Ira J. Goldberg - Publications

Affiliations: 
Endocrinology, Diabetes and Metabolism New York University Langone Medical Center 

78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Da Dalt L, Cabodevilla AG, Goldberg IJ, Norata GD. Cardiac lipid metabolism, mitochondrial function, and heart failure. Cardiovascular Research. 119: 1905-1914. PMID 37392421 DOI: 10.1093/cvr/cvad100  0.414
2022 Oluwadare J, Cabodevilla AG, Son NH, Hu Y, Mullick AE, Verano M, Alemán JO, Ramasamy R, Goldberg IJ. "Blocking lipid uptake pathways does not prevent toxicity in adipose triglyceride lipase (ATGL) deficiency". Journal of Lipid Research. 100274. PMID 36115595 DOI: 10.1016/j.jlr.2022.100274  0.425
2022 Cifarelli V, Kuda O, Yang K, Liu X, Gross RW, Pietka TA, Heo GS, Sultan D, Luehmann H, Lesser J, Ross M, Goldberg IJ, Gropler RJ, Liu Y, Abumrad NA. Cardiac immune cell infiltration associates with abnormal lipid metabolism. Frontiers in Cardiovascular Medicine. 9: 948332. PMID 36061565 DOI: 10.3389/fcvm.2022.948332  0.328
2022 Takahashi M, Yamamuro D, Wakabayashi T, Takei A, Takei S, Nagashima S, Okazaki H, Ebihara K, Yagyu H, Takayanagi Y, Onaka T, Goldberg IJ, Ishibashi S. Loss of myeloid lipoprotein lipase exacerbates adipose tissue fibrosis with collagen VI deposition and hyperlipidemia in leptin-deficient obese mice. The Journal of Biological Chemistry. 298: 102322. PMID 35926714 DOI: 10.1016/j.jbc.2022.102322  0.307
2021 Shimizu-Albergine M, Basu D, Kanter JE, Kramer F, Kothari V, Barnhart S, Thornock C, Mullick AE, Clouet-Foraison N, Vaisar T, Heinecke JW, Hegele RA, Goldberg IJ, Bornfeldt KE. CREBH normalizes dyslipidemia and halts atherosclerosis in diabetes by decreasing circulating remnant lipoproteins. The Journal of Clinical Investigation. PMID 34491909 DOI: 10.1172/JCI153285  0.303
2021 Cabodevilla AG, Tang S, Lee S, Mullick AE, Aleman JO, Hussain MM, Sessa WC, Abumrad NA, Goldberg IJ. Eruptive xanthoma model reveals endothelial cells internalize and metabolize chylomicrons, leading to extravascular triglyceride accumulation. The Journal of Clinical Investigation. 131. PMID 34128469 DOI: 10.1172/JCI145800  0.311
2021 Kyriazis ID, Hoffman M, Gaignebet L, Lucchese AM, Markopoulou E, Palioura D, Wang C, Bannister TD, Christofidou-Solomidou M, Oka SI, Sadoshima J, Koch WJ, Goldberg IJ, Yang VW, Bialkowska AB, et al. KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy. Circulation Research. 128: 335-357. PMID 33539225 DOI: 10.1161/CIRCRESAHA.120.316738  0.731
2021 Abumrad NA, Cabodevilla AG, Samovski D, Pietka T, Basu D, Goldberg IJ. Endothelial Cell Receptors in Tissue Lipid Uptake and Metabolism. Circulation Research. 128: 433-450. PMID 33539224 DOI: 10.1161/CIRCRESAHA.120.318003  0.307
2021 Hoffman M, Palioura D, Kyriazis ID, Cimini M, Badolia R, Rajan S, Gao E, Nikolaidis N, Schulze PC, Goldberg IJ, Kishore R, Yang VW, Bannister TD, Bialkowska AB, Selzman CH, et al. Cardiomyocyte Krüppel-like Factor 5 Promotes De Novo Ceramide Biosynthesis and Contributes to Eccentric Remodeling in Ischemic Cardiomyopathy. Circulation. PMID 33430631 DOI: 10.1161/CIRCULATIONAHA.120.047420  0.764
2019 Pennig J, Scherrer P, Gissler MC, Anto-Michel N, Hoppe N, Füner L, Härdtner C, Stachon P, Wolf D, Hilgendorf I, Mullick A, Bode C, Zirlik A, Goldberg IJ, Willecke F. Glucose lowering by SGLT2-inhibitor empagliflozin accelerates atherosclerosis regression in hyperglycemic STZ-diabetic mice. Scientific Reports. 9: 17937. PMID 31784656 DOI: 10.1038/s41598-019-54224-9  0.329
2019 Kalliora C, Kyriazis ID, Oka SI, Lieu MJ, Yue Y, Area-Gomez E, Pol CJ, Tian Y, Mizushima W, Chin A, Scerbo D, Schulze PC, Civelek M, Sadoshima J, Madesh M, ... Goldberg IJ, et al. Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction. Jci Insight. 5. PMID 31393858 DOI: 10.1172/Jci.Insight.129556  0.746
2019 Pol CJ, Pollak NM, Jurczak MJ, Zacharia E, Karagiannides I, Kyriazis ID, Ntziachristos P, Scerbo DA, Brown BR, Aifantis I, Shulman GI, Goldberg IJ, Drosatos K. Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 31029826 DOI: 10.1016/J.Bbadis.2019.04.010  0.725
2018 Son NH, Basu D, Samovski D, Pietka TA, Peche VS, Willecke F, Fang X, Yu SQ, Scerbo D, Chang HR, Sun F, Bagdasarov S, Drosatos K, Yeh ST, Mullick AE, ... ... Goldberg IJ, et al. Endothelial cell CD36 optimizes tissue fatty acid uptake. The Journal of Clinical Investigation. PMID 30047927 DOI: 10.1172/JCI99315  0.645
2018 Yuan C, Hu J, Parathath S, Grauer L, Cassella CB, Bagdasarov S, Goldberg IJ, Ramasamy R, Fisher EA. Human Aldose Reductase Expression Prevents Atherosclerosis Regression in Diabetic Mice. Diabetes. PMID 29891593 DOI: 10.2337/Db18-0156  0.348
2018 Pollak NM, Hoffman M, Goldberg IJ, Drosatos K. Krüppel-like factors: Crippling and un-crippling metabolic pathways. Jacc. Basic to Translational Science. 3: 132-156. PMID 29876529 DOI: 10.1016/j.jacbts.2017.09.001  0.692
2018 Goldberg IJ. 2017 George Lyman Duff Memorial Lecture: Fat in the Blood, Fat in the Artery, Fat in the Heart: Triglyceride in Physiology and Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 700-706. PMID 29419410 DOI: 10.1161/ATVBAHA.117.309666  0.364
2017 Ji R, Akashi H, Drosatos K, Liao X, Jiang H, Kennel PJ, Brunjes DL, Castillero E, Zhang X, Deng LY, Homma S, George IJ, Takayama H, Naka Y, Goldberg IJ, et al. Increased de novo ceramide synthesis and accumulation in failing myocardium. Jci Insight. 2. PMID 28724803 DOI: 10.1172/Jci.Insight.96203  0.702
2017 Ji R, Akashi H, Drosatos K, Liao X, Jiang H, Kennel PJ, Brunjes DL, Castillero E, Zhang X, Deng LY, Homma S, George IJ, Takayama H, Naka Y, Goldberg IJ, et al. Increased de novo ceramide synthesis and accumulation in failing myocardium. Jci Insight. 2. PMID 28469091 DOI: 10.1172/jci.insight.82922  0.702
2017 Scerbo D, Son NH, Sirwi A, Zeng L, Sas KM, Cifarelli V, Schoiswohl G, Huggins LA, Gumaste N, Hu Y, Pennathur S, Abumrad NA, Kershaw EE, Hussain MM, Susztak K, ... Goldberg IJ, et al. Kidney triglyceride accumulation in the fasted mouse is dependent upon serum free fatty acids. Journal of Lipid Research. PMID 28404638 DOI: 10.1194/Jlr.M074427  0.305
2017 Yu T, Sungelo MJ, Goldberg IJ, Wang H, Eckel RH. Streptozotocin-Treated High Fat Fed Mice: A New Type 2 Diabetes Model Used to Study Canagliflozin-Induced Alterations in Lipids and Lipoproteins. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Metabolisme. PMID 28395380 DOI: 10.1055/S-0042-110934  0.33
2016 Schulze PC, Drosatos K, Goldberg IJ. Lipid Use and Misuse by the Heart. Circulation Research. 118: 1736-51. PMID 27230639 DOI: 10.1161/CIRCRESAHA.116.306842  0.714
2016 Abumrad NA, Goldberg IJ. CD36 actions in the heart: Lipids, calcium, inflammation, repair and more? Biochimica Et Biophysica Acta. 1860: 1442-9. PMID 27004753 DOI: 10.1016/j.bbalip.2016.03.015  0.315
2015 Drosatos K, Pollak NM, Pol C, Ntziachristos P, Willecke F, Valenti MC, Trent CM, Hu Y, Guo S, Aifantis I, Goldberg IJ. Cardiac Myocyte KLF5 Regulates Ppara Expression and Cardiac Function. Circulation Research. PMID 26574507 DOI: 10.1161/Circresaha.115.306383  0.722
2015 Willecke F, Yuan C, Oka K, Chan L, Hu Y, Barnhart S, Bornfeldt KE, Goldberg IJ, Fisher EA. Effects of High Fat Feeding and Diabetes on Regression of Atherosclerosis Induced by Low-Density Lipoprotein Receptor Gene Therapy in LDL Receptor-Deficient Mice. Plos One. 10: e0128996. PMID 26046657 DOI: 10.1371/journal.pone.0128996  0.357
2015 Stadler K, Goldberg IJ, Susztak K. The evolving understanding of the contribution of lipid metabolism to diabetic kidney disease. Current Diabetes Reports. 15: 40. PMID 25957525 DOI: 10.1007/s11892-015-0611-8  0.31
2015 Kolwicz SC, Liu L, Goldberg IJ, Tian R. Enhancing Cardiac Triacylglycerol Metabolism Improves Recovery From Ischemic Stress. Diabetes. PMID 25858561 DOI: 10.2337/db14-1943  0.429
2015 Drosatos K, Lymperopoulos A, Kennel PJ, Pollak N, Schulze PC, Goldberg IJ. Pathophysiology of sepsis-related cardiac dysfunction: driven by inflammation, energy mismanagement, or both? Current Heart Failure Reports. 12: 130-40. PMID 25475180 DOI: 10.1007/s11897-014-0247-z  0.668
2015 Willecke F, Scerbo D, Nagareddy P, Obunike JC, Barrett TJ, Abdillahi ML, Trent CM, Huggins LA, Fisher EA, Drosatos K, Goldberg IJ. Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 35: 102-10. PMID 25395613 DOI: 10.1161/ATVBAHA.114.304615  0.638
2014 Lee SA, Jiang H, Trent CM, Yuen JJ, Narayanasamy S, Curley RW, Harrison EH, Goldberg IJ, Maurer MS, Blaner WS. Cardiac dysfunction in β-carotene-15,15'-dioxygenase-deficient mice is associated with altered retinoid and lipid metabolism. American Journal of Physiology. Heart and Circulatory Physiology. 307: H1675-84. PMID 25260612 DOI: 10.1152/Ajpheart.00548.2014  0.375
2014 Bosma M, Dapito DH, Drosatos-Tampakaki Z, Huiping-Son N, Huang LS, Kersten S, Drosatos K, Goldberg IJ. Sequestration of fatty acids in triglycerides prevents endoplasmic reticulum stress in an in vitro model of cardiomyocyte lipotoxicity. Biochimica Et Biophysica Acta. 1841: 1648-55. PMID 25251292 DOI: 10.1016/j.bbalip.2014.09.012  0.645
2014 Liu L, Trent CM, Fang X, Son NH, Jiang H, Blaner WS, Hu Y, Yin YX, Farese RV, Homma S, Turnbull AV, Eriksson JW, Hu SL, Ginsberg HN, Huang LS, ... Goldberg IJ, et al. Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure. The Journal of Biological Chemistry. 289: 29881-91. PMID 25157099 DOI: 10.1074/jbc.M114.601864  0.457
2014 Trent CM, Yu S, Hu Y, Skoller N, Huggins LA, Homma S, Goldberg IJ. Lipoprotein lipase activity is required for cardiac lipid droplet production. Journal of Lipid Research. 55: 645-58. PMID 24493834 DOI: 10.1194/jlr.M043471  0.439
2014 Drosatos-Tampakaki Z, Drosatos K, Siegelin Y, Gong S, Khan S, Van Dyke T, Goldberg IJ, Schulze PC, Schulze-Späte U. Palmitic acid and DGAT1 deficiency enhance osteoclastogenesis, while oleic acid-induced triglyceride formation prevents it. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 29: 1183-95. PMID 24272998 DOI: 10.1002/jbmr.2150  0.663
2014 Vedantham S, Thiagarajan D, Ananthakrishnan R, Wang L, Rosario R, Zou YS, Goldberg I, Yan SF, Schmidt AM, Ramasamy R. Aldose reductase drives hyperacetylation of Egr-1 in hyperglycemia and consequent upregulation of proinflammatory and prothrombotic signals. Diabetes. 63: 761-74. PMID 24186862 DOI: 10.2337/Db13-0032  0.301
2013 Khan RS, Lin Y, Hu Y, Son NH, Bharadwaj KG, Palacios C, Chokshi A, Ji R, Yu S, Homma S, Schulze PC, Tian R, Goldberg IJ. Rescue of heart lipoprotein lipase-knockout mice confirms a role for triglyceride in optimal heart metabolism and function. American Journal of Physiology. Endocrinology and Metabolism. 305: E1339-47. PMID 24085031 DOI: 10.1152/ajpendo.00349.2013  0.465
2013 Drosatos K, Khan RS, Trent CM, Jiang H, Son NH, Blaner WS, Homma S, Schulze PC, Goldberg IJ. Peroxisome proliferator-activated receptor-γ activation prevents sepsis-related cardiac dysfunction and mortality in mice. Circulation. Heart Failure. 6: 550-62. PMID 23572494 DOI: 10.1161/CIRCHEARTFAILURE.112.000177  0.681
2013 Khan RS, Chokshi A, Drosatos K, Jiang H, Yu S, Harris CR, Schulze PC, Homma S, Blaner WS, Shulman GI, Huang LS, Goldberg IJ. Fish oil selectively improves heart function in a mouse model of lipid-induced cardiomyopathy. Journal of Cardiovascular Pharmacology. 61: 345-54. PMID 23567901 DOI: 10.1097/Fjc.0B013E318283D845  0.727
2013 Garcia-Arcos I, Hiyama Y, Drosatos K, Bharadwaj KG, Hu Y, Son NH, O'Byrne SM, Chang CL, Deckelbaum RJ, Takahashi M, Westerterp M, Obunike JC, Jiang H, Yagyu H, Blaner WS, ... Goldberg IJ, et al. Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology. The Journal of Biological Chemistry. 288: 14046-58. PMID 23542081 DOI: 10.1074/Jbc.M113.469270  0.666
2012 Son NH, Ananthakrishnan R, Yu S, Khan RS, Jiang H, Ji R, Akashi H, Li Q, O'Shea K, Homma S, Goldberg IJ, Ramasamy R. Cardiomyocyte aldose reductase causes heart failure and impairs recovery from ischemia. Plos One. 7: e46549. PMID 23029549 DOI: 10.1371/Journal.Pone.0046549  0.494
2012 Park TS, Goldberg IJ. Sphingolipids, lipotoxic cardiomyopathy, and cardiac failure. Heart Failure Clinics. 8: 633-41. PMID 22999245 DOI: 10.1016/j.hfc.2012.06.003  0.308
2012 Goldberg IJ, Trent CM, Schulze PC. Lipid metabolism and toxicity in the heart. Cell Metabolism. 15: 805-12. PMID 22682221 DOI: 10.1016/j.cmet.2012.04.006  0.428
2012 Liu L, Yu S, Khan RS, Homma S, Schulze PC, Blaner WS, Yin Y, Goldberg IJ. Diacylglycerol acyl transferase 1 overexpression detoxifies cardiac lipids in PPARγ transgenic mice. Journal of Lipid Research. 53: 1482-92. PMID 22628613 DOI: 10.1194/jlr.M024208  0.447
2012 Chokshi A, Drosatos K, Cheema FH, Ji R, Khawaja T, Yu S, Kato T, Khan R, Takayama H, Knöll R, Milting H, Chung CS, Jorde U, Naka Y, Mancini DM, ... Goldberg IJ, et al. Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure. Circulation. 125: 2844-53. PMID 22586279 DOI: 10.1161/CIRCULATIONAHA.111.060889  0.7
2012 Lee SY, Kim JR, Hu Y, Khan R, Kim SJ, Bharadwaj KG, Davidson MM, Choi CS, Shin KO, Lee YM, Park WJ, Park IS, Jiang XC, Goldberg IJ, Park TS. Cardiomyocyte specific deficiency of serine palmitoyltransferase subunit 2 reduces ceramide but leads to cardiac dysfunction. The Journal of Biological Chemistry. 287: 18429-39. PMID 22493506 DOI: 10.1074/jbc.M111.296947  0.483
2011 Morrow JP, Katchman A, Son NH, Trent CM, Khan R, Shiomi T, Huang H, Amin V, Lader JM, Vasquez C, Morley GE, D'Armiento J, Homma S, Goldberg IJ, Marx SO. Mice with cardiac overexpression of peroxisome proliferator-activated receptor γ have impaired repolarization and spontaneous fatal ventricular arrhythmias. Circulation. 124: 2812-21. PMID 22124376 DOI: 10.1161/Circulationaha.111.056309  0.446
2011 Drosatos K, Drosatos-Tampakaki Z, Khan R, Homma S, Schulze PC, Zannis VI, Goldberg IJ. Inhibition of c-Jun-N-terminal kinase increases cardiac peroxisome proliferator-activated receptor alpha expression and fatty acid oxidation and prevents lipopolysaccharide-induced heart dysfunction. The Journal of Biological Chemistry. 286: 36331-9. PMID 21873422 DOI: 10.1074/Jbc.M111.272146  0.763
2011 Khan RS, Schulze PC, Bokhari S, Goldberg IJ. A sweet heart: Increased cardiac glucose uptake in patients with lipoprotein lipase deficiency Journal of Nuclear Cardiology. 18: 1107-1110. PMID 21845510 DOI: 10.1007/s12350-011-9442-4  0.339
2011 Vedantham S, Noh H, Ananthakrishnan R, Son N, Hallam K, Hu Y, Yu S, Shen X, Rosario R, Lu Y, Ravindranath T, Drosatos K, Huggins LA, Schmidt AM, Goldberg IJ, et al. Human aldose reductase expression accelerates atherosclerosis in diabetic apolipoprotein E-/- mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 1805-13. PMID 21636809 DOI: 10.1161/Atvbaha.111.226902  0.677
2011 Liu L, Yu S, Khan RS, Ables GP, Bharadwaj KG, Hu Y, Huggins LA, Eriksson JW, Buckett LK, Turnbull AV, Ginsberg HN, Blaner WS, Huang LS, Goldberg IJ. DGAT1 deficiency decreases PPAR expression and does not lead to lipotoxicity in cardiac and skeletal muscle. Journal of Lipid Research. 52: 732-44. PMID 21205704 DOI: 10.1194/jlr.M011395  0.372
2011 Wang H, Astarita G, Taussig MD, Bharadwaj KG, DiPatrizio NV, Nave KA, Piomelli D, Goldberg IJ, Eckel RH. Deficiency of lipoprotein lipase in neurons modifies the regulation of energy balance and leads to obesity. Cell Metabolism. 13: 105-13. PMID 21195353 DOI: 10.1016/J.Cmet.2010.12.006  0.318
2011 Drosatos K, Bharadwaj KG, Lymperopoulos A, Ikeda S, Khan R, Hu Y, Agarwal R, Yu S, Jiang H, Steinberg SF, Blaner WS, Koch WJ, Goldberg IJ. Cardiomyocyte lipids impair β-adrenergic receptor function via PKC activation American Journal of Physiology - Endocrinology and Metabolism. 300: E489-E499. PMID 21139071 DOI: 10.1152/ajpendo.00569.2010  0.666
2010 Son NH, Yu S, Tuinei J, Arai K, Hamai H, Homma S, Shulman GI, Abel ED, Goldberg IJ. PPARγ-induced cardiolipotoxicity in mice is ameliorated by PPARα deficiency despite increases in fatty acid oxidation. The Journal of Clinical Investigation. 120: 3443-54. PMID 20852389 DOI: 10.1172/Jci40905  0.476
2010 Bharadwaj KG, Hiyama Y, Hu Y, Huggins LA, Ramakrishnan R, Abumrad NA, Shulman GI, Blaner WS, Goldberg IJ. Chylomicron- and VLDL-derived lipids enter the heart through different pathways: in vivo evidence for receptor- and non-receptor-mediated fatty acid uptake. The Journal of Biological Chemistry. 285: 37976-86. PMID 20852327 DOI: 10.1074/Jbc.M110.174458  0.313
2010 Ramasamy R, Goldberg IJ. Aldose reductase and cardiovascular diseases, creating human-like diabetic complications in an experimental model. Circulation Research. 106: 1449-58. PMID 20466987 DOI: 10.1161/Circresaha.109.213447  0.303
2010 Iliopoulos D, Drosatos K, Hiyama Y, Goldberg IJ, Zannis VI. MicroRNA-370 controls the expression of microRNA-122 and Cpt1alpha and affects lipid metabolism. Journal of Lipid Research. 51: 1513-23. PMID 20124555 DOI: 10.1194/Jlr.M004812  0.671
2010 Duncan JG, Bharadwaj KG, Fong JL, Mitra R, Sambandam N, Courtois MR, Lavine KJ, Goldberg IJ, Kelly DP. Rescue of cardiomyopathy in peroxisome proliferator-activated receptor-alpha transgenic mice by deletion of lipoprotein lipase identifies sources of cardiac lipids and peroxisome proliferator-activated receptor-alpha activators. Circulation. 121: 426-35. PMID 20065164 DOI: 10.1161/Circulationaha.109.888735  0.448
2010 Khan RS, Drosatos K, Goldberg IJ. Creating and curing fatty hearts Current Opinion in Clinical Nutrition and Metabolic Care. 13: 145-149. PMID 20010095 DOI: 10.1097/MCO.0b013e3283357272  0.343
2009 Liu L, Shi X, Bharadwaj KG, Ikeda S, Yamashita H, Yagyu H, Schaffer JE, Yu YH, Goldberg IJ. DGAT1 expression increases heart triglyceride content but ameliorates lipotoxicity. The Journal of Biological Chemistry. 284: 36312-23. PMID 19778901 DOI: 10.1074/Jbc.M109.049817  0.473
2009 Noh HL, Hu Y, Park TS, DiCioccio T, Nichols AJ, Okajima K, Homma S, Goldberg IJ. Regulation of plasma fructose and mortality in mice by the aldose reductase inhibitor lidorestat. The Journal of Pharmacology and Experimental Therapeutics. 328: 496-503. PMID 18974362 DOI: 10.1124/jpet.108.136283  0.325
2008 Yamashita H, Bharadwaj KG, Ikeda S, Park TS, Goldberg IJ. Cardiac metabolic compensation to hypertension requires lipoprotein lipase. American Journal of Physiology. Endocrinology and Metabolism. 295: E705-13. PMID 18647880 DOI: 10.1152/ajpendo.90338.2008  0.321
2008 Park TS, Hu Y, Noh HL, Drosatos K, Okajima K, Buchanan J, Tuinei J, Homma S, Jiang XC, Abel ED, Goldberg IJ. Ceramide is a cardiotoxin in lipotoxic cardiomyopathy. Journal of Lipid Research. 49: 2101-12. PMID 18515784 DOI: 10.1194/jlr.M800147-JLR200  0.74
2008 Lee J, Goldberg IJ. Lipoproteini lipase-derived fatty acids: physiology and dysfunction. Current Hypertension Reports. 9: 462-6. PMID 18367009 DOI: 10.1007/s11906-007-0085-4  0.452
2008 Goldberg IJ, Hu Y, Noh HL, Wei J, Huggins LA, Rackmill MG, Hamai H, Reid BN, Blaner WS, Huang LS. Decreased lipoprotein clearance is responsible for increased cholesterol in LDL receptor knockout mice with streptozotocin-induced diabetes. Diabetes. 57: 1674-82. PMID 18346984 DOI: 10.2337/db08-0083  0.309
2007 Son NH, Park TS, Yamashita H, Yokoyama M, Huggins LA, Okajima K, Homma S, Szabolcs MJ, Huang LS, Goldberg IJ. Cardiomyocyte expression of PPARgamma leads to cardiac dysfunction in mice. The Journal of Clinical Investigation. 117: 2791-801. PMID 17823655 DOI: 10.1172/JCI30335  0.467
2007 Yokoyama M, Seo T, Park T, Yagyu H, Hu Y, Son NH, Augustus AS, Vikramadithyan RK, Ramakrishnan R, Pulawa LK, Eckel RH, Goldberg IJ. Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle. Journal of Lipid Research. 48: 646-55. PMID 17189607 DOI: 10.1194/Jlr.M600301-Jlr200  0.311
2007 Noh HL, Yamashita H, Goldberg IJ. Cardiac metabolism and mechanics are altered by genetic loss of lipoprotein triglyceride lipolysis. Cardiovascular Drugs and Therapy. 20: 441-4. PMID 17139480 DOI: 10.1007/s10557-006-0633-1  0.338
2006 Noh HL, Okajima K, Molkentin JD, Homma S, Homma S, Goldberg IJ. Acute lipoprotein lipase deletion in adult mice leads to dyslipidemia and cardiac dysfunction. American Journal of Physiology. Endocrinology and Metabolism. 291: E755-60. PMID 16684851 DOI: 10.1152/Ajpendo.00111.2006  0.388
2006 Augustus AS, Buchanan J, Park TS, Hirata K, Noh HL, Sun J, Homma S, D'armiento J, Abel ED, Goldberg IJ. Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction. The Journal of Biological Chemistry. 281: 8716-23. PMID 16410253 DOI: 10.1074/Jbc.M509890200  0.448
2005 Vikramadithyan RK, Hu Y, Noh HL, Liang CP, Hallam K, Tall AR, Ramasamy R, Goldberg IJ. Human aldose reductase expression accelerates diabetic atherosclerosis in transgenic mice. The Journal of Clinical Investigation. 115: 2434-43. PMID 16127462 DOI: 10.1172/Jci24819  0.359
2005 Pillutla P, Hwang YC, Augustus A, Yokoyama M, Yagyu H, Johnston TP, Kaneko M, Ramasamy R, Goldberg IJ. Perfusion of hearts with triglyceride-rich particles reproduces the metabolic abnormalities in lipotoxic cardiomyopathy. American Journal of Physiology. Endocrinology and Metabolism. 288: E1229-35. PMID 15701679 DOI: 10.1152/Ajpendo.00273.2004  0.44
2005 Vikramadithyan RK, Hirata K, Yagyu H, Hu Y, Augustus A, Homma S, Goldberg IJ. Peroxisome proliferator-activated receptor agonists modulate heart function in transgenic mice with lipotoxic cardiomyopathy. The Journal of Pharmacology and Experimental Therapeutics. 313: 586-93. PMID 15671204 DOI: 10.1124/jpet.104.080259  0.449
2004 Augustus A, Yagyu H, Haemmerle G, Bensadoun A, Vikramadithyan RK, Park SY, Kim JK, Zechner R, Goldberg IJ. Cardiac-specific knock-out of lipoprotein lipase alters plasma lipoprotein triglyceride metabolism and cardiac gene expression. The Journal of Biological Chemistry. 279: 25050-7. PMID 15028738 DOI: 10.1074/Jbc.M401028200  0.474
2004 Goldberg IJ, Isaacs A, Sehayek E, Breslow JL, Huang LS. Effects of streptozotocin-induced diabetes in apolipoprotein AI deficient mice. Atherosclerosis. 172: 47-53. PMID 14709356  0.314
2003 Yokoyama M, Yagyu H, Hu Y, Seo T, Hirata K, Homma S, Goldberg IJ. Apolipoprotein B production reduces lipotoxic cardiomyopathy: studies in heart-specific lipoprotein lipase transgenic mouse. The Journal of Biological Chemistry. 279: 4204-11. PMID 14634011 DOI: 10.1074/jbc.M311995200  0.478
2003 Yagyu H, Chen G, Yokoyama M, Hirata K, Augustus A, Kako Y, Seo T, Hu Y, Lutz EP, Merkel M, Bensadoun A, Homma S, Goldberg IJ. Lipoprotein lipase (LpL) on the surface of cardiomyocytes increases lipid uptake and produces a cardiomyopathy. The Journal of Clinical Investigation. 111: 419-26. PMID 12569168 DOI: 10.1172/Jci16751  0.408
2002 Augustus AS, Kako Y, Yagyu H, Goldberg IJ. Routes of FA delivery to cardiac muscle: modulation of lipoprotein lipolysis alters uptake of TG-derived FA. American Journal of Physiology. Endocrinology and Metabolism. 284: E331-9. PMID 12388125 DOI: 10.1152/ajpendo.00298.2002  0.415
2002 Kako Y, Massé M, Huang LS, Tall AR, Goldberg IJ. Lipoprotein lipase deficiency and CETP in streptozotocin-treated apoB-expressing mice. Journal of Lipid Research. 43: 872-7. PMID 12032161  0.337
2002 Yagyu H, Lutz EP, Kako Y, Marks S, Hu Y, Choi SY, Bensadoun A, Goldberg IJ. Very low density lipoprotein (VLDL) receptor-deficient mice have reduced lipoprotein lipase activity. Possible causes of hypertriglyceridemia and reduced body mass with VLDL receptor deficiency. The Journal of Biological Chemistry. 277: 10037-43. PMID 11790777 DOI: 10.1074/jbc.M109966200  0.336
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