Jeffrey Simms - Publications

Affiliations: 
Ernest Gallo Clinic and Research Center, Emeryville, CA, United States 

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Year Citation  Score
Low-probability matches (unlikely to be authored by this person)
2007 Dayas CV, Liu X, Simms JA, Weiss F. Distinct patterns of neural activation associated with ethanol seeking: effects of naltrexone. Biological Psychiatry. 61: 979-89. PMID 17098214 DOI: 10.1016/J.Biopsych.2006.07.034  0.299
2016 Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. Defining the role of corticotropin releasing factor binding protein in alcohol consumption. Translational Psychiatry. 6: e953. PMID 27845775 DOI: 10.1038/Tp.2016.208  0.256
2010 Steensland P, Simms JA, Nielsen CK, Holgate J, Bito-Onon JJ, Bartlett SE. The neurokinin 1 receptor antagonist, ezlopitant, reduces appetitive responding for sucrose and ethanol. Plos One. 5. PMID 20824145 DOI: 10.1371/Journal.Pone.0012527  0.233
2008 Nielsen CK, Simms JA, Pierson HB, Li R, Saini SK, Ananthan S, Bartlett SE. A novel delta opioid receptor antagonist, SoRI-9409, produces a selective and long-lasting decrease in ethanol consumption in heavy-drinking rats. Biological Psychiatry. 64: 974-81. PMID 18774553 DOI: 10.1016/J.Biopsych.2008.07.018  0.231
2011 Chatterjee S, Steensland P, Simms JA, Holgate J, Coe JW, Hurst RS, Shaffer CL, Lowe J, Rollema H, Bartlett SE. Partial agonists of the α3β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 603-15. PMID 21048701 DOI: 10.1038/Npp.2010.191  0.23
2012 Simms JA, Haass-Koffler CL, Bito-Onon J, Li R, Bartlett SE. Mifepristone in the central nucleus of the amygdala reduces yohimbine stress-induced reinstatement of ethanol-seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 906-18. PMID 22048462 DOI: 10.1038/Npp.2011.268  0.228
2014 Simms JA, Nielsen CK, Li R, Bartlett SE. Intermittent access ethanol consumption dysregulates CRF function in the hypothalamus and is attenuated by the CRF-R1 antagonist, CP-376395. Addiction Biology. 19: 606-11. PMID 23362976 DOI: 10.1111/Adb.12024  0.228
2012 Nielsen CK, Simms JA, Bito-Onon JJ, Li R, Ananthan S, Bartlett SE. The delta opioid receptor antagonist, SoRI-9409, decreases yohimbine stress-induced reinstatement of ethanol-seeking. Addiction Biology. 17: 224-34. PMID 21309957 DOI: 10.1111/J.1369-1600.2010.00295.X  0.222
2008 Richards JK, Simms JA, Steensland P, Taha SA, Borgland SL, Bonci A, Bartlett SE. Inhibition of orexin-1/hypocretin-1 receptors inhibits yohimbine-induced reinstatement of ethanol and sucrose seeking in Long-Evans rats. Psychopharmacology. 199: 109-17. PMID 18470506 DOI: 10.1007/S00213-008-1136-5  0.221
2007 Steensland P, Simms JA, Holgate J, Richards JK, Bartlett SE. Varenicline, an alpha4beta2 nicotinic acetylcholine receptor partial agonist, selectively decreases ethanol consumption and seeking. Proceedings of the National Academy of Sciences of the United States of America. 104: 12518-23. PMID 17626178 DOI: 10.1073/Pnas.0705368104  0.215
2012 Srinivasan S, Simms JA, Nielsen CK, Lieske SP, Bito-Onon JJ, Yi H, Hopf FW, Bonci A, Bartlett SE. The dual orexin/hypocretin receptor antagonist, almorexant, in the ventral tegmental area attenuates ethanol self-administration. Plos One. 7: e44726. PMID 23028593 DOI: 10.1371/Journal.Pone.0044726  0.212
2009 Corl AB, Berger KH, Ophir-Shohat G, Gesch J, Simms JA, Bartlett SE, Heberlein U. Happyhour, a Ste20 family kinase, implicates EGFR signaling in ethanol-induced behaviors. Cell. 137: 949-60. PMID 19464045 DOI: 10.1016/J.Cell.2009.03.020  0.207
2012 Nielsen CK, Simms JA, Li R, Mill D, Yi H, Feduccia AA, Santos N, Bartlett SE. δ-opioid receptor function in the dorsal striatum plays a role in high levels of ethanol consumption in rats. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4540-52. PMID 22457501 DOI: 10.1523/Jneurosci.5345-11.2012  0.2
2010 Simms JA, Bito-Onon JJ, Chatterjee S, Bartlett SE. Long-Evans rats acquire operant self-administration of 20% ethanol without sucrose fading. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1453-63. PMID 20200505 DOI: 10.1038/Npp.2010.15  0.192
2010 Qi T, Simms J, Bailey RJ, Wheatley M, Rathbone DL, Hay DL, Poyner DR. Structure-function analysis of RAMP1-RAMP3 chimeras. Biochemistry. 49: 522-31. PMID 20017504 DOI: 10.1021/bi9019093  0.191
2014 Feduccia AA, Simms JA, Mill D, Yi HY, Bartlett SE. Varenicline decreases ethanol intake and increases dopamine release via neuronal nicotinic acetylcholine receptors in the nucleus accumbens. British Journal of Pharmacology. 171: 3420-31. PMID 24628360 DOI: 10.1111/Bph.12690  0.191
2011 Simms JA, Richards JK, Mill D, Kanholm I, Holgate JY, Bartlett SE. Induction of multiple reinstatements of ethanol- and sucrose-seeking behavior in Long-Evans rats by the α-2 adrenoreceptor antagonist yohimbine. Psychopharmacology. 218: 101-10. PMID 21863233 DOI: 10.1007/S00213-011-2451-9  0.191
2009 Richards JK, Simms JA, Bartlett SE. Conditioned cues and yohimbine induce reinstatement of beer and near-beer seeking in Long-Evans rats. Addiction Biology. 14: 144-51. PMID 19076928 DOI: 10.1111/J.1369-1600.2008.00139.X  0.191
2011 Bito-Onon JJ, Simms JA, Chatterjee S, Holgate J, Bartlett SE. Varenicline, a partial agonist at neuronal nicotinic acetylcholine receptors, reduces nicotine-induced increases in 20% ethanol operant self-administration in Sprague-Dawley rats. Addiction Biology. 16: 440-9. PMID 21392178 DOI: 10.1111/J.1369-1600.2010.00309.X  0.19
2008 Simms JA, Steensland P, Medina B, Abernathy KE, Chandler LJ, Wise R, Bartlett SE. Intermittent access to 20% ethanol induces high ethanol consumption in Long-Evans and Wistar rats. Alcoholism, Clinical and Experimental Research. 32: 1816-23. PMID 18671810 DOI: 10.1111/J.1530-0277.2008.00753.X  0.19
2013 Mill DJ, Bito-Onon JJ, Simms JA, Li R, Bartlett SE. Fischer rats consume 20% ethanol in a long-term intermittent-access two-bottle-choice paradigm. Plos One. 8: e79824. PMID 24244567 DOI: 10.1371/Journal.Pone.0079824  0.183
2006 Conner AC, Simms J, Howitt SG, Wheatley M, Poyner DR. The second intracellular loop of the calcitonin gene-related peptide receptor provides molecular determinants for signal transduction and cell surface expression. The Journal of Biological Chemistry. 281: 1644-51. PMID 16293613 DOI: 10.1074/jbc.M510064200  0.182
2011 Landgren S, Simms JA, Thelle DS, Strandhagen E, Bartlett SE, Engel JA, Jerlhag E. The ghrelin signalling system is involved in the consumption of sweets. Plos One. 6: e18170. PMID 21448464 DOI: 10.1371/Journal.Pone.0018170  0.18
2009 Harikumar KG, Simms J, Christopoulos G, Sexton PM, Miller LJ. Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptor. Biochemistry. 48: 11773-85. PMID 19886671 DOI: 10.1021/bi901326k  0.179
2013 Seif T, Chang SJ, Simms JA, Gibb SL, Dadgar J, Chen BT, Harvey BK, Ron D, Messing RO, Bonci A, Hopf FW. Cortical activation of accumbens hyperpolarization-active NMDARs mediates aversion-resistant alcohol intake. Nature Neuroscience. 16: 1094-100. PMID 23817545 DOI: 10.1038/Nn.3445  0.179
2003 Hawtin SR, Wesley VJ, Simms J, Parslow RA, Miles A, McEwan K, Keen M, Wheatley M. An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist. European Journal of Biochemistry / Febs. 270: 4681-8. PMID 14622255 DOI: 10.1046/j.1432-1033.2003.03865.x  0.176
2012 Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activation. The Journal of Biological Chemistry. 287: 3642-58. PMID 22147710 DOI: 10.1074/jbc.M111.309328  0.175
2012 Feduccia AA, Wang Y, Simms JA, Yi HY, Li R, Bjeldanes L, Ye C, Bartlett SE. Locomotor activation by theacrine, a purine alkaloid structurally similar to caffeine: involvement of adenosine and dopamine receptors. Pharmacology, Biochemistry, and Behavior. 102: 241-8. PMID 22579816 DOI: 10.1016/J.Pbb.2012.04.014  0.174
2007 Conner AC, Simms J, Barwell J, Wheatley M, Poyner DR. Ligand binding and activation of the CGRP receptor. Biochemical Society Transactions. 35: 729-32. PMID 17635135 DOI: 10.1042/BST0350729  0.172
2005 Conner AC, Hay DL, Simms J, Howitt SG, Schindler M, Smith DM, Wheatley M, Poyner DR. A key role for transmembrane prolines in calcitonin receptor-like receptor agonist binding and signalling: implications for family B G-protein-coupled receptors. Molecular Pharmacology. 67: 20-31. PMID 15615699 DOI: 10.1124/mol.67.1.  0.172
2012 Sexton PM, Poyner DR, Simms J, Christopoulos A, Hay DL. RAMPs as drug targets. Advances in Experimental Medicine and Biology. 744: 61-74. PMID 22434108 DOI: 10.1007/978-1-4614-2364-5_6  0.169
2011 Wootten DL, Simms J, Massoura AJ, Trim JE, Wheatley M. Agonist-specific requirement for a glutamate in transmembrane helix 1 of the oxytocin receptor. Molecular and Cellular Endocrinology. 333: 20-7. PMID 21130837 DOI: 10.1016/j.mce.2010.11.029  0.165
2012 Barwell J, Wootten D, Simms J, Hay DL, Poyner DR. RAMPs and CGRP receptors. Advances in Experimental Medicine and Biology. 744: 13-24. PMID 22434104 DOI: 10.1007/978-1-4614-2364-5_2  0.165
2010 Chugunov AO, Simms J, Poyner DR, Dehouck Y, Rooman M, Gilis D, Langer I. Evidence that interaction between conserved residues in transmembrane helices 2, 3, and 7 are crucial for human VPAC1 receptor activation. Molecular Pharmacology. 78: 394-401. PMID 20573782 DOI: 10.1124/mol.110.063578  0.165
2002 Hawtin SR, Wesley VJ, Parslow RA, Simms J, Miles A, McEwan K, Wheatley M. A single residue (arg46) located within the N-terminus of the V1a vasopressin receptor is critical for binding vasopressin but not peptide or nonpeptide antagonists. Molecular Endocrinology (Baltimore, Md.). 16: 600-9. PMID 11875119 DOI: 10.1210/mend.16.3.0795  0.165
2006 Conner AC, Simms J, Conner MT, Wootten DL, Wheatley M, Poyner DR. Diverse functional motifs within the three intracellular loops of the CGRP1 receptor. Biochemistry. 45: 12976-85. PMID 17059214 DOI: 10.1021/bi0615801  0.163
2007 Conner M, Hawtin SR, Simms J, Wootten D, Lawson Z, Conner AC, Parslow RA, Wheatley M. Systematic analysis of the entire second extracellular loop of the V(1a) vasopressin receptor: key residues, conserved throughout a G-protein-coupled receptor family, identified. The Journal of Biological Chemistry. 282: 17405-12. PMID 17403667 DOI: 10.1074/jbc.M702151200  0.161
2004 Conner AC, Simms J, Hay DL, Mahmoud K, Howitt SG, Wheatley M, Poyner DR. Heterodimers and family-B GPCRs: RAMPs, CGRP and adrenomedullin. Biochemical Society Transactions. 32: 843-6. PMID 15494030 DOI: 10.1042/BST0320843  0.16
2009 Simms J, Hay DL, Bailey RJ, Konycheva G, Bailey G, Wheatley M, Poyner DR. Structure-function analysis of RAMP1 by alanine mutagenesis. Biochemistry. 48: 198-205. PMID 19072332 DOI: 10.1021/bi801869n  0.158
2007 Wheatley M, Simms J, Hawtin SR, Wesley VJ, Wootten D, Conner M, Lawson Z, Conner AC, Baker A, Cashmore Y, Kendrick R, Parslow RA. Extracellular loops and ligand binding to a subfamily of Family A G-protein-coupled receptors. Biochemical Society Transactions. 35: 717-20. PMID 17635132 DOI: 10.1042/BST0350717  0.157
2012 Leach K, Simms J, Sexton PM, Christopoulos A. Structure-function studies of muscarinic acetylcholine receptors. Handbook of Experimental Pharmacology. 29-48. PMID 22222693 DOI: 10.1007/978-3-642-23274-9_2  0.157
2013 Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM. Polar transmembrane interactions drive formation of ligand-specific and signal pathway-biased family B G protein-coupled receptor conformations. Proceedings of the National Academy of Sciences of the United States of America. 110: 5211-6. PMID 23479653 DOI: 10.1073/pnas.1221585110  0.157
2015 Koole C, Wootten D, Simms J, Miller LJ, Christopoulos A, Sexton PM. Differential impact of amino acid substitutions on critical residues of the human glucagon-like peptide-1 receptor involved in peptide activity and small-molecule allostery. The Journal of Pharmacology and Experimental Therapeutics. 353: 52-63. PMID 25630467 DOI: 10.1124/jpet.114.220913  0.156
2011 Koole C, Wootten D, Simms J, Valant C, Miller LJ, Christopoulos A, Sexton PM. Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: allosteric rescue of loss of function mutation. Molecular Pharmacology. 80: 486-97. PMID 21616920 DOI: 10.1124/mol.111.072884  0.153
2006 Hawtin SR, Simms J, Conner M, Lawson Z, Parslow RA, Trim J, Sheppard A, Wheatley M. Charged extracellular residues, conserved throughout a G-protein-coupled receptor family, are required for ligand binding, receptor activation, and cell-surface expression. The Journal of Biological Chemistry. 281: 38478-88. PMID 16990262 DOI: 10.1074/jbc.M607639200  0.151
2004 Hay DL, Conner AC, Howitt SG, Takhshid MA, Simms J, Mahmoud K, Poyner DR. The pharmacology of CGRP-responsive receptors in cultured and transfected cells. Peptides. 25: 2019-26. PMID 15501536 DOI: 10.1016/j.peptides.2004.06.007  0.15
2012 Koole C, Wootten D, Simms J, Savage EE, Miller LJ, Christopoulos A, Sexton PM. Second extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) differentially regulates orthosteric but not allosteric agonist binding and function. The Journal of Biological Chemistry. 287: 3659-73. PMID 22147709 DOI: 10.1074/jbc.M111.309369  0.15
2005 Hawtin SR, Wesley VJ, Simms J, Argent CC, Latif K, Wheatley M. The N-terminal juxtamembrane segment of the V1a vasopressin receptor provides two independent epitopes required for high-affinity agonist binding and signaling. Molecular Endocrinology (Baltimore, Md.). 19: 2871-81. PMID 15994199 DOI: 10.1210/me.2005-0148  0.15
2012 Landgren S, Simms JA, Hyytiä P, Engel JA, Bartlett SE, Jerlhag E. Ghrelin receptor (GHS-R1A) antagonism suppresses both operant alcohol self-administration and high alcohol consumption in rats. Addiction Biology. 17: 86-94. PMID 21309944 DOI: 10.1111/J.1369-1600.2010.00280.X  0.15
2006 Simms J, Hay DL, Wheatley M, Poyner DR. Characterization of the structure of RAMP1 by mutagenesis and molecular modeling. Biophysical Journal. 91: 662-9. PMID 16632510 DOI: 10.1529/biophysj.106.084582  0.149
2003 Wheatley M, Hawtin SR, Wesley VJ, Howard HC, Simms J, Miles A, McEwan K, Parslow RA. Agonist binding to peptide hormone receptors. Biochemical Society Transactions. 31: 35-9. PMID 12546649 DOI: 10.1042/  0.146
2011 Hopf FW, Simms JA, Chang SJ, Seif T, Bartlett SE, Bonci A. Chlorzoxazone, an SK-type potassium channel activator used in humans, reduces excessive alcohol intake in rats. Biological Psychiatry. 69: 618-24. PMID 21195386 DOI: 10.1016/J.Biopsych.2010.11.011  0.146
2009 Sexton PM, Poyner DR, Simms J, Christopoulos A, Hay DL. Modulating receptor function through RAMPs: can they represent drug targets in themselves? Drug Discovery Today. 14: 413-9. PMID 19150656 DOI: 10.1016/j.drudis.2008.12.009  0.145
2010 Wootten DL, Simms J, Hay DL, Christopoulos A, Sexton PM. Receptor activity modifying proteins and their potential as drug targets. Progress in Molecular Biology and Translational Science. 91: 53-79. PMID 20691959 DOI: 10.1016/S1877-1173(10)91003-X  0.137
2015 Booe JM, Walker CS, Barwell J, Kuteyi G, Simms J, Jamaluddin MA, Warner ML, Bill RM, Harris PW, Brimble MA, Poyner DR, Hay DL, Pioszak AA. Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Molecular Cell. 58: 1040-52. PMID 25982113 DOI: 10.1016/J.Molcel.2015.04.018  0.137
2012 Wheatley M, Wootten D, Conner MT, Simms J, Kendrick R, Logan RT, Poyner DR, Barwell J. Lifting the lid on GPCRs: the role of extracellular loops. British Journal of Pharmacology. 165: 1688-703. PMID 21864311 DOI: 10.1111/j.1476-5381.2011.01629.x  0.136
2019 Li KX, He M, Ye W, Simms J, Gill M, Xiang X, Jan YN, Jan LY. TMEM16B regulates anxiety-related behavior and GABAergic neuronal signaling in the central lateral amygdala. Elife. 8. PMID 31482844 DOI: 10.7554/Elife.47106  0.134
2010 Just R, Simms J, Furness SGB, Christopoulos A, Sexton PM. Understanding amylin Receptors The Calcitonin Gene-Related Peptide Family: Form, Function and Future Perspectives. 41-57. DOI: 10.1007/978-90-481-2909-6_3  0.133
2010 Koole C, Wootten D, Simms J, Valant C, Sridhar R, Woodman OL, Miller LJ, Summers RJ, Christopoulos A, Sexton PM. Allosteric ligands of the glucagon-like peptide 1 receptor (GLP-1R) differentially modulate endogenous and exogenous peptide responses in a pathway-selective manner: implications for drug screening. Molecular Pharmacology. 78: 456-65. PMID 20547734 DOI: 10.1124/mol.110.065664  0.128
2015 Seif T, Simms JA, Lei K, Wegner S, Bonci A, Messing RO, Hopf FW. D-Serine and D-Cycloserine Reduce Compulsive Alcohol Intake in Rats. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 25801502 DOI: 10.1038/Npp.2015.84  0.128
2011 Wootten D, Simms J, Koole C, Woodman OL, Summers RJ, Christopoulos A, Sexton PM. Modulation of the glucagon-like peptide-1 receptor signaling by naturally occurring and synthetic flavonoids. The Journal of Pharmacology and Experimental Therapeutics. 336: 540-50. PMID 21075839 DOI: 10.1124/jpet.110.176362  0.127
2016 Lei K, Wegner SA, Yu JH, Simms JA, Hopf FW. A single alcohol drinking session is sufficient to enable subsequent aversion-resistant consumption in mice. Alcohol (Fayetteville, N.Y.). 55: 9-16. PMID 27788780 DOI: 10.1016/j.alcohol.2016.07.008  0.126
2017 Lei K, Seif T, Simms JA, Wegner S, Hu B, Bonci A, Messing RO, Woodward Hopf F. How do we drink despite consequences: Exploring the hypothesis that the Insula instigates AUDs Alcohol. 60: 211. DOI: 10.1016/J.Alcohol.2017.02.218  0.124
2010 Gregory KJ, Valant C, Simms J, Sexton PM, Christopoulos A. The Emergence of Allosteric Modulators for G Protein-Coupled Receptors Gpcr Molecular Pharmacology and Drug Targeting: Shifting Paradigms and New Directions. 61-87. DOI: 10.1002/9780470627327.ch3  0.122
2006 Perreault ML, Graham D, Bisnaire L, Simms J, Hayton S, Szechtman H. Kappa-opioid agonist U69593 potentiates locomotor sensitization to the D2/D3 agonist quinpirole: pre- and postsynaptic mechanisms. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 1967-81. PMID 16237381 DOI: 10.1038/Sj.Npp.1300938  0.121
2010 Simms J. Homology Modelling of G Protein-Coupled Receptors G Protein-Coupled Receptors: Essential Methods. 251-273. DOI: 10.1002/9780470749210.ch13  0.12
2023 Saha P, Andersen RE, Hong SJ, Gil E, Simms J, Lim DA. Sex-specific role for the long noncoding RNA in mouse behavior. Biorxiv : the Preprint Server For Biology. PMID 38105981 DOI: 10.1101/2023.12.05.569777  0.115
2020 Hanson JE, Ma K, Elstrott J, Weber M, Saillet S, Khan AS, Simms J, Liu B, Kim TA, Yu GQ, Chen Y, Wang TM, Jiang Z, Liederer BM, Deshmukh G, et al. GluN2A NMDA Receptor Enhancement Improves Brain Oscillations, Synchrony, and Cognitive Functions in Dravet Syndrome and Alzheimer's Disease Models. Cell Reports. 30: 381-396.e4. PMID 31940483 DOI: 10.1016/J.Celrep.2019.12.030  0.115
2017 Orr AG, Lo I, Schumacher H, Ho K, Gill M, Guo W, Kim DH, Knox A, Saito T, Saido TC, Simms J, Toddes C, Wang X, Yu GQ, Mucke L. Istradefylline reduces memory deficits in aging mice with amyloid pathology. Neurobiology of Disease. PMID 29100987 DOI: 10.1016/J.Nbd.2017.10.014  0.111
2009 Simms J, Hall NE, Lam PH, Miller LJ, Christopoulos A, Abagyan R, Sexton PM. Homology modeling of GPCRs. Methods in Molecular Biology (Clifton, N.J.). 552: 97-113. PMID 19513644 DOI: 10.1007/978-1-60327-317-6_7  0.109
2012 Koole C, Wootten D, Simms J, Valant C, Miller LJ, Christopoulos A, Sexton PM. Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: Allosteric rescue of loss of function mutation (Molecular Pharmacology (2011) 80, (486-497)) Molecular Pharmacology. 82: 142. DOI: 10.1124/mol.82.1.142  0.109
2021 Arguello A, Meisner R, Thomsen ER, Nguyen HN, Ravi R, Simms J, Lo I, Speckart J, Holtzman J, Gill TM, Chan D, Cheng Y, Chiu CL, Dugas JC, Fang M, et al. Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome. Jci Insight. 6. PMID 34622797 DOI: 10.1172/jci.insight.145445  0.107
2019 Wang L, Simms J, Peters CJ, Fontaine MT, Li K, Gill TM, Nung Jan Y, Jan LY. TMEM16B calcium-activated chloride channels regulate action potential firing in lateral septum and aggression in male mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31320449 DOI: 10.1523/Jneurosci.3137-18.2019  0.106
2017 Haass-Koffler CL, Henry AT, Melkus G, Simms JA, Naemmuddin M, Nielsen CK, Lasek AW, Magill M, Schwandt ML, Momenan R, Hodgkinson CA, Bartlett SE, Swift RM, Bonci A, Leggio L. A chimeric approach to evaluate the role of corticotropin releasing factor in alcohol use disorder Alcohol. 60: 222-223. DOI: 10.1016/J.Alcohol.2017.02.267  0.097
2020 Díaz-Alonso J, Morishita W, Incontro S, Simms J, Holtzman J, Gill M, Mucke L, Malenka RC, Nicoll RA. Long-term potentiation is independent of the C-tail of the GluA1 AMPA receptor subunit. Elife. 9. PMID 32831170 DOI: 10.7554/Elife.58042  0.092
2022 Shao E, Chang CW, Li Z, Yu X, Ho K, Zhang M, Wang X, Simms J, Lo I, Speckart J, Holtzman J, Yu GQ, Roberson ED, Mucke L. TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model. Science Translational Medicine. 14: eabm5527. PMID 35476595 DOI: 10.1126/scitranslmed.abm5527  0.088
2008 Reynolds PJ, Simms JR, Duronio RJ. Identifying determinants of cullin binding specificity among the three functionally different Drosophila melanogaster Roc proteins via domain swapping. Plos One. 3: e2918. PMID 18698375 DOI: 10.1371/Journal.Pone.0002918  0.084
2010 Kusenbach M, Simms JL, Tobin GA. Disaster vulnerability and evacuation readiness: Coastal mobile home residents in Florida Natural Hazards. 52: 79-95. DOI: 10.1007/S11069-009-9358-3  0.069
2014 Harris NJ, Findlay HE, Simms J, Liu X, Booth PJ. Relative domain folding and stability of a membrane transport protein. Journal of Molecular Biology. 426: 1812-25. PMID 24530957 DOI: 10.1016/j.jmb.2014.01.012  0.067
2022 Lin King YH, Chen C, Lin King JV, Simms J, Glasscock E, Yang SB, Jan YN, Jan LY. K1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118240119. PMID 35613055 DOI: 10.1073/pnas.2118240119  0.065
2015 Colten CE, Grimsmore AA, Simms JRZ. Oil Spills and Community Resilience: Uneven Impacts and Protection in Historical Perspective Geographical Review. 105: 391-407. DOI: 10.1111/J.1931-0846.2015.12085.X  0.063
1994 Chegini N, Simms J, Williams RS, Masterson BJ. Identification of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in surgically induced pelvic adhesions in the rat and intraperitoneal adhesions in the human. American Journal of Obstetrics and Gynecology. 171: 321-7; discussion 32. PMID 8059808  0.061
2010 Lankshear A, Harden J, Simms J. Safe practice for patients receiving anticoagulant therapy. Nursing Standard (Royal College of Nursing (Great Britain) : 1987). 24: 47-54; quiz 56. PMID 20191745 DOI: 10.7748/ns2010.01.24.20.47.c8157  0.06
1991 Simms JS, Chegini N, Williams RS, Rossi AM, Dunn WA. Identification of epidermal growth factor, transforming growth factor-alpha, and epidermal growth factor receptor in surgically induced endometriosis in rats. Obstetrics and Gynecology. 78: 850-7. PMID 1923211  0.058
2014 Yelvington KA, Dillon-Sumner LD, Simms JL. Pleasure policies: Debating development plans in southern California's Wine Country Journal of Policy Research in Tourism, Leisure and Events. 6: 95-118. DOI: 10.1080/19407963.2014.926127  0.058
2015 Williams MT, Sawyer B, Leonard RC, Ellsworth M, Simms J, Riemann BC. Minority participation in a major residential and intensive outpatient program for obsessive-compulsive disorder Journal of Obsessive-Compulsive and Related Disorders. 5: 67-75. DOI: 10.1016/J.Jocrd.2015.02.004  0.058
1984 Stoddard CJ, Simms JM. Dilatation of benign oesophageal strictures in the outpatient department. The British Journal of Surgery. 71: 752-3. PMID 6487972  0.055
1983 Simms JR. Quantification of behavior. Behavioral Science. 28: 274-83. PMID 6639569  0.055
2014 Landgren S, Simms JA, Thelle DS, Strandhagen E, Bartlett SE, Engel JA, Jerlhag E. Correction: The ghrelin signalling system is involved in the consumption of sweets (PLoS ONE) Plos One. 9. DOI: 10.1371/Annotation/69C18638-12De-4F08-9A3C-F8C7Bf3A0Cc6  0.053
2012 Rooker JR, Simms JR, Wells RJ, Holt SA, Holt GJ, Graves JE, Furey NB. Distribution and habitat associations of billfish and swordfish larvae across mesoscale features in the Gulf of Mexico. Plos One. 7: e34180. PMID 22509277 DOI: 10.1371/Journal.Pone.0034180  0.053
2022 Robbins J, Graham BZ, Garman AN, Smith Hall R, Simms J. Closing the Gender Gap in Healthcare Leadership: Can Administrative Fellowships Play a Role? Journal of Healthcare Management / American College of Healthcare Executives. 67: 436-445. PMID 36350581 DOI: 10.1097/JHM-D-21-00314  0.053
2013 Heath O, English D, Simms J, Ward P, Hollett A, Dominic A. Improving collaborative care in managing eating disorders: a pilot study. The Journal of Continuing Education in the Health Professions. 33: 235-43. PMID 24347102 DOI: 10.1002/chp.21187  0.05
2016 Morrissey TW, Oellerich D, Meade E, Simms J, Stock A. Neighborhood poverty and children's food insecurity Children and Youth Services Review. 66: 85-93. DOI: 10.1016/j.childyouth.2016.05.006  0.05
2013 Simms J, Booth PJ. Membrane proteins by accident or design. Current Opinion in Chemical Biology. 17: 976-81. PMID 24466578 DOI: 10.1016/j.cbpa.2013.10.005  0.047
2009 Phillips CL, Geddes ND, Simms JT. A visualization approach for group behaviors, beliefs and intentions to support critical decisions Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 5621: 91-100. DOI: 10.1007/978-3-642-02774-1_10  0.046
2011 Vivekananda U, Manjalay ZR, Ganesalingam J, Simms J, Shaw CE, Leigh PN, Turner MR, Al-Chalabi A. Low index-to-ring finger length ratio in sporadic ALS supports prenatally defined motor neuronal vulnerability. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 635-7. PMID 21551173 DOI: 10.1136/Jnnp.2010.237412  0.045
1991 Simms JR. Measurement of the information associated with muscle behavior. Behavioral Science. 36: 140-7. PMID 2049056  0.045
2013 Simms JL, Kusenbach M, Tobin GA. Equally unprepared: Assessing the hurricane vulnerability of undergraduate students Weather, Climate, and Society. 5: 233-243. DOI: 10.1175/Wcas-D-12-00056.1  0.044
2014 Johansen KM, Castro NS, Lancaster KE, Madrid E, Havas A, Simms J, Sterling CR. Characterization of Giardia lamblia genotypes in dogs from Tucson, Arizona using SSU-rRNA and β-giardin sequences. Parasitology Research. 113: 387-90. PMID 24233408 DOI: 10.1007/S00436-013-3666-Y  0.043
2010 Simms J, Lund L, Hallberg K, Lowder R, Beck B. A base-wide vapor intrusion evaluation at Marine Corps Base Camp Lejeune: Utilizing the DoD phased approach to prioritize building investigations Air and Waste Management Association - Vapor Intrusion 2010. 2: 1020-1052.  0.043
2012 Toquero L, Gadd R, Owers CE, Simms JM. Post-coital haemoperitoneum: a downside to intercourse. Annals of the Royal College of Surgeons of England. 94: e26-7. PMID 22524918 DOI: 10.1308/003588412X13171221499586  0.04
1984 Reid DA, Bird NC, Simms JM, Stoddard CJ, Eyre-Brook I, Johnson AG. Controlled trial of the Grassi (pH) intraoperative test for completion of proximal gastric vagotomy. Surgery, Gynecology & Obstetrics. 158: 370-4. PMID 6369584  0.039
1977 Pitts JD, Simms JW. Permeability of junctions between animal cells. Intercellular transfer of nucleotides but not of macromolecules. Experimental Cell Research. 104: 153-63. PMID 836400 DOI: 10.1016/0014-4827(77)90078-7  0.039
2014 Cornett L, Simms J. At the 'heart' of the matter: an exploration of the psychological impact of living with congenital heart disease in adulthood. Journal of Health Psychology. 19: 393-406. PMID 23407131 DOI: 10.1177/1359105312471569  0.038
2000 Simms JR, Heath AW, Jennings R. Use of herpes simplex virus (HSV) type 1 ISCOMS 703 vaccine for prophylactic and therapeutic treatment of primary and recurrent HSV-2 infection in guinea pigs. The Journal of Infectious Diseases. 181: 1240-8. PMID 10762560 DOI: 10.1086/315376  0.037
2001 Hallam NB, West JR, Forster CF, Simms J. The potential for biofilm growth in water distribution systems. Water Research. 35: 4063-71. PMID 11791835 DOI: 10.1016/S0043-1354(01)00248-2  0.037
1992 Simms JR, Woods DA, Walley DR, Keough T, Schwab BS, Larson RJ. Integrated approach to surfactant environmental safety assessment: fast atom bombardment mass spectrometry and liquid scintillation counting to determine the mechanism and kinetics of surfactant biodegradation. Analytical Chemistry. 64: 2951-7. PMID 1463217  0.037
1983 Cooper JC, Nicholls AJ, Simms JM, Platts MM, Brown CB, Johnson AG. Genital oedema in patients treated by continuous ambulatory peritoneal dialysis: an unusual presentation of inguinal hernia. British Medical Journal (Clinical Research Ed.). 286: 1923-4. PMID 6407636  0.037
1996 Feher MD, Simms JP, Lant AF. History of chicken pox and steroid cards: a new warning? Bmj (Clinical Research Ed.). 312: 542-3. PMID 8595283  0.036
1978 Stoddard CJ, Kay PH, Simms JM, Kennedy A, Hughes P. Acute abdominal complications of systemic lupus erythematosus. The British Journal of Surgery. 65: 625-8. PMID 698534  0.036
1997 Simms JR, Heath AW, Richardson VJ, Jennings R. Large scale comparison of adjuvant effects on immunogenicity and protection in a herpes simplex virus type 1 vaccination model. Biochemical Society Transactions. 25: 272S. PMID 9191316  0.036
1983 McCormack T, Simms JM, Johnson AG, Thornton JA. Oesophageal varices: evaluation of injection sclerotherapy without general anaesthesia using the flexible fibreoptic gastroscope. Annals of the Royal College of Surgeons of England. 65: 207. PMID 6859787  0.035
2002 Simms JR, Jennings R, Richardson VJ, Heath AW. Large-scale comparison of experimental adjuvants with herpes simplex virus vaccine reveals a correlation of protection with IgG2a and IgG2b responses. Journal of Medical Virology. 68: 82-91. PMID 12210434 DOI: 10.1002/jmv.10173  0.034
1970 Simms JG, Rosser WW. Farmer's Lung in Urbanites. Canadian Family Physician MéDecin De Famille Canadien. 16: 69-71. PMID 20468586  0.034
2015 Simms JM, An X, Brittelle MS, Ramesh V, Ghandhi JB, Sanders ST. Simultaneous optimization method for absorption spectroscopy postprocessing. Applied Optics. 54: 4403-10. PMID 25967495 DOI: 10.1364/Ao.54.004403  0.033
2010 Knowlton DS, Simms J. Computer-based instruction and generative strategies: Conceptual framework & illustrative example Computers in Human Behavior. 26: 996-1003. DOI: 10.1016/j.chb.2010.02.013  0.033
1998 Jennings R, Simms JR, Heath AW. Adjuvants and delivery systems for viral vaccines--mechanisms and potential. Developments in Biological Standardization. 92: 19-28. PMID 9554256  0.033
2013 Law I, Simms J, Sirriyeh A. Challenging racist violence and racist hostility in 'post-racial' times: Research and action in leeds, UK, 2006–2012 Social Inclusion. 1: 13-20. DOI: 10.12924/si2013.01010013  0.033
1998 Simms JR, Heath AW, Richardson VJ, Jennings R. Humoral response to HSV-1 subunit vaccines--a statistical analysis. Developments in Biological Standardization. 92: 335-40. PMID 9554289  0.031
2007 Simms J, McCormack V, Anderson R, Mulholland C. Correlates of self-harm behaviour in acutely ill patients with schizophrenia. Psychology and Psychotherapy. 80: 39-49. PMID 17346379 DOI: 10.1348/147608306X99386  0.03
2013 Simms J, Pavavicharn S. Generator stator protection 2013 66th Annual Conference For Protective Relay Engineers, Cpre 2013. 505-528. DOI: 10.1109/CPRE.2013.6822059  0.03
2013 Simms J, Johnson G. Protective relaying methods for reducing arc flash energy Ieee Transactions On Industry Applications. 49: 803-813. DOI: 10.1109/TIA.2013.2240645  0.03
1981 Rosser WW, Simms JG, Patten DW, Forster J. Improving benzodiazepine prescribing in family practice through review and education. Canadian Medical Association Journal. 124: 147-53. PMID 6109564  0.029
2011 Simms JR. Making the soft sciences hard: The Newton model Systems Research and Behavioral Science. 28: 40-50. DOI: 10.1002/sres.1033  0.029
2011 Simms J, Callan S. Finding a theoretical position: Using ‘literature’ to support investigation and practice Work-Based Research in the Early Years. 62-76. DOI: 10.4135/9781446250778.n5  0.027
2012 Butler DK, Simms JE, Furey JS, Bennett HH. Review of magnetic modeling for UXO and applications to small items and close distances Journal of Environmental and Engineering Geophysics. 17: 53-73. DOI: 10.2113/JEEG17.2.53  0.027
1964 SGUROS PL, SIMMS J. ROLE OF MARINE FUNGI IN THE BIOCHEMISTRY OF THE OCEANS. IV. GROWTH RESPONSES TO SEAWATER INORGANIC MACROCONSTITUENTS. Journal of Bacteriology. 88: 346-55. PMID 14203350  0.026
2015 Hutchenson KD, Conner RB, Johnson LB, Bennett HH, Simms JE, Yule DE. Evaluation and current results of the seismic acoustic impact monitoring assessment (SAIMA) system Journal of Environmental and Engineering Geophysics. 20: 89-100. DOI: 10.2113/JEEG20.1.89  0.023
2010 Simms JT. Ingenuity, peanut butter, and a little green leaf. World Policy Journal. 27: 75-7. PMID 20976970 DOI: 10.1162/wopj.2010.27.3.75  0.023
2015 Simms J. Features of Posttraumatic Growth Among Victims of the Northern Irish “Troubles”: Is It Possible? A Case Study Analysis Journal of Humanistic Psychology. 55: 127-152. DOI: 10.1177/0022167814533993  0.022
2010 Simms J, El-Sakka K, Valenti D, Tyrrell M, Schulte KM. Small bowel obstruction due to herniation into an extra-anatomical arterial bypass tunnel: a first case report. Annals of the Royal College of Surgeons of England. 92: W20-2. PMID 20353629 DOI: 10.1308/147870810X476728  0.021
2015 Simms JR. Principles of Quantitative Group and Society Sciences Systems Research and Behavioral Science. 32: 137-145. DOI: 10.1002/sres.2217  0.021
1992 Strife RJ, Simms JR. Quantitative analysis of crude plasma extracts by ion trap tandem mass spectrometry. Journal of the American Society For Mass Spectrometry. 3: 372-7. PMID 24243048 DOI: 10.1016/1044-0305(92)87065-7  0.021
2015 Simms J, Johnson G. Protection considerations for installation of distributed energy resources 2015 68th Annual Conference For Protective Relay Engineers, Cpre 2015. 289-301. DOI: 10.1109/CPRE.2015.7102172  0.02
1985 Simms J. The Overton experiment. Nursing Times. 81: 32-4. PMID 3848894  0.02
2011 Simms JG. The War of the Two Kings, 1685-91 A New History of Ireland: Early Modern Ireland 1534-1691. DOI: 10.1093/acprof:oso/9780199562527.003.0019  0.019
1982 Simms JM, Smith JA, Woods HF. A modified prognostic index based upon nutritional measurements. Clinical Nutrition (Edinburgh, Scotland). 1: 71-9. PMID 16829369  0.018
2013 Simms J, Yaramanci U. Foreword to the special issue on geotechnical assessment and geo-environmental engineering geophysics Journal of Environmental and Engineering Geophysics. 18: 199. DOI: 10.2113/JEEG18.4.199  0.017
1985 McCormack TT, Kennedy HJ, Salisbury J, Simms JM, Triger DR, Johnson AG. Implications of a sclerotherapy program for the medical and surgical care of bleeding in portal hypertension. Surgery, Gynecology & Obstetrics. 161: 557-62. PMID 3877998  0.017
1970 Majewski RF, Berdahl JM, Jost LD, Martin TA, Simms JC, Schmidt JG, Corrigan JR. Autoxidation of dimethisterone. Steroids. 16: 15-27. PMID 5471532 DOI: 10.1016/S0039-128X(70)80092-7  0.017
1993 Kramer F, Sasse SA, Simms JC, Leedom JM. Primary cutaneous tuberculosis after a needlestick injury from a patient with AIDS and undiagnosed tuberculosis. Annals of Internal Medicine. 119: 594-5. PMID 8363170  0.017
1988 Strife RJ, Simms JR. Mass spectrometry/mass spectrometry of prostaglandins: daughter ion spectra of derivatized and isotope-labeled E and D prostanoids. Analytical Chemistry. 60: 1800-7. PMID 3232815  0.016
1991 Zeiderman MR, Wyman A, Euinton HA, Simms JM, Rogers K. Diagnostic difficulties in patients with a pancreatic mass. Bmj (Clinical Research Ed.). 302: 1395-6. PMID 2059723  0.016
1956 SIMMS JR. Cancer: questions frequently asked by the patient. The Mississippi Doctor. 33: 313-6. PMID 13309151  0.014
2010 Simms JR, Rooker JR, Holt SA, Holt GJ, Bangma J. Distribution, growth, and mortality of sailfish (istiophorus platypterus) larvae in the northern gulf of Mexico Fishery Bulletin. 108: 478-490.  0.013
2012 Simms JR, Johnson PJ. Knowledge: A measurable universal phenomenon of life Systems Research and Behavioral Science. 29: 448-456. DOI: 10.1002/sres.2114  0.013
2003 Goodfellow PB, Fretwell IA, Simms JM. Nurse endoscopy in a district general hospital. Annals of the Royal College of Surgeons of England. 85: 181-4. PMID 12831491 DOI: 10.1308/003588403321661343  0.013
2011 Simms JE, Lobred AR. Application of magnetic susceptibility for wetlands delineation Journal of Environmental and Engineering Geophysics. 16: 105-114. DOI: 10.2113/JEEG16.3.105  0.013
1983 Ward JD, Boulton AJ, Simms JM, Sandler DA, Knight G. Venous distension in the diabetic neuropathic foot (physical sign of arteriovenous shunting). Journal of the Royal Society of Medicine. 76: 1011-4. PMID 6672192  0.013
2012 Yelvington KA, Simms JL, Murray E. Wine tourism in the Temecula valley neoliberal development policies and their contradictions Anthropology in Action. 19: 49-65. DOI: 10.3167/Aia.2012.190305  0.012
1990 Simms J, Carpenter D. Education. Mastering the art. Nursing Times. 86: 40-1. PMID 2082293  0.012
2009 Van De Mark TF, Johnson LB, Bennett J, Simms JE, Yule DE. Evaluation of seismic-acoustic analysis methods for a realtime UXO monitoring system Proceedings of the Symposium On the Application of Geophyics to Engineering and Environmental Problems, Sageep. 2: 794-803.  0.012
1978 Mehta S, Burton P, Simms JS. Monitoring of occupational exposure to nitrous oxide. Canadian Anaesthetists' Society Journal. 25: 419-23. PMID 698872  0.011
2010 Van De Mark TF, Conner R, Johnson LB, Bennet J, Simms JE, Yule DE. Technical overview of the seismic acoustic impact monitoring assessment (saima) system Proceedings of the Symposium On the Application of Geophyics to Engineering and Environmental Problems, Sageep. 2: 1065-1076.  0.011
1995 Simms J. Latex allergy alert. The Canadian Nurse. 91: 27-30. PMID 7780922  0.011
1983 Simms JM, Talbot CH. Surgery for thyrotoxicosis. The British Journal of Surgery. 70: 581-3. PMID 6688751  0.01
1983 Johnson AG, Simms JM. Parastomal haemorrhage from an ileal conduit secondary to portal hypertension. The British Journal of Surgery. 70: 187. PMID 6600953  0.01
2015 Harper-Jaques S, Simms J. Single session walk-in therapy. The Canadian Nurse. 111: 12-3. PMID 26387233  0.01
2014 Simms J. Supply and demand Drapers. 30-33.  0.01
2013 Simms J, Yaramanci U. Foreword from editors Near Surface Geophysics. 11: 587. DOI: 10.3997/1873-0604.2013048  0.01
2011 Simms JG. The Restoration, 1660-85 A New History of Ireland: Early Modern Ireland 1534-1691. DOI: 10.1093/acprof:oso/9780199562527.003.0017  0.01
2010 Simms J. Colorado minerals processing divisnom haosts 60th annual meeting Mining Engineering. 62: 37-38.  0.01
1998 Simms J, Wild C. Nursing week 1998 Aarn News Letter. 54: 15. PMID 10594994  0.01
1993 Simms J, Duff P. Viral hepatitis in pregnancy. Seminars in Perinatology. 17: 384-93. PMID 8160022  0.01
1989 Simms JC. Fixed and mobile facilities in dairy practice. The Veterinary Clinics of North America. Food Animal Practice. 5: 591-601. PMID 2819549  0.01
1985 Simms JM, Bird NC, Johnson AG. An unusual acid antrum. The British Journal of Surgery. 72: 12. PMID 3967120  0.01
1984 McCormack TT, Bailey HR, Simms JM, Johnson AG. Rectal varices are not piles. The British Journal of Surgery. 71: 163. PMID 6692118  0.01
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