Eng-Ang Ling, Ph.D. D.Sc. - Publications

Affiliations: 
1972-1025 Anatomy National University of Singapore, Singapore, Singapore 
Area:
Microglia

157 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Yao YY, Ling EA, Lu D. Microglia mediated neuroinflammation - signaling regulation and therapeutic considerations with special reference to some natural compounds. Histology and Histopathology. 18239. PMID 32662061 DOI: 10.14670/Hh-18-239  0.385
2019 Yuan Y, Wu C, Ling EA. Heterogeneity of Microglia Phenotypes: Developmental, Functional and Some Therapeutic Considerations. Current Pharmaceutical Design. 25: 2375-2393. PMID 31584369 DOI: 10.2174/1381612825666190722114248  0.34
2018 Gupta N, Shyamasundar S, Patnala R, Karthikeyan A, Arumugam TV, Ling EA, Dheen ST. Recent progress in therapeutic strategies for microglia-mediated neuroinflammation in neuropathologies. Expert Opinion On Therapeutic Targets. PMID 30138572 DOI: 10.1080/14728222.2018.1515917  0.356
2018 Singh DK, Ling EA, Kaur C. Hypoxia and myelination deficits in the developing brain. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. PMID 29964158 DOI: 10.1016/J.Ijdevneu.2018.06.012  0.389
2018 Rathnasamy G, Fould WS, Ling EA, Kaur C. Retinal Microglia - a Key Player in Healthy and Diseased Retina. Progress in Neurobiology. PMID 29864456 DOI: 10.1016/J.Pneurobio.2018.05.006  0.574
2018 Karthikeyan A, Gupta N, Tang C, Mallilankaraman K, Silambarasan M, Shi M, Lu L, Ang BT, Ling EA, Dheen ST. Microglial SMAD4 regulated by microRNA-146a promotes migration of microglia which support tumor progression in a glioma environment. Oncotarget. 9: 24950-24969. PMID 29861845 DOI: 10.18632/Oncotarget.25116  0.34
2018 Li JJ, Liu SJ, Liu XY, Ling EA. Herbal compounds with special reference to gastrodin as potential therapeutic agents for microglia mediated neuroinflammation. Current Medicinal Chemistry. PMID 29446722 DOI: 10.2174/0929867325666180214123929  0.339
2017 Cao Q, Karthikeyan A, Dheen ST, Kaur C, Ling EA. Production of proinflammatory mediators in activated microglia is synergistically regulated by Notch-1, glycogen synthase kinase (GSK-3β) and NF-κB/p65 signalling. Plos One. 12: e0186764. PMID 29049420 DOI: 10.1371/Journal.Pone.0186764  0.568
2017 Kaur C, Rathnasamy G, Ling EA. Biology of Microglia in the Developing Brain. Journal of Neuropathology and Experimental Neurology. 76: 736-753. PMID 28859332 DOI: 10.1093/Jnen/Nlx056  0.623
2017 Kaur C, Ling EA. The circumventricular organs. Histology and Histopathology. 11881. PMID 28177105 DOI: 10.14670/Hh-11-881  0.488
2016 Wu CY, Fang M, Karthikeyan A, Yuan Y, Ling EA. Scutellarin as a therapeutic agent in microglia-mediated neuroinflammation in cerebral ischemia. Current Medicinal Chemistry. PMID 27855618 DOI: 10.2174/0929867324666161118142045  0.438
2016 Yang XH, Ding Y, Li W, Zhang RY, Wu JL, Ling EA, Wu W, Zeng YS. Effects of electroacupuncture and the retinoid X receptor (RXR) signalling pathway on oligodendrocyte differentiation in the demyelinated spinal cord of rats. Acupuncture in Medicine : Journal of the British Medical Acupuncture Society. PMID 27841975 DOI: 10.1136/Acupmed-2016-011134  0.312
2016 Yao L, Lu P, Ling EA. Melatonin Suppresses Toll Like Receptor 4-Dependent Caspase-3 Signaling Activation Coupled with Reduced Production of Proinflammatory Mediators in Hypoxic Microglia. Plos One. 11: e0166010. PMID 27812200 DOI: 10.1371/Journal.Pone.0166010  0.439
2016 Kaur C, Ling EA. Transitory cystic cavities in the developing mammalian brain - normal or anomalous? Journal of Anatomy. PMID 27761896 DOI: 10.1111/Joa.12556  0.529
2016 Rathnasamy G, Foulds WS, Ling EA, Kaur C. Glutamate Inhibits the Pro-Survival Effects of Insulin-Like Growth Factor-1 on Retinal Ganglion Cells in Hypoxic Neonatal Rat Retina. Molecular Neurobiology. PMID 27180072 DOI: 10.1007/S12035-016-9905-3  0.524
2016 Fang M, Yuan Y, Lu J, Li HE, Zhao M, Ling EA, Wu CY. Scutellarin promotes microglia-mediated astrogliosis coupled with improved behavioral function in cerebral ischemia. Neurochemistry International. PMID 27105682 DOI: 10.1016/J.Neuint.2016.04.007  0.41
2016 Yuan Y, Fang M, Wu CY, Ling EA. Scutellarin as a Potential Therapeutic Agent for Microglia-Mediated Neuroinflammation in Cerebral Ischemia. Neuromolecular Medicine. PMID 27103430 DOI: 10.1007/S12017-016-8394-X  0.392
2016 Zeng X, Ma YH, Chen YF, Qiu XC, Wu JL, Ling EA, Zeng YS. Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury. Journal of Biomedical Materials Research. Part A. PMID 26991461 DOI: 10.1002/Jbm.A.35720  0.341
2016 Kaur C, Rathnasamy G, Ling EA. The Choroid Plexus in Healthy and Diseased Brain. Journal of Neuropathology and Experimental Neurology. PMID 26888305 DOI: 10.1093/Jnen/Nlv030  0.604
2016 Lin XY, Lai BQ, Zeng X, Che MT, Ling EA, Wu W, Zeng YS. Cell Transplantation and Neuroengineering Approach for Spinal Cord Injury Treatment: A Summary of Current Laboratory Findings and Review of Literature. Cell Transplantation. PMID 26850705 DOI: 10.3727/096368916X690836  0.306
2015 Li G, Che MT, Zhang K, Qin LN, Zhang YT, Chen RQ, Rong LM, Liu S, Ding Y, Shen HY, Long SM, Wu JL, Ling EA, Zeng YS. Graft of the NT-3 persistent delivery gelatin sponge scaffold promotes axon regeneration, attenuates inflammation, and induces cell migration in rat and canine with spinal cord injury. Biomaterials. 83: 233-248. PMID 26774562 DOI: 10.1016/J.Biomaterials.2015.11.059  0.34
2015 Fang M, Yuan Y, Rangarajan P, Lu J, Wu Y, Wang H, Wu C, Ling EA. Scutellarin regulates microglia-mediated TNC1 astrocytic reaction and astrogliosis in cerebral ischemia in the adult rats. Bmc Neuroscience. 16: 84. PMID 26608466 DOI: 10.1186/S12868-015-0219-6  0.431
2015 Rangarajan P, Karthikeyan A, Lu J, Ling EA, Thameem Dheen S. Sirtuin 3 regulates Foxo3a-mediated antioxidant pathway in microglia. Neuroscience. PMID 26523980 DOI: 10.1016/j.neuroscience.2015.10.048  0.342
2015 Rathnasamy G, Murugan M, Ling EA, Kaur C. Hypoxia-Induced Iron Accumulation in Oligodendrocytes Mediates Apoptosis by Eliciting Endoplasmic Reticulum Stress. Molecular Neurobiology. PMID 26319559 DOI: 10.1007/S12035-015-9389-6  0.68
2015 Zeng X, Qiu XC, Ma YH, Duan JJ, Chen YF, Gu HY, Wang JM, Ling EA, Wu JL, Wu W, Zeng YS. Integration of donor mesenchymal stem cell-derived neuron-like cells into host neural network after rat spinal cord transection. Biomaterials. 53: 184-201. PMID 25890718 DOI: 10.1016/J.Biomaterials.2015.02.073  0.331
2015 Ding Y, Zhang RY, He B, Liu Z, Zhang K, Ruan JW, Ling EA, Wu JL, Zeng YS. Combination of electroacupuncture and grafted mesenchymal stem cells overexpressing TrkC improves remyelination and function in demyelinated spinal cord of rats. Scientific Reports. 5: 9133. PMID 25779025 DOI: 10.1038/Srep09133  0.309
2015 Yuan Y, Rangarajan P, Kan EM, Wu Y, Wu C, Ling EA. Scutellarin regulates the Notch pathway and affects the migration and morphological transformation of activated microglia in experimentally induced cerebral ischemia in rats and in activated BV-2 microglia. Journal of Neuroinflammation. 12: 11. PMID 25600517 DOI: 10.1186/S12974-014-0226-Z  0.427
2015 Rathnasamy G, Sivakumar V, Foulds WS, Ling EA, Kaur C. Vascular changes in the developing rat retina in response to hypoxia. Experimental Eye Research. 130: 73-86. PMID 25433125 DOI: 10.1016/J.Exer.2014.11.011  0.548
2015 Du BL, Zeng X, Ma YH, Lai BQ, Wang JM, Ling EA, Wu JL, Zeng YS. Graft of the gelatin sponge scaffold containing genetically-modified neural stem cells promotes cell differentiation, axon regeneration, and functional recovery in rat with spinal cord transection. Journal of Biomedical Materials Research. Part A. 103: 1533-45. PMID 25046856 DOI: 10.1002/Jbm.A.35290  0.301
2015 Kaur C, Rathnasamy G, Foulds WS, Ling E. Cellular and Molecular Mechanisms of Retinal Ganglion Cell Death in Hypoxic-Ischemic Injuries Journal of Neuropathology and Experimental Neurology. DOI: 10.17756/Jnen.2015-003  0.54
2014 Yuan Y, Zha H, Rangarajan P, Ling EA, Wu C. Anti-inflammatory effects of Edaravone and Scutellarin in activated microglia in experimentally induced ischemia injury in rats and in BV-2 microglia. Bmc Neuroscience. 15: 125. PMID 25416145 DOI: 10.1186/S12868-014-0125-3  0.42
2014 Zou YY, Yuan Y, Kan EM, Lu J, Ling EA. Combustion smoke-induced inflammation in the olfactory bulb of adult rats. Journal of Neuroinflammation. 11: 176. PMID 25297558 DOI: 10.1186/S12974-014-0176-5  0.314
2014 Yang L, Kan EM, Lu J, Wu C, Ling EA. Expression of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) and its roles in activated microglia in vivo and in vitro. Journal of Neuroinflammation. 11: 148. PMID 25148928 DOI: 10.1186/S12974-014-0148-9  0.483
2014 Rathnasamy G, Sivakumar V, Rangarajan P, Foulds WS, Ling EA, Kaur C. NF-κB-mediated nitric oxide production and activation of caspase-3 cause retinal ganglion cell death in the hypoxic neonatal retina. Investigative Ophthalmology & Visual Science. 55: 5878-89. PMID 25139733 DOI: 10.1167/Iovs.13-13718  0.561
2014 Baby N, Patnala R, Ling EA, Dheen ST. Nanomedicine and its application in treatment of microglia-mediated neuroinflammation. Current Medicinal Chemistry. 21: 4215-26. PMID 25039775 DOI: 10.2174/0929867321666140716101258  0.363
2014 Rathnasamy G, Ling EA, Kaur C. Therapeutic implications of melatonin in cerebral edema. Histology and Histopathology. 29: 1525-38. PMID 24876075 DOI: 10.14670/Hh-29.1525  0.508
2014 Baby N, Li Y, Ling EA, Lu J, Dheen ST. Runx1t1 (Runt-related transcription factor 1; translocated to, 1) epigenetically regulates the proliferation and nitric oxide production of microglia. Plos One. 9: e89326. PMID 24586690 DOI: 10.1371/Journal.Pone.0089326  0.412
2014 Lai BQ, Wang JM, Ling EA, Wu JL, Zeng YS. Graft of a tissue-engineered neural scaffold serves as a promising strategy to restore myelination after rat spinal cord transection. Stem Cells and Development. 23: 910-21. PMID 24325427 DOI: 10.1089/Scd.2013.0426  0.306
2014 Rathnasamy G, Ling EA, Kaur C. Hypoxia inducible factor-1α mediates iron uptake which induces inflammatory response in amoeboid microglial cells in developing periventricular white matter through MAP kinase pathway. Neuropharmacology. 77: 428-40. PMID 24184387 DOI: 10.1016/J.Neuropharm.2013.10.024  0.576
2014 Kaur C, Sivakumar V, Zou Z, Ling EA. Microglia-derived proinflammatory cytokines tumor necrosis factor-alpha and interleukin-1beta induce Purkinje neuronal apoptosis via their receptors in hypoxic neonatal rat brain. Brain Structure & Function. 219: 151-70. PMID 23262920 DOI: 10.1007/S00429-012-0491-5  0.548
2013 Yao L, Kan EM, Kaur C, Dheen ST, Hao A, Lu J, Ling EA. Notch-1 signaling regulates microglia activation via NF-κB pathway after hypoxic exposure in vivo and in vitro. Plos One. 8: e78439. PMID 24223152 DOI: 10.1371/Journal.Pone.0078439  0.612
2013 Rathnasamy G, Ling EA, Kaur C. Consequences of iron accumulation in microglia and its implications in neuropathological conditions. Cns & Neurological Disorders Drug Targets. 12: 785-98. PMID 24047528 DOI: 10.2174/18715273113126660169  0.543
2013 Yao L, Cao Q, Wu C, Kaur C, Hao A, Ling EA. Notch signaling in the central nervous system with special reference to its expression in microglia. Cns & Neurological Disorders Drug Targets. 12: 807-14. PMID 24047525 DOI: 10.2174/18715273113126660172  0.589
2013 Murugan M, Ling EA, Kaur C. Glutamate receptors in microglia. Cns & Neurological Disorders Drug Targets. 12: 773-84. PMID 24047523 DOI: 10.2174/18715273113126660174  0.702
2013 Kaur C, Ling EA. Microglia--a therapeutic target in neurological diseases and disorders. Cns & Neurological Disorders Drug Targets. 12: 719. PMID 24047518 DOI: 10.2174/18715273113126660179  0.495
2013 Manivannan J, Tay SS, Ling EA, Dheen ST. Dihydropyrimidinase-like 3 regulates the inflammatory response of activated microglia. Neuroscience. 253: 40-54. PMID 23988434 DOI: 10.1016/j.neuroscience.2013.08.023  0.365
2013 Murugan M, Ling EA, Kaur C. Dysregulated glutamate uptake by astrocytes causes oligodendroglia death in hypoxic perventricular white matter damage. Molecular and Cellular Neurosciences. 56: 342-54. PMID 23859823 DOI: 10.1016/J.Mcn.2013.07.005  0.684
2013 Zou YY, Kan EM, Lu J, Ng KC, Tan MH, Yao L, Ling EA. Primary blast injury-induced lesions in the retina of adult rats. Journal of Neuroinflammation. 10: 79. PMID 23819902 DOI: 10.1186/1742-2094-10-79  0.417
2013 Zhang Y, Liu Q, Wang F, Ling EA, Liu S, Wang L, Yang Y, Yao L, Chen X, Wang F, Shi W, Gao M, Hao A. Melatonin antagonizes hypoxia-mediated glioblastoma cell migration and invasion via inhibition of HIF-1α. Journal of Pineal Research. 55: 121-30. PMID 23551342 DOI: 10.1111/Jpi.12052  0.353
2013 Yao L, Kan EM, Lu J, Hao A, Dheen ST, Kaur C, Ling EA. Toll-like receptor 4 mediates microglial activation and production of inflammatory mediators in neonatal rat brain following hypoxia: role of TLR4 in hypoxic microglia. Journal of Neuroinflammation. 10: 23. PMID 23388509 DOI: 10.1186/1742-2094-10-23  0.642
2013 Sivakumar V, Foulds WS, Luu CD, Ling EA, Kaur C. Hypoxia-induced retinal ganglion cell damage through activation of AMPA receptors and the neuroprotective effects of DNQX. Experimental Eye Research. 109: 83-97. PMID 23375774 DOI: 10.1016/J.Exer.2013.01.004  0.551
2013 Yuan Q, Zhao S, Wang F, Zhang H, Chen ZJ, Wang J, Wang Z, Du Z, Ling EA, Liu Q, Hao A. Palmitic acid increases apoptosis of neural stem cells via activating c-Jun N-terminal kinase. Stem Cell Research. 10: 257-66. PMID 23319068 DOI: 10.1016/J.Scr.2012.11.008  0.337
2013 Kaur C, Sivakumar V, Robinson R, Foulds WS, Luu CD, Ling EA. Neuroprotective effect of melatonin against hypoxia-induced retinal ganglion cell death in neonatal rats. Journal of Pineal Research. 54: 190-206. PMID 23113620 DOI: 10.1111/Jpi.12016  0.625
2013 Kaur C, Rathnasamy G, Ling EA. Roles of activated microglia in hypoxia induced neuroinflammation in the developing brain and the retina. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 8: 66-78. PMID 22367679 DOI: 10.1007/S11481-012-9347-2  0.637
2013 Kaur C, Ling EA. Glial cells: Embryonic development, types/functions and role in disease Glial Cells: Embryonic Development, Types/Functions and Role in Disease. 1-211.  0.483
2013 Rathnasamy G, Murugan M, Ling EA, Kaur C. Role of glial cells in periventricular white matter damage in hypoxic neonatal brains Glial Cells: Embryonic Development, Types/Functions and Role in Disease. 21-53.  0.668
2013 Kaur C, Ling EA. Preface Glial Cells: Embryonic Development, Types/Functions and Role in Disease. i-ii.  0.384
2013 Kaur C, Singh G, Sivakumar V, Ling EA. Hypoxia induced changes in the brain with special reference to the cerebellum Cerebellum: Anatomy, Functions and Disorders. 109-146.  0.517
2012 Yeo YA, Martínez Gómez JM, Croxford JL, Gasser S, Ling EA, Schwarz H. CD137 ligand activated microglia induces oligodendrocyte apoptosis via reactive oxygen species. Journal of Neuroinflammation. 9: 173. PMID 22799524 DOI: 10.1186/1742-2094-9-173  0.37
2012 Parakalan R, Jiang B, Nimmi B, Janani M, Jayapal M, Lu J, Tay SS, Ling EA, Dheen ST. Transcriptome analysis of amoeboid and ramified microglia isolated from the corpus callosum of rat brain. Bmc Neuroscience. 13: 64. PMID 22697290 DOI: 10.1186/1471-2202-13-64  0.384
2012 Tan B, Choi RH, Chin TJ, Kaur C, Ling EA. Manipulation of microglial activity as a therapy for Alzheimer's disease. Frontiers in Bioscience (Scholar Edition). 4: 1402-12. PMID 22652882 DOI: 10.2741/S342  0.542
2012 Kaur C, Sivakumar V, Foulds WS, Luu CD, Ling EA. Hypoxia-induced activation of N-methyl-D-aspartate receptors causes retinal ganglion cell death in the neonatal retina. Journal of Neuropathology and Experimental Neurology. 71: 330-47. PMID 22437343 DOI: 10.1097/Nen.0B013E31824Deb21  0.58
2012 Wang J, Hao H, Yao L, Zhang X, Zhao S, Ling EA, Hao A, Li G. Melatonin suppresses migration and invasion via inhibition of oxidative stress pathway in glioma cells. Journal of Pineal Research. 53: 180-7. PMID 22404622 DOI: 10.1111/J.1600-079X.2012.00985.X  0.318
2012 Wang J, Yao L, Zhao S, Zhang X, Yin J, Zhang Y, Chen X, Gao M, Ling EA, Hao A, Li G. Granulocyte-colony stimulating factor promotes proliferation, migration and invasion in glioma cells. Cancer Biology & Therapy. 13: 389-400. PMID 22313638 DOI: 10.4161/Cbt.19237  0.31
2012 Wang Z, Liu D, Wang J, Liu S, Gao M, Ling EA, Hao A. Cytoprotective effects of melatonin on astroglial cells subjected to palmitic acid treatment in vitro. Journal of Pineal Research. 52: 253-64. PMID 21929682 DOI: 10.1111/J.1600-079X.2011.00952.X  0.395
2012 Wang Z, Liu D, Wang F, Liu S, Zhao S, Ling EA, Hao A. Saturated fatty acids activate microglia via Toll-like receptor 4/NF-κB signalling. The British Journal of Nutrition. 107: 229-41. PMID 21733316 DOI: 10.1017/S0007114511002868  0.391
2012 Rathnasamy G, Ling EA, Kaur C. Microglia in the developing brain Microglia: Biology, Functions and Roles in Disease. 1-28.  0.505
2012 Murugan M, Ling EA, Kaur C. Role of cytokines in hypoxic periventricular white matter damage in developing brain Cytokines: Mechanisms, Functions and Abnormalities. 51-84.  0.653
2011 Rathnasamy G, Ling EA, Kaur C. Iron and iron regulatory proteins in amoeboid microglial cells are linked to oligodendrocyte death in hypoxic neonatal rat periventricular white matter through production of proinflammatory cytokines and reactive oxygen/nitrogen species. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 17982-95. PMID 22159112 DOI: 10.1523/Jneurosci.2250-11.2011  0.569
2011 Guo Y, Liu S, Wang P, Zhao S, Wang F, Bing L, Zhang Y, Ling EA, Gao J, Hao A. Expression profile of embryonic stem cell-associated genes Oct4, Sox2 and Nanog in human gliomas. Histopathology. 59: 763-75. PMID 22014056 DOI: 10.1111/J.1365-2559.2011.03993.X  0.329
2011 Cao Q, Kaur C, Wu CY, Lu J, Ling EA. Nuclear factor-kappa β regulates Notch signaling in production of proinflammatory cytokines and nitric oxide in murine BV-2 microglial cells. Neuroscience. 192: 140-54. PMID 21729740 DOI: 10.1016/J.Neuroscience.2011.06.060  0.539
2011 Deng YY, Lu J, Ling EA, Kaur C. Role of microglia in the process of inflammation in the hypoxic developing brain. Frontiers in Bioscience (Scholar Edition). 3: 884-900. PMID 21622239 DOI: 10.2741/194  0.63
2011 Rayan NA, Baby N, Pitchai D, Indraswari F, Ling EA, Lu J, Dheen T. Costunolide inhibits proinflammatory cytokines and iNOS in activated murine BV2 microglia. Frontiers in Bioscience (Elite Edition). 3: 1079-91. PMID 21622115 DOI: 10.2741/E312  0.796
2011 Huo Y, Rangarajan P, Ling EA, Dheen ST. Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia. Bmc Neuroscience. 12: 49. PMID 21615929 DOI: 10.1186/1471-2202-12-49  0.42
2011 Pun PB, Kan EM, Salim A, Li Z, Ng KC, Moochhala SM, Ling EA, Tan MH, Lu J. Low level primary blast injury in rodent brain. Frontiers in Neurology. 2: 19. PMID 21541261 DOI: 10.3389/Fneur.2011.00019  0.403
2011 Wang FW, Hao HB, Zhao SD, Zhang YM, Liu Q, Liu HJ, Liu SM, Yuan QH, Bing LJ, Ling EA, Hao AJ. Roles of activated astrocyte in neural stem cell proliferation and differentiation. Stem Cell Research. 7: 41-53. PMID 21530437 DOI: 10.1016/J.Scr.2011.03.004  0.367
2011 Sivakumar V, Foulds WS, Luu CD, Ling EA, Kaur C. Retinal ganglion cell death is induced by microglia derived pro-inflammatory cytokines in the hypoxic neonatal retina. The Journal of Pathology. 224: 245-60. PMID 21404274 DOI: 10.1002/Path.2858  0.581
2011 Fu J, Zhao SD, Liu HJ, Yuan QH, Liu SM, Zhang YM, Ling EA, Hao AJ. Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro. Journal of Pineal Research. 51: 104-12. PMID 21392094 DOI: 10.1111/J.1600-079X.2011.00867.X  0.369
2011 Zhao S, Yuan Q, Hao H, Guo Y, Liu S, Zhang Y, Wang J, Liu H, Wang F, Liu K, Ling EA, Hao A. Expression of OCT4 pseudogenes in human tumours: lessons from glioma and breast carcinoma. The Journal of Pathology. 223: 672-82. PMID 21341266 DOI: 10.1002/Path.2827  0.308
2011 Murugan M, Sivakumar V, Lu J, Ling EA, Kaur C. Expression of N-methyl D-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF-κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats. Glia. 59: 521-39. PMID 21319220 DOI: 10.1002/Glia.21121  0.72
2011 Lin H, Baby N, Lu J, Kaur C, Zhang C, Xu J, Ling EA, Dheen ST. Expression of sphingosine kinase 1 in amoeboid microglial cells in the corpus callosum of postnatal rats. Journal of Neuroinflammation. 8: 13. PMID 21310085 DOI: 10.1186/1742-2094-8-13  0.62
2011 Kaur C, Viswanathan S, Ling EA. Hypoxia-induced cellular and vascular changes in the nucleus tractus solitarius and ventrolateral medulla. Journal of Neuropathology and Experimental Neurology. 70: 201-17. PMID 21293297 DOI: 10.1097/Nen.0B013E31820D8F92  0.589
2011 Kaur C, Ling EA. Pineal gland, melatonin and hypoxia The Pineal Gland and Melatonin: Recent Advances in Development, Imaging, Disease and Treatment. 81-95.  0.453
2011 Kaur C, Ling EA. Structure and function of blood brain barrier in health and neuropathological conditions Brain Research Developments. 195-230.  0.463
2011 Kaur C, Ling EA. The pineal gland Brain Research Developments. 231-252.  0.409
2010 Cao Q, Li P, Lu J, Dheen ST, Kaur C, Ling EA. Nuclear factor-κB/p65 responds to changes in the Notch signaling pathway in murine BV-2 cells and in amoeboid microglia in postnatal rats treated with the γ-secretase complex blocker DAPT. Journal of Neuroscience Research. 88: 2701-14. PMID 20648656 DOI: 10.1002/Jnr.22429  0.546
2010 Deng YY, Lu J, Ling EA, Kaur C. Microglia-derived macrophage colony stimulating factor promotes generation of proinflammatory cytokines by astrocytes in the periventricular white matter in the hypoxic neonatal brain. Brain Pathology (Zurich, Switzerland). 20: 909-25. PMID 20406232 DOI: 10.1111/J.1750-3639.2010.00387.X  0.603
2010 Li JJ, Wu LH, Cao Q, Yuan Y, Yang L, Guo ZY, Kaur C, Sivakumar V, Ling EA, Wu CY. Endothelins-1/3 and endothelin-A/B receptors expressing glial cells with special reference to activated microglia in experimentally induced cerebral ischemia in the adult rats. Neuroscience. 167: 665-77. PMID 20206236 DOI: 10.1016/J.Neuroscience.2010.02.062  0.524
2010 Kaur C, Sivakumar V, Ling EA. Melatonin protects periventricular white matter from damage due to hypoxia. Journal of Pineal Research. 48: 185-93. PMID 20136703 DOI: 10.1111/J.1600-079X.2009.00740.X  0.567
2010 Li P, Kaur C, Lu J, Sivakumar V, Dheen ST, Ling EA. Expression of cyclooxygenase-2 and microsomal prostaglandin-E synthase in amoeboid microglial cells in the developing brain and effects of cyclooxygenase-2 neutralization on BV-2 microglial cells. Journal of Neuroscience Research. 88: 1577-94. PMID 20025057 DOI: 10.1002/Jnr.22319  0.63
2010 Gao Q, Lu J, Huo Y, Baby N, Ling EA, Dheen ST. NG2, a member of chondroitin sulfate proteoglycans family mediates the inflammatory response of activated microglia. Neuroscience. 165: 386-94. PMID 19878709 DOI: 10.1016/j.neuroscience.2009.10.022  0.332
2010 Sivakumar V, Ling EA, Lu J, Kaur C. Role of glutamate and its receptors and insulin-like growth factors in hypoxia induced periventricular white matter injury. Glia. 58: 507-23. PMID 19795501 DOI: 10.1002/Glia.20940  0.592
2009 Li P, Lu J, Kaur C, Sivakumar V, Tan KL, Ling EA. Expression of cyclooxygenase-1/-2, microsomal prostaglandin-E synthase-1 and E-prostanoid receptor 2 and regulation of inflammatory mediators by PGE(2) in the amoeboid microglia in hypoxic postnatal rats and murine BV-2 cells. Neuroscience. 164: 948-62. PMID 19712723 DOI: 10.1016/J.Neuroscience.2009.08.044  0.59
2009 Kaur C, Sivakumar V, Foulds WS, Luu CD, Ling EA. Cellular and vascular changes in the retina of neonatal rats after an acute exposure to hypoxia. Investigative Ophthalmology & Visual Science. 50: 5364-74. PMID 19474404 DOI: 10.1167/Iovs.09-3552  0.592
2009 Kaur C, Ling EA. Periventricular white matter damage in the hypoxic neonatal brain: role of microglial cells. Progress in Neurobiology. 87: 264-80. PMID 19428957 DOI: 10.1016/J.Pneurobio.2009.01.003  0.561
2009 Zou YY, Lu J, Poon DJ, Kaur C, Cao Q, Teo AL, Ling EA. Combustion smoke exposure induces up-regulated expression of vascular endothelial growth factor, aquaporin 4, nitric oxide synthases and vascular permeability in the retina of adult rats. Neuroscience. 160: 698-709. PMID 19285541 DOI: 10.1016/J.Neuroscience.2009.03.007  0.525
2009 Lu J, Goh SJ, Tng PY, Deng YY, Ling EA, Moochhala S. Systemic inflammatory response following acute traumatic brain injury. Frontiers in Bioscience (Landmark Edition). 14: 3795-813. PMID 19273311 DOI: 10.2741/3489  0.338
2009 Wu CY, Kaur C, Sivakumar V, Lu J, Ling EA. Kv1.1 expression in microglia regulates production and release of proinflammatory cytokines, endothelins and nitric oxide. Neuroscience. 158: 1500-8. PMID 19118603 DOI: 10.1016/J.Neuroscience.2008.11.043  0.592
2009 Li JJ, Lu J, Kaur C, Sivakumar V, Wu CY, Ling EA. Expression of angiotensin II and its receptors in the normal and hypoxic amoeboid microglial cells and murine BV-2 cells. Neuroscience. 158: 1488-99. PMID 19118600 DOI: 10.1016/J.Neuroscience.2008.11.046  0.57
2009 Du Z, Jia D, Liu S, Wang F, Li G, Zhang Y, Cao X, Ling EA, Hao A. Oct4 is expressed in human gliomas and promotes colony formation in glioma cells. Glia. 57: 724-33. PMID 18985733 DOI: 10.1002/Glia.20800  0.375
2009 Deng YY, Lu J, Ling EA, Kaur C. Monocyte chemoattractant protein-1 (MCP-1) produced via NF-kappaB signaling pathway mediates migration of amoeboid microglia in the periventricular white matter in hypoxic neonatal rats. Glia. 57: 604-21. PMID 18942743 DOI: 10.1002/Glia.20790  0.587
2009 Kaur C, Sivakumar V, Yip GW, Ling EA. Expression of syndecan-2 in the amoeboid microglial cells and its involvement in inflammation in the hypoxic developing brain. Glia. 57: 336-49. PMID 18803305 DOI: 10.1002/Glia.20764  0.591
2008 Kaur C, Foulds WS, Ling EA. Hypoxia-ischemia and retinal ganglion cell damage. Clinical Ophthalmology (Auckland, N.Z.). 2: 879-89. PMID 19668442 DOI: 10.2147/Opth.S3361  0.607
2008 Kaur C, Ling EA. Antioxidants and neuroprotection in the adult and developing central nervous system. Current Medicinal Chemistry. 15: 3068-80. PMID 19075654 DOI: 10.2174/092986708786848640  0.599
2008 Kaur C, Foulds WS, Ling EA. Blood-retinal barrier in hypoxic ischaemic conditions: basic concepts, clinical features and management. Progress in Retinal and Eye Research. 27: 622-47. PMID 18940262 DOI: 10.1016/J.Preteyeres.2008.09.003  0.5
2008 Li JJ, Lu J, Kaur C, Sivakumar V, Wu CY, Ling EA. Effects of hypoxia on expression of transforming growth factor-beta1 and its receptors I and II in the amoeboid microglial cells and murine BV-2 cells. Neuroscience. 156: 662-72. PMID 18760335 DOI: 10.1016/J.Neuroscience.2008.07.061  0.513
2008 Li F, Lu J, Wu CY, Kaur C, Sivakumar V, Sun J, Li S, Ling EA. Expression of Kv1.2 in microglia and its putative roles in modulating production of proinflammatory cytokines and reactive oxygen species. Journal of Neurochemistry. 106: 2093-105. PMID 18627436 DOI: 10.1111/J.1471-4159.2008.05559.X  0.602
2008 Jia DY, Du ZH, Liu SM, Liu HJ, Wang FW, Ling EA, Liu K, Hao AJ. c-Abl is involved in high glucose-induced apoptosis in embryonic E12.5 cortical neural progenitor cells from the mouse brain. Journal of Neurochemistry. 106: 1720-30. PMID 18624912 DOI: 10.1111/J.1471-4159.2008.05533.X  0.317
2008 Jia DY, Liu HJ, Wang FW, Liu SM, Ling EA, Liu K, Hao AJ. Folic acid supplementation affects apoptosis and differentiation of embryonic neural stem cells exposed to high glucose. Neuroscience Letters. 440: 27-31. PMID 18541378 DOI: 10.1016/J.Neulet.2008.05.053  0.31
2008 Cao Q, Lu J, Kaur C, Sivakumar V, Li F, Cheah PS, Dheen ST, Ling EA. Expression of Notch-1 receptor and its ligands Jagged-1 and Delta-1 in amoeboid microglia in postnatal rat brain and murine BV-2 cells. Glia. 56: 1224-37. PMID 18449946 DOI: 10.1002/Glia.20692  0.579
2008 Kaur C, Sivakumar V, Lu J, Tang FR, Ling EA. Melatonin attenuates hypoxia-induced ultrastructural changes and increased vascular permeability in the developing hippocampus. Brain Pathology (Zurich, Switzerland). 18: 533-47. PMID 18422758 DOI: 10.1111/J.1750-3639.2008.00156.X  0.538
2008 Deng Y, Lu J, Sivakumar V, Ling EA, Kaur C. Amoeboid microglia in the periventricular white matter induce oligodendrocyte damage through expression of proinflammatory cytokines via MAP kinase signaling pathway in hypoxic neonatal rats. Brain Pathology (Zurich, Switzerland). 18: 387-400. PMID 18371179 DOI: 10.1111/J.1750-3639.2008.00138.X  0.546
2008 Kaur C, Ling EA. Blood brain barrier in hypoxic-ischemic conditions. Current Neurovascular Research. 5: 71-81. PMID 18289024 DOI: 10.2174/156720208783565645  0.558
2008 Sivakumar V, Zhang Y, Ling EA, Foulds WS, Kaur C. Insulin-like growth factors, angiopoietin-2, and pigment epithelium-derived growth factor in the hypoxic retina. Journal of Neuroscience Research. 86: 702-11. PMID 17943991 DOI: 10.1002/Jnr.21519  0.5
2008 Sivakumar V, Lu J, Ling EA, Kaur C. Vascular endothelial growth factor and nitric oxide production in response to hypoxia in the choroid plexus in neonatal brain. Brain Pathology (Zurich, Switzerland). 18: 71-85. PMID 17924979 DOI: 10.1111/J.1750-3639.2007.00104.X  0.558
2007 Kaur C, Dheen ST, Ling EA. From blood to brain: amoeboid microglial cell, a nascent macrophage and its functions in developing brain. Acta Pharmacologica Sinica. 28: 1087-96. PMID 17640468 DOI: 10.1111/J.1745-7254.2007.00625.X  0.622
2007 Dheen ST, Kaur C, Ling EA. Microglial activation and its implications in the brain diseases. Current Medicinal Chemistry. 14: 1189-97. PMID 17504139 DOI: 10.2174/092986707780597961  0.609
2007 Zhou Y, Ling EA, Dheen ST. Dexamethasone suppresses monocyte chemoattractant protein-1 production via mitogen activated protein kinase phosphatase-1 dependent inhibition of Jun N-terminal kinase and p38 mitogen-activated protein kinase in activated rat microglia. Journal of Neurochemistry. 102: 667-78. PMID 17403137 DOI: 10.1111/J.1471-4159.2007.04535.X  0.379
2007 Li W, Zhang B, Tang J, Cao Q, Wu Y, Wu C, Guo J, Ling EA, Liang F. Sirtuin 2, a mammalian homolog of yeast silent information regulator-2 longevity regulator, is an oligodendroglial protein that decelerates cell differentiation through deacetylating alpha-tubulin. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2606-16. PMID 17344398 DOI: 10.1523/Jneurosci.4181-06.2007  0.337
2007 Cao Q, Ding P, Lu J, Dheen ST, Moochhala S, Ling EA. 2', 3'-Cyclic nucleotide 3'-phosphodiesterase cells derived from transplanted marrow stromal cells and host tissue contribute to perineurial compartment formation in injured rat spinal cord. Journal of Neuroscience Research. 85: 116-30. PMID 17061258 DOI: 10.1002/Jnr.21092  0.36
2006 Wu CY, Kaur C, Lu J, Cao Q, Guo CH, Zhou Y, Sivakumar V, Ling EA. Transient expression of endothelins in the amoeboid microglial cells in the developing rat brain. Glia. 54: 513-25. PMID 16897776 DOI: 10.1002/Glia.20402  0.575
2006 Lu J, Moochhala S, Moore XL, Ng KC, Tan MH, Lee LK, He B, Wong MC, Ling EA. Adult bone marrow cells differentiate into neural phenotypes and improve functional recovery in rats following traumatic brain injury. Neuroscience Letters. 398: 12-7. PMID 16455199 DOI: 10.1016/J.Neulet.2005.12.053  0.387
2004 Hu J, Chin CM, Png JC, Ng YK, Ling EA. The effect of chronic bladder outlet obstruction on neuronal nitric oxide synthase expression in the intramural ganglia of the guinea pig bladder. The Journal of Urology. 172: 1160-5. PMID 15311062 DOI: 10.1097/01.Ju.0000135047.65089.48  0.305
2003 Hsu JC, Lee YS, Chang CN, Ling EA, Lan CT. Sleep deprivation prior to transient global cerebral ischemia attenuates glial reaction in the rat hippocampal formation. Brain Research. 984: 170-81. PMID 12932851 DOI: 10.1016/S0006-8993(03)03128-7  0.328
2003 Hsu JC, Lee YS, Chang CN, Chuang HL, Ling EA, Lan CT. Sleep deprivation inhibits expression of NADPH-d and NOS while activating microglia and astroglia in the rat hippocampus. Cells, Tissues, Organs. 173: 242-54. PMID 12766354 DOI: 10.1159/000070380  0.307
2002 Luo Y, Kaur C, Ling EA. Neuronal and glial response in the rat hypothalamus-neurohypophysis complex with streptozotocin-induced diabetes. Brain Research. 925: 42-54. PMID 11755899 DOI: 10.1016/S0006-8993(01)03258-9  0.568
2001 Hao A, Dheen ST, Ling E. Induction of cytokine expression in the brain macrophages/amoeboid microglia of the fetal rat exposed to a teratogen. Neuroreport. 12: 1391-1397. PMID 11388417 DOI: 10.1097/00001756-200105250-00020  0.378
2001 Lu J, Moochhala S, Kaur C, Ling E. Cellular inflammatory response associated with breakdown of the blood-brain barrier after closed head injury in rats. Journal of Neurotrauma. 18: 399-408. PMID 11336441 DOI: 10.1089/089771501750170976  0.603
2001 Hao A, Dheen ST, Ling E. Response of amoeboid microglia/brain macrophages in fetal rat brain exposed to a teratogen Journal of Neuroscience Research. 64: 79-93. PMID 11276054 DOI: 10.1002/Jnr.1056  0.437
2000 Lu J, Moochhala S, Kaur C, Ling E. Changes in apoptosis-related protein (p53, Bax, Bcl-2 and Fos) expression with DNA fragmentation in the central nervous system in rats after closed head injury Neuroscience Letters. 290: 89-92. PMID 10936684 DOI: 10.1016/S0304-3940(00)01307-0  0.575
2000 Zeng XX, Ng YK, Ling EA. Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats. Visual Neuroscience. 17: 463-71. PMID 10910112 DOI: 10.1017/S0952523800173122  0.332
2000 Zeng XX, Ng YK, Ling EA. Labelling of retinal microglial cells following an intravenous injection of a fluorescent dye into rats of different ages. Journal of Anatomy. 196: 173-9. PMID 10739013 DOI: 10.1046/J.1469-7580.2000.19620173.X  0.327
2000 Gao Y, Ng YK, Lin JY, Ling EA. Expression of immunoregulatory cytokines in neurons of the lateral hypothalamic area and amygdaloid nuclear complex of rats immunized against human IgG. Brain Research. 859: 364-8. PMID 10719087 DOI: 10.1016/S0006-8993(00)02001-1  0.344
1999 Bay B, Lee Y, Tan BK, Ling E. Lipid peroxidative stress and antioxidative enzymes in brains of milk-supplemented rats Neuroscience Letters. 277: 127-130. PMID 10624826 DOI: 10.1016/S0304-3940(99)00872-1  0.332
1999 Ng YK, Ling EA. Emperipolesis of lymphoid cells in vagal efferent neurons following an intraneural injection of ricin into the vagus nerve in rats. Neuroscience Letters. 270: 153-6. PMID 10462117 DOI: 10.1016/S0304-3940(99)00490-5  0.32
1999 Zhou Y, Ling E. Neuronal nitric oxide synthase in the neural pathways of the urinary bladder. Journal of Anatomy. 194: 481-496. PMID 10445817 DOI: 10.1046/J.1469-7580.1999.19440481.X  0.314
1999 Wu YP, McRae A, Rudolphi K, Ling EA. Propentofylline attenuates microglial reaction in the rat spinal cord induced by middle cerebral artery occlusion. Neuroscience Letters. 260: 17-20. PMID 10027689 DOI: 10.1016/S0304-3940(98)00941-0  0.339
1998 Li Y, Kaur C, Ling E. Neuronal degeneration and microglial reaction in the fetal and postnatal rat brain after transient maternal hypoxia. Neuroscience Research. 32: 137-148. PMID 9858021 DOI: 10.1016/S0168-0102(98)00077-7  0.605
1998 Ling E, Kaur C, Lu J. Origin, nature, and some functional considerations of intraventricular macrophages, with special reference to the epiplexus cells Microscopy Research and Technique. 41: 43-56. PMID 9550136 DOI: 10.1002/(Sici)1097-0029(19980401)41:1<43::Aid-Jemt5>3.0.Co;2-V  0.609
1998 McRae A, Ling E, Schubert P, Rudolphi K. Properties of activated microglia and pharmacologic interference by propentofylline. Alzheimer Disease & Associated Disorders. 12: 15-20. DOI: 10.1097/00002093-199803001-00003  0.418
1997 Li Y, Kaur C, Ling E. Labeling of amoeboid microglial cells and intraventricular macrophages in fetal rats following a maternal injection of a fluorescent dye Neuroscience Research. 28: 119-125. PMID 9220469 DOI: 10.1016/S0168-0102(97)00035-7  0.582
1997 Ng YK, Ling EA. Induction of major histocompatibility class II antigen on microglial cells in postnatal and adult rats following intraperitoneal injections of lipopolysaccharide. Neuroscience Research. 28: 111-8. PMID 9220468 DOI: 10.1016/S0168-0102(97)00033-3  0.388
1997 Htain WW, Leong S, Ling E. In vivo expression of inducible nitric oxide synthase in supraventricular amoeboid microglial cells in neonatal BALB/c and athymic mice. Neuroscience Letters. 223: 53-56. PMID 9058421 DOI: 10.1016/S0304-3940(97)13387-0  0.327
1996 Kaur C, Singh J, Lim MK, Ng BL, Yap EPH, Ling E. Studies of the Choroid Plexus and Its Associated Epiplexus Cells in the Lateral Ventricles of Rats Following an Exposure to a Single Non-Penetrative Blast. Archives of Histology and Cytology. 59: 239-248. PMID 8874756 DOI: 10.1679/Aohc.59.239  0.576
1996 Lan C, Shieh J, Wen C, Tan C, Ling E. Ultrastructural localization of acetylcholinesterase and choline acetyltransferase in oligodendrocytes, glioblasts and vascular endothelial cells in the external cuneate nucleus of the gerbil Anatomy and Embryology. 194: 177-185. PMID 8827326 DOI: 10.1007/Bf00195011  0.332
1996 Wang X, Wong W, Ling E. NADPH-diaphorase activity in the nodose ganglion of normal and vagotomized guinea-pigs. Cell and Tissue Research. 285: 141-147. PMID 8766867 DOI: 10.1007/S004410050629  0.304
1995 Htain W, Leong S, Ling E. A qualitative and quantitative study of the glial cells in normal and athymic mice. Glia. 15: 11-21. PMID 8847097 DOI: 10.1002/Glia.440150103  0.376
1995 Lu J, Kaur C, Ling E. Histochemical demonstration of nitric oxide synthase-like immunoreactivity in epiplexus cells and choroid epithelia in the lateral ventricles of postnatal rat brain induced by an intracerebral injection of lipopolysaccharide Brain Research. 699: 275-285. PMID 8616631 DOI: 10.1016/0006-8993(95)00919-H  0.588
1994 Htain W, Leong S, Ling E. A comparative Mac‐1 immunocytochemical and lectin histochemical study of microglial cells in the normal and athymic mice Glia. 12: 44-51. PMID 7843786 DOI: 10.1002/Glia.440120106  0.323
1993 Ling EA, Wong WC. The origin and nature of ramified and amoeboid microglia: a historical review and current concepts Glia. 7: 9-18. PMID 8423067 DOI: 10.1002/Glia.440070105  0.389
1992 Leong S, Ling E. Amoeboid and ramified microglia: Their interrelationship and response to brain injury Glia. 6: 39-47. PMID 1380949 DOI: 10.1002/Glia.440060106  0.41
1988 Ling EA, Wong WC. An electron microscopic study of the nodose (inferior vagal) ganglion cells in the monkey Journal of Neurocytology. 17: 845-857. PMID 3230402 DOI: 10.1007/Bf01216711  0.336
1981 Ling E. The Origin and Nature of Microglia Advances in Cell Biology. 2: 33-82. DOI: 10.1016/B978-0-12-008302-2.50007-9  0.408
1980 Ling EA, Penney D, Leblond CP. Use of carbon labeling to demonstrate the role of blood monocytes as precursors of the 'ameboid cells' present in the corpus callosum of postnatal rats. The Journal of Comparative Neurology. 193: 631-57. PMID 6969268 DOI: 10.1002/cne.901930304  0.495
1973 Paterson JA, Privat A, Ling EA, Leblond CP. Investigation of glial cells in semithin sections. 3. Transformation of subependymal cells into glial cells, as shown by radioautography after 3 H-thymidine injection into the lateral ventricle of the brain of young rats. The Journal of Comparative Neurology. 149: 83-102. PMID 4573360 DOI: 10.1002/cne.901490106  0.521
1973 Ling EA, Leblond CP. Investigation of glial cells in semithin sections. II. Variation with age in the numbers of the various glial cell types in rat cortex and corpus callosum. The Journal of Comparative Neurology. 149: 73-81. PMID 4121706 DOI: 10.1002/Cne.901490105  0.54
1973 Ling EA, Paterson JA, Privat A, Mori S, Leblond CP. Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats. The Journal of Comparative Neurology. 149: 43-71. PMID 4121705 DOI: 10.1002/cne.901490104  0.532
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