| Year |
Citation |
Score |
| 2024 |
Sarott RC, Gourisankar S, Karim B, Nettles S, Yang H, Dwyer BG, Simanauskaite JM, Tse J, Abuzaid H, Krokhotin A, Zhang T, Hinshaw SM, Green MR, Crabtree GR, Gray NS. Relocalizing transcriptional kinases to activate apoptosis. Science (New York, N.Y.). 386: eadl5361. PMID 39361741 DOI: 10.1126/science.adl5361 |
0.799 |
|
| 2023 |
Gourisankar S, Krokhotin A, Wenderski W, Crabtree GR. Context-specific functions of chromatin remodellers in development and disease. Nature Reviews. Genetics. PMID 38001317 DOI: 10.1038/s41576-023-00666-x |
0.81 |
|
| 2023 |
Sarott R, Gourisankar S, Karim B, Nettles S, Yang H, Dwyer BG, Simanauskaite JM, Tse J, Abuzaid H, Krokhotin A, Zhang T, Hinshaw SM, Green MR, Crabtree GR, Gray NS. Borrowing Transcriptional Kinases to Activate Apoptosis. Biorxiv : the Preprint Server For Biology. PMID 37961702 DOI: 10.1101/2023.10.23.563687 |
0.803 |
|
| 2023 |
Gourisankar S, Krokhotin A, Ji W, Liu X, Chang CY, Kim SH, Li Z, Wenderski W, Simanauskaite JM, Yang H, Vogel H, Zhang T, Green MR, Gray NS, Crabtree GR. Author Correction: Rewiring cancer drivers to activate apoptosis. Nature. PMID 37596490 DOI: 10.1038/s41586-023-06543-1 |
0.761 |
|
| 2023 |
Gourisankar S, Krokhotin A, Ji W, Liu X, Chang CY, Kim SH, Li Z, Wenderski W, Simanauskaite JM, Yang H, Vogel H, Zhang T, Green MR, Gray NS, Crabtree GR. Rewiring cancer drivers to activate apoptosis. Nature. PMID 37495688 DOI: 10.1038/s41586-023-06348-2 |
0.814 |
|
| 2021 |
Chang CY, Shipony Z, Lin SG, Kuo A, Xiong X, Loh KM, Greenleaf WJ, Crabtree GR. Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma. Molecular Cell. PMID 34687603 DOI: 10.1016/j.molcel.2021.10.005 |
0.311 |
|
| 2021 |
Weber CM, Hafner A, Kirkland JG, Braun SMG, Stanton BZ, Boettiger AN, Crabtree GR. mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution. Nature Structural & Molecular Biology. 28: 501-511. PMID 34117481 DOI: 10.1038/s41594-021-00604-7 |
0.77 |
|
| 2021 |
Braun SMG, Petrova R, Tang J, Krokhotin A, Miller EL, Tang Y, Panagiotakos G, Crabtree GR. BAF subunit switching regulates chromatin accessibility to control cell cycle exit in the developing mammalian cortex. Genes & Development. PMID 33602870 DOI: 10.1101/gad.342345.120 |
0.323 |
|
| 2021 |
Lo YH, Kolahi KS, Du Y, Chang CY, Krokhotin A, Nair A, Sobba WD, Karlsson K, Jones SJ, Longacre TA, Mah AT, Tercan B, Sockell A, Xu H, Seoane JA, ... ... Crabtree GR, et al. A CRISPR/Cas9-engineered ARID1A-deficient human gastric cancer organoid model reveals essential and non-essential modes of oncogenic transformation. Cancer Discovery. PMID 33451982 DOI: 10.1158/2159-8290.CD-20-1109 |
0.536 |
|
| 2020 |
Sood S, Weber CM, Hodges HC, Krokhotin A, Shalizi A, Crabtree GR. CHD8 dosage regulates transcription in pluripotency and early murine neural differentiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 32839322 DOI: 10.1073/pnas.1921963117 |
0.798 |
|
| 2020 |
Chory EJ, Kirkland JG, Chang CY, D'Andrea VD, Gourisankar S, Dykhuizen EC, Crabtree GR. Chemical Inhibitors of a Selective SWI/SNF Function Synergize with ATR Inhibition in Cancer Cell Killing. Acs Chemical Biology. PMID 32369697 DOI: 10.1021/Acschembio.0C00312 |
0.79 |
|
| 2020 |
Wenderski W, Wang L, Krokhotin A, Walsh JJ, Li H, Shoji H, Ghosh S, George RD, Miller EL, Elias L, Gillespie MA, Son EY, Staahl BT, Baek ST, Stanley V, ... ... Crabtree GR, et al. Loss of the neural-specific BAF subunit ACTL6B relieves repression of early response genes and causes recessive autism. Proceedings of the National Academy of Sciences of the United States of America. PMID 32312822 DOI: 10.1073/Pnas.1908238117 |
0.806 |
|
| 2019 |
Seoane JA, Kirkland JG, Caswell-Jin JL, Crabtree GR, Curtis C. Chromatin regulators mediate anthracycline sensitivity in breast cancer. Nature Medicine. PMID 31700186 DOI: 10.1038/S41591-019-0638-5 |
0.723 |
|
| 2019 |
Chory EJ, Calarco JP, Hathaway NA, Bell O, Neel DS, Crabtree GR. Nucleosome Turnover Regulates Histone Methylation Patterns over the Genome. Molecular Cell. 73: 61-72.e3. PMID 30472189 DOI: 10.1016/J.Molcel.2018.10.028 |
0.78 |
|
| 2018 |
Marian CA, Stoszko M, Wang L, Leighty MW, de Crignis E, Maschinot CA, Gatchalian J, Carter BC, Chowdhury B, Hargreaves DC, Duvall JR, Crabtree GR, Mahmoudi T, Dykhuizen EC. Small Molecule Targeting of Specific BAF (mSWI/SNF) Complexes for HIV Latency Reversal. Cell Chemical Biology. PMID 30197195 DOI: 10.1016/J.Chembiol.2018.08.004 |
0.687 |
|
| 2018 |
Stanton BZ, Chory EJ, Crabtree GR. Chemically induced proximity in biology and medicine. Science (New York, N.Y.). 359. PMID 29590011 DOI: 10.1126/Science.Aao5902 |
0.767 |
|
| 2018 |
Hodges HC, Stanton BZ, Cermakova K, Chang CY, Miller EL, Kirkland JG, Ku WL, Veverka V, Zhao K, Crabtree GR. Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers. Nature Structural & Molecular Biology. 25: 61-72. PMID 29323272 DOI: 10.1038/s41594-017-0007-3 |
0.784 |
|
| 2017 |
Braun SMG, Kirkland JG, Chory EJ, Husmann D, Calarco JP, Crabtree GR. Rapid and reversible epigenome editing by endogenous chromatin regulators. Nature Communications. 8: 560. PMID 28916764 DOI: 10.1038/S41467-017-00644-Y |
0.819 |
|
| 2017 |
Stanton BZ, Hodges C, Crabtree GR, Zhao K. A General Non-Radioactive ATPase Assay for Chromatin Remodeling Complexes. Current Protocols in Chemical Biology. 9: 1-10. PMID 28253434 DOI: 10.1002/Cpch.16 |
0.561 |
|
| 2017 |
Miller EL, Hargreaves DC, Kadoch C, Chang CY, Calarco JP, Hodges C, Buenrostro JD, Cui K, Greenleaf WJ, Zhao K, Crabtree GR. TOP2 synergizes with BAF chromatin remodeling for both resolution and formation of facultative heterochromatin. Nature Structural & Molecular Biology. PMID 28250416 DOI: 10.1038/Nsmb.3384 |
0.802 |
|
| 2016 |
Kadoch C, Williams RT, Calarco JP, Miller EL, Weber CM, Braun SM, Pulice JL, Chory EJ, Crabtree GR. Dynamics of BAF-Polycomb complex opposition on heterochromatin in normal and oncogenic states. Nature Genetics. PMID 27941796 DOI: 10.1038/Ng.3734 |
0.818 |
|
| 2016 |
Stanton BZ, Hodges C, Calarco JP, Braun SM, Ku WL, Kadoch C, Zhao K, Crabtree GR. Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin. Nature Genetics. PMID 27941795 DOI: 10.1038/Ng.3735 |
0.718 |
|
| 2016 |
Hodges C, Kirkland JG, Crabtree GR. The Many Roles of BAF (mSWI/SNF) and PBAF Complexes in Cancer. Cold Spring Harbor Perspectives in Medicine. PMID 27413115 DOI: 10.1101/Cshperspect.A026930 |
0.75 |
|
| 2016 |
Panamarova M, Cox A, Wicher K, Butler R, Bulgakova N, Jeon S, Rosen B, Seong RH, Skarnes W, Crabtree G, Zernicka-Goetz M. BAF chromatin remodelling complex is an epigenetic regulator of lineage specification in the early mouse embryo. Development (Cambridge, England). PMID 26952987 DOI: 10.1242/Dev.131961 |
0.445 |
|
| 2015 |
Kadoch C, Crabtree GR. Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics. Science Advances. 1: e1500447. PMID 26601204 DOI: 10.1126/Sciadv.1500447 |
0.628 |
|
| 2015 |
Zhan X, Cao M, Yoo AS, Zhang Z, Chen L, Crabtree GR, Wu JI. Generation of BAF53b-Cre transgenic mice with pan-neuronal Cre activities. Genesis (New York, N.Y. : 2000). 53: 440-8. PMID 26077106 DOI: 10.1002/Dvg.22866 |
0.642 |
|
| 2014 |
Buscarlet M, Krasteva V, Ho L, Simon C, Hébert J, Wilhelm B, Crabtree GR, Sauvageau G, Thibault P, Lessard JA. Essential role of BRG, the ATPase subunit of BAF chromatin remodeling complexes, in leukemia maintenance. Blood. 123: 1720-8. PMID 24478402 DOI: 10.1182/Blood-2013-02-483495 |
0.32 |
|
| 2014 |
Crabtree G. Abstract SY24-03: Chromatin regulation in cancer Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Sy24-03 |
0.414 |
|
| 2014 |
Buscarlet M, Krasteva V, Ho L, Simon C, Hebert J, Wilhelm B, Crabtree G, Sauvageau G, Thibault P, Lessard J. An exchange of alternative ATPases within BAF complexes accompanies the transition from hemopoietic stem cell quiescence to proliferation Experimental Hematology. 42: S4. DOI: 10.1016/J.Exphem.2014.07.013 |
0.318 |
|
| 2013 |
Staahl BT, Crabtree GR. Creating a neural specific chromatin landscape by npBAF and nBAF complexes. Current Opinion in Neurobiology. 23: 903-13. PMID 24090879 DOI: 10.1016/j.conb.2013.09.003 |
0.77 |
|
| 2013 |
Tang J, Yoo AS, Crabtree GR. Reprogramming human fibroblasts to neurons by recapitulating an essential microRNA-chromatin switch. Current Opinion in Genetics & Development. 23: 591-8. PMID 24035011 DOI: 10.1016/J.Gde.2013.07.001 |
0.633 |
|
| 2013 |
Ninkovic J, Steiner-Mezzadri A, Jawerka M, Akinci U, Masserdotti G, Petricca S, Fischer J, von Holst A, Beckers J, Lie CD, Petrik D, Miller E, Tang J, Wu J, Lefebvre V, ... ... Crabtree G, et al. The BAF complex interacts with Pax6 in adult neural progenitors to establish a neurogenic cross-regulatory transcriptional network. Cell Stem Cell. 13: 403-18. PMID 23933087 DOI: 10.1016/J.Stem.2013.07.002 |
0.479 |
|
| 2013 |
Staahl BT, Tang J, Wu W, Sun A, Gitler AD, Yoo AS, Crabtree GR. Kinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 10348-61. PMID 23785148 DOI: 10.1523/Jneurosci.1258-13.2013 |
0.798 |
|
| 2013 |
Chesi A, Staahl BT, JoviÄić A, Couthouis J, Fasolino M, Raphael AR, Yamazaki T, Elias L, Polak M, Kelly C, Williams KL, Fifita JA, Maragakis NJ, Nicholson GA, King OD, ... ... Crabtree GR, et al. Exome sequencing to identify de novo mutations in sporadic ALS trios. Nature Neuroscience. 16: 851-5. PMID 23708140 DOI: 10.1038/Nn.3412 |
0.777 |
|
| 2013 |
Dykhuizen EC, Hargreaves DC, Miller EL, Cui K, Korshunov A, Kool M, Pfister S, Cho YJ, Zhao K, Crabtree GR. BAF complexes facilitate decatenation of DNA by topoisomerase IIα. Nature. 497: 624-7. PMID 23698369 DOI: 10.1038/Nature12146 |
0.781 |
|
| 2013 |
Kadoch C, Hargreaves DC, Hodges C, Elias L, Ho L, Ranish J, Crabtree GR. Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy. Nature Genetics. 45: 592-601. PMID 23644491 DOI: 10.1038/Ng.2628 |
0.791 |
|
| 2013 |
Kadoch C, Crabtree GR. Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma. Cell. 153: 71-85. PMID 23540691 DOI: 10.1016/J.Cell.2013.02.036 |
0.61 |
|
| 2013 |
Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, ... ... Crabtree GR, et al. The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory. Nature Neuroscience. 16: 552-61. PMID 23525042 DOI: 10.1038/Nn.3359 |
0.375 |
|
| 2013 |
Bao X, Tang J, Lopez-Pajares V, Tao S, Qu K, Crabtree GR, Khavari PA. ACTL6a enforces the epidermal progenitor state by suppressing SWI/SNF-dependent induction of KLF4. Cell Stem Cell. 12: 193-203. PMID 23395444 DOI: 10.1016/J.Stem.2012.12.014 |
0.595 |
|
| 2013 |
Sun AX, Crabtree GR, Yoo AS. MicroRNAs: regulators of neuronal fate. Current Opinion in Cell Biology. 25: 215-21. PMID 23374323 DOI: 10.1016/J.Ceb.2012.12.007 |
0.633 |
|
| 2013 |
Kadoch C, Crabtree GR. Reversing the oncogenic roles of misdirected chromatin remodeling: Mechanistic insights into the SS18-SSX fusion protein in synovial sarcoma. Journal of Clinical Oncology. 31: 10515-10515. DOI: 10.1200/Jco.2013.31.15_Suppl.10515 |
0.622 |
|
| 2013 |
Dykhuizen E, Hargreaves D, Miller E, Cui K, Korshunov A, Kool M, Pfister S, Cho Y, Zhao K, Crabtree G. Abstract PR08: mSWI/SNF (BAF) complexes facilitate decatentation of DNA by topoisomerase IIα Cancer Research. 73. DOI: 10.1158/1538-7445.Cec13-Pr08 |
0.597 |
|
| 2012 |
Dykhuizen EC, Carmody LC, Tolliday N, Crabtree GR, Palmer MA. Screening for inhibitors of an essential chromatin remodeler in mouse embryonic stem cells by monitoring transcriptional regulation. Journal of Biomolecular Screening. 17: 1221-30. PMID 22853929 DOI: 10.1177/1087057112455060 |
0.337 |
|
| 2012 |
Hathaway NA, Bell O, Hodges C, Miller EL, Neel DS, Crabtree GR. Dynamics and memory of heterochromatin in living cells. Cell. 149: 1447-60. PMID 22704655 DOI: 10.1016/J.Cell.2012.03.052 |
0.731 |
|
| 2012 |
Weeraratne SD, Archer T, Pugh TJ, Hargreaves D, Yu F, Kautzman A, Jones DTW, Jaeger N, Tamayo P, Mesirov JP, Pfister SM, Lichter P, Crabtree G, Meyerson M, Pomeroy SL, et al. Abstract 1313: Mutually exclusive somatic mutations in WNT pathway medulloblastomas reveal a critical interaction between DDX3X and SMARCA4 Cancer Research. 72: 1313-1313. DOI: 10.1158/1538-7445.Am2012-1313 |
0.353 |
|
| 2011 |
Yoo AS, Sun AX, Li L, Shcheglovitov A, Portmann T, Li Y, Lee-Messer C, Dolmetsch RE, Tsien RW, Crabtree GR. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature. 476: 228-31. PMID 21753754 DOI: 10.1038/Nature10323 |
0.586 |
|
| 2011 |
Hargreaves DC, Crabtree GR. ATP-dependent chromatin remodeling: genetics, genomics and mechanisms. Cell Research. 21: 396-420. PMID 21358755 DOI: 10.1038/cr.2011.32 |
0.74 |
|
| 2010 |
Shaw JP, Utz PJ, Durand DB, Toole JJ, Emmel EA, Crabtree GR. Identification of a putative regulator of early T cell activation genes. Science. 1988. 241: 202-205. Journal of Immunology (Baltimore, Md. : 1950). 185: 4972-5. PMID 20962265 DOI: 10.1126/Science.3260404 |
0.552 |
|
| 2010 |
Lessard JA, Crabtree GR. Chromatin regulatory mechanisms in pluripotency. Annual Review of Cell and Developmental Biology. 26: 503-32. PMID 20624054 DOI: 10.1146/annurev-cellbio-051809-102012 |
0.312 |
|
| 2009 |
Yoo AS, Staahl BT, Chen L, Crabtree GR. MicroRNA-mediated switching of chromatin-remodelling complexes in neural development. Nature. 460: 642-6. PMID 19561591 DOI: 10.1038/Nature08139 |
0.788 |
|
| 2009 |
Yoo AS, Crabtree GR. ATP-dependent chromatin remodeling in neural development. Current Opinion in Neurobiology. 19: 120-6. PMID 19442513 DOI: 10.1016/J.Conb.2009.04.006 |
0.658 |
|
| 2009 |
Ho L, Ronan JL, Wu J, Staahl BT, Chen L, Kuo A, Lessard J, Nesvizhskii AI, Ranish J, Crabtree GR. An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency. Proceedings of the National Academy of Sciences of the United States of America. 106: 5181-6. PMID 19279220 DOI: 10.1073/Pnas.0812889106 |
0.798 |
|
| 2009 |
Ho L, Jothi R, Ronan JL, Cui K, Zhao K, Crabtree GR. An embryonic stem cell chromatin remodeling complex, esBAF, is an essential component of the core pluripotency transcriptional network. Proceedings of the National Academy of Sciences of the United States of America. 106: 5187-91. PMID 19279218 DOI: 10.1073/Pnas.0812888106 |
0.576 |
|
| 2009 |
Kao SC, Wu H, Xie J, Chang CP, Ranish JA, Graef IA, Crabtree GR. Calcineurin/NFAT signaling is required for neuregulin-regulated Schwann cell differentiation. Science (New York, N.Y.). 323: 651-4. PMID 19179536 DOI: 10.1126/Science.1166562 |
0.672 |
|
| 2009 |
Lazarevic V, Zullo AJ, Schweitzer MN, Staton TL, Gallo EM, Crabtree GR, Glimcher LH. The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells. Nature Immunology. 10: 306-13. PMID 19169262 DOI: 10.1038/Ni.1696 |
0.673 |
|
| 2009 |
Wu JI, Lessard J, Crabtree GR. Understanding the words of chromatin regulation. Cell. 136: 200-6. PMID 19167321 DOI: 10.1016/J.Cell.2009.01.009 |
0.401 |
|
| 2008 |
Li DH, Winslow MM, Cao TM, Chen AH, Davis CR, Mellins ED, Utz PJ, Crabtree GR, Parnes JR. Modulation of peripheral B cell tolerance by CD72 in a murine model. Arthritis and Rheumatism. 58: 3192-204. PMID 18821699 DOI: 10.1002/Art.23812 |
0.669 |
|
| 2008 |
Gallo EM, Ho L, Winslow MM, Staton TL, Crabtree GR. Selective role of calcineurin in haematopoiesis and lymphopoiesis. Embo Reports. 9: 1141-8. PMID 18818667 DOI: 10.1038/Embor.2008.174 |
0.748 |
|
| 2008 |
Radermacher AN, Crabtree GR. Monster protein controls calcium entry and fights infection. Immunity. 28: 13-4. PMID 18199413 DOI: 10.1016/J.Immuni.2007.12.009 |
0.762 |
|
| 2007 |
Gallo EM, Winslow MM, Canté-Barrett K, Radermacher AN, Ho L, McGinnis L, Iritani B, Neilson JR, Crabtree GR. Calcineurin sets the bandwidth for discrimination of signals during thymocyte development. Nature. 450: 731-5. PMID 18046413 DOI: 10.1038/Nature06305 |
0.773 |
|
| 2007 |
Wu JI, Lessard J, Olave IA, Qiu Z, Ghosh A, Graef IA, Crabtree GR. Regulation of dendritic development by neuron-specific chromatin remodeling complexes. Neuron. 56: 94-108. PMID 17920018 DOI: 10.1016/J.Neuron.2007.08.021 |
0.455 |
|
| 2007 |
Wu H, Kao SC, Barrientos T, Baldwin SH, Olson EN, Crabtree GR, Zhou B, Chang CP. Down syndrome critical region-1 is a transcriptional target of nuclear factor of activated T cells-c1 within the endocardium during heart development. The Journal of Biological Chemistry. 282: 30673-9. PMID 17693409 DOI: 10.1074/Jbc.M703622200 |
0.673 |
|
| 2007 |
Lessard J, Wu JI, Ranish JA, Wan M, Winslow MM, Staahl BT, Wu H, Aebersold R, Graef IA, Crabtree GR. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron. 55: 201-15. PMID 17640523 DOI: 10.1016/J.Neuron.2007.06.019 |
0.801 |
|
| 2007 |
Stankunas K, Crabtree GR. Exploiting protein destruction for constructive use. Proceedings of the National Academy of Sciences of the United States of America. 104: 11511-2. PMID 17606901 DOI: 10.1073/Pnas.0704762104 |
0.697 |
|
| 2007 |
Wu JI, Crabtree GR, Crabtee GR. Cell signaling. Nuclear actin as choreographer of cell morphology and transcription. Science (New York, N.Y.). 316: 1710-1. PMID 17588921 DOI: 10.1126/science.1145014 |
0.402 |
|
| 2007 |
Canté-Barrett K, Winslow MM, Crabtree GR. Selective role of NFATc3 in positive selection of thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 179: 103-10. PMID 17579027 DOI: 10.4049/Jimmunol.179.1.103 |
0.606 |
|
| 2007 |
Stankunas K, Bayle JH, Havranek JJ, Wandless TJ, Baker D, Crabtree GR, Gestwicki JE. Rescue of degradation-prone mutants of the FK506-rapamycin binding (FRB) protein with chemical ligands. Chembiochem : a European Journal of Chemical Biology. 8: 1162-9. PMID 17525916 DOI: 10.1002/Cbic.200700087 |
0.673 |
|
| 2007 |
Sellmyer MA, Stankunas K, Briesewitz R, Crabtree GR, Wandless TJ. Engineering small molecule specificity in nearly identical cellular environments. Bioorganic & Medicinal Chemistry Letters. 17: 2703-5. PMID 17383876 DOI: 10.1016/J.Bmcl.2007.03.012 |
0.665 |
|
| 2007 |
Pan M, Winslow MM, Chen L, Kuo A, Felsher D, Crabtree GR. Enhanced NFATc1 nuclear occupancy causes T cell activation independent of CD28 costimulation. Journal of Immunology (Baltimore, Md. : 1950). 178: 4315-21. PMID 17371988 DOI: 10.4049/Jimmunol.178.7.4315 |
0.589 |
|
| 2007 |
Liu KJ, Arron JR, Stankunas K, Crabtree GR, Longaker MT. Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice. Nature. 446: 79-82. PMID 17293880 DOI: 10.1038/Nature05557 |
0.639 |
|
| 2007 |
Pan M, Winslow MM, Keum JS, Crabtree GR. Stringent control of NFATc1 nuclear occupancy is critical for maintaining balanced immune response Gene Therapy and Molecular Biology. 11: 171-176. |
0.518 |
|
| 2006 |
Davé V, Childs T, Xu Y, Ikegami M, Besnard V, Maeda Y, Wert SE, Neilson JR, Crabtree GR, Whitsett JA. Calcineurin/Nfat signaling is required for perinatal lung maturation and function. The Journal of Clinical Investigation. 116: 2597-609. PMID 16998587 DOI: 10.1172/Jci27331 |
0.568 |
|
| 2006 |
Heit JJ, Apelqvist AA, Gu X, Winslow MM, Neilson JR, Crabtree GR, Kim SK. Calcineurin/NFAT signalling regulates pancreatic beta-cell growth and function. Nature. 443: 345-9. PMID 16988714 DOI: 10.1038/Nature05097 |
0.713 |
|
| 2006 |
Ho L, Crabtree G. A Foxy tango with NFAT. Nature Immunology. 7: 906-8. PMID 16924253 DOI: 10.1038/ni0906-906 |
0.339 |
|
| 2006 |
Winslow MM, Pan M, Starbuck M, Gallo EM, Deng L, Karsenty G, Crabtree GR. Calcineurin/NFAT signaling in osteoblasts regulates bone mass. Developmental Cell. 10: 771-82. PMID 16740479 DOI: 10.1016/J.Devcel.2006.04.006 |
0.705 |
|
| 2006 |
Arron JR, Winslow MM, Polleri A, Chang CP, Wu H, Gao X, Neilson JR, Chen L, Heit JJ, Kim SK, Yamasaki N, Miyakawa T, Francke U, Graef IA, Crabtree GR. NFAT dysregulation by increased dosage of DSCR1 and DYRK1A on chromosome 21. Nature. 441: 595-600. PMID 16554754 DOI: 10.1038/Nature04678 |
0.789 |
|
| 2006 |
Winslow MM, Gallo EM, Neilson JR, Crabtree GR. The calcineurin phosphatase complex modulates immunogenic B cell responses. Immunity. 24: 141-52. PMID 16473827 DOI: 10.1016/J.Immuni.2005.12.013 |
0.786 |
|
| 2006 |
Canté-Barrett K, Gallo EM, Winslow MM, Crabtree GR. Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of bim [corrected]. Journal of Immunology (Baltimore, Md. : 1950). 176: 2299-306. PMID 16455986 DOI: 10.4049/Jimmunol.176.4.2299 |
0.745 |
|
| 2006 |
Bayle JH, Grimley JS, Stankunas K, Gestwicki JE, Wandless TJ, Crabtree GR. Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity. Chemistry & Biology. 13: 99-107. PMID 16426976 DOI: 10.1016/J.Chembiol.2005.10.017 |
0.674 |
|
| 2006 |
Gallo EM, Canté-Barrett K, Crabtree GR. Lymphocyte calcium signaling from membrane to nucleus. Nature Immunology. 7: 25-32. PMID 16357855 DOI: 10.1038/Ni1295 |
0.625 |
|
| 2006 |
Canté-Barrett K, Gallo EM, Winslow MM, Crabtree GR. Thymocyte negative selection is mediated by protein kinase C- and Ca2+-dependent transcriptional induction of Bim of cell death. The Journal of Immunology. 176: 3843.3-3843. DOI: 10.4049/jimmunol.176.6.3843-b |
0.633 |
|
| 2006 |
Liu KJ, Arron JR, Stankunas K, Crabtree GR. Signaling via GSK-3 is required during midline skeletogenesis Developmental Biology. 295: 434-435. DOI: 10.1016/J.Ydbio.2006.04.337 |
0.644 |
|
| 2006 |
Polleri A, Graef IA, Arron JR, Winslow MM, Kim SK, Miyakawa T, Francke U, Crabtree GR. Increased dosage of DSCR1 and DYRK1A on chromosome 21 destabilizes NFAT regulation and accounts for Down syndrome phenotypes Developmental Biology. 295: 324. DOI: 10.1016/J.Ydbio.2006.04.007 |
0.532 |
|
| 2005 |
Mammucari C, Tommasi di Vignano A, Sharov AA, Neilson J, Havrda MC, Roop DR, Botchkarev VA, Crabtree GR, Dotto GP. Integration of Notch 1 and calcineurin/NFAT signaling pathways in keratinocyte growth and differentiation control. Developmental Cell. 8: 665-76. PMID 15866158 DOI: 10.1016/J.Devcel.2005.02.016 |
0.615 |
|
| 2005 |
Winslow MM, Crabtree GR. Immunology. Decoding calcium signaling. Science (New York, N.Y.). 307: 56-7. PMID 15637261 DOI: 10.1126/Science.1108163 |
0.551 |
|
| 2004 |
Liston A, Lesage S, Gray DH, O'Reilly LA, Strasser A, Fahrer AM, Boyd RL, Wilson J, Baxter AG, Gallo EM, Crabtree GR, Peng K, Wilson SR, Goodnow CC. Generalized resistance to thymic deletion in the NOD mouse; a polygenic trait characterized by defective induction of Bim. Immunity. 21: 817-30. PMID 15589170 DOI: 10.1016/J.Immuni.2004.10.014 |
0.642 |
|
| 2004 |
Chang CP, Neilson JR, Bayle JH, Gestwicki JE, Kuo A, Stankunas K, Graef IA, Crabtree GR. A field of myocardial-endocardial NFAT signaling underlies heart valve morphogenesis. Cell. 118: 649-63. PMID 15339668 DOI: 10.1016/J.Cell.2004.08.010 |
0.774 |
|
| 2004 |
Parsons SA, Millay DP, Wilkins BJ, Bueno OF, Tsika GL, Neilson JR, Liberatore CM, Yutzey KE, Crabtree GR, Tsika RW, Molkentin JD. Genetic loss of calcineurin blocks mechanical overload-induced skeletal muscle fiber type switching but not hypertrophy. The Journal of Biological Chemistry. 279: 26192-200. PMID 15082723 DOI: 10.1074/Jbc.M313800200 |
0.573 |
|
| 2004 |
Aramburu J, Heitman J, Crabtree GR. Calcineurin: a central controller of signalling in eukaryotes. Embo Reports. 5: 343-8. PMID 15060569 DOI: 10.1038/Sj.Embor.7400133 |
0.32 |
|
| 2004 |
Chang CP, McDill BW, Neilson JR, Joist HE, Epstein JA, Crabtree GR, Chen F. Calcineurin is required in urinary tract mesenchyme for the development of the pyeloureteral peristaltic machinery. The Journal of Clinical Investigation. 113: 1051-8. PMID 15057312 DOI: 10.1172/Jci20049 |
0.722 |
|
| 2004 |
Neilson JR, Winslow MM, Hur EM, Crabtree GR. Calcineurin B1 is essential for positive but not negative selection during thymocyte development. Immunity. 20: 255-66. PMID 15030770 DOI: 10.1016/S1074-7613(04)00052-4 |
0.719 |
|
| 2003 |
Stankunas K, Bayle JH, Gestwicki JE, Lin YM, Wandless TJ, Crabtree GR. Conditional protein alleles using knockin mice and a chemical inducer of dimerization. Molecular Cell. 12: 1615-24. PMID 14690613 DOI: 10.1016/S1097-2765(03)00491-X |
0.683 |
|
| 2003 |
Chi TH, Wan M, Lee PP, Akashi K, Metzger D, Chambon P, Wilson CB, Crabtree GR. Sequential roles of Brg, the ATPase subunit of BAF chromatin remodeling complexes, in thymocyte development. Immunity. 19: 169-82. PMID 12932351 DOI: 10.1016/S1074-7613(03)00199-7 |
0.319 |
|
| 2003 |
Winslow MM, Neilson JR, Crabtree GR. Calcium signalling in lymphocytes. Current Opinion in Immunology. 15: 299-307. PMID 12787755 DOI: 10.1016/S0952-7915(03)00050-5 |
0.686 |
|
| 2003 |
Graef IA, Wang F, Charron F, Chen L, Neilson J, Tessier-Lavigne M, Crabtree GR. Neurotrophins and netrins require calcineurin/NFAT signaling to stimulate outgrowth of embryonic axons. Cell. 113: 657-70. PMID 12787506 DOI: 10.1016/S0092-8674(03)00390-8 |
0.56 |
|
| 2003 |
Chang CP, Chen L, Crabtree GR. Sonographic staging of the developmental status of mouse embryos in utero. Genesis (New York, N.Y. : 2000). 36: 7-11. PMID 12748962 DOI: 10.1002/Gene.10186 |
0.587 |
|
| 2003 |
Rando OJ, Chi TH, Crabtree GR. Second messenger control of chromatin remodeling. Nature Structural Biology. 10: 81-3. PMID 12555081 DOI: 10.1038/Nsb0203-81 |
0.597 |
|
| 2002 |
Olave I, Wang W, Xue Y, Kuo A, Crabtree GR. Identification of a polymorphic, neuron-specific chromatin remodeling complex. Genes & Development. 16: 2509-17. PMID 12368262 DOI: 10.1101/Gad.992102 |
0.44 |
|
| 2002 |
Diehn M, Alizadeh AA, Rando OJ, Liu CL, Stankunas K, Botstein D, Crabtree GR, Brown PO. Genomic expression programs and the integration of the CD28 costimulatory signal in T cell activation. Proceedings of the National Academy of Sciences of the United States of America. 99: 11796-801. PMID 12195013 DOI: 10.1073/Pnas.092284399 |
0.759 |
|
| 2002 |
Chi TH, Wan M, Zhao K, Taniuchi I, Chen L, Littman DR, Crabtree GR. Reciprocal regulation of CD4/CD8 expression by SWI/SNF-like BAF complexes. Nature. 418: 195-9. PMID 12110891 DOI: 10.1038/Nature00876 |
0.514 |
|
| 2002 |
Crabtree GR, Olson EN. NFAT signaling: choreographing the social lives of cells. Cell. 109: S67-79. PMID 11983154 DOI: 10.1016/S0092-8674(02)00699-2 |
0.307 |
|
| 2002 |
Rando OJ, Zhao K, Janmey P, Crabtree GR. Phosphatidylinositol-dependent actin filament binding by the SWI/SNF-like BAF chromatin remodeling complex. Proceedings of the National Academy of Sciences of the United States of America. 99: 2824-9. PMID 11880634 DOI: 10.1073/Pnas.032662899 |
0.669 |
|
| 2001 |
Biggar SR, Crabtree GR. Cell signaling can direct either binary or graded transcriptional responses. The Embo Journal. 20: 3167-76. PMID 11406593 DOI: 10.1093/Emboj/20.12.3167 |
0.81 |
|
| 2001 |
Neilson J, Stankunas K, Crabtree GR. Monitoring the duration of antigen-receptor occupancy by calcineurin/glycogen-synthase-kinase-3 control of NF-AT nuclear shuttling. Current Opinion in Immunology. 13: 346-50. PMID 11406367 DOI: 10.1016/S0952-7915(00)00225-9 |
0.745 |
|
| 2000 |
Bultman S, Gebuhr T, Yee D, La Mantia C, Nicholson J, Gilliam A, Randazzo F, Metzger D, Chambon P, Crabtree G, Magnuson T. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Molecular Cell. 6: 1287-95. PMID 11163203 DOI: 10.1016/S1097-2765(00)00127-1 |
0.42 |
|
| 2000 |
Biggar SR, Crabtree GR. Chemically regulated transcription factors reveal the persistence of repressor-resistant transcription after disrupting activator function. The Journal of Biological Chemistry. 275: 25381-90. PMID 10801867 DOI: 10.1074/Jbc.M002991200 |
0.813 |
|
| 2000 |
Rando OJ, Zhao K, Crabtree GR. Searching for a function for nuclear actin. Trends in Cell Biology. 10: 92-7. PMID 10675902 DOI: 10.1016/S0962-8924(99)01713-4 |
0.651 |
|
| 1999 |
Stankunas K, Graef IA, Neilson JR, Park SH, Crabtree GR. Signaling through calcium, calcineurin, and NF-AT in lymphocyte activation and development. Cold Spring Harbor Symposia On Quantitative Biology. 64: 505-16. PMID 11232327 DOI: 10.1101/Sqb.1999.64.505 |
0.742 |
|
| 1999 |
Graef IA, Mermelstein PG, Stankunas K, Neilson JR, Deisseroth K, Tsien RW, Crabtree GR. L-type calcium channels and GSK-3 regulate the activity of NF-ATc4 in hippocampal neurons. Nature. 401: 703-8. PMID 10537109 DOI: 10.1038/44378 |
0.765 |
|
| 1999 |
Biggar SR, Crabtree GR. Continuous and widespread roles for the Swi-Snf complex in transcription. The Embo Journal. 18: 2254-64. PMID 10205178 DOI: 10.1093/Emboj/18.8.2254 |
0.82 |
|
| 1998 |
Zhao K, Wang W, Rando OJ, Xue Y, Swiderek K, Kuo A, Crabtree GR. Rapid and phosphoinositol-dependent binding of the SWI/SNF-like BAF complex to chromatin after T lymphocyte receptor signaling. Cell. 95: 625-36. PMID 9845365 DOI: 10.1016/S0092-8674(00)81633-5 |
0.742 |
|
| 1998 |
Ring HZ, Vameghi-Meyers V, Wang W, Crabtree GR, Francke U. Five SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin (SMARC) genes are dispersed in the human genome. Genomics. 51: 140-3. PMID 9693044 DOI: 10.1006/Geno.1998.5343 |
0.353 |
|
| 1998 |
Wang W, Chi T, Xue Y, Zhou S, Kuo A, Crabtree GR. Architectural DNA binding by a high-mobility-group/kinesin-like subunit in mammalian SWI/SNF-related complexes. Proceedings of the National Academy of Sciences of the United States of America. 95: 492-8. PMID 9435219 DOI: 10.1073/Pnas.95.2.492 |
0.451 |
|
| 1997 |
Borchardt A, Liberles SD, Biggar SR, Crabtree GR, Schreiber SL. Small molecule-dependent genetic selection in stochastic nanodroplets as a means of detecting protein-ligand interactions on a large scale. Chemistry & Biology. 4: 961-8. PMID 9427663 DOI: 10.1016/S1074-5521(97)90304-5 |
0.783 |
|
| 1997 |
Freiberg RA, Spencer DM, Choate KA, Duh HJ, Schreiber SL, Crabtree GR, Khavari PA. Fas signal transduction triggers either proliferation or apoptosis in human fibroblasts. The Journal of Investigative Dermatology. 108: 215-9. PMID 9008237 DOI: 10.1111/1523-1747.Ep12334273 |
0.506 |
|
| 1996 |
Freiberg RA, Spencer DM, Choate KA, Peng PD, Schreiber SL, Crabtree GR, Khavari PA. Specific triggering of the Fas signal transduction pathway in normal human keratinocytes. The Journal of Biological Chemistry. 271: 31666-9. PMID 8940187 DOI: 10.1074/Jbc.271.49.31666 |
0.545 |
|
| 1996 |
Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. The Embo Journal. 15: 5370-82. PMID 8895581 |
0.807 |
|
| 1996 |
Wang W, Xue Y, Zhou S, Kuo A, Cairns BR, Crabtree GR. Diversity and specialization of mammalian SWI/SNF complexes. Genes & Development. 10: 2117-30. PMID 8804307 DOI: 10.1101/Gad.10.17.2117 |
0.471 |
|
| 1996 |
Ho SN, Biggar SR, Spencer DM, Schreiber SL, Crabtree GR. Dimeric ligands define a role for transcriptional activation domains in reinitiation. Nature. 382: 822-6. PMID 8752278 DOI: 10.1038/382822A0 |
0.812 |
|
| 1996 |
Wang W, Côté J, Xue Y, Zhou S, Khavari PA, Biggar SR, Muchardt C, Kalpana GV, Goff SP, Yaniv M, Workman JL, Crabtree GR. Purification and biochemical heterogeneity of the mammalian SWI-SNF complex. The Embo Journal. 15: 5370-5382. DOI: 10.1002/J.1460-2075.1996.Tb00921.X |
0.803 |
|
| 1995 |
Endrizzi JA, Cronk JD, Wang W, Crabtree GR, Alber T. Crystal structure of DCoH, a bifunctional, protein-binding transcriptional coactivator. Science (New York, N.Y.). 268: 556-9. PMID 7725101 DOI: 10.1126/Science.7725101 |
0.353 |
|
| 1994 |
Dunaief JL, Strober BE, Guha S, Khavari PA, Alin K, Luban J, Begemann M, Crabtree GR, Goff SP. The retinoblastoma protein and BRG1 form a complex and cooperate to induce cell cycle arrest. Cell. 79: 119-30. PMID 7923370 DOI: 10.1016/0092-8674(94)90405-7 |
0.585 |
|
| 1994 |
Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J. brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Developmental Biology. 161: 229-42. PMID 7904967 DOI: 10.1006/Dbio.1994.1023 |
0.582 |
|
| 1994 |
Kalpana GV, Marmon S, Wang W, Crabtree GR, Goff SP. Binding and stimulation of HIV-1 integrase by a human homolog of yeast transcription factor SNF5. Science (New York, N.Y.). 266: 2002-6. PMID 7801128 DOI: 10.1126/Science.7801128 |
0.409 |
|
| 1993 |
Khavari PA, Peterson CL, Tamkun JW, Mendel DB, Crabtree GR. BRG1 contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription. Nature. 366: 170-4. PMID 8232556 DOI: 10.1038/366170A0 |
0.577 |
|
| 1992 |
Kuo CJ, Conley PB, Chen L, Sladek FM, Darnell JE, Crabtree GR. A transcriptional hierarchy involved in mammalian cell-type specification. Nature. 355: 457-61. PMID 1734282 DOI: 10.1038/355457A0 |
0.511 |
|
| 1992 |
Kuo CJ, Chung J, Fiorentino DF, Flanagan WM, Blenis J, Crabtree GR. Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. Nature. 358: 70-3. PMID 1614535 DOI: 10.1038/358070A0 |
0.561 |
|
| 1992 |
Chung J, Kuo CJ, Crabtree GR, Blenis J. Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases. Cell. 69: 1227-36. PMID 1377606 DOI: 10.1016/0092-8674(92)90643-Q |
0.516 |
|
| 1991 |
Mendel DB, Khavari PA, Conley PB, Graves MK, Hansen LP, Admon A, Crabtree GR. Characterization of a cofactor that regulates dimerization of a mammalian homeodomain protein. Science (New York, N.Y.). 254: 1762-7. PMID 1763325 DOI: 10.1126/Science.1763325 |
0.535 |
|
| 1990 |
Kuo CJ, Conley PB, Hsieh CL, Francke U, Crabtree GR. Molecular cloning, functional expression, and chromosomal localization of mouse hepatocyte nuclear factor 1. Proceedings of the National Academy of Sciences of the United States of America. 87: 9838-42. PMID 2263635 DOI: 10.1073/Pnas.87.24.9838 |
0.531 |
|
| 1990 |
Baumhueter S, Mendel DB, Conley PB, Kuo CJ, Turk C, Graves MK, Edwards CA, Courtois G, Crabtree GR. HNF-1 shares three sequence motifs with the POU domain proteins and is identical to LF-B1 and APF. Genes & Development. 4: 372-9. PMID 1970973 DOI: 10.1101/gad.4.3.372 |
0.527 |
|
| 1981 |
Crabtree GR, Bloomfield CD, Smith KA, McKenna RW, Peterson BA, Hildebrandt L, Munck A. Glucocorticoid receptors and in vitro responses to glucocorticoid in acute nonlymphocytic leukemia. Cancer Research. 41: 4853-6. PMID 7296546 |
0.43 |
|
| 1981 |
Guyre PM, Crabtree GR, Bodwell JE, Munck A. MLC-conditioned media stimulate an increase in Fc receptors on human macrophages. Journal of Immunology (Baltimore, Md. : 1950). 126: 666-8. PMID 6450248 |
0.445 |
|
| 1980 |
Crabtree GR, Munck A, Smith KA. Glucocorticoids and lymphocytes. II. Cell cycle-dependent changes in glucocorticoid receptor content. Journal of Immunology (Baltimore, Md. : 1950). 125: 13-7. PMID 7381199 |
0.44 |
|
| 1980 |
Crabtree GR, Munck A, Smith KA. Glucocorticoids and lymphocytes. I. Increased glucocorticoid receptor levels in antigen-stimulated lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 124: 2430-5. PMID 7365260 |
0.456 |
|
| 1980 |
Crabtree GR, Gillis S, Smith KA, Munck A. Mechanisms of glucocorticoid-induced immunosuppression: inhibitory effects on expression of Fc receptors and production of T-cell growth factor. Journal of Steroid Biochemistry. 12: 445-9. PMID 6968381 DOI: 10.1016/0022-4731(80)90305-2 |
0.473 |
|
| 1979 |
Munck A, Crabtree GR, Smith KA. Glucocorticoid receptors and actions in rat thymocytes and immunologically stimulated human peripheral lymphocytes. Monographs On Endocrinology. 12: 341-55. PMID 492174 DOI: 10.1007/978-3-642-81265-1_19 |
0.454 |
|
| 1979 |
Crabtree GR, Munck A, Smith KA. Glucocorticoids inhibit expression of Fc receptors on the human granulocytic cell line HL-60. Nature. 279: 338-9. PMID 450087 DOI: 10.1038/279338A0 |
0.479 |
|
| 1979 |
Crabtree GR, Gillis S, Smith KA, Munck A. Glucocorticoids and immune responses. Arthritis and Rheumatism. 22: 1246-56. PMID 389249 DOI: 10.1002/art.1780221112 |
0.488 |
|
| 1978 |
Munck A, Crabtree GR, Smith KA. Effects and receptors of glucocorticoids in rat thymus cells and human peripheral lymphocytes. Journal of Toxicology and Environmental Health. 4: 409-25. PMID 351204 DOI: 10.1080/15287397809529668 |
0.485 |
|
| 1978 |
Crabtree GR, Smith KA, Munck A. Glucocorticoid receptors and sensitivity of isolated human leukemia and lymphoma cells. Cancer Research. 38: 4268-72. PMID 279402 |
0.43 |
|
| 1977 |
Smith KA, Crabtree GR, Kennedy SJ, Munck AU. Glucocorticoid receptors and glucocorticoid sensitivity of mitogen stimulated and unstimulated human lymphocytes. Nature. 267: 523-6. PMID 876370 DOI: 10.1038/267523a0 |
0.407 |
|
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