Year |
Citation |
Score |
2020 |
Limegrover CS, LeVine H, Izzo NJ, Yurko R, Mozzoni K, Rehak C, Sadlek K, Safferstein H, Catalano SM. Alzheimer's Protection Effect of A673T Mutation May Be Driven by Lower Aβ Oligomer Binding Affinity. Journal of Neurochemistry. PMID 33025581 DOI: 10.1111/jnc.15212 |
0.651 |
|
2019 |
Grundman M, Morgan R, Lickliter JD, Schneider LS, DeKosky S, Izzo NJ, Guttendorf R, Higgin M, Pribyl J, Mozzoni K, Safferstein H, Catalano SM. A phase 1 clinical trial of the sigma-2 receptor complex allosteric antagonist CT1812, a novel therapeutic candidate for Alzheimer's disease. Alzheimer's & Dementia (New York, N. Y.). 5: 20-26. PMID 30723776 DOI: 10.1016/J.Trci.2018.11.001 |
0.644 |
|
2019 |
Schneider LS, Caggiano AO, Grundman M, DeKosky S, Morgan R, Mozzoni K, Izzo NJ, Safferstein H, Catalano S. CLINICAL BIOMARKER EVIDENCE FOR TARGET ENGAGEMENT, REDUCTION OF SYNAPTIC DAMAGE AND DISEASE MODIFICATION IN ALZHEIMER’S PATIENTS TREATED WITH CT1812 Alzheimer's & Dementia. 15: P1603-P1604. DOI: 10.1016/J.Jalz.2019.09.072 |
0.384 |
|
2017 |
Catalano S, Grundman M, Schneider LS, DeKosky S, Morgan R, Guttendorf R, Higgin M, Pribyl J, Mozzoni K, Izzo NJ, Safferstein H. A PHASE 1 SAFETY TRIAL OF THE Aβ OLIGOMER RECEPTOR ANTAGONIST CT1812 Alzheimer's & Dementia. 13: P1570. DOI: 10.1016/J.Jalz.2017.07.730 |
0.461 |
|
2014 |
Izzo NJ, Xu J, Zeng C, Kirk MJ, Mozzoni K, Silky C, Rehak C, Yurko R, Look G, Rishton G, Safferstein H, Cruchaga C, Goate A, Cahill MA, Arancio O, et al. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity. Plos One. 9: e111899. PMID 25390692 DOI: 10.1371/Journal.Pone.0111899 |
0.677 |
|
2014 |
Izzo NJ, Staniszewski A, To L, Fa M, Teich AF, Saeed F, Wostein H, Walko T, Vaswani A, Wardius M, Syed Z, Ravenscroft J, Mozzoni K, Silky C, Rehak C, et al. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits. Plos One. 9: e111898. PMID 25390368 DOI: 10.1371/Journal.Pone.0111898 |
0.674 |
|
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