G. Stanley McKnight - Publications

Affiliations: 
University of Washington, Seattle, Seattle, WA 
Area:
protein kinase A, signal transduction

140 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Yang L, McKnight GS. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nature Communications. 6: 8237. PMID 26381935 DOI: 10.1038/ncomms9237  0.72
2015 Sanz E, Quintana A, Deem JD, Steiner RA, Palmiter RD, McKnight GS. Fertility-regulating Kiss1 neurons arise from hypothalamic POMC-expressing progenitors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5549-56. PMID 25855171 DOI: 10.1523/JNEUROSCI.3614-14.2015  0.72
2015 Gilbert ML, Yang L, Su T, McKnight GS. Expression of a dominant negative PKA mutation in the kidney elicits a diabetes insipidus phenotype. American Journal of Physiology. Renal Physiology. 308: F627-38. PMID 25587115 DOI: 10.1152/ajprenal.00222.2014  0.72
2014 Vulto-van Silfhout AT, Rajamanickam S, Jensik PJ, Vergult S, de Rocker N, Newhall KJ, Raghavan R, Reardon SN, Jarrett K, McIntyre T, Bulinski J, Ownby SL, Huggenvik JI, McKnight GS, Rose GM, et al. Mutations affecting the SAND domain of DEAF1 cause intellectual disability with severe speech impairment and behavioral problems. American Journal of Human Genetics. 94: 649-61. PMID 24726472 DOI: 10.1016/j.ajhg.2014.03.013  0.72
2014 Yang L, Gilbert ML, Zheng R, McKnight GS. Selective expression of a dominant-negative type Iα PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4896-904. PMID 24695708 DOI: 10.1523/JNEUROSCI.3460-13.2014  0.72
2013 Wu Q, Zheng R, Srisai D, McKnight GS, Palmiter RD. NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Proceedings of the National Academy of Sciences of the United States of America. 110: 14765-70. PMID 23964123 DOI: 10.1073/pnas.1314137110  0.72
2013 Sanz E, Evanoff R, Quintana A, Evans E, Miller JA, Ko C, Amieux PS, Griswold MD, McKnight GS. RiboTag analysis of actively translated mRNAs in Sertoli and Leydig cells in vivo. Plos One. 8: e66179. PMID 23776628 DOI: 10.1371/journal.pone.0066179  0.72
2013 Zheng R, Yang L, Sikorski MA, Enns LC, Czyzyk TA, Ladiges WC, McKnight GS. Deficiency of the RIIβ subunit of PKA affects locomotor activity and energy homeostasis in distinct neuronal populations. Proceedings of the National Academy of Sciences of the United States of America. 110: E1631-40. PMID 23569242 DOI: 10.1073/pnas.1219542110  0.72
2012 Quintana A, Sanz E, Wang W, Storey GP, Güler AD, Wanat MJ, Roller BA, La Torre A, Amieux PS, McKnight GS, Bamford NS, Palmiter RD. Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nature Neuroscience. 15: 1547-55. PMID 23064379 DOI: 10.1038/nn.3239  0.72
2012 Jones BW, Brunet S, Gilbert ML, Nichols CB, Su T, Westenbroek RE, Scott JD, Catterall WA, McKnight GS. Cardiomyocytes from AKAP7 knockout mice respond normally to adrenergic stimulation. Proceedings of the National Academy of Sciences of the United States of America. 109: 17099-104. PMID 23035250 DOI: 10.1073/pnas.1215219109  0.72
2011 Gottsch ML, Popa SM, Lawhorn JK, Qiu J, Tonsfeldt KJ, Bosch MA, Kelly MJ, Rønnekleiv OK, Sanz E, McKnight GS, Clifton DK, Palmiter RD, Steiner RA. Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology. 152: 4298-309. PMID 21933870 DOI: 10.1210/en.2011-1521  0.72
2011 Willis BS, Niswender CM, Su T, Amieux PS, McKnight GS. Cell-type specific expression of a dominant negative PKA mutation in mice. Plos One. 6: e18772. PMID 21533282 DOI: 10.1371/journal.pone.0018772  0.72
2011 Nagalla S, Shaw C, Kong X, Kondkar AA, Edelstein LC, Ma L, Chen J, McKnight GS, López JA, Yang L, Jin Y, Bray MS, Leal SM, Dong JF, Bray PF. Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood. 117: 5189-97. PMID 21415270 DOI: 10.1182/blood-2010-09-299719  0.72
2010 Nichols CB, Rossow CF, Navedo MF, Westenbroek RE, Catterall WA, Santana LF, McKnight GS. Sympathetic stimulation of adult cardiomyocytes requires association of AKAP5 with a subpopulation of L-type calcium channels. Circulation Research. 107: 747-56. PMID 20671242 DOI: 10.1161/CIRCRESAHA.109.216127  0.72
2010 Weisenhaus M, Allen ML, Yang L, Lu Y, Nichols CB, Su T, Hell JW, McKnight GS. Mutations in AKAP5 disrupt dendritic signaling complexes and lead to electrophysiological and behavioral phenotypes in mice. Plos One. 5: e10325. PMID 20428246 DOI: 10.1371/journal.pone.0010325  0.72
2010 Amieux PS, McKnight GS. Cyclic nucleotides converge on brown adipose tissue differentiation. Science Signaling. 3: pe2. PMID 20068229 DOI: 10.1126/scisignal.3104pe2  0.72
2009 Enns LC, Morton JF, Mangalindan RS, McKnight GS, Schwartz MW, Kaeberlein MR, Kennedy BK, Rabinovitch PS, Ladiges WC. Attenuation of age-related metabolic dysfunction in mice with a targeted disruption of the Cbeta subunit of protein kinase A. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 1221-31. PMID 19776218 DOI: 10.1093/gerona/glp133  0.72
2009 Sanz E, Yang L, Su T, Morris DR, McKnight GS, Amieux PS. Cell-type-specific isolation of ribosome-associated mRNA from complex tissues. Proceedings of the National Academy of Sciences of the United States of America. 106: 13939-44. PMID 19666516 DOI: 10.1073/pnas.0907143106  0.72
2009 Enns LC, Morton JF, Treuting PR, Emond MJ, Wolf NS, Dai DF, McKnight GS, Rabinovitch PS, Ladiges WC. Disruption of protein kinase A in mice enhances healthy aging. Plos One. 4: e5963. PMID 19536287 DOI: 10.1371/journal.pone.0005963  0.72
2009 Vuong BQ, Lee M, Kabir S, Irimia C, Macchiarulo S, McKnight GS, Chaudhuri J. Specific recruitment of protein kinase A to the immunoglobulin locus regulates class-switch recombination. Nature Immunology. 10: 420-6. PMID 19234474 DOI: 10.1038/ni.1708  0.72
2008 Lu Y, Zhang M, Lim IA, Hall DD, Allen M, Medvedeva Y, McKnight GS, Usachev YM, Hell JW. AKAP150-anchored PKA activity is important for LTD during its induction phase. The Journal of Physiology. 586: 4155-64. PMID 18617570 DOI: 10.1113/jphysiol.2008.151662  0.72
2008 Schnizler K, Shutov LP, Van Kanegan MJ, Merrill MA, Nichols B, McKnight GS, Strack S, Hell JW, Usachev YM. Protein kinase A anchoring via AKAP150 is essential for TRPV1 modulation by forskolin and prostaglandin E2 in mouse sensory neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4904-17. PMID 18463244 DOI: 10.1523/JNEUROSCI.0233-08.2008  0.72
2008 Alizadeh A, Fitch KR, Niswender CM, McKnight GS, Barsh GS. Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements. Pigment Cell & Melanoma Research. 21: 63-9. PMID 18353144 DOI: 10.1111/j.1755-148X.2007.00425.x  0.72
2008 Navedo MF, Nieves-Cintrón M, Amberg GC, Yuan C, Votaw VS, Lederer WJ, McKnight GS, Santana LF. AKAP150 is required for stuttering persistent Ca2+ sparklets and angiotensin II-induced hypertension. Circulation Research. 102: e1-e11. PMID 18174462 DOI: 10.1161/CIRCRESAHA.107.167809  0.72
2008 Czyzyk TA, Sikorski MA, Yang L, McKnight GS. Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 276-81. PMID 18172198 DOI: 10.1073/pnas.0710607105  0.72
2007 Lu Y, Allen M, Halt AR, Weisenhaus M, Dallapiazza RF, Hall DD, Usachev YM, McKnight GS, Hell JW. Age-dependent requirement of AKAP150-anchored PKA and GluR2-lacking AMPA receptors in LTP. The Embo Journal. 26: 4879-90. PMID 17972919 DOI: 10.1038/sj.emboj.7601884  0.72
2007 Lim CJ, Han J, Yousefi N, Ma Y, Amieux PS, McKnight GS, Taylor SS, Ginsberg MH. Alpha4 integrins are type I cAMP-dependent protein kinase-anchoring proteins. Nature Cell Biology. 9: 415-21. PMID 17369818 DOI: 10.1038/ncb1561  0.72
2007 Burton KA, McKnight GS. PKA, germ cells, and fertility. Physiology (Bethesda, Md.). 22: 40-6. PMID 17289929 DOI: 10.1152/physiol.00034.2006  0.72
2007 Hall DD, Davare MA, Shi M, Allen ML, Weisenhaus M, McKnight GS, Hell JW. Critical role of cAMP-dependent protein kinase anchoring to the L-type calcium channel Cav1.2 via A-kinase anchor protein 150 in neurons. Biochemistry. 46: 1635-46. PMID 17279627 DOI: 10.1021/bi062217x  0.72
2006 Yu FH, Mantegazza M, Westenbroek RE, Robbins CA, Kalume F, Burton KA, Spain WJ, McKnight GS, Scheuer T, Catterall WA. Reduced sodium current in GABAergic interneurons in a mouse model of severe myoclonic epilepsy in infancy. Nature Neuroscience. 9: 1142-9. PMID 16921370 DOI: 10.1038/nn1754  0.72
2006 Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/syn.20303  0.72
2006 Burton KA, McDermott DA, Wilkes D, Poulsen MN, Nolan MA, Goldstein M, Basson CT, McKnight GS. Haploinsufficiency at the protein kinase A RI alpha gene locus leads to fertility defects in male mice and men. Molecular Endocrinology (Baltimore, Md.). 20: 2504-13. PMID 16728532 DOI: 10.1210/me.2006-0060  0.72
2006 Watson RF, Abdel-Majid RM, Barnett MW, Willis BS, Katsnelson A, Gillingwater TH, McKnight GS, Kind PC, Neumann PE. Involvement of protein kinase A in patterning of the mouse somatosensory cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 5393-401. PMID 16707791 DOI: 10.1523/JNEUROSCI.0750-06.2006  0.72
2006 Newhall KJ, Criniti AR, Cheah CS, Smith KC, Kafer KE, Burkart AD, McKnight GS. Dynamic anchoring of PKA is essential during oocyte maturation. Current Biology : Cb. 16: 321-7. PMID 16461287 DOI: 10.1016/j.cub.2005.12.031  0.72
2006 Howe DG, Clarke CM, Yan H, Willis BS, Schneider DA, McKnight GS, Kapur RP. Inhibition of protein kinase A in murine enteric neurons causes lethal intestinal pseudo-obstruction. Journal of Neurobiology. 66: 256-72. PMID 16329126 DOI: 10.1002/neu.20217  0.72
2006 Schuh SM, Carlson AE, McKnight GS, Conti M, Hille B, Babcock DF. Signaling pathways for modulation of mouse sperm motility by adenosine and catecholamine agonists. Biology of Reproduction. 74: 492-500. PMID 16291925 DOI: 10.1095/biolreprod.105.047837  0.72
2005 Niswender CM, Willis BS, Wallen A, Sweet IR, Jetton TL, Thompson BR, Wu C, Lange AJ, McKnight GS. Cre recombinase-dependent expression of a constitutively active mutant allele of the catalytic subunit of protein kinase A. Genesis (New York, N.Y. : 2000). 43: 109-19. PMID 16155866 DOI: 10.1002/gene.20159  0.72
2005 Schillace RV, Andrews SF, Galligan SG, Burton KA, Starks HJ, Bouwer HG, McKnight GS, Davey MP, Carr DW. The role of protein kinase A anchoring via the RII alpha regulatory subunit in the murine immune system. Journal of Immunology (Baltimore, Md. : 1950). 174: 6847-53. PMID 15905526  0.72
2005 Newhall KJ, Cummings DE, Nolan MA, McKnight GS. Deletion of the RIIbeta-subunit of protein kinase A decreases body weight and increases energy expenditure in the obese, leptin-deficient ob/ob mouse. Molecular Endocrinology (Baltimore, Md.). 19: 982-91. PMID 15618289 DOI: 10.1210/me.2004-0343  0.72
2004 Fischer QS, Beaver CJ, Yang Y, Rao Y, Jakobsdottir KB, Storm DR, McKnight GS, Daw NW. Requirement for the RIIbeta isoform of PKA, but not calcium-stimulated adenylyl cyclase, in visual cortical plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 9049-58. PMID 15483123 DOI: 10.1523/JNEUROSCI.2409-04.2004  0.72
2004 Veugelers M, Wilkes D, Burton K, McDermott DA, Song Y, Goldstein MM, La Perle K, Vaughan CJ, O'Hagan A, Bennett KR, Meyer BJ, Legius E, Karttunen M, Norio R, Kaariainen H, ... ... McKnight GS, et al. Comparative PRKAR1A genotype-phenotype analyses in humans with Carney complex and prkar1a haploinsufficient mice. Proceedings of the National Academy of Sciences of the United States of America. 101: 14222-7. PMID 15371594 DOI: 10.1073/pnas.0405535101  0.72
2004 Nolan MA, Babcock DF, Wennemuth G, Brown W, Burton KA, McKnight GS. Sperm-specific protein kinase A catalytic subunit Calpha2 orchestrates cAMP signaling for male fertility. Proceedings of the National Academy of Sciences of the United States of America. 101: 13483-8. PMID 15340140 DOI: 10.1073/pnas.0405580101  0.72
2004 Rao Y, Fischer QS, Yang Y, McKnight GS, LaRue A, Daw NW. Reduced ocular dominance plasticity and long-term potentiation in the developing visual cortex of protein kinase A RII alpha mutant mice. The European Journal of Neuroscience. 20: 837-42. PMID 15255994 DOI: 10.1111/j.1460-9568.2004.03499.x  0.72
2004 Nolan MA, Sikorski MA, McKnight GS. The role of uncoupling protein 1 in the metabolism and adiposity of RII beta-protein kinase A-deficient mice. Molecular Endocrinology (Baltimore, Md.). 18: 2302-11. PMID 15192081 DOI: 10.1210/me.2004-0194  0.72
2002 Howe DG, Wiley JC, McKnight GS. Molecular and behavioral effects of a null mutation in all PKA C beta isoforms. Molecular and Cellular Neurosciences. 20: 515-24. PMID 12139926 DOI: 10.1006/mcne.2002.1119  0.72
2002 Amieux PS, McKnight GS. The essential role of RI alpha in the maintenance of regulated PKA activity. Annals of the New York Academy of Sciences. 968: 75-95. PMID 12119269  0.72
2002 Huang Y, Roelink H, McKnight GS. Protein kinase A deficiency causes axially localized neural tube defects in mice. The Journal of Biological Chemistry. 277: 19889-96. PMID 11886853 DOI: 10.1074/jbc.M111412200  0.72
2002 Skålhegg BS, Huang Y, Su T, Idzerda RL, McKnight GS, Burton KA. Mutation of the Calpha subunit of PKA leads to growth retardation and sperm dysfunction. Molecular Endocrinology (Baltimore, Md.). 16: 630-9. PMID 11875122 DOI: 10.1210/mend.16.3.0793  0.72
2001 Schreyer SA, Cummings DE, McKnight GS, LeBoeuf RC. Mutation of the RIIbeta subunit of protein kinase A prevents diet-induced insulin resistance and dyslipidemia in mice. Diabetes. 50: 2555-62. PMID 11679434  0.72
2000 Wu JY, Ribar TJ, Cummings DE, Burton KA, McKnight GS, Means AR. Spermiogenesis and exchange of basic nuclear proteins are impaired in male germ cells lacking Camk4. Nature Genetics. 25: 448-52. PMID 10932193 DOI: 10.1038/78153  0.72
2000 Desseyn JL, Burton KA, McKnight GS. Expression of a nonmyristylated variant of the catalytic subunit of protein kinase A during male germ-cell development. Proceedings of the National Academy of Sciences of the United States of America. 97: 6433-8. PMID 10841548 DOI: 10.1073/pnas.97.12.6433  0.72
2000 Thiele TE, Willis B, Stadler J, Reynolds JG, Bernstein IL, McKnight GS. High ethanol consumption and low sensitivity to ethanol-induced sedation in protein kinase A-mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC75. PMID 10783399  0.72
2000 Gangolli EA, Belyamani M, Muchinsky S, Narula A, Burton KA, McKnight GS, Uhler MD, Idzerda RL. Deficient gene expression in protein kinase inhibitor alpha Null mutant mice. Molecular and Cellular Biology. 20: 3442-8. PMID 10779334 DOI: 10.1128/MCB.20.10.3442-3448.2000  0.72
1999 Planas JV, Cummings DE, Idzerda RL, McKnight GS. Mutation of the RIIbeta subunit of protein kinase A differentially affects lipolysis but not gene induction in white adipose tissue. The Journal of Biological Chemistry. 274: 36281-7. PMID 10593917 DOI: 10.1074/jbc.274.51.36281  0.72
1999 Burton KA, Treash-Osio B, Muller CH, Dunphy EL, McKnight GS. Deletion of type IIα regulatory subunit delocalizes protein kinase A in mouse sperm without affecting motility or fertilization Journal of Biological Chemistry. 274: 24131-24136. PMID 10446185 DOI: 10.1074/jbc.274.34.24131  0.72
1999 Wiley JC, Wailes LA, Idzerda RL, McKnight GS. Role of regulatory subunits and protein kinase inhibitor (PKI) in determining nuclear localization and activity of the catalytic subunit of protein kinase A. The Journal of Biological Chemistry. 274: 6381-7. PMID 10037729 DOI: 10.1074/jbc.274.10.6381  0.72
1998 McKnight GS, Cummings DE, Amieux PS, Sikorski MA, Brandon EP, Planas JV, Motamed K, Idzerda RL. Cyclic AMP, PKA, and the physiological regulation of adiposity. Recent Progress in Hormone Research. 53: 139-59; discussion 1. PMID 9769707  0.72
1998 La Spada AR, Peterson KR, Meadows SA, McClain ME, Jeng G, Chmelar RS, Haugen HA, Chen K, Singer MJ, Moore D, Trask BJ, Fischbeck KH, Clegg CH, McKnight GS. Androgen receptor YAC transgenic mice carrying CAG 45 alleles show trinucleotide repeat instability. Human Molecular Genetics. 7: 959-67. PMID 9580659 DOI: 10.1093/hmg/7.6.959  0.72
1998 Brandon EP, Logue SF, Adams MR, Qi M, Sullivan SP, Matsumoto AM, Dorsa DM, Wehner JM, McKnight GS, Idzerda RL. Defective motor behavior and neural gene expression in RIIbeta-protein kinase A mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3639-49. PMID 9570795  0.72
1998 Hensch TK, Gordon JA, Brandon EP, McKnight GS, Idzerda RL, Stryker MP. Comparison of plasticity in vivo and in vitro in the developing visual cortex of normal and protein kinase A RIbeta-deficient mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2108-17. PMID 9482797  0.72
1997 Burton KA, Johnson BD, Hausken ZE, Westenbroek RE, Idzerda RL, Scheuer T, Scott JD, Catterall WA, McKnight GS. Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 94: 11067-72. PMID 9380760 DOI: 10.1073/pnas.94.20.11067  0.72
1997 Hamilton SE, Loose MD, Qi M, Levey AI, Hille B, McKnight GS, Idzerda RL, Nathanson NM. Disruption of the m1 receptor gene ablates muscarinic receptor-dependent M current regulation and seizure activity in mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 13311-6. PMID 9371842 DOI: 10.1073/pnas.94.24.13311  0.72
1997 Guthrie CR, Skâlhegg BS, McKnight GS. Two novel brain-specific splice variants of the murine Cbeta gene of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 272: 29560-5. PMID 9368018 DOI: 10.1074/jbc.272.47.29560  0.72
1997 Adams MR, Brandon EP, Chartoff EH, Idzerda RL, Dorsa DM, McKnight GS. Loss of haloperidol induced gene expression and catalepsy in protein kinase A-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 12157-61. PMID 9342379 DOI: 10.1073/pnas.94.22.12157  0.72
1997 Malmberg AB, Brandon EP, Idzerda RL, Liu H, McKnight GS, Basbaum AI. Diminished inflammation and nociceptive pain with preservation of neuropathic pain in mice with a targeted mutation of the type I regulatory subunit of cAMP-dependent protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7462-70. PMID 9295392  0.72
1997 Brandon EP, Idzerda RL, McKnight GS. PKA isoforms, neural pathways, and behaviour: making the connection. Current Opinion in Neurobiology. 7: 397-403. PMID 9232801 DOI: 10.1016/S0959-4388(97)80069-4  0.72
1996 Cummings DE, Brandon EP, Planas JV, Motamed K, Idzerda RL, McKnight GS. Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A. Nature. 382: 622-6. PMID 8757131 DOI: 10.1038/382622a0  0.72
1996 Qi M, Zhuo M, SkÃ¥lhegg BS, Brandon EP, Kandel ER, McKnight GS, Idzerda RL. Impaired hippocampal plasticity in mice lacking the Cbeta1 catalytic subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 93: 1571-6. PMID 8643673 DOI: 10.1073/pnas.93.4.1571  0.72
1996 McKnight GS. Genetically lean mice derived by targeted disruption of the rllβ subuntt of protein kinase Journal of Investigative Medicine. 44: 197a.  0.72
1995 Huang YY, Kandel ER, Varshavsky L, Brandon EP, Qi M, Idzerda RL, McKnight GS, Bourtchouladze R. A genetic test of the effects of mutations in PKA on mossy fiber LTP and its relation to spatial and contextual learning. Cell. 83: 1211-22. PMID 8548807  0.72
1995 Brandon EP, Gerhold KA, Qi M, McKnight GS, Idzerda RL. Derivation of novel embryonic stem cell lines and targeting of cyclic AMP-dependent protein kinase genes. Recent Progress in Hormone Research. 50: 403-8. PMID 7740174  0.72
1995 Gjertsen BT, Mellgren G, Otten A, Maronde E, Genieser HG, Jastorff B, Vintermyr OK, McKnight GS, Døskeland SO. Novel (Rp)-cAMPS analogs as tools for inhibition of cAMP-kinase in cell culture. Basal cAMP-kinase activity modulates interleukin-1 beta action. The Journal of Biological Chemistry. 270: 20599-607. PMID 7657638  0.72
1995 Brandon EP, Idzerda RL, McKnight GS. Targeting the mouse genome: a compendium of knockouts (Part III) Current Biology : Cb. 5: 873-81. PMID 7583145 DOI: 10.1016/S0960-9822(95)00177-1  0.72
1995 Brandon EP, Idzerda RL, McKnight GS. Targeting the mouse genome: a compendium of knockouts (Part II) Current Biology : Cb. 5: 758-65. PMID 7583122 DOI: 10.1016/S0960-9822(95)00152-7  0.72
1995 Brandon EP, Zhuo M, Huang YY, Qi M, Gerhold KA, Burton KA, Kandel ER, McKnight GS, Idzerda RL. Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 92: 8851-5. PMID 7568030  0.72
1995 Brandon EP, Idzerda RL, McKnight GS. Knockouts. Targeting the mouse genome: a compendium of knockouts (Part I) Current Biology : Cb. 5: 625-34. PMID 7552173 DOI: 10.1016/S0960-9822(95)00127-8  0.72
1995 McDonald RA, Matthews RP, Idzerda RL, McKnight GS. Basal expression of the cystic fibrosis transmembrane conductance regulator gene is dependent on protein kinase A activity. Proceedings of the National Academy of Sciences of the United States of America. 92: 7560-4. PMID 7543684 DOI: 10.1073/pnas.92.16.7560  0.72
1995 Brandon EP, Idzerda RL, McKnight GS. Targeting the mouse genome: a compedium of knockouts Current Biology. 5: 1073. DOI: 10.1016/S0960-9822(95)00212-0  0.72
1994 Matthews RP, Guthrie CR, Wailes LM, Zhao X, Means AR, McKnight GS. Calcium/calmodulin-dependent protein kinase types II and IV differentially regulate CREB-dependent gene expression. Molecular and Cellular Biology. 14: 6107-16. PMID 8065343  0.72
1994 Cummings DE, Edelhoff S, Disteche CM, McKnight GS. Cloning of a mouse protein kinase A catalytic subunit pseudogene and chromosomal mapping of C subunit isoforms. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 701-6. PMID 7873880 DOI: 10.1007/BF00426076  0.72
1993 Orellana SA, Amieux PS, Zhao X, McKnight GS. Mutations in the catalytic subunit of the cAMP-dependent protein kinase interfere with holoenzyme formation without disrupting inhibition by protein kinase inhibitor. The Journal of Biological Chemistry. 268: 6843-6. PMID 8463209  0.72
1993 Theisen M, Behringer RR, Cadd GG, Brinster RL, McKnight GS. A C/EBP-binding site in the transferrin promoter is essential for expression in the liver but not the brain of transgenic mice. Molecular and Cellular Biology. 13: 7666-76. PMID 8246983  0.72
1992 Rogers KV, Boring LF, McKnight GS, Clegg CH. Promoter for the regulatory type I beta subunit of the 3',5'-cyclic adenosine monophosphate-dependent protein kinase directs transgene expression in the central nervous system. Molecular Endocrinology (Baltimore, Md.). 6: 1756-65. PMID 1448119 DOI: 10.1210/mend.6.10.1448119  0.72
1991 Wang YH, Scott JD, McKnight GS, Krebs EG. A constitutively active holoenzyme form of the cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 88: 2446-50. PMID 1848703  0.72
1991 Otten AD, Parenteau LA, Døskeland S, McKnight GS. Hormonal activation of gene transcription in ras-transformed NIH3T3 cells overexpressing RII alpha and RII beta subunits of the cAMP-dependent protein kinase. The Journal of Biological Chemistry. 266: 23074-82. PMID 1744104  0.72
1991 Schecterson LC, McKnight GS. Role of cyclic adenosine 3',5'-monophosphate-dependent protein kinase in hormone-stimulated beta-endorphin secretion in AtT20 cells. Molecular Endocrinology (Baltimore, Md.). 5: 170-8. PMID 1645451 DOI: 10.1210/mend-5-2-170  0.72
1990 Oyen O, Myklebust F, Scott JD, Cadd GG, McKnight GS, Hansson V, Jahnsen T. Subunits of cyclic adenosine 3',5'-monophosphate-dependent protein kinase show differential and distinct expression patterns during germ cell differentiation: alternative polyadenylation in germ cells gives rise to unique smaller-sized mRNA species. Biology of Reproduction. 43: 46-54. PMID 2393692 DOI: 10.1095/biolreprod43.1.46  0.72
1990 Orellana SA, McKnight GS. The S49 Kin- cell line transcribes and translates a functional mRNA coding for the catalytic subunit of cAMP-dependent protein kinase. The Journal of Biological Chemistry. 265: 3048-53. PMID 2303438  0.72
1990 Rogers KV, Goldman PS, Frizzell RA, McKnight GS. Regulation of Cl- transport in T84 cell clones expressing a mutant regulatory subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 87: 8975-9. PMID 2174170  0.72
1990 Cadd GG, Uhler MD, McKnight GS. Holoenzymes of cAMP-dependent protein kinase containing the neural form of type I regulatory subunit have an increased sensitivity to cyclic nucleotides. The Journal of Biological Chemistry. 265: 19502-6. PMID 2174040  0.72
1989 Huggenvik JI, Craven CM, Idzerda RL, Bernstein S, Kaplan J, McKnight GS. A splicing defect in the mouse transferrin gene leads to congenital atransferrinemia Blood. 74: 482-486. PMID 2752125  0.72
1989 Idzerda RL, Behringer RR, Theisen M, Huggenvik JI, McKnight GS, Brinster RL. Expression from the transferrin gene promoter in transgenic mice Molecular and Cellular Biology. 9: 5154-5162. PMID 2601714  0.72
1989 Otten AD, McKnight GS. Overexpression of the type II regulatory subunit of the cAMP-dependent protein kinase eliminates the type I holoenzyme in mouse cells. The Journal of Biological Chemistry. 264: 20255-60. PMID 2584216  0.72
1989 Clegg CH, Ran W, Uhler MD, McKnight GS. A mutation in the catalytic subunit of protein kinase A prevents myristylation but does not inhibit biological activity. The Journal of Biological Chemistry. 264: 20140-6. PMID 2584209  0.72
1989 Correll LA, Woodford TA, Corbin JD, Mellon PL, McKnight GS. Functional characterization of cAMP-binding mutations in type I protein kinase Journal of Biological Chemistry. 264: 16672-16678. PMID 2550452  0.72
1989 Woodford TA, Correll LA, McKnight GS, Corbin JD. Expression and characterization of mutant forms of the type I regulatory subunit of cAMP-dependent protein kinase. The effect of defective cAMP binding on holoenzyme activation Journal of Biological Chemistry. 264: 13321-13328. PMID 2546952  0.72
1989 Mellon PL, Clegg CH, Correll LA, McKnight GS. Regulation of transcription by cyclic AMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 86: 4887-4891. PMID 2544878  0.72
1988 Clegg CH, Cadd GG, McKnight GS. Genetic characterization of a brain-specific form of the type I regulatory subunit of cAMP-dependent protein kinase Proceedings of the National Academy of Sciences of the United States of America. 85: 3703-3707. PMID 3375237  0.72
1988 Oyen O, Scott JD, Cadd GG, McKnight GS, Krebs EG, Hansson V, Jahnsen T. A unique mRNA species for a regulatory subunit of cAMP-dependent protein kinase is specifically induced in haploid germ cells. Febs Letters. 229: 391-4. PMID 3345850 DOI: 10.1016/0014-5793(88)81163-3  0.72
1988 McKnight GS, Cadd GG, Clegg CH, Otten AD, Correll LA. Expression of wild-type and mutant subunits of the cAMP-dependent protein kinase Cold Spring Harbor Symposia On Quantitative Biology. 53: 111-119. PMID 3254772  0.72
1988 McKnight GS, Clegg CH, Uhler MD, Chrivia JC, Cadd GG, Correll LA, Otten AD. Analysis of the cAMP-dependent protein kinase system using molecular genetic approaches Recent Progress in Hormone Research. 44: 307-335. PMID 3217600  0.72
1988 Sanders MM, McKnight GS. Positive and negative regulatory elements control the steroid-responsive ovalbumin promoter Biochemistry. 27: 6550-6557. PMID 3064812  0.72
1988 McKnight GS, Uhler MD, Clegg CH, Correll LA, Cadd GG. Application of molecular genetic techniques to the cAMP-dependent protein kinase system Methods in Enzymology. 159: 299-311. PMID 2842597  0.72
1988 Otten AD, Sanders MM, McKnight GS. The MMTV LTR promoter is induced by progesterone and dihydrotestosterone but not by estrogen Molecular Endocrinology. 2: 143-147. PMID 2840570  0.72
1988 Chrivia JC, Uhler MD, McKnight GS. Characterization of genomic clones coding for the Cα and Cβ subunits of mouse cAMP-dependent protein kinase Journal of Biological Chemistry. 263: 5739-5744. PMID 2833513  0.72
1987 Uhler MD, McKnight GS. Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase Journal of Biological Chemistry. 262: 15202-15207. PMID 3667630  0.72
1987 Scott JD, Glaccum MB, Zoller MJ, Uhler MD, Helfman DM, McKnight GS, Krebs EG. The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 84: 5192-6. PMID 3037538  0.72
1987 Hedin L, McKnight GS, Lifka J, Durica JM, Richards JS. Tissue distribution and hormonal regulation of messenger ribonucleic acid for regulatory and catalytic subunits of adenosine 3',5'-monophosphate-dependent protein kinases during ovarian follicular development and luteinization in the rat. Endocrinology. 120: 1928-35. PMID 3032573 DOI: 10.1210/endo-120-5-1928  0.72
1987 Huggenvik JI, Idzerda RL, Haywood L, Lee DC, McKnight GS, Griswold MD. Transferrin messenger ribonucleic acid: Molecular cloning and hormonal regulation in rat Sertoli cells Endocrinology. 120: 332-340. PMID 3023031  0.72
1987 Clegg CH, Correll LA, Cadd GG, McKnight GS. Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit Journal of Biological Chemistry. 262: 13111-13119. PMID 2820963  0.72
1987 Goldman MA, Stokes KR, Idzerda RL, McKnight GS, Hammer RE, Brinster RL, Gartler SM. A chicken transferrin gene in transgenic mice escapes X-chromosome inactivation. Science (New York, N.Y.). 236: 593-5. PMID 2437652  0.72
1986 Hammer RE, Idzerda RL, Brinster RL, McKnight GS. Estrogen regulation of the avian transferrin gene in transgenic mice Molecular and Cellular Biology. 6: 1010-1014. PMID 3785157  0.72
1986 Idzerda RL, Huebers H, Finch CA, McKnight GS. Rat transferrin gene expression: Tissue-specific regulation by iron deficiency Proceedings of the National Academy of Sciences of the United States of America. 83: 3723-3727. PMID 3459151  0.72
1986 Uhler MD, Carmichael DF, Lee DC, Chrivia JC, Krebs EG, McKnight GS. Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 83: 1300-4. PMID 3456589  0.72
1986 Uhler MD, Chrivia JC, McKnight GS. Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase Journal of Biological Chemistry. 261: 15360-15363. PMID 3023318  0.72
1985 Sanders MM, McKnight GS. Chicken egg white genes: Multihormonal regulation in a primary cell culture system Endocrinology. 116: 398-405. PMID 3880544  0.72
1984 Ebert KM, Paynton BV, McKnight GS, Brinster RL. Translation and stability of ovalbumin messenger RNA injected into growing oocytes and fertilized ova of mice Journal of Embryology and Experimental Morphology. 91-103. PMID 6543452  0.72
1984 Evans MI, McKnight GS. Regulation of the ovalbumin gene: Effects of insulin, adenosine 3',5'-monophosphate, and estrogen Endocrinology. 115: 368-377. PMID 6329659  0.72
1983 Lee DC, Carmichael DF, Krebs EG, McKnight GS. Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 80: 3608-12. PMID 6190178  0.72
1981 Palmiter RD, Mulvihill ER, Shepherd JH, McKnight GS. Steroid hormone regulation of ovalbumin and conalbumin gene transcription. A model based upon multiple regulatory sites and intermediary proteins Journal of Biological Chemistry. 256: 7910-7916. PMID 7263632  0.72
1981 Compere SJ, McKnight GS, Palmiter RD. Androgens regulate ovomucoid and ovalbumin gene expression independently of estrogen Journal of Biological Chemistry. 256: 6341-6347. PMID 7240208  0.72
1981 Evans MI, Hager LJ, McKnight GS. A somatomedin-like peptide hormone is required during the estrogen-mediated induction of ovalbumin gene transcription Cell. 25: 187-193. PMID 7023694 DOI: 10.1016/0092-8674(81)90243-9  0.72
1980 McKnight GS, Hager L, Palmiter RD. Butyrate and related inhibitors of histone deacetylation block the induction of egg white genes by steroid hormones Cell. 22: 469-477. PMID 7448870  0.72
1980 Hager LJ, McKnight GS, Palmiter RD. Glucocorticoid induction of egg white mRNAs in chick oviduct Journal of Biological Chemistry. 255: 7796-7800. PMID 7400146  0.72
1980 McKnight GS, Lee DC, Palmiter RD. Transferrin gene expression. Regulation of mRNA transcription in chick liver by steroid hormones and iron deficiency Journal of Biological Chemistry. 255: 148-153. PMID 7350148  0.72
1980 McKnight GS, Lee DC, Hemmaplardh D, Finch CA, Palmiter RD. Transferrin gene expression. Effects of nutritional iron deficiency Journal of Biological Chemistry. 255: 144-147. PMID 7350147  0.72
1980 Lee DC, McKnight GS, Palmiter RD. The chicken transferrin gene. Restriction endonuclease analysis of gene sequences in liver and oviduct DNA Journal of Biological Chemistry. 255: 1442-1450. PMID 6243638  0.72
1979 McKnight GS, Palmiter RD. Transcriptional regulation of the ovalbumin and conalbumin genes by steroids in chick oviduct Journal of Biological Chemistry. 254: 9050-9058. PMID 479179  0.72
1979 Cochet M, Perrin F, Gannon F, Krust A, Chambon P, Mcknight GS, Lee DC, Mayo KE, Palmiter R. Cloning of an almost full-length chicken conalbumin double-stranded cDNA Nucleic Acids Research. 6: 2435-2452. PMID 88720 DOI: 10.1093/nar/6.7.2435  0.72
1978 Lee DC, McKnight GS, Palmiter RD. The action of estrogen and progesterone on the expression of the transferrin gene. A comparison of the response in chick liver and oviduct Journal of Biological Chemistry. 253: 3494-3503. PMID 649584  0.72
1977 Schimke RT, Pennequin P, Robins D, McKnight GS. Effects of estrogen and progesterone on ovalbumin synthesis in the withdrawn oviduct. Annals of the New York Academy of Sciences. 286: 116-24. PMID 281168  0.72
1977 Palmiter RD, Mulvihill ER, McKnight GS, Senear AW. Regulation of gene expression in the chick oviduct by steroid hormones Cold Spring Harbor Symposia On Quantitative Biology. 42: 639-647. PMID 277311  0.72
1976 Kiely ML, McKnight GS, Schimke RT. Studies on the attachment of carbohydrate to ovalbumin nascent chains in hen oviduct. The Journal of Biological Chemistry. 251: 5490-5. PMID 965372  0.72
1975 McKnight GS, Pennequin P, Schimke RT. Induction of ovalbumin mRNA sequences by estrogen and progesterone in chick oviduct as measured by hybridization to complementary DNA. The Journal of Biological Chemistry. 250: 8105-10. PMID 1176463  0.72
1975 Schimke RT, Shapiro DJ, McKnight GS. Ovalbumin mRNA and ovalbumin DNA and the molecular biology of steroid hormone action. Advances in Experimental Medicine and Biology. 62: 79-101. PMID 1106137  0.72
1975 Schimke RT, McKnight GS, Shapiro DJ, Sullivan D, Palacios R. Hormonal regulation of ovalbumin synthesis in the chick oviduct. Recent Progress in Hormone Research. 31: 175-211. PMID 1105717  0.72
1974 Shapiro DJ, Taylor JM, McKnight GS, Palacios R, Gonzalez C, Kiely ML, Schimke RT. Isolation of hen oviduct ovalbumin and rat live albumin polysomes by indirect immunoprecipitation. The Journal of Biological Chemistry. 249: 3665-71. PMID 4545827  0.72
1974 McKnight GS, Schimke RT. Ovalbumin messenger RNA: evidence that the initial product of transcription is the same size as polysomal ovalbumin messenger. Proceedings of the National Academy of Sciences of the United States of America. 71: 4327-31. PMID 4530986  0.72
1973 Rhoads RE, McKnight GS, Schimke RT. Quantitative measurement of ovalbumin messenger ribonucleic acid activity. Localization in polysomes, induction by estrogen, and effect of actinomycin D. The Journal of Biological Chemistry. 248: 2031-9. PMID 4690592  0.72
1971 Rhoads RE, McKnight GS, Schimke RT. Synthesis of ovalbumin in a rabbit reticulocyte cell-free system programmed with hen oviduct ribonucleic acid. The Journal of Biological Chemistry. 246: 7407-10. PMID 5129730  0.72
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