Martin J. Lohse
Affiliations: | 1993- | Pharmacology | University of Würzburg, Würzburg, Bayern, Germany |
Area:
Pharmacology; Receptors; Cell SignalingWebsite:
http://www.pharmakologie.uni-wuerzburg.de/en/startpage/Google:
"Martin Lohse"Bio:
Born in Mainz, Germany, August 26th, 1956
Studied medicine and philosphoy at the universities of Göttingen, Germany, London, UK, and Paris, France.
State exam in medicine, Göttingen 1981; MD Göttingen 1981
Postdoc in pharmacology with Ulrich Schwabe, Bonn 1983, Heidelberg, Germany, 1983-1988
Research Associate and Assistant Professor with Robert J. Lefkowitz, Duke University 1988-1990
Group leader, Gene Center, Munich-Martinried, Germany, 1990-1993
Professor of Pharmacology, University of Würzburg, Germany, since 1993
Chairman, Rudolf Virchow Center, University of Würzburg, since 2001
Vice President for Research, University of Würzburg, Germany, 2009-2015
Vice President, Leopoldina National Academy of Sciences, Germany, since 2009
Mean distance: 12.82 (cluster 6) | S | N | B | C | P |
Parents
Sign in to add mentor| Otto D. Creutzfeldt | grad student | 1978-1980 | Max-Planck-Institut für biophysikalische Chemie |
| Ulrich Schwabe | post-doc | 1983-1988 | University of Heidelberg, Germany |
| Robert J. Lefkowitz | research scientist | Duke University / HHMI | |
| Ernst-Ludwig Winnacker | research scientist | 1990-1993 | University of Munich, Germany |
Children
Sign in to add trainee| Peter Hein | grad student | ||
| Ruthild G. Weber | grad student | 1986-1988 | Hannover Medical School |
| Susanne Pippig | grad student | 1991-1994 | Formycon AG |
| Stefan Engelhardt | grad student | 1991-2008 | Technical University of Munich |
| Viacheslav O. Nikolaev | grad student | 2003-2010 | University of Hamburg |
| Jean-Pierre Vilardaga | post-doc | 1999-2005 | University of Pittsburgh |
| Ursula Quitterer | post-doc | 1996-2006 | ETH/Uni Zurich |
| Moritz Bünemann | post-doc | 2000-2008 | University of Marburg |
| Lutz Hein | research scientist | 1996-2004 | University of Freiburg, Germany |
| Stefan Schulz | research scientist | 2006-2007 | University of Jena |
Collaborators
Sign in to add collaborator| Michel Bouvier | collaborator | Université de Montréal | |
| Brian K. Kobilka | collaborator | Stanford | |
| Jean-Philippe Pin | collaborator | Institute de Genomique Fonctionelle |
Publications
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| Nemec K, Schihada H, Kleinau G, et al. (2022) Functional modulation of PTH1R activation and signaling by RAMP2. Proceedings of the National Academy of Sciences of the United States of America. 119: e2122037119 |
| Rodríguez-Soacha DA, Steinmüller SAM, Işbilir A, et al. (2022) Development of an Indole-Amide-Based Photoswitchable Cannabinoid Receptor Subtype 1 (CBR) "Cis-On" Agonist. Acs Chemical Neuroscience. 13: 2410-2435 |
| Anton SE, Kayser C, Maiellaro I, et al. (2022) Receptor-associated independent cAMP nanodomains mediate spatiotemporal specificity of GPCR signaling. Cell. 185: 1130-1142.e11 |
| Kayser C, Lohse MJ, Bock A. (2022) Real-Time Measurements of Intracellular cAMP Gradients Using FRET-Based cAMP Nanorulers. Methods in Molecular Biology (Clifton, N.J.). 2483: 1-13 |
| Klenk C, Hommers L, Lohse MJ. (2022) Proteolytic Cleavage of the Extracellular Domain Affects Signaling of Parathyroid Hormone 1 Receptor. Frontiers in Endocrinology. 13: 839351 |
| Schihada H, Nemec K, Lohse MJ, et al. (2021) Bioluminescence in G Protein-Coupled Receptors Drug Screening Using Nanoluciferase and Halo-Tag Technology. Methods in Molecular Biology (Clifton, N.J.). 2268: 137-147 |
| Shahraki A, Işbilir A, Dogan B, et al. (2021) Structural and Functional Characterization of Allatostatin Receptor Type-C of , a Potential Target for Next-Generation Pest Control Agents. Journal of Chemical Information and Modeling |
| Işbilir A, Duan Sahbaz B, Tuncgenc G, et al. (2020) Pharmacological Characterization of the Stick Insect Allatostatin-C Receptor with Its Endogenous Agonist. Acs Omega. 5: 32183-32194 |
| Işbilir A, Möller J, Arimont M, et al. (2020) Advanced fluorescence microscopy reveals disruption of dynamic CXCR4 dimerization by subpocket-specific inverse agonists. Proceedings of the National Academy of Sciences of the United States of America |
| Gruteser N, Kohlhas V, Balfanz S, et al. (2020) Establishing a sensitive fluorescence-based quantification method for cyclic nucleotides. Bmc Biotechnology. 20: 47 |