMID 25779964 DOI: 10.1016/J.Neuroscience.2015.03.018  0.332
2015 Chen YH, Huang EY, Kuo TT, Ma HI, Hoffer BJ, Tsui PF, Tsai JJ, Chou YC, Chiang YH. Dopamine Release Impairment in Striatum After Different Levels of Cerebral Cortical Fluid Percussion Injury. Cell Transplantation. 24: 2113-28. PMID 25198499 DOI: 10.3727/096368914X683584  0.33
2014 Ross JM, Coppotelli G, Hoffer BJ, Olson L. Maternally transmitted mitochondrial DNA mutations can reduce lifespan. Scientific Reports. 4: 6569. PMID 25299268 DOI: 10.1038/Srep06569  0.652
2013 Ross JM, Stewart JB, Hagström E, Brené S, Mourier A, Coppotelli G, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG. Germline mitochondrial DNA mutations aggravate ageing and can impair brain development. Nature. 501: 412-5. PMID 23965628 DOI: 10.1038/Nature12474  0.639
2013 Luo Y, Shen H, Liu HS, Yu SJ, Reiner DJ, Harvey BK, Hoffer BJ, Yang Y, Wang Y. CART peptide induces neuroregeneration in stroke rats. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 300-10. PMID 23211962 DOI: 10.1038/Jcbfm.2012.172  0.561
2013 Eakin K, Hoffer B, Miller J. Substantia nigra vulnerability after a single moderate diffuse brain injury in the rat. Experimental Neurology. 240: 103-7. PMID 23153576 DOI: 10.1016/J.Expneurol.2012.11.005  0.3
2013 Tweedie D, Rachmany L, Rubovitch V, Lehrmann E, Zhang Y, Becker KG, Perez E, Miller J, Hoffer BJ, Greig NH, Pick CG. Exendin-4, a glucagon-like peptide-1 receptor agonist prevents mTBI-induced changes in hippocampus gene expression and memory deficits in mice. Experimental Neurology. 239: 170-82. PMID 23059457 DOI: 10.1016/J.Expneurol.2012.10.001  0.323
2013 Sterky FH, Pernold K, Harvey BK, Lindqvist E, Hoffer BJ, Olson L. Glial cell line-derived neurotrophic factor partially ameliorates motor symptoms without slowing neurodegeneration in mice with respiratory chain-deficient dopamine neurons. Cell Transplantation. 22: 1529-39. PMID 23051605 DOI: 10.3727/096368912X657693  0.73
2013 Rachmany L, Tweedie D, Li Y, Rubovitch V, Holloway HW, Miller J, Hoffer BJ, Greig NH, Pick CG. Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice. Age (Dordrecht, Netherlands). 35: 1621-36. PMID 22892942 DOI: 10.1007/s11357-012-9464-0  0.342
2012 Zhang Y, Granholm AC, Huh K, Shan L, Diaz-Ruiz O, Malik N, Olson L, Hoffer BJ, Lupica CR, Hoffman AF, Bäckman CM. PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice. Brain : a Journal of Neurology. 135: 2736-49. PMID 22961549 DOI: 10.1093/Brain/Aws196  0.812
2012 Zigmond MJ, Cameron JL, Hoffer BJ, Smeyne RJ. Neurorestoration by physical exercise: moving forward. Parkinsonism & Related Disorders. 18: S147-50. PMID 22166417 DOI: 10.1016/S1353-8020(11)70046-3  0.585
2012 Airavaara M, Harvey BK, Voutilainen MH, Shen H, Chou J, Lindholm P, Lindahl M, Tuominen RK, Saarma M, Hoffer B, Wang Y. CDNF protects the nigrostriatal dopamine system and promotes recovery after MPTP treatment in mice. Cell Transplantation. 21: 1213-23. PMID 21943517 DOI: 10.3727/096368911X600948  0.645
2012 Airavaara M, Harvey BK, Voutilainen MH, Shen H, Chou J, Lindholm P, Lindahl M, Tuominen RK, Saarma M, Wang Y, Hoffer B. 3.217 Cdnf Protects The Nigrostriatal Dopamine System And Promotes Recovery After Mptp Treatment In Mice Parkinsonism & Related Disorders. 18. DOI: 10.1016/S1353-8020(11)70890-2  0.601
2011 Rubovitch V, Ten-Bosch M, Zohar O, Harrison CR, Tempel-Brami C, Stein E, Hoffer BJ, Balaban CD, Schreiber S, Chiu WT, Pick CG. A mouse model of blast-induced mild traumatic brain injury. Experimental Neurology. 232: 280-9. PMID 21946269 DOI: 10.1016/J.Expneurol.2011.09.018  0.316
2011 Hoffer BJ, Harvey BK. Is GDNF beneficial in Parkinson disease? Nature Reviews. Neurology. 7: 600-2. PMID 21931353 DOI: 10.1038/Nrneurol.2011.149  0.576
2011 Harvey BK, Airavaara M, Hinzman J, Wires EM, Chiocco MJ, Howard DB, Shen H, Gerhardt G, Hoffer BJ, Wang Y. Targeted over-expression of glutamate transporter 1 (GLT-1) reduces ischemic brain injury in a rat model of stroke. Plos One. 6: e22135. PMID 21853027 DOI: 10.1371/Journal.Pone.0022135  0.784
2011 Chou J, Greig NH, Reiner D, Hoffer BJ, Wang Y. Enhanced survival of dopaminergic neuronal transplants in hemiparkinsonian rats by the p53 inactivator PFT-α. Cell Transplantation. 20: 1351-9. PMID 21294958 DOI: 10.3727/096368910X557173  0.387
2011 Good CH, Hoffman AF, Hoffer BJ, Chefer VI, Shippenberg TS, Bäckman CM, Larsson NG, Olson L, Gellhaar S, Galter D, Lupica CR. Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1333-44. PMID 21233488 DOI: 10.1096/Fj.10-173625  0.804
2011 Airavaara M, Pickens CL, Stern AL, Wihbey KA, Harvey BK, Bossert JM, Liu QR, Hoffer BJ, Shaham Y. Endogenous GDNF in ventral tegmental area and nucleus accumbens does not play a role in the incubation of heroin craving. Addiction Biology. 16: 261-72. PMID 21182575 DOI: 10.1111/J.1369-1600.2010.00281.X  0.591
2011 Harvey BK, Richie CT, Hoffer BJ, Airavaara M. Transgenic animal models of neurodegeneration based on human genetic studies. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 27-45. PMID 20931247 DOI: 10.1007/S00702-010-0476-6  0.571
2010 Airavaara M, Richie C, Castillo PJ, Chiocco MJ, Howard DB, Peranen J, Liu C, Fang S, Wang Y, Hoffer BJ, Harvey BK. Protective Effects of Mesencephalic Astrocyte-Derived Neurotrophic Factor (MANF) Against lschemia and Endoplasmic Reticulum Stress Cell Transplantation. 19: 330-331. PMID 28849959 DOI: 10.3727/096368910X495370  0.566
2010 Luo Y, Wang Y, Kuang SY, Chiang YH, Hoffer B. Decreased level of Nurr1 in heterozygous young adult mice leads to exacerbated acute and long-term toxicity after repeated methamphetamine exposure Plos One. 5. PMID 21151937 DOI: 10.1371/journal.pone.0015193  0.341
2010 Ross JM, Öberg J, Brené S, Coppotelli G, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ, Olson L. High brain lactate is a hallmark of aging and caused by a shift in the lactate dehydrogenase A/B ratio. Proceedings of the National Academy of Sciences of the United States of America. 107: 20087-92. PMID 21041631 DOI: 10.1073/Pnas.1008189107  0.652
2010 Airavaara M, Chiocco MJ, Howard DB, Zuchowski KL, Peränen J, Liu C, Fang S, Hoffer BJ, Wang Y, Harvey BK. Widespread cortical expression of MANF by AAV serotype 7: localization and protection against ischemic brain injury. Experimental Neurology. 225: 104-13. PMID 20685313 DOI: 10.1016/J.Expneurol.2010.05.020  0.621
2010 Galter D, Pernold K, Yoshitake T, Lindqvist E, Hoffer B, Kehr J, Larsson NG, Olson L. MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease. Genes, Brain, and Behavior. 9: 173-81. PMID 20002202 DOI: 10.1111/j.1601-183X.2009.00542.x  0.537
2010 Westerlund M, Hoffer B, Olson L. Parkinson's disease: Exit toxins, enter genetics. Progress in Neurobiology. 90: 146-56. PMID 19925845 DOI: 10.1016/j.pneurobio.2009.11.001  0.537
2009 Luo Y, Kuang SY, Hoffer B. How useful are stem cells in PD therapy? Parkinsonism and Related Disorders. 15: S171-S175. PMID 20082984 DOI: 10.1016/S1353-8020(09)70808-9  0.331
2009 Tsai SY, Hayashi T, Harvey BK, Wang Y, Wu WW, Shen RF, Zhang Y, Becker KG, Hoffer BJ, Su TP. Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 22468-73. PMID 20018732 DOI: 10.1073/Pnas.0909089106  0.563
2009 Karlén A, Karlsson TE, Mattsson A, Lundströmer K, Codeluppi S, Pham TM, Bäckman CM, Ogren SO, Aberg E, Hoffman AF, Sherling MA, Lupica CR, Hoffer BJ, Spenger C, Josephson A, et al. Nogo receptor 1 regulates formation of lasting memories. Proceedings of the National Academy of Sciences of the United States of America. 106: 20476-81. PMID 19915139 DOI: 10.1073/Pnas.0905390106  0.769
2009 Luo Y, Sarabi SA, Backman C, Shan L, Hoffer B, Federoff H. Expression pattern of NuIP gene in adult mouse brain. Brain Research. 1302: 42-53. PMID 19765553 DOI: 10.1016/J.Brainres.2009.09.026  0.745
2009 Luo Y, Kuo CC, Shen H, Chou J, Greig NH, Hoffer BJ, Wang Y. Delayed treatment with a p53 inhibitor enhances recovery in stroke brain. Annals of Neurology. 65: 520-30. PMID 19475672 DOI: 10.1002/ana.21592  0.305
2009 Harvey BK, Chou J, Shen H, Hoffer BJ, Wang Y. Diadenosine tetraphosphate reduces toxicity caused by high-dose methamphetamine administration. Neurotoxicology. 30: 436-44. PMID 19442829 DOI: 10.1016/J.Neuro.2009.02.003  0.623
2009 Airavaara M, Shen H, Kuo CC, Peränen J, Saarma M, Hoffer B, Wang Y. Mesencephalic astrocyte-derived neurotrophic factor reduces ischemic brain injury and promotes behavioral recovery in rats Journal of Comparative Neurology. 515: 116-124. PMID 19399876 DOI: 10.1002/cne.22039  0.335
2009 Lu L, Wang X, Wu P, Xu C, Zhao M, Morales M, Harvey BK, Hoffer BJ, Shaham Y. Role of ventral tegmental area glial cell line-derived neurotrophic factor in incubation of cocaine craving. Biological Psychiatry. 66: 137-45. PMID 19345340 DOI: 10.1016/J.Biopsych.2009.02.009  0.666
2009 Shen H, Kuo CC, Chou J, Delvolve A, Jackson SN, Post J, Woods AS, Hoffer BJ, Wang Y, Harvey BK. Astaxanthin reduces ischemic brain injury in adult rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 1958-68. PMID 19218497 DOI: 10.1096/Fj.08-123281  0.556
2009 Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 106: 1285-90. PMID 19164583 DOI: 10.1073/Pnas.0806720106  0.632
2009 Shen H, Luo Y, Kuo CC, Deng X, Chang CF, Harvey BK, Hoffer BJ, Wang Y. 9-Cis-retinoic acid reduces ischemic brain injury in rodents via bone morphogenetic protein. Journal of Neuroscience Research. 87: 545-55. PMID 18803283 DOI: 10.1002/Jnr.21865  0.6
2009 Bäckman CM, Zhang Y, Malik N, Shan L, Hoffer BJ, Westphal H, Tomac AC. Generalized tetracycline induced Cre recombinase expression through the ROSA26 locus of recombinant mice. Journal of Neuroscience Methods. 176: 16-23. PMID 18801387 DOI: 10.1016/j.jneumeth.2008.08.024  0.645
2008 Zaman V, Boger HA, Granholm AC, Rohrer B, Moore A, Buhusi M, Gerhardt GA, Hoffer BJ, Middaugh LD. The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior. The European Journal of Neuroscience. 28: 1557-68. PMID 18973577 DOI: 10.1111/J.1460-9568.2008.06456.X  0.801
2008 Boger HA, Middaugh LD, Zaman V, Hoffer B, Granholm AC. Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene. Brain Research. 1241: 18-28. PMID 18822276 DOI: 10.1016/J.Brainres.2008.09.011  0.797
2008 Chou J, Harvey BK, Ebendal T, Hoffer B, Wang Y. Nigrostriatal alterations in bone morphogenetic protein receptor II dominant negative mice. Acta Neurochirurgica. Supplement. 101: 93-8. PMID 18642641 DOI: 10.1007/978-3-211-78205-7_16  0.637
2008 Harvey BK, Wang Y, Hoffer BJ. Transgenic rodent models of Parkinson's disease. Acta Neurochirurgica. Supplement. 101: 89-92. PMID 18642640 DOI: 10.1007/978-3-211-78205-7_15  0.608
2008 Sarabi AS, Shen H, Wang Y, Hoffer BJ, Bäckman CM. Gene expression patterns in mouse cortical penumbra after focal ischemic brain injury and reperfusion. Journal of Neuroscience Research. 86: 2912-24. PMID 18506852 DOI: 10.1002/jnr.21734  0.653
2008 Chou J, Luo Y, Kuo CC, Powers K, Shen H, Harvey BK, Hoffer BJ, Wang Y. Bone morphogenetic protein-7 reduces toxicity induced by high doses of methamphetamine in rodents. Neuroscience. 151: 92-103. PMID 18082966 DOI: 10.1016/J.Neuroscience.2007.10.044  0.627
2008 Olson L, Björklund H, Ebendal T, Hedlund KO, Hoffer B. Factors Regulating Growth of Catecholamine-Containing Nerves, as Revealed by Transplantation and Explantation Studies Development of the Autonomic Nervous System. 213-231. DOI: 10.1002/9780470720653.ch11  0.483
2007 Chiocco MJ, Harvey BK, Wang Y, Hoffer BJ. Neurotrophic factors for the treatment of Parkinson's disease. Parkinsonism & Related Disorders. 13: S321-8. PMID 18267258 DOI: 10.1016/S1353-8020(08)70024-5  0.608
2007 Harvey BK, Chen GJ, Schoen CJ, Lee CT, Howard DB, Dillon-Carter O, Coggiano M, Freed WJ, Wang Y, Hoffer BJ, Sanchez JF. An immortalized rat ventral mesencephalic cell line, RTC4, is protective in a rodent model of stroke. Cell Transplantation. 16: 483-91. PMID 17708338 DOI: 10.3727/000000007783464984  0.611
2007 Tsai MJ, Weng CF, Shyue SK, Liou DY, Chen CH, Chiu CW, Yang TH, Pan HA, Liao RI, Kuo HS, Huang MC, Huang WC, Hoffer BJ, Cheng H. Dual effect of adenovirus-mediated transfer of BMP7 in mixed neuron-glial cultures: neuroprotection and cellular differentiation. Journal of Neuroscience Research. 85: 2950-9. PMID 17628501 DOI: 10.1002/jnr.21395  0.341
2007 Tweedie D, Milman A, Holloway HW, Li Y, Harvey BK, Shen H, Pistell PJ, Lahiri DK, Hoffer BJ, Wang Y, Pick CG, Greig NH. Apoptotic and behavioral sequelae of mild brain trauma in mice. Journal of Neuroscience Research. 85: 805-15. PMID 17243171 DOI: 10.1002/Jnr.21160  0.587
2007 Ekstrand MI, Terzioglu M, Galter D, Zhu S, Hofstetter C, Lindqvist E, Thams S, Bergstrand A, Hansson FS, Trifunovic A, Hoffer B, Cullheim S, Mohammed AH, Olson L, Larsson NG. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proceedings of the National Academy of Sciences of the United States of America. 104: 1325-30. PMID 17227870 DOI: 10.1073/pnas.0605208103  0.537
2007 Bäckman CM, Shan L, Zhang Y, Hoffer BJ, Tomac AC. Alterations in prodynorphin, proenkephalin, and GAD67 mRNA levels in the aged human putamen: correlation with Parkinson's disease. Journal of Neuroscience Research. 85: 798-804. PMID 17203488 DOI: 10.1002/jnr.21164  0.645
2007 af Bjerkén S, Boger HA, Nelson M, Hoffer BJ, Granholm AC, Strömberg I. Effects of glial cell line-derived neurotrophic factor deletion on ventral mesencephalic organotypic tissue cultures. Brain Research. 1133: 10-9. PMID 17184739 DOI: 10.1016/j.brainres.2006.11.052  0.801
2006 Boger HA, Middaugh LD, Huang P, Zaman V, Smith AC, Hoffer BJ, Tomac AC, Granholm AC. A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra. Experimental Neurology. 202: 336-47. PMID 16889771 DOI: 10.1016/J.Expneurol.2006.06.006  0.796
2006 Bäckman CM, Malik N, Zhang Y, Shan L, Grinberg A, Hoffer BJ, Westphal H, Tomac AC. Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis (New York, N.Y. : 2000). 44: 383-90. PMID 16865686 DOI: 10.1002/dvg.20228  0.645
2006 Bäckman CM, Shan L, Zhang YJ, Hoffer BJ, Leonard S, Troncoso JC, Vonsatel P, Tomac AC. Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study. Molecular and Cellular Endocrinology. 252: 160-6. PMID 16644101 DOI: 10.1016/J.Mce.2006.03.013  0.695
2006 Howard DB, Powers K, Hoffer BJ, Wang Y, Harvey BK. 120. Tropism and Toxicity of Adeno-Associated Viral Vector Serotypes on Neurons and Glia In Vitro Molecular Therapy. 13: S49. DOI: 10.1016/J.Ymthe.2006.08.140  0.6
2006 Schoen C, Sanchez J, Harvey B, Dillon-Carter O, Chen G, Wang Y, Freed W, Hoffer B. Transplantation of a ventral mesencephalon-derived cell line, RTC4, reduces ischemic brain damage in rats Experimental Neurology. 198: 587-588. DOI: 10.1016/J.Expneurol.2006.02.089  0.573
2005 Chiang YH, Borlongan CV, Zhou FC, Hoffer BJ, Wang Y. Transplantation of fetal kidney cells: neuroprotection and neuroregeneration. Cell Transplantation. 14: 1-9. PMID 15789657 DOI: 10.3727/000000005783983304  0.344
2005 Harvey BK, Hoffer BJ, Wang Y. Stroke and TGF-beta proteins: glial cell line-derived neurotrophic factor and bone morphogenetic protein. Pharmacology & Therapeutics. 105: 113-25. PMID 15670622 DOI: 10.1016/J.Pharmthera.2004.09.003  0.596
2004 Bäckman CM, Zhang Y, Hoffer BJ, Tomac AC. Tetracycline-inducible expression systems for the generation of transgenic animals: a comparison of various inducible systems carried in a single vector. Journal of Neuroscience Methods. 139: 257-62. PMID 15488239 DOI: 10.1016/j.jneumeth.2004.05.012  0.645
2004 Harvey BK, Mark A, Chou J, Chen GJ, Hoffer BJ, Wang Y. Neurotrophic effects of bone morphogenetic protein-7 in a rat model of Parkinson's disease. Brain Research. 1022: 88-95. PMID 15353217 DOI: 10.1016/J.Brainres.2004.06.072  0.648
2004 Quintero EM, Willis LM, Zaman V, Lee J, Boger HA, Tomac A, Hoffer BJ, Strömberg I, Granholm AC. Glial cell line-derived neurotrophic factor is essential for neuronal survival in the locus coeruleus-hippocampal noradrenergic pathway. Neuroscience. 124: 137-46. PMID 14960346 DOI: 10.1016/j.neuroscience.2003.11.001  0.812
2003 Zaman V, Li Z, Middaugh L, Ramamoorthy S, Rohrer B, Nelson ME, Tomac AC, Hoffer BJ, Gerhardt GA, Granholm AC. The Noradrenergic System of Aged GDNF Heterozygous Mice. Cell Transplantation. 12: 291-303. PMID 28853928 DOI: 10.3727/000000003108746740  0.402
2003 Bäckman C, Zhang Y, Hoffer BJ, Tomac AC. Short interfering RNAs (siRNAs) for reducing dopaminergic phenotypic markers. Journal of Neuroscience Methods. 131: 51-6. PMID 14659823 DOI: 10.1016/S0165-0270(03)00236-X  0.645
2003 Harvey BK, Chang CF, Chiang YH, Bowers WJ, Morales M, Hoffer BJ, Wang Y, Federoff HJ. HSV amplicon delivery of glial cell line-derived neurotrophic factor is neuroprotective against ischemic injury. Experimental Neurology. 183: 47-55. PMID 12957487 DOI: 10.1016/S0014-4886(03)00080-3  0.743
2003 Bäckman C, You ZB, Perlmann T, Hoffer BJ. Elevated locomotor activity without altered striatal dopamine contents in Nurr1 heterozygous mice after acute exposure to methamphetamine. Behavioural Brain Research. 143: 95-100. PMID 12842300 DOI: 10.1016/S0166-4328(03)00029-9  0.645
2003 Zaman V, Li Z, Middaugh L, Ramamoorthy S, Rohrer B, Nelson ME, Tomac AC, Hoffer BJ, Gerhardt GA, Granholm ACh. The noradrenergic system of aged GDNF heterozygous mice. Cell Transplantation. 12: 291-303. PMID 12797383  0.744
2003 Sarabi A, Chang CF, Wang Y, Tomac AC, Hoffer BJ, Morales M. Differential expression of the cell line-derived neurotrophic factor (GDNF) receptor GFRalpha1 in heterozygous Gfralpha1 null-mutant mice after stroke. Neuroscience Letters. 341: 241-5. PMID 12697293 DOI: 10.1016/S0304-3940(03)00195-2  0.532
2003 Chang CF, Lin SZ, Chiang YH, Morales M, Chou J, Lein P, Chen HL, Hoffer BJ, Wang Y. Intravenous administration of bone morphogenetic protein-7 after ischemia improves motor function in stroke rats. Stroke; a Journal of Cerebral Circulation. 34: 558-64. PMID 12574575 DOI: 10.1161/01.Str.0000051507.64423.00  0.468
2003 Sarabi A, Hoffer BJ, Olson L, Morales M. Glial cell line neurotrophic factor-family receptor alpha-1 is present in central neurons with distinct phenotypes. Neuroscience. 116: 261-73. PMID 12535958 DOI: 10.1016/S0306-4522(02)00559-6  0.698
2002 Borlongan CV, Emerich DF, Hoffer BJ, Bartus RT. Bradykinin receptor agonist facilitates low-dose cyclosporine-A protection against 6-hydroxydopamine neurotoxicity. Brain Research. 956: 211-20. PMID 12445688 DOI: 10.1016/S0006-8993(02)03474-1  0.332
2002 Chang CF, Morales M, Chou J, Chen HL, Hoffer B, Wang Y. Bone morphogenetic proteins are involved in fetal kidney tissue transplantation-induced neuroprotection in stroke rats Neuropharmacology. 43: 418-426. PMID 12243771 DOI: 10.1016/S0028-3908(02)00092-8  0.555
2002 Tomac AC, Agulnick AD, Haughey N, Chang CF, Zhang Y, Bäckman C, Morales M, Mattson MP, Wang Y, Westphal H, Hoffer BJ. Effects of cerebral ischemia in mice deficient in Persephin. Proceedings of the National Academy of Sciences of the United States of America. 99: 9521-6. PMID 12093930 DOI: 10.1073/Pnas.152535899  0.734
2002 McGrath J, Lintz E, Hoffer BJ, Gerhardt GA, Quintero EM, Granholm AC. Adeno-associated viral delivery of GDNF promotes recovery of dopaminergic phenotype following a unilateral 6-hydroxydopamine lesion. Cell Transplantation. 11: 215-27. PMID 12075987 DOI: 10.3727/096020198389988  0.75
2001 Sarabi A, Hoffer BJ, Olson L, Morales M. GFRalpha-1 mRNA in dopaminergic and nondopaminergic neurons in the substantia nigra and ventral tegmental area. The Journal of Comparative Neurology. 441: 106-17. PMID 11745638 DOI: 10.1002/Cne.1400  0.698
2001 Wang Y, Chang CF, Morales M, Chou J, Chen HL, Chiang YH, Lin SZ, Cadet JL, Deng X, Wang JY, Chen SY, Kaplan PL, Hoffer BJ. Bone morphogenetic protein-6 reduces ischemia-induced brain damage in rats. Stroke; a Journal of Cerebral Circulation. 32: 2170-8. PMID 11546913  0.497
2001 Chen MT, Morales M, Woodward DJ, Hoffer BJ, Janak PH. In vivo extracellular recording of striatal neurons in the awake rat following unilateral 6-hydroxydopamine lesions. Experimental Neurology. 171: 72-83. PMID 11520122 DOI: 10.1006/Exnr.2001.7730  0.581
2001 Wang JY, Wu JN, Cherng TL, Hoffer BJ, Chen HH, Borlongan CV, Wang Y. Vitamin D(3) attenuates 6-hydroxydopamine-induced neurotoxicity in rats. Brain Research. 904: 67-75. PMID 11516412 DOI: 10.1016/S0006-8993(01)02450-7  0.38
2001 Borlongan CV, Zhou FC, Hayashi T, Su TP, Hoffer BJ, Wang Y. Involvement of GDNF in neuronal protection against 6-OHDA-induced parkinsonism following intracerebral transplantation of fetal kidney tissues in adult rats. Neurobiology of Disease. 8: 636-46. PMID 11493028 DOI: 10.1006/nbdi.2001.0410  0.397
2001 Sarabi A, Chang CF, Wang Y, Hoffer BJ, Morales M. Time course study of GFRalpha-1 expression in an animal model of stroke. Experimental Neurology. 170: 283-9. PMID 11476594 DOI: 10.1006/Exnr.2001.7714  0.526
2001 Bäckman C, Hoffer BJ, Misawa H, Morales M. Cellular mRNA expression of the transcription factor NGFI-B suggests a gene regulatory role in striatal opiate-peptide neurons. Brain Research. 903: 26-32. PMID 11382384 DOI: 10.1016/S0006-8993(01)02332-0  0.726
2001 Chiang Y, Morales M, Zhou FC, Borlongan C, Hoffer BJ, Wang Y. Fetal intra-nigral ventral mesencephalon and kidney tissue bridge transplantation restores the nigrostriatal dopamine pathway in hemi-parkinsonian rats. Brain Research. 889: 200-7. PMID 11166704 DOI: 10.1016/S0006-8993(00)03133-4  0.522
2000 Sarabi A, Hoffer BJ, Olson L, Morales M. GFR alpha-1 is expressed in parvalbumin GABAergic neurons in the hippocampus. Brain Research. 877: 262-70. PMID 10986340 DOI: 10.1016/S0006-8993(00)02682-2  0.666
2000 Granholm AC, Reyland M, Albeck D, Sanders L, Gerhardt G, Hoernig G, Shen L, Westphal H, Hoffer B. Glial cell line-derived neurotrophic factor is essential for postnatal survival of midbrain dopamine neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3182-90. PMID 10777782 DOI: 10.1523/Jneurosci.20-09-03182.2000  0.774
2000 Wang Y, Chiang YH, Su TP, Hayashi T, Morales M, Hoffer BJ, Lin SZ. Vitamin D(3) attenuates cortical infarction induced by middle cerebral arterial ligation in rats. Neuropharmacology. 39: 873-80. PMID 10699453 DOI: 10.1016/S0028-3908(99)00255-5  0.461
2000 Tomac AC, Grinberg A, Huang SP, Nosrat C, Wang Y, Borlongan C, Lin SZ, Chiang YH, Olson L, Westphal H, Hoffer BJ. Glial cell line-derived neurotrophic factor receptor alpha1 availability regulates glial cell line-derived neurotrophic factor signaling: evidence from mice carrying one or two mutated alleles. Neuroscience. 95: 1011-23. PMID 10682708 DOI: 10.1016/S0306-4522(99)00503-5  0.54
1999 Bäckman C, Perlmann T, Wallén A, Hoffer BJ, Morales M. A selective group of dopaminergic neurons express Nurr1 in the adult mouse brain. Brain Research. 851: 125-32. PMID 10642835 DOI: 10.1016/S0006-8993(99)02149-6  0.76
1999 Chiang YH, Lin SZ, Borlongan CV, Hoffer BJ, Morales M, Wang Y. Transplantation of fetal kidney tissue reduces cerebral infarction induced by middle cerebral artery ligation. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 1329-35. PMID 10598937 DOI: 10.1097/00004647-199912000-00006  0.49
1999 Granholm AC, Sanders LA, Ickes B, Albeck D, Hoffer BJ, Young DA, Kaplan PL. Effects of osteogenic protein-1 (OP-1) treatment on fetal spinal cord transplants to the anterior chamber of the eye. Cell Transplantation. 8: 75-85. PMID 10338277  0.797
1998 Kobayashi S, Ogren SO, Hoffer BJ, Olson L. Dopamine D1 and D2 receptor-mediated acute and long-lasting behavioral effects of glial cell line-derived neurotrophic factor administered into the striatum. Experimental Neurology. 154: 302-14. PMID 9878169 DOI: 10.1006/exnr.1998.6952  0.483
1998 David DJ, Zahniser NR, Hoffer BJ, Gerhardt GA. In vivo electrochemical studies of dopamine clearance in subregions of rat nucleus accumbens: differential properties of the core and shell. Experimental Neurology. 153: 277-86. PMID 9784287 DOI: 10.1006/exnr.1998.6898  0.445
1998 Widenfalk J, Tomac A, Lindqvist E, Hoffer B, Olson L. GFRalpha-3, a protein related to GFRalpha-1, is expressed in developing peripheral neurons and ensheathing cells. The European Journal of Neuroscience. 10: 1508-17. PMID 9749804 DOI: 10.1046/j.1460-9568.1998.00192.x  0.483
1998 Granholm AC, Albeck D, Bäckman C, Curtis M, Ebendal T, Friden P, Henry M, Hoffer B, Kordower J, Rose GM, Söderström S, Bartus RT. A non-invasive system for delivering neural growth factors across the blood-brain barrier: a review. Reviews in the Neurosciences. 9: 31-55. PMID 9683326 DOI: 10.1515/Revneuro.1998.9.1.31  0.805
1998 Olson L, Cheng H, Zetterström RH, Solomin L, Jansson L, Giménez-Llort L, Hoffer BJ, Perlmann T. On CNS repair and protection strategies: novel approaches with implications for spinal cord injury and Parkinson's disease. Brain Research. Brain Research Reviews. 26: 302-5. PMID 9651546 DOI: 10.1016/S0165-0173(97)00051-9  0.579
1998 Cheng H, Fraidakis M, Blombäck B, Lapchak P, Hoffer B, Olson L. Characterization of a fibrin glue-GDNF slow-release preparation. Cell Transplantation. 7: 53-61. PMID 9489763 DOI: 10.1016/S0963-6897(97)00122-X  0.537
1998 Gash DM, Gerhardt GA, Hoffer BJ. Effects of glial cell line-derived neurotrophic factor on the nigrostriatal dopamine system in rodents and nonhuman primates. Advances in Pharmacology (San Diego, Calif.). 42: 911-5. PMID 9328046 DOI: 10.1016/S1054-3589(08)60895-9  0.46
1998 Cheng H, Fraidakis M, Blombäck B, Lapchak P, Hoffer B, Olson L. Characterization of a Fibrin Glue-Gdnf Slow-Release Preparation Cell Transplantation. 7: 53-61. DOI: 10.1177/096368979800700108  0.483
1997 Cheng H, Almström S, Giménez-Llort L, Chang R, Ögren SO, Hoffer B, Olson L. Gait Analysis of Adult Paraplegic Rats after Spinal Cord Repair Experimental Neurology. 148: 544-557. PMID 9417831 DOI: 10.1006/Exnr.1997.6708  0.537
1997 Bäckman C, Rose GM, Bartus RT, Hoffer BJ, Mufson EJ, Granholm AC. Carrier mediated delivery of NGF: alterations in basal forebrain neurons in aged rats revealed using antibodies against low and high affinity NGF receptors. The Journal of Comparative Neurology. 387: 1-11. PMID 9331167 DOI: 10.1002/(Sici)1096-9861(19971013)387:1<1::Aid-Cne1>3.0.Co;2-5  0.783
1997 Shinoda M, Hoffer BJ, Olson L. Minor immunoreactivity in GDNF-, BDNF-, or NT-3-treated substantia nigra allografts. Journal of Neural Transplantation & Plasticity. 6: 83-96. PMID 9306240 DOI: 10.1155/NP.1997.83  0.483
1997 Granholm AC, Mott JL, Bowenkamp K, Eken S, Henry S, Hoffer BJ, Lapchak PA, Palmer MR, van Horne C, Gerhardt GA. Glial cell line-derived neurotrophic factor improves survival of ventral mesencephalic grafts to the 6-hydroxydopamine lesioned striatum. Experimental Brain Research. 116: 29-38. PMID 9305812 DOI: 10.1007/Pl00005741  0.762
1997 Luthman J, Friedemann MN, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements of serotonin clearance in rat striatum: effects of neonatal 6-hydroxydopamine-induced serotonin hyperinnervation and serotonin uptake inhibitors. Journal of Neural Transmission (Vienna, Austria : 1996). 104: 379-97. PMID 9295172 DOI: 10.1007/BF01277658  0.405
1997 Hoffman AF, van Horne CG, Eken S, Hoffer BJ, Gerhardt GA. In vivo microdialysis studies on somatodendritic dopamine release in the rat substantia nigra: effects of unilateral 6-OHDA lesions and GDNF. Experimental Neurology. 147: 130-41. PMID 9294410 DOI: 10.1006/Exnr.1997.6571  0.69
1997 Nosrat CA, Tomac A, Hoffer BJ, Olson L. Cellular and developmental patterns of expression of Ret and glial cell line-derived neurotrophic factor receptor alpha mRNAs. Experimental Brain Research. 115: 410-22. PMID 9262196 DOI: 10.1007/PL00005711  0.537
1997 Albeck DS, Hoffer BJ, Quissell D, Sanders LA, Zerbe G, Granholm AC. A non-invasive transport system for GDNF across the blood-brain barrier. Neuroreport. 8: 2293-8. PMID 9243628 DOI: 10.1097/00001756-199707070-00039  0.79
1997 Bowenkamp KE, Lapchak PA, Hoffer BJ, Miller PJ, Bickford PC. Intracerebroventricular glial cell line-derived neurotrophic factor improves motor function and supports nigrostriatal dopamine neurons in bilaterally 6-hydroxydopamine lesioned rats. Experimental Neurology. 145: 104-17. PMID 9184114 DOI: 10.1006/exnr.1997.6436  0.481
1997 Zetterström RH, Solomin L, Jansson L, Hoffer BJ, Olson L, Perlmann T. Dopamine neuron agenesis in Nurr1-deficient mice. Science (New York, N.Y.). 276: 248-50. PMID 9092472 DOI: 10.1126/science.276.5310.248  0.483
1997 Granholm AC, Srivastava N, Mott JL, Henry S, Henry M, Westphal H, Pichel JG, Shen L, Hoffer BJ. Morphological alterations in the peripheral and central nervous systems of mice lacking glial cell line-derived neurotrophic factor (GDNF): immunohistochemical studies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1168-78. PMID 8994069  0.693
1997 Widenfalk J, Nosrat C, Tomac A, Westphal H, Hoffer B, Olson L. Neurturin and Glial Cell Line-Derived Neurotrophic Factor Receptor-β (GDNFR-β), Novel Proteins Related to GDNF and GDNFR-α with Specific Cellular Patterns of Expression Suggesting Roles in the Developing and Adult Nervous System and in Peripheral Organs The Journal of Neuroscience. 17: 8506-8519. DOI: 10.1523/JNEUROSCI.17-21-08506.1997  0.537
1996 Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. GDNF is required for kidney development and enteric innervation. Cold Spring Harbor Symposia On Quantitative Biology. 61: 445-57. PMID 9246473  0.619
1996 Hebert MA, Van Horne CG, Hoffer BJ, Gerhardt GA. Functional effects of GDNF in normal rat striatum: presynaptic studies using in vivo electrochemistry and microdialysis. The Journal of Pharmacology and Experimental Therapeutics. 279: 1181-90. PMID 8968339  0.521
1996 Lorentzon M, Hoffer B, Ebendal T, Olson L, Tomac A. Habrec1, a novel serine/threonine kinase TGF-beta type I-like receptor, has a specific cellular expression suggesting function in the developing organism and adult brain. Experimental Neurology. 142: 351-60. PMID 8934566 DOI: 10.1006/exnr.1996.0204  0.483
1996 Bowenkamp KE, David D, Lapchak PL, Henry MA, Granholm AC, Hoffer BJ, Mahalik TJ. 6-hydroxydopamine induces the loss of the dopaminergic phenotype in substantia nigra neurons of the rat. A possible mechanism for restoration of the nigrostriatal circuit mediated by glial cell line-derived neurotrophic factor. Experimental Brain Research. 111: 1-7. PMID 8891630 DOI: 10.1007/BF00229549  0.71
1996 Nosrat CA, Tomac A, Lindqvist E, Lindskog S, Humpel C, Strömberg I, Ebendal T, Hoffer BJ, Olson L. Cellular expression of GDNF mRNA suggests multiple functions inside and outside the nervous system. Cell and Tissue Research. 286: 191-207. PMID 8854888 DOI: 10.1007/s004410050688  0.483
1996 Trok K, Hoffer B, Olson L. Glial cell line-derived neurotrophic factor enhances survival and growth of prenatal and postnatal spinal cord transplants. Neuroscience. 71: 231-41. PMID 8834405 DOI: 10.1016/0306-4522(95)00412-2  0.483
1996 Bowenkamp KE, Lapchak PA, Hoffer BJ, Bickford PC. Glial cell line-derived neurotrophic factor reverses motor impairment in 16-17 month old rats. Neuroscience Letters. 211: 81-4. PMID 8830849 DOI: 10.1016/0304-3940(96)12729-4  0.481
1996 Shinoda M, Hoffer BJ, Olson L. Interactions of neurotrophic factors GDNF and NT-3, but not BDNF, with the immune system following fetal spinal cord transplantation. Brain Research. 722: 153-67. PMID 8813361 DOI: 10.1016/0006-8993(96)00208-9  0.483
1996 Price ML, Hoffer BJ, Granholm AC. Effects of GDNF on fetal septal forebrain transplants in oculo. Experimental Neurology. 141: 181-9. PMID 8812151 DOI: 10.1006/exnr.1996.0152  0.7
1996 Shinoda M, Hudson JL, Strömberg I, Hoffer BJ, Moorhead JW, Olson L. Microglial cell responses to fetal ventral mesencephalic tissue grafting and to active and adoptive immunizations. Experimental Neurology. 141: 173-80. PMID 8812150 DOI: 10.1006/exnr.1996.0151  0.483
1996 Bäckman C, Rose GM, Hoffer BJ, Henry MA, Bartus RT, Friden P, Granholm AC. Systemic administration of a nerve growth factor conjugate reverses age-related cognitive dysfunction and prevents cholinergic neuron atrophy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5437-42. PMID 8757256 DOI: 10.1523/Jneurosci.16-17-05437.1996  0.781
1996 Pichel JG, Shen L, Sheng HZ, Granholm AC, Drago J, Grinberg A, Lee EJ, Huang SP, Saarma M, Hoffer BJ, Sariola H, Westphal H. Defects in enteric innervation and kidney development in mice lacking GDNF. Nature. 382: 73-6. PMID 8657307 DOI: 10.1038/382073a0  0.687
1996 Gash DM, Zhang Z, Ovadia A, Cass WA, Yi A, Simmerman L, Russell D, Martin D, Lapchak PA, Collins F, Hoffer BJ, Gerhardt GA. Functional recovery in parkinsonian monkeys treated with GDNF. Nature. 380: 252-5. PMID 8637574 DOI: 10.1038/380252A0  0.717
1996 Gerhardt GA, Cass WA, Hudson J, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. In vivo electrochemical studies of dopamine overflow and clearance in the striatum of normal and MPTP-treated rhesus monkeys. Journal of Neurochemistry. 66: 579-88. PMID 8592127 DOI: 10.1046/J.1471-4159.1996.66020579.X  0.69
1995 Gash DM, Zhang Z, Cass WA, Ovadia A, Simmerman L, Martin D, Russell D, Collins F, Hoffer BJ, Gerhardt GA. Morphological and functional effects of intranigrally administered GDNF in normal rhesus monkeys. The Journal of Comparative Neurology. 363: 345-58. PMID 8847404 DOI: 10.1002/Cne.903630302  0.715
1995 Gerhardt GA, Cass WA, Henson M, Zhang Z, Ovadia A, Hoffer BJ, Gash DM. Age-related changes in potassium-evoked overflow of dopamine in the striatum of the rhesus monkey. Neurobiology of Aging. 16: 939-46. PMID 8622785 DOI: 10.1016/0197-4580(95)02013-6  0.67
1995 Tomac A, Lindqvist E, Lin LF, Ogren SO, Young D, Hoffer BJ, Olson L. Protection and repair of the nigrostriatal dopaminergic system by GDNF in vivo. Nature. 373: 335-9. PMID 7830766 DOI: 10.1038/373335a0  0.483
1995 Ebendal T, Tomac A, Hoffer BJ, Olson L. Glial cell line-derived neurotrophic factor stimulates fiber formation and survival in cultured neurons from peripheral autonomic ganglia. Journal of Neuroscience Research. 40: 276-84. PMID 7745621 DOI: 10.1002/jnr.490400217  0.483
1995 Giacobini MM, Zetterström RH, Young D, Hoffer B, Sara V, Olson L. IGF-1 influences olfactory bulb maturation. Evidence from anti-IGF-1 antibody treatment of developing grafts in oculo. Brain Research. Developmental Brain Research. 84: 67-76. PMID 7720219 DOI: 10.1016/0165-3806(94)00154-R  0.483
1995 Tomac A, Widenfalk J, Lin LF, Kohno T, Ebendal T, Hoffer BJ, Olson L. Retrograde axonal transport of glial cell line-derived neurotrophic factor in the adult nigrostriatal system suggests a trophic role in the adult. Proceedings of the National Academy of Sciences of the United States of America. 92: 8274-8. PMID 7667281 DOI: 10.1073/pnas.92.18.8274  0.483
1995 Shinoda M, Hudson JL, Strömberg I, Hoffer BJ, Moorhead JW, Olson L. Allogeneic grafts of fetal dopamine neurons: immunological reactions following active and adoptive immunizations. Brain Research. 680: 180-95. PMID 7663976 DOI: 10.1016/0006-8993(95)00260-W  0.483
1995 Bowenkamp KE, Hoffman AF, Gerhardt GA, Henry MA, Biddle PT, Hoffer BJ, Granholm AC. Glial cell line-derived neurotrophic factor supports survival of injured midbrain dopaminergic neurons. The Journal of Comparative Neurology. 355: 479-89. PMID 7636027 DOI: 10.1002/Cne.903550402  0.814
1994 Hudson JL, Hoffman A, Strömberg I, Hoffer BJ, Moorhead JW. Allogeneic grafts of fetal dopamine neurons: behavioral indices of immunological interactions. Neuroscience Letters. 171: 32-6. PMID 8084493 DOI: 10.1016/0304-3940(94)90597-5  0.626
1994 Humpel C, Hoffer B, Strömberg I, Bektesh S, Collins F, Olson L. Neurons of the hippocampal formation express glial cell line-derived neurotrophic factor messenger RNA in response to kainate-induced excitation. Neuroscience. 59: 791-5. PMID 8058121 DOI: 10.1016/0306-4522(94)90284-4  0.53
1994 Hudson JL, Bickford P, Johansson M, Hoffer BJ, Strömberg I. Target and neurotransmitter specificity of fetal central nervous system transplants: importance for functional reinnervation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 283-90. PMID 7904305 DOI: 10.1523/Jneurosci.14-01-00283.1994  0.481
1994 Hoffer BJ, Hoffman A, Bowenkamp K, Huettl P, Hudson J, Martin D, Lin LF, Gerhardt GA. Glial cell line-derived neurotrophic factor reverses toxin-induced injury to midbrain dopaminergic neurons in vivo. Neuroscience Letters. 182: 107-11. PMID 7891873 DOI: 10.1016/0304-3940(94)90218-6  0.706
1994 Adams CE, Hoffman AF, Hudson JL, Hoffer BJ, Boyson SJ. Chronic treatment with levodopa and/or selegiline does not affect behavioral recovery induced by fetal ventral mesencephalic grafts in unilaterally 6-hydroxydopamine-lesioned rats. Experimental Neurology. 130: 261-8. PMID 7867755 DOI: 10.1006/Exnr.1994.1204  0.608
1994 Freedman R, Strömberg I, Nordström AL, Seiger A, Olson L, Bygdeman M, Wiesel FA, Granholm AC, Hoffer BJ. Neuronal development in embryonic brain tissue derived from schizophrenic women and grafted to animal hosts. Schizophrenia Research. 13: 259-70. PMID 7841140 DOI: 10.1016/0920-9964(94)90051-5  0.734
1993 Luthman J, Friedemann MN, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements of exogenous dopamine clearance in normal and neonatal 6-hydroxydopamine-treated rat striatum. Experimental Neurology. 122: 273-82. PMID 8405264 DOI: 10.1006/exnr.1993.1127  0.479
1993 Hudson JL, van Horne CG, Strömberg I, Brock S, Clayton J, Masserano J, Hoffer BJ, Gerhardt GA. Correlation of apomorphine- and amphetamine-induced turning with nigrostriatal dopamine content in unilateral 6-hydroxydopamine lesioned rats. Brain Research. 626: 167-74. PMID 8281427 DOI: 10.1016/0006-8993(93)90576-9  0.471
1993 Luthman J, Friedemann M, Bickford P, Olson L, Hoffer BJ, Gerhardt GA. In vivo electrochemical measurements and electrophysiological studies of rat striatum following neonatal 6-hydroxydopamine treatment. Neuroscience. 52: 677-87. PMID 7680793 DOI: 10.1016/0306-4522(93)90416-D  0.739
1992 van Horne C, Hoffer BJ, Strömberg I, Gerhardt GA. Clearance and diffusion of locally applied dopamine in normal and 6-hydroxydopamine-lesioned rat striatum. The Journal of Pharmacology and Experimental Therapeutics. 263: 1285-92. PMID 1469634 DOI: 10.1016/B978-0-08-042276-3.50038-0  0.465
1992 Freedman R, Strömberg I, Seiger A, Olson L, Nordström AL, Wiesel FA, Bygdeman M, Wetmore C, Palmer MR, Hoffer BJ. Initial studies of embryonic transplants of human hippocampus and cerebral cortex derived from schizophrenic women. Biological Psychiatry. 32: 1148-63. PMID 1362085 DOI: 10.1016/0006-3223(92)90194-5  0.55
1992 Hall M, Wang Y, Granholm AC, Stevens JO, Young D, Hoffer BJ. Comparison of fetal rabbit brain xenografts to three different strains of athymic nude rats: electrophysiological and immunohistochemical studies of intraocular grafts. Cell Transplantation. 1: 71-82. PMID 1344293  0.691
1992 Hoffer BJ, Leenders KL, Young D, Gerhardt G, Zerbe GO, Bygdeman M, Seiger A, Olson L, Strömberg I, Freedman R. Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Experimental Neurology. 118: 243-52. PMID 1306484 DOI: 10.1016/0014-4886(92)90181-O  0.629
1992 Strömberg I, Sundström E, Almqvist P, Bygdeman M, Johansson M, Hudson J, van Horne C, Bickford P, Hoffer B. Human and Rat Monoaminergic Neuroblasts Grafted to Rats with Unilateral Dopamine Depletions Journal of Neural Transplantation and Plasticity. 3: 229-230. DOI: 10.1155/NP.1992.229  0.714
1991 Giacobini MM, Hoffer B, Olson L. Fibroblast growth factors influence central nervous system development. Evidence from intraocular grafts. Annals of the New York Academy of Sciences. 638: 484-6. PMID 1785824 DOI: 10.1111/j.1749-6632.1991.tb49076.x  0.483
1991 Palmer MR, Henschen A, Trok K, Hudson JL, Hoffer BJ, Olson L. Functional innervation of spinal cord tissue by fetal neocortical grafts in oculo: an electrophysiological study. Experimental Brain Research. 87: 96-107. PMID 1756836 DOI: 10.1007/BF00228510  0.509
1991 Giacobini MM, Hoffer BJ, Zerbe G, Olson L. Acidic and basic fibroblast growth factors augment growth of fetal brain tissue grafts. Experimental Brain Research. 86: 73-81. PMID 1721872 DOI: 10.1007/Bf00231041  0.483
1991 Hoffer BJ, Olson L. Ethical issues in brain-cell transplantation. Trends in Neurosciences. 14: 384-8. PMID 1721747 DOI: 10.1016/0166-2236(91)90168-T  0.483
1990 Palmer MR, Eriksdotter-Nilsson M, Bygdeman M, Stieg P, Strömberg I, Olson L, Seiger A, Hoffer BJ, Granholm AC. Electrophysiologic effects of ethanol in human brain xenografts in oculo: antagonism by Ro15-4513. The Journal of Pharmacology and Experimental Therapeutics. 254: 1100-6. PMID 2395107  0.751
1990 Giacobini MM, Olson L, Hoffer BJ, Sara VR. Truncated IGF-1 exerts trophic effects on fetal brain tissue grafts. Experimental Neurology. 108: 33-7. PMID 2318286 DOI: 10.1016/0014-4886(90)90004-C  0.483
1990 van Horne CG, Bement S, Hoffer BJ, Gerhardt GA. Multichannel semiconductor-based electrodes for in vivo electrochemical and electrophysiological studies in rat CNS. Neuroscience Letters. 120: 249-52. PMID 2293112 DOI: 10.1016/0304-3940(90)90051-A  0.439
1990 Strömberg I, Ebendal T, Olson L, Hoffer B. Chromaffin grafts: survival and nerve fiber formation as a function of donor age, nerve growth factor and host sympathetic denervation. Progress in Brain Research. 82: 87-94. PMID 2290979 DOI: 10.1016/S0079-6123(08)62594-7  0.483
1990 Olson L, Ayer-LeLievre C, Ebendal T, Eriksdotter-Nilsson M, Ernfors P, Henschen A, Hoffer B, Giacobini M, Mouton P, Palmer M. Grafts, growth factors and grafts that make growth factors. Progress in Brain Research. 82: 55-66. PMID 2290958 DOI: 10.1016/S0079-6123(08)62590-X  0.54
1990 Freedman R, Olson L, Hoffer BJ. Toxic effects of lead on neuronal development and function. Environmental Health Perspectives. 89: 27-33. PMID 2088752 DOI: 10.1289/Ehp.908927  0.548
1990 van Horne CG, Mahalik T, Hoffer B, Bygdeman M, Almqvist P, Stieg P, Seiger A, Olson L, Strömberg I. Behavioral and electrophysiological correlates of human mesencephalic dopaminergic xenograft function in the rat striatum. Brain Research Bulletin. 25: 325-34. PMID 1977499 DOI: 10.1016/0361-9230(90)90078-E  0.587
1990 Wittenberg WL, Van Horne CG, Stromberg I, Hoffer BJ. Functional enhancement of intrastriatal fetal dopamine cell grafts by the cotransplantation of peripheral nerve tissue in a rat model of Parkinson's disease Surgical Forum. 41: 502-504.  0.635
1989 Lärkfors L, Ebendal T, Whittemore SR, Persson H, Hoffer B, Olson L. Developmental appearance of nerve growth factor in the rat brain: significant deficits in the aged forebrain. Progress in Brain Research. 78: 27-31. PMID 3247429 DOI: 10.1016/S0079-6123(08)60262-9  0.568
1989 Gerhardt GA, Friedemann M, Brodie MS, Vickroy TW, Gratton AP, Hoffer BJ, Rose GM. The effects of cholecystokinin (CCK-8) on dopamine-containing nerve terminals in the caudate nucleus and nucleus accumbens of the anesthetized rat: an in vivo electrochemical study. Brain Research. 499: 157-63. PMID 2804664 DOI: 10.1016/0006-8993(89)91146-3  0.704
1989 Lindvall O, Rehncrona S, Brundin P, Gustavii B, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC, Frackowiak R, Marsden D, Johnels B, Steg G, Freedman R, ... Hoffer BJ, et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. Archives of Neurology. 46: 615-31. PMID 2786405 DOI: 10.1001/Archneur.1989.00520420033021  0.526
1989 Gratton A, Hoffer BJ, Gerhardt GA. In vivo electrochemical studies of monoamine release in the medial prefrontal cortex of the rat. Neuroscience. 29: 57-64. PMID 2710348 DOI: 10.1016/0306-4522(89)90332-1  0.439
1989 Mahalik TJ, Strömberg I, Gerhardt GA, Granholm AC, Seiger A, Bygdeman M, Olson L, Hoffer BJ, Finger TE. Human ventral mesencephalic xenografts to the catecholamine-depleted striata of athymic rats: ultrastructure and immunocytochemistry. Synapse (New York, N.Y.). 4: 19-29. PMID 2570467 DOI: 10.1002/syn.890040104  0.799
1989 Eriksdotter-Nilsson M, Gerhardt G, Seiger A, Hoffer B, Granholm AC. Multiple changes in noradrenergic mechanisms in the coeruleo-hippocampal pathway during aging. Structural and functional correlates in intraocular double grafts. Neurobiology of Aging. 10: 117-24. PMID 2542818 DOI: 10.1016/0197-4580(89)90020-1  0.72
1989 Stromberg I, Almqvist P, Bygdeman M, Finger T, Gerhardt G, Granholm A, Mahalik T, Seiger A, Olson L, Hoffer B. Human fetal mesencephalic tissue grafted to dopamine-denervated striatum of athymic rats: light- and electron-microscopical histochemistry and in vivo chronoamperometric studies The Journal of Neuroscience. 9: 614-624. DOI: 10.1523/JNEUROSCI.09-02-00614.1989  0.637
1988 Hoffer BJ, Granholm AC, Stevens JO, Olson L. Catecholamine-containing grafts in parkinsonism: past and present. Clinical Research. 36: 189-95. PMID 3286096  0.731
1988 Gratton A, Hoffer BJ, Gerhardt GA. Effects of electrical stimulation of brain reward sites on release of dopamine in rat: an in vivo electrochemical study. Brain Research Bulletin. 21: 319-24. PMID 3263894 DOI: 10.1016/0361-9230(88)90247-X  0.463
1988 Hoffer B, Bickford-Wimer P, Bygdeman M, Granholm AC, Olson L, Seiger A, Stevens J, Strömberg I. Electrophysiological studies of human cerebral and cerebellar cortical tissue grafted to the anterior eye chamber of athymic rodents. Progress in Brain Research. 78: 591-7. PMID 3247454 DOI: 10.1016/S0079-6123(08)60335-0  0.74
1988 Olson L, Strömberg I, Bygdeman M, Henschen A, Hoffer B, Granholm L, Almqvist P, Dahl D, Oertel W, Seiger A. Human fetal cortices and spinal cord transplanted to the anterior chamber of immunodeficient nude rats: immunohistochemical studies. Progress in Brain Research. 78: 583-90. PMID 3247453 DOI: 10.1016/S0079-6123(08)60334-9  0.483
1988 Seiger A, Bygdeman M, Goldstein M, Almqvist P, Hoffer B, Strömberg I, Olson L. Human fetal catecholamine-containing tissues grafted intraocularly and intracranially to immuno-compromised rodent hosts. Progress in Brain Research. 78: 449-55. PMID 3247442 DOI: 10.1016/S0079-6123(08)60317-9  0.483
1988 Gratton A, Hoffer BJ, Gerhardt GA, Wise RA. Potentiation of morphine-elicited circling by dopaminergic uptake blockade. Pharmacology, Biochemistry, and Behavior. 30: 1077-9. PMID 3227032 DOI: 10.1016/0091-3057(88)90142-6  0.437
1988 Granholm AC, Gerhardt GA, Moore E, Eriksdotter-Nilsson M, Nylén P, Johnson AC, Henschen A, Shirley MA, Palmer MR, Hoffer BJ. Toluene exposure during maturation of intraocular brain tissue transplants: alterations of host and graft cerebellar Purkinje neuron function and sensitivity to norepinephrine. Toxicology and Applied Pharmacology. 96: 296-304. PMID 3194916 DOI: 10.1016/0041-008X(88)90088-9  0.748
1988 Strömberg I, Almqvist P, Bygdeman M, Finger TE, Gerhardt G, Granholm AC, Mahalik TJ, Seiger A, Hoffer B, Olson L. Intracerebral xenografts of human mesencephalic tissue into athymic rats: immunochemical and in vivo electrochemical studies. Proceedings of the National Academy of Sciences of the United States of America. 85: 8331-4. PMID 3186728 DOI: 10.1073/Pnas.85.21.8331  0.812
1988 Lindvall O, Rehncrona S, Gustavii B, Brundin P, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC, Frackowiak R, Marsden CD, Johnels B, Steg G, Freedman R, ... Hoffer BJ, et al. Fetal dopamine-rich mesencephalic grafts in Parkinson's disease. Lancet. 2: 1483-4. PMID 2904587 DOI: 10.1016/S0140-6736(88)90950-6  0.528
1987 Granholm AC, Gerhardt GA, Eriksdotter-Nilsson M, Bickford-Wimer PC, Palmer MR, Seiger A, Olson L, Hoffer BJ. Age-related changes in cerebellar noradrenergic pre- and postsynaptic mechanisms: intrinsic vs extrinsic determinants evaluated with brain grafts in oculo. Brain Research. 423: 71-8. PMID 3676821 DOI: 10.1016/0006-8993(87)90826-2  0.785
1987 Gerhardt GA, Rose GM, Hoffer BJ. In vivo electrochemical demonstration of potassium-evoked monoamine release from rat cerebellum. Brain Research. 413: 327-35. PMID 3607482 DOI: 10.1016/0006-8993(87)91024-9  0.424
1987 Hall ME, Granholm AC, Stevens JO, Hoffer BJ. Myocardium and cortex cerebri xenografts transplanted into the anterior chamber of the eye of athymic rats: a morphologic and electrophysiologic profile. Neuroscience Letters. 75: 89-94. PMID 3554011 DOI: 10.1016/0304-3940(87)90081-4  0.666
1987 Bickford-Wimer P, Granholm AC, Bygdeman M, Hoffer B, Olson L, Seiger A, Strömberg I. Human fetal cerebellar and cortical tissue transplanted to the anterior eye chamber of athymic rats: electrophysiological and structural studies. Proceedings of the National Academy of Sciences of the United States of America. 84: 5957-61. PMID 3475712 DOI: 10.1073/PNAS.84.16.5957  0.754
1987 Hoffer BJ, Olson L, Palmer MR. Toxic effects of lead in the developing nervous system: in oculo experimental models. Environmental Health Perspectives. 74: 169-75. PMID 3319551 DOI: 10.1289/Ehp.8774169  0.572
1987 Hoffer BJ, Gerhardt GA, Rose GM, Strömberg I, Olson L. Voltammetric analysis of nigral graft function. Annals of the New York Academy of Sciences. 495: 510-27. PMID 3111328 DOI: 10.1111/j.1749-6632.1987.tb23697.x  0.662
1986 Rose GM, Gerhardt GA, Conboy GL, Hoffer BJ. Age-related alterations in monoamine release from rat striatum: an in vivo electrochemical study. Neurobiology of Aging. 7: 77-82. PMID 3960266 DOI: 10.1016/0197-4580(86)90143-0  0.452
1986 Gerhardt GA, Rose GM, Hoffer BJ. Release of monoamines from striatum of rat and mouse evoked by local application of potassium: evaluation of a new in vivo electrochemical technique. Journal of Neurochemistry. 46: 842-50. PMID 3950610 DOI: 10.1111/j.1471-4159.1986.tb13048.x  0.445
1986 Oskarsson A, Olson L, Palmer MR, Lind B, Björklund H, Hoffer B. Increased lead concentration in brain and potentiation of lead-induced neuronal depression in rats after combined treatment with lead and disulfiram. Environmental Research. 41: 623-32. PMID 3780656 DOI: 10.1016/S0013-9351(86)80156-6  0.555
1986 Wang Y, Pang K, Jacobson AE, Lessor R, Rice KC, Hoffer B. Interactions of phencyclidine with hippocampal circuitry: Evidence for neuronal heterogeneity Pharmacology, Biochemistry and Behavior. 24: 1403-1407. PMID 3725842 DOI: 10.1016/0091-3057(86)90202-9  0.56
1986 Bickford PC, Hoffer BJ, Freedman R. Diminished interaction of norepinephrine with climbing fiber inputs to cerebellar Purkinje neurons in aged Fischer 344 rats. Brain Research. 385: 405-10. PMID 3022875 DOI: 10.1016/0006-8993(86)91092-9  0.535
1985 Bickford PC, Hoffer BJ, Freedman R. Interaction of norepinephrine with Purkinje cell responses to cerebellar afferent inputs in aged rats. Neurobiology of Aging. 6: 89-94. PMID 4022233 DOI: 10.1016/0197-4580(85)90023-5  0.541
1985 Olson L, Backlund EO, Freed W, Herrera-Marschitz M, Hoffer B, Seiger A, Strömberg I. Transplantation of monoamine-producing cell systems in oculo and intracranially: experiments in search of a treatment for Parkinson's Disease. Annals of the New York Academy of Sciences. 457: 105-26. PMID 3913358 DOI: 10.1111/j.1749-6632.1985.tb20801.x  0.483
1985 Hoffer BJ, Dunwiddie TV. Braingrafts: Potential therapy in neurodegenerative diseases and in understanding normal aging in the CNS Neurobiology of Aging. 6: 162-163. DOI: 10.1016/0197-4580(85)90038-7  0.497
1984 Palmer MR, Olson L, Dunwiddie TV, Hoffer BJ, Seiger A. Neonatal cerebellectomy alters ethanol-induced sleep time of short sleep but not long sleep mice. Pharmacology, Biochemistry, and Behavior. 20: 153-9. PMID 6694995 DOI: 10.1016/0091-3057(84)90116-3  0.634
1984 Bickford PC, Mosimann WF, Hoffer BJ, Freedman R. Effects of the selective noradrenergic neurotoxin DSP4 on cerebellar Purkinje neuron electrophysiology. Life Sciences. 34: 731-41. PMID 6422177 DOI: 10.1016/0024-3205(84)90380-1  0.559
1984 Björklund H, Bickford P, Dahl D, Hoffer B, Olson L. Intracranial cerebellar grafts: intermediate filament immunohistochemistry and electrophysiology. Experimental Brain Research. 55: 372-85. PMID 6378650 DOI: 10.1007/Bf00237288  0.631
1984 Björklund H, Hoffer B, Olson L, Palmer M, Seiger A. Enkephalin immunoreactivity in iris nerves: distribution in normal and grafted irides, persistence and enhanced fluorescence after denervations. Histochemistry. 80: 1-7. PMID 6365850 DOI: 10.1007/BF00492763  0.494
1984 Palmer MR, Björklund H, Taylor DA, Seiger A, Olson L, Hoffer BJ. Chronic lead exposure of the developing brain: electrophysiological abnormalities of cerebellar Purkinje neurons. Neurotoxicology. 5: 149-66. PMID 6151635  0.379
1984 Gerhardt GA, Palmer MR, Seiger A, Adams RN, Olson L, Hoffer BJ. Adrenergic transmission in hippocampus-locus coeruleus double grafts in oculo: demonstration by in vivo electrochemical detection. Brain Research. 306: 319-25. PMID 6087976 DOI: 10.1016/0006-8993(84)90381-0  0.716
1983 Björklund H, Palmer MR, Lind B, Hoffer BJ, Olson L. Postnatal lead exposure alters spontaneous cerebellar Purkinje neuron discharge. Environmental Research. 31: 448-59. PMID 6884303 DOI: 10.1016/0013-9351(83)90023-3  0.528
1983 Björklund H, Seiger A, Hoffer B, Olson L. Trophic effects of brain areas on the developing cerebral cortex: I. Growth and histological organization of intraocular grafts. Brain Research. 282: 131-40. PMID 6831236 DOI: 10.1016/0165-3806(83)90091-3  0.483
1983 Hoffer B, Freed W, Olson L, Wyatt RJ. Transplantation of dopamine-containing tissues to the central nervous system Clinical Neurosurgery. 31: 404-416. PMID 6687303 DOI: 10.1093/Neurosurgery/31.Cn_Suppl_1.404  0.483
1983 Freed WJ, Ko GN, Niehoff DL, Kuhar MJ, Hoffer BJ, Olson L, Cannon-Spoor HE, Morihisa JM, Wyatt RJ. Normalization of spiroperidol binding in the denervated rat striatum by homologous grafts of substantia nigra. Science (New York, N.Y.). 222: 937-9. PMID 6635666 DOI: 10.1126/SCIENCE.6635666  0.57
1983 Björklund H, Hoffer BJ, Palmer MR, Seiger A, Olson L. Survival and growth of neurons with enkephalin-like immunoreactivity in fetal brain areas grafted to the anterior chamber of the eye. Neuroscience. 10: 1387-98. PMID 6363968 DOI: 10.1016/0306-4522(83)90120-3  0.56
1983 Basile A, Hoffer B, Dunwiddie T. Differential sensitivity of cerebellar purkinje neurons to ethanol in selectivity outbred lines of mice: maintenance in vitro independent of synaptic transmission Brain Research. 264: 69-78. PMID 6303499 DOI: 10.1016/0006-8993(83)91121-6  0.538
1983 Palmer M, Björklund H, Olson L, Hoffer B. Trophic effects of brain areas on the developing cerebral cortex: II. Electrophysiology of intraocular grafts. Brain Research. 282: 141-8. PMID 6131732 DOI: 10.1016/0165-3806(83)90092-5  0.559
1982 Björklund H, Hoffer B, Olson L, Seiger A. Differential morphological changes in sympathetic nerve fibers elicited by lead, cadmium, and mercury. Environmental Research. 26: 69-80. PMID 7297534 DOI: 10.1016/0013-9351(81)90184-5  0.483
1982 Bickford PC, Palmer MR, Hoffer BJ, Freedman R. Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons. Neuropharmacology. 21: 729-32. PMID 7121744 DOI: 10.1016/0028-3908(82)90056-9  0.551
1982 Olson L, Björklund H, Hoffer BJ, Palmer MR, Seiger A. Spinal cord grafts: an intraocular approach to enigmas of nerve growth regulation. Brain Research Bulletin. 9: 519-37. PMID 6293662 DOI: 10.1016/0361-9230(82)90160-5  0.506
1982 Mueller AL, Palmer MR, Hoffer BJ, Dunwiddie TV. Hippocampal noradrenergic responses in vivo and in vitro. Characterization of alpha and beta components. Naunyn-Schmiedeberg's Archives of Pharmacology. 318: 259-66. PMID 6281666 DOI: 10.1007/Bf00501163  0.518
1982 Mueller AL, Kirk KL, Hoffer BJ, Dunwiddie TV. Noradrenergic responses in rat hippocampus: electrophysiological actions of direct- and indirect-acting sympathomimetics in the in vitro slice. The Journal of Pharmacology and Experimental Therapeutics. 223: 599-605. PMID 6128402  0.524
1981 Olson L, Seiger A, Freedman R, Hoffer B. Chromaffine cells can innervate brain tissue: evidence from intraocular double grafts. Experimental Neurology. 70: 414-26. PMID 7428904 DOI: 10.1016/0014-4886(80)90038-2  0.483
1981 Palmer MR, Björklund H, Freedman R, Taylor DA, Marwaha J, Olson L, Seiger A, Hoffer BJ. Permanent impairment of spontaneous Purkinje cell discharge in cerebellar grafts caused by chronic lead exposure. Toxicology and Applied Pharmacology. 60: 431-40. PMID 7292481 DOI: 10.1016/0041-008X(81)90328-8  0.642
1981 Björklund H, Lind B, Piscator M, Hoffer B, Olson L. Lead, zinc, and copper levels in intraocular brain tissue grafts, brain, and blood of lead-exposed rats. Toxicology and Applied Pharmacology. 60: 424-30. PMID 7292480 DOI: 10.1016/0041-008X(81)90327-6  0.483
1981 Bickford PC, Palmer MR, Rice KC, Hoffer BJ, Freedman R. Electrophysiological effects of phencyclidine on rat hippocampal pyramidal neurons. Neuropharmacology. 20: 733-42. PMID 7279144 DOI: 10.1016/0028-3908(81)90221-5  0.546
1981 Wuerthele SM, Freed WJ, Olson L, Morihisa J, Spoor L, Wyatt RJ, Hoffer BJ. Effect of dopamine agonists and antagonists on the electrical activity of substantia nigra neurons transplanted into the lateral ventricle of the rat. Experimental Brain Research. 44: 1-10. PMID 7274357 DOI: 10.1007/Bf00238743  0.483
1981 Freed WJ, Morihisa JM, Spoor E, Hoffer BJ, Olson L, Seiger A, Wyatt RJ. Transplanted adrenal chromaffin cells in rat brain reduce lesion-induced rotational behaviour. Nature. 292: 351-2. PMID 7254334 DOI: 10.1038/292351A0  0.483
1981 Dunwiddie TV, Hoffer BJ, Fredholm BB. Alkylxanthines elevate hippocampal excitability. Evidence for a role of endogenous adenosine. Naunyn-Schmiedeberg's Archives of Pharmacology. 316: 326-30. PMID 6267486 DOI: 10.1007/Bf00501365  0.522
1981 Mueller AL, Hoffer BJ, Dunwiddie TV. Noradrenergic responses in rat hippocampus: evidence for medication by alpha and beta receptors in the in vitro slice. Brain Research. 214: 113-26. PMID 6263414 DOI: 10.1016/0006-8993(81)90442-X  0.518
1980 Björklund H, Olson L, Seiger A, Hoffer B. Chronic lead and brain development: intraocular brain grafts as a method to reveal regional and temporal effects in the central nervous system. Environmental Research. 22: 224-36. PMID 7418681 DOI: 10.1016/0013-9351(80)90134-6  0.483
1980 Taylor D, Freedman R, Seiger A, Olson L, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: II. Electrophysiological evidence from intraocular double grafts. Experimental Brain Research. 39: 289-99. PMID 7398824 DOI: 10.1007/Bf00237118  0.568
1980 Olson L, Seiger A, Taylor D, Freedman R, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: I. Histochemical evidence from intraocular double grafts. Experimental Brain Research. 39: 277-88. PMID 7398823 DOI: 10.1007/Bf00237117  0.582
1980 Dunwiddie T, Mueller A, Palmer M, Stewart J, Hoffer B. Electrophysiological interactions of enkephalins with neuronal circuitry in the rat hippocampus. I. Effects on pyramidal cell activity Brain Research. 184: 311-330. PMID 7353158 DOI: 10.1016/0006-8993(80)90801-X  0.556
1980 Hoffer B, Taylor D, Baker R, Deitrich R, Seiger A, Olson L. Ethanol withdrawal seizures in hippocampus transplanted to the anterior chamber of the eye. Life Sciences. 26: 239-44. PMID 7189008 DOI: 10.1016/0024-3205(80)90299-4  0.584
1980 Geller HM, Hoffer BJ, Taylor DA. Electrophysiological actions of benzodiazepines. Federation Proceedings. 39: 3016-23. PMID 6252064  0.389
1980 Dunwiddie TV, Hoffer BJ. Adenine nucleotides and synaptic transmission in the in vitro rat hippocampus. British Journal of Pharmacology. 69: 59-68. PMID 6247005 DOI: 10.1111/j.1476-5381.1980.tb10883.x  0.518
1979 Perlow MJ, Freed WJ, Hoffer BJ, Seiger A, Olson L, Wyatt RJ. Brain grafts reduce motor abnormalities produced by destruction of nigrostriatal dopamine system. Science (New York, N.Y.). 204: 643-7. PMID 571147 DOI: 10.1126/Science.571147  0.483
1979 Meuller AL, Dunwiddie TV, Palmer MR, Lee HK, Stewart JM, Hoffer BJ. Enkephalins and hippocampal neuronal circuits. Proceedings of the Western Pharmacology Society. 22: 471-4. PMID 515091  0.551
1979 Freedman R, Taylor DA, Seiger A, Olson L, Hoffer BJ. Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye: modulation by cholinergic and adrenergic input. Annals of Neurology. 6: 281-95. PMID 233411 DOI: 10.1002/Ana.410060402  0.45
1979 Smellie FW, Daly JW, Dunwiddie TV, Hoffer BJ. The dextro and levorotatory isomers of N-phenylisopropyladenosine: stereospecific effects on cyclic AMP-formation and evoked synaptic responses in brain slices. Life Sciences. 25: 1739-48. PMID 231163 DOI: 10.1016/0024-3205(79)90477-6  0.544
1979 Lee HK, Dunwiddie TV, Hoffer BJ. Interaction of diazepam with synaptic transmission in the in vitro rat hippocampus. Naunyn-Schmiedeberg's Archives of Pharmacology. 309: 131-6. PMID 230418 DOI: 10.1007/BF00501220  0.558
1978 Taylor D, Seiger A, Freedman R, Olson L, Hoffer B. Electrophysiological analysis reinnervation of transplants in the anterior chamber of the eye by the autonomic ground plexus of the iris. Proceedings of the National Academy of Sciences of the United States of America. 75: 1009-12. PMID 273212 DOI: 10.1073/Pnas.75.2.1009  0.532
1978 Palmer MR, Morris DH, Taylor DA, Stewart JM, Hoffer BJ. Electrophysiological effects of enkephalin analogs in rat cortex. Life Sciences. 23: 851-60. PMID 212657  0.398
1978 Geller HM, Taylor DA, Hoffer BJ. Benzodiazepines and central inhibitory mechanisms. Naunyn-Schmiedeberg's Archives of Pharmacology. 304: 81-8. PMID 30047 DOI: 10.1007/BF00495542  0.432
1977 Hoffer BJ, Seiger A, Taylor D, Olson L, Freedman R. Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye I. Characterization of seizures, interictal spikes, and synchronous activity. Experimental Neurology. 54: 233-50. PMID 838015 DOI: 10.1016/0014-4886(77)90267-9  0.584
1977 Olson L, Freedman R, Seiger A, Hoffer B. Electrophysiology and cytology of hippocampal formation transplants in the anterior chamber of the eye. I. Intrinsic organization. Brain Research. 119: 87-106. PMID 830386 DOI: 10.1016/0006-8993(77)90093-2  0.506
1977 Woodward DJ, Seiger A, Olson L, Hoffer BJ. Intrinsic and extrinsic determinants of dendritic development as revealed by Golgi studies of cerebellar and hippocampal transplants in oculo. Experimental Neurology. 57: 984-98. PMID 72681 DOI: 10.1016/0014-4886(77)90122-4  0.555
1976 Hoffer B, Olson L, Seiger A, Bloom F. Formation of a functional adrenergic input to intraocular cerebellar grafts: ingrowth of inhibitory sympathetic fibers. Journal of Neurobiology. 6: 565-85. PMID 1185191 DOI: 10.1002/NEU.480060604  0.626
1976 Siggins GR, Hoffer BJ, Bloom FE, Ungerstedt U. Cytochemical and electrophysiological studies of dopamine in the caudate nucleus. Research Publications - Association For Research in Nervous and Mental Disease. 55: 227-48. PMID 188086  0.498
1975 Hoffer B, Seiger A, Ljungberg T, Olson L. Electrophysiological and cytological studies of brain homografts in the anterior chamber of the eye: maturation of cerebellar cortex in oculo. Brain Research. 79: 165-84. PMID 4424939 DOI: 10.1016/0006-8993(74)90409-0  0.483
1975 Hoffer BJ, Siggins GR. Electrophysiological techniques for the study of hormone action in the central nervous system. Methods in Enzymology. 39: 429-40. PMID 239301 DOI: 10.1016/S0076-6879(75)39038-1  0.498
1975 Bloom FE, Siggins GR, Hoffer BJ, Segal M, Oliver AP. Cyclic nucleotdides in the central synaptic actions of catecholamines. Advances in Cyclic Nucleotide Research. 5: 603-18. PMID 165689  0.498
1975 Shoemaker WJ, Balentine LT, Siggins GR, Hoffer BJ, Henriksen SJ, Bloom FE. Characteristics of the release of adenosine 3':5'-monophosphate from micropipets by microiontophoresis. Journal of Cyclic Nucleotide Research. 1: 97-106. PMID 4474  0.664
1974 Siggins GR, Hoffer BJ, Ungerstedt U. Electrophysiological evidence for involvement of cyclic adenosine monophosphate in dopamine responses of caudate neurons. Life Sciences. 15: 779-92. PMID 4378085 DOI: 10.1016/0024-3205(74)90516-5  0.577
1974 Bloom FE, Siggins GR, Hoffer BJ. Interpreting the failures to confirm the depression of cerebellar Purkinje cells by cyclic AMP. Science (New York, N.Y.). 185: 627-9. PMID 4366788 DOI: 10.1126/science.185.4151.627  0.569
1974 Bloom FE, Hoffer BJ. Norepinephrine as a central synaptic transmitter Biochemical Pharmacology. 23: 517-522. DOI: 10.1016/0006-2952(74)90073-2  0.417
1973 Bloom FE, Chu N, Hoffer BJ, Nelson CN, Siggins GR. Studies on the function of central noradrenergic neurons. Neurosciences Research. 5: 53-72. PMID 4366084 DOI: 10.1016/B978-0-12-512505-5.50009-4  0.64
1973 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Activation of the pathway from locus coeruleus to rat cerebellar Purkinje neurons: pharmacological evidence of noradrenergic central inhibition. The Journal of Pharmacology and Experimental Therapeutics. 184: 553-69. PMID 4347049  0.498
1973 Siggins GR, Battenberg EF, Hoffer BJ, Bloom FE, Steiner AL. Noradrenergic stimulation of cyclic adenosine monophosphate in rat Purkinje neurons: an immunocytochemical study. Science (New York, N.Y.). 179: 585-8. PMID 4346826 DOI: 10.1126/Science.179.4073.585  0.653
1973 Nelson CN, Hoffer BJ, Chu NS, Bloom FE. Cytochemical and pharmacological studies on polysensory neurons in the primate frontal cortex. Brain Research. 62: 115-33. PMID 4148775 DOI: 10.1016/0006-8993(73)90623-9  0.437
1973 Bloom F, Hoffer B. Norepinephrine as a central synaptic transmitter Life Sciences. 13: ix-x. DOI: 10.1016/0024-3205(73)90241-5  0.365
1972 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Cyclic AMP-mediated adrenergic synapses to cerebellar Purkinje cells. Advances in Cyclic Nucleotide Research. 1: 411-23. PMID 4353180  0.498
1972 Bloom FE, Hoffer BJ, Battenberg ER, Siggins GR, Steiner AL, Parker CW, Wedner HJ. Adenosine 3',5'-monophosphate is localized in cerebellar neurons: immunofluorescence evidence. Science (New York, N.Y.). 177: 436-8. PMID 4339615 DOI: 10.1126/Science.177.4047.436  0.645
1972 Bloom FE, Hoffer BJ, Siggins GR. Norepinephrine mediated cerebellar synapses: a model system for neuropsychopharmacology. Biological Psychiatry. 4: 157-77. PMID 4337435  0.498
1972 Bloom FE, Hoffer BJ, Siggins GR, Barker JL, Nicoll RA. Effects of serotonin on central neurons: microiontophoretic administration. Federation Proceedings. 31: 97-106. PMID 4333253  0.564
1972 Wedner HF, Hoffer BJ, Battenberg EB, Steiner AL, Parker CW, Bloom FE. A method for detecting intracellular cyclic adenosine monophosphate by immunofluorescence. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 20: 293-5. PMID 4113297 DOI: 10.1177/20.4.293  0.335
1971 Bloom FE, Hoffer BJ, Siggins GR. Studies on norepinephrine-containing afferents to Purkinje cells of art cerebellum. I. Localization of the fibers and their synapses. Brain Research. 25: 501-21. PMID 5544323 DOI: 10.1016/0006-8993(71)90457-4  0.596
1971 Siggins G, Hoffer B, Bloom F. Prostaglandin-norepinephrine interactions in brain: microelectrophoretic and histochemical correlates. Annals of the New York Academy of Sciences. 180: 302-23. PMID 5286100 DOI: 10.1111/J.1749-6632.1971.Tb53199.X  0.591
1971 Hoffer BJ, Neff NH, Siggins GR. Microiontophoretic release of norepinephrine from micropipettes. Neuropharmacology. 10: 175-80. PMID 5093958 DOI: 10.1016/0028-3908(71)90038-4  0.498
1971 Siggins GR, Hoffer BJ, Oliver AP, Bloom FE. Activation of a central noradrenergic projection to cerebellum. Nature. 233: 481-3. PMID 4939543 DOI: 10.1038/233481A0  0.631
1971 Hoffer BJ, Siggins GR, Bloom FE. Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. II. Sensitivity of Purkinje cells to norepinephrine and related substances administered by microiontophoresis. Brain Research. 25: 523-34. PMID 4395919 DOI: 10.1016/0006-8993(71)90458-6  0.636
1971 Godfraind JM, Pumain R, Siggins GR, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate and norepinephrine: effect on purkinje cells in rat cerebellar cortex. Science (New York, N.Y.). 174: 1257-9. PMID 4332286 DOI: 10.1126/Science.174.4015.1257  0.615
1971 Lapham LW, Lentz RD, Woodward DJ, Hoffer BJ, Herman CJ. Postnatal development of tetraploid DNA content in the Purkinje neuron of the rat: an aspect of cellular differentiation. Ucla Forum in Medical Sciences. 14: 61-71. PMID 4331240  0.63
1971 Woodward DJ, Hoffer BJ, Siggins GR, Bloom FE. The ontogenetic development of synaptic junctions, synaptic activation and responsiveness to neurotransmitter substances in rat cerebellar purkinje cells. Brain Research. 34: 73-97. PMID 4330971 DOI: 10.1016/0006-8993(71)90352-0  0.617
1971 Hoffer BJ, Siggins GR, Oliver AP, Bloom FE. Cyclic AMP mediation of norepinephrine inhibition in rat cerebellar cortex: a unique class of synaptic responses. Annals of the New York Academy of Sciences. 185: 531-49. PMID 4330518 DOI: 10.1111/J.1749-6632.1971.Tb45279.X  0.606
1971 Woodward DJ, Hoffer BJ, Siggins GR, Oliver AP. Inhibition of Purkinje cells in the frog cerebellum. II. Evidence for GABA as the inhibitory transmitter. Brain Research. 33: 91-100. PMID 4330216 DOI: 10.1016/0006-8993(71)90308-8  0.492
1971 Hoffer BJ, Siggins GR, Woodward DJ, Bloom FE. Spontaneous discharge of Purkinje neurons after destruction of catecholamine-containing afferents by 6-hydroxydopamine. Brain Research. 30: 425-30. PMID 4329214 DOI: 10.1016/0006-8993(71)90095-3  0.65
1971 Siggins GR, Hoffer BJ, Bloom FE. Studies on norepinephrine-containing afferents to Purkinje cells of rat cerebellum. 3. Evidence for mediation of norepinephrine effects by cyclic 3',5'-adenosine monophosphate. Brain Research. 25: 535-53. PMID 4322679 DOI: 10.1016/0006-8993(71)90459-8  0.625
1971 Siggins GR, Oliver AP, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate and norepinephrine: effects on transmembrane properties of cerebellar Purkinje cells. Science (New York, N.Y.). 171: 192-4. PMID 4322158 DOI: 10.1126/Science.171.3967.192  0.613
1970 Hoffer BJ, Siggins GR, Bloom FE. Possible cyclic AMP-mediated adrenergic synapses to rat cerebellar Purkinje cells: combined structural, physiological, and pharmacological analyses. Advances in Biochemical Psychopharmacology. 3: 349-70. PMID 4331463  0.498
1969 Woodward DJ, Hoffer BJ, Lapham LW. Postnatal development of electrical and enzyme histochemical activity in Purkinje cells. Experimental Neurology. 23: 120-39. PMID 5765001 DOI: 10.1016/0014-4886(69)90039-9  0.601
1969 Hoffer BJ, Siggins GR, Bloom FE. Prostaglandins E1 and E2 antagonize norepinephrine effects on cerebellar purkinje cells: microelectrophoretic study. Science (New York, N.Y.). 166: 1418-20. PMID 5350346 DOI: 10.1126/Science.166.3911.1418  0.591
1969 Siggins GR, Hoffer BJ, Bloom FE. Cyclic adenosine monophosphate: possible mediator for norepinephrine effects on cerebellar Purkinje cells. Science (New York, N.Y.). 165: 1018-20. PMID 4308638 DOI: 10.1126/Science.165.3897.1018  0.609
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