Martin J. Lohse

Affiliations: 
1993- Pharmacology University of Wurzburg, Würzburg, Bayern, Germany 
Area:
Pharmacology; Receptors; Cell Signaling
Website:
http://www.pharmakologie.uni-wuerzburg.de/en/startpage/
Google:
"Martin Lohse"
Bio:

Born in Mainz, Germany, August 26th, 1956
Studied medicine and philosphoy at the universities of Göttingen, Germany, London, UK, and Paris, France.
State exam in medicine, Göttingen 1981; MD Göttingen 1981
Postdoc in pharmacology with Ulrich Schwabe, Bonn 1983, Heidelberg, Germany, 1983-1988
Research Associate and Assistant Professor with Robert J. Lefkowitz, Duke University 1988-1990
Group leader, Gene Center, Munich-Martinried, Germany, 1990-1993
Professor of Pharmacology, University of Würzburg, Germany, since 1993
Chairman, Rudolf Virchow Center, University of Würzburg, since 2001
Vice President for Research, University of Würzburg, Germany, 2009-2015
Vice President, Leopoldina National Academy of Sciences, Germany, since 2009

Mean distance: 12.82 (cluster 6)
 
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Publications

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Heuninck J, Perpina Viciano C, Işbilir A, et al. (2019) Context-dependent signalling of CXC chemokine receptor 4 (CXCR4) and atypical chemokine receptor 3 (ACKR3). Molecular Pharmacology
Grushevskyi EO, Kukaj T, Schmauder R, et al. (2019) Stepwise activation of a class C GPCR begins with millisecond dimer rearrangement. Proceedings of the National Academy of Sciences of the United States of America
Godbole A, Lyga S, Lohse MJ, et al. (2018) Publisher Correction: Internalized TSH receptors en route to the TGN induce local G-protein signaling and gene transcription. Nature Communications. 9: 5459
Picard LP, Schönegge AM, Lohse MJ, et al. (2018) Bioluminescence resonance energy transfer-based biosensors allow monitoring of ligand- and transducer-mediated GPCR conformational changes. Communications Biology. 1: 106
Schihada H, Vandenabeele S, Zabel U, et al. (2018) A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics. Communications Biology. 1: 105
Boivin-Jahns V, Uhland K, Holthoff HP, et al. (2018) Cyclopeptide COR-1 to treat beta1-adrenergic receptor antibody-induced heart failure. Plos One. 13: e0201160
Dolles D, Hoffmann M, Gunesch S, et al. (2018) Structure-Activity Relationships and Computational Investigations into the Development of Potent and Balanced Dual-Acting Butyrylcholinesterase Inhibitors and Human Cannabinoid Receptor 2 Ligands with Pro-Cognitive in Vivo Profiles. Journal of Medicinal Chemistry
Schönegge AM, Gallion J, Picard LP, et al. (2017) Evolutionary action and structural basis of the allosteric switch controlling β2AR functional selectivity. Nature Communications. 8: 2169
Andressen KW, Ulsund AH, Krobert KA, et al. (2017) Related GPCRs couple differently to Gs: preassociation between G protein and 5-HT7 serotonin receptor reveals movement of Gαs upon receptor activation. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology
Sungkaworn T, Jobin ML, Burnecki K, et al. (2017) Single-molecule imaging reveals receptor-G protein interactions at cell surface hot spots. Nature
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