| Year |
Citation |
Score |
| 2019 |
Chapman EM, Lant B, Ohashi Y, Yu B, Schertzberg M, Go C, Dogra D, Koskimäki J, Girard R, Li Y, Fraser AG, Awad IA, Abdelilah-Seyfried S, Gingras AC, Derry WB. A conserved CCM complex promotes apoptosis non-autonomously by regulating zinc homeostasis. Nature Communications. 10: 1791. PMID 30996251 DOI: 10.1038/S41467-019-09829-Z |
0.301 |
|
| 2017 |
Tan JH, Fraser AG. The combinatorial control of alternative splicing in C. elegans. Plos Genetics. 13: e1007033. PMID 29121637 DOI: 10.1371/Journal.Pgen.1007033 |
0.373 |
|
| 2017 |
Verster AJ, Styles EB, Mateo A, Derry BW, Andrews BJ, Fraser AG. Taxonomically Restricted Genes with Essential Functions Frequently Play Roles in Chromosome Segregation in Caenorhabditis elegans and Saccharomyces cerevisiae. G3 (Bethesda, Md.). PMID 28839119 DOI: 10.1534/G3.117.300193 |
0.445 |
|
| 2017 |
Johnston WL, Krizus A, Ramani AK, Dunham W, Youn JY, Fraser AG, Gingras AC, Dennis JW. C. elegans SUP-46, an HNRNPM family RNA-binding protein that prevents paternally-mediated epigenetic sterility. Bmc Biology. 15: 61. PMID 28716093 DOI: 10.1186/S12915-017-0398-Y |
0.312 |
|
| 2015 |
Fraser A. Essential Human Genes. Cell Systems. 1: 381-2. PMID 27136352 DOI: 10.1016/j.cels.2015.12.007 |
0.331 |
|
| 2015 |
Vu V, Verster AJ, Schertzberg M, Chuluunbaatar T, Spensley M, Pajkic D, Hart GT, Moffat J, Fraser AG. Natural Variation in Gene Expression Modulates the Severity of Mutant Phenotypes. Cell. 162: 391-402. PMID 26186192 DOI: 10.1016/J.Cell.2015.06.037 |
0.427 |
|
| 2015 |
Fraser A. Essential Human Genes Cell Systems. 1: 381-382. DOI: 10.1016/J.Cels.2015.12.007 |
0.435 |
|
| 2014 |
Norris AD, Gao S, Norris ML, Ray D, Ramani AK, Fraser AG, Morris Q, Hughes TR, Zhen M, Calarco JA. A pair of RNA-binding proteins controls networks of splicing events contributing to specialization of neural cell types. Molecular Cell. 54: 946-59. PMID 24910101 DOI: 10.1016/J.Molcel.2014.05.004 |
0.316 |
|
| 2014 |
Parts L, Liu YC, Tekkedil MM, Steinmetz LM, Caudy AA, Fraser AG, Boone C, Andrews BJ, Rosebrock AP. Heritability and genetic basis of protein level variation in an outbred population. Genome Research. 24: 1363-70. PMID 24823668 DOI: 10.1101/Gr.170506.113 |
0.357 |
|
| 2014 |
Verster AJ, Ramani AK, McKay SJ, Fraser AG. Comparative RNAi screens in C. elegans and C. briggsae reveal the impact of developmental system drift on gene function. Plos Genetics. 10: e1004077. PMID 24516395 DOI: 10.1371/Journal.Pgen.1004077 |
0.453 |
|
| 2013 |
Ray D, Kazan H, Cook KB, Weirauch MT, Najafabadi HS, Li X, Gueroussov S, Albu M, Zheng H, Yang A, Na H, Irimia M, Matzat LH, Dale RK, Smith SA, ... ... Fraser AG, et al. A compendium of RNA-binding motifs for decoding gene regulation. Nature. 499: 172-7. PMID 23846655 DOI: 10.1038/Nature12311 |
0.347 |
|
| 2013 |
Fraser A, Lehner B. Systems Biology of Caenorhabditis elegans Handbook of Systems Biology. 367-390. DOI: 10.1016/B978-0-12-385944-0.00019-8 |
0.425 |
|
| 2012 |
Wilson CH, Crombie C, van der Weyden L, Poulogiannis G, Rust AG, Pardo M, Gracia T, Yu L, Choudhary J, Poulin GB, McIntyre RE, Winton DJ, March HN, Arends MJ, Fraser AG, et al. Nuclear receptor binding protein 1 regulates intestinal progenitor cell homeostasis and tumour formation. The Embo Journal. 31: 2486-97. PMID 22510880 DOI: 10.1038/Emboj.2012.91 |
0.352 |
|
| 2012 |
Ramani AK, Chuluunbaatar T, Verster AJ, Na H, Vu V, Pelte N, Wannissorn N, Jiao A, Fraser AG. The majority of animal genes are required for wild-type fitness. Cell. 148: 792-802. PMID 22341449 DOI: 10.1016/J.Cell.2012.01.019 |
0.462 |
|
| 2012 |
Trachtenberg AJ, Robert JH, Abdalla AE, Fraser A, He SY, Lacy JN, Rivas-Morello C, Truong A, Hardiman G, Ohno-Machado L, Liu F, Hovig E, Kuo WP. A primer on the current state of microarray technologies. Methods in Molecular Biology (Clifton, N.J.). 802: 3-17. PMID 22130870 DOI: 10.1007/978-1-61779-400-1_1 |
0.319 |
|
| 2011 |
Ramani AK, Calarco JA, Pan Q, Mavandadi S, Wang Y, Nelson AC, Lee LJ, Morris Q, Blencowe BJ, Zhen M, Fraser AG. Genome-wide analysis of alternative splicing in Caenorhabditis elegans. Genome Research. 21: 342-8. PMID 21177968 DOI: 10.1101/Gr.114645.110 |
0.374 |
|
| 2011 |
Ip JY, Schmidt D, Pan Q, Ramani AK, Fraser AG, Odom DT, Blencowe BJ. Global impact of RNA polymerase II elongation inhibition on alternative splicing regulation. Genome Research. 21: 390-401. PMID 21163941 DOI: 10.1101/Gr.111070.110 |
0.313 |
|
| 2010 |
Lee I, Lehner B, Vavouri T, Shin J, Fraser AG, Marcotte EM. Predicting genetic modifier loci using functional gene networks. Genome Research. 20: 1143-53. PMID 20538624 DOI: 10.1101/Gr.102749.109 |
0.732 |
|
| 2010 |
Sudbery I, Enright AJ, Fraser AG, Dunham I. Systematic analysis of off-target effects in an RNAi screen reveals microRNAs affecting sensitivity to TRAIL-induced apoptosis. Bmc Genomics. 11: 175. PMID 20230625 DOI: 10.1186/1471-2164-11-175 |
0.349 |
|
| 2008 |
Tischler J, Lehner B, Fraser AG. Evolutionary plasticity of genetic interaction networks. Nature Genetics. 40: 390-1. PMID 18362882 DOI: 10.1038/Ng.114 |
0.591 |
|
| 2008 |
Lee I, Lehner B, Crombie C, Wong W, Fraser AG, Marcotte EM. A single gene network accurately predicts phenotypic effects of gene perturbation in Caenorhabditis elegans. Nature Genetics. 40: 181-8. PMID 18223650 DOI: 10.1038/Ng.2007.70 |
0.609 |
|
| 2006 |
Lehner B, Tischler J, Fraser AG. RNAi screens in Caenorhabditis elegans in a 96-well liquid format and their application to the systematic identification of genetic interactions. Nature Protocols. 1: 1617-20. PMID 17406454 DOI: 10.1038/Nprot.2006.245 |
0.614 |
|
| 2006 |
Tischler J, Lehner B, Chen N, Fraser AG. Combinatorial RNA interference in Caenorhabditis elegans reveals that redundancy between gene duplicates can be maintained for more than 80 million years of evolution. Genome Biology. 7: R69. PMID 16884526 DOI: 10.1186/Gb-2006-7-8-R69 |
0.655 |
|
| 2006 |
Lehner B, Crombie C, Tischler J, Fortunato A, Fraser AG. Systematic mapping of genetic interactions in Caenorhabditis elegans identifies common modifiers of diverse signaling pathways. Nature Genetics. 38: 896-903. PMID 16845399 DOI: 10.1038/Ng1844 |
0.641 |
|
| 2006 |
Lehner B, Calixto A, Crombie C, Tischler J, Fortunato A, Chalfie M, Fraser AG. Loss of LIN-35, the Caenorhabditis elegans ortholog of the tumor suppressor p105Rb, results in enhanced RNA interference. Genome Biology. 7: R4. PMID 16507136 DOI: 10.1186/Gb-2006-7-1-R4 |
0.625 |
|
| 2005 |
Fortunato A, Fraser AG. Uncover genetic interactions in Caenorhabditis elegans by RNA interference. Bioscience Reports. 25: 299-307. PMID 16307378 DOI: 10.1007/S10540-005-2892-7 |
0.467 |
|
| 2005 |
Lehner B, Tischler J, Fraser AG. Systems biology: where it's at in 2005. Genome Biology. 6: 338. PMID 16086862 DOI: 10.1186/Gb-2005-6-8-338 |
0.475 |
|
| 2005 |
Poulin G, Dong Y, Fraser AG, Hopper NA, Ahringer J. Chromatin regulation and sumoylation in the inhibition of Ras-induced vulval development in Caenorhabditis elegans. The Embo Journal. 24: 2613-23. PMID 15990876 DOI: 10.1038/Sj.Emboj.7600726 |
0.318 |
|
| 2005 |
Crombie C, Fraser A. Treating genetic disease through RNA interference Lancet. 365: 1288-1290. PMID 15823365 DOI: 10.1016/S0140-6736(05)61006-9 |
0.323 |
|
| 2004 |
Lehner B, Fraser AG. 5,000 RNAi experiments on a chip. Nature Methods. 1: 103-4. PMID 15782169 DOI: 10.1038/Nmeth1104-103 |
0.585 |
|
| 2004 |
Fraser A. Towards full employment: Using RNAi to find roles for the redundant Oncogene. 23: 8346-8352. PMID 15517015 DOI: 10.1038/Sj.Onc.1208044 |
0.46 |
|
| 2004 |
Lehner B, Fraser AG. Protein domains enriched in mammalian tissue-specific or widely expressed genes. Trends in Genetics : Tig. 20: 468-72. PMID 15363898 DOI: 10.1016/J.Tig.2004.08.002 |
0.554 |
|
| 2004 |
Lehner B, Fraser AG. A first-draft human protein-interaction map. Genome Biology. 5: R63. PMID 15345047 DOI: 10.1186/Gb-2004-5-9-R63 |
0.565 |
|
| 2004 |
Lettre G, Kritikou EA, Jaeggi M, Calixto A, Fraser AG, Kamath RS, Ahringer J, Hengartner MO. Genome-wide RNAi identifies p53-dependent and -independent regulators of germ cell apoptosis in C. elegans. Cell Death and Differentiation. 11: 1198-203. PMID 15272318 DOI: 10.1038/Sj.Cdd.4401488 |
0.42 |
|
| 2004 |
Fraser AG, Marcotte EM. Development through the eyes of functional genomics. Current Opinion in Genetics & Development. 14: 336-42. PMID 15261648 DOI: 10.1016/J.Gde.2004.06.015 |
0.439 |
|
| 2004 |
Fraser AG, Marcotte EM. A probabilistic view of gene function. Nature Genetics. 36: 559-64. PMID 15167932 DOI: 10.1038/Ng1370 |
0.437 |
|
| 2004 |
Lehner B, Fraser AG, Sanderson CM. Technique review: how to use RNA interference. Briefings in Functional Genomics & Proteomics. 3: 68-83. PMID 15163361 DOI: 10.1093/Bfgp/3.1.68 |
0.571 |
|
| 2004 |
Fraser A. Human genes hit the big screen Nature. 428: 375-378. PMID 15042071 DOI: 10.1038/428375A |
0.417 |
|
| 2004 |
Li S, Armstrong CM, Bertin N, Ge H, Milstein S, Boxem M, Vidalain PO, Han JD, Chesneau A, Hao T, Goldberg DS, Li N, Martinez M, Rual JF, Lamesch P, ... ... Fraser A, et al. A map of the interactome network of the metazoan C. elegans. Science (New York, N.Y.). 303: 540-3. PMID 14704431 DOI: 10.1126/Science.1091403 |
0.341 |
|
| 2003 |
Simmer F, Moorman C, van der Linden AM, Kuijk E, van den Berghe PV, Kamath RS, Fraser AG, Ahringer J, Plasterk RH. Genome-wide RNAi of C. elegans using the hypersensitive rrf-3 strain reveals novel gene functions. Plos Biology. 1: E12. PMID 14551910 DOI: 10.1371/Journal.Pbio.0000012 |
0.468 |
|
| 2003 |
Vastenhouw NL, Fischer SE, Robert VJ, Thijssen KL, Fraser AG, Kamath RS, Ahringer J, Plasterk RH. A genome-wide screen identifies 27 genes involved in transposon silencing in C. elegans. Current Biology : Cb. 13: 1311-6. PMID 12906791 DOI: 10.1016/S0960-9822(03)00539-6 |
0.445 |
|
| 2003 |
Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, Ahringer J, Li H, Kenyon C. Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature. 424: 277-83. PMID 12845331 DOI: 10.1038/Nature01789 |
0.333 |
|
| 2003 |
Pothof J, van Haaften G, Thijssen K, Kamath RS, Fraser AG, Ahringer J, Plasterk RH, Tijsterman M. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Genes & Development. 17: 443-8. PMID 12600937 DOI: 10.1101/Gad.1060703 |
0.433 |
|
| 2003 |
Ashrafi K, Chang FY, Watts JL, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature. 421: 268-72. PMID 12529643 DOI: 10.1038/Nature01279 |
0.378 |
|
| 2003 |
Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, Gotta M, Kanapin A, Le Bot N, Moreno S, Sohrmann M, Welchman DP, Zipperlen P, Ahringer J. Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature. 421: 231-7. PMID 12529635 DOI: 10.1038/Nature01278 |
0.465 |
|
| 2003 |
Lee SS, Lee RY, Fraser AG, Kamath RS, Ahringer J, Ruvkun G. A systematic RNAi screen identifies a critical role for mitochondria in C. elegans longevity. Nature Genetics. 33: 40-8. PMID 12447374 DOI: 10.1038/Ng1056 |
0.409 |
|
| 2002 |
Bentley SD, Chater KF, Cerdeño-Tárraga AM, Challis GL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen CW, Collins M, ... ... Fraser A, et al. Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature. 417: 141-7. PMID 12000953 DOI: 10.1038/417141A |
0.375 |
|
| 2002 |
Wood V, Gwilliam R, Rajandream MA, Lyne M, Lyne R, Stewart A, Sgouros J, Peat N, Hayles J, Baker S, Basham D, Bowman S, Brooks K, Brown D, Brown S, ... ... Fraser A, et al. The genome sequence of Schizosaccharomyces pombe. Nature. 415: 871-80. PMID 11859360 DOI: 10.1038/Nature724 |
0.448 |
|
| 2001 |
Zipperlen P, Fraser AG, Kamath RS, Martinez-Campos M, Ahringer J. Roles for 147 embryonic lethal genes on C.elegans chromosome I identified by RNA interference and video microscopy. The Embo Journal. 20: 3984-92. PMID 11483502 DOI: 10.1093/Emboj/20.15.3984 |
0.465 |
|
| 2001 |
Kamath RS, Martinez-Campos M, Zipperlen P, Fraser AG, Ahringer J. Effectiveness of specific RNA-mediated interference through ingested double-stranded RNA in Caenorhabditis elegans. Genome Biology. 2: RESEARCH0002. PMID 11178279 DOI: 10.1186/Gb-2000-2-1-Research0002 |
0.358 |
|
| 2000 |
Fraser AG, Kamath RS, Zipperlen P, Martinez-Campos M, Sohrmann M, Ahringer J. Functional genomic analysis of C. elegans chromosome I by systematic RNA interference. Nature. 408: 325-30. PMID 11099033 DOI: 10.1038/35042517 |
0.481 |
|
| 1997 |
James C, Gschmeissner S, Fraser A, Evan GI. CED-4 induces chromatin condensation in Schizosaccharomyces pombe and is inhibited by direct physical association with CED-9 Current Biology. 7: 246-252. PMID 9094313 DOI: 10.1016/S0960-9822(06)00120-5 |
0.376 |
|
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