| Year |
Citation |
Score |
| 2024 |
Kashyap SN, Fox SN, Wilson KI, Murchison CF, Ambaw YA, Walther TC, Farese RV, Arrant AE, Roberson ED. Carboxy-terminal blockade of sortilin binding enhances progranulin gene therapy, a potential treatment for frontotemporal dementia. Biorxiv : the Preprint Server For Biology. PMID 39345608 DOI: 10.1101/2024.09.15.613118 |
0.791 |
|
| 2024 |
Dean HB, Greer RA, Yang SZ, Elston DS, Brett TJ, Roberson ED, Song Y. Multimerization of TREM2 is impaired by Alzheimer's disease-associated variants. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39032157 DOI: 10.1002/alz.14124 |
0.799 |
|
| 2024 |
Voskobiynyk Y, Li Z, Cochran JN, Davis MN, Carullo NVN, Creed RB, Buckingham SC, Hall AM, Wilson SM, Roberson ED. Excitoprotective effects of conditional tau reduction in excitatory neurons and in adulthood. Biorxiv : the Preprint Server For Biology. PMID 38798487 DOI: 10.1101/2024.05.14.594246 |
0.809 |
|
| 2023 |
Roth JR, Rush T, Thompson SJ, Aldaher AR, Dunn TB, Mesina JS, Cochran JN, Boyle NR, Dean HB, Yang Z, Pathak V, Ruiz P, Wu M, Day JJ, Bostwick JR, ... ... Roberson ED, et al. Development of small-molecule Tau-SH3 interaction inhibitors that prevent amyloid-β toxicity and network hyperexcitability. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 21: e00291. PMID 38241154 DOI: 10.1016/j.neurot.2023.10.001 |
0.777 |
|
| 2023 |
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Roberson ED, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311 |
0.556 |
|
| 2023 |
Zhang L, Flagan TM, Häkkinen S, Chu SA, Brown JA, Lee AJ, Pasquini L, Mandelli ML, Gorno-Tempini ML, Sturm VE, Yokoyama JS, Appleby BS, Cobigo Y, Dickerson BC, Domoto-Reilly K, ... ... Roberson ED, et al. Network connectivity alterations across the MAPT mutation clinical spectrum. Annals of Neurology. PMID 37431188 DOI: 10.1002/ana.26738 |
0.533 |
|
| 2023 |
Kurnellas M, Mitra A, Schwabe T, Paul R, Arrant AE, Roberson ED, Ward M, Yeh F, Long H, Rosenthal A. Latozinemab, a novel progranulin-elevating therapy for frontotemporal dementia. Journal of Translational Medicine. 21: 387. PMID 37322482 DOI: 10.1186/s12967-023-04251-y |
0.748 |
|
| 2023 |
Wright CA, Taylor JW, Cochran M, Lawlor JMJ, Moyers BA, Amaral MD, Bonnstetter ZT, Carter P, Solomon V, Myers RM, Love MN, Geldmacher DS, Cooper SJ, Roberson ED, Cochran JN. Contributions of rare and common variation to early-onset and atypical dementia risk. Cold Spring Harbor Molecular Case Studies. PMID 37308299 DOI: 10.1101/mcs.a006271 |
0.741 |
|
| 2023 |
Wright CA, Taylor JW, Cochran M, Lawlor JMJ, Moyers BA, Amaral MD, Bonnstetter ZT, Carter P, Solomon V, Myers RM, Love MN, Geldmacher DS, Cooper SJ, Roberson ED, Cochran JN. Contributions of rare and common variation to early-onset and atypical dementia risk. Medrxiv : the Preprint Server For Health Sciences. PMID 36798301 DOI: 10.1101/2023.02.06.23285383 |
0.741 |
|
| 2023 |
Kashyap SN, Boyle NR, Roberson ED. Preclinical Interventions in Mouse Models of Frontotemporal Dementia Due to Progranulin Mutations. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 36781744 DOI: 10.1007/s13311-023-01348-6 |
0.795 |
|
| 2022 |
Staffaroni AM, Quintana M, Wendelberger B, Heuer HW, Russell LL, Cobigo Y, Wolf A, Goh SM, Petrucelli L, Gendron TF, Heller C, Clark AL, Taylor JC, Wise A, Ong E, ... ... Roberson ED, et al. Temporal order of clinical and biomarker changes in familial frontotemporal dementia. Nature Medicine. PMID 36138153 DOI: 10.1038/s41591-022-01942-9 |
0.567 |
|
| 2022 |
Gannon M, Wang B, Stringfellow SA, Quintin S, Mendoza I, Srikantha T, Roberts AC, Saito T, Saido TC, Roberson E, Yacoubian TA. 14-3-3θ does not protect against behavioral or pathological deficits in Alzheimer's disease mouse models. Eneuro. PMID 35697511 DOI: 10.1523/ENEURO.0368-21.2022 |
0.355 |
|
| 2022 |
Shao E, Chang CW, Li Z, Yu X, Ho K, Zhang M, Wang X, Simms J, Lo I, Speckart J, Holtzman J, Yu GQ, Roberson ED, Mucke L. TAU ablation in excitatory neurons and postnatal TAU knockdown reduce epilepsy, SUDEP, and autism behaviors in a Dravet syndrome model. Science Translational Medicine. 14: eabm5527. PMID 35476595 DOI: 10.1126/scitranslmed.abm5527 |
0.651 |
|
| 2021 |
Danila MI, Allison JJ, Goins KV, Chiriboga G, Fischer M, Puliafico M, Mudano AS, Rahn EJ, Merchant J, Lawrence CE, Dunkel L, Israel T, Barton B, Jenoure F, Alexander T, ... ... Roberson ED, et al. Development of a multi-component intervention to promote participation of Black and Latinx individuals in biomedical research. Journal of Clinical and Translational Science. 5: e134. PMID 34367678 DOI: 10.1017/cts.2021.797 |
0.644 |
|
| 2021 |
Fusilier AR, Davis JA, Paul JR, Yates SD, McMeekin LJ, Goode LK, Mokashi MV, Remiszewski N, van Groen T, Cowell RM, McMahon LL, Roberson ED, Gamble KL. Dysregulated clock gene expression and abnormal diurnal regulation of hippocampal inhibitory transmission and spatial memory in a mouse model of Alzheimer's disease. Neurobiology of Disease. 105454. PMID 34333153 DOI: 10.1016/j.nbd.2021.105454 |
0.759 |
|
| 2021 |
Salloway S, Farlow M, McDade E, Clifford DB, Wang G, Llibre-Guerra JJ, Hitchcock JM, Mills SL, Santacruz AM, Aschenbrenner AJ, Hassenstab J, Benzinger TLS, Gordon BA, Fagan AM, Coalier KA, ... ... Roberson ED, et al. A trial of gantenerumab or solanezumab in dominantly inherited Alzheimer's disease. Nature Medicine. PMID 34155411 DOI: 10.1038/s41591-021-01369-8 |
0.599 |
|
| 2021 |
Raman F, Fang YD, Grandhi S, Murchison CF, Kennedy RE, Morris JC, Massoumzadeh P, Benzinger T, Roberson ED, McConathy J. Dynamic Amyloid PET: Relationships to Flortaucipir Tau PET Measures. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 34049986 DOI: 10.2967/jnumed.120.254490 |
0.787 |
|
| 2021 |
Rojas JC, Wang P, Staffaroni AM, Heller C, Cobigo Y, Wolf A, Goh SM, Ljubenkov PA, Heuer HW, Fong JC, Taylor JB, Veras E, Song L, Jeromin A, Hanlon D, ... ... Roberson ED, et al. Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration. Neurology. PMID 33827960 DOI: 10.1212/WNL.0000000000011848 |
0.545 |
|
| 2021 |
Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, ... Roberson ED, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 131. PMID 33792567 DOI: 10.1172/JCI149564 |
0.611 |
|
| 2021 |
Voskobiynyk Y, Battu G, Felker SA, Cochran JN, Newton MP, Lambert LJ, Kesterson RA, Myers RM, Cooper GM, Roberson ED, Barsh GS. Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy. Plos Genetics. 17: e1009195. PMID 33411788 DOI: 10.1371/journal.pgen.1009195 |
0.785 |
|
| 2020 |
Murchison CF, Kennedy RE, McConathy JE, Roberson ED. Racial Differences in Alzheimer's Disease Specialist Encounters are Associated with Usage of Molecular Imaging and Dementia Medications: An Enterprise-Wide Analysis Using i2b2. Journal of Alzheimer's Disease : Jad. PMID 33337364 DOI: 10.3233/JAD-200796 |
0.601 |
|
| 2020 |
Chu SA, Flagan TM, Staffaroni AM, Jiskoot LC, Deng J, Spina S, Zhang L, Sturm VE, Yokoyama JS, Seeley WW, Papma JM, Geschwind DH, Rosen HJ, Boeve BF, Boxer AL, ... ... Roberson ED, et al. Brain volumetric deficits in MAPT mutation carriers: a multisite study. Annals of Clinical and Translational Neurology. PMID 33247623 DOI: 10.1002/acn3.51249 |
0.538 |
|
| 2020 |
Lawrence CE, Dunkel L, McEver M, Israel T, Taylor R, Chiriboga G, Goins KV, Rahn EJ, Mudano AS, Roberson ED, Chambless C, Wadley VG, Danila MI, Fischer MA, Joosten Y, et al. A REDCap-based model for electronic consent (eConsent): Moving toward a more personalized consent. Journal of Clinical and Translational Science. 4: 345-353. PMID 33244416 DOI: 10.1017/cts.2020.30 |
0.65 |
|
| 2020 |
Arrant AE, Davis SE, Vollmer RM, Murchison CF, Mobley JA, Nana AL, Spina S, Grinberg LT, Karydas AM, Miller BL, Seeley WW, Roberson ED. Elevated levels of extracellular vesicles in progranulin-deficient mice and FTD-GRN Patients. Annals of Clinical and Translational Neurology. PMID 33197149 DOI: 10.1002/acn3.51242 |
0.807 |
|
| 2020 |
Kober DL, Stuchell-Brereton MD, Kluender CE, Dean HB, Strickland MR, Steinberg DF, Nelson SS, Baban B, Holtzman DM, Frieden C, Alexander-Brett J, Roberson ED, Song Y, Brett TJ. Functional insights from biophysical study of TREM2 interactions with apoE and Aβ. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33090700 DOI: 10.1002/alz.12194 |
0.769 |
|
| 2020 |
Voskobiynyk Y, Roth JR, Cochran JN, Rush T, Carullo NV, Mesina JS, Waqas M, Vollmer RM, Day JJ, McMahon LL, Roberson ED. Alzheimer's disease risk gene induces Tau-dependent network hyperexcitability. Elife. 9. PMID 32657270 DOI: 10.7554/Elife.57354 |
0.804 |
|
| 2020 |
Toller G, Ranasinghe K, Cobigo Y, Staffaroni A, Appleby B, Brushaber D, Coppola G, Dickerson B, Domoto-Reilly K, Fields J, Fong J, Forsberg L, Ghoshal N, Graff-Radford N, Grossman M, ... ... Roberson E, et al. Revised Self-Monitoring Scale: A potential endpoint for frontotemporal dementia clinical trials. Neurology. PMID 32371446 DOI: 10.1212/Wnl.0000000000009451 |
0.388 |
|
| 2020 |
Cochran JN, Geier EG, Bonham LW, Newberry JS, Amaral MD, Thompson ML, Lasseigne BN, Karydas AM, Roberson ED, Cooper GM, Rabinovici GD, Miller BL, Myers RM, Yokoyama JS. Non-Coding and Loss-of-Function Coding Variants in TET2 are Associated with Multiple Neurodegenerative Diseases. American Journal of Human Genetics. PMID 32330418 DOI: 10.1016/J.Ajhg.2020.03.010 |
0.782 |
|
| 2020 |
Zhang F, Gannon M, Chen Y, Yan S, Zhang S, Feng W, Tao J, Sha B, Liu Z, Saito T, Saido T, Keene CD, Jiao K, Roberson ED, Xu H, et al. β-amyloid redirects norepinephrine signaling to activate the pathogenic GSK3β/tau cascade. Science Translational Medicine. 12. PMID 31941827 DOI: 10.1126/Scitranslmed.Aay6931 |
0.321 |
|
| 2020 |
Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, ... ... Roberson ED, et al. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 11-21. PMID 31914230 DOI: 10.1016/J.Jalz.2019.01.012 |
0.334 |
|
| 2020 |
Heuer HW, Wang P, Rascovsky K, Wolf A, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber DE, Caso C, Coppola G, Dickerson B, Dickinson S, Domoto-Reilly K, Faber K, ... ... Roberson ED, et al. Comparison of sporadic and familial behavioral variant frontotemporal dementia (FTD) in a North American cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 60-70. PMID 31914226 DOI: 10.1002/Alz.12046 |
0.455 |
|
| 2020 |
Ramos EM, Dokuru DR, Van Berlo V, Wojta K, Wang Q, Huang AY, Deverasetty S, Qin Y, van Blitterswijk M, Jackson J, Appleby B, Bordelon Y, Brannelly P, Brushaber DE, Dickerson B, ... ... Roberson ED, et al. Genetic screening of a large series of North American sporadic and familial frontotemporal dementia cases. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 118-130. PMID 31914217 DOI: 10.1002/Alz.12011 |
0.33 |
|
| 2020 |
Narasimhan S, Changolkar L, Riddle DM, Kats A, Stieber A, Weitzman SA, Zhang B, Li Z, Roberson ED, Trojanowski JQ, Lee VMY. Human tau pathology transmits glial tau aggregates in the absence of neuronal tau. The Journal of Experimental Medicine. 217. PMID 31826239 DOI: 10.1084/Jem.20190783 |
0.471 |
|
| 2019 |
Dean HB, Roberson ED, Song Y. Neurodegenerative Disease-Associated Variants in TREM2 Destabilize the Apical Ligand-Binding Region of the Immunoglobulin Domain. Frontiers in Neurology. 10: 1252. PMID 32021611 DOI: 10.3389/Fneur.2019.01252 |
0.796 |
|
| 2019 |
Arrant AE, Roth JR, Boyle NR, Kashyap SN, Hoffmann MQ, Murchison CF, Ramos EM, Nana AL, Spina S, Grinberg LT, Miller BL, Seeley WW, Roberson ED. Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathologica Communications. 7: 218. PMID 31870439 DOI: 10.1186/S40478-019-0872-6 |
0.781 |
|
| 2019 |
Cochran JN, McKinley EC, Cochran M, Amaral MD, Moyers BA, Lasseigne BN, Gray DE, Lawlor JMJ, Prokop JW, Geier EG, Holt JM, Thompson ML, Newberry JS, Yokoyama JS, Worthey EA, ... ... Roberson ED, et al. Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles. Cold Spring Harbor Molecular Case Studies. 5. PMID 31836585 DOI: 10.1101/mcs.a003491 |
0.734 |
|
| 2019 |
Olney NT, Ong E, Goh SM, Bajorek L, Dever R, Staffaroni AM, Cobigo Y, Bock M, Chiang K, Ljubenkov P, Kornak J, Heuer HW, Wang P, Rascovsky K, Wolf A, ... ... Roberson ED, et al. Clinical and volumetric changes with increasing functional impairment in familial frontotemporal lobar degeneration. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31784375 DOI: 10.1016/J.Jalz.2019.08.196 |
0.332 |
|
| 2019 |
Tsai RM, Miller Z, Koestler M, Rojas JC, Ljubenkov PA, Rosen HJ, Rabinovici GD, Fagan AM, Cobigo Y, Brown JA, Jung JI, Hare E, Geldmacher DS, Natelson-Love M, McKinley EC, ... ... Roberson ED, et al. Reactions to Multiple Ascending Doses of the Microtubule Stabilizer TPI-287 in Patients With Alzheimer Disease, Progressive Supranuclear Palsy, and Corticobasal Syndrome: A Randomized Clinical Trial. Jama Neurology. PMID 31710340 DOI: 10.1001/Jamaneurol.2019.3812 |
0.512 |
|
| 2019 |
Rush T, Roth JR, Thompson SJ, Aldaher AR, Cochran JN, Roberson ED. A peptide inhibitor of Tau-SH3 interactions ameliorates amyloid-β toxicity. Neurobiology of Disease. 104668. PMID 31698056 DOI: 10.1016/J.Nbd.2019.104668 |
0.81 |
|
| 2019 |
Sohn PD, Huang CT, Yan R, Fan L, Tracy TE, Camargo CM, Montgomery KM, Arhar T, Mok SA, Freilich R, Baik J, He M, Gong S, Roberson ED, Karch CM, et al. Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron. PMID 31542321 DOI: 10.1016/J.Neuron.2019.08.008 |
0.301 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Roberson ED, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7 |
0.563 |
|
| 2019 |
Raman F, Grandhi S, Murchison CF, Kennedy RE, Landau S, Roberson ED, McConathy J. Biomarker Localization, Analysis, Visualization, Extraction, and Registration (BLAzER) Methodology for Research and Clinical Brain PET Applications. Journal of Alzheimer's Disease : Jad. PMID 31322571 DOI: 10.3233/JAD-190329 |
0.768 |
|
| 2019 |
Staffaroni AM, Cobigo Y, Goh SM, Kornak J, Bajorek L, Chiang K, Appleby B, Bove J, Bordelon Y, Brannelly P, Brushaber D, Caso C, Coppola G, Dever R, Dheel C, ... ... Roberson ED, et al. Individualized atrophy scores predict dementia onset in familial frontotemporal lobar degeneration. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31272932 DOI: 10.1016/J.Jalz.2019.04.007 |
0.306 |
|
| 2019 |
Staffaroni AM, Bajorek L, Casaletto KB, Cobigo Y, Goh SM, Wolf A, Heuer HW, Elahi FM, Ljubenkov PA, Dever R, Kornak J, Appleby B, Bove J, Bordelon Y, Brannelly P, ... ... Roberson ED, et al. Assessment of executive function declines in presymptomatic and mildly symptomatic familial frontotemporal dementia: NIH-EXAMINER as a potential clinical trial endpoint. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 31088775 DOI: 10.1016/j.jalz.2019.01.012 |
0.334 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Roberson ED, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
0.564 |
|
| 2019 |
Murchison CF, Kennedy RE, McConathy J, Roberson ED. P3-497: VARIATIONS IN REFERRALS, ASSESSMENTS AND TREATMENT OF ALZHEIMER'S DISEASE FOR AFRICAN AMERICANS IN THE DEEP SOUTH Alzheimer's & Dementia. 15: P1159-P1159. DOI: 10.1016/j.jalz.2019.06.3532 |
0.557 |
|
| 2019 |
Cochran ME, Cochran JN, McKinley E, Amaral MD, Moyer B, Lasseigne BN, Gray D, Lawlor JM, Prokop J, Newberry JS, Worthey EA, Geldmacher DS, Natelson Love MC, Myers RM, Roberson ED. P3-143: UTILITY OF GENOMIC SEQUENCING IN CASES OF EARLY-ONSET AND FAMILIAL DEMENTIA Alzheimer's & Dementia. 15: P986-P986. DOI: 10.1016/J.Jalz.2019.06.3171 |
0.398 |
|
| 2019 |
Dean HB, Roberson ED, Song Y. The Effects of Common Disease-Causing Variations on the Structure and Stability of TREM2: An In Silico Examination Biophysical Journal. 116: 471a. DOI: 10.1016/J.Bpj.2018.11.2544 |
0.768 |
|
| 2018 |
Arrant AE, Filiano AJ, Patel AR, Hoffmann MQ, Boyle NR, Kashyap SN, Onyilo VC, Young AH, Roberson ED. Reduction of microglial progranulin does not exacerbate pathology or behavioral deficits in neuronal progranulin-insufficient mice. Neurobiology of Disease. PMID 30448285 DOI: 10.1016/J.Nbd.2018.11.011 |
0.787 |
|
| 2018 |
Arrant AE, Nicholson AM, Zhou X, Rademakers R, Roberson ED. Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency. Molecular Neurodegeneration. 13: 32. PMID 29929528 DOI: 10.1186/S13024-018-0264-6 |
0.739 |
|
| 2018 |
Arrant AE, Onyilo VC, Unger DE, Roberson ED. Progranulin Gene Therapy Improves Lysosomal Dysfunction and Microglial Pathology Associated with Frontotemporal Dementia and Neuronal Ceroid Lipofuscinosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29378861 DOI: 10.1523/Jneurosci.3081-17.2018 |
0.766 |
|
| 2017 |
Schonhaut DR, McMillan CT, Spina S, Dickerson BC, Siderowf A, Devous MD, Tsai R, Winer J, Russell DS, Litvan I, Roberson ED, Seeley WW, Grinberg LT, Kramer JH, Miller BL, et al. (18) F-flortaucipir tau PET distinguishes established progressive supranuclear palsy from controls and Parkinson's disease: A multicenter study. Annals of Neurology. PMID 28980714 DOI: 10.1002/Ana.25060 |
0.623 |
|
| 2017 |
Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Roberson ED, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
0.547 |
|
| 2017 |
Arrant AE, Filiano AJ, Unger DE, Young AH, Roberson ED. Restoring neuronal progranulin reverses deficits in a mouse model of frontotemporal dementia. Brain : a Journal of Neurology. PMID 28379303 DOI: 10.1093/Brain/Awx060 |
0.818 |
|
| 2016 |
Natelson Love M, Clark DG, Cochran JN, Den Beste KA, Geldmacher DS, Benzinger TL, Gordon BA, Morris JC, Bateman RJ, Roberson ED. Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease. Neurobiology of Aging. PMID 27793474 DOI: 10.1016/J.Neurobiolaging.2016.09.020 |
0.727 |
|
| 2016 |
Vossel KA, Ranasinghe KG, Beagle AJ, Mizuiri D, Honma SM, Dowling AF, Darwish SM, Van Berlo V, Barnes DE, Mantle M, Karydas AM, Coppola G, Roberson ED, Miller BL, Garcia PA, et al. Incidence and Impact of Subclinical Epileptiform Activity in Alzheimer's Disease. Annals of Neurology. PMID 27696483 DOI: 10.1002/Ana.24794 |
0.587 |
|
| 2016 |
Arrant AE, Filiano AJ, Warmus BA, Hall AM, Roberson ED. Progranulin haploinsufficiency causes biphasic social dominance abnormalities in the tube test. Genes, Brain, and Behavior. PMID 27213486 DOI: 10.1111/Gbb.12300 |
0.774 |
|
| 2015 |
Kimbrough IF, Robel S, Roberson ED, Sontheimer H. Vascular amyloidosis impairs the gliovascular unit in a mouse model of Alzheimer's disease. Brain : a Journal of Neurology. 138: 3716-33. PMID 26598495 DOI: 10.1016/J.Jalz.2015.07.267 |
0.326 |
|
| 2015 |
Arrant AE, Patel AR, Roberson ED. Effects of Exercise on Progranulin Levels and Gliosis in Progranulin-Insufficient Mice. Eneuro. 2. PMID 26361634 DOI: 10.1523/ENEURO.0061-14.2015 |
0.703 |
|
| 2015 |
Cochran JN, Rush T, Buckingham SC, Roberson ED. The Alzheimer's disease risk factor CD2AP maintains blood-brain barrier integrity. Human Molecular Genetics. PMID 26358779 DOI: 10.1093/hmg/ddv371 |
0.774 |
|
| 2015 |
Gannon M, Che P, Chen Y, Jiao K, Roberson ED, Wang Q. Noradrenergic dysfunction in Alzheimer's disease. Frontiers in Neuroscience. 9: 220. PMID 26136654 DOI: 10.3389/fnins.2015.00220 |
0.308 |
|
| 2015 |
Hall AM, Throesch BT, Buckingham SC, Markwardt SJ, Peng Y, Wang Q, Hoffman DA, Roberson ED. Tau-dependent Kv4.2 depletion and dendritic hyperexcitability in a mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 6221-30. PMID 25878292 DOI: 10.1523/Jneurosci.2552-14.2015 |
0.608 |
|
| 2015 |
Day JJ, Roberson ED. DNA methylation slows effects of C9orf72 mutations: An epigenetic brake on genetic inheritance. Neurology. 84: 1616-7. PMID 25795647 DOI: 10.1212/WNL.0000000000001504 |
0.545 |
|
| 2015 |
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Roberson ED, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157 |
0.665 |
|
| 2015 |
Cochran JN, Rush T, Warmus BA, Franklin AV, McMahon LL, Roberson ED. P4-196: The Alzheimer's disease risk gene bin1 regulates neuronal excitability Alzheimer's & Dementia. 11: P855-P855. DOI: 10.1016/J.Jalz.2015.08.024 |
0.799 |
|
| 2014 |
Arrant AE, Roberson ED. MicroRNA-124 modulates social behavior in frontotemporal dementia. Nature Medicine. 20: 1381-3. PMID 25473917 DOI: 10.1038/Nm.3768 |
0.708 |
|
| 2014 |
Warmus BA, Sekar DR, McCutchen E, Schellenberg GD, Roberts RC, McMahon LL, Roberson ED. Tau-mediated NMDA receptor impairment underlies dysfunction of a selectively vulnerable network in a mouse model of frontotemporal dementia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 16482-95. PMID 25471585 DOI: 10.1523/Jneurosci.3418-14.2014 |
0.811 |
|
| 2014 |
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Roberson ED, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491 |
0.638 |
|
| 2014 |
Cochran JN, Diggs PV, Nebane NM, Rasmussen L, White EL, Bostwick R, Maddry JA, Suto MJ, Roberson ED. AlphaScreen HTS and live-cell bioluminescence resonance energy transfer (BRET) assays for identification of Tau-Fyn SH3 interaction inhibitors for Alzheimer disease. Journal of Biomolecular Screening. 19: 1338-49. PMID 25156556 DOI: 10.1177/1087057114547232 |
0.732 |
|
| 2014 |
Ward ME, Taubes A, Chen R, Miller BL, Sephton CF, Gelfand JM, Minami S, Boscardin J, Martens LH, Seeley WW, Yu G, Herz J, Filiano AJ, Arrant AE, Roberson ED, et al. Early retinal neurodegeneration and impaired Ran-mediated nuclear import of TDP-43 in progranulin-deficient FTLD. The Journal of Experimental Medicine. 211: 1937-45. PMID 25155018 DOI: 10.1084/Jem.20140214 |
0.812 |
|
| 2014 |
Li Z, Hall AM, Kelinske M, Roberson ED. Seizure resistance without parkinsonism in aged mice after tau reduction. Neurobiology of Aging. 35: 2617-24. PMID 24908165 DOI: 10.1016/J.Neurobiolaging.2014.05.001 |
0.668 |
|
| 2014 |
Boxer AL, Lang AE, Grossman M, Knopman DS, Miller BL, Schneider LS, Doody RS, Lees A, Golbe LI, Williams DR, Corvol JC, Ludolph A, Burn D, Lorenzl S, Litvan I, ... Roberson ED, et al. Davunetide in patients with progressive supranuclear palsy: a randomised, double-blind, placebo-controlled phase 2/3 trial. The Lancet. Neurology. 13: 676-85. PMID 24873720 DOI: 10.1016/S1474-4422(14)70088-2 |
0.341 |
|
| 2014 |
Qiu H, Lee S, Shang Y, Wang WY, Au KF, Kamiya S, Barmada SJ, Finkbeiner S, Lui H, Carlton CE, Tang AA, Oldham MC, Wang H, Shorter J, Filiano AJ, ... Roberson ED, et al. ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects. The Journal of Clinical Investigation. 124: 981-99. PMID 24509083 DOI: 10.1172/Jci72723 |
0.666 |
|
| 2014 |
Cochran JN, Hall AM, Roberson ED. The dendritic hypothesis for Alzheimer's disease pathophysiology. Brain Research Bulletin. 103: 18-28. PMID 24333192 DOI: 10.1016/J.Brainresbull.2013.12.004 |
0.786 |
|
| 2013 |
Filiano AJ, Martens LH, Young AH, Warmus BA, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang EJ, Gao FB, Farese RV, Roberson ED. Dissociation of frontotemporal dementia-related deficits and neuroinflammation in progranulin haploinsufficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 5352-61. PMID 23516300 DOI: 10.1523/Jneurosci.6103-11.2013 |
0.809 |
|
| 2013 |
Seward ME, Swanson E, Norambuena A, Reimann A, Cochran JN, Li R, Roberson ED, Bloom GS. Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease. Journal of Cell Science. 126: 1278-86. PMID 23345405 DOI: 10.1242/Jcs.1125880 |
0.75 |
|
| 2013 |
Boxer AL, Gold M, Huey E, Hu WT, Rosen H, Kramer J, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, ... ... Roberson ED, et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: the next therapeutic frontier). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 189-98. PMID 23062850 DOI: 10.1016/J.Jalz.2012.03.003 |
0.7 |
|
| 2013 |
Boxer AL, Gold M, Huey E, Gao FB, Burton EA, Chow T, Kao A, Leavitt BR, Lamb B, Grether M, Knopman D, Cairns NJ, Mackenzie IR, Mitic L, Roberson ED, et al. Frontotemporal degeneration, the next therapeutic frontier: molecules and animal models for frontotemporal degeneration drug development. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 9: 176-88. PMID 23043900 DOI: 10.1016/J.Jalz.2012.03.002 |
0.708 |
|
| 2012 |
Jin YN, Chen PC, Watson JA, Walters BJ, Phillips SE, Green K, Schmidt R, Wilson JA, Johnson GV, Roberson ED, Dobrunz LE, Wilson SM. Usp14 deficiency increases tau phosphorylation without altering tau degradation or causing tau-dependent deficits. Plos One. 7: e47884. PMID 23144711 DOI: 10.1371/Journal.Pone.0047884 |
0.327 |
|
| 2012 |
Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Roberson ED, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801 |
0.633 |
|
| 2012 |
Hall AM, Roberson ED. Mouse models of Alzheimer's disease. Brain Research Bulletin. 88: 3-12. PMID 22142973 DOI: 10.1016/J.Brainresbull.2011.11.017 |
0.603 |
|
| 2012 |
Filiano A, Martens LH, Young A, Warmus B, Zhou P, Diaz-Ramirez G, Jiao J, Zhang Z, Huang E, Gao F, Farese R, Roberson E. O1-05-03: Neuronal effects of progranulin deficiency contribute to frontotemporal dementia independent of neuroinflammation Alzheimer's & Dementia. 8: P93-P93. DOI: 10.1016/J.Jalz.2012.05.228 |
0.787 |
|
| 2012 |
Seward M, Swanson E, Roberson E, Bloom G. S5-01-01: The pathway from amyloid to tau for aberrant neuronal cell cycle re-entry in Alzheimer's disease Alzheimer's & Dementia. 8: P724-P724. DOI: 10.1016/J.Jalz.2012.05.1943 |
0.421 |
|
| 2012 |
Vossel KA, Beagle A, Hegde M, Mantle M, Kirsch H, Garcia P, Honma S, Findlay A, Rabinovici G, Jagust W, Nagarajan S, Miller B, Roberson E, Mucke L. P2-377: Subclinical epileptiform activity in Alzheimer's disease Alzheimer's & Dementia. 8: P395-P396. DOI: 10.1016/J.Jalz.2012.05.1087 |
0.695 |
|
| 2011 |
Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Roberson ED, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801 |
0.583 |
|
| 2011 |
Roberson ED, Halabisky B, Yoo JW, Yao J, Chin J, Yan F, Wu T, Hamto P, Devidze N, Yu GQ, Palop JJ, Noebels JL, Mucke L. Amyloid-β/Fyn-induced synaptic, network, and cognitive impairments depend on tau levels in multiple mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 700-11. PMID 21228179 DOI: 10.1523/Jneurosci.4152-10.2011 |
0.605 |
|
| 2011 |
Palop JJ, Mucke L, Roberson ED. Quantifying biomarkers of cognitive dysfunction and neuronal network hyperexcitability in mouse models of Alzheimer's disease: depletion of calcium-dependent proteins and inhibitory hippocampal remodeling. Methods in Molecular Biology (Clifton, N.J.). 670: 245-62. PMID 20967595 DOI: 10.1007/978-1-60761-744-0_17 |
0.576 |
|
| 2010 |
Rabinovici GD, Roberson ED. Beyond diagnosis: what biomarkers are teaching us about the "bio"logy of Alzheimer disease. Annals of Neurology. 67: 283-5. PMID 20373338 DOI: 10.1002/ana.22020 |
0.462 |
|
| 2009 |
Roberson ED, Kao AW. Animal models of dementia The Behavioral Neurology of Dementia. 131-141. DOI: 10.1017/CBO9780511581410.010 |
0.647 |
|
| 2008 |
Meilandt WJ, Yu GQ, Chin J, Roberson ED, Palop JJ, Wu T, Scearce-Levie K, Mucke L. Enkephalin elevations contribute to neuronal and behavioral impairments in a transgenic mouse model of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 5007-17. PMID 18463254 DOI: 10.1523/Jneurosci.0590-08.2008 |
0.606 |
|
| 2008 |
Scearce-Levie K, Roberson ED, Gerstein H, Cholfin JA, Mandiyan VS, Shah NM, Rubenstein JL, Mucke L. Abnormal social behaviors in mice lacking Fgf17. Genes, Brain, and Behavior. 7: 344-54. PMID 17908176 DOI: 10.1111/j.1601-183X.2007.00357.x |
0.493 |
|
| 2008 |
Roberson ED, Meilandt WJ, Yao J, Yoo J, Noebels JL, Mucke L. P1-062: Tau reduction prevents epileptiform activity in a mouse model of Alzheimer's disease: Gene expression microarray analysis Alzheimer's & Dementia. 4: T224-T224. DOI: 10.1016/j.jalz.2008.05.648 |
0.568 |
|
| 2007 |
Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu GQ, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L. Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer's disease. Neuron. 55: 697-711. PMID 17785178 DOI: 10.1016/J.Neuron.2007.07.025 |
0.604 |
|
| 2007 |
Roberson ED, Scearce-Levie K, Palop JJ, Yan F, Cheng IH, Wu T, Gerstein H, Yu GQ, Mucke L. Reducing endogenous tau ameliorates amyloid beta-induced deficits in an Alzheimer's disease mouse model. Science (New York, N.Y.). 316: 750-4. PMID 17478722 DOI: 10.1126/Science.1141736 |
0.598 |
|
| 2006 |
Roberson ED, Mucke L. 100 years and counting: prospects for defeating Alzheimer's disease. Science (New York, N.Y.). 314: 781-4. PMID 17082448 DOI: 10.1126/science.1132813 |
0.588 |
|
| 2006 |
Mueller-Steiner S, Zhou Y, Arai H, Roberson ED, Sun B, Chen J, Wang X, Yu G, Esposito L, Mucke L, Gan L. Antiamyloidogenic and neuroprotective functions of cathepsin B: implications for Alzheimer's disease. Neuron. 51: 703-14. PMID 16982417 DOI: 10.1016/J.Neuron.2006.07.027 |
0.565 |
|
| 2006 |
Arrant AE, Onyilo VC, Unger DE, Roberson ED. O4-05-01: PROGRANULIN GENE THERAPY IMPROVES PATHOLOGY AND REVERSES SOCIAL DEFICITS IN MOUSE MODELS OF FRONTOTEMPORAL DEMENTIA AND NEURONAL CEROID LIPOFUSCINOSIS DUE TO PROGRANULIN MUTATIONS Alzheimer's & Dementia. 14: P1411-P1411. DOI: 10.1016/J.Jalz.2018.06.2933 |
0.737 |
|
| 2006 |
Voskobiynyk Y, Cochran JN, Rush T, Roth JR, Roberson ED. P3-106: THE ALZHEIMER'S DISEASE RISK GENE BIN1 REGULATES NETWORK HYPEREXCITABILITY Alzheimer's & Dementia. 14: P1108-P1108. DOI: 10.1016/J.Jalz.2018.06.1463 |
0.79 |
|
| 2006 |
Roberson ED, Scearce-Levie K, Yan F, Yu G, Mucke L. O2-04-05: Reducing endogenous tau prevents APP/Aβ-induced deficits in a mouse model of Alzheimer's disease Alzheimer's & Dementia. 2: S38-S38. DOI: 10.1016/j.jalz.2006.05.133 |
0.58 |
|
| 2005 |
Roberson ED, Hesse JH, Rose KD, Slama H, Johnson JK, Yaffe K, Forman MS, Miller CA, Trojanowski JQ, Kramer JH, Miller BL. Frontotemporal dementia progresses to death faster than Alzheimer disease. Neurology. 65: 719-25. PMID 16157905 DOI: 10.1212/01.Wnl.0000173837.82820.9F |
0.57 |
|
| 2005 |
Johnson JK, Diehl J, Mendez MF, Neuhaus J, Shapira JS, Forman M, Chute DJ, Roberson ED, Pace-Savitsky C, Neumann M, Chow TW, Rosen HJ, Forstl H, Kurz A, Miller BL. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Archives of Neurology. 62: 925-30. PMID 15956163 DOI: 10.1001/Archneur.62.6.925 |
0.378 |
|
| 2001 |
Roberson ED, Sweatt JD. Memory-forming chemical reactions. Reviews in the Neurosciences. 12: 41-50. PMID 11236064 DOI: 10.1515/Revneuro.2001.12.1.41 |
0.414 |
|
| 2000 |
Adams JP, Roberson ED, English JD, Selcher JC, Sweatt JD. MAPK regulation of gene expression in the central nervous system. Acta Neurobiologiae Experimentalis. 60: 377-94. PMID 11016081 |
0.768 |
|
| 1999 |
Roberson ED, Sweatt JD. A biochemical blueprint for long-term memory. Learning & Memory (Cold Spring Harbor, N.Y.). 6: 381-8. PMID 10509708 DOI: 10.1101/Lm.6.4.381 |
0.434 |
|
| 1999 |
Roberson ED, English JD, Adams JP, Selcher JC, Kondratick C, Sweatt JD. The mitogen-activated protein kinase cascade couples PKA and PKC to cAMP response element binding protein phosphorylation in area CA1 of hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 4337-48. PMID 10341237 DOI: 10.1523/Jneurosci.19-11-04337.1999 |
0.77 |
|
| 1998 |
Sweatt JD, Atkins CM, Johnson J, English JD, Roberson ED, Chen SJ, Newton A, Klann E. Protected-site phosphorylation of protein kinase C in hippocampal long-term potentiation. Journal of Neurochemistry. 71: 1075-85. PMID 9721732 DOI: 10.1046/J.1471-4159.1998.71031075.X |
0.779 |
|
| 1998 |
Matilla A, Roberson ED, Banfi S, Morales J, Armstrong DL, Burright EN, Orr HT, Sweatt JD, Zoghbi HY, Matzuk MM. Mice lacking ataxin-1 display learning deficits and decreased hippocampal paired-pulse facilitation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5508-16. PMID 9651231 DOI: 10.1523/Jneurosci.18-14-05508.1998 |
0.52 |
|
| 1998 |
Klann E, Roberson ED, Knapp LT, Sweatt JD. A role for superoxide in protein kinase C activation and induction of long-term potentiation. The Journal of Biological Chemistry. 273: 4516-22. PMID 9468506 DOI: 10.1074/Jbc.273.8.4516 |
0.617 |
|
| 1996 |
Roberson ED, English JD, Sweatt JD. A biochemist's view of long-term potentiation. Learning & Memory (Cold Spring Harbor, N.Y.). 3: 1-24. PMID 10456072 DOI: 10.1101/Lm.3.1.1 |
0.622 |
|
| 1996 |
Roberson ED, Sweatt JD. Transient activation of cyclic AMP-dependent protein kinase during hippocampal long-term potentiation. The Journal of Biological Chemistry. 271: 30436-41. PMID 8940008 DOI: 10.1074/jbc.271.48.30436 |
0.463 |
|
| 1995 |
Roberson ED, Sweatt JD. Regulation of adenylyl cyclase in LTP Behavioral and Brain Sciences. 18: 485-486. DOI: 10.1017/S0140525X0003942X |
0.414 |
|
| 1992 |
Sessoms JS, Chen SJ, Chetkovich DM, Powell CM, Roberson ED, Sweatt JD, Klann E. Ca(2+)-induced persistent protein kinase C activation in rat hippocampal homogenates. Second Messengers and Phosphoproteins. 14: 109-26. PMID 1345337 |
0.774 |
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