Ross A. Cardarelli, PhD - Publications

Affiliations: 
2002-2006 University of Connecticut, Storrs, CT, United States 
 2006-2013 Neuroscience University of Maryland School of Medicine, Baltimore, MD, United States 
 2013-2019 Neuroscience Tufts University, Boston 
 2019- Caraway Therapeutics 
Area:
Electrophysiology, schizophrenia, dopamine, GABA, chloride homeostasis, epilepsy, neurodevelopmental/neurodegenerative disorders

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Jarvis R, Josephine Ng SF, Nathanson AJ, Cardarelli RA, Abiraman K, Wade F, Evans-Strong A, Fernandez-Campa MP, Deeb TZ, Smalley JL, Jamier T, Gurrell IK, McWilliams L, Kawatkar A, Conway LC, et al. Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice. Cell Reports. Medicine. 100957. PMID 36889319 DOI: 10.1016/j.xcrm.2023.100957  0.621
2021 Kontou G, Josephine Ng SF, Cardarelli RA, Howden JH, Choi C, Ren Q, Rodriguez Santos MA, Bope CE, Dengler JS, Kelly MR, Davies PA, Kittler JT, Brandon NJ, Moss SJ, Smalley JL. KCC2 is required for the survival of mature neurons but not for their development. The Journal of Biological Chemistry. 100364. PMID 33539918 DOI: 10.1016/j.jbc.2021.100364  0.682
2018 Cardarelli RA, Martin R, Jaaro-Peled H, Sawa A, Powell EM, O'Donnell P. Dominant-Negative DISC1 Alters the Dopaminergic Modulation of Inhibitory Interneurons in the Mouse Prefrontal Cortex. Molecular Neuropsychiatry. 4: 20-29. PMID 29998115 DOI: 10.1159/000488030  0.444
2018 Kelley MR, Cardarelli RA, Smalley JL, Ollerhead TA, Andrew PM, Brandon NJ, Deeb TZ, Moss SJ. Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy. Ebiomedicine. PMID 29884458 DOI: 10.1016/j.ebiom.2018.05.029  0.675
2018 Kelley MR, Cardarelli RA, Smalley JL, Ollerhead TA, Andrew PM, Brandon NJ, Deeb TZ, Moss SJ. Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy Ebiomedicine. 32: 62-71. PMID 29884458 DOI: 10.1016/j.ebiom.2018.05.029  0.426
2017 Cardarelli RA, Jones K, Pisella LI, Wobst HJ, McWilliams LJ, Sharpe PM, Burnham MP, Baker DJ, Chudotvorova I, Guyot J, Silayeva L, Morrow DH, Dekker N, Zicha S, Davies PA, et al. The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity. Nature Medicine. 23: 1394-1396. PMID 29216042 DOI: 10.1038/nm.4442  0.568
2017 Agez M, Schultz P, Medina I, Baker DJ, Burnham MP, Cardarelli RA, Conway LC, Garnier K, Geschwindner S, Gunnarsson A, McCall EJ, Frechard A, Audebert S, Deeb TZ, Moss SJ, et al. Molecular architecture of potassium chloride co-transporter KCC2. Scientific Reports. 7: 16452. PMID 29184062 DOI: 10.1038/s41598-017-15739-1  0.625
2017 Agez M, Schultz P, Medina I, Baker DJ, Burnham MP, Cardarelli RA, Conway LC, Garnier K, Geschwindner S, Gunnarsson A, McCall EJ, Frechard A, Audebert S, Deeb TZ, Moss SJ, et al. Molecular architecture of potassium chloride co-transporter KCC2. Scientific Reports. PMID 29184062 DOI: 10.1038/s41598-017-15739-1  0.341
2017 Conway LC, Cardarelli RA, Moore YE, Jones K, McWilliams LJ, Baker DJ, Burnham MP, Bürli RW, Wang Q, Brandon NJ, Moss SJ, Deeb TZ. N-ethylmaleimide increases KCC2 activity by modulating transporter phosphorylation. The Journal of Biological Chemistry. PMID 29092909 DOI: 10.1074/jbc.M117.817841  0.645
2017 Conway LC, Cardarelli RA, Moore YE, Jones K, McWilliams LJ, Baker DJ, Burnham MP, Bürli RW, Wang Q, Brandon NJ, Moss SJ, Deeb TZ. N-Ethylmaleimide increases KCC2 cotransporter activity by modulating transporter phosphorylation Journal of Biological Chemistry. PMID 29092909 DOI: 10.1074/jbc.M117.817841  0.379
2017 Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, Deeb TZ, Srivastava DP, Tyagarajan SK, Pangalos MN, Triller A, Maguire J, Brandon NJ, Moss SJ. Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078280 DOI: 10.1073/Pnas.1705075114  0.671
2017 Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, Deeb TZ, Srivastava DP, Tyagarajan SK, Pangalos MN, Triller A, Maguire J, Brandon NJ, Moss SJ. Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses Pnas. PMID 29078280 DOI: 10.1073/pnas.1705075114  0.418
2015 Sivakumaran S, Cardarelli RA, Maguire J, Kelley MR, Silayeva L, Morrow DH, Mukherjee J, Moore YE, Mather RJ, Duggan ME, Brandon NJ, Dunlop J, Zicha S, Moss SJ, Deeb TZ. Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8291-6. PMID 26019342 DOI: 10.1523/Jneurosci.5205-14.2015  0.695
2015 Sivakumaran S, Cardarelli RA, Maguire J, Kelley MR, Silayeva L, Morrow DH, Mukherjee J, Moore YE, Mather RJ, Duggan ME, Brandon NJ, Dunlop J, Zicha S, Moss SJ, Deeb TZ. Selective inhibition of KCC2 leads to hyperexcitability and epileptiform discharges in hippocampal slices and in vivo Journal of Neuroscience. PMID 26019342 DOI: 10.1523/JNEUROSCI.5205-14.2015  0.506
2015 Kano S, Yuan M, Cardarelli RA, Maegawa G, Higurashi N, Gaval-Cruz M, Wilson AM, Tristan C, Kondo MA, Chen Y, Koga M, Obie C, Ishizuka K, Seshadri S, Srivastava R, et al. Clinical utility of neuronal cells directly converted from fibroblasts of patients for neuropsychiatric disorders: studies of lysosomal storage diseases and channelopathy. Current Molecular Medicine. 15: 138-45. PMID 25732146 DOI: 10.2174/1566524015666150303110300  0.531
2012 Cardarelli RA, Sawa A, O'Donnell P. Poster #80 DISRUPTION OF PREFRONTAL FAST-SPIKING INTERNEURONS IN THE DISC1-DN MOUSE MODEL OF SCHIZOPHRENIA Schizophrenia Research. 136: S120. DOI: 10.1016/S0920-9964(12)70395-X  0.458
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