| Year |
Citation |
Score |
| 2016 |
Angeli PA, Spiegel AM, Haberman RP, Palacios AG, Rapp PR, Gallagher M. P4-276: Age-Dependent Hippocampal Changes in OCTODON DEGUS Alzheimer's & Dementia. 12: P1138-P1138. DOI: 10.1016/j.jalz.2016.07.018 |
0.692 |
|
| 2014 |
Spiegel AM, Sewal AS, Rapp PR. Epigenetic contributions to cognitive aging: disentangling mindspan and lifespan. Learning & Memory (Cold Spring Harbor, N.Y.). 21: 569-74. PMID 25227252 DOI: 10.1101/lm.033506.113 |
0.686 |
|
| 2014 |
Koh MT, Spiegel AM, Gallagher M. Age-associated changes in hippocampal-dependent cognition in Diversity Outbred mice. Hippocampus. 24: 1300-7. PMID 24909986 DOI: 10.1002/hipo.22311 |
0.711 |
|
| 2013 |
Spiegel AM, Koh MT, Vogt NM, Rapp PR, Gallagher M. Hilar interneuron vulnerability distinguishes aged rats with memory impairment. The Journal of Comparative Neurology. 521: 3508-23. PMID 23749483 DOI: 10.1002/cne.23367 |
0.657 |
|
| 2012 |
Stranahan AM, Jiam NT, Spiegel AM, Gallagher M. Aging reduces total neuron number in the dorsal component of the rodent prefrontal cortex. The Journal of Comparative Neurology. 520: 1318-26. PMID 22020730 DOI: 10.1002/Cne.22790 |
0.706 |
|
| 1983 |
Doppman JL, Krudy AG, Marx SJ, Saxe A, Schneider P, Norton JA, Spiegel AM, Downs RW, Schaaf M, Brennan ME, Schneider AB, Aurbach GD. Aspiration of enlarged parathyroid glands for parathyroid hormone assay. Radiology. 148: 31-5. PMID 6856859 DOI: 10.1148/Radiology.148.1.6856859 |
0.372 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2003 |
Crabtree JS, Scacheri PC, Ward JM, McNally SR, Swain GP, Montagna C, Hager JH, Hanahan D, Edlund H, Magnuson MA, Garrett-Beal L, Burns AL, Ried T, Chandrasekharappa SC, Marx SJ, ... Spiegel AM, et al. Of mice and MEN1: Insulinomas in a conditional mouse knockout. Molecular and Cellular Biology. 23: 6075-85. PMID 12917331 DOI: 10.1128/Mcb.23.17.6075-6085.2003 |
0.147 |
|
| 2002 |
Marx SJ, Simonds WF, Agarwal SK, Burns AL, Weinstein LS, Cochran C, Skarulis MC, Spiegel AM, Libutti SK, Alexander HR, Chen CC, Chang R, Chandrasekharappa SC, Collins FS. Hyperparathyroidism in hereditary syndromes: special expressions and special managements. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: N37-43. PMID 12412776 |
0.146 |
|
| 2015 |
Spiegel AM. Foreword Hypoparathyroidism. v-vi. DOI: 10.1007/978-88-470-5376-2 |
0.12 |
|
| 2005 |
Rosen JE, Costouros NG, Lorang D, Burns AL, Alexander HR, Skarulis MC, Cochran C, Pingpank JF, Marx SJ, Spiegel AM, Libutti SK. Gland size is associated with changes in gene expression profiles in sporadic parathyroid adenomas. Annals of Surgical Oncology. 12: 412-6. PMID 15915376 DOI: 10.1245/Aso.2005.03.103 |
0.119 |
|
| 2004 |
Scacheri PC, Kennedy AL, Chin K, Miller MT, Hodgson JG, Gray JW, Marx SJ, Spiegel AM, Collins FS. Pancreatic insulinomas in multiple endocrine neoplasia, type I knockout mice can develop in the absence of chromosome instability or microsatellite instability. Cancer Research. 64: 7039-44. PMID 15466197 DOI: 10.1158/0008-5472.Can-04-1648 |
0.116 |
|
| 1998 |
Doppman JL, Skarulis MC, Chang R, Alexander HR, Bartlett D, Libutti SK, Marx SJ, Spiegel AM. Hypocalcemic stimulation and nonselective venous sampling for localizing parathyroid adenomas: work in progress. Radiology. 208: 145-51. PMID 9646806 DOI: 10.1148/Radiology.208.1.9646806 |
0.114 |
|
| 2007 |
Wettschureck N, Lee E, Libutti SK, Offermanns S, Robey PG, Spiegel AM. Parathyroid-specific double knockout of Gq and G11 alpha-subunits leads to a phenotype resembling germline knockout of the extracellular Ca2+ -sensing receptor. Molecular Endocrinology (Baltimore, Md.). 21: 274-80. PMID 16988000 DOI: 10.1210/Me.2006-0110 |
0.108 |
|
| 2004 |
Scacheri PC, Crabtree JS, Kennedy AL, Swain GP, Ward JM, Marx SJ, Spiegel AM, Collins FS. Homozygous loss of menin is well tolerated in liver, a tissue not affected in MEN1. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 872-7. PMID 15672591 DOI: 10.1007/S00335-004-2395-Z |
0.102 |
|
| 2003 |
Libutti SK, Crabtree JS, Lorang D, Burns AL, Mazzanti C, Hewitt SM, O'Connor S, Ward JM, Emmert-Buck MR, Remaley A, Miller M, Turner E, Alexander HR, Arnold A, Marx SJ, ... ... Spiegel AM, et al. Parathyroid gland-specific deletion of the mouse Men1 gene results in parathyroid neoplasia and hypercalcemic hyperparathyroidism. Cancer Research. 63: 8022-8. PMID 14633735 |
0.101 |
|
| 2000 |
Bianco P, Riminucci M, Majolagbe A, Kuznetsov SA, Collins MT, Mankani MH, Corsi A, Bone HG, Wientroub S, Spiegel AM, Fisher LW, Robey PG. Mutations of the GNAS1 gene, stromal cell dysfunction, and osteomalacic changes in non-McCune-Albright fibrous dysplasia of bone. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 15: 120-8. PMID 10646121 DOI: 10.1359/Jbmr.2000.15.1.120 |
0.099 |
|
| 1986 |
Weinstock RS, Wright HN, Spiegel AM, Levine MA, Moses AM. Olfactory dysfunction in humans with deficient guanine nucleotide-binding protein. Nature. 322: 635-6. PMID 3018580 DOI: 10.1038/322635A0 |
0.097 |
|
| 1982 |
Marx SJ, Attie MF, Spiegel AM, Levine MA, Lasker RD, Fox M. An association between neonatal severe primary hyperparathyroidism and familial hypocalciuric hypercalcemia in three kindreds. The New England Journal of Medicine. 306: 257-64. PMID 7054696 DOI: 10.1056/Nejm198202043060502 |
0.096 |
|
| 1978 |
Marx SJ, Spiegel AM, Brown EM, Windeck R, Gardner DG, Downs RW, Attie M, Aurbach GD. Circulating parathyroid hormone activity: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 1190-7. PMID 233692 DOI: 10.1210/Jcem-47-6-1190 |
0.093 |
|
| 1983 |
Spiegel AM, Saxe AW, Deftos LJ, Brennan MF. Humoral hypercalcemia caused by a rat Leydig-cell tumor is associated with suppressed parathyroid hormone secretion and increased urinary cAMP excretion. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 15: 299-304. PMID 6307850 DOI: 10.1055/S-2007-1018700 |
0.093 |
|
| 2001 |
Crabtree JS, Scacheri PC, Ward JM, Garrett-Beal L, Emmert-Buck MR, Edgemon KA, Lorang D, Libutti SK, Chandrasekharappa SC, Marx SJ, Spiegel AM, Collins FS. A mouse model of multiple endocrine neoplasia, type 1, develops multiple endocrine tumors. Proceedings of the National Academy of Sciences of the United States of America. 98: 1118-23. PMID 11158604 DOI: 10.1073/Pnas.98.3.1118 |
0.092 |
|
| 2007 |
Spiegel AM. Inherited endocrine diseases involving G proteins and G protein-coupled receptors. Endocrine Development. 11: 133-44. PMID 17986833 DOI: 10.1159/0000111069 |
0.091 |
|
| 1997 |
De Luca F, Ray K, Mancilla EE, Fan GF, Winer KK, Gore P, Spiegel AM, Baron J. Sporadic hypoparathyroidism caused by de Novo gain-of-function mutations of the Ca(2+)-sensing receptor. The Journal of Clinical Endocrinology and Metabolism. 82: 2710-5. PMID 9253358 DOI: 10.1210/Jcem.82.8.4166 |
0.091 |
|
| 2001 |
Scacheri PC, Crabtree JS, Novotny EA, Garrett-Beal L, Chen A, Edgemon KA, Marx SJ, Spiegel AM, Chandrasekharappa SC, Collins FS. Bidirectional transcriptional activity of PGK-neomycin and unexpected embryonic lethality in heterozygote chimeric knockout mice. Genesis (New York, N.Y. : 2000). 30: 259-63. PMID 11536432 DOI: 10.1002/Gene.1072 |
0.09 |
|
| 2004 |
Agarwal SK, Lee Burns A, Sukhodolets KE, Kennedy PA, Obungu VH, Hickman AB, Mullendore ME, Whitten I, Skarulis MC, Simonds WF, Mateo C, Crabtree JS, Scacheri PC, Ji Y, Novotny EA, ... ... Spiegel AM, et al. Molecular pathology of the MEN1 gene. Annals of the New York Academy of Sciences. 1014: 189-98. PMID 15153434 DOI: 10.1196/Annals.1294.020 |
0.089 |
|
| 1977 |
Bilezikian JP, Spiegel AM, Gammon DE, Aurbach GD. The role of guanyl nucleotides in the expression on of catecholamine-responsive adenylate cyclase during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 786-95. PMID 197394 |
0.087 |
|
| 2000 |
Knapp JI, Heppner C, Hickman AB, Burns AL, Chandrasekharappa SC, Collins FS, Marx SJ, Spiegel AM, Agarwal SK. Identification and characterization of JunD missense mutants that lack menin binding. Oncogene. 19: 4706-12. PMID 11032020 DOI: 10.1038/Sj.Onc.1203832 |
0.087 |
|
| 1984 |
Heinsimer JA, Davies AO, Downs RW, Levine MA, Spiegel AM, Drezner MK, De Lean A, Wreggett KA, Caron MG, Lefkowitz RJ. Impaired formation of beta-adrenergic receptor-nucleotide regulatory protein complexes in pseudohypoparathyroidism. The Journal of Clinical Investigation. 73: 1335-43. PMID 6325502 DOI: 10.1172/Jci111336 |
0.085 |
|
| 1987 |
Milligan G, Streaty RA, Gierschik P, Spiegel AM, Klee WA. Development of opiate receptors and GTP-binding regulatory proteins in neonatal rat brain. The Journal of Biological Chemistry. 262: 8626-30. PMID 3036816 |
0.085 |
|
| 2006 |
Scacheri PC, Davis S, Odom DT, Crawford GE, Perkins S, Halawi MJ, Agarwal SK, Marx SJ, Spiegel AM, Meltzer PS, Collins FS. Genome-wide analysis of menin binding provides insights into MEN1 tumorigenesis. Plos Genetics. 2: e51. PMID 16604156 DOI: 10.1371/Journal.Pgen.0020051 |
0.084 |
|
| 2001 |
Reyes-Cruz G, Hu J, Goldsmith PK, Steinbach PJ, Spiegel AM. Human Ca(2+) receptor extracellular domain. Analysis of function of lobe I loop deletion mutants. The Journal of Biological Chemistry. 276: 32145-51. PMID 11399760 DOI: 10.1074/Jbc.M102977200 |
0.084 |
|
| 2006 |
Hu J, Jiang J, Costanzi S, Thomas C, Yang W, Feyen JH, Jacobson KA, Spiegel AM. A missense mutation in the seven-transmembrane domain of the human Ca2+ receptor converts a negative allosteric modulator into a positive allosteric modulator. The Journal of Biological Chemistry. 281: 21558-65. PMID 16735501 DOI: 10.1074/Jbc.M603682200 |
0.084 |
|
| 2004 |
Hu J, Mora S, Weber G, Zamproni I, Proverbio MC, Spiegel AM. Autosomal dominant hypocalcemia in monozygotic twins caused by a de novo germline mutation near the amino-terminus of the human calcium receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 19: 578-86. PMID 15005845 DOI: 10.1359/Jbmr.040106 |
0.084 |
|
| 1998 |
Bianco P, Kuznetsov SA, Riminucci M, Fisher LW, Spiegel AM, Robey PG. Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells. The Journal of Clinical Investigation. 101: 1737-44. PMID 9541505 DOI: 10.1172/Jci2361 |
0.083 |
|
| 1990 |
Spiegel AM. Receptor-effector coupling by G-proteins: implications for neuronal plasticity. Progress in Brain Research. 86: 269-76. PMID 1965054 DOI: 10.1016/S0079-6123(08)63183-0 |
0.083 |
|
| 2007 |
Ozawa A, Agarwal SK, Mateo CM, Burns AL, Rice TS, Kennedy PA, Quigley CM, Simonds WF, Weinstein LS, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. The parathyroid/pituitary variant of multiple endocrine neoplasia type 1 usually has causes other than p27Kip1 mutations. The Journal of Clinical Endocrinology and Metabolism. 92: 1948-51. PMID 17299066 DOI: 10.1210/Jc.2006-2563 |
0.083 |
|
| 1981 |
Spiegel AM, Downs RW, Levine MA, Singer MJ, Krawietz W, Marx SJ, Woodard CJ, Reen SA, Aurbach GD. The role of guanine nucleotides in regulation of adenylate cyclase activity. Recent Progress in Hormone Research. 37: 635-65. PMID 7280358 DOI: 10.1016/B978-0-12-571137-1.50018-9 |
0.079 |
|
| 1994 |
Abou-Samra AB, Goldsmith PK, Xie LY, Jüppner H, Spiegel AM, Segre GV. Down-regulation of parathyroid (PTH)/PTH-related peptide receptor immunoreactivity and PTH binding in opossum kidney cells by PTH and dexamethasone. Endocrinology. 135: 2588-94. PMID 7988447 DOI: 10.1210/endo.135.6.7988447 |
0.079 |
|
| 1987 |
Gawler D, Milligan G, Spiegel AM, Unson CG, Houslay MD. Abolition of the expression of inhibitory guanine nucleotide regulatory protein Gi activity in diabetes. Nature. 327: 229-32. PMID 3106832 DOI: 10.1038/327229A0 |
0.079 |
|
| 2004 |
Spiegel AM, Weinstein LS. Inherited diseases involving g proteins and g protein-coupled receptors. Annual Review of Medicine. 55: 27-39. PMID 14746508 DOI: 10.1146/Annurev.Med.55.091902.103843 |
0.078 |
|
| 1999 |
Spiegel AM. Hormone resistance caused by mutations in G proteins and G protein-coupled receptors. Journal of Pediatric Endocrinology & Metabolism : Jpem. 12: 303-9. PMID 10698594 |
0.078 |
|
| 2000 |
Goebel SU, Peghini PL, Goldsmith PK, Spiegel AM, Gibril F, Raffeld M, Jensen RT, Serrano J. Expression of the calcium-sensing receptor in gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 4131-7. PMID 11095444 DOI: 10.1210/Jcem.85.11.6963 |
0.078 |
|
| 1997 |
Spiegel AM. The molecular basis of disorders caused by defects in G proteins. Hormone Research. 47: 89-96. PMID 9050946 DOI: 10.1159/000185441 |
0.077 |
|
| 2005 |
Agarwal SK, Kennedy PA, Scacheri PC, Novotny EA, Hickman AB, Cerrato A, Rice TS, Moore JB, Rao S, Ji Y, Mateo C, Libutti SK, Oliver B, Chandrasekharappa SC, Burns AL, ... ... Spiegel AM, et al. Menin molecular interactions: insights into normal functions and tumorigenesis. Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Mã©Tabolisme. 37: 369-74. PMID 16001329 DOI: 10.1055/S-2005-870139 |
0.077 |
|
| 1985 |
Downs RW, Sekura RD, Levine MA, Spiegel AM. The inhibitory adenylate cyclase coupling protein in pseudohypoparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 61: 351-4. PMID 2989320 DOI: 10.1210/Jcem-61-2-351 |
0.076 |
|
| 1990 |
Weinstein LS, Kats I, Spiegel AM, Carter AD. Characterization of the promoter of the human Gi2 alpha-subunit gene. Molecular Endocrinology (Baltimore, Md.). 4: 958-64. PMID 2126599 DOI: 10.1210/Mend-4-7-958 |
0.076 |
|
| 1978 |
Spiegel AM, Marx SJ, Brennan MF, Brown EM, Koehler JO, Aurbach GD. Urinary cAMP excretion during surgery: an index of successful parathyroidectomy in patients with primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 47: 537-42. PMID 233674 DOI: 10.1210/Jcem-47-3-537 |
0.076 |
|
| 1977 |
Bilezikian JP, Spiegel AM, Brown EM, Aurbach GD. Identification and persistence of beta adrenergic receptors during maturation of the rat reticulocyte. Molecular Pharmacology. 13: 775-85. PMID 197393 |
0.076 |
|
| 1992 |
Meinkoth JL, Goldsmith PK, Spiegel AM, Feramisco JR, Burrow GN. Inhibition of thyrotropin-induced DNA synthesis in thyroid follicular cells by microinjection of an antibody to the stimulatory G protein of adenylate cyclase, Gs. The Journal of Biological Chemistry. 267: 13239-45. PMID 1377681 |
0.075 |
|
| 1997 |
Fan G, Goldsmith PK, Collins R, Dunn CK, Krapcho KJ, Rogers KV, Spiegel AM. N-linked glycosylation of the human Ca2+ receptor is essential for its expression at the cell surface. Endocrinology. 138: 1916-22. PMID 9112387 DOI: 10.1210/Endo.138.5.5131 |
0.075 |
|
| 2002 |
Hu J, Mora S, Colussi G, Proverbio MC, Jones KA, Bolzoni L, De Ferrari ME, Civati G, Spiegel AM. Autosomal dominant hypocalcemia caused by a novel mutation in the loop 2 region of the human calcium receptor extracellular domain. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 17: 1461-9. PMID 12162500 DOI: 10.1359/Jbmr.2002.17.8.1461 |
0.075 |
|
| 1981 |
Spiegel AM, Downs RW. Guanine nucleotides: key regulators of hormone receptor-adenylate cyclase interaction. Endocrine Reviews. 2: 275-305. PMID 6115747 DOI: 10.1210/Edrv-2-3-275 |
0.075 |
|
| 1992 |
Spiegel AM, Shenker A, Weinstein LS. Receptor-effector coupling by G proteins: implications for normal and abnormal signal transduction. Endocrine Reviews. 13: 536-65. PMID 1425488 DOI: 10.1210/Edrv-13-3-536 |
0.074 |
|
| 1984 |
Spiegel AM, Rudorfer MV, Marx SJ, Linnoila M. The effect of short term lithium administration on suppressibility of parathyroid hormone secretion by calcium in vivo. The Journal of Clinical Endocrinology and Metabolism. 59: 354-7. PMID 6330156 DOI: 10.1210/Jcem-59-2-354 |
0.074 |
|
| 2000 |
Spiegel AM. G protein defects in signal transduction. Hormone Research. 53: 17-22. PMID 10971097 DOI: 10.1159/000023526 |
0.074 |
|
| 1997 |
Chandrasekharappa SC, Guru SC, Manickam P, Olufemi SE, Collins FS, Emmert-Buck MR, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Crabtree JS, Wang Y, Roe BA, Weisemann J, Boguski MS, ... Spiegel AM, et al. Positional cloning of the gene for multiple endocrine neoplasia-type 1. Science (New York, N.Y.). 276: 404-7. PMID 9103196 DOI: 10.1126/Science.276.5311.404 |
0.074 |
|
| 1980 |
Marx SJ, Spiegel AM, Sharp ME, Brown EM, Gardner DG, Downs RW, Attie MF, Stock JL. Adenosine 3',5'-monophosphate response to parathyroid hormone: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 50: 546-8. PMID 6244324 DOI: 10.1210/Jcem-50-3-546 |
0.073 |
|
| 2001 |
Guru SC, Prasad NB, Shin EJ, Hemavathy K, Lu J, Ip YT, Agarwal SK, Marx SJ, Spiegel AM, Collins FS, Oliver B, Chandrasekharappa SC. Characterization of a MEN1 ortholog from Drosophila melanogaster. Gene. 263: 31-8. PMID 11223240 DOI: 10.1016/S0378-1119(00)00562-X |
0.073 |
|
| 1998 |
Fan GF, Ray K, Zhao XM, Goldsmith PK, Spiegel AM. Mutational analysis of the cysteines in the extracellular domain of the human Ca2+ receptor: effects on cell surface expression, dimerization and signal transduction. Febs Letters. 436: 353-6. PMID 9801147 DOI: 10.1016/S0014-5793(98)01165-X |
0.073 |
|
| 2015 |
Hannan FM, Walls GV, Babinsky VN, Nesbit MA, Kallay E, Hough TA, Fraser WD, Cox RD, Hu J, Spiegel AM, Thakker RV. The calcilytic agent NPS 2143 rectifies hypocalcemia in a mouse model with an activating calcium-sensing-receptor (CaSR) mutation: relevance to autosomal dominant hypocalcemia type 1 (ADH1). Endocrinology. en20151269. PMID 26052899 DOI: 10.1210/en.2015-1269 |
0.073 |
|
| 1999 |
Goldsmith PK, Fan GF, Ray K, Shiloach J, McPhie P, Rogers KV, Spiegel AM. Expression, purification, and biochemical characterization of the amino-terminal extracellular domain of the human calcium receptor. The Journal of Biological Chemistry. 274: 11303-9. PMID 10196220 DOI: 10.1074/Jbc.274.16.11303 |
0.073 |
|
| 1998 |
Emmert-Buck MR, Debelenko LV, Agarwal S, Kester MB, Manickam P, Zhuang Z, Guru SC, Olufemi SE, Burns AL, Chandrasekharappa SC, Lubensky IA, Liotta LA, Skarulis MC, Spiegel AM, Marx SJ, et al. 11q13 allelotype analysis in 27 northern American MEN1 kindreds identifies two distinct founder chromosomes. Molecular Genetics and Metabolism. 63: 151-5. PMID 9562970 DOI: 10.1006/Mgme.1997.2649 |
0.072 |
|
| 2013 |
Spiegel AM. G proteins--the disease spectrum expands. The New England Journal of Medicine. 368: 2515-6. PMID 23802519 DOI: 10.1056/Nejme1304751 |
0.072 |
|
| 2000 |
Hauache OM, Hu J, Ray K, Spiegel AM. Functional interactions between the extracellular domain and the seven-transmembrane domain in Ca2+ receptor activation. Endocrine. 13: 63-70. PMID 11051048 DOI: 10.1385/Endo:13:1:63 |
0.072 |
|
| 2009 |
Shen HC, He M, Powell A, Adem A, Lorang D, Heller C, Grover AC, Ylaya K, Hewitt SM, Marx SJ, Spiegel AM, Libutti SK. Recapitulation of pancreatic neuroendocrine tumors in human multiple endocrine neoplasia type I syndrome via Pdx1-directed inactivation of Men1. Cancer Research. 69: 1858-66. PMID 19208834 DOI: 10.1158/0008-5472.Can-08-3662 |
0.072 |
|
| 1987 |
Senogles SE, Benovic JL, Amlaiky N, Unson C, Milligan G, Vinitsky R, Spiegel AM, Caron MG. The D2-dopamine receptor of anterior pituitary is functionally associated with a pertussis toxin-sensitive guanine nucleotide binding protein. The Journal of Biological Chemistry. 262: 4860-7. PMID 3104325 |
0.072 |
|
| 1996 |
Hermouet S, Aznavoorian S, Spiegel AM. In vitro and in vivo growth inhibition of murine melanoma K-1735 cell by a dominant negative mutant alpha subunit of the Gi2 protein. Cellular Signalling. 8: 159-66. PMID 8736698 DOI: 10.1016/0898-6568(95)02049-7 |
0.072 |
|
| 1981 |
Krudy AG, Doppman JL, Marx SJ, Spiegel AM, Aurbach G, Brennan MF. Failure of ablation of a mediastinal parathyroid adenoma by repeated contrast staining. Radiology. 140: 63-5. PMID 6166026 DOI: 10.1148/Radiology.140.1.6166026 |
0.072 |
|
| 2007 |
Agarwal SK, Impey S, McWeeney S, Scacheri PC, Collins FS, Goodman RH, Spiegel AM, Marx SJ. Distribution of menin-occupied regions in chromatin specifies a broad role of menin in transcriptional regulation. Neoplasia (New York, N.Y.). 9: 101-7. PMID 17356705 DOI: 10.1593/Neo.06706 |
0.071 |
|
| 1988 |
Darling GE, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. Prospective analysis of intraoperative and postoperative urinary cyclic adenosine 3',5'-monophosphate levels to predict outcome of patients undergoing reoperations for primary hyperparathyroidism. Surgery. 104: 1128-36. PMID 2848325 |
0.071 |
|
| 2005 |
Hu J, McLarnon SJ, Mora S, Jiang J, Thomas C, Jacobson KA, Spiegel AM. A region in the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+. The Journal of Biological Chemistry. 280: 5113-20. PMID 15591042 DOI: 10.1074/Jbc.M413403200 |
0.071 |
|
| 2016 |
Babinsky VN, Hannan FM, Gorvin CM, Howles SA, Nesbit MA, Rust N, Hanyaloglu AC, Hu J, Spiegel AM, Thakker RV. Allosteric Modulation of the Calcium-Sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein alpha-11 Mutations causing Hypercalcemic and Hypocalcemic Disorders. The Journal of Biological Chemistry. PMID 26994139 DOI: 10.1074/jbc.M115.696401 |
0.071 |
|
| 1978 |
Marx SJ, Spiegel AM, Brown EM, Koehler JO, Gardner DG, Brennan MF, Aurbach GD. Divalent cation metabolism. Familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The American Journal of Medicine. 65: 235-42. PMID 686009 DOI: 10.1016/0002-9343(78)90814-8 |
0.071 |
|
| 2007 |
Hu J, Spiegel AM. Structure and function of the human calcium-sensing receptor: insights from natural and engineered mutations and allosteric modulators. Journal of Cellular and Molecular Medicine. 11: 908-22. PMID 17979873 DOI: 10.1111/j.1582-4934.2007.00096.x |
0.07 |
|
| 1992 |
LaMorte VJ, Goldsmith PK, Spiegel AM, Meinkoth JL, Feramisco JR. Inhibition of DNA synthesis in living cells by microinjection of Gi2 antibodies. The Journal of Biological Chemistry. 267: 691-4. PMID 1730660 |
0.07 |
|
| 1992 |
Doherty GM, Doppman JL, Miller DL, Gee MS, Marx SJ, Spiegel AM, Aurbach GD, Pass HI, Brennan MF, Norton JA. Results of a multidisciplinary strategy for management of mediastinal parathyroid adenoma as a cause of persistent primary hyperparathyroidism. Annals of Surgery. 215: 101-6. PMID 1546895 DOI: 10.1097/00000658-199202000-00002 |
0.07 |
|
| 1998 |
Guru SC, Goldsmith PK, Burns AL, Marx SJ, Spiegel AM, Collins FS, Chandrasekharappa SC. Menin, the product of the MEN1 gene, is a nuclear protein. Proceedings of the National Academy of Sciences of the United States of America. 95: 1630-4. PMID 9465067 DOI: 10.1073/Pnas.95.4.1630 |
0.07 |
|
| 1995 |
Spiegel AM. G protein gene knockout hits the gut. Nature Medicine. 1: 522-4. PMID 7585115 DOI: 10.1038/Nm0695-522 |
0.07 |
|
| 1996 |
Spiegel AM. Defects in G protein-coupled signal transduction in human disease. Annual Review of Physiology. 58: 143-70. PMID 8815789 DOI: 10.1146/annurev.ph.58.030196.001043 |
0.07 |
|
| 2001 |
Heppner C, Bilimoria KY, Agarwal SK, Kester M, Whitty LJ, Guru SC, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ, Burns AL. The tumor suppressor protein menin interacts with NF-kappaB proteins and inhibits NF-kappaB-mediated transactivation. Oncogene. 20: 4917-25. PMID 11526476 DOI: 10.1038/Sj.Onc.1204529 |
0.07 |
|
| 2008 |
Shen HC, Rosen JE, Yang LM, Savage SA, Burns AL, Mateo CM, Agarwal SK, Chandrasekharappa SC, Spiegel AM, Collins FS, Marx SJ, Libutti SK. Parathyroid tumor development involves deregulation of homeobox genes. Endocrine-Related Cancer. 15: 267-75. PMID 18310293 DOI: 10.1677/Erc-07-0191 |
0.07 |
|
| 1999 |
Zhao XM, Hauache O, Goldsmith PK, Collins R, Spiegel AM. A missense mutation in the seventh transmembrane domain constitutively activates the human Ca2+ receptor. Febs Letters. 448: 180-4. PMID 10217436 DOI: 10.1016/S0014-5793(99)00368-3 |
0.07 |
|
| 2003 |
Sukhodolets KE, Hickman AB, Agarwal SK, Sukhodolets MV, Obungu VH, Novotny EA, Crabtree JS, Chandrasekharappa SC, Collins FS, Spiegel AM, Burns AL, Marx SJ. The 32-kilodalton subunit of replication protein A interacts with menin, the product of the MEN1 tumor suppressor gene. Molecular and Cellular Biology. 23: 493-509. PMID 12509449 DOI: 10.1128/Mcb.23.2.493-509.2003 |
0.069 |
|
| 1996 |
Lubensky IA, Debelenko LV, Zhuang Z, Emmert-Buck MR, Dong Q, Chandrasekharappa S, Guru SC, Manickam P, Olufemi SE, Marx SJ, Spiegel AM, Collins FS, Liotta LA. Allelic deletions on chromosome 11q13 in multiple tumors from individual MEN1 patients. Cancer Research. 56: 5272-8. PMID 8912868 |
0.069 |
|
| 2001 |
Schussheim DH, Skarulis MC, Agarwal SK, Simonds WF, Burns AL, Spiegel AM, Marx SJ. Multiple endocrine neoplasia type 1: new clinical and basic findings. Trends in Endocrinology and Metabolism: Tem. 12: 173-8. PMID 11295574 DOI: 10.1016/S1043-2760(00)00372-6 |
0.069 |
|
| 1993 |
Dohlman HG, Goldsmith P, Spiegel AM, Thorner J. Pheromone action regulates G-protein alpha-subunit myristoylation in the yeast Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 90: 9688-92. PMID 8415763 DOI: 10.1073/Pnas.90.20.9688 |
0.069 |
|
| 1991 |
Fargin A, Yamamoto K, Cotecchia S, Goldsmith PK, Spiegel AM, Lapetina EG, Caron MG, Lefkowitz RJ. Dual coupling of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein. Cellular Signalling. 3: 547-57. PMID 1786205 DOI: 10.1016/0898-6568(91)90031-O |
0.069 |
|
| 1999 |
Berger AC, Libutti SK, Bartlett DL, Skarulis MG, Marx SJ, Spiegel AM, Doppman JL, Alexander HR. Heterogeneous gland size in sporadic multiple gland parathyroid hyperplasia. Journal of the American College of Surgeons. 188: 382-9. PMID 10195722 DOI: 10.1016/S1072-7515(98)00317-2 |
0.069 |
|
| 2002 |
Hu J, Reyes-Cruz G, Chen W, Jacobson KA, Spiegel AM. Identification of acidic residues in the extracellular loops of the seven-transmembrane domain of the human Ca2+ receptor critical for response to Ca2+ and a positive allosteric modulator. The Journal of Biological Chemistry. 277: 46622-31. PMID 12297503 DOI: 10.1074/Jbc.M207100200 |
0.068 |
|
| 1979 |
Spiegel AM, Downs RW, Aurbach GD. Separation of a guanine nucleotide regulatory unit from the adenylate cyclase complex with GTP affinity chromatography. Journal of Cyclic Nucleotide Research. 5: 3-17. PMID 438399 |
0.068 |
|
| 1989 |
Spiegel AM. Receptor-effector coupling by G-proteins implications for endocrinology. Trends in Endocrinology and Metabolism: Tem. 1: 72-6. PMID 18411094 DOI: 10.1016/1043-2760(89)90006-4 |
0.068 |
|
| 1999 |
Guru SC, Crabtree JS, Brown KD, Dunn KJ, Manickam P, Prasad NB, Wangsa D, Burns AL, Spiegel AM, Marx SJ, Pavan WJ, Collins FS, Chandrasekharappa SC. Isolation, genomic organization, and expression analysis of Men1, the murine homolog of the MEN1 gene. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 10: 592-6. PMID 10341092 DOI: 10.1007/S003359901051 |
0.068 |
|
| 1991 |
Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM. Activating mutations of the stimulatory G protein in the McCune-Albright syndrome. The New England Journal of Medicine. 325: 1688-95. PMID 1944469 DOI: 10.1056/Nejm199112123252403 |
0.068 |
|
| 2003 |
Hu J, Spiegel AM. Naturally occurring mutations of the extracellular Ca2+-sensing receptor: implications for its structure and function. Trends in Endocrinology and Metabolism: Tem. 14: 282-8. PMID 12890593 DOI: 10.1016/S1043-2760(03)00104-8 |
0.068 |
|
| 1996 |
Spiegel AM. Mutations in G proteins and G protein-coupled receptors in endocrine disease. The Journal of Clinical Endocrinology and Metabolism. 81: 2434-42. PMID 8675557 DOI: 10.1210/Jcem.81.7.8675557 |
0.068 |
|
| 1985 |
Skibber JM, Reynolds JC, Spiegel AM, Marx SJ, Fitzpatrick LA, Aurbach GD, Wesley RA, Norton JA. Computerized technetium/thallium scans and parathyroid reoperation. Surgery. 98: 1077-82. PMID 3906975 |
0.067 |
|
| 2000 |
Hauache OM, Hu J, Ray K, Xie R, Jacobson KA, Spiegel AM. Effects of a calcimimetic compound and naturally activating mutations on the human Ca2+ receptor and on Ca2+ receptor/metabotropic glutamate chimeric receptors. Endocrinology. 141: 4156-63. PMID 11089548 DOI: 10.1210/Endo.141.11.7753 |
0.067 |
|
| 2007 |
Hu J, Reyes-Cruz G, Goldsmith PK, Gantt NM, Miller JL, Spiegel AM. Functional effects of monoclonal antibodies to the purified amino-terminal extracellular domain of the human Ca(2+) receptor. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 22: 601-8. PMID 17243861 DOI: 10.1359/Jbmr.070111 |
0.067 |
|
| 1983 |
Levine MA, Downs RW, Moses AM, Breslau NA, Marx SJ, Lasker RD, Rizzoli RE, Aurbach GD, Spiegel AM. Resistance to multiple hormones in patients with pseudohypoparathyroidism. Association with deficient activity of guanine nucleotide regulatory protein. The American Journal of Medicine. 74: 545-56. PMID 6301273 DOI: 10.1016/0002-9343(83)91008-2 |
0.067 |
|
| 1980 |
Marx SJ, Spiegel AM, Brown EM, Downs RW, Attie MF, Stock JL, Levine MA, Aurbach GD. Urinary cyclic 3',5'-adenosine monophosphate (cAMP): an index of the action of parathyroid hormone on the kidney. Progress in Biochemical Pharmacology. 17: 182-9. PMID 6259655 |
0.067 |
|
| 1986 |
Levine MA, Jap TS, Mauseth RS, Downs RW, Spiegel AM. Activity of the stimulatory guanine nucleotide-binding protein is reduced in erythrocytes from patients with pseudohypoparathyroidism and pseudopseudohypoparathyroidism: biochemical, endocrine, and genetic analysis of Albright's hereditary osteodystrophy in six kindreds. The Journal of Clinical Endocrinology and Metabolism. 62: 497-502. PMID 3003142 DOI: 10.1210/Jcem-62-3-497 |
0.067 |
|
| 2000 |
Manickam P, Vogel AM, Agarwal SK, Oda T, Spiegel AM, Marx SJ, Collins FS, Weinstein BM, Chandrasekharappa SC. Isolation, characterization, expression and functional analysis of the zebrafish ortholog of MEN1. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 11: 448-54. PMID 10818209 DOI: 10.1007/S003350010085 |
0.067 |
|
| 1997 |
Guru SC, Olufemi SE, Manickam P, Cummings C, Gieser LM, Pike BL, Bittner ML, Jiang Y, Chinault AC, Nowak NJ, Brzozowska A, Crabtree JS, Wang Y, Roe BA, Weisemann JM, ... ... Spiegel AM, et al. A 2.8-Mb clone contig of the multiple endocrine neoplasia type 1 (MEN1) region at 11q13. Genomics. 42: 436-45. PMID 9205115 DOI: 10.1006/Geno.1997.4783 |
0.066 |
|
| 1986 |
Norton JA, Shawker TH, Jones BL, Spiegel AM, Marx SJ, Fitzpatrick L, Aurbach GD, Doppman JL. Intraoperative ultrasound and reoperative parathyroid surgery: an initial evaluation. World Journal of Surgery. 10: 631-9. PMID 3529650 DOI: 10.1007/Bf01655542 |
0.066 |
|
| 1982 |
Stock JL, Weintraub BD, Rosen SW, Aurbach GD, Spiegel AM, Marx SJ. Human chorionic gonadotropin subunit measurement in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 54: 57-63. PMID 6274898 DOI: 10.1210/Jcem-54-1-57 |
0.066 |
|
| 1991 |
Cormont M, Le Marchand-Brustel Y, Van Obberghen E, Spiegel AM, Sharp GW. Identification of G protein alpha-subunits in RINm5F cells and their selective interaction with galanin receptor. Diabetes. 40: 1170-6. PMID 1718802 |
0.066 |
|
| 1988 |
Weinstein LS, Spiegel AM, Carter AD. Cloning and characterization of the human gene for the alpha-subunit of Gi2, a GTP-binding signal transduction protein. Febs Letters. 232: 333-40. PMID 2837412 DOI: 10.1016/0014-5793(88)80764-6 |
0.066 |
|
| 1999 |
Riminucci M, Liu B, Corsi A, Shenker A, Spiegel AM, Robey PG, Bianco P. The histopathology of fibrous dysplasia of bone in patients with activating mutations of the Gs alpha gene: site-specific patterns and recurrent histological hallmarks. The Journal of Pathology. 187: 249-58. PMID 10365102 DOI: 10.1002/(Sici)1096-9896(199901)187:2<249::Aid-Path222>3.0.Co;2-J |
0.065 |
|
| 1993 |
Pamukcu R, Spiegel AM, Chang EB. Biochemical and immunochemical localization of GTP-binding proteins in the rat ileal enterocyte. The Journal of Laboratory and Clinical Medicine. 121: 689-96. PMID 8478596 |
0.065 |
|
| 1993 |
LaMorte VJ, Harootunian AT, Spiegel AM, Tsien RY, Feramisco JR. Mediation of growth factor induced DNA synthesis and calcium mobilization by Gq and Gi2. The Journal of Cell Biology. 121: 91-9. PMID 8458876 DOI: 10.1083/Jcb.121.1.91 |
0.065 |
|
| 1989 |
Lester BR, McCarthy JB, Sun ZQ, Smith RS, Furcht LT, Spiegel AM. G-protein involvement in matrix-mediated motility and invasion of high and low experimental metastatic B16 melanoma clones. Cancer Research. 49: 5940-8. PMID 2477150 |
0.064 |
|
| 1988 |
Spiegel AM. Guanine nucleotide binding proteins and signal transduction. Vitamins and Hormones. 44: 47-101. PMID 2853488 DOI: 10.1016/S0083-6729(08)60693-7 |
0.064 |
|
| 1998 |
Ray K, Clapp P, Goldsmith PK, Spiegel AM. Identification of the sites of N-linked glycosylation on the human calcium receptor and assessment of their role in cell surface expression and signal transduction. The Journal of Biological Chemistry. 273: 34558-67. PMID 9852126 DOI: 10.1074/Jbc.273.51.34558 |
0.064 |
|
| 1999 |
Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Skarulis MC, James LA, Goldsmith PK, Saggar SK, Park SY, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, et al. Multiple endocrine neoplasia type 1: clinical and genetic features of the hereditary endocrine neoplasias. Recent Progress in Hormone Research. 54: 397-438; discussion . PMID 10548885 |
0.064 |
|
| 1990 |
Weinstein LS, Gejman PV, Friedman E, Kadowaki T, Collins RM, Gershon ES, Spiegel AM. Mutations of the Gs alpha-subunit gene in Albright hereditary osteodystrophy detected by denaturing gradient gel electrophoresis. Proceedings of the National Academy of Sciences of the United States of America. 87: 8287-90. PMID 2122458 DOI: 10.1073/Pnas.87.21.8287 |
0.064 |
|
| 1997 |
Guru SC, Agarwal SK, Manickam P, Olufemi SE, Crabtree JS, Weisemann JM, Kester MB, Kim YS, Wang Y, Emmert-Buck MR, Liotta LA, Spiegel AM, Boguski MS, Roe BA, Collins FS, et al. A transcript map for the 2.8-Mb region containing the multiple endocrine neoplasia type 1 locus. Genome Research. 7: 725-35. PMID 9253601 DOI: 10.1101/Gr.7.7.725 |
0.063 |
|
| 1992 |
Friedman E, De Marco L, Gejman PV, Norton JA, Bale AE, Aurbach GD, Spiegel AM, Marx SJ. Allelic loss from chromosome 11 in parathyroid tumors. Cancer Research. 52: 6804-9. PMID 1360870 |
0.063 |
|
| 1991 |
Marx SJ, Menczel J, Campbell G, Aurbach GD, Spiegel AM, Norton JA. Heterogeneous size of the parathyroid glands in familial multiple endocrine neoplasia type 1. Clinical Endocrinology. 35: 521-6. PMID 1685109 DOI: 10.1111/J.1365-2265.1991.Tb00938.X |
0.063 |
|
| 1992 |
Spiegel AM. G proteins in cellular control. Current Opinion in Cell Biology. 4: 203-11. PMID 1318059 DOI: 10.1016/0960-9822(92)90519-G |
0.063 |
|
| 1997 |
Riminucci M, Fisher LW, Shenker A, Spiegel AM, Bianco P, Gehron Robey P. Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation. The American Journal of Pathology. 151: 1587-600. PMID 9403710 |
0.063 |
|
| 2010 |
Spiegel AM. Commentary: new guidelines for NIH peer review: improving the system or undermining it? Academic Medicine : Journal of the Association of American Medical Colleges. 85: 746-8. PMID 20520019 DOI: 10.1097/ACM.0b013e3181d7e130 |
0.062 |
|
| 1979 |
Brown EM, Gardner DG, Brennan MF, Marx SJ, Spiegel AM, Attie MF, Downs RW, Doppman JL, Aurbach CD. Calcium-regulated parathyroid hormone release in primary hyperparathyroidism: studies in vitro with dispersed parathyroid cells. The American Journal of Medicine. 66: 923-31. PMID 453225 DOI: 10.1016/0002-9343(79)90446-7 |
0.062 |
|
| 1984 |
Tam CS, Heersche JN, Santora A, Spiegel AM. Skeletal response in rats following the implantation of hypercalcemia-producing Leydig cell tumors. Metabolism: Clinical and Experimental. 33: 50-3. PMID 6690886 DOI: 10.1016/0026-0495(84)90161-6 |
0.062 |
|
| 1991 |
Bégeot M, Langlois D, Spiegel AM, Saez JM. Regulation of guanine nucleotide binding regulatory proteins in cultured adrenal cells by adrenocorticotropin and angiotensin-II. Endocrinology. 128: 3162-8. PMID 1645263 DOI: 10.1210/Endo-128-6-3162 |
0.062 |
|
| 1996 |
Dong Q, Brucker-Davis F, Weintraub BD, Smallridge RC, Carr FE, Battey J, Spiegel AM, Shenker A. Screening of candidate oncogenes in human thyrotroph tumors: absence of activating mutations of the G alpha q, G alpha 11, G alpha s, or thyrotropin-releasing hormone receptor genes. The Journal of Clinical Endocrinology and Metabolism. 81: 1134-40. PMID 8772588 DOI: 10.1210/Jcem.81.3.8772588 |
0.062 |
|
| 1990 |
Senogles SE, Spiegel AM, Padrell E, Iyengar R, Caron MG. Specificity of receptor-G protein interactions. Discrimination of Gi subtypes by the D2 dopamine receptor in a reconstituted system. The Journal of Biological Chemistry. 265: 4507-14. PMID 2137824 |
0.062 |
|
| 1977 |
Spiegel AM, Downs RW, Aurbach GD. Guanosine 5', alpha-beta-methylene, triphosphate, a novel GTP analog, causes persistent activation of adenylate cyclase: evidence against pyrophosphorylation mechanism. Biochemical and Biophysical Research Communications. 76: 758-64. PMID 197925 DOI: 10.1016/0006-291X(77)91565-0 |
0.062 |
|
| 1999 |
Vortmeyer AO, Lubensky IA, Skarulis M, Li G, Moon YW, Park WS, Weil R, Barlow C, Spiegel AM, Marx SJ, Zhuang Z. Multiple endocrine neoplasia type 1: atypical presentation, clinical course, and genetic analysis of multiple tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 12: 919-24. PMID 10496602 |
0.061 |
|
| 1999 |
Heppner C, Reincke M, Agarwal SK, Mora P, Allolio B, Burns AL, Spiegel AM, Marx SJ. MEN1 gene analysis in sporadic adrenocortical neoplasms. The Journal of Clinical Endocrinology and Metabolism. 84: 216-9. PMID 9920087 DOI: 10.1210/Jcem.84.1.5388 |
0.061 |
|
| 1991 |
Spiegel AM. Pathophysiology of primary hyperparathyroidism. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 6: S15-7; discussion S3. PMID 1763667 DOI: 10.1002/jbmr.5650061407 |
0.061 |
|
| 1993 |
Shenker A, Weinstein LS, Moran A, Pescovitz OH, Charest NJ, Boney CM, Van Wyk JJ, Merino MJ, Feuillan PP, Spiegel AM. Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein GS. The Journal of Pediatrics. 123: 509-18. PMID 8410501 DOI: 10.1016/S0022-3476(05)80943-6 |
0.061 |
|
| 1999 |
Marx SJ, Agarwal SK, Heppner C, Kim YS, Kester MB, Goldsmith PK, Skarulis MC, Spiegel AM, Burns AL, Debelenko LV, Zhuang Z, Lubensky IA, Liotta LA, Emmert-Buck MR, Guru SC, et al. The gene for multiple endocrine neoplasia type 1: recent findings. Bone. 25: 119-22. PMID 10423035 DOI: 10.1016/S8756-3282(99)00112-X |
0.061 |
|
| 1988 |
Backlund PS, Aksamit RR, Unson CG, Goldsmith P, Spiegel AM, Milligan G. Immunochemical and electrophoretic characterization of the major pertussis toxin substrate of the RAW264 macrophage cell line. Biochemistry. 27: 2040-6. PMID 3132205 DOI: 10.1021/Bi00406A034 |
0.061 |
|
| 1994 |
Shenker A, Weinstein LS, Sweet DE, Spiegel AM. An activating Gs alpha mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. The Journal of Clinical Endocrinology and Metabolism. 79: 750-5. PMID 8077356 DOI: 10.1210/Jcem.79.3.8077356 |
0.061 |
|
| 1999 |
Ray K, Hauschild BC, Steinbach PJ, Goldsmith PK, Hauache O, Spiegel AM. Identification of the cysteine residues in the amino-terminal extracellular domain of the human Ca(2+) receptor critical for dimerization. Implications for function of monomeric Ca(2+) receptor. The Journal of Biological Chemistry. 274: 27642-50. PMID 10488104 DOI: 10.1074/jbc.274.39.27642 |
0.061 |
|
| 1997 |
Ray K, Fan GF, Goldsmith PK, Spiegel AM. The carboxyl terminus of the human calcium receptor. Requirements for cell-surface expression and signal transduction. The Journal of Biological Chemistry. 272: 31355-61. PMID 9395465 DOI: 10.1074/Jbc.272.50.31355 |
0.06 |
|
| 1988 |
Collu R, Bouvier C, Lagacé G, Unson CG, Milligan G, Goldsmith P, Spiegel AM. Selective deficiency of guanine nucleotide-binding protein Go in two dopamine-resistant pituitary tumors. Endocrinology. 122: 1176-8. PMID 3125040 DOI: 10.1210/Endo-122-3-1176 |
0.06 |
|
| 1982 |
Brennan MF, Doppman JL, Kurdy AG, Marx SJ, Spiegel AM, Aurbach GD. Assessment of techniques for preoperative parathyroid gland localization in patients undergoing reoperation for hyperparathyroidism. Surgery. 91: 6-11. PMID 7054909 |
0.06 |
|
| 1982 |
Spiegel AM, Levine MA, Aurbach GD, Downs RW, Marx SJ, Lasker RD, Moses AM, Breslau NA. Deficiency of hormone receptor-adenylate cyclase coupling protein: basis for hormone resistance in pseudohypoparathyroidism. The American Journal of Physiology. 243: E37-42. PMID 6283911 DOI: 10.1152/Ajpendo.1982.243.1.E37 |
0.06 |
|
| 1982 |
Marx SJ, Spiegel AM, Levine MA, Rizzoli RE, Lasker RD, Santora AC, Downs RW, Aurbach GD. Familial hypocalciuric hypercalcemia: the relation to primary parathyroid hyperplasia. The New England Journal of Medicine. 307: 416-26. PMID 7045673 DOI: 10.1056/Nejm198208123070707 |
0.06 |
|
| 1997 |
Goldsmith PK, Fan G, Miller JL, Rogers KV, Spiegel AM. Monoclonal antibodies against synthetic peptides corresponding to the extracellular domain of the human Ca2+ receptor: characterization and use in studying concanavalin A inhibition. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 12: 1780-8. PMID 9383682 DOI: 10.1359/Jbmr.1997.12.11.1780 |
0.06 |
|
| 1992 |
Weinstein LS, Gejman PV, de Mazancourt P, American N, Spiegel AM. A heterozygous 4-bp deletion mutation in the Gs alpha gene (GNAS1) in a patient with Albright hereditary osteodystrophy. Genomics. 13: 1319-21. PMID 1505964 DOI: 10.1016/0888-7543(92)90056-X |
0.06 |
|
| 1983 |
Levine MA, Eil C, Downs RW, Spiegel AM. Deficient guanine nucleotide regulatory unit activity in cultured fibroblast membranes from patients with pseudohypoparathyroidism type I. a cause of impaired synthesis of 3',5'-cyclic AMP by intact and broken cells. The Journal of Clinical Investigation. 72: 316-24. PMID 6308048 DOI: 10.1172/Jci110971 |
0.059 |
|
| 1988 |
Milligan G, Mullaney I, Unson CG, Marshall L, Spiegel AM, McArdle H. GTP analogues promote release of the alpha subunit of the guanine nucleotide binding protein, Gi2, from membranes of rat glioma C6 BU1 cells. The Biochemical Journal. 254: 391-6. PMID 3140801 DOI: 10.1042/Bj2540391 |
0.059 |
|
| 1977 |
Marx SJ, Spiegel AM, Brown EM, Aurbach GD. Family studies in patients with primary parathyroid hyperplasia. The American Journal of Medicine. 62: 698-706. PMID 871127 DOI: 10.1016/0002-9343(77)90873-7 |
0.059 |
|
| 1996 |
Wenkert D, Schoneberg T, Merendino JJ, Rodriguez Pena MS, Vinitsky R, Goldsmith PK, Wess J, Spiegel AM. Functional characterization of five V2 vasopressin receptor gene mutations. Molecular and Cellular Endocrinology. 124: 43-50. PMID 9027323 DOI: 10.1016/S0303-7207(96)03926-3 |
0.059 |
|
| 1998 |
Guru SC, Manickam P, Crabtree JS, Olufemi SE, Agarwal SK, Debelenko LV, Zhuang Z, Lubensky IA, Kester MB, Kim YS, Heppner C, Weisemann JM, Boguski MS, Wang Y, Roe BA, ... ... Spiegel AM, et al. Identification and characterization of the multiple endocrine neoplasia type 1 (MEN1) gene Journal of Internal Medicine. 243: 433-439. PMID 9681840 DOI: 10.1046/j.1365-2796.1998.00346.x |
0.059 |
|
| 1979 |
Brennan MF, Brown EM, Spiegel AM, Marx SJ, Doppman JL, Jones DC, Aurbach GD. Autotransplantation of cryopreserved parathyroid tissue in man. Annals of Surgery. 189: 139-42. PMID 426546 DOI: 10.1097/00000658-197902000-00002 |
0.059 |
|
| 1993 |
Sugg SL, Fraker DL, Alexander R, Doppman JL, Miller DL, Chang R, Skarulis MC, Marx SJ, Spiegel AM, Norton JA. Prospective evaluation of selective venous sampling for parathyroid hormone concentration in patients undergoing reoperations for primary hyperparathyroidism. Surgery. 114: 1004-9; discussion 1. PMID 8256203 DOI: 10.5555/Uri:Pii:0039606093903155 |
0.059 |
|
| 1978 |
Brennan MF, Brown EM, Marx SJ, Spiegel AM, Broadus AE, Doppman JL, Webber B, Aurbach GD. Recurrent hyperparathyroidism from an autotransplanted parathyroid adenoma. The New England Journal of Medicine. 299: 1057-9. PMID 703772 DOI: 10.1056/Nejm197811092991909 |
0.059 |
|
| 1998 |
Collins MT, Skarulis MC, Bilezikian JP, Silverberg SJ, Spiegel AM, Marx SJ. Treatment of hypercalcemia secondary to parathyroid carcinoma with a novel calcimimetic agent. The Journal of Clinical Endocrinology and Metabolism. 83: 1083-8. PMID 9543122 DOI: 10.1210/Jcem.83.4.4726 |
0.058 |
|
| 1987 |
Spiegel AM. Signal transduction by guanine nucleotide binding proteins. Molecular and Cellular Endocrinology. 49: 1-16. PMID 2435586 DOI: 10.1016/0303-7207(87)90058-X |
0.058 |
|
| 1997 |
Dong Q, Debelenko LV, Chandrasekharappa SC, Emmert-Buck MR, Zhuang Z, Guru SC, Manickam P, Skarulis M, Lubensky IA, Liotta LA, Collins FS, Marx SJ, Spiegel AM. Loss of heterozygosity at 11q13: analysis of pituitary tumors, lung carcinoids, lipomas, and other uncommon tumors in subjects with familial multiple endocrine neoplasia type 1. The Journal of Clinical Endocrinology and Metabolism. 82: 1416-20. PMID 9141526 DOI: 10.1210/Jcem.82.5.3944 |
0.058 |
|
| 1988 |
Spiegel AM. G proteins in clinical medicine. Hospital Practice (Office Ed.). 23: 93-100, 105-6, 111-2. PMID 2454242 DOI: 10.1080/21548331.1988.11703488 |
0.058 |
|
| 2000 |
Goebel SU, Heppner C, Burns AL, Marx SJ, Spiegel AM, Zhuang Z, Lubensky IA, Gibril F, Jensen RT, Serrano J. Genotype/phenotype correlation of multiple endocrine neoplasia type 1 gene mutations in sporadic gastrinomas. The Journal of Clinical Endocrinology and Metabolism. 85: 116-23. PMID 10634374 DOI: 10.1210/Jcem.85.1.6260 |
0.058 |
|
| 1997 |
Zhuang Z, Ezzat SZ, Vortmeyer AO, Weil R, Oldfield EH, Park WS, Pack S, Huang S, Agarwal SK, Guru SC, Manickam P, Debelenko LV, Kester MB, Olufemi SE, Heppner C, ... ... Spiegel AM, et al. Mutations of the MEN1 tumor suppressor gene in pituitary tumors. Cancer Research. 57: 5446-51. PMID 9407947 |
0.058 |
|
| 1997 |
Spiegel AM. Inborn errors of signal transduction: mutations in G proteins and G protein-coupled receptors as a cause of disease. Journal of Inherited Metabolic Disease. 20: 113-21. PMID 9211183 DOI: 10.1023/A:1005393501786 |
0.058 |
|
| 1992 |
Juhnn YS, Jones TL, Spiegel AM. Amino- and carboxy-terminal deletion mutants of Gs alpha are localized to the particulate fraction of transfected COS cells. The Journal of Cell Biology. 119: 523-30. PMID 1400589 DOI: 10.1083/Jcb.119.3.523 |
0.058 |
|
| 2000 |
Hu J, Hauache O, Spiegel AM. Human Ca2+ receptor cysteine-rich domain. Analysis of function of mutant and chimeric receptors. The Journal of Biological Chemistry. 275: 16382-9. PMID 10747888 DOI: 10.1074/Jbc.M000277200 |
0.058 |
|
| 1981 |
Marx SJ, Attie MF, Stock JL, Spiegel AM, Levine MA. Maximal urine-concentrating ability: familial hypocalciuric hypercalcemia versus typical primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 52: 736-40. PMID 6259192 DOI: 10.1210/Jcem-52-4-736 |
0.058 |
|
| 1997 |
Darling TN, Skarulis MC, Steinberg SM, Marx SJ, Spiegel AM, Turner M. Multiple facial angiofibromas and collagenomas in patients with multiple endocrine neoplasia type 1. Archives of Dermatology. 133: 853-7. PMID 9236523 DOI: 10.1001/Archderm.1997.03890430067009 |
0.057 |
|
| 1983 |
Spiegel AM, Marx SJ. Parathyroid hormone and vitamin D receptors. Clinics in Endocrinology and Metabolism. 12: 221-41. PMID 6303646 DOI: 10.1016/S0300-595X(83)80037-1 |
0.057 |
|
| 1997 |
Debelenko LV, Emmert-Buck MR, Manickam P, Kester M, Guru SC, DiFranco EM, Olufemi SE, Agarwal S, Lubensky IA, Zhuang Z, Burns AL, Spiegel AM, Liotta LA, Collins FS, Marx SJ, et al. Haplotype analysis defines a minimal interval for the multiple endocrine neoplasia type 1 (MEN1) gene. Cancer Research. 57: 1039-42. PMID 9067266 |
0.057 |
|
| 1984 |
Krudy AG, Shawker TH, Doppman JL, Horvath K, Schneider PD, Norton JA, Marx SJ, Spiegel AM. Ultrasonic parathyroid localisation in previously operated patients. Clinical Radiology. 35: 113-8. PMID 6697653 DOI: 10.1016/S0009-9260(84)80007-0 |
0.057 |
|
| 1995 |
Chen CC, Skarulis MC, Fraker DL, Alexander R, Marx SJ, Spiegel AM. Technetium-99m-sestamibi imaging before reoperation for primary hyperparathyroidism. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 36: 2186-91. PMID 8523102 |
0.057 |
|
| 1997 |
Manickam P, Guru SC, Debelenko LV, Agarwal SK, Olufemi SE, Weisemann JM, Boguski MS, Crabtree JS, Wang Y, Roe BA, Lubensky IA, Zhuang Z, Kester MB, Burns AL, Spiegel AM, et al. Eighteen new polymorphic markers in the multiple endocrine neoplasia type 1 (MEN1) region. Human Genetics. 101: 102-8. PMID 9385379 DOI: 10.1007/s004390050595 |
0.056 |
|
| 1997 |
Debelenko LV, Zhuang Z, Emmert-Buck MR, Chandrasekharappa SC, Manickam P, Guru SC, Marx SJ, Skarulis MC, Spiegel AM, Collins FS, Jensen RT, Liotta LA, Lubensky IA. Allelic deletions on chromosome 11q13 in multiple endocrine neoplasia type 1-associated and sporadic gastrinomas and pancreatic endocrine tumors. Cancer Research. 57: 2238-43. PMID 9187127 |
0.056 |
|
| 1997 |
Rodriguez-Pena MS, Collins R, Woodard C, Spiegel AM. Decreased insulin content and secretion in RIN 1046-38 cells overexpressing alpha 2-adrenergic receptors. Endocrine. 7: 255-60. PMID 9549052 DOI: 10.1007/Bf02778148 |
0.056 |
|
| 1990 |
Spiegel AM. Albright's hereditary osteodystrophy and defective G proteins. The New England Journal of Medicine. 322: 1461-2. PMID 2109829 DOI: 10.1056/Nejm199005173222010 |
0.056 |
|
| 1989 |
Simonds WF, Goldsmith PK, Codina J, Unson CG, Spiegel AM. Gi2 mediates alpha 2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with G alpha C-terminal antibodies. Proceedings of the National Academy of Sciences of the United States of America. 86: 7809-13. PMID 2510151 DOI: 10.1073/Pnas.86.20.7809 |
0.056 |
|
| 1984 |
Krudy AG, Doppman JL, Shawker TH, Spiegel AM, Marx SJ, Norton J, Schaaf M, Moss ML, Weiss MA, Schachner SH. Hyperfunctioning cystic parathyroid glands: CT and sonographic findings. Ajr. American Journal of Roentgenology. 142: 175-8. PMID 6606954 DOI: 10.2214/Ajr.142.1.175 |
0.056 |
|
| 1993 |
Jones TL, Woodard C, Spiegel AM. Baculovirus expression and purification of a soluble, mutant G-protein alpha subunit. Protein Expression and Purification. 4: 64-71. PMID 8425110 DOI: 10.1006/Prep.1993.1010 |
0.056 |
|
| 1991 |
Shenker A, Goldsmith P, Unson CG, Spiegel AM. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. The Journal of Biological Chemistry. 266: 9309-13. PMID 1851174 |
0.056 |
|
| 1985 |
Cerione RA, Staniszewski C, Benovic JL, Lefkowitz RJ, Caron MG, Gierschik P, Somers R, Spiegel AM, Codina J, Birnbaumer L. Specificity of the functional interactions of the beta-adrenergic receptor and rhodopsin with guanine nucleotide regulatory proteins reconstituted in phospholipid vesicles. The Journal of Biological Chemistry. 260: 1493-500. PMID 2981858 |
0.055 |
|
| 1980 |
Levine MA, Downs RW, Singer M, Marx SJ, Aurbach GD, Spiegel AM. Deficient activity of guanine nucleotide regulatory protein in erythrocytes from patients with pseudohypoparathyroidism. Biochemical and Biophysical Research Communications. 94: 1319-24. PMID 6249307 DOI: 10.1016/0006-291X(80)90563-X |
0.055 |
|
| 1982 |
Spiegel AM, Levine MA. Pseudohypoparathyroidism: deficiency of hormone receptor-adenylate cyclase coupling protein as a cause of hereditary hormone resistance. Progress in Clinical and Biological Research. 97: 327-40. PMID 6296880 |
0.055 |
|
| 1990 |
Backlund PS, Simonds WF, Spiegel AM. Carboxyl methylation and COOH-terminal processing of the brain G-protein gamma-subunit. The Journal of Biological Chemistry. 265: 15572-6. PMID 2118528 |
0.055 |
|
| 1991 |
Holter W, Spiegel AM, Howard BH, Weber S, Brann MR. Expression of GTP-binding proteins and prostaglandin E2 receptors during human T cell activation. Cellular Immunology. 134: 287-95. PMID 1850662 DOI: 10.1016/0008-8749(91)90303-S |
0.055 |
|
| 1992 |
Chiavaroli C, Cooper DM, Boyajian CL, Murray-Whelan R, Demaurex N, Spiegel AM, Schlegel W. Spontaneous Intracellular Calcium Oscillations and G(s) α Subunit Expression are Inversely Correlated with Secretory Granule Content in Pituitary Cells. Journal of Neuroendocrinology. 4: 473-81. PMID 21554632 DOI: 10.1111/j.1365-2826.1992.tb00195.x |
0.055 |
|
| 1992 |
Chiavaroli C, Cooper DMF, Boyajian CL, Murray-Whelan R, Demaurex N, Spiegel AM, Schlegel W. Spontaneous intracellular calcium oscillations and G(s)α subunit expression are inversely correlated with secretory granule content in pituitary cells Journal of Neuroendocrinology. 4: 473-481. |
0.055 |
|
| 1978 |
Marx SJ, Spiegel AM, Brown EM, Gardner DG, Downs RW, Attie M, Hamstra AJ, DeLuca HF. A familial syndrome of decrease in sensitivity to 1,25-dihydroxyvitamin D. The Journal of Clinical Endocrinology and Metabolism. 47: 1303-10. PMID 233695 DOI: 10.1210/Jcem-47-6-1303 |
0.055 |
|
| 1997 |
Emmert-Buck MR, Lubensky IA, Dong Q, Manickam P, Guru SC, Kester MB, Olufemi SE, Agarwal S, Burns AL, Spiegel AM, Collins FS, Marx SJ, Zhuang Z, Liotta LA, Chandrasekharappa SC, et al. Localization of the multiple endocrine neoplasia type I (MEN1) gene based on tumor loss of heterozygosity analysis. Cancer Research. 57: 1855-8. PMID 9157974 |
0.055 |
|
| 1993 |
Degtyarev MY, Spiegel AM, Jones TL. Increased palmitoylation of the Gs protein alpha subunit after activation by the beta-adrenergic receptor or cholera toxin. The Journal of Biological Chemistry. 268: 23769-72. PMID 8226908 |
0.055 |
|
| 2003 |
Agarwal SK, Novotny EA, Crabtree JS, Weitzman JB, Yaniv M, Burns AL, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. Transcription factor JunD, deprived of menin, switches from growth suppressor to growth promoter. Proceedings of the National Academy of Sciences of the United States of America. 100: 10770-5. PMID 12960363 DOI: 10.1073/Pnas.1834524100 |
0.054 |
|
| 1987 |
Milligan G, Spiegel AM, Unson CG, Saggerson ED. Chemically induced hypothyroidism produces elevated amounts of the alpha subunit of the inhibitory guanine nucleotide binding protein (Gi) and the beta subunit common to all G-proteins. The Biochemical Journal. 247: 223-7. PMID 3120702 |
0.054 |
|
| 1998 |
Olufemi SE, Green JS, Manickam P, Guru SC, Agarwal SK, Kester MB, Dong Q, Burns AL, Spiegel AM, Marx SJ, Collins FS, Chandrasekharappa SC. Common ancestral mutation in the MEN1 gene is likely responsible for the prolactinoma variant of MEN1 (MEN1Burin) in four kindreds from Newfoundland. Human Mutation. 11: 264-9. PMID 9554741 DOI: 10.1002/(Sici)1098-1004(1998)11:4<264::Aid-Humu2>3.0.Co;2-V |
0.054 |
|
| 1999 |
Agarwal SK, Guru SC, Heppner C, Erdos MR, Collins RM, Park SY, Saggar S, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ, Burns AL. Menin interacts with the AP1 transcription factor JunD and represses JunD-activated transcription. Cell. 96: 143-52. PMID 9989505 DOI: 10.1016/S0092-8674(00)80967-8 |
0.054 |
|
| 1997 |
Debelenko LV, Brambilla E, Agarwal SK, Swalwell JI, Kester MB, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Chandrasekharappa SC, Crabtree JS, Kim YS, Heppner C, Burns AL, ... Spiegel AM, et al. Identification of MEN1 gene mutations in sporadic carcinoid tumors of the lung. Human Molecular Genetics. 6: 2285-90. PMID 9361035 DOI: 10.1093/Hmg/6.13.2285 |
0.053 |
|
| 1978 |
Brennan MF, Doppman JL, Marx SJ, Spiegel AM, Brown EM, Aurbach GD. Reoperative parathyroid surgery for persistent hyperparathyroidism. Surgery. 83: 669-76. PMID 644460 |
0.053 |
|
| 1985 |
Dufour DR, Marx SJ, Spiegel AM. Parathyroid gland morphology in nonparathyroid hormone-mediated hypercalcemia. The American Journal of Surgical Pathology. 9: 43-51. PMID 3970297 |
0.053 |
|
| 1987 |
Kern KA, Shawker TH, Doppman JL, Miller DL, Marx SJ, Spiegel AM, Aurbach GD, Norton JA. The use of high-resolution ultrasound to locate parathyroid tumors during reoperations for primary hyperparathyroidism. World Journal of Surgery. 11: 579-85. PMID 3314177 DOI: 10.1007/Bf01655831 |
0.053 |
|
| 1991 |
Hamilton SL, Codina J, Hawkes MJ, Yatani A, Sawada T, Strickland FM, Froehner SC, Spiegel AM, Toro L, Stefani E. Evidence for direct interaction of Gs alpha with the Ca2+ channel of skeletal muscle. The Journal of Biological Chemistry. 266: 19528-35. PMID 1655789 |
0.053 |
|
| 1996 |
Doppman JL, Skarulis MC, Chen CC, Chang R, Pass HI, Fraker DL, Alexander HR, Niederle B, Marx SJ, Norton JA, Wells SA, Spiegel AM. Parathyroid adenomas in the aortopulmonary window. Radiology. 201: 456-62. PMID 8888240 DOI: 10.1148/Radiology.201.2.8888240 |
0.052 |
|
| 1989 |
Simonds WF, Goldsmith PK, Woodard CJ, Unson CG, Spiegel AM. Receptor and effector interactions of Gs. Functional studies with antibodies to the alpha s carboxyl-terminal decapeptide. Febs Letters. 249: 189-94. PMID 2500363 DOI: 10.1016/0014-5793(89)80622-2 |
0.052 |
|
| 1991 |
Gejman PV, Weinstein LS, Martinez M, Spiegel AM, Cao Q, Hsieh WT, Hoehe MR, Gershon ES. Genetic mapping of the Gs-alpha subunit gene (GNAS1) to the distal long arm of chromosome 20 using a polymorphism detected by denaturing gradient gel electrophoresis. Genomics. 9: 782-3. PMID 1674732 DOI: 10.1016/0888-7543(91)90377-Q |
0.052 |
|
| 1994 |
MacFarlane MP, Fraker DL, Shawker TH, Norton JA, Doppman JL, Chang RA, Skarulis MC, Marx SJ, Spiegel AM, Alexander HR. Use of preoperative fine-needle aspiration in patients undergoing reoperation for primary hyperparathyroidism. Surgery. 116: 959-64; discussion 9. PMID 7985103 |
0.052 |
|
| 1981 |
Stock JL, Krudy AG, Doppman JL, Jones AE, Brennan MF, Attie MF, Downs RW, Levine MA, Marx SJ, Spiegel AM, Aurbach GD. Parathyroid imaging after intraarterial injections of [75Se]selenomethionine. The Journal of Clinical Endocrinology and Metabolism. 52: 835-9. PMID 7228990 DOI: 10.1210/Jcem-52-5-835 |
0.051 |
|
| 1986 |
Cerione RA, Regan JW, Nakata H, Codina J, Benovic JL, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Lefkowitz RJ. Functional reconstitution of the alpha 2-adrenergic receptor with guanine nucleotide regulatory proteins in phospholipid vesicles. The Journal of Biological Chemistry. 261: 3901-9. PMID 3005307 |
0.051 |
|
| 1995 |
Dong Q, Shenker A, Way J, Haddad BR, Lin K, Hughes MR, McBride OW, Spiegel AM, Battey J. Molecular cloning of human G alpha q cDNA and chromosomal localization of the G alpha q gene (GNAQ) and a processed pseudogene. Genomics. 30: 470-75. PMID 8825633 DOI: 10.1006/Geno.1995.1267 |
0.051 |
|
| 1987 |
Miller DL, Doppman JL, Krudy AG, Shawker TH, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part II. Invasive procedures. Radiology. 162: 138-41. PMID 3538146 DOI: 10.1148/Radiology.162.1.3538146 |
0.051 |
|
| 1999 |
Kim YS, Burns AL, Goldsmith PK, Heppner C, Park SY, Chandrasekharappa SC, Collins FS, Spiegel AM, Marx SJ. Stable overexpression of MEN1 suppresses tumorigenicity of RAS. Oncogene. 18: 5936-42. PMID 10557080 DOI: 10.1038/Sj.Onc.1203005 |
0.051 |
|
| 1989 |
Sagi-Eisenberg R, Traub LM, Spiegel AM, Zick Y. Protein kinase C-mediated phosphorylation of retinal rod outer segment membrane proteins. Cellular Signalling. 1: 519-31. PMID 2641684 DOI: 10.1016/0898-6568(89)90036-3 |
0.051 |
|
| 1979 |
Brown EM, Broadus AE, Brennan MF, Gardner DG, Marx SJ, Spiegel AM, Downs RW, Attie M, Aurbach GD. Direct comparison in vivo and in vitro of suppressibility of parathyroid function by calcium in primary hyperparathyroidism. The Journal of Clinical Endocrinology and Metabolism. 48: 604-10. PMID 429506 DOI: 10.1210/Jcem-48-4-604 |
0.05 |
|
| 1987 |
Milligan G, Gierschik P, Spiegel AM. The use of specific antibodies to identify and quantify guanine nucleotide-binding proteins. Biochemical Society Transactions. 15: 42-5. PMID 3104112 DOI: 10.1042/Bst0150042 |
0.05 |
|
| 2000 |
Debelenko LV, Swalwell JI, Kelley MJ, Brambilla E, Manickam P, Baibakov G, Agarwal SK, Spiegel AM, Marx SJ, Chandrasekharappa SC, Collins FS, Travis WD, Emmert-Buck MR. MEN1 gene mutation analysis of high-grade neuroendocrine lung carcinoma. Genes, Chromosomes & Cancer. 28: 58-65. PMID 10738303 DOI: 10.1002/(Sici)1098-2264(200005)28:1<58::Aid-Gcc7>3.0.Co;2-2 |
0.05 |
|
| 1982 |
Lasker RD, Spiegel AM. Endogenous substrates for cAMP-dependent phosphorylation in dispersed bovine parathyroid cells. Endocrinology. 111: 1412-4. PMID 6288362 DOI: 10.1210/Endo-111-4-1412 |
0.05 |
|
| 1987 |
Miller DL, Doppman JL, Chang R, Simmons JT, O'Leary TJ, Norton JA, Spiegel AM, Marx SJ, Aurbach GD. Angiographic ablation of parathyroid adenomas: lessons from a 10-year experience. Radiology. 165: 601-7. PMID 3685340 DOI: 10.1148/Radiology.165.3.3685340 |
0.05 |
|
| 1991 |
Spiegel AM, Backlund PS, Butrynski JE, Jones TL, Simonds WF. The G protein connection: molecular basis of membrane association. Trends in Biochemical Sciences. 16: 338-41. PMID 1949155 DOI: 10.1016/0968-0004(91)90139-M |
0.05 |
|
| 1998 |
Marx S, Spiegel AM, Skarulis MC, Doppman JL, Collins FS, Liotta LA. Multiple endocrine neoplasia type 1: clinical and genetic topics. Annals of Internal Medicine. 129: 484-94. PMID 9735087 DOI: 10.7326/0003-4819-129-6-199809150-00011 |
0.049 |
|
| 1981 |
Downs RW, Reen SA, Levine MA, Aurbach GD, Spiegel AM. Cholera-toxin-dependent ADP-ribosylation of the adenylate cyclase regulatory protein in turkey erythrocyte membranes. Archives of Biochemistry and Biophysics. 209: 284-90. PMID 6269497 DOI: 10.1016/0003-9861(81)90282-4 |
0.049 |
|
| 1986 |
Brandi ML, Aurbach GD, Fitzpatrick LA, Quarto R, Spiegel AM, Bliziotes MM, Norton JA, Doppman JL, Marx SJ. Parathyroid mitogenic activity in plasma from patients with familial multiple endocrine neoplasia type 1. The New England Journal of Medicine. 314: 1287-93. PMID 2871488 DOI: 10.1056/Nejm198605153142004 |
0.049 |
|
| 1983 |
Downs RW, Levine MA, Drezner MK, Burch WM, Spiegel AM. Deficient adenylate cyclase regulatory protein in renal membranes from a patient with pseudohypoparathyroidism. The Journal of Clinical Investigation. 71: 231-5. PMID 6822662 DOI: 10.1172/Jci110763 |
0.049 |
|
| 1988 |
Cerione RA, Kroll S, Rajaram R, Unson C, Goldsmith P, Spiegel AM. An antibody directed against the carboxyl-terminal decapeptide of the alpha subunit of the retinal GTP-binding protein, transducin. Effects on transducin function. The Journal of Biological Chemistry. 263: 9345-52. PMID 2837485 |
0.049 |
|
| 1997 |
Agarwal SK, Kester MB, Debelenko LV, Heppner C, Emmert-Buck MR, Skarulis MC, Doppman JL, Kim YS, Lubensky IA, Zhuang Z, Green JS, Guru SC, Manickam P, Olufemi SE, Liotta LA, ... ... Spiegel AM, et al. Germline mutations of the MEN1 gene in familial multiple endocrine neoplasia type 1 and related states. Human Molecular Genetics. 6: 1169-75. PMID 9215689 DOI: 10.1093/Hmg/6.7.1169 |
0.048 |
|
| 1983 |
Krudy AG, Doppman JL, Miller DL, Marx SJ, Norton JA, Santora AC, Lasker RD, Downs RW, Spiegel AM, Aurbach GD. Work in progress: abnormal parathyroid glands. Comparison of nonselective arterial digital arteriography, selective parathyroid arteriography, and venous digital arteriography as methods of detection. Radiology. 148: 23-9. PMID 6134300 DOI: 10.1148/Radiology.148.1.6134300 |
0.048 |
|
| 1990 |
Fraker DL, Doppman JL, Shawker TH, Marx SJ, Spiegel AM, Norton JA. Undescended parathyroid adenoma: an important etiology for failed operations for primary hyperparathyroidism. World Journal of Surgery. 14: 342-8. PMID 2368436 DOI: 10.1007/Bf01658522 |
0.048 |
|
| 1988 |
McKenzie FR, Kelly EC, Unson CG, Spiegel AM, Milligan G. Antibodies which recognize the C-terminus of the inhibitory guanine-nucleotide-binding protein (Gi) demonstrate that opioid peptides and foetal-calf serum stimulate the high-affinity GTPase activity of two separate pertussis-toxin substrates. The Biochemical Journal. 249: 653-9. PMID 2833223 DOI: 10.1042/Bj2490653 |
0.047 |
|
| 1997 |
Ray K, Fan GF, Goldsmith PK, Spiegel AM. Mutational analysis of the carboxyl-terminal region of the human calcium-sensing receptor Faseb Journal. 11: A1168. |
0.047 |
|
| 1991 |
Hermouet S, Merendino JJ, Gutkind JS, Spiegel AM. Activating and inactivating mutations of the alpha subunit of Gi2 protein have opposite effects on proliferation of NIH 3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 88: 10455-9. PMID 1660138 DOI: 10.1073/Pnas.88.23.10455 |
0.047 |
|
| 1979 |
Brown EM, Brennan MF, Broadus AE, Marx SJ, Gardner DG, Spiegel AM, Downs RW, Attie MF, Aurbach GD. Human parathyroid autografts: comparison of function in vivo and in vitro. The Journal of Clinical Endocrinology and Metabolism. 48: 648-54. PMID 219003 DOI: 10.1210/Jcem-48-4-648 |
0.047 |
|
| 1994 |
Degtyarev MY, Spiegel AM, Jones TL. Palmitoylation of a G protein alpha i subunit requires membrane localization not myristoylation. The Journal of Biological Chemistry. 269: 30898-903. PMID 7983022 |
0.046 |
|
| 1986 |
Zick Y, Sagi-Eisenberg R, Pines M, Gierschik P, Spiegel AM. Multisite phosphorylation of the alpha subunit of transducin by the insulin receptor kinase and protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 83: 9294-7. PMID 3099281 DOI: 10.1073/Pnas.83.24.9294 |
0.046 |
|
| 1991 |
Simonds WF, Butrynski JE, Gautam N, Unson CG, Spiegel AM. G-protein beta gamma dimers. Membrane targeting requires subunit coexpression and intact gamma C-A-A-X domain. The Journal of Biological Chemistry. 266: 5363-6. PMID 1706334 |
0.046 |
|
| 1991 |
Fraker DL, Travis WD, Merendino JJ, Zimering MB, Streeten EA, Weinstein LS, Marx SJ, Spiegel AM, Aurbach GD, Doppman JL. Locally recurrent parathyroid neoplasms as a cause for recurrent and persistent primary hyperparathyroidism. Annals of Surgery. 213: 58-65. PMID 1985539 DOI: 10.1097/00000658-199101000-00010 |
0.046 |
|
| 1997 |
Zhuang Z, Vortmeyer AO, Pack S, Huang S, Pham TA, Wang C, Park WS, Agarwal SK, Debelenko LV, Kester M, Guru SC, Manickam P, Olufemi SE, Yu F, Heppner C, ... ... Spiegel AM, et al. Somatic mutations of the MEN1 tumor suppressor gene in sporadic gastrinomas and insulinomas. Cancer Research. 57: 4682-6. PMID 9354421 |
0.046 |
|
| 1986 |
Cerione RA, Staniszewski C, Gierschik P, Codina J, Somers RL, Birnbaumer L, Spiegel AM, Caron MG, Lefkowitz RJ. Mechanism of guanine nucleotide regulatory protein-mediated inhibition of adenylate cyclase. Studies with isolated subunits of transducin in a reconstituted system. The Journal of Biological Chemistry. 261: 9514-20. PMID 3013893 |
0.045 |
|
| 1978 |
Brown EM, Brennan MF, Hurwitz S, Windeck R, Marx SJ, Spiegel AM, Koehler JO, Gardner DG, Aurbach GD. Dispersed cells prepared from human parathyroid glands: distinct calcium sensitivity of adenomas vs. primary hyperplasia. The Journal of Clinical Endocrinology and Metabolism. 46: 267-75. PMID 750604 DOI: 10.1210/Jcem-46-2-267 |
0.045 |
|
| 1990 |
Morris D, McHugh-Sutkowski E, Moos M, Simonds WF, Spiegel AM, Seamon KB. Immunoprecipitation of adenylate cyclase with an antibody to a carboxyl-terminal peptide from Gs alpha. Biochemistry. 29: 9079-84. PMID 2125472 DOI: 10.1021/Bi00490A027 |
0.045 |
|
| 1992 |
Hermouet S, de Mazancourt P, Spiegel AM, Farquhar MG, Wilson BS. High level expression of transfected G protein alpha i3 subunit is required for plasma membrane targeting and adenylyl cyclase inhibition in NIH 3T3 fibroblasts. Febs Letters. 312: 223-8. PMID 1330693 DOI: 10.1016/0014-5793(92)80940-I |
0.045 |
|
| 1998 |
Agarwal SK, Debelenko LV, Kester MB, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Heppner C, Crabtree JS, Lubensky IA, Zhuang Z, Kim YS, Chandrasekharappa SC, Collins FS, Liotta LA, ... Spiegel AM, et al. Analysis of recurrent germline mutations in the MEN1 gene encountered in apparently unrelated families. Human Mutation. 12: 75-82. PMID 9671267 DOI: 10.1002/(Sici)1098-1004(1998)12:2<75::Aid-Humu1>3.0.Co;2-T |
0.044 |
|
| 1995 |
Buell JF, Fraker DL, Doppman JL, Shawker TH, Skarulis MC, Spiegel AM, Marx SJ, Alexander HR. High cervical intravagal hypercellular parathyroid gland as the etiology of severe persistent primary hyperparathyroidism. The American Surgeon. 61: 943-6. PMID 7486421 |
0.044 |
|
| 2015 |
Jee BD, Uttal DH, Spiegel A, Diamond J. Expert-novice differences in mental models of viruses, vaccines, and the causes of infectious disease. Public Understanding of Science (Bristol, England). 24: 241-56. PMID 23959975 DOI: 10.1177/0963662513496954 |
0.044 |
|
| 1985 |
Spiegel AM, Gierschik P, Levine MA, Downs RW. Clinical implications of guanine nucleotide-binding proteins as receptor-effector couplers. The New England Journal of Medicine. 312: 26-33. PMID 2856889 DOI: 10.1056/Nejm198501033120106 |
0.044 |
|
| 1987 |
Miller DL, Doppman JL, Shawker TH, Krudy AG, Norton JA, Vucich JJ, Morrish KA, Marx SJ, Spiegel AM, Aurbach GD. Localization of parathyroid adenomas in patients who have undergone surgery. Part I. Noninvasive imaging methods. Radiology. 162: 133-7. PMID 3538145 DOI: 10.1148/Radiology.162.1.3538145 |
0.043 |
|
| 1990 |
Jones TL, Spiegel AM. Isoprenylation of an inhibitory G protein alpha subunit occurs only upon mutagenesis of the carboxyl terminus. The Journal of Biological Chemistry. 265: 19389-92. PMID 2123186 |
0.043 |
|
| 1992 |
Butrynski JE, Jones TL, Backlund PS, Spiegel AM. Differential isoprenylation of carboxy-terminal mutants of an inhibitory G-protein alpha-subunit: neither farnesylation nor geranylgeranylation is sufficient for membrane attachment. Biochemistry. 31: 8030-5. PMID 1510988 DOI: 10.1021/Bi00149A037 |
0.043 |
|
| 1993 |
Degtyarev MY, Spiegel AM, Jones TL. The G protein alpha s subunit incorporates [3H]palmitic acid and mutation of cysteine-3 prevents this modification. Biochemistry. 32: 8057-61. PMID 8347607 DOI: 10.1021/Bi00083A001 |
0.043 |
|
| 1993 |
Hermouet S, Murakami T, Spiegel AM. Stable changes in expression or activation of G protein alpha i or alpha q subunits affect the expression of both beta 1 and beta 2 subunits. Febs Letters. 327: 183-8. PMID 8335108 DOI: 10.1016/0014-5793(93)80166-R |
0.043 |
|
| 1990 |
Spiegel AM, Simonds WF, Jones TL, Goldsmith PK, Unson CG. Antibodies as probes of G-protein receptor-effector coupling and of G-protein membrane attachment. Biochemical Society Symposium. 56: 61-9. PMID 2175191 |
0.043 |
|
| 1999 |
Libutti SK, Alexander HR, Bartlett DL, Sampson ML, Ruddel ME, Skarulis M, Marx SJ, Spiegel AM, Simmonds W, Remaley AT. Kinetic analysis of the rapid intraoperative parathyroid hormone assay in patients during operation for hyperparathyroidism. Surgery. 126: 1145-50; discussion . PMID 10598200 DOI: 10.1067/Msy.2099.101835 |
0.043 |
|
| 1981 |
Krudy AG, Doppman JL, Brennan MF, Marx SJ, Spiegel AM, Stock JL, Aurbach GD. The detection of mediastinal parathyroid glands by computed tomography, selective arteriography, and venous sampling: an analysis of 17 cases. Radiology. 140: 739-44. PMID 7280244 DOI: 10.1148/Radiology.140.3.7280244 |
0.043 |
|
| 1981 |
Spiegel AM, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie MF, Aurbach GD. Parathyroid function after parathyroidectomy: evaluation by measurement of urinary cAMP. Clinical Endocrinology. 15: 65-73. PMID 6273023 DOI: 10.1111/J.1365-2265.1981.Tb02749.X |
0.042 |
|
| 2010 |
Spiegel AM, Libutti SK. Future diagnostic and therapeutic trends in endocrine cancers. Seminars in Oncology. 37: 691-5. PMID 21167386 DOI: 10.1053/j.seminoncol.2010.10.020 |
0.042 |
|
| 1990 |
Friedman E, Bale AE, Marx SJ, Norton JA, Arnold A, Tu T, Aurbach GD, Spiegel AM. Genetic abnormalities in sporadic parathyroid adenomas. The Journal of Clinical Endocrinology and Metabolism. 71: 293-7. PMID 2199477 DOI: 10.1210/Jcem-71-2-293 |
0.042 |
|
| 1983 |
Attie MF, Gill JR, Stock JL, Spiegel AM, Downs RW, Levine MA, Marx SJ. Urinary calcium excretion in familial hypocalciuric hypercalcemia. Persistence of relative hypocalciuria after induction of hypoparathyroidism. The Journal of Clinical Investigation. 72: 667-76. PMID 6874959 DOI: 10.1172/Jci111016 |
0.042 |
|
| 1977 |
Kollarits CR, Moss ML, Cogan DG, Doppman JL, Di Chiro G, Cutler GB, Marx SJ, Spiegel AM. Scleral calcifications in hyperparathyroidism: demonstration by computed tomography. Journal of Computer Assisted Tomography. 1: 500-4. PMID 615231 DOI: 10.1097/00004728-197710000-00018 |
0.042 |
|
| 1987 |
Zick Y, Spiegel AM, Sagi-Eisenberg R. Insulin-like growth factor I receptors in retinal rod outer segments. The Journal of Biological Chemistry. 262: 10259-64. PMID 2956255 |
0.042 |
|
| 1993 |
Spiegel AM, Weinstein LS, Shenker A. Abnormalities in G protein-coupled signal transduction pathways in human disease. The Journal of Clinical Investigation. 92: 1119-25. PMID 8397218 DOI: 10.1172/Jci116680 |
0.042 |
|
| 1989 |
Murakami T, Rossiter K, Spiegel AM, Sacktor B. Identification of multiple Gi subtypes and a novel G protein in bovine kidney cortex. Biochemical Pharmacology. 38: 4502-5. PMID 2513812 DOI: 10.1016/0006-2952(89)90664-3 |
0.041 |
|
| 2017 |
Hill PW, McQuillan J, Talbert E, Spiegel A, Gauthier GR, Diamond J. Science Possible Selves and the Desire to be a Scientist: Mindsets, Gender Bias, and Confidence during Early Adolescence. Social Sciences (Basel, Switzerland). 6. PMID 29527360 DOI: 10.3390/Socsci6020055 |
0.041 |
|
| 1985 |
Gierschik P, Spiegel AM. Chymotrypsin selectively decreases forskolin stimulation of adenylate cyclase. Archives of Biochemistry and Biophysics. 242: 457-63. PMID 3904626 DOI: 10.1016/0003-9861(85)90230-9 |
0.041 |
|
| 1994 |
Billingsley KG, Fraker DL, Doppman JL, Norton JA, Shawker TH, Skarulis MC, Marx SJ, Spiegel AM, Alexander HR. Localization and operative management of undescended parathyroid adenomas in patients with persistent primary hyperparathyroidism. Surgery. 116: 982-9; discussion 98. PMID 7985106 |
0.041 |
|
| 1994 |
Degtyarev MY, Spiegel AM, Jones TL. The membrane localization of the G protein alpha s subunit is not dependent on its TENIR sequence or effector domain. Cellular Signalling. 6: 25-33. PMID 8011426 DOI: 10.1016/0898-6568(94)90058-2 |
0.041 |
|
| 1996 |
Wenkert D, Schoneberg T, Merendino JJ, Pena M, Vinitsky R, Goldsmith PK, Wess J, Spiegel AM. Expression and functional characterization of five v2 vasopressin receptor gene mutations identified in families with x-linked nephrogenic diabetes insipidus Journal of Investigative Medicine. 44: 225a. |
0.04 |
|
| 1987 |
Goldsmith P, Gierschik P, Milligan G, Unson CG, Vinitsky R, Malech HL, Spiegel AM. Antibodies directed against synthetic peptides distinguish between GTP-binding proteins in neutrophil and brain. The Journal of Biological Chemistry. 262: 14683-8. PMID 3117789 |
0.039 |
|
| 1997 |
Libutti SK, Bartlett DL, jaskowiak NT, Skarulis M, Marx SJ, Spiegel AM, Fraker DL, Doppman JL, Shawker TJ, Alexander HR. The role of thyroid resection during reoperation for persistent or recurrent hyperparathyroidism. Surgery. 122: 1183-7; discussion 1. PMID 9426436 DOI: 10.1016/S0039-6060(97)90225-7 |
0.039 |
|
| 1995 |
Varrault A, Pena MS, Goldsmith PK, Mithal A, Brown EM, Spiegel AM. Expression of G protein alpha-subunits in bovine parathyroid. Endocrinology. 136: 4390-6. PMID 7664659 DOI: 10.1210/Endo.136.10.7664659 |
0.039 |
|
| 2012 |
Spiegel AM, Hawkins M. 'Personalized medicine' to identify genetic risks for type 2 diabetes and focus prevention: can it fulfill its promise? Health Affairs (Project Hope). 31: 43-9. PMID 22232093 DOI: 10.1377/Hlthaff.2011.1054 |
0.039 |
|
| 1995 |
Shenker A, Chanson P, Weinstein LS, Chi P, Spiegel AM, Lomri A, Marie PJ. Osteoblastic cells derived from isolated lesions of fibrous dysplasia contain activating somatic mutations of the Gs alpha gene. Human Molecular Genetics. 4: 1675-6. PMID 8541861 DOI: 10.1093/Hmg/4.9.1675 |
0.039 |
|
| 1993 |
Hermouet S, de Mazancourt P, Spiegel AM. Mitogenic effects of pertussis toxin-sensitive G-protein alpha subunits: the mitogenic action of alpha i2 in NIH 3T3 cells is mimicked by alpha i1, but not alpha i3. Cellular Signalling. 5: 215-25. PMID 8388703 DOI: 10.1016/0898-6568(93)90072-T |
0.039 |
|
| 1990 |
Spiegel AM, Simonds WF, Jones TL, Goldsmith PK, Unson CG. Antibodies against synthetic peptides as probes of G protein structure and function. Society of General Physiologists Series. 45: 185-95. PMID 2116039 |
0.039 |
|
| 1989 |
Simonds WF, Collins RM, Spiegel AM, Brann MR. Membrane attachment of recombinant G-protein alpha-subunits in excess of beta gamma subunits in a eukaryotic expression system. Biochemical and Biophysical Research Communications. 164: 46-53. PMID 2508638 DOI: 10.1016/0006-291X(89)91680-X |
0.039 |
|
| 1997 |
Heppner C, Kester MB, Agarwal SK, Debelenko LV, Emmert-Buck MR, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, Kim YS, Saggar SK, Lubensky IA, Zhuang Z, ... ... Spiegel AM, et al. Somatic mutation of the MEN1 gene in parathyroid tumours. Nature Genetics. 16: 375-8. PMID 9241276 DOI: 10.1038/ng0897-375 |
0.039 |
|
| 1985 |
Cerione RA, Codina J, Kilpatrick BF, Staniszewski C, Gierschik P, Somers RL, Spiegel AM, Birnbaumer L, Caron MG, Lefkowitz RJ. Transducin and the inhibitory nucleotide regulatory protein inhibit the stimulatory nucleotide regulatory protein mediated stimulation of adenylate cyclase in phospholipid vesicle systems. Biochemistry. 24: 4499-503. PMID 3933556 DOI: 10.1021/Bi00338A002 |
0.038 |
|
| 1995 |
Chen CC, Premkumar A, Hill SC, Skarulis MC, Spiegel AM. Tc-99m sestamibi imaging of a hyperfunctioning parathyroid autograft with Doppler ultrasound and MRI correlation. Clinical Nuclear Medicine. 20: 222-5. PMID 7750215 DOI: 10.1097/00003072-199503000-00007 |
0.037 |
|
| 1988 |
Goldsmith P, Rossiter K, Carter A, Simonds W, Unson CG, Vinitsky R, Spiegel AM. Identification of the GTP-binding protein encoded by Gi3 complementary DNA. The Journal of Biological Chemistry. 263: 6476-9. PMID 3129425 |
0.037 |
|
| 1992 |
Murakami T, Simonds WF, Spiegel AM. Site-specific antibodies directed against G protein beta and gamma subunits: effects on alpha and beta gamma subunit interaction. Biochemistry. 31: 2905-11. PMID 1550816 DOI: 10.1021/Bi00126A009 |
0.037 |
|
| 2003 |
Spiegel AM. G protein-regulated signaling dysfunction in human disease: A personal historical perspective Journal of Investigative Medicine. 51: 192-193. DOI: 10.1136/Jim-51-04-20 |
0.037 |
|
| 1978 |
Spiegel AM, Doppman JL, Marx SJ, Brennan MF, Brown EM, Downs RW, Gardner DG, Attie M, Aurbach GD. Preoperative localization of abnormal parathyroid: neck massage versus arteriography and selective venous sampling. Annals of Internal Medicine. 89: 935-6. PMID 214001 DOI: 10.7326/0003-4819-89-6-935 |
0.036 |
|
| 1990 |
Jones TL, Simonds WF, Merendino JJ, Brann MR, Spiegel AM. Myristoylation of an inhibitory GTP-binding protein alpha subunit is essential for its membrane attachment. Proceedings of the National Academy of Sciences of the United States of America. 87: 568-72. PMID 2105488 DOI: 10.1073/Pnas.87.2.568 |
0.036 |
|
| 1998 |
Marx SJ, Agarwal SK, Kester MB, Heppner C, Kim YS, Emmert-Buck MR, Debelenko LV, Lubensky IA, Zhuang Z, Guru SC, Manickam P, Olufemi SE, Skarulis MC, Doppman JL, Alexander RH, ... ... Spiegel AM, et al. Germline and somatic mutation of the gene for multiple endocrine neoplasia type 1 (MEN1). Journal of Internal Medicine. 243: 447-53. PMID 9681842 DOI: 10.1046/J.1365-2796.1998.00348.X |
0.035 |
|
| 1980 |
Marx SJ, Stock JL, Attie MF, Downs RW, Gardner DG, Brown EM, Spiegel AM, Doppman JL, Brennan MF. Familial hypocalciuric hypercalcemia: recognition among patients referred after unsuccessful parathyroid exploration. Annals of Internal Medicine. 92: 351-6. PMID 7356229 DOI: 10.7326/0003-4819-92-3-351 |
0.035 |
|
| 1982 |
Krawietz W, Downs RW, Spiegel AM, Aurbach GD. Vanadate stimulates adenylate cyclase via the guanine nucleotide regulatory protein by a mechanism differing from that of fluoride. Biochemical Pharmacology. 31: 843-8. PMID 6282277 DOI: 10.1016/0006-2952(82)90472-5 |
0.034 |
|
| 1991 |
Shenker A, Goldsmith P, Unson CG, Spiegel AM. The G protein coupled to the thromboxane A2 receptor in human platelets is a member of the novel Gq family. Transactions of the Association of American Physicians. 104: 11-20. PMID 1845138 |
0.034 |
|
| 1978 |
Spiegel AM, Rosen SW, Weintraub BD, Marynick SP. Effect of intravenous pyridoxine on plasma prolactin in hyperprolactinemic subjects. The Journal of Clinical Endocrinology and Metabolism. 46: 686-8. PMID 755053 DOI: 10.1210/Jcem-46-4-686 |
0.034 |
|
| 1980 |
Downs RW, Spiegel AM, Singer M, Reen S, Aurbach GD. Fluoride stimulation of adenylate cyclase is dependent on the guanine nucleotide regulatory protein. The Journal of Biological Chemistry. 255: 949-54. PMID 6243302 |
0.033 |
|
| 2015 |
Spiegel AM. Young Islam: The new politics of religion in Morocco and the Arab World Young Islam: the New Politics of Religion in Morocco and the Arab World. 1-246. |
0.033 |
|
| 1988 |
McKenzie FR, Mullaney I, Unson CG, Spiegel AM, Milligan G. The use of anti-peptide antisera to probe interactions between receptors and guanine nucleotide binding proteins. Biochemical Society Transactions. 16: 434-7. PMID 2850230 DOI: 10.1042/Bst0160434 |
0.033 |
|
| 1992 |
Spiegel AM. Role of G proteins in signal transduction. Clinical Neuropharmacology. 15: 200A-201A. PMID 1498810 |
0.033 |
|
| 1982 |
Spiegel AM, Levine MA, Marx SJ, Aurbach GD. Pseudohypoparathyroidism: the molecular basis for hormone resistance--a retrospective. The New England Journal of Medicine. 307: 679-81. PMID 6287258 DOI: 10.1056/Nejm198209093071111 |
0.033 |
|
| 1983 |
Spiegel AM, Downs RW, Santora A, Marx SJ, Doppman J, Shull J. Persistent hyperparathyroidism caused by incomplete parathyroid resection and a hyperfunctioning parathyroid autograft. Jama. 250: 1896-8. PMID 6620488 DOI: 10.1001/jama.250.14.1896 |
0.032 |
|
| 1987 |
Cerione RA, Gierschik P, Staniszewski C, Benovic JL, Codina J, Somers R, Birnbaumer L, Spiegel AM, Lefkowitz RJ, Caron MG. Functional differences in the beta gamma complexes of transducin and the inhibitory guanine nucleotide regulatory protein. Biochemistry. 26: 1485-91. PMID 3032251 DOI: 10.1021/Bi00379A041 |
0.032 |
|
| 1978 |
Spiegel AM, Lopatin R, Peikin S, McCarthy D. Serum-prolactin in patients receiving chronic oral cimetidine. Lancet. 1: 881. PMID 76832 |
0.032 |
|
| 1993 |
Spiegel AM, Weinstein LS, Shenker A, Hermouet S, Merendino JJ. G proteins: from basic to clinical studies. Advances in Second Messenger and Phosphoprotein Research. 28: 37-46. PMID 8398416 |
0.032 |
|
| 1980 |
Nielsen TB, Downs RW, Spiegel AM. Restoration of guanine nucleotide- and fluoride-stimulated activity to an adenylate cyclase-deficient cell line with affinity-purified guanine nucleotide regulatory protein. The Biochemical Journal. 190: 439-43. PMID 6258568 DOI: 10.1042/Bj1900439 |
0.031 |
|
| 2021 |
Diamond J, Spiegel A, Hill TW, VanWormer E, Gaiashkibos J, Hall B, Sutherlen A, McQuillan J. Developing Pandemic Comics for Youth Audiences. Journal of Stem Outreach. 4. PMID 34532652 DOI: 10.15695/jstem/v4i2.03 |
0.031 |
|
| 1994 |
Wenkert D, Merendino JJ, Shenker A, Thambi N, Robertson GL, Moses AM, Spiegel AM. Novel mutations in the V2 vasopressin receptor gene of patients with X-linked nephrogenic diabetes insipidus. Human Molecular Genetics. 3: 1429-30. PMID 7987330 DOI: 10.1093/Hmg/3.8.1429 |
0.031 |
|
| 1980 |
Spiegel AM, Eastman ST, Attie MF, Downs RW, Levine MA, Marx SJ, Stock JL, Saxe AW, Brennan MF, Aurbach GD. Intraoperative measurements of urinary cyclic AMP to guide surgery for primary hyperparathyroidism. The New England Journal of Medicine. 303: 1457-60. PMID 6253789 DOI: 10.1056/Nejm198012183032505 |
0.031 |
|
| 2001 |
Hu J, Reyes-Cruz G, Goldsmith PK, Spiegel AM. The Venus's-flytrap and cysteine-rich domains of the human Ca2+ receptor are not linked by disulfide bonds. The Journal of Biological Chemistry. 276: 6901-4. PMID 11238442 DOI: 10.1074/Jbc.C000865200 |
0.03 |
|
| 1989 |
Daniel-Issakani S, Spiegel AM, Strulovici B. Lipopolysaccharide response is linked to the GTP binding protein, Gi2, in the promonocytic cell line U937. The Journal of Biological Chemistry. 264: 20240-7. PMID 2511200 |
0.029 |
|
| 2001 |
Alavi A, Chamberlain J, Cherrington AD, Convit A, Craft S, Cryer PE, Davis SN, Davison S, De Leon M, DeRosa M, Drucker D, Albert M, Evans M, Feldman E, Fischbach GD, ... ... Spiegel AM, et al. Workshop on hypoglycemia and the brain Diabetes Technology and Therapeutics. 3: 469-516. DOI: 10.1089/15209150152607259 |
0.029 |
|
| 1984 |
Krudy AG, Doppman JL, Marx SJ, Norton JA, Spiegel AM, Santora AC, Aurbach GD. Parathyroid aspiration directed by angiography: an alternative to venous sampling. Radiology. 152: 207-8. PMID 6729114 DOI: 10.1148/Radiology.152.1.6729114 |
0.028 |
|
| 1986 |
Milligan G, Gierschik P, Spiegel AM, Klee WA. The GTP-binding regulatory proteins of neuroblastoma x glioma, NG108-15, and glioma, C6, cells. Immunochemical evidence of a pertussis toxin substrate that is neither Ni nor No. Febs Letters. 195: 225-30. PMID 3080332 |
0.027 |
|
| 1985 |
Doppman JL, Shawker TH, Krudy AG, Miller DL, Marx SJ, Spiegel AM, Norton JA, Brennan MF, Schaaf M, Aurbach GD. Parathymic parathyroid: CT, US, and angiographic findings. Radiology. 157: 419-23. PMID 3901107 DOI: 10.1148/Radiology.157.2.3901107 |
0.026 |
|
| 1992 |
Spiegel AM. Heterotrimeric GTP-binding proteins: an expanding family of signal transducers. Medicinal Research Reviews. 12: 55-71. PMID 1738245 DOI: 10.1002/Med.2610120105 |
0.026 |
|
| 2013 |
Spiegel AM. The stem cell wars: a dispatch from the front. Transactions of the American Clinical and Climatological Association. 124: 94-110. PMID 23874014 |
0.024 |
|
| 1980 |
Attie MF, Brown EM, Gardner DG, Spiegel AM, Aurbach GD. Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion. Endocrinology. 107: 1776-81. PMID 7428692 DOI: 10.1210/Endo-107-6-1776 |
0.024 |
|
| 2006 |
Spiegel AM, Nabel EG. NIH research on obesity and type 2 diabetes: providing the scientific evidence base for actions to improve health. Nature Medicine. 12: 67-9. PMID 16397572 DOI: 10.1038/Nm0106-67 |
0.024 |
|
| 2004 |
Spiegel AM. Focus on hereditary endocrine neoplasia. Cancer Cell. 6: 327-32. PMID 15488756 DOI: 10.1016/J.Ccr.2004.09.023 |
0.024 |
|
| 2005 |
Spiegel AM, Alving BM. Executive summary of the Strategic Plan for National Institutes of Health Obesity Research. The American Journal of Clinical Nutrition. 82: 211S-214S. PMID 16002822 DOI: 10.1093/Ajcn/82.1.221S |
0.023 |
|
| 1977 |
Gerner RH, Post RM, Spiegel AM, Murphy DL. Effects of parathormone and lithium treatment on calcium and mood in depressed patients. Biological Psychiatry. 12: 145-51. PMID 836922 |
0.022 |
|
| 2001 |
Valle MA, Kester MB, Burns AL, Marx SJ, Spiegel AM, Shiloach J. Production and purification of human menin from Drosophila melanogaster S2 cells using stirred tank reactor. Cytotechnology. 35: 127-35. PMID 19003289 DOI: 10.1023/A:1017586523710 |
0.022 |
|
| 1984 |
Krudy AG, Doppman JL, Miller DL, Norton JA, Marx SJ, Spiegel AM, Santora AC, Aurbach GD, Schaaf M. Detection of mediastinal parathyroid glands by nonselective digital arteriography. Ajr. American Journal of Roentgenology. 142: 693-5. PMID 6608224 DOI: 10.2214/Ajr.142.4.693 |
0.022 |
|
| 1988 |
Rotrosen D, Gallin JI, Spiegel AM, Malech HL. Subcellular localization of Gi alpha in human neutrophils. The Journal of Biological Chemistry. 263: 10958-64. PMID 3134354 |
0.021 |
|
| 2024 |
Fung VSC, Aldred J, Arroyo MP, Bergquist F, Boon AJW, Bouchard M, Bray S, Dhanani S, Facheris MF, Fisseha N, Freire-Alvarez E, Hauser RA, Jeong A, Jia J, Kukreja P, ... ... Spiegel AM, et al. Continuous subcutaneous foslevodopa/foscarbidopa infusion for the treatment of motor fluctuations in Parkinson's disease: Considerations for initiation and maintenance. Clinical Parkinsonism & Related Disorders. 10: 100239. PMID 38419617 DOI: 10.1016/j.prdoa.2024.100239 |
0.02 |
|
| 2023 |
Aldred J, Freire-Alvarez E, Amelin AV, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C, Chaudhuri KR, Criswell SR, Danielsen EH, Gandor F, Jia J, Kimber TE, ... ... Spiegel AM, et al. Correction: Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson's Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study. Neurology and Therapy. PMID 37817017 DOI: 10.1007/s40120-023-00554-w |
0.02 |
|
| 1982 |
Saxe AW, Spiegel AM, Marx SJ, Brennan MF. Deferred parathyroid autografts with cryopreserved tissue after reoperative parathyroid surgery. Archives of Surgery (Chicago, Ill. : 1960). 117: 538-43. PMID 7073473 DOI: 10.1001/archsurg.1982.01380290010003 |
0.019 |
|
| 1999 |
Spiegel AM. Citation for the 1999 Monsanto Clinical Investigator Lecture Award of the Endocrine Society to Dr. Stephen J. Marx. Endocrine Reviews. 20: 590-1. PMID 10453362 |
0.018 |
|
| 2023 |
Aldred J, Freire-Alvarez E, Amelin AV, Antonini A, Bergmans B, Bergquist F, Bouchard M, Budur K, Carroll C, Chaudhuri KR, Criswell SR, Danielsen EH, Gandor F, Jia J, Kimber TE, ... ... Spiegel AM, et al. Continuous Subcutaneous Foslevodopa/Foscarbidopa in Parkinson's Disease: Safety and Efficacy Results From a 12-Month, Single-Arm, Open-Label, Phase 3 Study. Neurology and Therapy. PMID 37632656 DOI: 10.1007/s40120-023-00533-1 |
0.017 |
|
| 2005 |
Elson CO, Ballew M, Barnard JA, Bernstein SJ, Check IJ, Cohen MB, Fazio S, Johanson JF, Lindor NM, Montgomery E, Richardson LH, Rogers D, Vijan S, Bushara KO, Case S, ... ... Spiegel AM, et al. National Institutes of Health Consensus Development Conference statement on Celiac Disease, June 28-30, 2004 Gastroenterology. 128: S1-S9. PMID 15825115 DOI: 10.1053/j.gastro.2005.02.007 |
0.017 |
|
| 2024 |
Chaudhuri KR, Facheris MF, Bergmans B, Bergquist F, Criswell SR, Jia J, Kukreja P, Mukai Y, Spiegel AM, Gupta R, Bergmann L, Pahwa R. Improved Sleep Correlates with Improved Quality of Life and Motor Symptoms with Foslevodopa/Foscarbidopa. Movement Disorders Clinical Practice. PMID 38465885 DOI: 10.1002/mdc3.14018 |
0.015 |
|
| 2011 |
Spiegel AM, Libutti SK. Targeted therapies: Good news for advanced-stage pancreatic neuroendocrine tumors. Nature Reviews. Clinical Oncology. 8: 258-9. PMID 21448150 DOI: 10.1038/nrclinonc.2011.50 |
0.015 |
|
| 2019 |
Matuk C, Hurwich T, Spiegel A, Diamond J. How do teachers use comics to promote engagement, equity, and diversity in science classrooms? Research in Science Education. 51: 685-732. PMID 34024960 DOI: 10.1007/s11165-018-9814-8 |
0.014 |
|
| 1981 |
Marx SJ, Attie MF, Levine MA, Spiegel AM, Downs RW, Lasker RD. The hypocalciuric or benign variant of familial hypercalcemia: clinical and biochemical features in fifteen kindreds. Medicine. 60: 397-412. PMID 7311809 DOI: 10.1097/00005792-198111000-00002 |
0.011 |
|
| 1997 |
Spiegel AM. Citation for the 1997 Gerald D. Aurbach Lecture Award of The Endocrine Society to Edward M. Brown. Endocrine Reviews. 18: 616-7. PMID 9267769 |
0.01 |
|
| 2015 |
Levine AS, Alpern RJ, Andrews NC, Antman K, Balser JR, Berg JM, Davis PB, Fitz JG, Golden RN, Goldman L, Jameson JL, Lee VS, Polonsky KS, Rappley MD, Reece EA, ... ... Spiegel AM, et al. Research in academic medical centers: two threats to sustainable support. Science Translational Medicine. 7: 289fs22. PMID 26019216 DOI: 10.1126/Scitranslmed.Aac5200 |
0.01 |
|
| 2013 |
Weinstein LS, Collins MT, Spiegel AM. Gsα, Pseudohypoparathyroidism, Fibrous Dysplasia, and McCune-Albright Syndrome Genetics of Bone Biology and Skeletal Disease. 425-440. DOI: 10.1016/B978-0-12-387829-8.00027-5 |
0.01 |
|
| 2002 |
Spiegel AD, Spiegel AM. Abraham and Mary Lincoln: Insanity in and out of the courtroom American Journal of Forensic Psychiatry. 23: 53-69. |
0.01 |
|
| 2000 |
Spiegel AD, Spiegel AM. For the first time in a U.S. Court: A murderer's temporary insanity plea American Journal of Forensic Psychiatry. 21: 3-30. |
0.01 |
|
| 1994 |
Doppman JL, Shawker TH, Fraker DL, Alexander HR, Skarulis MC, Lack EE, Spiegel AM. Parathyroid adenoma within the vagus nerve. Ajr. American Journal of Roentgenology. 163: 943-5. PMID 8092040 DOI: 10.2214/Ajr.163.4.8092040 |
0.01 |
|
| 1993 |
Spiegel AM. Gerald D. Aurbach, 1927-1991 Vitamins and Hormones. 47: xi-xii. DOI: 10.1016/S0083-6729(08)60443-4 |
0.01 |
|
| 1992 |
Spiegel AD, Spiegel AM. Was it murder or insanity? Reactions to a successful paroxysmal insanity plea in 1865. Women & Health. 18: 69-86. PMID 1632102 DOI: 10.1300/J013v18n02_05 |
0.01 |
|
| 1992 |
Potts JT, Spiegel AM. In memoriam Gerald D. Aurbach. Molecular Endocrinology (Baltimore, Md.). 6: 1982-4. PMID 1480184 DOI: 10.1210/mend.6.11.1480184 |
0.01 |
|
| 1992 |
Potts JT, Spiegel AM. In memoriam Gerald D. Aurbach. The Journal of Clinical Endocrinology and Metabolism. 75: 1386-8. PMID 1430101 DOI: 10.1210/jcem.75.5.1430101 |
0.01 |
|
| 1980 |
Marx SJ, Aurbach GD, Spiegel AM. Incidence of primary hyperparathyroidism. The New England Journal of Medicine. 302: 1313. PMID 7366701 |
0.01 |
|
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