Year |
Citation |
Score |
2019 |
Kwon OH, Cho YY, Kim TW, Chung S. O-GlcNAcylation of Amyloid-β Protein Precursor by Insulin Signaling Reduces Amyloid-β Production. Journal of Alzheimer's Disease : Jad. PMID 31156159 DOI: 10.3233/Jad-190060 |
0.315 |
|
2019 |
Cho YY, Kwon OH, Park MK, Kim TW, Chung S. Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein. Plos One. 14: e0210535. PMID 30682043 DOI: 10.1371/Journal.Pone.0210535 |
0.365 |
|
2016 |
Finan GM, Realubit R, Chung S, Lütjohann D, Wang N, Cirrito JR, Karan C, Kim TW. Bioactive Compound Screen for Pharmacological Enhancers of Apolipoprotein E in Primary Human Astrocytes. Cell Chemical Biology. PMID 27889409 DOI: 10.1016/J.Chembiol.2016.10.015 |
0.318 |
|
2016 |
Cho JH, Ryu JK, Song SY, Hwang JH, Lee DK, Woo SM, Joo YE, Jeong S, Lee SO, Park BK, Cheon YK, Han J, Kim TN, Lee JK, Moon SH, ... ... Kim TH, et al. Prognostic Validity of the American Joint Committee on Cancer and the European Neuroendocrine Tumors Staging Classifications for Pancreatic Neuroendocrine Tumors: A Retrospective Nationwide Multicenter Study in South Korea. Pancreas. PMID 26765964 DOI: 10.1097/MPA.0000000000000586 |
0.487 |
|
2016 |
McIntire L, Hwang J, Gong G, Rinderspacher A, Deng S, Landry D, Kim T. DT-01-01: Plasma Membrane Monoamine Transporter Modulates Bace1 Activity Alzheimer's & Dementia. 12: P1134-P1134. DOI: 10.1016/J.Jalz.2016.07.007 |
0.567 |
|
2015 |
Chun YS, Kwon OH, Oh HG, Kim TW, McIntire LB, Park MK, Chung S. Threonine 576 residue of amyloid-β precursor protein regulates its trafficking and processing. Biochemical and Biophysical Research Communications. PMID 26471307 DOI: 10.1016/J.Bbrc.2015.10.037 |
0.383 |
|
2015 |
Chun YS, Park Y, Oh HG, Kim TW, Yang HO, Park MK, Chung S. O-GlcNAcylation promotes non-amyloidogenic processing of amyloid-β protein precursor via inhibition of endocytosis from the plasma membrane. Journal of Alzheimer's Disease : Jad. 44: 261-75. PMID 25208619 DOI: 10.3233/Jad-140096 |
0.353 |
|
2014 |
McIntire LB, Lee KI, Chang-Ileto B, Di Paolo G, Kim TW. Screening assay for small-molecule inhibitors of synaptojanin 1, a synaptic phosphoinositide phosphatase. Journal of Biomolecular Screening. 19: 585-94. PMID 24186361 DOI: 10.1177/1087057113510177 |
0.356 |
|
2013 |
An K, Klyubin I, Kim Y, Jung JH, Mably AJ, O'Dowd ST, Lynch T, Kanmert D, Lemere CA, Finan GM, Park JW, Kim TW, Walsh DM, Rowan MJ, Kim JH. Exosomes neutralize synaptic-plasticity-disrupting activity of Aβ assemblies in vivo. Molecular Brain. 6: 47. PMID 24284042 DOI: 10.1186/1756-6606-6-47 |
0.465 |
|
2013 |
McIntire LB, Landman N, Kang MS, Finan GM, Hwang JC, Moore AZ, Park LS, Lin CS, Kim TW. Phenotypic assays for β-amyloid in mouse embryonic stem cell-derived neurons. Chemistry & Biology. 20: 956-67. PMID 23890013 DOI: 10.1016/J.Chembiol.2013.06.005 |
0.725 |
|
2013 |
Kang MS, Baek SH, Chun YS, Moore AZ, Landman N, Berman D, Yang HO, Morishima-Kawashima M, Osawa S, Funamoto S, Ihara Y, Di Paolo G, Park JH, Chung S, Kim TW. Modulation of lipid kinase PI4KIIα activity and lipid raft association of presenilin 1 underlies γ-secretase inhibition by ginsenoside (20S)-Rg3. The Journal of Biological Chemistry. 288: 20868-82. PMID 23723072 DOI: 10.1074/Jbc.M112.445734 |
0.754 |
|
2012 |
McIntire LB, Berman DE, Myaeng J, Staniszewski A, Arancio O, Di Paolo G, Kim TW. Reduction of synaptojanin 1 ameliorates synaptic and behavioral impairments in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15271-6. PMID 23115165 DOI: 10.1523/Jneurosci.2034-12.2012 |
0.363 |
|
2011 |
Paolo GD, Kim T. Linking lipids to Alzheimer's disease: cholesterol and beyond Nature Reviews Neuroscience. 12: 284-296. PMID 21448224 DOI: 10.1038/Nrn3012 |
0.318 |
|
2011 |
Finan GM, Okada H, Kim TW. BACE1 retrograde trafficking is uniquely regulated by the cytoplasmic domain of sortilin. The Journal of Biological Chemistry. 286: 12602-16. PMID 21245145 DOI: 10.1074/Jbc.M110.170217 |
0.587 |
|
2010 |
Oliveira TG, Chan RB, Tian H, Laredo M, Shui G, Staniszewski A, Zhang H, Wang L, Kim TW, Duff KE, Wenk MR, Arancio O, Di Paolo G. Phospholipase d2 ablation ameliorates Alzheimer's disease-linked synaptic dysfunction and cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16419-28. PMID 21147981 DOI: 10.1523/Jneurosci.3317-10.2010 |
0.373 |
|
2010 |
Okada H, Zhang W, Peterhoff C, Hwang JC, Nixon RA, Ryu SH, Kim TW. Proteomic identification of sorting nexin 6 as a negative regulator of BACE1-mediated APP processing. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 24: 2783-94. PMID 20354142 DOI: 10.1096/Fj.09-146357 |
0.703 |
|
2008 |
Lee SS, Shin JH, Woo CW, Hwang JC, Park CS, Kim HJ, Kim EY, Kim TH, Song HY. A new model of tracheal stenosis in dogs using combined bronchoscopic electrocautery and ethanol injection. Journal of Vascular and Interventional Radiology : Jvir. 19: 764-9. PMID 18440467 DOI: 10.1016/j.jvir.2008.01.025 |
0.494 |
|
2008 |
Berman DE, Dall'Armi C, Voronov SV, McIntire LB, Zhang H, Moore AZ, Staniszewski A, Arancio O, Kim TW, Di Paolo G. Oligomeric amyloid-beta peptide disrupts phosphatidylinositol-4,5-bisphosphate metabolism. Nature Neuroscience. 11: 547-54. PMID 18391946 DOI: 10.1038/Nn.2100 |
0.372 |
|
2006 |
Landman N, Jeong SY, Shin SY, Voronov SV, Serban G, Kang MS, Park MK, Di Paolo G, Chung S, Kim TW. Presenilin mutations linked to familial Alzheimer's disease cause an imbalance in phosphatidylinositol 4,5-bisphosphate metabolism. Proceedings of the National Academy of Sciences of the United States of America. 103: 19524-9. PMID 17158800 DOI: 10.1073/Pnas.0604954103 |
0.749 |
|
2006 |
Hwang JC, Okada H, Pandya K, Wang J, Lichtenthaler S, Kim T. P2-043: Developing cell-based assays for detection and quantification of the β-site-cleaved secreted APP ectodomain (sAPPβ) Alzheimer's & Dementia. 2: S244-S245. DOI: 10.1016/J.Jalz.2006.05.880 |
0.655 |
|
2006 |
Kim T, Landman N. O3-03-04 Alzheimer's & Dementia. 2: S57. DOI: 10.1016/J.Jalz.2006.05.208 |
0.704 |
|
2006 |
Finan GM, Hwang JC, Okada H, Small SA, Kim T. P4-065: Sortilin modulates the trafficking and activity of BACE1 Alzheimer's & Dementia. 2: S532-S532. DOI: 10.1016/J.Jalz.2006.05.1803 |
0.66 |
|
2005 |
Small SA, Kent K, Pierce A, Leung C, Kang MS, Okada H, Honig L, Vonsattel JP, Kim TW. Model-guided microarray implicates the retromer complex in Alzheimer's disease. Annals of Neurology. 58: 909-19. PMID 16315276 DOI: 10.1002/Ana.20667 |
0.555 |
|
2004 |
Landman N, Kim TW. Got RIP? Presenilin-dependent intramembrane proteolysis in growth factor receptor signaling. Cytokine & Growth Factor Reviews. 15: 337-51. PMID 15450250 DOI: 10.1016/J.Cytogfr.2004.04.001 |
0.751 |
|
2003 |
Jung KM, Tan S, Landman N, Petrova K, Murray S, Lewis R, Kim PK, Kim DS, Ryu SH, Chao MV, Kim TW. Regulated intramembrane proteolysis of the p75 neurotrophin receptor modulates its association with the TrkA receptor. The Journal of Biological Chemistry. 278: 42161-9. PMID 12913006 DOI: 10.1074/Jbc.M306028200 |
0.757 |
|
2003 |
Sun Y, Yao J, Kim TW, Tall AR. Expression of liver X receptor target genes decreases cellular amyloid beta peptide secretion. The Journal of Biological Chemistry. 278: 27688-94. PMID 12754201 DOI: 10.1074/Jbc.M300760200 |
0.389 |
|
2001 |
Hwang JC, Song HY, Kang SG, Suh JH, Ko GY, Lee DH, Kim TH, Jeong YK, Lee JH. Covered retrievable tracheobronchial hinged stent: an experimental study in dogs. Journal of Vascular and Interventional Radiology : Jvir. 12: 1429-36. PMID 11742020 |
0.482 |
|
2000 |
Tesco G, Melikian A, Kim T, Kovacs DM, Tanzi RE. Effects of staurosporine-mediated cell death on aβproduction and caspase-mediated cleavage of amyloid precursor protein and presenilins Neurobiology of Aging. 21: 68. DOI: 10.1016/S0197-4580(00)82528-2 |
0.306 |
|
2000 |
Cheng I, Yoo AS, Pack-Chung E, Park S, Saunders AJ, Tanzi RE, Kim T. Inhibition of capacitative calcium entry pathway potentiates presenilin-associated ‘-secretase activities of the amyloid β-precursor protein and Notch Neurobiology of Aging. 21: 118. DOI: 10.1016/S0197-4580(00)82331-3 |
0.309 |
|
1999 |
Saunders AJ, Kim T, Tanzi RE. BACE Maps to Chromosome 11 and a BACE Homolog, BACE2, Reside in the Obligate Down Syndrome Region of Chromosome 21 Science. 286: 1255-1255. DOI: 10.1126/Science.286.5443.1255A |
0.326 |
|
1997 |
Kim TW, Tanzi RE. Presenilins and Alzheimer's disease. Current Opinion in Neurobiology. 7: 683-8. PMID 9384549 DOI: 10.1016/S0959-4388(97)80089-X |
0.344 |
|
1997 |
Kim TW, Pettingell WH, Jung YK, Kovacs DM, Tanzi RE. Alternative cleavage of Alzheimer-associated presenilins during apoptosis by a caspase-3 family protease. Science (New York, N.Y.). 277: 373-6. PMID 9219695 DOI: 10.1126/Science.277.5324.373 |
0.312 |
|
1997 |
Kim TW, Pettingell WH, Hallmark OG, Moir RD, Wasco W, Tanzi RE. Endoproteolytic cleavage and proteasomal degradation of presenilin 2 in transfected cells. The Journal of Biological Chemistry. 272: 11006-10. PMID 9110991 DOI: 10.1074/Jbc.272.17.11006 |
0.313 |
|
1996 |
Tanzi RE, Kovacs DM, Kim TW, Moir RD, Guenette SY, Wasco W. The gene defects responsible for familial Alzheimer's disease. Neurobiology of Disease. 3: 159-68. PMID 8980016 DOI: 10.1006/Nbdi.1996.0016 |
0.345 |
|
1996 |
Irizarry MC, Kim TW, McNamara M, Tanzi RE, George JM, Clayton DF, Hyman BT. Characterization of the precursor protein of the non-A beta component of senile plaques (NACP) in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 55: 889-95. PMID 8759778 DOI: 10.1097/00005072-199608000-00004 |
0.353 |
|
1994 |
Kanno H, Kitawaki J, Maeda K, Kim T, Noguchi T, Yamamoto T, Okada H. [Regulation of aromatase in human choriocarcinoma cells]. Nihon Sanka Fujinka Gakkai Zasshi. 46: 449-56. PMID 8182306 |
0.464 |
|
1993 |
Kitawaki J, Kim T, Kanno H, Noguchi T, Yamamoto T, Okada H. Growth suppression of MCF-7 human breast cancer cells by aromatase inhibitors: a new system for aromatase inhibitor screening. The Journal of Steroid Biochemistry and Molecular Biology. 44: 667-70. PMID 8476780 |
0.44 |
|
1993 |
Noguchi T, Kitawaki J, Tamura T, Kim T, Kanno H, Yamamoto T, Okada H. Relationship between aromatase activity and steroid receptor levels in ovarian tumors from postmenopausal women. The Journal of Steroid Biochemistry and Molecular Biology. 44: 657-60. PMID 8476778 |
0.447 |
|
1993 |
Noguchi T, Kitawaki J, Tamura T, Kanno H, Kim T, Maeda K, Yamamoto T, Okada H. [Relationship among aromatase activity, estrogen receptor and progesterone receptor in ovarian tumors from postmenopausal women]. Nihon Sanka Fujinka Gakkai Zasshi. 45: 1123-8. PMID 8245591 |
0.436 |
|
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