Anat O. Stemmer-Rachamimov, MD, University of Milan - Publications

Affiliations: 
Pathology Masssachusetts General Hospital, Boston, MA, United States 
Area:
Heredetary Brain Tumor Syndrome, NeuropathologyOphthalmic Pathology, Surgicals
Website:
http://www.massgeneral.org/doctors/doctor.aspx?id=17876

160 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Batool SM, Escobedo AK, Hsia T, Ekanayake E, Khanna SK, Gamblin AS, Zheng H, Skog J, Miller JJ, Stemmer-Rachamimov AO, Cahill DP, Balaj L, Carter BS. Clinical utility of a blood based assay for the detection of IDH1.R132H-mutant gliomas. Nature Communications. 15: 7074. PMID 39152110 DOI: 10.1038/s41467-024-51332-7  0.459
2023 Staedtke V, Topilko P, Le LQ, Grimes K, Largaespada DA, Cagan RL, Steensma MR, Stemmer-Rachamimov A, Blakeley JO, Rhodes SD, Ly I, Romo CG, Lee SY, Serra E. Existing and Developing Preclinical Models for Neurofibromatosis Type 1-Related Cutaneous Neurofibromas. The Journal of Investigative Dermatology. PMID 37330719 DOI: 10.1016/j.jid.2023.01.042  0.302
2022 Prabhakar S, Beauchamp RL, Cheah PS, Yoshinaga A, Haidar EA, Lule S, Mani G, Maalouf K, Stemmer-Rachamimov A, Jung DH, Welling DB, Giovannini M, Plotkin SR, Maguire CA, Ramesh V, et al. Gene replacement therapy in a schwannoma mouse model of neurofibromatosis type 2. Molecular Therapy. Methods & Clinical Development. 26: 169-180. PMID 35846573 DOI: 10.1016/j.omtm.2022.06.012  0.362
2022 Freeman SS, Sade-Feldman M, Kim J, Stewart C, Gonye ALK, Ravi A, Arniella MB, Gushterova I, LaSalle TJ, Blaum EM, Yizhak K, Frederick DT, Sharova T, Leshchiner I, Elagina L, ... ... Stemmer-Rachamimov AO, et al. Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma. Cell Reports. Medicine. 3: 100500. PMID 35243413 DOI: 10.1016/j.xcrm.2021.100500  0.321
2021 Chang LS, Oblinger JL, Smith AE, Ferrer M, Angus SP, Hawley E, Petrilli AM, Beauchamp RL, Riecken LB, Erdin S, Poi M, Huang J, Bessler WK, Zhang X, Guha R, ... ... Stemmer-Rachamimov AO, et al. Brigatinib causes tumor shrinkage in both NF2-deficient meningioma and schwannoma through inhibition of multiple tyrosine kinases but not ALK. Plos One. 16: e0252048. PMID 34264955 DOI: 10.1371/journal.pone.0252048  0.319
2020 Li M, Li G, Kiyokawa J, Tirmizi Z, Richardson LG, Ning J, Das S, Martuza RL, Stemmer-Rachamimov A, Rabkin SD, Wakimoto H. Characterization and oncolytic virus targeting of FAP-expressing tumor-associated pericytes in glioblastoma. Acta Neuropathologica Communications. 8: 221. PMID 33308315 DOI: 10.1186/s40478-020-01096-0  0.347
2020 Richardson LG, Nieman LT, Stemmer-Rachamimov AO, Zheng XS, Stafford K, Nagashima H, Miller JJ, Kiyokawa J, Ting DT, Wakimoto H, Cahill DP, Choi BD, Curry WT. IDH-mutant gliomas harbor fewer regulatory T cells in humans and mice. Oncoimmunology. 9: 1806662. PMID 32923170 DOI: 10.1080/2162402X.2020.1806662  0.51
2020 Ortonne N, Carroll SL, Rodriguez FJ, Miller DC, Nazarian RM, Blakeley JO, Madaj ZB, Verma SK, Stemmer-Rachamimov A. Assessing interobserver variability and accuracy in the histological diagnosis and classification of cutaneous neurofibromass. Neuro-Oncology Advances. 2: i117-i123. PMID 32642737 DOI: 10.1093/noajnl/vdz050  0.455
2020 Freeman SS, Sade-Feldman M, Kim J, Stewart C, Ravi A, Arniella M, Yizhak K, Leshchiner I, Elagina L, Spiro O, Livitz D, Rosebrock D, Aguet F, Carrot-Zhang J, Gonye A, ... ... Stemmer-Rachamimov A, et al. Abstract 6670: Combined signals from tumor and immune cells predict outcomes of checkpoint inhibition in melanoma Immunology. 80: 6670-6670. DOI: 10.1158/1538-7445.Am2020-6670  0.393
2019 Prabhakar S, Cheah PS, Zhang X, Zinter M, Gianatasio M, Hudry E, Bronson RT, Kwiatkowski DJ, Stemmer-Rachamimov A, Maguire CA, Sena-Esteves M, Tannous BA, Breakefield XO. Long-Term Therapeutic Efficacy of Intravenous AAV-Mediated Hamartin Replacement in Mouse Model of Tuberous Sclerosis Type 1. Molecular Therapy. Methods & Clinical Development. 15: 18-26. PMID 31534984 DOI: 10.1016/J.Ibror.2019.07.1575  0.362
2019 Sagers JE, Sahin MI, Moon I, Ahmed SG, Stemmer-Rachamimov A, Brenner GJ, Stankovic KM. NLRP3 inflammasome activation in human vestibular schwannoma: Implications for tumor-induced hearing loss. Hearing Research. 381: 107770. PMID 31430634 DOI: 10.1016/J.Heares.2019.07.007  0.443
2019 Neftel C, Laffy J, Filbin MG, Hara T, Shore ME, Rahme GJ, Richman AR, Silverbush D, Shaw ML, Hebert CM, Dewitt J, Gritsch S, Perez EM, Gonzalez Castro LN, Lan X, ... ... Stemmer-Rachamimov A, et al. An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma. Cell. PMID 31327527 DOI: 10.1016/J.Cell.2019.06.024  0.702
2019 Coy S, Rashid R, Stemmer-Rachamimov A, Santagata S. An update on the CNS manifestations of neurofibromatosis type 2. Acta Neuropathologica. PMID 31161239 DOI: 10.1007/S00401-019-02029-5  0.439
2019 Ahmed SG, Ahmed A, Maguire CA, Doha M, Sagers J, Lewis RM, Muzikansky A, Giovannini M, Stemmer-Rachamimov A, Stankovic KM, Fulci G, Brenner GJ. Gene therapy with apoptosis-associated speck-like protein (ASC), a newly described schwannoma tumor suppressor, inhibits schwannoma growth in vivo. Neuro-Oncology. PMID 30977509 DOI: 10.1093/Neuonc/Noz065  0.389
2019 Osum S, Stemmer-Rachamimov A, Widemann B, Dombi E, Vitte J, Dahiya S, Rizvi T, Ratner N, Messiaen L, Gutmann D, Giovannini M, Moertel C, Largaespada D, Watson A. TMOD-23. PRECLINICAL DRUG EVALUATION IN A GENETICALLY ENGINEERED MINIPIG MODEL OF NEUROFIBROMATOSIS TYPE 1 Neuro-Oncology. 21: vi267-vi267. DOI: 10.1093/Neuonc/Noz175.1122  0.393
2019 Seano G, Griveau A, Shelton S, Krishnan S, Wang N, Kloepper J, Huillard E, Batchelor T, Stemmer-Rachamimov A, Aghi M, Jain R, Rowitch D. OS12.4 In vivo dynamics and targeting of vessel co-option in glioma Neuro-Oncology. 21: iii23-iii23. DOI: 10.1093/Neuonc/Noz126.076  0.383
2018 Sade-Feldman M, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG, Jenkins RW, Lieb DJ, Chen JH, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A, Hoover PJ, Villani AC, Ivanova E, ... ... Stemmer-Rachamimov A, et al. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 175: 998-1013.e20. PMID 30388456 DOI: 10.1016/J.Cell.2018.10.038  0.383
2018 Gehlhausen JR, Hawley E, Wahle BM, He Y, Edwards D, Rhodes SD, Lajiness JD, Staser K, Chen S, Yang X, Yuan J, Li X, Jiang L, Smith A, Bessler W, ... ... Stemmer-Rachamimov A, et al. A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas. Human Molecular Genetics. PMID 30335132 DOI: 10.1093/Hmg/Ddy361  0.402
2018 Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, ... ... Stemmer-Rachamimov AO, et al. DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome. Acta Neuropathologica. PMID 30123936 DOI: 10.1007/S00401-018-1899-7  0.561
2018 Ortonne N, Wolkenstein P, Blakeley JO, Korf B, Plotkin SR, Riccardi VM, Miller DC, Huson S, Peltonen J, Rosenberg A, Carroll SL, Verma SK, Mautner V, Upadhyaya M, Stemmer-Rachamimov A. Cutaneous neurofibromas: Current clinical and pathologic issues. Neurology. 91: S5-S13. PMID 29987130 DOI: 10.1212/Wnl.0000000000005792  0.468
2018 Angus SP, Oblinger JL, Stuhlmiller TJ, DeSouza PA, Beauchamp RL, Witt L, Chen X, Jordan JT, Gilbert TSK, Stemmer-Rachamimov A, Gusella JF, Plotkin SR, Haggarty SJ, Chang LS, Johnson GL, et al. EPH receptor signaling as a novel therapeutic target in NF2-deficient meningioma. Neuro-Oncology. PMID 29982664 DOI: 10.1093/Neuonc/Noy046  0.467
2018 Allaway R, Angus SP, Beauchamp RL, Blakeley JO, Bott M, Burns SS, Carlstedt A, Chang LS, Chen X, Clapp DW, Desouza PA, Erdin S, Fernandez-Valle C, Guinney J, ... ... Stemmer-Rachamimov A, et al. Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2. Plos One. 13: e0197350. PMID 29897904 DOI: 10.1371/Journal.Pone.0197350  0.41
2018 Carrió M, Gel B, Terribas E, Zucchiatti AC, Moliné T, Rosas I, Teulé Á, Ramón Y Cajal S, López-Gutiérrez JC, Blanco I, Castellanos E, Lázaro C, Stemmer-Rachamimov A, Romagosa C, Serra E. Analysis of intra-tumor heterogeneity in Neurofibromatosis Type 1 plexiform neurofibromas and neurofibromas with atypical features: Correlating histological and genomic findings. Human Mutation. PMID 29774626 DOI: 10.1002/humu.23552  0.373
2018 Volak A, LeRoy SG, Natasan JS, Park DJ, Cheah PS, Maus A, Fitzpatrick Z, Hudry E, Pinkham K, Gandhi S, Hyman BT, Mu D, GuhaSarkar D, Stemmer-Rachamimov AO, Sena-Esteves M, et al. Virus vector-mediated genetic modification of brain tumor stromal cells after intravenous delivery. Journal of Neuro-Oncology. PMID 29767307 DOI: 10.1007/S11060-018-2889-2  0.485
2018 Griveau A, Seano G, Shelton SJ, Kupp R, Jahangiri A, Obernier K, Krishnan S, Lindberg OR, Yuen TJ, Tien AC, Sabo JK, Wang N, Chen I, Kloepper J, Larrouquere L, ... ... Stemmer-Rachamimov A, et al. A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment. Cancer Cell. PMID 29681511 DOI: 10.1016/J.Ccell.2018.03.020  0.381
2018 Zhao Y, Liu P, Zhang N, Chen J, Landegger LD, Wu L, Zhao F, Zhao Y, Zhang Y, Zhang J, Fujita T, Stemmer-Rachamimov A, Ferraro GB, Liu H, Muzikansky A, et al. Targeting the cMET pathway augments radiation response without adverse effect on hearing in NF2 schwannoma models. Proceedings of the National Academy of Sciences of the United States of America. PMID 29440379 DOI: 10.1073/Pnas.1719966115  0.401
2018 Wu LMN, Deng Y, Wang J, Zhao C, Wang J, Rao R, Xu L, Zhou W, Choi K, Rizvi TA, Remke M, Rubin JB, Johnson RL, Carroll TJ, Stemmer-Rachamimov AO, et al. Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell. 33: 292-308.e7. PMID 29438698 DOI: 10.1016/J.Ccell.2018.01.005  0.436
2018 Larque AB, Kradin RL, Chebib I, Nielsen GP, Selig MK, Thiele EA, Stemmer-Rachamimov A, Bredella MA, Kurzawa P, Deshpande V. Fibroma-like PEComa: A Tuberous Sclerosis Complex-related Lesion. The American Journal of Surgical Pathology. PMID 29324470 DOI: 10.1097/Pas.0000000000001024  0.428
2018 Ligon K, Lupo J, Molinaro A, Block S, Charbonneau S, Geduldig J, Stemmer-Rachamimov A, DeAngelis L, Yong W, Schultz N, Young R, Huang R, Chang S, Arrillaga-Romany I, Alexander B, et al. PATH-08. THE IVY GLIOBLASTOMA PATIENT ATLAS - A NOVEL CLINICAL AND RADIO-GENOMICS RESOURCE FOR EARLY PHASE CLINICAL TRIAL DESIGN AND INTERPRETATION Neuro-Oncology. 20: vi159-vi159. DOI: 10.1093/Neuonc/Noy148.664  0.498
2017 Zimering JH, Choi BD, Koch MJ, Dewitt JC, Stemmer-Rachamimov A, Shin JH. Sporadic NF2 Mosaic: Multiple spinal schwannomas presenting with severe, intractable pain following pregnancy. Interdisciplinary Neurosurgery : Advanced Techniques and Case Management. 10: 142-145. PMID 29780700 DOI: 10.1016/J.Inat.2017.09.006  0.306
2017 Jenkins RW, Aref AR, Lizotte PH, Ivanova E, Stinson S, Zhou CW, Bowden M, Deng J, Liu H, Miao D, He MX, Walker W, Zhang G, Tian T, Cheng C, ... ... Stemmer-Rachamimov AO, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discovery. PMID 29101162 DOI: 10.1158/2159-8290.Cd-17-0833  0.4
2017 Sade-Feldman M, Jiao YJ, Chen JH, Rooney MS, Barzily-Rokni M, Eliane JP, Bjorgaard SL, Hammond MR, Vitzthum H, Blackmon SM, Frederick DT, Hazar-Rethinam M, Nadres BA, Van Seventer EE, Shukla SA, ... ... Stemmer-Rachamimov A, et al. Resistance to checkpoint blockade therapy through inactivation of antigen presentation. Nature Communications. 8: 1136. PMID 29070816 DOI: 10.1038/S41467-017-01062-W  0.342
2017 Zhang N, Chen J, Ferraro G, Wu L, Datta M, Jain RK, Plotkin SR, Stemmer-Rachamimov A, Xu L. Anti-VEGF treatment improves neurological function in tumors of the nervous system. Experimental Neurology. PMID 28911884 DOI: 10.1016/J.Expneurol.2017.09.008  0.37
2017 Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y, Chevalier A, Ducar M, Thorner AR, van Hummelen P, Stemmer-Rachamimov A, et al. Genomic landscape of high-grade meningiomas. Npj Genomic Medicine. 2. PMID 28713588 DOI: 10.1038/S41525-017-0014-7  0.437
2017 Kim D, Niemierko A, Hwang WL, Stemmer-Rachamimov AO, Curry WT, Barker FG, Martuza RL, Oh KS, Loeffler JS, Shih HA. Histopathological prognostic factors of recurrence following definitive therapy for atypical and malignant meningiomas. Journal of Neurosurgery. 1-10. PMID 28621619 DOI: 10.3171/2016.11.Jns16913  0.388
2017 Miettinen MM, Antonescu CR, Fletcher CDM, Kim A, Lazar AJ, Quezado MM, Reilly KM, Stemmer-Rachamimov A, Stewart DR, Viskochil D, Widemann B, Perry A. Histopathologic Evaluation of Atypical Neurofibromatous Tumors and Their Transformation into Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis 1 Patients - A Consensus Overview. Human Pathology. PMID 28551330 DOI: 10.1016/J.Humpath.2017.05.010  0.457
2017 Blakeley JO, Bakker A, Barker A, Clapp W, Ferner R, Fisher MJ, Giovannini M, Gutmann DH, Karajannis MA, Kissil JL, Legius E, Lloyd AC, Packer RJ, Ramesh V, Riccardi VM, ... ... Stemmer-Rachamimov A, et al. The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. PMID 28436162 DOI: 10.1002/Ajmg.A.38239  0.341
2017 Okazaki A, Gameiro PA, Christodoulou D, Laviollette L, Schneider M, Chaves F, Stemmer-Rachamimov A, Yazinski SA, Lee R, Stephanopoulos G, Zou L, Iliopoulos O. Glutaminase and poly(ADP-ribose) polymerase inhibitors suppress pyrimidine synthesis and VHL-deficient renal cancers. The Journal of Clinical Investigation. PMID 28346230 DOI: 10.1172/Jci87800  0.323
2016 Ostrow KL, Bergner AL, Blakeley J, Evans DG, Ferner R, Friedman JM, Harris GJ, Jordan JT, Korf B, Langmead S, Leschziner G, Mautner V, Merker VL, Papi L, Plotkin SR, ... ... Stemmer-Rachamimov A, et al. Creation of an international registry to support discovery in schwannomatosis. American Journal of Medical Genetics. Part A. PMID 27759912 DOI: 10.1002/Ajmg.A.38024  0.361
2016 Guerrant W, Kota S, Troutman S, Mandati V, Fallahi M, Stemmer-Rachamimov A, Kissil JL. YAP mediates tumorigenesis in neurofibromatosis type 2 by promoting cell survival and proliferation through a COX2-EGFR signaling axis. Cancer Research. PMID 27216189 DOI: 10.1158/0008-5472.Can-15-1144  0.372
2016 Lu F, Chen Y, Zhao C, Wang H, He D, Xu L, Wang J, He X, Deng Y, Lu EE, Liu X, Verma R, Bu H, Drissi R, Fouladi M, ... Stemmer-Rachamimov AO, et al. Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma. Cancer Cell. 29: 669-83. PMID 27165742 DOI: 10.1016/J.Ccell.2016.03.027  0.428
2016 Nigim F, Esaki SI, Hood M, Lelic N, James MF, Ramesh V, Stemmer-Rachamimov A, Cahill DP, Brastianos PK, Rabkin SD, Martuza RL, Wakimoto H. A new patient-derived orthotopic malignant meningioma model treated with oncolytic herpes simplex virus. Neuro-Oncology. PMID 26951380 DOI: 10.1093/Neuonc/Now031  0.478
2015 Flavahan WA, Drier Y, Liau BB, Gillespie SM, Venteicher AS, Stemmer-Rachamimov AO, Suvà ML, Bernstein BE. Insulator dysfunction and oncogene activation in IDH mutant gliomas. Nature. PMID 26700815 DOI: 10.1038/Nature16490  0.319
2015 Gao X, Zhao Y, Stemmer-Rachamimov AO, Liu H, Huang P, Chin S, Selig MK, Plotkin SR, Jain RK, Xu L. Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model. Proceedings of the National Academy of Sciences of the United States of America. PMID 26554010 DOI: 10.1073/Pnas.1512570112  0.355
2015 van der Vos KE, Abels ER, Zhang X, Lai C, Carrizosa E, Oakley D, Prabhakar S, Mardini O, Crommentuijn MH, Skog J, Krichevsky AM, Stemmer-Rachamimov A, Mempel TR, El Khoury J, Hickman SE, et al. Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain. Neuro-Oncology. PMID 26433199 DOI: 10.1093/Neuonc/Nov244  0.666
2015 Brastianos PK, Carter SL, Santagata S, Cahill DP, Taylor-Weiner A, Jones RT, Van Allen EM, Lawrence MS, Horowitz PM, Cibulskis K, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Curry WT, ... ... Stemmer-Rachamimov A, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discovery. PMID 26410082 DOI: 10.1158/2159-8290.Cd-15-0369  0.697
2015 Marciscano AE, Stemmer-Rachamimov AO, Niemierko A, Larvie M, Curry WT, Barker FG, Martuza RL, McGuone D, Oh KS, Loeffler JS, Shih HA. Benign meningiomas (WHO Grade I) with atypical histological features: correlation of histopathological features with clinical outcomes. Journal of Neurosurgery. 1-9. PMID 26274991 DOI: 10.3171/2015.1.Jns142228  0.326
2015 Beauchamp RL, James MF, DeSouza PA, Wagh V, Zhao WN, Jordan JT, Stemmer-Rachamimov A, Plotkin SR, Gusella JF, Haggarty SJ, Ramesh V. A high-throughput kinome screen reveals serum/glucocorticoid-regulated kinase 1 as a therapeutic target for NF2-deficient meningiomas. Oncotarget. 6: 16981-97. PMID 26219339 DOI: 10.18632/Oncotarget.4858  0.39
2015 Shankar GM, Francis JM, Rinne ML, Ramkissoon SH, Huang FW, Venteicher AS, Akama-Garren EH, Kang YJ, Lelic N, Kim JC, Brown LE, Charbonneau SK, Golby AJ, Sekhar Pedamallu C, Hoang MP, ... ... Stemmer-Rachamimov A, et al. Rapid Intraoperative Molecular Characterization of Glioma. Jama Oncology. PMID 26181761 DOI: 10.1001/Jamaoncol.2015.0917  0.672
2015 Stivaros SM, Stemmer-Rachamimov AO, Alston R, Plotkin SR, Nadol JB, Quesnel A, O'Malley J, Whitfield GA, McCabe MG, Freeman SR, Lloyd SK, Wright NB, Kilday JP, Kamaly-Asl ID, Mills SJ, et al. Multiple synchronous sites of origin of vestibular schwannomas in neurofibromatosis Type 2. Journal of Medical Genetics. PMID 26104281 DOI: 10.1136/Jmedgenet-2015-103050  0.512
2015 Prabhakar S, Zhang X, Goto J, Han S, Lai C, Bronson R, Sena-Esteves M, Ramesh V, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO. Survival benefit and phenotypic improvement by hamartin gene therapy in a tuberous sclerosis mouse brain model. Neurobiology of Disease. 82: 22-31. PMID 26019056 DOI: 10.1016/J.Nbd.2015.04.018  0.301
2015 Redjal N, Agarwalla PK, Dietrich J, Dinevski N, Stemmer-Rachamimov A, Nahed BV, Loeffler JS. Remote acute demyelination after focal proton radiation therapy for optic nerve meningioma Journal of Clinical Neuroscience. 22: 1367-1369. PMID 25937571 DOI: 10.1016/J.Jocn.2015.02.017  0.377
2015 Taylor JW, Dietrich J, Gerstner ER, Norden AD, Rinne ML, Cahill DP, Stemmer-Rachamimov A, Wen PY, Betensky RA, Giorgio DH, Snodgrass K, Randall AE, Batchelor TT, Chi AS. Phase 2 study of bosutinib, a Src inhibitor, in adults with recurrent glioblastoma. Journal of Neuro-Oncology. 121: 557-63. PMID 25411098 DOI: 10.1007/S11060-014-1667-Z  0.541
2015 Gehlhausen JR, Park SJ, Hickox AE, Shew M, Staser K, Rhodes SD, Menon K, Lajiness JD, Mwanthi M, Yang X, Yuan J, Territo P, Hutchins G, Nalepa G, Yang FC, ... ... Stemmer-Rachamimov A, et al. A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation. Human Molecular Genetics. 24: 1-8. PMID 25113746 DOI: 10.1093/Hmg/Ddu414  0.439
2015 Metelo AM, Kamburov A, Kim J, Lockerman E, Lee D, Barker F, Engelman J, Stemmer-Rachamimov A, Getz G, Iliopoulos O. Abstract A13: Functional genomic analysis of central nervous system hemangioblastomas Brain. 75. DOI: 10.1158/1538-7445.Brain15-A13  0.467
2015 Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Allen EV, Ligon KL, Tabernero J, Seoane J, Martinez-Saez E, Cahill D, Curry WT, Dunn IF, Paek SH, Hummelen PV, ... ... Stemmer-Rachamimov A, et al. Abstract 4727: Genomic characterization of brain metastases reveals divergent evolution and metastasis specific mutations Brain. 75: 4727-4727. DOI: 10.1158/1538-7445.Am2015-4727  0.694
2015 Vitte J, Chareyre F, Stemmer-Rachamimov A, Judkins A, Giovannini M. PM-02 * CONDITIONAL INACTIVATION OF SMARCB1 IN P0 PERMISSIVE MOUSE CELLS GENERATES RHABDOID TUMORS IN THE PERIPHERAL NERVOUS SYSTEM AND IN THE BRAIN Neuro-Oncology. 17: iii31-iii31. DOI: 10.1093/Neuonc/Nov061.125  0.502
2015 Prabhakar S, Zhang X, Goto J, Sena-Esteves M, Ramesh V, Bronson R, Chen JW, Stemmer-Rachamimov AO, Kwiatkowski DJ, Breakefield XO. 196. AAV-Mediated Gene Replacement Therapy in Mouse Model of Tuberous Sclerosis Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)33801-1  0.359
2015 Brastianos P, Carter S, Santagata S, Cahill D, Taylor-Weiner A, Jones R, Ligon K, Tabernero J, Seoane J, Martinez Saez E, Johnson B, Choueiri T, Stemmer-Rachamimov A, Lin N, Beroukhim R, et al. 2905 Genomic characterization of brain metastases and paired primary tumors reveals branched evolution and potential therapeutic targets European Journal of Cancer. 51: S586. DOI: 10.1016/S0959-8049(16)31622-7  0.652
2015 Hwang W, Marciscano AE, Kim D, Stemmer-Rachamimov AO, Curry WT, Barker FG, Larvie M, Shih HA. Correlation of Imaging Characteristics With Histopathological WHO Grade in Meningiomas International Journal of Radiation Oncology Biology Physics. 93. DOI: 10.1016/J.Ijrobp.2015.07.765  0.393
2014 Shankar GM, Taylor-Weiner A, Lelic N, Jones RT, Kim JC, Francis JM, Abedalthagafi M, Borges LF, Coumans JV, Curry WT, Nahed BV, Shin JH, Paek SH, Park SH, Stewart C, ... ... Stemmer-Rachamimov AO, et al. Sporadic hemangioblastomas are characterized by cryptic VHL inactivation. Acta Neuropathologica Communications. 2: 167. PMID 25589003 DOI: 10.1186/S40478-014-0167-X  0.715
2014 Plotkin SR, Albers AC, Babovic-Vuksanovic D, Blakeley JO, Breakefield XO, Dunn CM, Evans DG, Fisher MJ, Friedman JM, Giovannini M, Gutmann DH, Kalamarides M, McClatchey AI, Messiaen L, Morrison H, ... ... Stemmer-Rachamimov AO, et al. Update from the 2013 International Neurofibromatosis Conference. American Journal of Medical Genetics. Part A. 164: 2969-78. PMID 25255738 DOI: 10.1002/Ajmg.A.36754  0.391
2014 Pier DB, Nunes FP, Plotkin SR, Stemmer-Rachamimov AO, Kim JC, Shih HA, Brastianos P, Lin AE. Turner syndrome and meningioma: support for a possible increased risk of neoplasia in Turner syndrome. European Journal of Medical Genetics. 57: 269-74. PMID 24675142 DOI: 10.1016/J.Ejmg.2014.03.005  0.349
2014 Antoszczyk S, Spyra M, Mautner VF, Kurtz A, Stemmer-Rachamimov AO, Martuza RL, Rabkin SD. Treatment of orthotopic malignant peripheral nerve sheath tumors with oncolytic herpes simplex virus. Neuro-Oncology. 16: 1057-66. PMID 24470552 DOI: 10.1093/Neuonc/Not317  0.402
2014 Wu J, Patmore DM, Jousma E, Eaves DW, Breving K, Patel AV, Schwartz EB, Fuchs JR, Cripe TP, Stemmer-Rachamimov AO, Ratner N. EGFR-STAT3 signaling promotes formation of malignant peripheral nerve sheath tumors. Oncogene. 33: 173-80. PMID 23318430 DOI: 10.1038/Onc.2012.579  0.373
2014 Brastianos PK, Carter SL, Santagata S, Taylor-Weiner A, Jones RT, Horowitz PM, Ligon KL, Seaone J, Martinez-Saez E, Tabernero J, Cahill DP, Paek S, Dunn IF, Johnson BE, Choueiri TK, ... ... Stemmer-Rachamimov A, et al. Abstract NG03: Genomic characterization of 101 brain metastases and paired primary tumors reveals patterns of clonal evolution and selection of driver mutations Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ng03  0.455
2014 Ratner N, Keng V, Patmore DM, Kendall JK, Jousma E, Choi K, Fan D, Schwartz EB, Fuchs JR, Zou Y, Kim M, Dombi E, Levy DE, Cancelas JA, Stemmer-Rachamimov A, et al. PM-18 * EGFR-STAT3 ACTIVATES  -CATENIN SIGNALING TO DRIVE NEUROFIBROMA INITIATION IN NF1, AND PLAYS A ROLE IN TUMOR MAINTENANCE Neuro-Oncology. 16: v172-v173. DOI: 10.1093/Neuonc/Nou268.18  0.371
2014 Brastianos P, Carter S, Santagata S, Taylor-Weiner A, Jones R, Van Allen E, Horowitz P, Ligon K, Cahill D, Dunn I, Van Hummelen P, Lin N, Curry W, Stemmer-Rachamimov A, Beroukhim R, et al. BM-07 * GENOMIC CHARACTERIZATION OF BRAIN METASTASES REVEALS BRANCHED EVOLUTION AND METASTASIS-SPECIFIC MUTATIONS Neuro-Oncology. 16: v33-v33. DOI: 10.1093/Neuonc/Nou240.7  0.718
2014 Vitte J, Chareyre F, Stemmer-Rachamimov A, Judkins A, Giovannini M. Conditional Inactivation of SMARCB1 in P0 Permissive Mouse Cells Generates Rhabdoid Tumors in the Peripheral Nervous System Cancer Genetics. 207: 451. DOI: 10.1016/J.Cancergen.2014.09.023  0.423
2013 Mayes DA, Rizvi TA, Titus-Mitchell H, Oberst R, Ciraolo GM, Vorhees CV, Robinson AP, Miller SD, Cancelas JA, Stemmer-Rachamimov AO, Ratner N. Nf1 loss and Ras hyperactivation in oligodendrocytes induce NOS-driven defects in myelin and vasculature. Cell Reports. 4: 1197-212. PMID 24035394 DOI: 10.1016/J.Celrep.2013.08.011  0.317
2013 Yi C, Shen Z, Stemmer-Rachamimov A, Dawany N, Troutman S, Showe LC, Liu Q, Shimono A, Sudol M, Holmgren L, Stanger BZ, Kissil JL. The p130 isoform of angiomotin is required for Yap-mediated hepatic epithelial cell proliferation and tumorigenesis. Science Signaling. 6: ra77. PMID 24003254 DOI: 10.1126/Scisignal.2004060  0.326
2013 Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Davidson C, Huang Y, Riedemann L, Taylor J, Ivy P, Duda DG, Ancukiewicz M, Plotkin SR, Chi AS, Gerstner ER, Eichler AF, ... ... Stemmer-Rachamimov AO, et al. Increase in tumor-associated macrophages after antiangiogenic therapy is associated with poor survival among patients with recurrent glioblastoma. Neuro-Oncology. 15: 1079-87. PMID 23828240 DOI: 10.1093/Neuonc/Not082  0.618
2013 Prabhakar S, Goto J, Zhang X, Zuang X, Sena-Esteves M, Bronson R, Brockmann J, Gianni D, Wojtkiewicz GR, Chen JW, Stemmer-Rachamimov A, Kwiatkowski DJ, Breakefield XO. Stochastic model of Tsc1 lesions in mouse brain. Plos One. 8: e64224. PMID 23696872 DOI: 10.1371/Journal.Pone.0064224  0.37
2013 Las Heras F, Martuza R, Caruso P, Rincon S, Stemmer-Rachamimov A. 24-Year-old woman with an internal auditory canal mass Brain Pathology. 23: 361-362. PMID 23587143 DOI: 10.1111/Bpa.12055  0.436
2013 Nunes FP, Merker VL, Jennings D, Caruso PA, di Tomaso E, Muzikansky A, Barker FG, Stemmer-Rachamimov A, Plotkin SR. Bevacizumab treatment for meningiomas in NF2: a retrospective analysis of 15 patients. Plos One. 8: e59941. PMID 23555840 DOI: 10.1371/Journal.Pone.0059941  0.453
2013 Plotkin SR, Blakeley JO, Evans DG, Hanemann CO, Hulsebos TJ, Hunter-Schaedle K, Kalpana GV, Korf B, Messiaen L, Papi L, Ratner N, Sherman LS, Smith MJ, Stemmer-Rachamimov AO, Vitte J, et al. Update from the 2011 International Schwannomatosis Workshop: From genetics to diagnostic criteria. American Journal of Medical Genetics. Part A. 161: 405-16. PMID 23401320 DOI: 10.1002/Ajmg.A.35760  0.46
2013 Peyre M, Clermont-Taranchon E, Stemmer-Rachamimov A, Kalamarides M. Miniaturized handheld confocal microscopy identifies focal brain invasion in a mouse model of aggressive meningioma Brain Pathology. 23: 371-377. PMID 23356716 DOI: 10.1111/Bpa.12039  0.381
2013 Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD, Raza A, Sunkavalli A, Macconaill LE, Stemmer-Rachamimov AO, Louis DN, et al. Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nature Genetics. 45: 285-9. PMID 23334667 DOI: 10.1038/Ng.2526  0.7
2013 Prabhakar S, Taherian M, Gianni D, Conlon TJ, Fulci G, Brockmann J, Stemmer-Rachamimov A, Sena-Esteves M, Breakefield XO, Brenner GJ. Regression of schwannomas induced by adeno-associated virus-mediated delivery of caspase-1. Human Gene Therapy. 24: 152-62. PMID 23140466 DOI: 10.1089/Hum.2012.094  0.444
2013 Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C, Volk A, Niwa-Kawakita M, Karboul N, Giovannini M, Kalamarides M. Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation Oncogene. 32: 4264-4272. PMID 23045274 DOI: 10.1038/Onc.2012.436  0.446
2013 Lu-Emerson C, Snuderl M, Kirkpatrick ND, Goveia J, Taylor J, Davidson C, Huang Y, Riedemann L, Ivy SP, Duda GD, Ancukiewicz M, Plotkin SR, Chi A, Gerstner ER, Eichler AF, ... ... Stemmer-Rachamimov AO, et al. Abstract LB-339: Increase in tumor-associated macrophages (TAMs) after antiangiogenic therapy is associated with poor survival in recurrent glioblastoma (GBM) patients. Cancer Research. 73. DOI: 10.1158/1538-7445.Am2013-Lb-339  0.422
2013 Brastianos P, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon K, Hummelen PV, Ducar M, Raza A, Sunkavalli A, MacConaill L, Stemmer-Rachamimov A, Louis DN, Hahn WC, et al. Abstract 803: Genomic sequencing of meningiomas reveals oncogenic SMO and AKT1 mutations. Cancer Research. 73: 803-803. DOI: 10.1158/1538-7445.Am2013-803  0.692
2012 Smith MJ, Walker JA, Shen Y, Stemmer-Rachamimov A, Gusella JF, Plotkin SR. Expression of SMARCB1 (INI1) mutations in familial schwannomatosis. Human Molecular Genetics. 21: 5239-45. PMID 22949514 DOI: 10.1093/Hmg/Dds370  0.422
2012 Merker VL, Esparza S, Smith MJ, Stemmer-Rachamimov A, Plotkin SR. Clinical features of schwannomatosis: a retrospective analysis of 87 patients. The Oncologist. 17: 1317-22. PMID 22927469 DOI: 10.1634/Theoncologist.2012-0162  0.421
2012 Huynh N, Stemmer-Rachamimov AO, Swearingen B, Cestari DM. Decreased vision and junctional scotoma from pituicytoma. Case Reports in Ophthalmology. 3: 190-6. PMID 22740829 DOI: 10.1159/000339242  0.45
2012 James MF, Stivison E, Beauchamp R, Han S, Li H, Wallace MR, Gusella JF, Stemmer-Rachamimov AO, Ramesh V. Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types. Molecular Cancer Research : McR. 10: 649-59. PMID 22426462 DOI: 10.1158/1541-7786.Mcr-11-0425-T  0.424
2012 Hagel C, Stemmer-Rachamimov AO, Bornemann A, Schuhmann M, Nagel C, Huson S, Evans DG, Plotkin S, Matthies C, Kluwe L, Mautner VF. Clinical presentation, immunohistochemistry and electron microscopy indicate neurofibromatosis type 2-associated gliomas to be spinal ependymomas. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 32: 611-6. PMID 22394059 DOI: 10.1111/J.1440-1789.2012.01306.X  0.398
2012 Babovic-Vuksanovic D, Messiaen L, Nagel C, Brems H, Scheithauer B, Denayer E, Mao R, Sciot R, Janowski KM, Schuhmann MU, Claes K, Beert E, Garrity JA, Spinner RJ, Stemmer-Rachamimov A, et al. Multiple orbital neurofibromas, painful peripheral nerve tumors, distinctive face and marfanoid habitus: a new syndrome. European Journal of Human Genetics : Ejhg. 20: 618-25. PMID 22258529 DOI: 10.1038/Ejhg.2011.275  0.413
2012 Fleming AJ, Hukin J, Rassekh R, Fryer C, Kim J, Stemmer-Rachamimov A, Birks DK, Huang A, Yip S, Dunham C. Atypical teratoid rhabdoid tumors (ATRTs): the British Columbia's Children's Hospital's experience, 1986-2006. Brain Pathology (Zurich, Switzerland). 22: 625-35. PMID 22188464 DOI: 10.1111/J.1750-3639.2011.00561.X  0.58
2012 Blakeley JO, Evans DG, Adler J, Brackmann D, Chen R, Ferner RE, Hanemann CO, Harris G, Huson SM, Jacob A, Kalamarides M, Karajannis MA, Korf BR, Mautner VF, McClatchey AI, ... ... Stemmer-Rachamimov AO, et al. Consensus recommendations for current treatments and accelerating clinical trials for patients with neurofibromatosis type 2. American Journal of Medical Genetics. Part A. 158: 24-41. PMID 22140088 DOI: 10.1002/Ajmg.A.34359  0.433
2012 Kalamarides M, Acosta MT, Babovic-Vuksanovic D, Carpen O, Cichowski K, Evans DG, Giancotti F, Hanemann CO, Ingram D, Lloyd AC, Mayes DA, Messiaen L, Morrison H, North K, Packer R, ... ... Stemmer-Rachamimov A, et al. Neurofibromatosis 2011: a report of the Children's Tumor Foundation annual meeting. Acta Neuropathologica. 123: 369-80. PMID 22083253 DOI: 10.1007/S00401-011-0905-0  0.4
2012 Wakimoto H, Mohapatra G, Kanai R, Curry WT, Yip S, Nitta M, Patel AP, Barnard ZR, Stemmer-Rachamimov AO, Louis DN, Martuza RL, Rabkin SD. Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells. Neuro-Oncology. 14: 132-44. PMID 22067563 DOI: 10.1093/Neuonc/Nor195  0.747
2012 Zhang W, Fulci G, Buhrman JS, Stemmer-Rachamimov AO, Chen JW, Wojtkiewicz GR, Weissleder R, Rabkin SD, Martuza RL. Bevacizumab with angiostatin-armed oHSV increases antiangiogenesis and decreases bevacizumab-induced invasion in U87 glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 37-45. PMID 21915104 DOI: 10.1038/Mt.2011.187  0.4
2012 Merker V, Esparza S, Smith M, Stemmer-Rachamimov A, Plotkin S. Clinical Features of the Schwannomatosis Tumor Suppressor Syndrome: A Retrospective Analysis of 87 Patients (S45.003) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.S45.003  0.396
2012 Ly I, Pine A, Stemmer-Rachamimov A, Hochberg F, Dietrich J. Clinical, Histopathologic, and Magnetic Resonance Imaging (MRI) Findings in Gliomatosis Cerebri (P03.139) Neurology. 78. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P03.139  0.366
2012 Lu-Emerson C, Snuderl M, Davidson C, Kirkpatrick ND, Huang Y, Duda DG, Ancukiewicz M, Stemmer-Rachamimov A, Batchelor T, Jain RK. Effect of antiangiogenic therapy on tumor-associated macrophages in recurrent glioblastoma. Journal of Clinical Oncology. 30: 2010-2010. DOI: 10.1200/Jco.2012.30.15_Suppl.2010  0.582
2012 Wu J, Keng V, Patmore DM, Jousma E, Eaves DW, Johansson G, Schwartz EB, Fuchs JR, Dunn S, Lindquist D, Dombi E, Widemann BC, Stemmer-Rachamimov Ao, Cancelas JA, Cripe TP, et al. Abstract 2937: An EGFR-STAT3 pathway promotes NF1 peripheral nerve tumorigenesis and transformation Cancer Research. 72: 2937-2937. DOI: 10.1158/1538-7445.Am2012-2937  0.362
2011 Kleijn A, Chen JW, Buhrman JS, Wojtkiewicz GR, Iwamoto Y, Lamfers ML, Stemmer-Rachamimov AO, Rabkin SD, Weissleder R, Martuza RL, Fulci G. Distinguishing inflammation from tumor and peritumoral edema by myeloperoxidase magnetic resonance imaging. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 4484-93. PMID 21558403 DOI: 10.1158/1078-0432.Ccr-11-0575  0.419
2011 Mayes DA, Rizvi TA, Cancelas JA, Kolasinski NT, Ciraolo GM, Stemmer-Rachamimov AO, Ratner N. Perinatal or adult Nf1 inactivation using tamoxifen-inducible PlpCre each cause neurofibroma formation. Cancer Research. 71: 4675-85. PMID 21551249 DOI: 10.1158/0008-5472.Can-10-4558  0.431
2011 Gallagher A, Kovach A, Stemmer-Rachamimov A, Rosenberg AE, Eskandar E, Thiele EA. Metaplastic bone in a cortical tuber of a young patient with tuberous sclerosis complex. Neurology. 76: 1602-4. PMID 21536642 DOI: 10.1212/Wnl.0B013E3182190D25  0.337
2011 Yi C, Troutman S, Fera D, Stemmer-Rachamimov A, Avila JL, Christian N, Persson NL, Shimono A, Speicher DW, Marmorstein R, Holmgren L, Kissil JL. A tight junction-associated Merlin-angiomotin complex mediates Merlin's regulation of mitogenic signaling and tumor suppressive functions. Cancer Cell. 19: 527-40. PMID 21481793 DOI: 10.1016/J.Ccr.2011.02.017  0.353
2011 Kalamarides M, Stemmer-Rachamimov AO, Niwa-Kawakita M, Chareyre F, Taranchon E, Han ZY, Martinelli C, Lusis EA, Hegedus B, Gutmann DH, Giovannini M. Identification of a progenitor cell of origin capable of generating diverse meningioma histological subtypes. Oncogene. 30: 2333-44. PMID 21242963 DOI: 10.1038/Onc.2010.609  0.382
2011 Rodriguez FJ, Scheithauer BW, George D, Midha R, MacCollin M, Stemmer-Rachamimov AO. Superficial neurofibromas in the setting of schwannomatosis: nosologic implications. Acta Neuropathologica. 121: 663-8. PMID 21191601 DOI: 10.1007/S00401-010-0793-8  0.334
2011 Saydam O, Senol O, Würdinger T, Mizrak A, Ozdener GB, Stemmer-Rachamimov AO, Yi M, Stephens RM, Krichevsky AM, Saydam N, Brenner GJ, Breakefield XO. miRNA-7 attenuation in Schwannoma tumors stimulates growth by upregulating three oncogenic signaling pathways. Cancer Research. 71: 852-61. PMID 21156648 DOI: 10.1158/0008-5472.Can-10-1219  0.329
2011 Saydam O, Ozdener GB, Senol O, Mizrak A, Prabhakar S, Stemmer-Rachamimov AO, Breakefield XO, Brenner GJ. A novel imaging-compatible sciatic nerve schwannoma model. Journal of Neuroscience Methods. 195: 75-7. PMID 21111000 DOI: 10.1016/J.Jneumeth.2010.10.021  0.42
2011 Prithviraj GK, Sommers SR, Jump RL, Halmos B, Chambless LB, Parker SL, Hassam-Malani L, McGirt MJ, Thompson RC, Chambless LB, Parker SL, Hassam-Malani L, McGirt MJ, Thompson RC, Hunter K, ... ... Stemmer-Rachamimov A, ... ... Stemmer-Rachamimov A, et al. MEDICAL AND NEURO-ONCOLOGY Neuro-Oncology. 13: iii41-iii68. DOI: 10.1093/Neuonc/Nor152  0.484
2010 Saydam O, Senol O, Schaaij-Visser TB, Pham TV, Piersma SR, Stemmer-Rachamimov AO, Wurdinger T, Peerdeman SM, Jimenez CR. Comparative protein profiling reveals minichromosome maintenance (MCM) proteins as novel potential tumor markers for meningiomas. Journal of Proteome Research. 9: 485-94. PMID 19877719 DOI: 10.1021/Pr900834H  0.389
2010 Prabhakar S, Brenner GJ, Sung B, Messerli SM, Mao J, Sena-Esteves M, Stemmer-Rachamimov A, Tannous B, Breakefield XO. Imaging and therapy of experimental schwannomas using HSV amplicon vector-encoding apoptotic protein under Schwann cell promoter. Cancer Gene Therapy. 17: 266-74. PMID 19834516 DOI: 10.1038/Cgt.2009.71  0.368
2010 Doucette TA, Kong L, Yang Y, Wei J, Wang J, Fuller GN, Heimberger AB, Rao G, Ajewung N, Kamnasaran D, Katz AM, Amankulor N, Squatrito M, Hambardzumyan D, Holland EC, ... ... Stemmer-Rachamimov AO, et al. Tumor Models (In Vivo/In Vitro) Neuro-Oncology. 12: iv130-iv136. DOI: 10.1093/Neuonc/Noq116.S20  0.554
2009 Shen Y, Nunes F, Stemmer-Rachamimov A, James M, Mohapatra G, Plotkin S, Betensky RA, Engler DA, Roy J, Ramesh V, Gusella JF. Genomic profiling distinguishes familial multiple and sporadic multiple meningiomas. Bmc Medical Genomics. 2: 42. PMID 19589153 DOI: 10.1186/1755-8794-2-42  0.435
2009 Plotkin SR, Stemmer-Rachamimov AO, Barker FG, Halpin C, Padera TP, Tyrrell A, Sorensen AG, Jain RK, di Tomaso E. Hearing improvement after bevacizumab in patients with neurofibromatosis type 2. The New England Journal of Medicine. 361: 358-67. PMID 19587327 DOI: 10.1056/Nejmoa0902579  0.401
2009 McGillicuddy LT, Fromm JA, Hollstein PE, Kubek S, Beroukhim R, De Raedt T, Johnson BW, Williams SM, Nghiemphu P, Liau LM, Cloughesy TF, Mischel PS, Parret A, Seiler J, Moldenhauer G, ... ... Stemmer-Rachamimov AO, et al. Proteasomal and genetic inactivation of the NF1 tumor suppressor in gliomagenesis. Cancer Cell. 16: 44-54. PMID 19573811 DOI: 10.1016/J.Ccr.2009.05.009  0.433
2009 Stankovic KM, Mrugala MM, Martuza RL, Silver M, Betensky RA, Nadol JB, Stemmer-Rachamimov AO. Genetic determinants of hearing loss associated with vestibular schwannomas. Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology. 30: 661-7. PMID 19546833 DOI: 10.1097/Mao.0B013E3181A66Ece  0.374
2009 James MF, Han S, Polizzano C, Plotkin SR, Manning BD, Stemmer-Rachamimov AO, Gusella JF, Ramesh V. NF2/merlin is a novel negative regulator of mTOR complex 1, and activation of mTORC1 is associated with meningioma and schwannoma growth. Molecular and Cellular Biology. 29: 4250-61. PMID 19451225 DOI: 10.1128/Mcb.01581-08  0.444
2009 Wakimoto H, Kesari S, Farrell CJ, Curry WT, Zaupa C, Aghi M, Kuroda T, Stemmer-Rachamimov A, Shah K, Liu TC, Jeyaretna DS, Debasitis J, Pruszak J, Martuza RL, Rabkin SD. Human glioblastoma-derived cancer stem cells: establishment of invasive glioma models and treatment with oncolytic herpes simplex virus vectors. Cancer Research. 69: 3472-81. PMID 19351838 DOI: 10.1158/0008-5472.Can-08-3886  0.408
2009 Scheithauer BW, Swearingen B, Whyte ET, Auluck PK, Stemmer-Rachamimov AO. Ependymoma of the sella turcica: a variant of pituicytoma. Human Pathology. 40: 435-40. PMID 18992914 DOI: 10.1016/J.Humpath.2008.08.013  0.733
2009 Chang Z, Guo CL, Ahronowitz I, Stemmer-Rachamimov AO, MacCollin M, Nunes FP. A role for the p53 pathway in the pathology of meningiomas with NF2 loss. Journal of Neuro-Oncology. 91: 265-70. PMID 18974932 DOI: 10.1007/S11060-008-9721-3  0.434
2008 Smith ER, Loeffler J, Misra M, Pomerantz SR, Stemmer-Rachamimov A, Post MD. Case records of the Massachusetts General Hospital. Case 37-2008. A 17-year-old boy with a pituitary tumor and skull abnormalities. The New England Journal of Medicine. 359: 2367-77. PMID 19038883 DOI: 10.1056/Nejmcpc0806983  0.323
2008 Jones GN, Tep C, Towns WH, Mihai G, Tonks ID, Kay GF, Schmalbrock PM, Stemmer-Rachamimov AO, Yoon SO, Kirschner LS. Tissue-specific ablation of Prkar1a causes schwannomas by suppressing neurofibromatosis protein production. Neoplasia (New York, N.Y.). 10: 1213-21. PMID 18953430 DOI: 10.1016/S1359-6349(08)71222-9  0.458
2008 Yi C, Wilker EW, Yaffe MB, Stemmer-Rachamimov A, Kissil JL. Validation of the p21-activated kinases as targets for inhibition in neurofibromatosis type 2 Cancer Research. 68: 7932-7937. PMID 18829550 DOI: 10.1158/0008-5472.Can-08-0866  0.422
2008 Snuderl M, Chi SN, De Santis SM, Stemmer-Rachamimov AO, Betensky RA, De Girolami U, Kieran MW. Prognostic value of tumor microinvasion and metalloproteinases expression in intracranial pediatric ependymomas. Journal of Neuropathology and Experimental Neurology. 67: 911-20. PMID 18716553 DOI: 10.1097/Nen.0B013E318184F413  0.598
2008 Maguire CA, Meijer DH, LeRoy SG, Tierney LA, Broekman ML, Costa FF, Breakefield XO, Stemmer-Rachamimov A, Sena-Esteves M. Preventing growth of brain tumors by creating a zone of resistance. Molecular Therapy : the Journal of the American Society of Gene Therapy. 16: 1695-702. PMID 18714312 DOI: 10.1038/Mt.2008.168  0.454
2008 Patil S, Perry A, Maccollin M, Dong S, Betensky RA, Yeh TH, Gutmann DH, Stemmer-Rachamimov AO. Immunohistochemical analysis supports a role for INI1/SMARCB1 in hereditary forms of schwannomas, but not in solitary, sporadic schwannomas. Brain Pathology (Zurich, Switzerland). 18: 517-9. PMID 18422762 DOI: 10.1111/J.1750-3639.2008.00155.X  0.478
2008 Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N. Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell. 13: 105-16. PMID 18242511 DOI: 10.1016/J.Ccr.2007.12.027  0.426
2008 Huang S, Vader D, Wang Z, Stemmer-Rachamimov A, Weitz DA, Dai G, Rosen BR, Deisboeck TS. Using magnetic resonance microscopy to study the growth dynamics of a glioma spheroid in collagen I: A case study. Bmc Medical Imaging. 8: 3. PMID 18230155 DOI: 10.1186/1471-2342-8-3  0.347
2008 Gabeau-Lacet D, Grant E, Stemmer-Rachamimov A, Yock T, Tarbell NJ. Sellar abnormalities in female first-degree relatives. Clinical Neurology and Neurosurgery. 110: 202-6. PMID 18035480 DOI: 10.1016/J.Clineuro.2007.09.021  0.771
2008 James MF, Lelke JM, Maccollin M, Plotkin SR, Stemmer-Rachamimov AO, Ramesh V, Gusella JF. Modeling NF2 with human arachnoidal and meningioma cell culture systems: NF2 silencing reflects the benign character of tumor growth. Neurobiology of Disease. 29: 278-92. PMID 17962031 DOI: 10.1016/J.Nbd.2007.09.002  0.432
2008 Kalamarides M, Stemmer-Rachamimov AO, Takahashi M, Han ZY, Chareyre F, Niwa-Kawakita M, Black PM, Carroll RS, Giovannini M. Natural history of meningioma development in mice reveals: a synergy of Nf2 and p16(Ink4a) mutations. Brain Pathology (Zurich, Switzerland). 18: 62-70. PMID 17924978 DOI: 10.1111/J.1750-3639.2007.00105.X  0.468
2007 Lessell S, Kim JW, Hatton MP, Stemmer-Rachamimov A, Thiagalingham S, Rubin PAD. Clinical without histopathological manifestations of inflammation in a patient with primary intraorbital optic nerve sheath meningioma Journal of Neuro-Ophthalmology. 27: 104-106. PMID 17548993 DOI: 10.1097/Wno.0B013E318064E495  0.353
2007 Prabhakar S, Messerli SM, Stemmer-Rachamimov AO, Liu TC, Rabkin S, Martuza R, Breakefield XO. Treatment of implantable NF2 schwannoma tumor models with oncolytic herpes simplex virus G47Delta. Cancer Gene Therapy. 14: 460-7. PMID 17304235 DOI: 10.1038/Sj.Cgt.7701037  0.461
2007 Ditomaso E, Stemmer-Rachamimov A, Potts A, Drottar M, Jain RK, Plotkin SR. Correlation between VEGF expression and MVD in sporadic and NF2-related schwannomas Journal of Clinical Oncology. 25: 2083-2083. DOI: 10.1200/Jco.2007.25.18_Suppl.2083  0.388
2007 Fulci G, Dmitrieva N, Gianni D, Fontana EJ, Pan X, Lu Y, Kaufman CS, Kaur B, Lawler SE, Lee RJ, Marsh CB, Brat DJ, Rooijen NV, Stemmer-Rachamimov AO, Hochberg FH, et al. Erratum: Depletion of peripheral macrophages and brain microglia increases brain tumor titers of oncolytic viruses (Cancer Research (2007) 67, (9398-9406)) Cancer Research. 67. DOI: 10.1158/0008-5472.Can-67-22-Cor  0.35
2005 Brown AB, Mahmood U, Cortes ML, Tang Y, Dai G, Stemmer-Rachamimov A, Prabhakar S, Leishear K, Onda H, Kwiatkowski D, Weissleder R, Breakefield X. Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery Human Gene Therapy. 16: 1367-1376. PMID 16390268 DOI: 10.1089/Hum.2005.16.1367  0.36
2005 Dong S, Nutt CL, Betensky RA, Stemmer-Rachamimov AO, Denko NC, Ligon KL, Rowitch DH, Louis DN. Histology-based expression profiling yields novel prognostic markers in human glioblastoma. Journal of Neuropathology and Experimental Neurology. 64: 948-55. PMID 16254489 DOI: 10.1097/01.Jnen.0000186940.14779.90  0.757
2005 Nunes F, Shen Y, Niida Y, Beauchamp R, Stemmer-Rachamimov AO, Ramesh V, Gusella J, MacCollin M. Inactivation patterns of NF2 and DAL-1/4.1B (EPB41L3) in sporadic meningioma. Cancer Genetics and Cytogenetics. 162: 135-9. PMID 16213361 DOI: 10.1016/J.Cancergencyto.2005.04.003  0.444
2005 MacCollin M, Chiocca EA, Evans DG, Friedman JM, Horvitz R, Jaramillo D, Lev M, Mautner VF, Niimura M, Plotkin SR, Sang CN, Stemmer-Rachamimov A, Roach ES. Diagnostic criteria for schwannomatosis. Neurology. 64: 1838-45. PMID 15955931 DOI: 10.1212/01.Wnl.0000163982.78900.Ad  0.44
2005 Korf BR, Henson JW, Stemmer-Rachamimov A. Case 13-2005: A 48-year-old man with weakness of the limbs and multiple tumors of spinal nerves New England Journal of Medicine. 352: 1800-1808. PMID 15858190 DOI: 10.1056/Nejmcpc059008  0.351
2005 Nutt CL, Betensky RA, Brower MA, Batchelor TT, Louis DN, Stemmer-Rachamimov AO. YKL-40 is a differential diagnostic marker for histologic subtypes of high-grade gliomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 2258-64. PMID 15788675 DOI: 10.1158/1078-0432.Ccr-04-1601  0.777
2005 Perry A, Kurtkaya-Yapicier O, Scheithauer BW, Robinson S, Prayson RA, Kleinschmidt-DeMasters BK, Stemmer-Rachamimov AO, Gutmann DH. Insights into meningioangiomatosis with and without meningioma: a clinicopathologic and genetic series of 24 cases with review of the literature. Brain Pathology (Zurich, Switzerland). 15: 55-65. PMID 15779237 DOI: 10.1111/J.1750-3639.2005.Tb00100.X  0.337
2004 Lee-Jones L, Aligianis I, Davies PA, Puga A, Farndon PA, Stemmer-Rachamimov A, Ramesh V, Sampson JR. Sacrococcygeal chordomas in patients with tuberous sclerosis complex show somatic loss of TSC1 or TSC2 Genes Chromosomes and Cancer. 41: 80-85. PMID 15236319 DOI: 10.1002/Gcc.20052  0.383
2004 Eckstein O, Stemmer-Rachamimov A, Nunes F, Hoch D, Ojemann R, MacCollin M. Multiple meningiomas in brain and lung due to acquired mutation of the NF2 gene. Neurology. 62: 1904-5. PMID 15159511 DOI: 10.1212/01.Wnl.0000125249.36445.Cc  0.466
2004 Stemmer-Rachamimov AO, Louis DN, Nielsen GP, Antonescu CR, Borowsky AD, Bronson RT, Burns DK, Cervera P, McLaughlin ME, Reifenberger G, Schmale MC, MacCollin M, Chao RC, Cichowski K, Kalamarides M, et al. Comparative pathology of nerve sheath tumors in mouse models and humans. Cancer Research. 64: 3718-24. PMID 15150133 DOI: 10.1158/0008-5472.Can-03-4079  0.673
2004 Han S, Santos TM, Puga A, Roy J, Thiele EA, McCollin M, Stemmer-Rachamimov A, Ramesh V. Phosphorylation of Tuberin as a Novel Mechanism for Somatic Inactivation of the Tuberous Sclerosis Complex Proteins in Brain Lesions Cancer Research. 64: 812-816. PMID 14871804 DOI: 10.1158/0008-5472.Can-03-3277  0.447
2003 Heinrich B, Hartmann C, Stemmer-Rachamimov AO, Louis DN, MacCollin M. Multiple meningiomas: Investigating the molecular basis of sporadic and familial forms. International Journal of Cancer. Journal International Du Cancer. 103: 483-8. PMID 12478663 DOI: 10.1002/Ijc.10840  0.73
2001 Niida Y, Stemmer-Rachamimov AO, Logrip M, Tapon D, Perez R, Kwiatkowski DJ, Sims K, MacCollin M, Louis DN, Ramesh V. Survey of somatic mutations in tuberous sclerosis complex (TSC) hamartomas suggests different genetic mechanisms for pathogenesis of TSC lesions. American Journal of Human Genetics. 69: 493-503. PMID 11468687 DOI: 10.1086/321972  0.666
2001 Ino Y, Betensky RA, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Ramsay DA, Cairncross JG, Louis DN. Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 7: 839-45. PMID 11309331  0.719
2001 Murthy V, Stemmer-Rachamimov AO, Haddad LA, Roy JE, Cutone AN, Beauchamp RL, Smith N, Louis DN, Ramesh V. Developmental expression of the tuberous sclerosis proteins tuberin and hamartin. Acta Neuropathologica. 101: 202-10. PMID 11307618 DOI: 10.1007/S004010000269  0.598
2001 Stemmer-Rachamimov AO, Wiederhold T, Nielsen GP, James M, Pinney-Michalowski D, Roy JE, Cohen WA, Ramesh V, Louis DN. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas. The American Journal of Pathology. 158: 57-62. PMID 11141479 DOI: 10.1016/S0002-9440(10)63944-2  0.57
2000 Ino Y, Zlatescu MC, Sasaki H, Macdonald DR, Stemmer-Rachamimov AO, Jhung S, Ramsay DA, von Deimling A, Louis DN, Cairncross JG. Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss. Journal of Neurosurgery. 92: 983-90. PMID 10839259 DOI: 10.3171/Jns.2000.92.6.0983  0.767
1999 Nielsen GP, Stemmer-Rachamimov AO, Ino Y, Moller MB, Rosenberg AE, Louis DN. Malignant transformation of neurofibromas in neurofibromatosis 1 is associated with CDKN2A/p16 inactivation. The American Journal of Pathology. 155: 1879-84. PMID 10595918 DOI: 10.1016/S0002-9440(10)65507-1  0.708
1999 Nielsen GP, Stemmer-Rachamimov AO, Shaw J, Roy JE, Koh J, Louis DN. Immunohistochemical survey of p16INK4A expression in normal human adult and infant tissues. Laboratory Investigation; a Journal of Technical Methods and Pathology. 79: 1137-43. PMID 10496532  0.592
1999 Taylor MD, Perry J, Zlatescu MC, Stemmer-Rachamimov AO, Ang LC, Ino Y, Schwartz M, Becker LE, Louis DN, Cairncross JG. The hPMS2 exon 5 mutation and malignant glioma. Case report. Journal of Neurosurgery. 90: 946-50. PMID 10223463 DOI: 10.3171/jns.1999.90.5.0946  0.724
1998 Stemmer-Rachamimov AO, Nielsen GP, Rosenberg AE, Louis DN, Jones D, Ramesh V, Gusella JF, Jacoby LB. The NF2 gene and merlin protein in human osteosarcomas. Neurogenetics. 2: 73-4. PMID 9933303 DOI: 10.1007/S100480050054  0.589
1998 Stemmer-Rachamimov AO, Ino Y, Lim ZY, Jacoby LB, MacCollin M, Gusella JF, Ramesh V, Louis DN. Loss of the NF2 gene and merlin occur by the tumorlet stage of schwannoma development in neurofibromatosis 2. Journal of Neuropathology and Experimental Neurology. 57: 1164-7. PMID 9862639 DOI: 10.1097/00005072-199812000-00008  0.71
1998 Ohh M, Yauch RL, Lonergan KM, Whaley JM, Stemmer-Rachamimov AO, Louis DN, Gavin BJ, Kley N, Kaelin WG, Iliopoulos O. The von Hippel-Lindau tumor suppressor protein is required for proper assembly of an extracellular fibronectin matrix. Molecular Cell. 1: 959-68. PMID 9651579 DOI: 10.1016/S1097-2765(00)80096-9  0.609
1998 Stemmer-Rachamimov AO, Nielsen GP, Louis DN. EXPRESSION OF THE p16 PROTEIN IN THE HUMAN NERVOUS SYSTEM AND OTHER TISSUES Journal of Neuropathology and Experimental Neurology. 57: 499. DOI: 10.1097/00005072-199805000-00138  0.581
1997 Stemmer-Rachamimov AO, Xu L, Gonzalez-Agosti C, Burwick JA, Pinney D, Beauchamp R, Jacoby LB, Gusella JF, Ramesh V, Louis DN. Universal absence of merlin, but not other ERM family members, in schwannomas. The American Journal of Pathology. 151: 1649-54. PMID 9403715  0.641
1997 Stemmer-Rachamimov AO, Louis DN. Histopathologic and immunohistochemical prognostic factors in malignant gliomas. Current Opinion in Oncology. 9: 230-4. PMID 9229144 DOI: 10.1097/00001622-199709030-00003  0.626
1997 Stemmer-Rachamimov AO, Gonzalez-Agosti C, Xu L, Burwick JA, Beauchamp R, Pinney D, Louis DN, Ramesh V. Expression of NF2-encoded merlin and related ERM family proteins in the human central nervous system. Journal of Neuropathology and Experimental Neurology. 56: 735-42. PMID 9184664 DOI: 10.1097/00005072-199756060-00011  0.62
1997 Stemmer-Rachamimov AO, Horgan MA, Taratuto AL, Munoz DG, Smith TW, Frosch MP, Louis DN. Meningioangiomatosis is associated with neurofibromatosis 2 but not with somatic alterations of the NF2 gene. Journal of Neuropathology and Experimental Neurology. 56: 485-9. PMID 9143261 DOI: 10.1097/00005072-199705000-00004  0.656
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