Luis H. Barbeito - Publications

Affiliations: 
institut pasteur montevideo, Montevideo, Montevideo, Uruguay 
Area:
neurodegeneration

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Year Citation  Score
2023 Diniz F, Parmeggiani B, Brandão G, Ferreira BK, Teixeira MF, Streck EL, Olivera-Bravo S, Barbeito LH, Schuck PF, de Melo Reis RA, Ferreira GC. Dual Effect of Carnosine on ROS Formation in Rat Cultured Cortical Astrocytes. Molecular Neurobiology. PMID 38151612 DOI: 10.1007/s12035-023-03880-0  0.346
2021 Kovacs M, Alamón C, Maciel C, Varela V, Ibarburu S, Tarragó L, King PH, Si Y, Kwon Y, Hermine O, Barbeito L, Trias E. The pathogenic role of c-Kit+ mast cells in the spinal motor neuron-vascular niche in ALS. Acta Neuropathologica Communications. 9: 136. PMID 34389060 DOI: 10.1186/s40478-021-01241-3  0.414
2020 Ibarburu S, Kovacs M, Varela V, Rodríguez-Duarte J, Ingold M, Invernizzi P, Porcal W, Arévalo AP, Perelmuter K, Bollati-Fogolín M, Escande C, López GV, King P, Si Y, Kwon Y, ... ... Barbeito L, et al. A Nitroalkene Benzoic Acid Derivative Targets Reactive Microglia and Prolongs Survival in an Inherited Model of ALS via NF-κB Inhibition. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 33118131 DOI: 10.1007/s13311-020-00953-z  0.406
2019 Kovacs M, Trias E, Varela V, Ibarburu S, Beckman JS, Moura IC, Hermine O, King PH, Si Y, Kwon Y, Barbeito L. CD34 Identifies a Subset of Proliferating Microglial Cells Associated with Degenerating Motor Neurons in ALS. International Journal of Molecular Sciences. 20. PMID 31395804 DOI: 10.3390/ijms20163880  0.355
2019 Trias E, Beilby PR, Kovacs M, Ibarburu S, Varela V, Barreto-Núñez R, Bradford SC, Beckman JS, Barbeito L. Emergence of Microglia Bearing Senescence Markers During Paralysis Progression in a Rat Model of Inherited ALS. Frontiers in Aging Neuroscience. 11: 42. PMID 30873018 DOI: 10.3389/fnagi.2019.00042  0.446
2019 Martínez-Palma L, Miquel E, Lagos-Rodríguez V, Barbeito L, Cassina A, Cassina P. Mitochondrial Modulation by Dichloroacetate Reduces Toxicity of Aberrant Glial Cells and Gliosis in the SOD1G93A Rat Model of Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 16: 203-215. PMID 30159850 DOI: 10.1007/s13311-018-0659-7  0.347
2018 Trias E, Barbeito L, Yamanaka K. Phenotypic heterogeneity of astrocytes in motor neuron disease. Clinical & Experimental Neuroimmunology. 9: 225-234. PMID 30555538 DOI: 10.1111/Cen3.12476  0.333
2018 Trias E, King PH, Si Y, Kwon Y, Varela V, Ibarburu S, Kovacs M, Moura IC, Beckman JS, Hermine O, Barbeito L. Mast cells and neutrophils mediate peripheral motor pathway degeneration in ALS. Jci Insight. 3. PMID 30282815 DOI: 10.1172/jci.insight.123249  0.315
2017 Ibarburu S, Trias E, Lago N, Peluffo H, Barreto-Núñez R, Varela V, Beckman JS, Barbeito L. Focal Transplantation of Aberrant Glial Cells Carrying the SOD1G93A Mutation into Rat Spinal Cord Induces Extensive Gliosis. Neuroimmunomodulation. 24: 143-153. PMID 29131016 DOI: 10.1159/000480639  0.443
2017 Trias E, Ibarburu S, Barreto-Núñez R, Varela V, Moura IC, Dubreuil P, Hermine O, Beckman JS, Barbeito L. Evidence for mast cells contributing to neuromuscular pathology in an inherited model of ALS. Jci Insight. 2. PMID 29046475 DOI: 10.1172/jci.insight.95934  0.343
2017 Jiménez-Riani M, Díaz-Amarilla P, Isasi E, Casanova G, Barbeito L, Olivera-Bravo S. Ultrastructural features of aberrant glial cells isolated from the spinal cord of paralytic rats expressing the amyotrophic lateral sclerosis-linked SOD1G93A mutation. Cell and Tissue Research. 370: 391-401. PMID 28864831 DOI: 10.1007/s00441-017-2681-1  0.355
2017 Kim MJ, Vargas MR, Harlan BA, Killoy KM, Ball L, Comte-Walters S, Gooz M, Yamamoto Y, Beckman JS, Barbeito L, Pehar M. Nitration and glycation turn mature NGF into a toxic factor for motor neurons: a role for p75NTR and RAGE signaling in ALS. Antioxidants & Redox Signaling. PMID 28537420 DOI: 10.1089/ars.2016.6966  0.342
2016 Trias E, Ibarburu S, Barreto-Núñez R, Barbeito L. Significance of aberrant glial cell phenotypes in pathophysiology of amyotrophic lateral sclerosis. Neuroscience Letters. 636: 27-31. PMID 27473942 DOI: 10.1016/j.neulet.2016.07.052  0.435
2016 Trias E, Ibarburu S, Barreto-Núñez R, Babdor J, Maciel TT, Guillo M, Gros L, Dubreuil P, Díaz-Amarilla P, Cassina P, Martínez-Palma L, Moura IC, Beckman JS, Hermine O, Barbeito L. Post-paralysis tyrosine kinase inhibition with masitinib abrogates neuroinflammation and slows disease progression in inherited amyotrophic lateral sclerosis. Journal of Neuroinflammation. 13: 177. PMID 27400786 DOI: 10.1186/s12974-016-0620-9  0.408
2016 Diaz-Amarilla P, Miquel E, Trostchansky A, Trias E, Ferreira AM, Freeman BA, Cassina P, Barbeito L, Vargas MR, Rubbo H. Electrophilic nitro-fatty acids prevent astrocyte-mediated toxicity to motor neurons in a cell model of familial amyotrophic lateral sclerosis via nuclear factor erythroid 2-related factor activation. Free Radical Biology & Medicine. PMID 27012417 DOI: 10.1016/J.Freeradbiomed.2016.03.013  0.478
2015 Olivera-Bravo S, Barbeito L. A role of astrocytes in mediating postnatal neurodegeneration in Glutaric acidemia-type 1. Febs Letters. 589: 3492-7. PMID 26409499 DOI: 10.1016/j.febslet.2015.09.010  0.32
2015 Olivera-Bravo S, Ribeiro CA, Isasi E, Trías E, Leipnitz G, Díaz-Amarilla P, Woontner M, Beck C, Goodman SI, Souza D, Wajner M, Barbeito L. Striatal neuronal death mediated by astrocytes from the Gcdh-/- mouse model of glutaric acidemia type I. Human Molecular Genetics. 24: 4504-15. PMID 25968119 DOI: 10.1093/Hmg/Ddv175  0.386
2014 Miquel E, Cassina A, Martínez-Palma L, Souza JM, Bolatto C, Rodríguez-Bottero S, Logan A, Smith RA, Murphy MP, Barbeito L, Radi R, Cassina P. Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis. Free Radical Biology & Medicine. 70: 204-13. PMID 24582549 DOI: 10.1016/j.freeradbiomed.2014.02.019  0.39
2013 Trias E, Díaz-Amarilla P, Olivera-Bravo S, Isasi E, Drechsel DA, Lopez N, Bradford CS, Ireton KE, Beckman JS, Barbeito L. Phenotypic transition of microglia into astrocyte-like cells associated with disease onset in a model of inherited ALS. Frontiers in Cellular Neuroscience. 7: 274. PMID 24399933 DOI: 10.3389/Fncel.2013.00274  0.414
2013 Gandelman M, Levy M, Cassina P, Barbeito L, Beckman JS. P2X7 receptor-induced death of motor neurons by a peroxynitrite/FAS-dependent pathway. Journal of Neurochemistry. 126: 382-8. PMID 23646980 DOI: 10.1111/jnc.12286  0.793
2013 Seminotti B, Amaral AU, da Rosa MS, Fernandes CG, Leipnitz G, Olivera-Bravo S, Barbeito L, Ribeiro CA, de Souza DO, Woontner M, Goodman SI, Koeller DM, Wajner M. Disruption of brain redox homeostasis in glutaryl-CoA dehydrogenase deficient mice treated with high dietary lysine supplementation. Molecular Genetics and Metabolism. 108: 30-9. PMID 23218171 DOI: 10.1016/J.Ymgme.2012.11.001  0.313
2012 Miquel E, Cassina A, Martínez-Palma L, Bolatto C, Trías E, Gandelman M, Radi R, Barbeito L, Cassina P. Modulation of astrocytic mitochondrial function by dichloroacetate improves survival and motor performance in inherited amyotrophic lateral sclerosis. Plos One. 7: e34776. PMID 22509356 DOI: 10.1371/Journal.Pone.0034776  0.764
2012 Drechsel DA, Estévez AG, Barbeito L, Beckman JS. Nitric oxide-mediated oxidative damage and the progressive demise of motor neurons in ALS. Neurotoxicity Research. 22: 251-64. PMID 22488161 DOI: 10.1007/S12640-012-9322-Y  0.43
2012 Beilby PR, Drechse DA, Trias E, DiazAmarilla P, Barbeito L, Beckman JS. 135Neurotoxicity of Aberrant Astrocytes in a Rat Model of Familial Amyotrophic Lateral Sclerosis Free Radical Biology and Medicine. 53. DOI: 10.1016/J.Freeradbiomed.2012.10.190  0.301
2011 Díaz-Amarilla P, Olivera-Bravo S, Trias E, Cragnolini A, Martínez-Palma L, Cassina P, Beckman J, Barbeito L. Phenotypically aberrant astrocytes that promote motoneuron damage in a model of inherited amyotrophic lateral sclerosis Proceedings of the National Academy of Sciences of the United States of America. 108: 18126-18131. PMID 22010221 DOI: 10.1073/Pnas.1110689108  0.461
2011 Olivera-Bravo S, Fernández A, Sarlabós MN, Rosillo JC, Casanova G, Jiménez M, Barbeito L. Neonatal astrocyte damage is sufficient to trigger progressive striatal degeneration in a rat model of glutaric acidemia-I. Plos One. 6: e20831. PMID 21698251 DOI: 10.1371/journal.pone.0020831  0.374
2011 Diaz-Amarilla P, Trostchansky A, Cassina P, Ferreira A, Vargas MR, Freeman Ba, Barbeito L, Rubbo H. Nitro-Fatty Acids Activate Nrf2 in Spinal Cord Astrocytes Improving Motor Neurons Survival in a Model of Familiar Amyotrophic Lateral Sclerosis Free Radical Biology and Medicine. 51: S162-S163. DOI: 10.1016/J.Freeradbiomed.2011.10.228  0.399
2010 Garré JM, Retamal MA, Cassina P, Barbeito L, Bukauskas FF, Sáez JC, Bennett MV, Abudara V. FGF-1 induces ATP release from spinal astrocytes in culture and opens pannexin and connexin hemichannels. Proceedings of the National Academy of Sciences of the United States of America. 107: 22659-64. PMID 21148774 DOI: 10.1073/Pnas.1013793107  0.405
2010 Aebischer J, Cassina P, Otsmane B, Moumen A, Seilhean D, Meininger V, Barbeito L, Pettmann B, Raoul C. IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1. Cell Death and Differentiation. 18: 754-68. PMID 21072055 DOI: 10.1038/cdd.2010.143  0.306
2010 Gandelman M, Peluffo H, Beckman JS, Cassina P, Barbeito L. Extracellular ATP and the P2X7 receptor in astrocyte-mediated motor neuron death: implications for amyotrophic lateral sclerosis. Journal of Neuroinflammation. 7: 33. PMID 20534165 DOI: 10.1186/1742-2094-7-33  0.787
2010 Barbeito AG, Martinez-Palma L, Vargas MR, Pehar M, Mañay N, Beckman JS, Barbeito L, Cassina P. Lead exposure stimulates VEGF expression in the spinal cord and extends survival in a mouse model of ALS. Neurobiology of Disease. 37: 574-80. PMID 19914377 DOI: 10.1016/j.nbd.2009.11.007  0.342
2009 Sotelo-Silveira JR, Lepanto P, Elizondo V, Horjales S, Palacios F, Martinez-Palma L, Marin M, Beckman JS, Barbeito L. Axonal mitochondrial clusters containing mutant SOD1 in transgenic models of ALS. Antioxidants & Redox Signaling. 11: 1535-45. PMID 19344250 DOI: 10.1089/ars.2009.2614  0.393
2008 Olivera S, Fernandez A, Latini A, Rosillo JC, Casanova G, Wajner M, Cassina P, Barbeito L. Astrocytic proliferation and mitochondrial dysfunction induced by accumulated glutaric acidemia I (GAI) metabolites: possible implications for GAI pathogenesis. Neurobiology of Disease. 32: 528-34. PMID 18930146 DOI: 10.1016/j.nbd.2008.09.011  0.452
2008 Vargas MR, Pehar M, Díaz-Amarilla PJ, Beckman JS, Barbeito L. Transcriptional profile of primary astrocytes expressing ALS-linked mutant SOD1. Journal of Neuroscience Research. 86: 3515-25. PMID 18683239 DOI: 10.1002/jnr.21797  0.563
2008 Cassina P, Cassina A, Pehar M, Castellanos R, Gandelman M, de León A, Robinson KM, Mason RP, Beckman JS, Barbeito L, Radi R. Mitochondrial dysfunction in SOD1G93A-bearing astrocytes promotes motor neuron degeneration: prevention by mitochondrial-targeted antioxidants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4115-22. PMID 18417691 DOI: 10.1523/Jneurosci.5308-07.2008  0.779
2008 Dupuis L, Pehar M, Cassina P, Rene F, Castellanos R, Rouaux C, Gandelman M, Dimou L, Schwab ME, Loeffler JP, Barbeito L, Gonzalez de Aguilar JL. Nogo receptor antagonizes p75NTR-dependent motor neuron death. Proceedings of the National Academy of Sciences of the United States of America. 105: 740-5. PMID 18182498 DOI: 10.1073/Pnas.0703842105  0.783
2007 Pehar M, Vargas MR, Robinson KM, Cassina P, Díaz-Amarilla PJ, Hagen TM, Radi R, Barbeito L, Beckman JS. Mitochondrial superoxide production and nuclear factor erythroid 2-related factor 2 activation in p75 neurotrophin receptor-induced motor neuron apoptosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7777-85. PMID 17634371 DOI: 10.1523/Jneurosci.0823-07.2007  0.587
2006 Pehar M, Vargas MR, Robinson KM, Cassina P, England P, Beckman JS, Alzari PM, Barbeito L. Peroxynitrite transforms nerve growth factor into an apoptotic factor for motor neurons. Free Radical Biology & Medicine. 41: 1632-44. PMID 17145551 DOI: 10.1016/J.Freeradbiomed.2006.08.010  0.512
2006 Pehar M, Cassina P, Vargas MR, Xie Y, Beckman JS, Massa SM, Longo FM, Barbeito L. Modulation of p75-dependent motor neuron death by a small non-peptidyl mimetic of the neurotrophin loop 1 domain. The European Journal of Neuroscience. 24: 1575-80. PMID 17004921 DOI: 10.1111/j.1460-9568.2006.05040.x  0.63
2006 Sáez ET, Pehar M, Vargas MR, Barbeito L, Maccioni RB. Production of nerve growth factor by beta-amyloid-stimulated astrocytes induces p75NTR-dependent tau hyperphosphorylation in cultured hippocampal neurons. Journal of Neuroscience Research. 84: 1098-106. PMID 16862561 DOI: 10.1002/jnr.20996  0.497
2006 Vargas MR, Pehar M, Cassina P, Beckman JS, Barbeito L. Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis. Journal of Neurochemistry. 97: 687-96. PMID 16524372 DOI: 10.1111/j.1471-4159.2006.03742.x  0.632
2005 Pehar M, Vargas MR, Cassina P, Barbeito AG, Beckman JS, Barbeito L. Complexity of astrocyte-motor neuron interactions in amyotrophic lateral sclerosis. Neuro-Degenerative Diseases. 2: 139-46. PMID 16909019 DOI: 10.1159/000089619  0.595
2005 Vargas MR, Pehar M, Cassina P, Martínez-Palma L, Thompson JA, Beckman JS, Barbeito L. Fibroblast growth factor-1 induces heme oxygenase-1 via nuclear factor erythroid 2-related factor 2 (Nrf2) in spinal cord astrocytes: consequences for motor neuron survival. The Journal of Biological Chemistry. 280: 25571-9. PMID 15870071 DOI: 10.1074/jbc.M501920200  0.558
2005 Cassina P, Pehar M, Vargas MR, Castellanos R, Barbeito AG, Estévez AG, Thompson JA, Beckman JS, Barbeito L. Astrocyte activation by fibroblast growth factor-1 and motor neuron apoptosis: implications for amyotrophic lateral sclerosis. Journal of Neurochemistry. 93: 38-46. PMID 15773903 DOI: 10.1111/J.1471-4159.2004.02984.X  0.607
2005 Acarin L, Peluffo H, Barbeito L, Castellano B, González B. Astroglial Nitration after Postnatal Excitotoxic Damage: Correlation with Nitric Oxide Sources, Cytoskeletal, Apoptotic and Antioxidant Proteins Journal of Neurotrauma. 22: 189-200. PMID 15665612 DOI: 10.1089/Neu.2005.22.189  0.45
2004 Dupuis L, Gonzalez de Aguilar JL, Oudart H, de Tapia M, Barbeito L, Loeffler JP. Mitochondria in amyotrophic lateral sclerosis: a trigger and a target. Neuro-Degenerative Diseases. 1: 245-54. PMID 16908975 DOI: 10.1159/000085063  0.497
2004 Barbeito LH, Pehar M, Cassina P, Vargas MR, Peluffo H, Viera L, Estévez AG, Beckman JS. A role for astrocytes in motor neuron loss in amyotrophic lateral sclerosis. Brain Research. Brain Research Reviews. 47: 263-74. PMID 15572176 DOI: 10.1016/J.Brainresrev.2004.05.003  0.633
2004 Saez TE, Pehar M, Vargas M, Barbeito L, Maccioni RB. Astrocytic nitric oxide triggers tau hyperphosphorylation in hippocampal neurons. In Vivo (Athens, Greece). 18: 275-80. PMID 15341183  0.42
2004 Vargas MR, Pehar M, Cassina P, Estévez AG, Beckman JS, Barbeito L. Stimulation of nerve growth factor expression in astrocytes by peroxynitrite. In Vivo (Athens, Greece). 18: 269-74. PMID 15341182  0.436
2004 Sharif A, Renault F, Beuvon F, Castellanos R, Canton B, Barbeito L, Junier MP, Chneiweiss H. The expression of PEA-15 (phosphoprotein enriched in astrocytes of 15 kDa) defines subpopulations of astrocytes and neurons throughout the adult mouse brain. Neuroscience. 126: 263-75. PMID 15207344 DOI: 10.1016/j.neuroscience.2004.02.039  0.342
2004 Peluffo H, Shacka JJ, Ricart K, Bisig CG, Martìnez-Palma L, Pritsch O, Kamaid A, Eiserich JP, Crow JP, Barbeito L, Estèvez AG. Induction of motor neuron apoptosis by free 3-nitro-L-tyrosine. Journal of Neurochemistry. 89: 602-12. PMID 15086517 DOI: 10.1046/J.1471-4159.2004.02363.X  0.8
2004 Pehar M, Cassina P, Vargas MR, Castellanos R, Viera L, Beckman JS, Estévez AG, Barbeito L. Astrocytic production of nerve growth factor in motor neuron apoptosis: implications for amyotrophic lateral sclerosis. Journal of Neurochemistry. 89: 464-73. PMID 15056289 DOI: 10.1111/J.1471-4159.2004.02357.X  0.643
2003 Martinez-Palma L, Pehar M, Cassina P, Peluffo H, Castellanos R, Anesetti G, Beckman JS, Barbeito L. Involvement of nitric oxide on kainate-induced toxicity in oligodendrocyte precursors Neurotoxicity Research. 5: 399-406. PMID 14715442 DOI: 10.1007/Bf03033168  0.421
2003 Roth AD, Leisewitz AV, Jung JE, Cassina P, Barbeito L, Inestrosa NC, Bronfman M. PPAR gamma activators induce growth arrest and process extension in B12 oligodendrocyte-like cells and terminal differentiation of cultured oligodendrocytes. Journal of Neuroscience Research. 72: 425-35. PMID 12704804 DOI: 10.1002/Jnr.10596  0.332
2002 Pehar M, Martínez-Palma L, Peluffo H, Kamaid A, Cassina P, Barbeito L. Peroxynitrite-induced cytotoxicity in cultured astrocytes is associated with morphological changes and increased nitrotyrosine immunoreactivity. Neurotoxicity Research. 4: 87-93. PMID 12829407 DOI: 10.1080/10298420290015818  0.76
2002 Estévez AG, Kamaid A, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. Cyclic guanosine 5' monophosphate (GMP) prevents expression of neuronal nitric oxide synthase and apoptosis in motor neurons deprived of trophic factors in rats. Neuroscience Letters. 326: 201-5. PMID 12095656 DOI: 10.1016/S0304-3940(02)00341-5  0.79
2002 Cassina P, Peluffo H, Pehar M, Martinez-Palma L, Ressia A, Beckman JS, Estévez AG, Barbeito L. Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. Journal of Neuroscience Research. 67: 21-9. PMID 11754077 DOI: 10.1002/Jnr.10107  0.64
2001 Beckman JS, Estévez AG, Crow JP, Barbeito L. Superoxide dismutase and the death of motoneurons in ALS. Trends in Neurosciences. 24: S15-20. PMID 11881740 DOI: 10.1016/S0166-2236(00)01981-0  0.348
2001 Maccioni RB, Muñoz JP, Barbeito L. The molecular bases of Alzheimer's disease and other neurodegenerative disorders. Archives of Medical Research. 32: 367-81. PMID 11578751 DOI: 10.1016/S0188-4409(01)00316-2  0.402
2001 Cassina P, Peluffo H, Barbeito L. Adaptative responses of spinal astrocytes to oxidative stress. Progress in Brain Research. 132: 413-425. PMID 11545008 DOI: 10.1016/S0079-6123(01)32092-7  0.342
2000 Estévez AG, Sampson JB, Zhuang YX, Spear N, Richardson GJ, Crow JP, Tarpey MM, Barbeito L, Beckman JS. Liposome-delivered superoxide dismutase prevents nitric oxide-dependent motor neuron death induced by trophic factor withdrawal. Free Radical Biology & Medicine. 28: 437-46. PMID 10699756 DOI: 10.1016/S0891-5849(99)00261-0  0.555
1999 Estévez AG, Crow JP, Sampson JB, Reiter C, Zhuang Y, Richardson GJ, Tarpey MM, Barbeito L, Beckman JS. Induction of nitric oxide-dependent apoptosis in motor neurons by zinc-deficient superoxide dismutase. Science (New York, N.Y.). 286: 2498-500. PMID 10617463 DOI: 10.1126/Science.286.5449.2498  0.568
1999 Estévez AG, Spear N, Pelluffo H, Kamaid A, Barbeito L, Beckman JS. Examining apoptosis in cultured cells after exposure to nitric oxide and peroxynitrite. Methods in Enzymology. 301: 393-402. PMID 9919588 DOI: 10.1016/S0076-6879(99)01103-9  0.705
1998 Estévez AG, Spear N, Manuel SM, Barbeito L, Radi R, Beckman JS. Role of endogenous nitric oxide and peroxynitrite formation in the survival and death of motor neurons in culture. Progress in Brain Research. 118: 269-80. PMID 9932448 DOI: 10.1016/S0079-6123(08)63214-8  0.496
1998 Estévez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS. Nitric oxide and superoxide contribute to motor neuron apoptosis induced by trophic factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 923-31. PMID 9437014 DOI: 10.1523/Jneurosci.18-03-00923.1998  0.606
1998 Estévez AG, Spear N, Thompson JA, Cornwell TL, Radi R, Barbeito L, Beckman JS. Nitric Oxide-Dependent Production of cGMP Supports the Survival of Rat Embryonic Motor Neurons Cultured with Brain-Derived Neurotrophic Factor The Journal of Neuroscience. 18: 3708-3714. DOI: 10.1523/Jneurosci.18-10-03708.1998  0.593
1998 Estévez AG, Spear N, Manuel SM, Radi R, Henderson CE, Barbeito L, Beckman JS. Nitric Oxide and Superoxide Contribute to Motor Neuron Apoptosis Induced by Trophic Factor Deprivation The Journal of Neuroscience. 18: 923-931. DOI: 10.1523/JNEUROSCI.18-03-00923.1998  0.501
1997 Frizzo ME, Barbeito L. IA-type K+ channel blockers promote survival of cortical neurons in culture: involvement of L-type Ca2+ channels. Neuroreport. 8: 1803-6. PMID 9223055 DOI: 10.1097/00001756-199705260-00002  0.333
1996 Shin JT, Barbeito L, MacMillan-Crow LA, Beckman JS, Thompson JA. Acidic fibroblast growth factor enhances peroxynitrite-induced apoptosis in primary murine fibroblasts. Archives of Biochemistry and Biophysics. 335: 32-41. PMID 8914832 DOI: 10.1006/Abbi.1996.0479  0.384
1995 Estévez AG, Radi R, Barbeito L, Shin JT, Thompson JA, Beckman JS. Peroxynitrite-induced cytotoxicity in PC12 cells: evidence for an apoptotic mechanism differentially modulated by neurotrophic factors. Journal of Neurochemistry. 65: 1543-50. PMID 7561848 DOI: 10.1046/J.1471-4159.1995.65041543.X  0.375
1995 Estevez AG, Stutzmann JM, Barbeito L. Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures. European Journal of Pharmacology. 280: 47-53. PMID 7498253 DOI: 10.1016/0014-2999(95)00186-O  0.404
1991 Cheramy A, Kemel ML, Gauchy C, Desce JM, Galli T, Barbeito L, Glowinski J. Role of excitatory amino acids in the direct and indirect presynaptic regulation of dopamine release from nerve terminals of nigrostriatal dopaminergic neurons. Amino Acids. 1: 351-63. PMID 24194175 DOI: 10.1007/BF00814004  0.357
1990 Chéramy A, Barbeito L, Godeheu G, Desce JM, Pittaluga A, Galli T, Artaud F, Glowinski J. Respective contributions of neuronal activity and presynaptic mechanisms in the control of the in vivo release of dopamine. Journal of Neural Transmission. Supplementum. 29: 183-93. PMID 1972733 DOI: 10.1007/978-3-7091-9050-0_18  0.353
1989 Artaud F, Baruch P, Stutzmann JM, Saffroy M, Godeheu G, Barbeito L, Hervé D, Studler JM, Glowinski J, Chéramy A. Cholecystokinin: Corelease with dopamine from nigrostriatal neurons in the cat. The European Journal of Neuroscience. 1: 162-171. PMID 12106166 DOI: 10.1111/J.1460-9568.1989.Tb00784.X  0.303
1989 Barbeito L, Girault JA, Godeheu G, Pittaluga A, Glowinski J, Cheramy A. Activation of the bilateral corticostriatal glutamatergic projection by infusion of GABA into thalamic motor nuclei in the cat: an in vivo release study. Neuroscience. 28: 365-74. PMID 2564170 DOI: 10.1016/0306-4522(89)90183-8  0.353
1988 Glowinski J, Chéramy A, Romo R, Barbeito L. Presynaptic regulation of dopaminergic transmission in the striatum. Cellular and Molecular Neurobiology. 8: 7-17. PMID 2900072 DOI: 10.1007/BF00712906  0.318
Low-probability matches (unlikely to be authored by this person)
1991 Galli T, Godeheu G, Artaud F, Desce JM, Pittaluga A, Barbeito L, Glowsinki J, Chéramy A. Specific role of N-acetyl-aspartyl-glutamate in the in vivo regulation of dopamine release from dendrites and nerve terminals of nigrostriatal dopaminergic neurons in the cat. Neuroscience. 42: 19-28. PMID 1861773 DOI: 10.1016/0306-4522(91)90146-F  0.299
1986 Girault JA, Barbeito L, Spampinato U, Gozlan H, Glowinski J, Besson MJ. In vivo release of endogenous amino acids from the rat striatum: further evidence for a role of glutamate and aspartate in corticostriatal neurotransmission. Journal of Neurochemistry. 47: 98-106. PMID 2872275 DOI: 10.1111/J.1471-4159.1986.Tb02836.X  0.299
1997 Spear N, Estévez AG, Barbeito L, Beckman JS, Johnson GV. Nerve growth factor protects PC12 cells against peroxynitrite-induced apoptosis via a mechanism dependent on phosphatidylinositol 3-kinase. Journal of Neurochemistry. 69: 53-9. PMID 9202293 DOI: 10.1046/J.1471-4159.1997.69010053.X  0.293
2016 Villarreal A, Rosciszewski G, Murta V, Cadena V, Usach V, Dodes-Traian MM, Setton-Avruj P, Barbeito LH, Ramos AJ. Isolation and Characterization of Ischemia-Derived Astrocytes (IDAs) with Ability to Transactivate Quiescent Astrocytes. Frontiers in Cellular Neuroscience. 10: 139. PMID 27313509 DOI: 10.3389/fncel.2016.00139  0.291
1997 Peluffo H, Estevez A, Barbeito L, Stutzmann JM. Riluzole promotes survival of rat motoneurons in vitro by stimulating trophic activity produced by spinal astrocyte monolayers. Neuroscience Letters. 228: 207-11. PMID 9218644 DOI: 10.1016/S0304-3940(97)00384-4  0.291
2002 Brovia V, Costa A, Barbeito L. N-acetylsuccinimidylglutamate, a cyclic imide form of the peptide N-acetylaspartylglutamate, is present in low micromolar concentrations in murine and bovine CNS. Journal of Neurochemistry. 67: 382-388. PMID 8667017 DOI: 10.1046/J.1471-4159.1996.67010382.X  0.289
1988 Baruch P, Artaud F, Godeheu G, Barbeito L, Glowinski J, Chéramy A. Substance P and neurokinin A regulate by different mechanisms dopamine release from dendrites and nerve terminals of the nigrostriatal dopaminergic neurons. Neuroscience. 25: 889-98. PMID 2457187 DOI: 10.1016/0306-4522(88)90042-5  0.284
1990 Barbeito L, Chéramy A, Godeheu G, Desce JM, Glowinski J. Glutamate Receptors of a Quisqualate-Kainate Subtype are Involved in the Presynaptic Regulation of Dopamine Release in the Cat Caudate Nucleus in vivo. The European Journal of Neuroscience. 2: 304-311. PMID 12106037 DOI: 10.1111/J.1460-9568.1990.Tb00422.X  0.277
1992 Chéramy A, Barbeito L, Godeheu G, Glowinski J. Riluzole inhibits the release of glutamate in the caudate nucleus of the cat in vivo. Neuroscience Letters. 147: 209-12. PMID 1362807 DOI: 10.1016/0304-3940(92)90597-Z  0.273
2002 Beckman JS, Esétvez AG, Barbeito L, Crow JP. CCS knockout mice establish an alternative source of copper for SOD in ALS. Free Radical Biology & Medicine. 33: 1433-5. PMID 12419475 DOI: 10.1016/S0891-5849(02)01092-4  0.267
1990 Serval V, Barbeito L, Pittaluga A, Cheramy A, Lavielle S, Glowinski J. Competitive inhibition of N-acetylated-alpha-linked acidic dipeptidase activity by N-acetyl-L-aspartyl-beta-linked L-glutamate. Journal of Neurochemistry. 55: 39-46. PMID 2355230 DOI: 10.1111/J.1471-4159.1990.Tb08818.X  0.255
1988 Pittaluga A, Barbeito L, Serval V, Godeheu G, Artaud F, Glowinski J, Chéramy A. Depolarization-evoked release of N-acetyl-L-aspartyl-L-glutamate from rat brain synaptosomes. European Journal of Pharmacology. 158: 263-6. PMID 3150953 DOI: 10.1016/0014-2999(88)90076-3  0.253
2016 Williams JR, Trias E, Beilby PR, Lopez NI, Labut EM, Samuel Bradford C, Roberts BR, McAllum EJ, Crouch PJ, Rhoads TW, Pereira C, Son M, Elliott JL, Franco MC, Estévez AG, ... Barbeito L, et al. Copper delivery to the CNS by CuATSM effectively treats motor neuron disease in SOD(G93A) mice co-expressing the copper-chaperone-for-SOD. Neurobiology of Disease. PMID 26826269 DOI: 10.1016/J.Nbd.2016.01.020  0.25
2021 Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, et al. Reactive astrocyte nomenclature, definitions, and future directions. Nature Neuroscience. PMID 33589835 DOI: 10.1038/s41593-020-00783-4  0.239
2021 Martínez-Palma L, Miquel E, Lagos-Rodríguez V, Barbeito L, Cassina A, Cassina P. Correction to: Mitochondrial Modulation by Dichloroacetate Reduces Toxicity of Aberrant Glial Cells and Gliosis in the SOD1G93A Rat Model of Amyotrophic Lateral Sclerosis. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 17: 2089. PMID 32436178 DOI: 10.1007/s13311-020-00872-z  0.238
2012 Martínez-Palma L, Cassina A, Miquel E, Radi R, Barbeito L, Cassina et al⁎ P. Modulation of mitochondrial function and oxidative stress in highly toxic aberrrant-astrocytes Free Radical Biology and Medicine. 53: S178-S179. DOI: 10.1016/J.Freeradbiomed.2012.08.375  0.234
2015 Ghisoni K, Martins Rde P, Barbeito L, Latini A. Neopterin as a potential cytoprotective brain molecule. Journal of Psychiatric Research. 71: 134-9. PMID 26476490 DOI: 10.1016/j.jpsychires.2015.10.003  0.232
2019 Trias E, Kovacs M, King PH, Si Y, Kwon Y, Varela V, Ibarburu S, Moura IC, Hermine O, Beckman JS, Barbeito L. Schwann cells orchestrate peripheral nerve inflammation through the expression of CSF1, IL-34, and SCF in amyotrophic lateral sclerosis. Glia. PMID 31859421 DOI: 10.1002/glia.23768  0.208
2014 Beilby P, Trias E, Barreto R, Ibarburu S, Bradford S, Barbeito L, Beckman J. 19 - Glial Cell Senescence in Amyotrophic Lateral Sclerosis (ALS) Free Radical Biology and Medicine. 76. DOI: 10.1016/J.Freeradbiomed.2014.10.467  0.202
2018 Barbeito L. Astrocyte-based cell therapy: new hope for amyotrophic lateral sclerosis patients? Stem Cell Research & Therapy. 9: 241. PMID 30257722 DOI: 10.1186/s13287-018-1006-y  0.2
2014 Olivera-Bravo S, Isasi E, Fernández A, Rosillo JC, Jiménez M, Casanova G, Sarlabós MN, Barbeito L. White matter injury induced by perinatal exposure to glutaric acid. Neurotoxicity Research. 25: 381-91. PMID 24297153 DOI: 10.1007/s12640-013-9445-9  0.197
2018 Olivera-Bravo S, Seminotti B, Isasi E, Ribeiro CA, Leipnitz G, Woontner M, Goodman SI, Souza D, Barbeito L, Wajner M. Long Lasting High Lysine Diet Aggravates White Matter Injury in Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice. Molecular Neurobiology. PMID 29779173 DOI: 10.1007/S12035-018-1077-X  0.194
2005 Bendotti C, Cutrona MB, Cheroni C, Grignaschi G, Coco DL, Peviani M, Tortarolo M, Veglianese P, Zennaro E, Matsuoka M, Nishimoto I, Pehar M, Vargas MR, Cassina P, Barbeito AG, ... Barbeito L, et al. Author and Subject Index Neurodegenerative Diseases. 2: 232-232. DOI: 10.1159/000090900  0.183
2004 Kühn K, Zhu X, Fritzen S, Engels P, Ullmer C, Schwarz A, Burwinkel M, Valentine L, Kwon M, Herrling P, Dupuis L, Aguilar JGd, Maskri L, Oudart H, Schultz J, ... ... Barbeito L, et al. Subject Index Vol. 1, 2004 Neurodegenerative Diseases. 1: 324. DOI: 10.1159/000086267  0.176
2024 Barreto-Núñez R, Béland LC, Boutej H, Picher-Martel V, Dupré N, Barbeito L, Kriz J. Chronically activated microglia in ALS gradually lose their immune functions and develop unconventional proteome. Glia. PMID 38577970 DOI: 10.1002/glia.24531  0.174
2004 Kühn K, Zhu X, Fritzen S, Engels P, Ullmer C, Schwarz A, Burwinkel M, Valentine L, Kwon M, Herrling P, Dupuis L, Aguilar JGd, Maskri L, Oudart H, Schultz J, ... ... Barbeito L, et al. Contents Vol. 1, 2004 Neurodegenerative Diseases. 1: 325. DOI: 10.1159/000086268  0.173
2005 Barbeito L, Chun J, Binder LI, Neto VM, Perry G, Scazzochio C, Violini G. The end of a Chilean institute. Science (New York, N.Y.). 308: 792-3. PMID 15879193 DOI: 10.1126/Science.308.5723.792B  0.171
2017 Crispo M, Dos Santos-Neto PC, Vilariño M, Mulet AP, de León A, Barbeito L, Menchaca A. RAPID COMMUNICATION: Nerve growth factor influences cleavage rate and embryo development in sheep. Journal of Animal Science. 94: 4447-4451. PMID 27898841 DOI: 10.2527/jas.2016-0736  0.155
1987 Barbeito L, Fernández C, Silveira R, Dajas F. Evidences of a sympatho-adrenal dysfunction after lesion of the central noradrenergic pathways in rats. Journal of Neural Transmission. 67: 205-14. PMID 3806079 DOI: 10.1007/BF01243348  0.151
2016 Ghisoni K, Aguiar AS, de Oliveira PA, Matheus FC, Gabach L, Perez M, Carlini VP, Barbeito L, Mongeau R, Lanfumey L, Prediger RD, Latini A. Neopterin acts as an endogenous cognitive enhancer. Brain, Behavior, and Immunity. PMID 26916218 DOI: 10.1016/j.bbi.2016.02.019  0.148
1991 Siciliano J, Laborde C, Barbeito L. N-Acetyl-aspartyl-glutamate in the rat dorsal striatum: topographical distribution and effect of sensorimotor cortex lesions Neurochemistry International. 19: 593-599. DOI: 10.1016/0197-0186(91)90080-W  0.123
2020 Alamón C, Dávila B, García MF, Sánchez C, Kovacs M, Trias E, Barbeito L, Gabay M, Zeineh N, Gavish M, Teixidor F, Viñas C, Couto M, Cerecetto H. Sunitinib-Containing Carborane Pharmacophore with the Ability to Inhibit Tyrosine Kinases Receptors FLT3, KIT and PDGFR-β, Exhibits Powerful In Vivo Anti-Glioblastoma Activity. Cancers. 12. PMID 33218150 DOI: 10.3390/cancers12113423  0.115
1990 Barbeito L, Siciliano J, Dajas F. Depletion of the Ca(++)-dependent releasable pool of glutamate in striatal synaptosomes associated with dendrotoxin-induced potassium channel blockade. Journal of Neural Transmission. General Section. 80: 167-79. PMID 1970482 DOI: 10.1007/BF01245118  0.113
2014 Isasi E, Barbeito L, Olivera-Bravo S. Increased blood-brain barrier permeability and alterations in perivascular astrocytes and pericytes induced by intracisternal glutaric acid. Fluids and Barriers of the Cns. 11: 15. PMID 25077029 DOI: 10.1186/2045-8118-11-15  0.107
1988 Silveira R, Barbeito L, Dajas F. Behavioral and neurochemical effects of intraperitoneally injected dendrotoxin. Toxicon : Official Journal of the International Society On Toxinology. 26: 287-92. PMID 3394161 DOI: 10.1016/0041-0101(88)90219-X  0.094
2013 Brovia V, Ricciardi A, Barbeito L. N-Acetyl-aspartylglutamate (NAAG) in human cerebrospinal fluid: Determination by high performance liquid chromatography, and influence of biological variables. Amino Acids. 9: 175-84. PMID 24178817 DOI: 10.1007/BF00805838  0.091
2022 Duhalde Vega M, Olivera D, Gastão Davanzo G, Bertullo M, Noya V, Fabiano de Souza G, Primon Muraro S, Castro I, Arévalo AP, Crispo M, Galliussi G, Russo S, Charbonnier D, Rammauro F, Jeldres M, ... ... Barbeito L, et al. PD-1/PD-L1 blockade abrogates a dysfunctional innate-adaptive immune axis in critical β-coronavirus disease. Science Advances. 8: eabn6545. PMID 36129987 DOI: 10.1126/sciadv.abn6545  0.079
2012 Rodríguez-Ithurralde D, Silveira R, Barbeito L, Dajas F. Fasciculin, a powerful anticholinesterase polypeptide from Dendroaspis angusticeps venom. Neurochemistry International. 5: 267-74. PMID 20487949 DOI: 10.1016/0197-0186(83)90028-1  0.078
1985 Dajas F, Lista A, Barbeito L. High urinary norepinephrine excretion in major depressive disorders: effects of a new type of MAO inhibitor (Moclobemide, RO 11-1163). Acta Psychiatrica Scandinavica. 70: 432-7. PMID 6516893 DOI: 10.1111/j.1600-0447.1984.tb01231.x  0.061
1989 Monti JM, D'Angelo L, Jantos H, Barbeito L, Abó V. Effect of DSP-4, a noradrenergic neurotoxin, on sleep and wakefulness and sensitivity to drugs acting on adrenergic receptors in the rat. Sleep. 11: 370-7. PMID 2849796 DOI: 10.1093/SLEEP/11.4.370  0.052
2012 Rubbo⁎ H, Díaz P, Cassina P, Barbeito L, Ferreira A, Trostchansky A. Nitroarachidonic acid: Therapeutic potential in vascular inflammation and neurodegeneration Free Radical Biology and Medicine. 53: S184. DOI: 10.1016/j.freeradbiomed.2012.08.387  0.049
1983 Refsum E, Zivanovic S, Astrup C, Rorsman B, Hagnell O, Lanke J, Noël G, Jeanmart M, Reinhardt B, Constantinidis J, Bouras C, Guntern R, Taban CH, Tissot R, Egrise D, ... ... Barbeito L, et al. Heinrich Düker: Pioneer in Pharmacopsychology Neuropsychobiology. 10: 156-156. DOI: 10.1159/000118003  0.028
1986 Dajas F, Nin A, Barbeito L. Urinary norepinephrine excretion in panic and phobic disorders. Journal of Neural Transmission. 65: 75-81. PMID 3958707 DOI: 10.1007/BF01249613  0.024
2003 de Isusi AM, González E, Gayoso P, Gastelu-Iturri J, Barbeito L, Fernández R. [Diarrhea associated with Clostridium difficile: experience at a secondary hospital]. Medicina Clinica. 121: 331-3. PMID 14499069 DOI: 10.1016/s0025-7753(03)73939-6  0.02
1986 DAJAS F, BARBEITO L, CERVENANSKY C. An Association Between Norepinephrine-to-Epinephrine Ratio and Suicidal Ideation in Depression American Journal of Psychiatry. 143: 683-683. DOI: 10.1176/AJP.143.5.683  0.019
2003 Pazos R, Isusi A, Fernández R, Barbeito L, Bravo A, Cantón I, Gayoso P, Lebrato R. [Nosocomial diarrhea outbreak due to Clostridium difficile in a vascular surgery department]. Enfermedades Infecciosas Y Microbiologia Clinica. 21: 237-41. PMID 12732113 DOI: 10.1016/s0213-005x(03)72929-2  0.018
1984 Dajas F, Barbeito L, Martinez-Pesquera G, Lista A, Puppo D, Puppo-Touriz H. Plasma noradrenaline and clinical psychopathology in schizophrenia. A correlation analysis. Neuropsychobiology. 10: 70-4. PMID 6674828 DOI: 10.1159/000117988  0.012
2015 Arzt E, Savino W, Barbeito L. Editorial. Febs Letters. 589: 3329. PMID 26472322 DOI: 10.1016/j.febslet.2015.10.007  0.01
2013 Perone MJ, Velázquez G, Rojas de Arias A, Chamorro G, Coluchi N, Pirmez C, Savino W, Barbeito L, Arzt E. [First South american network of biomedical research. Education and biotechnology for health]. Medicina. 73: 75-7. PMID 23335711  0.01
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