| Year |
Citation |
Score |
| 2024 |
Barnett D, Zimmer TS, Booraem C, Palaguachi F, Meadows SM, Xiao H, Chouchani ET, Orr AG, Orr AL. Mitochondrial complex III-derived ROS amplify immunometabolic changes in astrocytes and promote dementia pathology. Biorxiv : the Preprint Server For Biology. PMID 39229090 DOI: 10.1101/2024.08.19.608708 |
0.573 |
|
| 2024 |
Meadows SM, Palaguachi F, Jang MW, Licht-Murava A, Barnett D, Zimmer TS, Zhou C, McDonough SR, Orr AL, Orr AG. Hippocampal astrocytes induce sex-dimorphic effects on memory. Cell Reports. 43: 114278. PMID 38795347 DOI: 10.1016/j.celrep.2024.114278 |
0.763 |
|
| 2024 |
Zimmer TS, Orr AL, Orr AG. Astrocytes in selective vulnerability to neurodegenerative disease. Trends in Neurosciences. PMID 38521710 DOI: 10.1016/j.tins.2024.02.008 |
0.36 |
|
| 2023 |
Barnett D, Bohmbach K, Grelot V, Charlet A, Dallérac G, Ju YH, Nagai J, Orr AG. Astrocytes as Drivers and Disruptors of Behavior: New Advances in Basic Mechanisms and Therapeutic Targeting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 43: 7463-7471. PMID 37940585 DOI: 10.1523/JNEUROSCI.1376-23.2023 |
0.575 |
|
| 2023 |
Garcia CP, Licht-Murava A, Orr AG. Effects of adenosine A receptors on cognitive function in health and disease. International Review of Neurobiology. 170: 121-154. PMID 37741689 DOI: 10.1016/bs.irn.2023.04.006 |
0.475 |
|
| 2023 |
Licht-Murava A, Meadows SM, Palaguachi F, Song SC, Jackvony S, Bram Y, Zhou C, Schwartz RE, Froemke RC, Orr AL, Orr AG. Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines. Science Advances. 9: eade1282. PMID 37075107 DOI: 10.1126/sciadv.ade1282 |
0.454 |
|
| 2022 |
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, Lin CC, Davis S, Ha C, Leung AW, Nguyen H, ... ... Orr AG, et al. Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia. Molecular Neurodegeneration. 17: 41. PMID 35690868 DOI: 10.1186/s13024-022-00547-7 |
0.726 |
|
| 2021 |
Murava AL, Meadows S, Palaguachi F, Song SC, Bram Y, Zhou C, Schwartz RE, Froemke RC, Orr AL, Orr AG. Dementia-linked TDP-43 dysregulation in astrocytes impairs memory, antiviral signaling, and chemokine-mediated astrocytic-neuronal interactions. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058562. PMID 34971156 DOI: 10.1002/alz.058562 |
0.382 |
|
| 2019 |
Acosta-Ruiz A, Gutzeit VA, Skelly MJ, Meadows S, Lee J, Parekh P, Orr AG, Liston C, Pleil KE, Broichhagen J, Levitz J. Branched Photoswitchable Tethered Ligands Enable Ultra-efficient Optical Control and Detection of G Protein-Coupled Receptors In Vivo. Neuron. PMID 31784287 DOI: 10.1016/J.Neuron.2019.10.036 |
0.577 |
|
| 2019 |
Mucke L, Akassoglou K, Das M, Gan L, Ho K, Merlini M, Orr A, Rafalski VA, Ryu JK, Sayed F, Seeley WW, Yu G. ASTROGLIAL AND MICROGLIAL MODULATION OF NEURAL FUNCTIONS IN MODELS OF ALZHEIMER’S DISEASE Alzheimer's & Dementia. 15: P188. DOI: 10.1016/J.Jalz.2019.06.4393 |
0.648 |
|
| 2017 |
Orr AG, Lo I, Schumacher H, Ho K, Gill M, Guo W, Kim DH, Knox A, Saito T, Saido TC, Simms J, Toddes C, Wang X, Yu GQ, Mucke L. Istradefylline reduces memory deficits in aging mice with amyloid pathology. Neurobiology of Disease. PMID 29100987 DOI: 10.1016/J.Nbd.2017.10.014 |
0.682 |
|
| 2015 |
Orr AG, Hsiao EC, Wang MM, Ho K, Kim DH, Wang X, Guo W, Kang J, Yu GQ, Adame A, Devidze N, Dubal DB, Masliah E, Conklin BR, Mucke L. Astrocytic adenosine receptor A2A and Gs-coupled signaling regulate memory. Nature Neuroscience. 18: 423-34. PMID 25622143 DOI: 10.1038/Nn.3930 |
0.764 |
|
| 2012 |
Sanchez PE, Zhu L, Verret L, Vossel KA, Orr AG, Cirrito JR, Devidze N, Ho K, Yu GQ, Palop JJ, Mucke L. Levetiracetam suppresses neuronal network dysfunction and reverses synaptic and cognitive deficits in an Alzheimer's disease model. Proceedings of the National Academy of Sciences of the United States of America. 109: E2895-903. PMID 22869752 DOI: 10.1073/Pnas.1121081109 |
0.746 |
|
| 2011 |
Cissé M, Halabisky B, Harris J, Devidze N, Dubal DB, Sun B, Orr A, Lotz G, Kim DH, Hamto P, Ho K, Yu GQ, Mucke L. Reversing EphB2 depletion rescues cognitive functions in Alzheimer model. Nature. 469: 47-52. PMID 21113149 DOI: 10.1038/Nature09635 |
0.79 |
|
| 2010 |
Mullasseril P, Hansen KB, Vance KM, Ogden KK, Yuan H, Kurtkaya NL, Santangelo R, Orr AG, Le P, Vellano KM, Liotta DC, Traynelis SF. A subunit-selective potentiator of NR2C- and NR2D-containing NMDA receptors. Nature Communications. 1: 90. PMID 20981015 DOI: 10.1038/Ncomms1085 |
0.741 |
|
| 2010 |
Hansen KB, Mullasseril P, Dawit S, Kurtkaya NL, Yuan H, Vance KM, Orr AG, Kvist T, Ogden KK, Le P, Vellano KM, Lewis I, Kurtkaya S, Du Y, Qui M, et al. Implementation of a fluorescence-based screening assay identifies histamine H3 receptor antagonists clobenpropit and iodophenpropit as subunit-selective N-methyl-D-aspartate receptor antagonists. The Journal of Pharmacology and Experimental Therapeutics. 333: 650-62. PMID 20197375 DOI: 10.1124/Jpet.110.166256 |
0.742 |
|
| 2010 |
Orr AG, Sharma A, Binder NB, Miller AH, Pearce BD. Interleukin-1 mediates long-term hippocampal dentate granule cell loss following postnatal viral infection. Journal of Molecular Neuroscience : Mn. 41: 89-96. PMID 19774496 DOI: 10.1007/S12031-009-9293-5 |
0.343 |
|
| 2009 |
Gyoneva S, Orr AG, Traynelis SF. Differential regulation of microglial motility by ATP/ADP and adenosine. Parkinsonism & Related Disorders. 15: S195-9. PMID 20082989 DOI: 10.1016/S1353-8020(09)70813-2 |
0.761 |
|
| 2009 |
Orr AG, Orr AL, Li XJ, Gross RE, Traynelis SF. Adenosine A(2A) receptor mediates microglial process retraction. Nature Neuroscience. 12: 872-8. PMID 19525944 DOI: 10.1038/Nn.2341 |
0.632 |
|
| 2009 |
Traynelis S, Orr A. O.093 Control of microglial motility by purinergic receptors Parkinsonism & Related Disorders. 15: S24-S25. DOI: 10.1016/S1353-8020(09)70108-7 |
0.605 |
|
| 2008 |
Mannaioni G, Orr AG, Hamill CE, Yuan H, Pedone KH, McCoy KL, Berlinguer Palmini R, Junge CE, Lee CJ, Yepes M, Hepler JR, Traynelis SF. Plasmin potentiates synaptic N-methyl-D-aspartate receptor function in hippocampal neurons through activation of protease-activated receptor-1. The Journal of Biological Chemistry. 283: 20600-11. PMID 18474593 DOI: 10.1074/Jbc.M803015200 |
0.709 |
|
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