| Year |
Citation |
Score |
| 2024 |
Grosso Jasutkar H, Wasserlein EM, Ishola A, Litt N, Staniszewski A, Arancio O, Yamamoto A. Adult-onset deactivation of autophagy leads to loss of synapse homeostasis and cognitive impairment, with implications for alzheimer disease. Autophagy. 1-16. PMID 38949671 DOI: 10.1080/15548627.2024.2368335 |
0.382 |
|
| 2024 |
Ribeiro FC, Cozachenco D, Argyrousi EK, Staniszewski A, Wiebe S, Calixtro JD, Soares-Neto R, Al-Chami A, Sayegh FE, Bermudez S, Arsenault E, Cossenza M, Lacaille JC, Nader K, Sun H, ... ... Arancio O, et al. The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38934107 DOI: 10.1002/alz.14034 |
0.314 |
|
| 2023 |
Haut F, Argyrousi EK, Arancio O. Re-Arranging the Puzzle between the Amyloid-Beta and Tau Pathology: An APP-Centric Approach. International Journal of Molecular Sciences. 25. PMID 38203429 DOI: 10.3390/ijms25010259 |
0.333 |
|
| 2023 |
Zuccarello E, Zhang H, Acquarone E, Pham D, Staniszewski A, Deng S, Landry DW, Arancio O, Fiorito J. Optimizing metabolic stability of phosphodiesterase 5 inhibitors: discovery of a potent N-(pyridin-3-ylmethyl)quinoline derivative targeting synaptic plasticity. Bioorganic & Medicinal Chemistry Letters. 129409. PMID 37453616 DOI: 10.1016/j.bmcl.2023.129409 |
0.312 |
|
| 2023 |
Puliatti G, Li Puma DD, Aceto G, Lazzarino G, Acquarone E, Mangione R, D'Adamio L, Ripoli C, Arancio O, Piacentini R, Grassi C. Intracellular accumulation of tau oligomers in astrocytes and their synaptotoxic action rely on Amyloid Precursor Protein Intracellular Domain-dependent expression of Glypican-4. Progress in Neurobiology. 227: 102482. PMID 37321444 DOI: 10.1016/j.pneurobio.2023.102482 |
0.352 |
|
| 2023 |
Falcicchia C, Tozzi F, Gabrielli M, Amoretti S, Masini G, Nardi G, Guglielmo S, Ratto GM, Arancio O, Verderio C, Origlia N. Microglial extracellular vesicles induce Alzheimer's disease-related cortico-hippocampal network dysfunction. Brain Communications. 5: fcad170. PMID 37288314 DOI: 10.1093/braincomms/fcad170 |
0.348 |
|
| 2022 |
Tropea MR, Gulisano W, Vacanti V, Arancio O, Puzzo D, Palmeri A. Nitric oxide/cGMP/CREB pathway and amyloid-beta crosstalk: From physiology to Alzheimer's disease. Free Radical Biology & Medicine. 193: 657-668. PMID 36400326 DOI: 10.1016/j.freeradbiomed.2022.11.022 |
0.393 |
|
| 2022 |
Selles MC, Fortuna JTS, Cercato MC, Santos LE, Domett L, Bitencourt ALB, Carraro MF, Souza AS, Janickova H, Azevedo CV, Campos HC, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, ... ... Arancio O, et al. AAV-mediated neuronal expression of an scFv antibody selective for Aβ oligomers protects synapses and rescues memory in Alzheimer models. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 36369741 DOI: 10.1016/j.ymthe.2022.11.002 |
0.373 |
|
| 2022 |
Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM, Sulzer D, Goldman JE, Tang G. Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex. Cell Reports. 40: 111085. PMID 35858542 DOI: 10.1016/j.celrep.2022.111085 |
0.302 |
|
| 2022 |
Gabrielli M, Prada I, Joshi P, Falcicchia C, D'Arrigo G, Rutigliano G, Battocchio E, Zenatelli R, Tozzi F, Radeghieri A, Arancio O, Origlia N, Verderio C. Microglial large extracellular vesicles propagate early synaptic dysfunction in Alzheimer's disease. Brain : a Journal of Neurology. PMID 35254410 DOI: 10.1093/brain/awac083 |
0.411 |
|
| 2021 |
Tropea MR, Li Puma DD, Melone M, Gulisano W, Arancio O, Grassi C, Conti F, Puzzo D. Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology. Progress in Neurobiology. 102154. PMID 34453977 DOI: 10.1016/j.pneurobio.2021.102154 |
0.405 |
|
| 2021 |
Gnanaprakash M, Staniszewski A, Zhang H, Pitstick R, Kavanaugh MP, Arancio O, Nicholls RE. Leucine Carboxyl Methyltransferase 1 Overexpression Protects Against Cognitive and Electrophysiological Impairments in Tg2576 APP Transgenic Mice. Journal of Alzheimer's Disease : Jad. PMID 33459709 DOI: 10.3233/JAD-200462 |
0.31 |
|
| 2020 |
Arancio O. What Does the APP Family Do in the Brain? Neuron. 108: 583-585. PMID 33242425 DOI: 10.1016/j.neuron.2020.11.003 |
0.329 |
|
| 2020 |
Falcicchia C, Tozzi F, Arancio O, Watterson DM, Origlia N. Involvement of p38 MAPK in Synaptic Function and Dysfunction. International Journal of Molecular Sciences. 21. PMID 32781522 DOI: 10.3390/Ijms21165624 |
0.488 |
|
| 2020 |
Puzzo D, Argyrousi EK, Staniszewski A, Zhang H, Calcagno E, Zuccarello E, Acquarone E, Fà M, Li Puma DD, Grassi C, D'Adamio L, Kanaan NM, Fraser PE, Arancio O. Tau is not necessary for amyloid-beta-induced synaptic and memory impairments. The Journal of Clinical Investigation. PMID 32544084 DOI: 10.1172/Jci137040 |
0.499 |
|
| 2020 |
Staniszewski A, Zhang H, Asam K, Pitstick R, Kavanaugh MP, Arancio O, Nicholls RE. Reduced expression of the PP2A methylesterase, PME-1, or the PP2A methyltransferase, LCMT-1, alter sensitivity to beta-amyloid induced cognitive and electrophysiological impairments in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32341098 DOI: 10.1523/Jneurosci.2983-19.2020 |
0.476 |
|
| 2020 |
Zuccarello E, Acquarone E, Calcagno E, Argyrousi EK, Deng SX, Landry DW, Arancio O, Fiorito J. Development of novel phosphodiesterase 5 inhibitors for the therapy of alzheimer's disease. Biochemical Pharmacology. 113818. PMID 31978378 DOI: 10.1016/J.Bcp.2020.113818 |
0.403 |
|
| 2019 |
Kelschenbach J, He H, Kim BH, Borjabad A, Gu CJ, Chao W, Do M, Sharer LR, Zhang H, Arancio O, Potash MJ, Volsky DJ. Efficient Expression of HIV in Immunocompetent Mouse Brain Reveals a Novel Nonneurotoxic Viral Function in Hippocampal Synaptodendritic Injury and Memory Impairment. Mbio. 10. PMID 31266862 DOI: 10.1128/Mbio.00591-19 |
0.329 |
|
| 2019 |
Acquarone E, Argyrousi EK, van den Berg M, Gulisano W, Fà M, Staniszewski A, Calcagno E, Zuccarello E, D'Adamio L, Deng SX, Puzzo D, Arancio O, Fiorito J. Synaptic and memory dysfunction induced by tau oligomers is rescued by up-regulation of the nitric oxide cascade. Molecular Neurodegeneration. 14: 26. PMID 31248451 DOI: 10.1186/S13024-019-0326-4 |
0.469 |
|
| 2019 |
Gulisano W, Melone M, Ripoli C, Rosaria Tropea M, Li Puma DD, Giunta S, Cocco S, Marcotulli D, Origlia N, Palmeri A, Arancio O, Conti F, Grassi C, Puzzo D. Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31127002 DOI: 10.1523/Jneurosci.0163-19.2019 |
0.526 |
|
| 2019 |
Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, ... ... Arancio O, et al. Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models. Nature Medicine. 25: 165-175. PMID 30617325 DOI: 10.1038/S41591-018-0275-4 |
0.458 |
|
| 2019 |
Lourenco MV, Arancio O, Ferreira ST, De Felice FG. P2-162: EXERCISE-LINKED FNDC5/IRISIN CORRECTS SYNAPTIC PLASTICITY AND MEMORY DEFECTS IN MOUSE MODELS OF ALZHEIMER'S DISEASE Alzheimer's & Dementia. 15: P637-P638. DOI: 10.1016/J.Jalz.2019.06.2569 |
0.417 |
|
| 2019 |
Sellés MC, Fortuna J, Cercato M, Bitencourt A, Souza A, Prado V, Prado M, Sebollela A, Arancio O, Klein W, De Felice F, Jerusalinsky D, Ferreira S. Neuronal expression of NUsc1, a single-chain variable fragment antibody against Ab oligomers, protects synapses and rescues memory in Alzheimer's disease models Ibro Reports. 6: S497. DOI: 10.1016/J.Ibror.2019.07.1558 |
0.409 |
|
| 2018 |
Biundo F, d'Abramo C, Tambini MD, Zhang H, Del Prete D, Vitale F, Giliberto L, Arancio O, D'Adamio L. Correction: Abolishing Tau cleavage by caspases at Aspartate causes memory/synaptic plasticity deficits and pre-pathological Tau alterations. Translational Psychiatry. 8: 172. PMID 30171180 DOI: 10.1038/S41398-018-0188-5 |
0.443 |
|
| 2018 |
Gulisano W, Melone M, Li Puma DD, Tropea MR, Palmeri A, Arancio O, Grassi C, Conti F, Puzzo D. The effect of amyloid-β peptide on synaptic plasticity and memory is influenced by different isoforms, concentrations, and aggregation status. Neurobiology of Aging. 71: 51-60. PMID 30092511 DOI: 10.1016/J.Neurobiolaging.2018.06.025 |
0.488 |
|
| 2018 |
Rutigliano G, Stazi M, Arancio O, Watterson DM, Origlia N. An isoform-selective p38α mitogen-activated protein kinase inhibitor rescues early entorhinal cortex dysfunctions in a mouse model of Alzheimer's disease. Neurobiology of Aging. 70: 86-91. PMID 30007168 DOI: 10.1016/J.Neurobiolaging.2018.06.006 |
0.418 |
|
| 2018 |
Teich AF, Sharma E, Barnwell E, Zhang H, Staniszewski A, Utsuki T, Padmaraju V, Mazell C, Tzekou A, Sambamurti K, Arancio O, Maccecchini ML. Translational inhibition of APP by Posiphen: Efficacy, pharmacodynamics, and pharmacokinetics in the APP/PS1 mouse. Alzheimer's & Dementia (New York, N. Y.). 4: 37-45. PMID 29955650 DOI: 10.1016/J.Trci.2017.12.001 |
0.399 |
|
| 2018 |
Argyrousi EK, Staniszewski A, Nicholls RE, Arancio O. Preparation of Tau Oligomers After the Protein Extraction from Bacteria and Brain Cortices. Methods in Molecular Biology (Clifton, N.J.). 1779: 85-97. PMID 29886529 DOI: 10.1007/978-1-4939-7816-8_7 |
0.304 |
|
| 2018 |
Gulisano W, Tropea MR, Arancio O, Palmeri A, Puzzo D. Sub-efficacious doses of phosphodiesterase 4 and 5 inhibitors improve memory in a mouse model of Alzheimer's disease. Neuropharmacology. PMID 29885420 DOI: 10.1016/J.Neuropharm.2018.06.002 |
0.392 |
|
| 2018 |
Gulisano W, Maugeri D, Baltrons MA, Fà M, Amato A, Palmeri A, D'Adamio L, Grassi C, Devanand DP, Honig LS, Puzzo D, Arancio O. Role of Amyloid-β and Tau Proteins in Alzheimer's Disease: Confuting the Amyloid Cascade. Journal of Alzheimer's Disease : Jad. PMID 29865055 DOI: 10.3233/Jad-179935 |
0.468 |
|
| 2018 |
Biundo F, Del Prete D, Zhang H, Arancio O, D'Adamio L. A role for tau in learning, memory and synaptic plasticity. Scientific Reports. 8: 3184. PMID 29453339 DOI: 10.1038/S41598-018-21596-3 |
0.46 |
|
| 2018 |
Fang F, Yu Q, Arancio O, Chen D, Gore SS, Yan SF, Yan SS. RAGE mediates Aβ accumulation in a mouse model of Alzheimer's disease via modulation of β- and γ-secretase activity. Human Molecular Genetics. PMID 29329433 DOI: 10.1093/Hmg/Ddy017 |
0.421 |
|
| 2017 |
Yang S, Pascual-Guiral S, Ponce R, Giménez-Llort L, Baltrons MA, Arancio O, Palacio JR, Clos VM, Yuste VJ, Bayascas JR. Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides. Frontiers in Aging Neuroscience. 9: 435. PMID 29358916 DOI: 10.3389/Fnagi.2017.00435 |
0.403 |
|
| 2017 |
Asam K, Staniszewski A, Zhang H, Melideo SL, Mazzeo A, Voronkov M, Huber KL, Pérez E, Stock M, Stock JB, Arancio O, Nicholls RE. Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer's disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid. Plos One. 12: e0189413. PMID 29253878 DOI: 10.1371/Journal.Pone.0189413 |
0.458 |
|
| 2017 |
Knock E, Matsuzaki S, Takamura H, Satoh K, Rooke G, Han K, Zhang H, Staniszewski A, Katayama T, Arancio O, Fraser PE. SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model. Neurobiology of Disease. 110: 154-165. PMID 29217476 DOI: 10.1016/J.Nbd.2017.11.015 |
0.466 |
|
| 2017 |
Knock E, Matsuzaki S, Takamura H, Satoh K, Rooke G, Han K, Zhang H, Staniszewski A, Katayama T, Arancio O, Fraser PE. SUMO1 impact on Alzheimer disease pathology in an amyloid-depositing mouse model. Neurobiology of Disease. 110: 154-165. PMID 29217476 DOI: 10.1016/j.nbd.2017.11.015 |
0.363 |
|
| 2017 |
Ortiz-Virumbrales M, Moreno CL, Kruglikov I, Marazuela P, Sproul A, Jacob S, Zimmer M, Paull D, Zhang B, Schadt EE, Ehrlich ME, Tanzi RE, Arancio O, Noggle S, Gandy S. CRISPR/Cas9-Correctable mutation-related molecular and physiological phenotypes in iPSC-derived Alzheimer's PSEN2 (N141I) neurons. Acta Neuropathologica Communications. 5: 77. PMID 29078805 DOI: 10.1186/S40478-017-0475-Z |
0.352 |
|
| 2017 |
Fiorito J, Vendome J, Saeed F, Staniszewski A, Zhang H, Yan S, Deng SX, Arancio O, Landry DW. Identification of a Novel 1,2,3,4-tetrahydrobenzo[b][1,6]naphthyridine Analog as a Potent Phosphodiesterase 5 Inhibitor with Improved Aqueous Solubility for the Treatment of Alzheimer's Disease. Journal of Medicinal Chemistry. PMID 28985058 DOI: 10.1021/Acs.Jmedchem.7B00979 |
0.334 |
|
| 2017 |
Martín-Maestro P, Gargini R, A Sproul A, García E, Antón LC, Noggle S, Arancio O, Avila J, García-Escudero V. Mitophagy Failure in Fibroblasts and iPSC-Derived Neurons of Alzheimer's Disease-Associated Presenilin 1 Mutation. Frontiers in Molecular Neuroscience. 10: 291. PMID 28959184 DOI: 10.3389/Fnmol.2017.00291 |
0.396 |
|
| 2017 |
Biundo F, d'Abramo C, Tambini MD, Zhang H, Del Prete D, Vitale F, Giliberto L, Arancio O, D'Adamio L. Abolishing Tau cleavage by caspases at Aspartate(421) causes memory/synaptic plasticity deficits and pre-pathological Tau alterations. Translational Psychiatry. 7: e1198. PMID 28786980 DOI: 10.1038/Tp.2017.165 |
0.441 |
|
| 2017 |
Puzzo D, Piacentini R, Fa' M, Gulisano W, Li Puma DD, Staniszewski A, Zhang H, Tropea MR, Cocco S, Palmeri A, Fraser P, D'Adamio L, Grassi C, Arancio O. LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent. Elife. 6. PMID 28696204 DOI: 10.7554/Elife.26991 |
0.5 |
|
| 2017 |
Manassero G, Guglielmotto M, Monteleone D, Vasciaveo V, Butenko O, Tamagno E, Arancio O, Tabaton M. Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice. Journal of Alzheimer's Disease : Jad. PMID 28671129 DOI: 10.3233/Jad-170298 |
0.335 |
|
| 2017 |
Lacampagne A, Liu X, Reiken S, Bussiere R, Meli AC, Lauritzen I, Teich AF, Zalk R, Saint N, Arancio O, Bauer C, Duprat F, Briggs CA, Chakroborty S, Stutzmann GE, et al. Post-translational remodeling of ryanodine receptor induces calcium leak leading to Alzheimer's disease-like pathologies and cognitive deficits. Acta Neuropathologica. PMID 28631094 DOI: 10.1007/S00401-017-1733-7 |
0.44 |
|
| 2017 |
Palmeri A, Ricciarelli R, Gulisano W, Rivera D, Rebosio C, Calcagno E, Rosaria Tropea M, Conti S, Das U, Roy S, Pronzato MA, Arancio O, Fedele E, Puzzo D. Amyloid-beta peptide is needed for cGMP-induced long-term potentiation and memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28626017 DOI: 10.1523/Jneurosci.3607-16.2017 |
0.488 |
|
| 2017 |
Piacentini R, Li Puma DD, Mainardi M, Lazzarino G, Tavazzi B, Arancio O, Grassi C. Reduced Gliotransmitter Release from Astrocytes Mediates Tau-Induced Synaptic Dysfunction in Cultured Hippocampal Neurons. Glia. PMID 28519902 DOI: 10.1002/Glia.23163 |
0.471 |
|
| 2017 |
Ricciarelli R, Brullo C, Prickaerts J, Arancio O, Villa C, Rebosio C, Calcagno E, Balbi M, van Hagen BT, Argyrousi EK, Zhang H, Pronzato MA, Bruno O, Fedele E. Memory-enhancing effects of GEBR-32a, a new PDE4D inhibitor holding promise for the treatment of Alzheimer's disease. Scientific Reports. 7: 46320. PMID 28402318 DOI: 10.1038/Srep46320 |
0.394 |
|
| 2017 |
Puzzo D, Piacentini R, Fá M, Gulisano W, Puma DDL, Staniszewski A, Zhang H, Tropea MR, Cocco S, Palmeri A, Fraser P, D'Adamio L, Grassi C, Arancio O. Author response: LTP and memory impairment caused by extracellular Aβ and Tau oligomers is APP-dependent Elife. DOI: 10.7554/Elife.26991.025 |
0.436 |
|
| 2017 |
Van Eldik LJ, Roy SM, Arancio O, Watterson DM. A PLATFORM FOR NOVEL IN VIVO MOLECULAR PROBES FOR ATTENUATION OF SYNAPTIC DYSFUNCTION AND PROINFLAMMATORY CYTOKINE OVERPRODUCTION Alzheimer's & Dementia. 13: P951-P952. DOI: 10.1016/J.Jalz.2017.06.1265 |
0.373 |
|
| 2016 |
Koppensteiner P, Trinchese F, Fà M, Puzzo D, Gulisano W, Yan S, Poussin A, Liu S, Orozco I, Dale E, Teich AF, Palmeri A, Ninan I, Boehm S, Arancio O. Time-dependent reversal of synaptic plasticity induced by physiological concentrations of oligomeric Aβ42: an early index of Alzheimer's disease. Scientific Reports. 6: 32553. PMID 27581852 DOI: 10.1038/Srep32553 |
0.794 |
|
| 2016 |
Brullo C, Ricciarelli R, Prickaerts J, Arancio O, Massa M, Rotolo C, Romussi A, Rebosio C, Marengo B, Pronzato MA, van Hagen BT, van Goethem NP, D'Ursi P, Orro A, Milanesi L, et al. New insights into selective PDE4D inhibitors: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde O-(2-(2,6-dimethylmorpholino)-2-oxoethyl) oxime (GEBR-7b) structural development and promising activities to restore memory impairment. European Journal of Medicinal Chemistry. 124: 82-102. PMID 27560284 DOI: 10.1016/J.Ejmech.2016.08.018 |
0.411 |
|
| 2016 |
Manassero G, Guglielmotto M, Zamfir R, Borghi R, Colombo L, Salmona M, Perry G, Odetti P, Arancio O, Tamagno E, Tabaton M. Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein. Aging Cell. PMID 27406053 DOI: 10.1111/Acel.12500 |
0.429 |
|
| 2016 |
Luo J, Lee SH, VandeVrede L, Qin Z, Aissa MB, Larson J, Teich AF, Arancio O, D'Souza Y, Elharram A, Koster K, Tai LM, LaDu MJ, Bennett BM, Thatcher GR. Erratum to: A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease. Molecular Neurodegeneration. 11: 40. PMID 27194246 DOI: 10.1186/S13024-016-0104-5 |
0.311 |
|
| 2016 |
Luo J, Lee SH, VandeVrede L, Qin Z, Ben Aissa M, Larson J, Teich AF, Arancio O, D'Souza Y, Elharram A, Koster K, Tai LM, LaDu MJ, Bennett BM, Thatcher GR. A multifunctional therapeutic approach to disease modification in multiple familial mouse models and a novel sporadic model of Alzheimer's disease. Molecular Neurodegeneration. 11: 35. PMID 27129593 DOI: 10.1186/S13024-016-0103-6 |
0.419 |
|
| 2016 |
Teich AF, Sakurai M, Patel M, Holman C, Saeed F, Fiorito J, Arancio O. PDE5 Exists in Human Neurons and is a Viable Therapeutic Target for Neurologic Disease. Journal of Alzheimer's Disease : Jad. PMID 26967220 DOI: 10.3233/Jad-151104 |
0.313 |
|
| 2016 |
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951658 DOI: 10.1073/Pnas.1521018113 |
0.57 |
|
| 2016 |
Fá M, Puzzo D, Piacentini R, Staniszewski A, Zhang H, Baltrons MA, Li Puma DD, Chatterjee I, Li J, Saeed F, Berman HL, Ripoli C, Gulisano W, Gonzalez J, Tian H, ... ... Arancio O, et al. Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory. Scientific Reports. 6: 19393. PMID 26786552 DOI: 10.1038/Srep19393 |
0.456 |
|
| 2016 |
Ben Aissa M, Lee SH, Luo J, Arancio O, LaDu MJ, Bennett BM, Pepperberg DR, Thatcher GR. P1-035: NO/CGMP/CREB-Based Synaptic Repair as a Multifunctional Therapeutic Approach to Disease Modification in Multiple Familial Mouse Models and a Novel Sporadic Model Of Alzheimer's Disease Alzheimer's & Dementia. 12: P414-P414. DOI: 10.1016/J.Jalz.2016.06.782 |
0.391 |
|
| 2015 |
Fà M, Zhang H, Staniszewski A, Saeed F, Shen LW, Schiefer IT, Siklos MI, Tapadar S, Litosh VA, Libien J, Petukhov PA, Teich AF, Thatcher GR, Arancio O. Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26484927 DOI: 10.3233/Jad-150618 |
0.408 |
|
| 2015 |
Luo J, Lee SH, VandeVrede L, Qin Z, Piyankarage S, Tavassoli E, Asghodom RT, Aissa MB, Fà M, Arancio O, Yue L, Pepperberg DR, Thatcher GR. Re-engineering a neuroprotective, clinical drug as a procognitive agent with high in vivo potency and with GABAA potentiating activity for use in dementia. Bmc Neuroscience. 16: 67. PMID 26480871 DOI: 10.1186/S12868-015-0208-9 |
0.48 |
|
| 2015 |
Puzzo D, Gulisano W, Arancio O, Palmeri A. The keystone of Alzheimer pathogenesis might be sought in Aβ physiology. Neuroscience. 307: 26-36. PMID 26314631 DOI: 10.1016/J.Neuroscience.2015.08.039 |
0.503 |
|
| 2015 |
Lee L, Dale E, Staniszewski A, Zhang H, Saeed F, Sakurai M, Fa' M, Orozco I, Michelassi F, Akpan N, Lehrer H, Arancio O. Corrigendum: Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease. Scientific Reports. 5: 11782. PMID 26149080 DOI: 10.1038/Srep11782 |
0.783 |
|
| 2015 |
Fang D, Wang Y, Zhang Z, Du H, Yan S, Sun Q, Zhong C, Wu L, Vangavaragu JR, Yan S, Hu G, Guo L, Rabinowitz M, Glaser E, Arancio O, et al. Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation, and improves mitochondrial and synaptic function in Alzheimer disease's mouse model. Human Molecular Genetics. PMID 26123488 DOI: 10.1093/Hmg/Ddv241 |
0.473 |
|
| 2015 |
Chinchalongporn V, Koppensteiner P, Prè D, Thangnipon W, Bilo L, Arancio O. Connectivity and circuitry in a dish versus in a brain. Alzheimer's Research & Therapy. 7: 44. PMID 26045718 DOI: 10.1186/S13195-015-0129-Y |
0.339 |
|
| 2015 |
Matsuzaki S, Lee L, Knock E, Srikumar T, Sakurai M, Hazrati LN, Katayama T, Staniszewski A, Raught B, Arancio O, Fraser PE. SUMO1 Affects Synaptic Function, Spine Density and Memory. Scientific Reports. 5: 10730. PMID 26022678 DOI: 10.1038/Srep10730 |
0.609 |
|
| 2015 |
Puzzo D, Gulisano W, Palmeri A, Arancio O. Rodent models for Alzheimer's disease drug discovery. Expert Opinion On Drug Discovery. 10: 703-11. PMID 25927677 DOI: 10.1517/17460441.2015.1041913 |
0.416 |
|
| 2015 |
Kim S, Titcombe RF, Zhang H, Khatri L, Girma HK, Hofmann F, Arancio O, Ziff EB. Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca2+-permeable AMPA receptors. Proceedings of the National Academy of Sciences of the United States of America. 112: 3122-7. PMID 25713349 DOI: 10.1073/Pnas.1417498112 |
0.417 |
|
| 2015 |
Roy SM, Grum-Tokars VL, Schavocky JP, Saeed F, Staniszewski A, Teich AF, Arancio O, Bachstetter AD, Webster SJ, Van Eldik LJ, Minasov G, Anderson WF, Pelletier JC, Watterson DM. Targeting human central nervous system protein kinases: An isoform selective p38αMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models. Acs Chemical Neuroscience. 6: 666-80. PMID 25676389 DOI: 10.1021/Acschemneuro.5B00002 |
0.358 |
|
| 2015 |
Teich AF, Nicholls RE, Puzzo D, Fiorito J, Purgatorio R, Fa' M, Arancio O. Synaptic therapy in Alzheimer's disease: a CREB-centric approach. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 12: 29-41. PMID 25575647 DOI: 10.1007/S13311-014-0327-5 |
0.486 |
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| 2015 |
Van Eldik LJ, Roy SM, Watterson DM, Arancio O. P1-304: An optimized and isoform-selective p38aMAPK inhibitor that attenuates disease progression in Alzheimer's disease mouse models Alzheimer's & Dementia. 11: P473-P473. DOI: 10.1016/J.Jalz.2015.06.519 |
0.324 |
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| 2014 |
Lee L, Dale E, Staniszewski A, Zhang H, Saeed F, Sakurai M, Fa' M, Orozco I, Michelassi F, Akpan N, Lehrer H, Arancio O. Regulation of synaptic plasticity and cognition by SUMO in normal physiology and Alzheimer's disease. Scientific Reports. 4: 7190. PMID 25448527 DOI: 10.1038/Srep07190 |
0.814 |
|
| 2014 |
Koppensteiner P, Boehm S, Arancio O. Electrophysiological profiles of induced neurons converted directly from adult human fibroblasts indicate incomplete neuronal conversion. Cellular Reprogramming. 16: 439-46. PMID 25437871 DOI: 10.1089/Cell.2014.0054 |
0.301 |
|
| 2014 |
Izzo NJ, Xu J, Zeng C, Kirk MJ, Mozzoni K, Silky C, Rehak C, Yurko R, Look G, Rishton G, Safferstein H, Cruchaga C, Goate A, Cahill MA, Arancio O, et al. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity. Plos One. 9: e111899. PMID 25390692 DOI: 10.1371/Journal.Pone.0111899 |
0.491 |
|
| 2014 |
Izzo NJ, Staniszewski A, To L, Fa M, Teich AF, Saeed F, Wostein H, Walko T, Vaswani A, Wardius M, Syed Z, Ravenscroft J, Mozzoni K, Silky C, Rehak C, ... ... Arancio O, et al. Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers I: Abeta 42 oligomer binding to specific neuronal receptors is displaced by drug candidates that improve cognitive deficits. Plos One. 9: e111898. PMID 25390368 DOI: 10.1371/Journal.Pone.0111898 |
0.473 |
|
| 2014 |
Yan S, Li Z, Li H, Arancio O, Zhang W. Notoginsenoside R1 increases neuronal excitability and ameliorates synaptic and memory dysfunction following amyloid elevation. Scientific Reports. 4: 6352. PMID 25213453 DOI: 10.1038/Srep06352 |
0.514 |
|
| 2014 |
Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, et al. Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits. Neuron. 83: 1131-43. PMID 25155956 DOI: 10.1016/J.Neuron.2014.07.040 |
0.395 |
|
| 2014 |
Guglielmotto M, Monteleone D, Piras A, Valsecchi V, Tropiano M, Ariano S, Fornaro M, Vercelli A, Puyal J, Arancio O, Tabaton M, Tamagno E. Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis. Autophagy. 10: 1827-43. PMID 25136804 DOI: 10.4161/Auto.30001 |
0.366 |
|
| 2014 |
Prè D, Nestor MW, Sproul AA, Jacob S, Koppensteiner P, Chinchalongporn V, Zimmer M, Yamamoto A, Noggle SA, Arancio O. A time course analysis of the electrophysiological properties of neurons differentiated from human induced pluripotent stem cells (iPSCs). Plos One. 9: e103418. PMID 25072157 DOI: 10.1371/Journal.Pone.0103418 |
0.331 |
|
| 2014 |
Origlia N, Criscuolo C, Arancio O, Yan SS, Domenici L. RAGE inhibition in microglia prevents ischemia-dependent synaptic dysfunction in an amyloid-enriched environment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8749-60. PMID 24966375 DOI: 10.1523/Jneurosci.0141-14.2014 |
0.511 |
|
| 2014 |
FÃ M, Staniszewski A, Saeed F, Francis YI, Arancio O. Dynamin 1 is required for memory formation. Plos One. 9: e91954. PMID 24643165 DOI: 10.1371/Journal.Pone.0091954 |
0.423 |
|
| 2014 |
Ricciarelli R, Puzzo D, Bruno O, Canepa E, Gardella E, Rivera D, Privitera L, Domenicotti C, Marengo B, Marinari UM, Palmeri A, Pronzato MA, Arancio O, Fedele E. A novel mechanism for cyclic adenosine monophosphate-mediated memory formation: Role of amyloid beta. Annals of Neurology. 75: 602-7. PMID 24591104 DOI: 10.1002/Ana.24130 |
0.461 |
|
| 2014 |
Puzzo D, Lee L, Palmeri A, Calabrese G, Arancio O. Behavioral assays with mouse models of Alzheimer's disease: practical considerations and guidelines. Biochemical Pharmacology. 88: 450-67. PMID 24462904 DOI: 10.1016/J.Bcp.2014.01.011 |
0.576 |
|
| 2014 |
Sproul AA, Jacob S, Pre D, Kim SH, Nestor MW, Navarro-Sobrino M, Santa-Maria I, Zimmer M, Aubry S, Steele JW, Kahler DJ, Dranovsky A, Arancio O, Crary JF, Gandy S, et al. Characterization and molecular profiling of PSEN1 familial Alzheimer's disease iPSC-derived neural progenitors. Plos One. 9: e84547. PMID 24416243 DOI: 10.1371/Journal.Pone.0084547 |
0.335 |
|
| 2014 |
Orozco IJ, Koppensteiner P, Ninan I, Arancio O. The schizophrenia susceptibility gene DTNBP1 modulates AMPAR synaptic transmission and plasticity in the hippocampus of juvenile DBA/2J mice. Molecular and Cellular Neurosciences. 58: 76-84. PMID 24321452 DOI: 10.1016/J.Mcn.2013.12.003 |
0.76 |
|
| 2014 |
Puzzo D, Loreto C, Giunta S, Musumeci G, Frasca G, Podda MV, Arancio O, Palmeri A. Effect of phosphodiesterase-5 inhibition on apoptosis and beta amyloid load in aged mice. Neurobiology of Aging. 35: 520-31. PMID 24112792 DOI: 10.1016/J.Neurobiolaging.2013.09.002 |
0.437 |
|
| 2014 |
Lee L, Kosuri P, Arancio O. Picomolar amyloid-β peptides enhance spontaneous astrocyte calcium transients. Journal of Alzheimer's Disease : Jad. 38: 49-62. PMID 23948929 DOI: 10.3233/Jad-130740 |
0.59 |
|
| 2014 |
Tang G, Gudsnuk K, Kuo SH, Cotrina ML, Rosoklija G, Sosunov A, Sonders MS, Kanter E, Castagna C, Yamamoto A, Yue Z, Arancio O, Peterson BS, Champagne F, Dwork AJ, et al. Erratam to Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits[Neuron, 83, (2014), 1131-1143] Neuron. 83: 1482. DOI: 10.1016/j.neuron.2014.09.001 |
0.318 |
|
| 2014 |
Fedele E, Puzzo D, Bruno O, Canepa E, Gardella E, Rivera D, Privitera L, Domenicotti C, Marengo B, Marinari U, Palmeri A, Pronzato M, Arancio O, Ricciarelli R. A Physiological Role For Amyloid Beta In Cyclic Amp-Stimulated Long Term Potentiation Alzheimers & Dementia. 10: 328. DOI: 10.1016/J.Jalz.2014.05.304 |
0.333 |
|
| 2013 |
Lee L, Sakurai M, Matsuzaki S, Arancio O, Fraser P. SUMO and Alzheimer's disease. Neuromolecular Medicine. 15: 720-36. PMID 23979993 DOI: 10.1007/S12017-013-8257-7 |
0.6 |
|
| 2013 |
Watterson DM, Grum-Tokars VL, Roy SM, Schavocky JP, Bradaric BD, Bachstetter AD, Xing B, Dimayuga E, Saeed F, Zhang H, Staniszewski A, Pelletier JC, Minasov G, Anderson WF, Arancio O, et al. Development of Novel In Vivo Chemical Probes to Address CNS Protein Kinase Involvement in Synaptic Dysfunction. Plos One. 8: e66226. PMID 23840427 DOI: 10.1371/Journal.Pone.0066226 |
0.391 |
|
| 2013 |
Schiefer IT, Tapadar S, Litosh V, Siklos M, Scism R, Wijewickrama GT, Chandrasena EP, Sinha V, Tavassoli E, Brunsteiner M, Fa' M, Arancio O, Petukhov P, Thatcher GR. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. Journal of Medicinal Chemistry. 56: 6054-68. PMID 23834438 DOI: 10.1021/Jm4006719 |
0.304 |
|
| 2013 |
Pozueta J, Lefort R, Ribe EM, Troy CM, Arancio O, Shelanski M. Caspase-2 is required for dendritic spine and behavioural alterations in J20 APP transgenic mice. Nature Communications. 4: 1939. PMID 23748737 DOI: 10.1038/Ncomms2927 |
0.442 |
|
| 2013 |
Knowles JK, Simmons DA, Nguyen TV, Vander Griend L, Xie Y, Zhang H, Yang T, Pollak J, Chang T, Arancio O, Buckwalter MS, Wyss-Coray T, Massa SM, Longo FM. Small molecule p75NTR ligand prevents cognitive deficits and neurite degeneration in an Alzheimer's mouse model. Neurobiology of Aging. 34: 2052-63. PMID 23545424 DOI: 10.1016/J.Neurobiolaging.2013.02.015 |
0.427 |
|
| 2013 |
Lombino F, Biundo F, Tamayev R, Arancio O, D'Adamio L. An intracellular threonine of amyloid-β precursor protein mediates synaptic plasticity deficits and memory loss. Plos One. 8: e57120. PMID 23451158 DOI: 10.1371/Journal.Pone.0057120 |
0.491 |
|
| 2013 |
Teich AF, Patel M, Arancio O. A reliable way to detect endogenous murine β-amyloid. Plos One. 8: e55647. PMID 23383341 DOI: 10.1371/Journal.Pone.0055647 |
0.35 |
|
| 2013 |
Fiorito J, Saeed F, Zhang H, Staniszewski A, Feng Y, Francis YI, Rao S, Thakkar DM, Deng SX, Landry DW, Arancio O. Synthesis of quinoline derivatives: discovery of a potent and selective phosphodiesterase 5 inhibitor for the treatment of Alzheimer's disease. European Journal of Medicinal Chemistry. 60: 285-94. PMID 23313637 DOI: 10.1016/J.Ejmech.2012.12.009 |
0.411 |
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| 2013 |
Xing L, Salas M, Zhang H, Gittler J, Ludwig T, Lin CS, Murty VV, Silverman W, Arancio O, Tycko B. Creation and characterization of BAC-transgenic mice with physiological overexpression of epitope-tagged RCAN1 (DSCR1). Mammalian Genome : Official Journal of the International Mammalian Genome Society. 24: 30-43. PMID 23096997 DOI: 10.1007/S00335-012-9436-9 |
0.35 |
|
| 2013 |
Puzzo D, Arancio O. Amyloid-β peptide: Dr. Jekyll or Mr. Hyde? Journal of Alzheimer's Disease : Jad. 33: S111-20. PMID 22735675 DOI: 10.3233/Jad-2012-129033 |
0.503 |
|
| 2013 |
Watterson DM, Pelletier J, Anderson W, Arancio O, Van Eldik L. P4-313: Revisiting protein kinases as CNS targets: Attenuation of synaptic dysfunction Alzheimer's & Dementia. 9: P818-P819. DOI: 10.1016/J.Jalz.2013.05.1758 |
0.37 |
|
| 2013 |
Longo F, Nguyen T, Simmons D, Yang T, Knowles J, Zhang H, Arancio O, Massa S, Longo F. S4-02-04: Targeting Alzheimer's disease-related mechanisms with p75 ligands Alzheimer's & Dementia. 9: P674-P674. DOI: 10.1016/J.Jalz.2013.04.323 |
0.302 |
|
| 2013 |
Ren H, Orozco I, Su Y, Suyama S, Gutiérrez-Juárez R, Horvath T, Wardlaw S, Plum L, Arancio O, Accili D. FoxO1 Target Gpr17 Activates AgRP Neurons to Regulate Food Intake Cell. 153: 1166. DOI: 10.1016/J.Cell.2013.05.010 |
0.703 |
|
| 2012 |
Tamayev R, Akpan N, Arancio O, Troy CM, D'Adamio L. Caspase-9 mediates synaptic plasticity and memory deficits of Danish dementia knock-in mice: caspase-9 inhibition provides therapeutic protection. Molecular Neurodegeneration. 7: 60. PMID 23217200 DOI: 10.1186/1750-1326-7-60 |
0.447 |
|
| 2012 |
McIntire LB, Berman DE, Myaeng J, Staniszewski A, Arancio O, Di Paolo G, Kim TW. Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15271-6. PMID 23115165 DOI: 10.1523/Jneurosci.2034-12.2012 |
0.533 |
|
| 2012 |
Liu X, Betzenhauser MJ, Reiken S, Meli AC, Xie W, Chen BX, Arancio O, Marks AR. Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction. Cell. 150: 1055-67. PMID 22939628 DOI: 10.1016/J.Cell.2012.06.052 |
0.367 |
|
| 2012 |
Teich AF, Arancio O. Is the amyloid hypothesis of Alzheimer's disease therapeutically relevant? The Biochemical Journal. 446: 165-77. PMID 22891628 DOI: 10.1042/Bj20120653 |
0.399 |
|
| 2012 |
Hashimoto G, Sakurai M, Teich AF, Saeed F, Aziz F, Arancio O. 5-HT₄ receptor stimulation leads to soluble AβPPα production through MMP-9 upregulation. Journal of Alzheimer's Disease : Jad. 32: 437-45. PMID 22810092 DOI: 10.3233/Jad-2012-111235 |
0.31 |
|
| 2012 |
Qin Z, Luo J, VandeVrede L, Tavassoli E, Fa' M, Teich AF, Arancio O, Thatcher GR. Design and synthesis of neuroprotective methylthiazoles and modification as NO-chimeras for neurodegenerative therapy. Journal of Medicinal Chemistry. 55: 6784-801. PMID 22779770 DOI: 10.1021/Jm300353R |
0.498 |
|
| 2012 |
Ren H, Orozco IJ, Su Y, Suyama S, Gutiérrez-Juárez R, Horvath TL, Wardlaw SL, Plum L, Arancio O, Accili D. FoxO1 target Gpr17 activates AgRP neurons to regulate food intake. Cell. 149: 1314-26. PMID 22682251 DOI: 10.1016/j.cell.2012.04.032 |
0.705 |
|
| 2012 |
Gaisler-Salomon I, Wang Y, Chuhma N, Zhang H, Golumbic YN, Mihali A, Arancio O, Sibille E, Rayport S. Synaptic underpinnings of altered hippocampal function in glutaminase-deficient mice during maturation. Hippocampus. 22: 1027-39. PMID 22431402 DOI: 10.1002/Hipo.22014 |
0.388 |
|
| 2012 |
Schiefer IT, VandeVrede L, Fa' M, Arancio O, Thatcher GR. Furoxans (1,2,5-oxadiazole-N-oxides) as novel NO mimetic neuroprotective and procognitive agents. Journal of Medicinal Chemistry. 55: 3076-87. PMID 22429006 DOI: 10.1021/Jm201504S |
0.409 |
|
| 2012 |
Tamayev R, Matsuda S, Arancio O, D'Adamio L. β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia. Embo Molecular Medicine. 4: 171-9. PMID 22170863 DOI: 10.1002/Emmm.201100195 |
0.441 |
|
| 2012 |
Origlia N, Criscuolo C, Arancio O, ShiDu Yan S, Domenici L. P4-037: Ischemia as a trigger for RAGE-dependent synaptic dysfunction in an amyloid-enriched environment Alzheimer's & Dementia. 8: P649-P649. DOI: 10.1016/J.Jalz.2012.05.1738 |
0.448 |
|
| 2011 |
Tamayev R, Matsuda S, Giliberto L, Arancio O, D'Adamio L. APP heterozygosity averts memory deficit in knockin mice expressing the Danish dementia BRI2 mutant. The Embo Journal. 30: 2501-9. PMID 21587206 DOI: 10.1038/Emboj.2011.161 |
0.476 |
|
| 2011 |
Puzzo D, Privitera L, Fa' M, Staniszewski A, Hashimoto G, Aziz F, Sakurai M, Ribe EM, Troy CM, Mercken M, Jung SS, Palmeri A, Arancio O. Endogenous amyloid-β is necessary for hippocampal synaptic plasticity and memory. Annals of Neurology. 69: 819-30. PMID 21472769 DOI: 10.1002/Ana.22313 |
0.435 |
|
| 2011 |
Duffy AM, Schaner MJ, Wu SH, Staniszewski A, Kumar A, Arévalo JC, Arancio O, Chao MV, Scharfman HE. A selective role for ARMS/Kidins220 scaffold protein in spatial memory and trophic support of entorhinal and frontal cortical neurons. Experimental Neurology. 229: 409-20. PMID 21419124 DOI: 10.1016/J.Expneurol.2011.03.008 |
0.328 |
|
| 2011 |
Yao J, Du H, Yan S, Fang F, Wang C, Lue LF, Guo L, Chen D, Stern DM, Gunn Moore FJ, Xi Chen J, Arancio O, Yan SS. Inhibition of amyloid-beta (Abeta) peptide-binding alcohol dehydrogenase-Abeta interaction reduces Abeta accumulation and improves mitochondrial function in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 2313-20. PMID 21307267 DOI: 10.1523/Jneurosci.4717-10.2011 |
0.411 |
|
| 2011 |
Puzzo D, Arancio O, Privitera L, Palmeri A, Furnari D. P1-014: Hormetic effect of amyloid-beta peptide on synaptic plasticity and memory Alzheimer's & Dementia. 7: S116-S116. DOI: 10.1016/J.Jalz.2011.05.293 |
0.429 |
|
| 2011 |
Fa M, Koppensteiner P, Trinchese F, Liu S, Ninan I, Arancio O. P3-219: Picomolar Beta-Amyloid progressively impairs synaptic plasticity over time while simultaneously increases spontaneous neurotransmission Alzheimer's & Dementia. 7: S586-S586. DOI: 10.1016/J.Jalz.2011.05.1660 |
0.449 |
|
| 2011 |
Origlia N, Arancio O, Du Yan S, Domenici L. P2-255: Microglial RAGE-dependent signal pathway contributes to synaptic dysfunction induced by amyloid and transient ischemia in entorhinal cortex Alzheimer's & Dementia. 7: S393-S393. DOI: 10.1016/J.Jalz.2011.05.1136 |
0.408 |
|
| 2010 |
Oliveira TG, Chan RB, Tian H, Laredo M, Shui G, Staniszewski A, Zhang H, Wang L, Kim TW, Duff KE, Wenk MR, Arancio O, Di Paolo G. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16419-28. PMID 21147981 DOI: 10.1523/Jneurosci.3317-10.2010 |
0.458 |
|
| 2010 |
Tamayev R, Matsuda S, FÃ M, Arancio O, D'Adamio L. Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits. Proceedings of the National Academy of Sciences of the United States of America. 107: 20822-7. PMID 21098268 DOI: 10.1073/Pnas.1011689107 |
0.454 |
|
| 2010 |
Tamayev R, Giliberto L, Li W, d'Abramo C, Arancio O, Vidal R, D'Adamio L. Memory deficits due to familial British dementia BRI2 mutation are caused by loss of BRI2 function rather than amyloidosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 14915-24. PMID 21048150 DOI: 10.1523/Jneurosci.3917-10.2010 |
0.352 |
|
| 2010 |
Wu SH, Arévalo JC, Neubrand VE, Zhang H, Arancio O, Chao MV. The ankyrin repeat-rich membrane spanning (ARMS)/Kidins220 scaffold protein is regulated by activity-dependent calpain proteolysis and modulates synaptic plasticity. The Journal of Biological Chemistry. 285: 40472-8. PMID 20943655 DOI: 10.1074/Jbc.M110.171371 |
0.462 |
|
| 2010 |
Origlia N, Bonadonna C, Rosellini A, Leznik E, Arancio O, Yan SS, Domenici L. Microglial receptor for advanced glycation end product-dependent signal pathway drives beta-amyloid-induced synaptic depression and long-term depression impairment in entorhinal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11414-25. PMID 20739563 DOI: 10.1523/Jneurosci.2127-10.2010 |
0.474 |
|
| 2010 |
Fa M, Orozco IJ, Francis YI, Saeed F, Gong Y, Arancio O. Preparation of oligomeric beta-amyloid 1-42 and induction of synaptic plasticity impairment on hippocampal slices. Journal of Visualized Experiments : Jove. PMID 20644518 DOI: 10.3791/1884 |
0.769 |
|
| 2010 |
Arévalo JC, Wu SH, Takahashi T, Zhang H, Yu T, Yano H, Milner TA, Tessarollo L, Ninan I, Arancio O, Chao MV. The ARMS/Kidins220 scaffold protein modulates synaptic transmission. Molecular and Cellular Neurosciences. 45: 92-100. PMID 20547223 DOI: 10.1016/J.Mcn.2010.06.002 |
0.428 |
|
| 2010 |
Lee L, Dale E, Staniszewski A, Zhang H, Michelassi F, Sakurai M, Kapadia C, Arancio O. P4-030: Elevated Amyloid-beta Impairs Protein Sumoylation Alzheimer's & Dementia. 6: e29-e29. DOI: 10.1016/J.Jalz.2010.08.090 |
0.531 |
|
| 2010 |
McIntire LBJ, Berman D, Myaeng J, Staniszewski A, Arancio O, Paolo GD, Kim T. Hemizygous deletion of synaptojanin1 ameliorates learning and memory impairments in a mouse model of Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.024 |
0.367 |
|
| 2010 |
Moe JG, Chatterjee I, Puzzo D, Agnieszka S, Fa M, Davidowitz EJ, Arancio O. P1-361: Extracellular oligomeric tau inhibits memory formation in mice Alzheimer's & Dementia. 6: S277-S277. DOI: 10.1016/J.Jalz.2010.05.915 |
0.338 |
|
| 2010 |
Oliveira TG, Chan RB, Tian H, Staniszewski A, Zhang H, Wang L, Kim T, Duff KE, Wenk MR, Arancio O, Paolo GD. Phospholipase D2 ablation ameliorates Alzheimer-linked synaptic dysfunction and cognitive deficits: Mechanistic insights from lipidomic analysis Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.1389 |
0.409 |
|
| 2010 |
Fa M, Leznik E, Ninan I, Trinchese F, Liu S, Orozco IJ, Koppensteiner P, Arancio O. P2-333: Enhanced spontaneous release of neurotransmitter underlies early changes in synaptic function by beta-amyloid Alzheimer's & Dementia. 6: S411-S411. DOI: 10.1016/J.Jalz.2010.05.1384 |
0.756 |
|
| 2009 |
Origlia N, Arancio O, Domenici L, Yan SS. MAPK, beta-amyloid and synaptic dysfunction: the role of RAGE. Expert Review of Neurotherapeutics. 9: 1635-45. PMID 19903023 DOI: 10.1586/Ern.09.107 |
0.493 |
|
| 2009 |
Smith DL, Pozueta J, Gong B, Arancio O, Shelanski M. Reversal of long-term dendritic spine alterations in Alzheimer disease models. Proceedings of the National Academy of Sciences of the United States of America. 106: 16877-82. PMID 19805389 DOI: 10.1073/Pnas.0908706106 |
0.469 |
|
| 2009 |
Francis YI, FÃ M, Ashraf H, Zhang H, Staniszewski A, Latchman DS, Arancio O. Dysregulation of histone acetylation in the APP/PS1 mouse model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 18: 131-9. PMID 19625751 DOI: 10.3233/Jad-2009-1134 |
0.401 |
|
| 2009 |
Puzzo D, Staniszewski A, Deng SX, Privitera L, Leznik E, Liu S, Zhang H, Feng Y, Palmeri A, Landry DW, Arancio O. Phosphodiesterase 5 inhibition improves synaptic function, memory, and amyloid-beta load in an Alzheimer's disease mouse model. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8075-86. PMID 19553447 DOI: 10.1523/Jneurosci.0864-09.2009 |
0.484 |
|
| 2009 |
Gaisler-Salomon I, Miller GM, Chuhma N, Lee S, Zhang H, Ghoddoussi F, Lewandowski N, Fairhurst S, Wang Y, Conjard-Duplany A, Masson J, Balsam P, Hen R, Arancio O, Galloway MP, et al. Glutaminase-deficient mice display hippocampal hypoactivity, insensitivity to pro-psychotic drugs and potentiated latent inhibition: relevance to schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 34: 2305-22. PMID 19516252 DOI: 10.1038/Npp.2009.58 |
0.36 |
|
| 2009 |
Basavarajappa BS, Nixon RA, Arancio O. Endocannabinoid system: emerging role from neurodevelopment to neurodegeneration. Mini Reviews in Medicinal Chemistry. 9: 448-62. PMID 19356123 DOI: 10.2174/138955709787847921 |
0.322 |
|
| 2009 |
Origlia N, Capsoni S, Cattaneo A, Fang F, Arancio O, Yan SD, Domenici L. Abeta-dependent Inhibition of LTP in different intracortical circuits of the visual cortex: the role of RAGE. Journal of Alzheimer's Disease : Jad. 17: 59-68. PMID 19221410 DOI: 10.3233/Jad-2009-1045 |
0.414 |
|
| 2009 |
Vitolo O, Gong B, Cao Z, Ishii H, Jaracz S, Nakanishi K, Arancio O, Dzyuba SV, Lefort R, Shelanski M. Protection against beta-amyloid induced abnormal synaptic function and cell death by Ginkgolide J. Neurobiology of Aging. 30: 257-65. PMID 17640772 DOI: 10.1016/J.Neurobiolaging.2007.05.025 |
0.409 |
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| 2009 |
Arancio O. Amyloid-beta: From physiology to pathology Neuroscience Research. 65: S4. DOI: 10.1016/J.Neures.2009.09.1484 |
0.326 |
|
| 2009 |
Puzzo D, Privitera L, Leznik E, Fa’ M, Staniszewsky A, Hashimoto G, Aziz F, Sakurai M, Ribe EM, Mathews PM, Troy CM, Mercken M, Jung SS, Palmeri A, Arancio O. O4-03-05: Amyloid-beta peptide is required for synaptic plasticity and memory Alzheimer's & Dementia. 5: P155-P155. DOI: 10.1016/J.Jalz.2009.05.535 |
0.412 |
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| 2009 |
Moe JG, Chatterjee I, Davidowitz EJ, Arancio O. P4-236: Modulation of synaptic function by extracellular tau enriched in oligomers Alzheimer's & Dementia. 5: P499-P499. DOI: 10.1016/J.Jalz.2009.04.702 |
0.416 |
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| 2009 |
Domenici L, Origlia N, Capsoni S, Cattaneo A, Fang F, Arancio O, Yan SD. P4-234: Aβ-dependent inhibition of LTP in different intra-cortical circuits of the visual cortex is mediated by RAGE Alzheimer's & Dementia. 5: P499-P499. DOI: 10.1016/J.Jalz.2009.04.700 |
0.312 |
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| 2009 |
Origlia N, Arancio O, Yan SD, Domenici L. P4-231: Neuronal and microglial RAGE-dependent signal pathways involved in Aβ-induced synaptic dysfunction in entorhinal cortex Alzheimer's & Dementia. 5: P498-P498. DOI: 10.1016/J.Jalz.2009.04.697 |
0.437 |
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| 2009 |
Bonadonna C, Origlia N, Rosellini A, Arancio O, Yan S, Domenici L. P4-221: BDNF prevents activation of stress related kinases by Aβ in cortical neurons Alzheimer's & Dementia. 5: P495-P495. DOI: 10.1016/J.Jalz.2009.04.687 |
0.339 |
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| 2008 |
Puzzo D, Privitera L, Leznik E, FÃ M, Staniszewski A, Palmeri A, Arancio O. Picomolar amyloid-beta positively modulates synaptic plasticity and memory in hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 14537-45. PMID 19118188 DOI: 10.1523/Jneurosci.2692-08.2008 |
0.476 |
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| 2008 |
Yang T, Knowles JK, Lu Q, Zhang H, Arancio O, Moore LA, Chang T, Wang Q, Andreasson K, Rajadas J, Fuller GG, Xie Y, Massa SM, Longo FM. Small molecule, non-peptide p75 ligands inhibit Abeta-induced neurodegeneration and synaptic impairment. Plos One. 3: e3604. PMID 18978948 DOI: 10.1371/Journal.Pone.0003604 |
0.449 |
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| 2008 |
Du H, Guo L, Fang F, Chen D, Sosunov AA, McKhann GM, Yan Y, Wang C, Zhang H, Molkentin JD, Gunn-Moore FJ, Vonsattel JP, Arancio O, Chen JX, Yan SD. Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease. Nature Medicine. 14: 1097-105. PMID 18806802 DOI: 10.1038/Nm.1868 |
0.432 |
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| 2008 |
Basavarajappa BS, Ninan I, Arancio O. Acute ethanol suppresses glutamatergic neurotransmission through endocannabinoids in hippocampal neurons. Journal of Neurochemistry. 107: 1001-13. PMID 18796007 DOI: 10.1111/J.1471-4159.2008.05685.X |
0.316 |
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| 2008 |
Puzzo D, Sapienza S, Arancio O, Palmeri A. Role of phosphodiesterase 5 in synaptic plasticity and memory. Neuropsychiatric Disease and Treatment. 4: 371-87. PMID 18728748 DOI: 10.2147/Ndt.S2447 |
0.382 |
|
| 2008 |
Serulle Y, Arancio O, Ziff EB. A role for cGMP-dependent protein kinase II in AMPA receptor trafficking and synaptic plasticity. Channels (Austin, Tex.). 2: 230-2. PMID 18728399 DOI: 10.1016/J.Neures.2009.09.1657 |
0.379 |
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| 2008 |
Trinchese F, Fa' M, Liu S, Zhang H, Hidalgo A, Schmidt SD, Yamaguchi H, Yoshii N, Mathews PM, Nixon RA, Arancio O. Inhibition of calpains improves memory and synaptic transmission in a mouse model of Alzheimer disease. The Journal of Clinical Investigation. 118: 2796-807. PMID 18596919 DOI: 10.1172/Jci34254 |
0.483 |
|
| 2008 |
Voronov SV, Frere SG, Giovedi S, Pollina EA, Borel C, Zhang H, Schmidt C, Akeson EC, Wenk MR, Cimasoni L, Arancio O, Davisson MT, Antonarakis SE, Gardiner K, De Camilli P, et al. Synaptojanin 1-linked phosphoinositide dyshomeostasis and cognitive deficits in mouse models of Down's syndrome. Proceedings of the National Academy of Sciences of the United States of America. 105: 9415-20. PMID 18591654 DOI: 10.1073/Pnas.0803756105 |
0.337 |
|
| 2008 |
Liu L, Orozco IJ, Planel E, Wen Y, Bretteville A, Krishnamurthy P, Wang L, Herman M, Figueroa H, Yu WH, Arancio O, Duff K. A transgenic rat that develops Alzheimer's disease-like amyloid pathology, deficits in synaptic plasticity and cognitive impairment. Neurobiology of Disease. 31: 46-57. PMID 18504134 DOI: 10.1016/J.Nbd.2008.03.005 |
0.762 |
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| 2008 |
Muhammad A, Flores I, Zhang H, Yu R, Staniszewski A, Planel E, Herman M, Ho L, Kreber R, Honig LS, Ganetzky B, Duff K, Arancio O, Small SA. Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation. Proceedings of the National Academy of Sciences of the United States of America. 105: 7327-32. PMID 18480253 DOI: 10.1073/Pnas.0802545105 |
0.46 |
|
| 2008 |
Berman DE, Dall'Armi C, Voronov SV, McIntire LB, Zhang H, Moore AZ, Staniszewski A, Arancio O, Kim TW, Di Paolo G. Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism. Nature Neuroscience. 11: 547-54. PMID 18391946 DOI: 10.1038/Nn.2100 |
0.488 |
|
| 2008 |
Origlia N, Righi M, Capsoni S, Cattaneo A, Fang F, Stern DM, Chen JX, Schmidt AM, Arancio O, Yan SD, Domenici L. Receptor for advanced glycation end product-dependent activation of p38 mitogen-activated protein kinase contributes to amyloid-beta-mediated cortical synaptic dysfunction. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 3521-30. PMID 18367618 DOI: 10.1523/Jneurosci.0204-08.2008 |
0.512 |
|
| 2008 |
Matsuoka Y, Jouroukhin Y, Gray AJ, Ma L, Hirata-Fukae C, Li HF, Feng L, Lecanu L, Walker BR, Planel E, Arancio O, Gozes I, Aisen PS. A neuronal microtubule-interacting agent, NAPVSIPQ, reduces tau pathology and enhances cognitive function in a mouse model of Alzheimer's disease. The Journal of Pharmacology and Experimental Therapeutics. 325: 146-53. PMID 18199809 DOI: 10.1124/Jpet.107.130526 |
0.397 |
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| 2008 |
Arancio O, Puzzo D, Privitera L, Leznik E, Fa M, Staniszewski A, Palmeri A. O4-06-03: Amyloid-beta peptide is a positive modulator of synaptic plasticity and memory Alzheimer's & Dementia. 4: T196-T197. DOI: 10.1016/J.Jalz.2008.05.547 |
0.404 |
|
| 2008 |
Small S, Duff K, Arancio O, Ganetzky B, Honig L. O3-01-03: Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and Abeta accumulation Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.407 |
0.376 |
|
| 2008 |
Arancio O. S2-02-04: Amyloid-beta: From physiology to pathology Alzheimer's & Dementia. 4: T125-T125. DOI: 10.1016/J.Jalz.2008.05.279 |
0.331 |
|
| 2008 |
Leznik E, Trinchese F, Ninan I, Liu S, Arancio O. P3-393: Prolonged exposure to amyloid-β at physiologically relevant levels enhances basal synaptic transmission, but blocks plasticity in the hippocampus Alzheimer's & Dementia. 4: T636-T637. DOI: 10.1016/J.Jalz.2008.05.1963 |
0.417 |
|
| 2007 |
Chen X, Walker DG, Schmidt AM, Arancio O, Lue LF, Yan SD. RAGE: a potential target for Abeta-mediated cellular perturbation in Alzheimer's disease. Current Molecular Medicine. 7: 735-42. PMID 18331231 DOI: 10.2174/156652407783220741 |
0.439 |
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| 2007 |
Echeverria V, Berman DE, Arancio O. Oligomers of beta-amyloid peptide inhibit BDNF-induced arc expression in cultured cortical Neurons. Current Alzheimer Research. 4: 518-21. PMID 18220514 DOI: 10.2174/156720507783018190 |
0.54 |
|
| 2007 |
Serulle Y, Zhang S, Ninan I, Puzzo D, McCarthy M, Khatri L, Arancio O, Ziff EB. A GluR1-cGKII interaction regulates AMPA receptor trafficking. Neuron. 56: 670-88. PMID 18031684 DOI: 10.1016/J.Neuron.2007.09.016 |
0.349 |
|
| 2007 |
Liu S, Fa M, Ninan I, Trinchese F, Dauer W, Arancio O. Alpha-synuclein involvement in hippocampal synaptic plasticity: role of NO, cGMP, cGK and CaMKII. The European Journal of Neuroscience. 25: 3583-96. PMID 17610578 DOI: 10.1111/J.1460-9568.2007.05569.X |
0.358 |
|
| 2007 |
Arancio O, Chao MV. Neurotrophins, synaptic plasticity and dementia. Current Opinion in Neurobiology. 17: 325-30. PMID 17419049 DOI: 10.1016/J.Conb.2007.03.013 |
0.496 |
|
| 2006 |
Puzzo D, Palmeri A, Arancio O. Involvement of the nitric oxide pathway in synaptic dysfunction following amyloid elevation in Alzheimer's disease. Reviews in the Neurosciences. 17: 497-523. PMID 17180876 DOI: 10.1515/Revneuro.2006.17.5.497 |
0.523 |
|
| 2006 |
Ninan I, Liu S, Rabinowitz D, Arancio O. Early presynaptic changes during plasticity in cultured hippocampal neurons. The Embo Journal. 25: 4361-71. PMID 16957772 DOI: 10.1038/Sj.Emboj.7601318 |
0.383 |
|
| 2006 |
Gong B, Cao Z, Zheng P, Vitolo OV, Liu S, Staniszewski A, Moolman D, Zhang H, Shelanski M, Arancio O. Ubiquitin hydrolase Uch-L1 rescues beta-amyloid-induced decreases in synaptic function and contextual memory. Cell. 126: 775-88. PMID 16923396 DOI: 10.1016/J.Cell.2006.06.046 |
0.472 |
|
| 2006 |
Puzzo D, Arancio O. Fibrillar beta-amyloid impairs the late phase of long term potentiation. Current Alzheimer Research. 3: 179-83. PMID 16842092 DOI: 10.2174/156720506777632871 |
0.48 |
|
| 2006 |
Yano H, Ninan I, Zhang H, Milner TA, Arancio O, Chao MV. BDNF-mediated neurotransmission relies upon a myosin VI motor complex. Nature Neuroscience. 9: 1009-18. PMID 16819522 DOI: 10.1038/Nn1730 |
0.416 |
|
| 2006 |
Moretti P, Levenson JM, Battaglia F, Atkinson R, Teague R, Antalffy B, Armstrong D, Arancio O, Sweatt JD, Zoghbi HY. Learning and memory and synaptic plasticity are impaired in a mouse model of Rett syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 319-27. PMID 16399702 DOI: 10.1523/Jneurosci.2623-05.2006 |
0.449 |
|
| 2006 |
Puzzo D, Staniszewski A, Deng SX, Liu S, Palmeri A, Landry DW, Arancio O. P1-068: Synaptic and cognitive impairment in an amyloid-depositing mouse model after sildenafil treatment Alzheimer's & Dementia. 2: S114-S115. DOI: 10.1016/J.Jalz.2006.05.443 |
0.419 |
|
| 2006 |
Gong B, Cao Z, Zheng P, Vitolo O, Staniszewski A, Liu S, Moolman D, Zhang H, Shelanski M, Arancio O. P1-043: UCH-L1 is a critical regulator of synaptic and memory functions following amyloid elevation Alzheimer's & Dementia. 2: S106-S107. DOI: 10.1016/J.Jalz.2006.05.418 |
0.421 |
|
| 2006 |
Domenici L, Origlia N, Capsoni S, Cattaneo A, Arancio O, Yan SD. P3-427: Abeta (1-42) impairs LTP in mouse neocortex through rage mediated activation of p38 map kinase Alzheimer's & Dementia. 2: S501-S502. DOI: 10.1016/J.Jalz.2006.05.1698 |
0.342 |
|
| 2005 |
Puzzo D, Vitolo O, Trinchese F, Jacob JP, Palmeri A, Arancio O. Amyloid-beta peptide inhibits activation of the nitric oxide/cGMP/cAMP-responsive element-binding protein pathway during hippocampal synaptic plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6887-97. PMID 16033898 DOI: 10.1523/Jneurosci.5291-04.2005 |
0.476 |
|
| 2005 |
Zhang H, Gong B, Liu S, Fa' M, Ninan I, Staniszewski A, Arancio O. Synaptic fatigue is more pronounced in the APP/PS1 transgenic mouse model of Alzheimer's disease. Current Alzheimer Research. 2: 137-40. PMID 15974910 DOI: 10.2174/1567205053585936 |
0.487 |
|
| 2005 |
Takuma K, Yao J, Huang J, Xu H, Chen X, Luddy J, Trillat AC, Stern DM, Arancio O, Yan SS. ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 597-8. PMID 15665036 DOI: 10.1096/Fj.04-2582Fje |
0.393 |
|
| 2004 |
Gong B, Vitolo OV, Trinchese F, Liu S, Shelanski M, Arancio O. Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment. The Journal of Clinical Investigation. 114: 1624-34. PMID 15578094 DOI: 10.1172/Jci22831 |
0.528 |
|
| 2004 |
Liu S, Ninan I, Antonova I, Battaglia F, Trinchese F, Narasanna A, Kolodilov N, Dauer W, Hawkins RD, Arancio O. alpha-Synuclein produces a long-lasting increase in neurotransmitter release. The Embo Journal. 23: 4506-16. PMID 15510220 DOI: 10.1038/Sj.Emboj.7600451 |
0.34 |
|
| 2004 |
Arancio O, Zhang HP, Chen X, Lin C, Trinchese F, Puzzo D, Liu S, Hegde A, Yan SF, Stern A, Luddy JS, Lue LF, Walker DG, Roher A, Buttini M, et al. RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice. The Embo Journal. 23: 4096-105. PMID 15457210 DOI: 10.1038/Sj.Emboj.7600415 |
0.477 |
|
| 2004 |
Veeranna, Kaji T, Boland B, Odrljin T, Mohan P, Basavarajappa BS, Peterhoff C, Cataldo A, Rudnicki A, Amin N, Li BS, Pant HC, Hungund BL, Arancio O, Nixon RA. Calpain mediates calcium-induced activation of the erk1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease. The American Journal of Pathology. 165: 795-805. PMID 15331404 DOI: 10.1016/S0002-9440(10)63342-1 |
0.397 |
|
| 2004 |
Trinchese F, Liu S, Ninan I, Puzzo D, Jacob JP, Arancio O. Cell cultures from animal models of Alzheimer's disease as a tool for faster screening and testing of drug efficacy. Journal of Molecular Neuroscience : Mn. 24: 15-21. PMID 15314245 DOI: 10.1385/Jmn:24:1:015 |
0.399 |
|
| 2004 |
Trinchese F, Liu S, Battaglia F, Walter S, Mathews PM, Arancio O. Progressive age-related development of Alzheimer-like pathology in APP/PS1 mice. Annals of Neurology. 55: 801-14. PMID 15174014 DOI: 10.1002/Ana.20101 |
0.508 |
|
| 2004 |
Lustbader JW, Cirilli M, Lin C, Xu HW, Takuma K, Wang N, Caspersen C, Chen X, Pollak S, Chaney M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, ... ... Arancio O, et al. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science (New York, N.Y.). 304: 448-52. PMID 15087549 DOI: 10.1126/Science.1091230 |
0.406 |
|
| 2004 |
Ninan I, Arancio O. Presynaptic CaMKII is necessary for synaptic plasticity in cultured hippocampal neurons. Neuron. 42: 129-41. PMID 15066270 DOI: 10.1016/S0896-6273(04)00143-6 |
0.472 |
|
| 2004 |
Trinchese F, Ninan I, Liu S, Arancio O. P3-323 Alzheimer Aβ increases neuro-transmitter release and blocks synaptic plasticity in hippocampal cultures Neurobiology of Aging. 25: S447. DOI: 10.1016/S0197-4580(04)81473-8 |
0.464 |
|
| 2004 |
Gong B, Vitolo O, Shelanski M, Arancio O. P3-311 Beta-amyloid protein causes impairment of the ubiquitin-proteasome pathway and synaptic plasticity Neurobiology of Aging. 25: S443-S444. DOI: 10.1016/S0197-4580(04)81461-1 |
0.448 |
|
| 2004 |
Veeranna, Kaji T, Boland B, Odrljin T, Mohan P, Basavarajappa BS, Peterhoff C, Cataldo AM, Rudnicki A, Li BS, Pant HC, Hungund BL, Arancio O, Nixon RA. P1-272 Calpain mediates calcium-induced activation of the ERK 1,2 MAPK pathway and cytoskeletal phosphorylation in neurons: relevance to Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80585-2 |
0.369 |
|
| 2004 |
Yao J, Takuma K, Xu HW, Wang C, Stern D, Arancio O, Yan SD. O3-04-08 Role of ABAD in Aβ-mediated mitochondrial dysfunction in Alzheimer disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80205-7 |
0.345 |
|
| 2003 |
Battaglia F, Trinchese F, Liu S, Walter S, Nixon RA, Arancio O. Calpain inhibitors, a treatment for Alzheimer's disease: position paper. Journal of Molecular Neuroscience : Mn. 20: 357-62. PMID 14501020 DOI: 10.1385/Jmn:20:3:357 |
0.46 |
|
| 2003 |
Petrone A, Battaglia F, Wang C, Dusa A, Su J, Zagzag D, Bianchi R, Casaccia-Bonnefil P, Arancio O, Sap J. Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. The Embo Journal. 22: 4121-31. PMID 12912911 DOI: 10.1093/Emboj/Cdg399 |
0.426 |
|
| 2003 |
Sant'Angelo A, Trinchese F, Arancio O. Usefulness of behavioral and electrophysiological studies in transgenic models of Alzheimer's disease Neurochemical Research. 28: 1009-1015. PMID 12737525 DOI: 10.1023/A:1023251005197 |
0.411 |
|
| 2002 |
Vitolo OV, Sant'Angelo A, Costanzo V, Battaglia F, Arancio O, Shelanski M. Amyloid β-peptide inhibition of the PKA/CREB pathway and long-term potentiation: Reversibility by drugs that enhance cAMP signaling Proceedings of the National Academy of Sciences of the United States of America. 99: 13217-13221. PMID 12244210 DOI: 10.1073/Pnas.172504199 |
0.492 |
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| 2002 |
Di Rosa G, Odrijin T, Nixon RA, Arancio O. Calpain inhibitors: a treatment for Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 19: 135-41. PMID 12212771 DOI: 10.1007/s12031-002-0024-4 |
0.402 |
|
| 2001 |
Antonova I, Arancio O, Trillat AC, Wang HG, Zablow L, Udo H, Kandel ER, Hawkins RD. Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation. Science (New York, N.Y.). 294: 1547-50. PMID 11641465 DOI: 10.1126/Science.1066273 |
0.552 |
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| 2001 |
Arancio O, Antonova I, Gambaryan S, Lohmann SM, Wood JS, Lawrence DS, Hawkins RD. Presynaptic role of cGMP-dependent protein kinase during long-lasting potentiation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 143-9. PMID 11150330 DOI: 10.1523/Jneurosci.21-01-00143.2001 |
0.426 |
|
| 1998 |
Son H, Lu YF, Zhuo M, Arancio O, Kandel ER, Hawkins RD. The specific role of cGMP in hippocampal LTP. Learning & Memory (Cold Spring Harbor, N.Y.). 5: 231-45. PMID 10454367 DOI: 10.1101/Lm.5.3.231 |
0.531 |
|
| 1998 |
Arancio O. Morphological changes associated with long-term potentiation Histology and Histopathology. 13: 1155-1162. PMID 9810507 |
0.33 |
|
| 1996 |
Arancio O, Lev-Ram V, Tsien RY, Kandel ER, Hawkins RD. Nitric oxide acts as a retrograde messenger during long-term potentiation in cultured hippocampal neurons. Journal of Physiology, Paris. 90: 321-2. PMID 9089501 DOI: 10.1016/S0928-4257(97)87907-7 |
0.541 |
|
| 1996 |
Arancio O, Kiebler M, Lee CJ, Lev-Ram V, Tsien RY, Kandel ER, Hawkins RD. Nitric oxide acts directly in the presynaptic neuron to produce long-term potentiation in cultured hippocampal neurons. Cell. 87: 1025-35. PMID 8978607 DOI: 10.1016/S0092-8674(00)81797-3 |
0.547 |
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| 1996 |
López-GarcÃa JC, Arancio O, Kandel ER, Baranes D. A presynaptic locus for long-term potentiation of elementary synaptic transmission at mossy fiber synapses in culture. Proceedings of the National Academy of Sciences of the United States of America. 93: 4712-7. PMID 8643468 DOI: 10.1073/Pnas.93.10.4712 |
0.556 |
|
| 1995 |
Arancio O, Kandel ER, Hawkins RD. Activity-dependent long-term enhancement of transmitter release by presynaptic 3',5'-cyclic GMP in cultured hippocampal neurons. Nature. 376: 74-80. PMID 7596438 DOI: 10.1038/376074A0 |
0.584 |
|
| 1994 |
Hawkins RD, Zhuo M, Arancio O. Nitric oxide and carbon monoxide as possible retrograde messengers in hippocampal long-term potentiation Journal of Neurobiology. 25: 652-665. PMID 8071665 DOI: 10.1002/neu.480250607 |
0.314 |
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| 1994 |
Arancio O, Korn H, Gulyas A, Freund T, Miles R. Excitatory synaptic connections onto rat hippocampal inhibitory cells may involve a single transmitter release site. The Journal of Physiology. 481: 395-405. PMID 7738832 DOI: 10.1113/Jphysiol.1994.Sp020448 |
0.36 |
|
| 1993 |
Arancio O, Yoshimura M, Murase K, MacDermott AB. The distribution of excitatory amino acid receptors on acutely dissociated dorsal horn neurons from postnatal rats. Neuroscience. 52: 159-67. PMID 8433804 DOI: 10.1016/0306-4522(93)90190-Q |
0.337 |
|
| 1991 |
O'Dell TJ, Hawkins RD, Kandel ER, Arancio O. Tests of the roles of two diffusible substances in long-term potentiation: evidence for nitric oxide as a possible early retrograde messenger. Proceedings of the National Academy of Sciences of the United States of America. 88: 11285-9. PMID 1684863 DOI: 10.1073/Pnas.88.24.11285 |
0.519 |
|
| 1990 |
MacDermott AB, Reichling DB, Arancio O. Mechanisms underlying excitatory amino acid-evoked calcium entry in cultured neurons from the embryonic rat spinal cord. Advances in Experimental Medicine and Biology. 268: 117-24. PMID 1963736 DOI: 10.1007/978-1-4684-5769-8_14 |
0.326 |
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