Year |
Citation |
Score |
2022 |
Cameron D, Soto-Mota A, Willis DR, Ellis J, Procter NEK, Greenwood R, Saunders N, Schulte RF, Vassiliou VS, Tyler DJ, Schmid AI, Rodgers CT, Malcolm PN, Clarke K, Frenneaux MP, et al. Evaluation of Acute Supplementation With the Ketone Ester ()-3-Hydroxybutyl-(R)-3-Hydroxybutyrate (deltaG) in Healthy Volunteers by Cardiac and Skeletal Muscle P Magnetic Resonance Spectroscopy. Frontiers in Physiology. 13: 793987. PMID 35173629 DOI: 10.3389/fphys.2022.793987 |
0.307 |
|
2020 |
Kadir AA, Clarke K, Evans RD. Cardiac ketone body metabolism. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165739. PMID 32084511 DOI: 10.1016/j.bbadis.2020.165739 |
0.487 |
|
2018 |
Maack C, Lehrke M, Backs J, Heinzel FR, Hulot JS, Marx N, Paulus WJ, Rossignol P, Taegtmeyer H, Bauersachs J, Bayes-Genis A, Brutsaert D, Bugger H, Clarke K, Cosentino F, et al. Heart failure and diabetes: metabolic alterations and therapeutic interventions: a state-of-the-art review from the Translational Research Committee of the Heart Failure Association-European Society of Cardiology. European Heart Journal. PMID 30295797 DOI: 10.1093/Eurheartj/Ehy596 |
0.354 |
|
2018 |
Zhang W, Sang AE, Ten Hove M, Neubauer S, Clarke K. Data on uncoupling protein-3 levels, hypoxia, low flow ischemia, and insulin stimulation in dystrophin-deficient mouse hearts. Data in Brief. 20: 277-280. PMID 30148195 DOI: 10.1016/j.dib.2018.08.010 |
0.341 |
|
2018 |
Zhang W, Ten Hove M, Schneider JE, Clarke K. Data on triiodothyronine treated peroxisome proliferator-activated receptor-alpha-null mouse hearts using magnetic resonance imaging and magnetic resonance spectroscopy. Data in Brief. 20: 250-253. PMID 30140721 DOI: 10.1016/j.dib.2018.08.009 |
0.349 |
|
2017 |
Mansor LS, Sousa Fialho MDL, Yea G, Coumans WA, West JA, Kerr M, Carr CA, Luiken JJFP, Glatz JFC, Evans RD, Griffin JL, Tyler DJ, Clarke K, Heather LC. Inhibition of sarcolemmal FAT/CD36 by sulfo-N-succinimidyl oleate rapidly corrects metabolism and restores function in the diabetic heart following hypoxia/reoxygenation. Cardiovascular Research. PMID 28419197 DOI: 10.1093/cvr/cvx045 |
0.326 |
|
2016 |
Slingo M, Cole MA, Carr CA, Curtis MK, Dodd MS, Giles L, Heather LC, Tyler DJ, Clarke K, Robbins PA. The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high energy phosphate metabolism. American Journal of Physiology. Heart and Circulatory Physiology. ajpheart.00912.2015. PMID 27422990 DOI: 10.1152/ajpheart.00912.2015 |
0.485 |
|
2016 |
Cole MA, Abd Jamil AH, Heather LC, Murray AJ, Sutton ER, Slingo M, Sebag-Montefiore L, Tan SC, Aksentijević D, Gildea OS, Stuckey DJ, Yeoh KK, Carr CA, Evans RD, Aasum E, ... ... Clarke K, et al. On the pivotal role of PPARα in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 27103577 DOI: 10.1096/Fj.201500094R |
0.627 |
|
2015 |
Mansor LS, Mehta K, Aksentijevic D, Carr CA, Lund T, Cole MA, Page LL, Fialho MD, Shattock MJ, Aasum E, Clarke K, Tyler DJ, Heather LC. Increased oxidative metabolism following hypoxia in the type 2 diabetic heart, despite normal hypoxia signalling and metabolic adaptation. The Journal of Physiology. PMID 26574233 DOI: 10.1113/JP271242 |
0.611 |
|
2015 |
Levelt E, Mahmod M, Piechnik SK, Ariga R, Francis JM, Rodgers CT, Clarke WT, Sabharwal N, Schneider JE, Karamitsos TD, Clarke K, Rider OJ, Neubauer S. Relationship between Left Ventricular Structural and Metabolic Remodelling in Type 2 Diabetes Mellitus. Diabetes. PMID 26438611 DOI: 10.2337/db15-0627 |
0.376 |
|
2015 |
Levelt E, Rodgers CT, Clarke WT, Mahmod M, Ariga R, Francis JM, Liu A, Wijesurendra RS, Dass S, Sabharwal N, Robson MD, Holloway CJ, Rider OJ, Clarke K, Karamitsos TD, et al. Cardiac energetics, oxygenation, and perfusion during increased workload in patients with type 2 diabetes mellitus. European Heart Journal. PMID 26392437 DOI: 10.1093/eurheartj/ehv442 |
0.303 |
|
2015 |
Dass S, Holloway CJ, Cochlin LE, Rider OJ, Mahmod M, Robson M, Sever E, Clarke K, Watkins H, Ashrafian H, Karamitsos TD, Neubauer S. No Evidence of Myocardial Oxygen Deprivation in Non-Ischemic Heart Failure. Circulation. Heart Failure. PMID 26333351 DOI: 10.1161/CIRCHEARTFAILURE.114.002169 |
0.351 |
|
2015 |
Betts CA, Saleh AF, Carr CA, Muses S, Wells KE, Hammond SM, Godfrey C, McClorey G, Woffindale C, Clarke K, Wells DJ, Gait MJ, Wood MJ. Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy. Scientific Reports. 5: 11632. PMID 26113184 DOI: 10.1038/Srep11632 |
0.31 |
|
2015 |
Dass S, Cochlin LE, Suttie JJ, Holloway CJ, Rider OJ, Carden L, Tyler DJ, Karamitsos TD, Clarke K, Neubauer S, Watkins H. Exacerbation of cardiac energetic impairment during exercise in hypertrophic cardiomyopathy: a potential mechanism for diastolic dysfunction. European Heart Journal. 36: 1547-54. PMID 25990345 DOI: 10.1093/eurheartj/ehv120 |
0.326 |
|
2015 |
Betts CA, Saleh AF, Carr CA, Hammond SM, Coenen-Stass AM, Godfrey C, McClorey G, Varela MA, Roberts TC, Clarke K, Gait MJ, Wood MJ. Prevention of exercised induced cardiomyopathy following Pip-PMO treatment in dystrophic mdx mice. Scientific Reports. 5: 8986. PMID 25758104 DOI: 10.1038/Srep08986 |
0.365 |
|
2015 |
Seymour AM, Giles L, Ball V, Miller JJ, Clarke K, Carr CA, Tyler DJ. In vivo assessment of cardiac metabolism and function in the abdominal aortic banding model of compensated cardiac hypertrophy. Cardiovascular Research. 106: 249-60. PMID 25750189 DOI: 10.1093/cvr/cvv101 |
0.463 |
|
2014 |
Carr CA, Ball D, Tyler DJ, Bushell A, Sykes A, Clarke K, Evans RD. Varying degrees of ventricular unloading in the heterotopic rat heart transplant model demonstrated by magnetic resonance imaging. International Journal of Biomedical Science : Ijbs. 10: 223-8. PMID 25598751 |
0.36 |
|
2014 |
Dodd MS, Atherton HJ, Carr CA, Stuckey DJ, West JA, Griffin JL, Radda GK, Clarke K, Heather LC, Tyler DJ. Impaired in vivo mitochondrial Krebs cycle activity after myocardial infarction assessed using hyperpolarized magnetic resonance spectroscopy. Circulation. Cardiovascular Imaging. 7: 895-904. PMID 25201905 DOI: 10.1161/Circimaging.114.001857 |
0.443 |
|
2014 |
Desrois M, Kober F, Lan C, Dalmasso C, Cole M, Clarke K, Cozzone PJ, Bernard M. Effect of isoproterenol on myocardial perfusion, function, energy metabolism and nitric oxide pathway in the rat heart - a longitudinal MR study. Nmr in Biomedicine. 27: 529-38. PMID 24677605 DOI: 10.1002/nbm.3088 |
0.388 |
|
2013 |
Ball DR, Cruickshank R, Carr CA, Stuckey DJ, Lee P, Clarke K, Tyler DJ. Metabolic imaging of acute and chronic infarction in the perfused rat heart using hyperpolarised [1-13C]pyruvate. Nmr in Biomedicine. 26: 1441-50. PMID 23775685 DOI: 10.1002/nbm.2972 |
0.42 |
|
2013 |
Dodd MS, Ball V, Bray R, Ashrafian H, Watkins H, Clarke K, Tyler DJ. In vivo mouse cardiac hyperpolarized magnetic resonance spectroscopy. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 15: 19. PMID 23414451 DOI: 10.1186/1532-429X-15-19 |
0.447 |
|
2013 |
Lygate CA, Aksentijevic D, Dawson D, ten Hove M, Phillips D, de Bono JP, Medway DJ, Sebag-Montefiore L, Hunyor I, Channon KM, Clarke K, Zervou S, Watkins H, Balaban RS, Neubauer S. Living without creatine: unchanged exercise capacity and response to chronic myocardial infarction in creatine-deficient mice. Circulation Research. 112: 945-55. PMID 23325497 DOI: 10.1161/Circresaha.112.300725 |
0.624 |
|
2013 |
Schroeder MA, Lau AZ, Chen AP, Gu Y, Nagendran J, Barry J, Hu X, Dyck JR, Tyler DJ, Clarke K, Connelly KA, Wright GA, Cunningham CH. Hyperpolarized (13)C magnetic resonance reveals early- and late-onset changes to in vivo pyruvate metabolism in the failing heart. European Journal of Heart Failure. 15: 130-40. PMID 23258802 DOI: 10.1093/Eurjhf/Hfs192 |
0.348 |
|
2012 |
Lygate CA, Bohl S, ten Hove M, Faller KM, Ostrowski PJ, Zervou S, Medway DJ, Aksentijevic D, Sebag-Montefiore L, Wallis J, Clarke K, Watkins H, Schneider JE, Neubauer S. Moderate elevation of intracellular creatine by targeting the creatine transporter protects mice from acute myocardial infarction. Cardiovascular Research. 96: 466-75. PMID 22915766 DOI: 10.1093/cvr/cvs272 |
0.632 |
|
2012 |
Holloway CJ, Dass S, Suttie JJ, Rider OJ, Cox P, Cochlin LE, Jackson H, Fast AM, Johnson AW, Karamitsos TD, Neubauer S, Clarke K. Exercise training in dilated cardiomyopathy improves rest and stress cardiac function without changes in cardiac high energy phosphate metabolism Heart. 98: 1083-1090. PMID 22739638 DOI: 10.1136/heartjnl-2012-302145 |
0.361 |
|
2012 |
Dodd MS, Ball DR, Schroeder MA, Le Page LM, Atherton HJ, Heather LC, Seymour AM, Ashrafian H, Watkins H, Clarke K, Tyler DJ. In vivo alterations in cardiac metabolism and function in the spontaneously hypertensive rat heart. Cardiovascular Research. 95: 69-76. PMID 22593200 DOI: 10.1093/cvr/cvs164 |
0.388 |
|
2012 |
Heather LC, Cole MA, Tan JJ, Ambrose LJ, Pope S, Abd-Jamil AH, Carter EE, Dodd MS, Yeoh KK, Schofield CJ, Clarke K. Metabolic adaptation to chronic hypoxia in cardiac mitochondria. Basic Research in Cardiology. 107: 268. PMID 22538979 DOI: 10.1007/S00395-012-0268-2 |
0.362 |
|
2012 |
Stuckey DJ, Carr CA, Camelliti P, Tyler DJ, Davies KE, Clarke K. In vivo MRI characterization of progressive cardiac dysfunction in the mdx mouse model of muscular dystrophy. Plos One. 7: e28569. PMID 22235247 DOI: 10.1371/journal.pone.0028569 |
0.363 |
|
2012 |
Evans RD, Clarke K. Myocardial substrate metabolism in heart disease. Frontiers in Bioscience (Scholar Edition). 4: 556-80. PMID 22202077 |
0.41 |
|
2011 |
Carr CA, Stuckey DJ, Tan JJ, Tan SC, Gomes RS, Camelliti P, Messina E, Giacomello A, Ellison GM, Clarke K. Cardiosphere-derived cells improve function in the infarcted rat heart for at least 16 weeks--an MRI study. Plos One. 6: e25669. PMID 22043289 DOI: 10.1371/journal.pone.0025669 |
0.385 |
|
2011 |
Heather LC, Howell NJ, Emmanuel Y, Cole MA, Frenneaux MP, Pagano D, Clarke K. Changes in cardiac substrate transporters and metabolic proteins mirror the metabolic shift in patients with aortic stenosis. Plos One. 6: e26326. PMID 22028857 DOI: 10.1371/journal.pone.0026326 |
0.346 |
|
2011 |
Stuckey DJ, Carr CA, Meader SJ, Tyler DJ, Cole MA, Clarke K. First-pass perfusion CMR two days after infarction predicts severity of functional impairment six weeks later in the rat heart. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 13: 38. PMID 21812990 DOI: 10.1186/1532-429X-13-38 |
0.377 |
|
2011 |
Holloway C, Cochlin L, Codreanu I, Bloch E, Fatemian M, Szmigielski C, Atherton H, Heather L, Francis J, Neubauer S, Robbins P, Montgomery H, Clarke K. Normobaric hypoxia impairs human cardiac energetics. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 3130-5. PMID 21646398 DOI: 10.1096/fj.11-183426 |
0.307 |
|
2011 |
Song W, Dyer E, Stuckey DJ, Copeland O, Leung MC, Bayliss C, Messer A, Wilkinson R, Tremoleda JL, Schneider MD, Harding SE, Redwood CS, Clarke K, Nowak K, Monserrat L, et al. Molecular mechanism of the E99K mutation in cardiac actin (ACTC Gene) that causes apical hypertrophy in man and mouse. The Journal of Biological Chemistry. 286: 27582-93. PMID 21622575 DOI: 10.1074/jbc.M111.252320 |
0.352 |
|
2011 |
Atherton HJ, Dodd MS, Heather LC, Schroeder MA, Griffin JL, Radda GK, Clarke K, Tyler DJ. Role of pyruvate dehydrogenase inhibition in the development of hypertrophy in the hyperthyroid rat heart: a combined magnetic resonance imaging and hyperpolarized magnetic resonance spectroscopy study. Circulation. 123: 2552-61. PMID 21606392 DOI: 10.1161/Circulationaha.110.011387 |
0.421 |
|
2011 |
Cole MA, Murray AJ, Cochlin LE, Heather LC, McAleese S, Knight NS, Sutton E, Jamil AA, Parassol N, Clarke K. A high fat diet increases mitochondrial fatty acid oxidation and uncoupling to decrease efficiency in rat heart. Basic Research in Cardiology. 106: 447-57. PMID 21318295 DOI: 10.1007/s00395-011-0156-1 |
0.393 |
|
2011 |
Crisp A, Yin H, Goyenvalle A, Betts C, Moulton HM, Seow Y, Babbs A, Merritt T, Saleh AF, Gait MJ, Stuckey DJ, Clarke K, Davies KE, Wood MJ. Diaphragm rescue alone prevents heart dysfunction in dystrophic mice. Human Molecular Genetics. 20: 413-21. PMID 21062902 DOI: 10.1093/hmg/ddq477 |
0.407 |
|
2011 |
Holloway CJ, Montgomery HE, Murray AJ, Cochlin LE, Codreanu I, Hopwood N, Johnson AW, Rider OJ, Levett DZ, Tyler DJ, Francis JM, Neubauer S, Grocott MP, Clarke K. Cardiac response to hypobaric hypoxia: persistent changes in cardiac mass, function, and energy metabolism after a trek to Mt. Everest Base Camp. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 792-6. PMID 20978235 DOI: 10.1096/fj.10-172999 |
0.389 |
|
2010 |
Desrois M, Clarke K, Lan C, Dalmasso C, Cole M, Portha B, Cozzone PJ, Bernard M. Upregulation of eNOS and unchanged energy metabolism in increased susceptibility of the aging type 2 diabetic GK rat heart to ischemic injury. American Journal of Physiology. Heart and Circulatory Physiology. 299: H1679-86. PMID 20729402 DOI: 10.1152/ajpheart.00998.2009 |
0.418 |
|
2010 |
Berman M, Ali A, Ashley E, Freed D, Clarke K, Tsui S, Parameshwar J, Large S. Is stress cardiomyopathy the underlying cause of ventricular dysfunction associated with brain death? The Journal of Heart and Lung Transplantation : the Official Publication of the International Society For Heart Transplantation. 29: 957-65. PMID 20627624 DOI: 10.1016/J.Healun.2010.04.008 |
0.386 |
|
2010 |
Fischer A, Ten Hove M, Sebag-Montefiore L, Wagner H, Clarke K, Watkins H, Lygate CA, Neubauer S. Changes in creatine transporter function during cardiac maturation in the rat. Bmc Developmental Biology. 10: 70. PMID 20569423 DOI: 10.1186/1471-213X-10-70 |
0.315 |
|
2010 |
Stuckey DJ, Ishii H, Chen QZ, Boccaccini AR, Hansen U, Carr CA, Roether JA, Jawad H, Tyler DJ, Ali NN, Clarke K, Harding SE. Magnetic resonance imaging evaluation of remodeling by cardiac elastomeric tissue scaffold biomaterials in a rat model of myocardial infarction. Tissue Engineering. Part A. 16: 3395-402. PMID 20528670 DOI: 10.1089/ten.TEA.2010.0213 |
0.369 |
|
2010 |
Heather LC, Cole MA, Atherton HJ, Coumans WA, Evans RD, Tyler DJ, Glatz JF, Luiken JJ, Clarke K. Adenosine monophosphate-activated protein kinase activation, substrate transporter translocation, and metabolism in the contracting hyperthyroid rat heart. Endocrinology. 151: 422-31. PMID 19940039 DOI: 10.1210/en.2009-0593 |
0.396 |
|
2010 |
Phillips D, Ten Hove M, Schneider JE, Wu CO, Sebag-Montefiore L, Aponte AM, Lygate CA, Wallis J, Clarke K, Watkins H, Balaban RS, Neubauer S. Mice over-expressing the myocardial creatine transporter develop progressive heart failure and show decreased glycolytic capacity. Journal of Molecular and Cellular Cardiology. 48: 582-90. PMID 19913546 DOI: 10.1016/J.Yjmcc.2009.10.033 |
0.483 |
|
2010 |
Heather LC, Carr CA, Stuckey DJ, Pope S, Morten KJ, Carter EE, Edwards LM, Clarke K. Critical role of complex III in the early metabolic changes following myocardial infarction. Cardiovascular Research. 85: 127-36. PMID 19666902 DOI: 10.1093/cvr/cvp276 |
0.381 |
|
2009 |
Hudsmith LE, Tyler DJ, Emmanuel Y, Petersen SE, Francis JM, Watkins H, Clarke K, Robson MD, Neubauer S. (31)P cardiac magnetic resonance spectroscopy during leg exercise at 3 Tesla. The International Journal of Cardiovascular Imaging. 25: 819-26. PMID 19697152 DOI: 10.1007/s10554-009-9492-8 |
0.305 |
|
2009 |
Schroeder MA, Atherton HJ, Ball DR, Cole MA, Heather LC, Griffin JL, Clarke K, Radda GK, Tyler DJ. Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2529-38. PMID 19329759 DOI: 10.1096/Fj.09-129171 |
0.358 |
|
2008 |
Zhang W, ten Hove M, Schneider JE, Stuckey DJ, Sebag-Montefiore L, Bia BL, Radda GK, Davies KE, Neubauer S, Clarke K. Abnormal cardiac morphology, function and energy metabolism in the dystrophic mdx mouse: an MRI and MRS study. Journal of Molecular and Cellular Cardiology. 45: 754-60. PMID 18929569 DOI: 10.1016/J.Yjmcc.2008.09.125 |
0.462 |
|
2008 |
Stuckey DJ, Carr CA, Tyler DJ, Aasum E, Clarke K. Novel MRI method to detect altered left ventricular ejection and filling patterns in rodent models of disease. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 60: 582-7. PMID 18727095 DOI: 10.1002/mrm.21677 |
0.304 |
|
2008 |
Gulston MK, Rubtsov DV, Atherton HJ, Clarke K, Davies KE, Lilley KS, Griffin JL. A combined metabolomic and proteomic investigation of the effects of a failure to express dystrophin in the mouse heart. Journal of Proteome Research. 7: 2069-77. PMID 18386883 DOI: 10.1021/pr800070p |
0.397 |
|
2008 |
Murray AJ, Cole MA, Lygate CA, Carr CA, Stuckey DJ, Little SE, Neubauer S, Clarke K. Increased mitochondrial uncoupling proteins, respiratory uncoupling and decreased efficiency in the chronically infarcted rat heart. Journal of Molecular and Cellular Cardiology. 44: 694-700. PMID 18328500 DOI: 10.1016/j.yjmcc.2008.01.008 |
0.486 |
|
2007 |
Murray AJ, Edwards LM, Clarke K. Mitochondria and heart failure. Current Opinion in Clinical Nutrition and Metabolic Care. 10: 704-11. PMID 18089951 DOI: 10.1097/MCO.0b013e3282f0ecbe |
0.402 |
|
2007 |
Panagia M, Schneider JE, Brown B, Cole MA, Clarke K. Abnormal function and glucose metabolism in the type-2 diabetic db/db mouse heart. Canadian Journal of Physiology and Pharmacology. 85: 289-94. PMID 17612636 DOI: 10.1139/y07-028 |
0.409 |
|
2006 |
Abozguia K, Clarke K, Lee L, Frenneaux M. Modification of myocardial substrate use as a therapy for heart failure. Nature Clinical Practice. Cardiovascular Medicine. 3: 490-8. PMID 16932766 DOI: 10.1038/ncpcardio0583 |
0.427 |
|
2006 |
Tyler DJ, Lygate CA, Schneider JE, Cassidy PJ, Neubauer S, Clarke K. CINE-MR imaging of the normal and infarcted rat heart using an 11.7 T vertical bore MR system. Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society For Cardiovascular Magnetic Resonance. 8: 327-33. PMID 16669175 DOI: 10.1080/10976640500451903 |
0.318 |
|
2006 |
Murray AJ, Lygate CA, Cole MA, Carr CA, Radda GK, Neubauer S, Clarke K. Insulin resistance, abnormal energy metabolism and increased ischemic damage in the chronically infarcted rat heart. Cardiovascular Research. 71: 149-57. PMID 16616054 DOI: 10.1016/J.Cardiores.2006.02.031 |
0.42 |
|
2006 |
Wilding JR, Lygate CA, Davies KE, Neubauer S, Clarke K. MLP accumulation and remodelling in the infarcted rat heart. European Journal of Heart Failure. 8: 343-6. PMID 16330255 DOI: 10.1016/j.ejheart.2005.10.006 |
0.365 |
|
2005 |
Murray AJ, Panagia M, Hauton D, Gibbons GF, Clarke K. Plasma free fatty acids and peroxisome proliferator-activated receptor alpha in the control of myocardial uncoupling protein levels. Diabetes. 54: 3496-502. PMID 16306367 |
0.374 |
|
2005 |
Lee L, Campbell R, Scheuermann-Freestone M, Taylor R, Gunaruwan P, Williams L, Ashrafian H, Horowitz J, Fraser AG, Clarke K, Frenneaux M. Metabolic modulation with perhexiline in chronic heart failure: a randomized, controlled trial of short-term use of a novel treatment. Circulation. 112: 3280-8. PMID 16301359 DOI: 10.1161/CIRCULATIONAHA.105.551457 |
0.378 |
|
2005 |
Wallis J, Lygate CA, Fischer A, ten Hove M, Schneider JE, Sebag-Montefiore L, Dawson D, Hulbert K, Zhang W, Zhang MH, Watkins H, Clarke K, Neubauer S. Supranormal myocardial creatine and phosphocreatine concentrations lead to cardiac hypertrophy and heart failure: insights from creatine transporter-overexpressing transgenic mice. Circulation. 112: 3131-9. PMID 16286605 DOI: 10.1161/CIRCULATIONAHA.105.572990 |
0.505 |
|
2005 |
ten Hove M, Lygate CA, Fischer A, Schneider JE, Sang AE, Hulbert K, Sebag-Montefiore L, Watkins H, Clarke K, Isbrandt D, Wallis J, Neubauer S. Reduced inotropic reserve and increased susceptibility to cardiac ischemia/reperfusion injury in phosphocreatine-deficient guanidinoacetate-N-methyltransferase-knockout mice. Circulation. 111: 2477-85. PMID 15883212 DOI: 10.1161/01.CIR.0000165147.99592.01 |
0.415 |
|
2005 |
Panagia M, Gibbons GF, Radda GK, Clarke K. PPAR-alpha activation required for decreased glucose uptake and increased susceptibility to injury during ischemia. American Journal of Physiology. Heart and Circulatory Physiology. 288: H2677-83. PMID 15665064 DOI: 10.1152/Ajpheart.00200.2004 |
0.376 |
|
2005 |
Wilding JR, Schneider JE, Sang AE, Davies KE, Neubauer S, Clarke K. Dystrophin- and MLP-deficient mouse hearts: marked differences in morphology and function, but similar accumulation of cytoskeletal proteins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 79-81. PMID 15494447 DOI: 10.1096/fj.04-1731fje |
0.456 |
|
2004 |
Schneider JE, Böse J, Bamforth SD, Gruber AD, Broadbent C, Clarke K, Neubauer S, Lengeling A, Bhattacharya S. Identification of cardiac malformations in mice lacking Ptdsr using a novel high-throughput magnetic resonance imaging technique. Bmc Developmental Biology. 4: 16. PMID 15615595 DOI: 10.1186/1471-213X-4-16 |
0.348 |
|
2004 |
Murray AJ, Anderson RE, Watson GC, Radda GK, Clarke K. Uncoupling proteins in human heart. Lancet (London, England). 364: 1786-8. PMID 15541452 DOI: 10.1016/S0140-6736(04)17402-3 |
0.375 |
|
2004 |
Schneider JE, Hulbert KJ, Lygate CA, Ten Hove M, Cassidy PJ, Clarke K, Neubauer S. Long-term stability of cardiac function in normal and chronically failing mouse hearts in a vertical-bore MR system. Magma (New York, N.Y.). 17: 162-9. PMID 15538660 DOI: 10.1007/s10334-004-0056-6 |
0.407 |
|
2004 |
Schneider JE, Tyler DJ, ten Hove M, Sang AE, Cassidy PJ, Fischer A, Wallis J, Sebag-Montefiore LM, Watkins H, Isbrandt D, Clarke K, Neubauer S. In vivo cardiac 1H-MRS in the mouse. Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine. 52: 1029-35. PMID 15508174 DOI: 10.1002/mrm.20257 |
0.415 |
|
2004 |
Bamforth SD, Bragança J, Farthing CR, Schneider JE, Broadbent C, Michell AC, Clarke K, Neubauer S, Norris D, Brown NA, Anderson RH, Bhattacharya S. Cited2 controls left-right patterning and heart development through a Nodal-Pitx2c pathway. Nature Genetics. 36: 1189-96. PMID 15475956 DOI: 10.1038/Ng1446 |
0.306 |
|
2004 |
Desrois M, Sidell RJ, Gauguier D, Davey CL, Radda GK, Clarke K. Gender differences in hypertrophy, insulin resistance and ischemic injury in the aging type 2 diabetic rat heart. Journal of Molecular and Cellular Cardiology. 37: 547-55. PMID 15276024 DOI: 10.1016/J.Yjmcc.2004.05.014 |
0.337 |
|
2003 |
Scheuermann-Freestone M, Madsen PL, Manners D, Blamire AM, Buckingham RE, Styles P, Radda GK, Neubauer S, Clarke K. Abnormal cardiac and skeletal muscle energy metabolism in patients with type 2 diabetes. Circulation. 107: 3040-6. PMID 12810608 DOI: 10.1161/01.Cir.0000072789.89096.10 |
0.322 |
|
2003 |
Lygate CA, Hulbert K, Monfared M, Cole MA, Clarke K, Neubauer S. The PPARgamma-activator rosiglitazone does not alter remodeling but increases mortality in rats post-myocardial infarction. Cardiovascular Research. 58: 632-7. PMID 12798436 DOI: 10.1016/S0008-6363(03)00289-X |
0.407 |
|
2003 |
Mielke M, Paterson DJ, Sang AE, Radda GK, Clarke K. The mechanism underlying the positive inotropic effect of angiotensin II in the isolated perfused rabbit heart: a 31P NMR study. The International Journal of Biochemistry & Cell Biology. 35: 984-91. PMID 12676182 DOI: 10.1016/S1357-2725(02)00304-7 |
0.309 |
|
2002 |
Sidell RJ, Cole MA, Draper NJ, Desrois M, Buckingham RE, Clarke K. Thiazolidinedione treatment normalizes insulin resistance and ischemic injury in the zucker Fatty rat heart. Diabetes. 51: 1110-7. PMID 11916933 |
0.31 |
|
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