Knut Woltjen - Publications

Affiliations: 
CiRA, Kyoto University 
Area:
genome engineering, reprogramming, stem cells

41/70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Okubo T, Rivron N, Kabata M, Masaki H, Kishimoto K, Semi K, Nakajima-Koyama M, Kunitomi H, Kaswandy B, Sato H, Nakauchi H, Woltjen K, Saitou M, Sasaki E, Yamamoto T, et al. Publisher Correction: Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. 626: E21. PMID 38347193 DOI: 10.1038/s41586-024-07166-w  0.385
2023 Okubo T, Rivron N, Kabata M, Masaki H, Kishimoto K, Semi K, Nakajima-Koyama M, Kunitomi H, Kaswandy B, Sato H, Nakauchi H, Woltjen K, Saitou M, Sasaki E, Yamamoto T, et al. Hypoblast from human pluripotent stem cells regulates epiblast development. Nature. PMID 38052228 DOI: 10.1038/s41586-023-06871-2  0.362
2023 Otomo J, Woltjen K, Sakurai H. Uniform transgene activation in Tet-On systems depends on sustained rtTA expression. Iscience. 26: 107685. PMID 37701566 DOI: 10.1016/j.isci.2023.107685  0.361
2023 Kubiura-Ichimaru M, Penfold C, Kojima K, Dollet C, Yabukami H, Semi K, Takashima Y, Boroviak T, Kawaji H, Woltjen K, Minoda A, Sasaki E, Watanabe T. mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells. Stem Cell Reports. 18: 1987-2002. PMID 37683645 DOI: 10.1016/j.stemcr.2023.08.006  0.411
2022 Ueda T, Shiina S, Iriguchi S, Terakura S, Kawai Y, Kabai R, Sakamoto S, Watanabe A, Ohara K, Wang B, Xu H, Minagawa A, Hotta A, Woltjen K, Uemura Y, et al. Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells. Nature Biomedical Engineering. 7: 24-37. PMID 36509913 DOI: 10.1038/s41551-022-00969-0  0.304
2021 Taguchi J, Shibata H, Kabata M, Kato M, Fukuda K, Tanaka A, Ohta S, Ukai T, Mitsunaga K, Yamada Y, Nagaoka SI, Yamazawa S, Ohnishi K, Woltjen K, Ushiku T, et al. DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency. Nature Communications. 12: 5041. PMID 34413299 DOI: 10.1038/s41467-021-25249-4  0.325
2021 Io S, Kabata M, Iemura Y, Semi K, Morone N, Minagawa A, Wang B, Okamoto I, Nakamura T, Kojima Y, Iwatani C, Tsuchiya H, Kaswandy B, Kondoh E, Kaneko S, ... Woltjen K, et al. Capturing human trophoblast development with naive pluripotent stem cells in vitro. Cell Stem Cell. PMID 33831365 DOI: 10.1016/j.stem.2021.03.013  0.312
2020 Maurissen TL, Woltjen K. Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation. Nature Communications. 11: 2876. PMID 32513994 DOI: 10.1038/s41467-020-16643-5  0.316
2020 Matsuda M, Yamanaka Y, Uemura M, Osawa M, Saito MK, Nagahashi A, Nishio M, Guo L, Ikegawa S, Sakurai S, Kihara S, Maurissen TL, Nakamura M, Matsumoto T, Yoshitomi H, ... ... Woltjen K, et al. Recapitulating the human segmentation clock with pluripotent stem cells. Nature. 580: 124-129. PMID 32238941 DOI: 10.1038/s41586-020-2144-9  0.382
2019 Sakakura M, Ohta S, Yagi M, Tanaka A, Norihide J, Woltjen K, Yamamoto T, Yamada Y. Smarcb1 maintains the cellular identity and the chromatin landscapes of mouse embryonic stem cells. Biochemical and Biophysical Research Communications. PMID 31543342 DOI: 10.1016/j.bbrc.2019.09.054  0.358
2019 Komura S, Ito K, Ohta S, Ukai T, Kabata M, Itakura F, Semi K, Matsuda Y, Hashimoto K, Shibata H, Sone M, Jo N, Sekiguchi K, Ohno T, Akiyama H, ... ... Woltjen K, et al. Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas. Nature Communications. 10: 3999. PMID 31488818 DOI: 10.1038/S41467-019-11745-1  0.349
2018 Kagawa H, Shimamoto R, Kim SI, Oceguera-Yanez F, Yamamoto T, Schroeder T, Woltjen K. OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates. Stem Cell Reports. PMID 30639212 DOI: 10.1016/j.stemcr.2018.12.008  0.421
2018 Kim SI, Matsumoto T, Kagawa H, Nakamura M, Hirohata R, Ueno A, Ohishi M, Sakuma T, Soga T, Yamamoto T, Woltjen K. Microhomology-assisted scarless genome editing in human iPSCs. Nature Communications. 9: 939. PMID 29507284 DOI: 10.1038/s41467-018-03044-y  0.339
2017 Kojima Y, Sasaki K, Yokobayashi S, Sakai Y, Nakamura T, Yabuta Y, Nakaki F, Nagaoka S, Woltjen K, Hotta A, Yamamoto T, Saitou M. Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells. Cell Stem Cell. 21: 517-532.e5. PMID 28985527 DOI: 10.1016/J.Stem.2017.09.005  0.374
2017 Kieffer TJ, Woltjen K, Osafune K, Yabe D, Inagaki N. Beta-cell replacement strategies for diabetes. Journal of Diabetes Investigation. PMID 28984038 DOI: 10.1111/jdi.12758  0.318
2016 Komura S, Semi K, Itakura F, Shibata H, Ohno T, Hotta A, Woltjen K, Yamamoto T, Akiyama H, Yamada Y. An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development. Stem Cell Reports. PMID 26997645 DOI: 10.1016/J.Stemcr.2016.02.009  0.319
2015 Oceguera-Yanez F, Kim SI, Matsumoto T, Tan GW, Long X, Hatani T, Kondo T, Ikeya M, Yoshida Y, Inoue H, Woltjen K. Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives. Methods (San Diego, Calif.). PMID 26707206 DOI: 10.1016/j.ymeth.2015.12.012  0.41
2015 Tamaki S, Fukuta M, Sekiguchi K, Jin Y, Nagata S, Hayakawa K, Hineno S, Okamoto T, Watanabe M, Woltjen K, Ikeya M, Kato T, Toguchida J. SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier. Plos One. 10: e0142991. PMID 26571495 DOI: 10.1371/journal.pone.0142991  0.321
2015 Chantzoura E, Skylaki S, Menendez S, Kim SI, Johnsson A, Linnarsson S, Woltjen K, Chambers I, Kaji K. Reprogramming Roadblocks Are System Dependent. Stem Cell Reports. 5: 350-64. PMID 26278041 DOI: 10.1016/J.Stemcr.2015.07.007  0.306
2015 Sasaki K, Yokobayashi S, Nakamura T, Okamoto I, Yabuta Y, Kurimoto K, Ohta H, Moritoki Y, Iwatani C, Tsuchiya H, Nakamura S, Sekiguchi K, Sakuma T, Yamamoto T, Mori T, ... Woltjen K, et al. Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells. Cell Stem Cell. 17: 178-94. PMID 26189426 DOI: 10.1016/j.stem.2015.06.014  0.396
2015 Woltjen K, Kim SI, Nagy A. The piggyBac Transposon as a Platform Technology for Somatic Cell Reprogramming Studies in Mouse. Methods in Molecular Biology (Clifton, N.J.). PMID 26126450 DOI: 10.1007/7651_2015_274  0.55
2015 Kim SI, Oceguera-Yanez F, Sakurai C, Nakagawa M, Yamanaka S, Woltjen K. Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons. Methods in Molecular Biology (Clifton, N.J.). PMID 26025620 DOI: 10.1007/7651_2015_251  0.463
2015 Shoji E, Woltjen K, Sakurai H. Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells. Methods in Molecular Biology (Clifton, N.J.). PMID 25971915 DOI: 10.1007/7651_2015_257  0.416
2014 Ohnishi K, Semi K, Yamamoto T, Shimizu M, Tanaka A, Mitsunaga K, Okita K, Osafune K, Arioka Y, Maeda T, Soejima H, Moriwaki H, Yamanaka S, Woltjen K, Yamada Y. Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation. Cell. 156: 663-77. PMID 24529372 DOI: 10.1016/j.cell.2014.01.005  0.301
2013 Yamashita A, Liu S, Woltjen K, Thomas B, Meng G, Hotta A, Takahashi K, Ellis J, Yamanaka S, Rancourt DE. Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells. Scientific Reports. 3: 1978. PMID 23760219 DOI: 10.1038/srep01978  0.586
2013 Tanaka A, Woltjen K, Miyake K, Hotta A, Ikeya M, Yamamoto T, Nishino T, Shoji E, Sehara-Fujisawa A, Manabe Y, Fujii N, Hanaoka K, Era T, Yamashita S, Isobe K, et al. Efficient and reproducible myogenic differentiation from human iPS cells: prospects for modeling Miyoshi Myopathy in vitro. Plos One. 8: e61540. PMID 23626698 DOI: 10.1371/journal.pone.0061540  0.389
2013 Sakuma T, Hosoi S, Woltjen K, Suzuki K, Kashiwagi K, Wada H, Ochiai H, Miyamoto T, Kawai N, Sasakura Y, Matsuura S, Okada Y, Kawahara A, Hayashi S, Yamamoto T. Efficient TALEN construction and evaluation methods for human cell and animal applications. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 18: 315-26. PMID 23388034 DOI: 10.1111/gtc.12037  0.392
2013 Hayakawa K, Ikeya M, Fukuta M, Woltjen K, Tamaki S, Takahara N, Kato T, Sato S, Otsuka T, Toguchida J. Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells. Biochemical and Biophysical Research Communications. 432: 713-9. PMID 23313505 DOI: 10.1016/j.bbrc.2013.01.003  0.364
2012 Michael IP, Monetti C, Chiu AC, Zhang P, Baba T, Nishino K, Agha-Mohammadi S, Woltjen K, Sung HK, Nagy A. Highly efficient site-specific transgenesis in cancer cell lines. Molecular Cancer. 11: 89. PMID 23231822 DOI: 10.1186/1476-4598-11-89  0.454
2011 Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, et al. An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming. Cell. 147: 132-46. PMID 21924763 DOI: 10.1016/J.Cell.2011.08.023  0.526
2011 Woltjen K, Hämäläinen R, Kibschull M, Mileikovsky M, Nagy A. Transgene-free production of pluripotent stem cells using piggyBac transposons. Methods in Molecular Biology (Clifton, N.J.). 767: 87-103. PMID 21822869 DOI: 10.1007/978-1-61779-201-4_7  0.599
2011 Nagy K, Sung HK, Zhang P, Laflamme S, Vincent P, Agha-Mohammadi S, Woltjen K, Monetti C, Michael IP, Smith LC, Nagy A. Induced pluripotent stem cell lines derived from equine fibroblasts. Stem Cell Reviews. 7: 693-702. PMID 21347602 DOI: 10.1007/S12015-011-9239-5  0.57
2011 Monetti C, Nishino K, Biechele S, Zhang P, Baba T, Woltjen K, Nagy A. PhiC31 integrase facilitates genetic approaches combining multiple recombinases. Methods (San Diego, Calif.). 53: 380-5. PMID 21185379 DOI: 10.1016/J.Ymeth.2010.12.023  0.527
2010 Samavarchi-Tehrani P, Golipour A, David L, Sung HK, Beyer TA, Datti A, Woltjen K, Nagy A, Wrana JL. Functional genomics reveals a BMP-driven mesenchymal-to-epithelial transition in the initiation of somatic cell reprogramming. Cell Stem Cell. 7: 64-77. PMID 20621051 DOI: 10.1016/J.Stem.2010.04.015  0.512
2010 O'Malley J, Woltjen K, Kaji K. New strategies to generate induced pluripotent stem cells. Current Opinion in Biotechnology. 20: 516-21. PMID 19837580 DOI: 10.1016/j.copbio.2009.09.005  0.434
2009 Woltjen K, Stanford WL. Preview. Inhibition of Tgf-beta signaling improves mouse fibroblast reprogramming. Cell Stem Cell. 5: 457-8. PMID 19896434 DOI: 10.1016/J.Stem.2009.10.007  0.351
2009 Woltjen K, Michael IP, Mohseni P, Desai R, Mileikovsky M, Hämäläinen R, Cowling R, Wang W, Liu P, Gertsenstein M, Kaji K, Sung HK, Nagy A. piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells. Nature. 458: 766-70. PMID 19252478 DOI: 10.1038/Nature07863  0.637
2009 Kaji K, Norrby K, Paca A, Mileikovsky M, Mohseni P, Woltjen K. Virus-free induction of pluripotency and subsequent excision of reprogramming factors. Nature. 458: 771-5. PMID 19252477 DOI: 10.1038/nature07864  0.489
2008 Woltjen K, Ito K, Tsuzuki T, Rancourt DE. Orpheus recombination : a comprehensive bacteriophage system for murine targeting vector construction by transplacement. Methods in Molecular Biology (Clifton, N.J.). 435: 79-94. PMID 18370069 DOI: 10.1007/978-1-59745-232-8_6  0.533
2003 Thomas B, Woltjen K, Rancourt DE. Deep screening of recombination proficient bacteriophage libraries. Biotechniques. 34: 36-8, 40. PMID 12545535  0.469
2002 Woltjen K, Unger MW, Rancourt DE. Transplacement mutagenesis. A recombination-based in situ mutagenesis protocol. Methods in Molecular Biology (Clifton, N.J.). 182: 189-207. PMID 11768965  0.516
Low-probability matches (unlikely to be authored by this person)
2023 Gao J, Makiyama T, Yamamoto Y, Kobayashi T, Aoki H, Maurissen TL, Wuriyanghai Y, Kashiwa A, Imamura T, Aizawa T, Huang H, Kohjitani H, Nishikawa M, Chonabayashi K, Fukuyama M, ... ... Woltjen K, et al. Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation. Arrhythmia and Electrophysiology. e011387. PMID 36866681 DOI: 10.1161/CIRCEP.122.011387  0.299
2022 Takahashi K, Okubo C, Nakamura M, Iwasaki M, Kawahara Y, Tabata T, Miyamoto Y, Woltjen K, Yamanaka S. A stress-reduced passaging technique improves the viability of human pluripotent cells. Cell Reports Methods. 2: 100155. PMID 35474962 DOI: 10.1016/j.crmeth.2021.100155  0.293
2015 Kim SI, Oceguera-Yanez F, Hirohata R, Linker S, Okita K, Yamada Y, Yamamoto T, Yamanaka S, Woltjen K. KLF4 N-terminal variance modulates induced reprogramming to pluripotency. Stem Cell Reports. 4: 727-43. PMID 25772473 DOI: 10.1016/j.stemcr.2015.02.004  0.29
2019 Grajcarek J, Monlong J, Nishinaka-Arai Y, Nakamura M, Nagai M, Matsuo S, Lougheed D, Sakurai H, Saito MK, Bourque G, Woltjen K. Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations. Nature Communications. 10: 4856. PMID 31649251 DOI: 10.1038/s41467-019-12829-8  0.289
2023 Niwa R, Sakai K, Lung MSY, Matsumoto T, Mikawa R, Maehana S, Suzuki M, Yamamoto Y, Maurissen TL, Hirabayashi A, Noda T, Kubo M, Gotoh S, Woltjen K. ACE2 knockout hinders SARS-CoV-2 propagation in iPS cell-derived airway and alveolar epithelial cells. Frontiers in Cell and Developmental Biology. 11: 1290876. PMID 38149046 DOI: 10.3389/fcell.2023.1290876  0.282
2022 Ito K, Nagata K, Ohta S, Matsuda Y, Ukai T, Yasuda I, Ota A, Kobayashi R, Kabata M, Sankoda N, Maeda T, Woltjen K, Yang L, Maruyama R, Katayama R, et al. The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets. Cell Reports. 39: 110721. PMID 35476996 DOI: 10.1016/j.celrep.2022.110721  0.276
2017 Hashimoto K, Yamada Y, Semi K, Yagi M, Tanaka A, Itakura F, Aoki H, Kunisada T, Woltjen K, Haga H, Sakai Y, Yamamoto T, Yamada Y. Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior. Proceedings of the National Academy of Sciences of the United States of America. PMID 28057861 DOI: 10.1073/pnas.1614197114  0.274
2018 Shibata H, Komura S, Yamada Y, Sankoda N, Tanaka A, Ukai T, Kabata M, Sakurai S, Kuze B, Woltjen K, Haga H, Ito Y, Kawaguchi Y, Yamamoto T, Yamada Y. In vivo reprogramming drives Kras-induced cancer development. Nature Communications. 9: 2081. PMID 29802314 DOI: 10.1038/s41467-018-04449-5  0.267
2018 Ikeda T, Hikichi T, Miura H, Shibata H, Mitsunaga K, Yamada Y, Woltjen K, Miyamoto K, Hiratani I, Yamada Y, Hotta A, Yamamoto T, Okita K, Masui S. Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs. Nature Communications. 9: 1387. PMID 29643333 DOI: 10.1038/s41467-018-03748-1  0.264
2018 Jo N, Sogabe Y, Yamada Y, Ukai T, Kagawa H, Mitsunaga K, Woltjen K, Yamada Y. Platforms of in vivo genome editing with inducible Cas9 for advanced cancer modeling. Cancer Science. PMID 30588718 DOI: 10.1111/cas.13924  0.251
2015 Matsuda M, Koga M, Woltjen K, Nishida E, Ebisuya M. Synthetic lateral inhibition governs cell-type bifurcation with robust ratios. Nature Communications. 6: 6195. PMID 25652697 DOI: 10.1038/ncomms7195  0.244
2015 Jin Y, Elalaf H, Watanabe M, Tamaki S, Hineno S, Matsunaga K, Woltjen K, Kobayashi Y, Nagata S, Ikeya M, Kato T, Okamoto T, Matsuda S, Toguchida J. Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes. Plos One. 10: e0131998. PMID 26161668 DOI: 10.1371/journal.pone.0131998  0.242
2014 Sakuma T, Woltjen K. Nuclease-mediated genome editing: At the front-line of functional genomics technology Development Growth and Differentiation. 56: 2-13. PMID 24387662 DOI: 10.1111/dgd.12111  0.228
2017 Sone M, Morone N, Nakamura T, Tanaka A, Okita K, Woltjen K, Nakagawa M, Heuser JE, Yamada Y, Yamanaka S, Yamamoto T. Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency. Cell Metabolism. 25: 1103-1117.e6. PMID 28467928 DOI: 10.1016/j.cmet.2017.04.017  0.225
2013 Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD. Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell. 13: 564-76. PMID 24209760 DOI: 10.1016/J.Stem.2013.10.002  0.214
2019 Yagi M, Kabata M, Ukai T, Ohta S, Tanaka A, Shimada Y, Sugimoto M, Araki K, Okita K, Woltjen K, Hochedlinger K, Yamamoto T, Yamada Y. De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency. Stem Cell Reports. 12: 1113-1128. PMID 31056481 DOI: 10.1016/j.stemcr.2019.04.008  0.213
2022 Oceguera-Yanez F, Avila-Robinson A, Woltjen K. Differentiation of pluripotent stem cells for modeling human skin development and potential applications. Frontiers in Cell and Developmental Biology. 10: 1030339. PMID 36506084 DOI: 10.3389/fcell.2022.1030339  0.207
2021 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y. Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nature Communications. 12: 560. PMID 33495473 DOI: 10.1038/s41467-021-20906-0  0.201
2019 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A. Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Reports. 29: 603-616.e5. PMID 31618630 DOI: 10.1016/J.Celrep.2019.09.019  0.184
2017 Hirosawa M, Fujita Y, Parr CJC, Hayashi K, Kashida S, Hotta A, Woltjen K, Saito H. Cell-type-specific genome editing with a microRNA-responsive CRISPR-Cas9 switch. Nucleic Acids Research. PMID 28525578 DOI: 10.1093/nar/gkx309  0.18
2023 Saito MK, Osawa M, Tsuchida N, Shiraishi K, Niwa A, Woltjen K, Asaka I, Ogata K, Ito S, Kobayashi S, Yamanaka S. A disease-specific iPS cell resource for studying rare and intractable diseases. Inflammation and Regeneration. 43: 43. PMID 37684663 DOI: 10.1186/s41232-023-00294-2  0.174
2016 Woltjen K, Yamamoto T, Kokubu C, Takeda J. Report on the Conference on Transposition and Genome Engineering 2015 (TGE 2015): advancing cutting-edge genomics technology in the ancient city of Nara. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. PMID 27028186 DOI: 10.1111/gtc.12367  0.154
2017 Kondo T, Imamura K, Funayama M, Tsukita K, Miyake M, Ohta A, Woltjen K, Nakagawa M, Asada T, Arai T, Kawakatsu S, Izumi Y, Kaji R, Iwata N, Inoue H. iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease. Cell Reports. 21: 2304-2312. PMID 29166618 DOI: 10.1016/j.celrep.2017.10.109  0.149
2020 Reinhardt A, Kagawa H, Woltjen K. N-Terminal Amino Acids Determine KLF4 Protein Stability in 2A Peptide-Linked Polycistronic Reprogramming Constructs. Stem Cell Reports. 14: 520-527. PMID 32109368 DOI: 10.1016/j.stemcr.2020.01.014  0.146
2017 Imamura K, Izumi Y, Watanabe A, Tsukita K, Woltjen K, Yamamoto T, Hotta A, Kondo T, Kitaoka S, Ohta A, Tanaka A, Watanabe D, Morita M, Takuma H, Tamaoka A, et al. The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis. Science Translational Medicine. 9. PMID 28539470 DOI: 10.1126/Scitranslmed.Aaf3962  0.13
2024 Maurissen TL, Kawatou M, López-Dávila V, Minatoya K, Yamashita JK, Woltjen K. Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues. Scientific Reports. 14: 2586. PMID 38297132 DOI: 10.1038/s41598-024-52871-1  0.12
2023 Kawasaki S, Ono H, Hirosawa M, Kuwabara T, Sumi S, Lee S, Woltjen K, Saito H. Programmable mammalian translational modulators by CRISPR-associated proteins. Nature Communications. 14: 2243. PMID 37076490 DOI: 10.1038/s41467-023-37540-7  0.114
2022 Kashiwa A, Makiyama T, Kohjitani H, Maurissen TL, Ishikawa T, Yamamoto Y, Wuriyanghai Y, Gao J, Huang H, Imamura T, Aizawa T, Nishikawa M, Chonabayashi K, Mishima H, Ohno S, ... ... Woltjen K, et al. Disrupted Cav1.2 selectivity causes overlapping long QT and Brugada syndrome phenotypes in the CACNA1C-E1115K iPS cell model. Heart Rhythm. PMID 36007726 DOI: 10.1016/j.hrthm.2022.08.021  0.104
2018 Woltjen K, Bortvin A. Editorial overview: Embroidering the canvas of life. Current Opinion in Genetics & Development. 52: ii-iv. PMID 30470343 DOI: 10.1016/J.Gde.2018.11.002  0.01
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