Year |
Citation |
Score |
2024 |
Toral-Rios D, Long JM, Ulrich JD, Yu J, Strickland MR, Han X, Holtzman DM, Cashikar AG, Paul SM. Cholesterol 25-hydroxylase mediates neuroinflammation and neurodegeneration in a mouse model of tauopathy. The Journal of Experimental Medicine. 221. PMID 38442267 DOI: 10.1084/jem.20232000 |
0.315 |
|
2019 |
Shi Y, Manis M, Long J, Wang K, Sullivan PM, Remolina Serrano J, Hoyle R, Holtzman DM. Microglia drive APOE-dependent neurodegeneration in a tauopathy mouse model. The Journal of Experimental Medicine. PMID 31601677 DOI: 10.1084/Jem.20190980 |
0.407 |
|
2019 |
Long JM, Holtzman DM. Alzheimer Disease: An Update on Pathobiology and Treatment Strategies. Cell. 179: 312-339. PMID 31564456 DOI: 10.1016/J.Cell.2019.09.001 |
0.38 |
|
2018 |
Long JM, Maloney B, Rogers JT, Lahiri DK. Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease. Molecular Psychiatry. PMID 30470799 DOI: 10.1038/S41380-018-0266-3 |
0.573 |
|
2015 |
Lahiri DK, Maloney B, Long J, Chopra N, Bayon BL, Greig NH, Sambamurti K, Spence J, Ray B. P2-048: Does the mini-mental state examination (MMSE) measure a deeper biological process? modeling mmse score versus three selected mirna levels may reveal pathological roles in Alzheimer's disease progression Alzheimer's & Dementia. 11: P499-P500. DOI: 10.1016/J.Jalz.2015.06.584 |
0.525 |
|
2014 |
Ray B, Chopra N, Long JM, Lahiri DK. Human primary mixed brain cultures: preparation, differentiation, characterization and application to neuroscience research. Molecular Brain. 7: 63. PMID 25223359 DOI: 10.1186/S13041-014-0063-0 |
0.481 |
|
2014 |
Lahiri DK, Maloney B, Long JM, Greig NH. Lessons from a BACE1 inhibitor trial: off-site but not off base. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S411-9. PMID 24530026 DOI: 10.1016/J.Jalz.2013.11.004 |
0.545 |
|
2014 |
Long JM, Ray B, Lahiri DK. MicroRNA-339-5p down-regulates protein expression of β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) in human primary brain cultures and is reduced in brain tissue specimens of Alzheimer disease subjects. The Journal of Biological Chemistry. 289: 5184-98. PMID 24352696 DOI: 10.1074/Jbc.M113.518241 |
0.611 |
|
2014 |
Lahiri DK, Long JM. P4-219: MICRORNA-339-5P IS DYSREGULATED IN ALZHEIMER'S DISEASE AND IS INVERSELY PROPORTIONAL TO BACE1 EXPRESSION: IMPLICATION IN TESTING NOVEL DRUG TARGETS Alzheimer's & Dementia. 10: P868-P868. DOI: 10.1016/J.Jalz.2014.05.1737 |
0.5 |
|
2013 |
Lahiri D, Long J, Chopra N, Ray B. O5-06-02: MicroRNA-346 stimulates APP expression by blockading an iron response element in the APP 5'-UTR: A novel therapeutic target for Alzheimer's disease (AD) Alzheimer's & Dementia. 9: P839-P839. DOI: 10.1016/J.Jalz.2013.04.500 |
0.554 |
|
2012 |
Long JM, Ray B, Lahiri DK. MicroRNA-153 physiologically inhibits expression of amyloid-β precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. The Journal of Biological Chemistry. 287: 31298-310. PMID 22733824 DOI: 10.1074/Jbc.M112.366336 |
0.588 |
|
2012 |
Long JM, Lahiri DK. Advances in microRNA experimental approaches to study physiological regulation of gene products implicated in CNS disorders. Experimental Neurology. 235: 402-18. PMID 22245616 DOI: 10.1016/J.Expneurol.2011.12.043 |
0.505 |
|
2012 |
Lahiri D, Long J, Ray B. P4-316: A specific microRNA (miR-339-5p) is reduced in Alzheimer's disease brain and able to lower BACE1 and BETA-AMYLOID peptide levels in human fetal brain cultures, suggesting a novel drug target for ALZHEIMER'S Alzheimer's & Dementia. 8: S769-S769. DOI: 10.1016/J.Jalz.2013.08.097 |
0.591 |
|
2011 |
Ray B, Long JM, Sokol DK, Lahiri DK. Increased secreted amyloid precursor protein-α (sAPPα) in severe autism: proposal of a specific, anabolic pathway and putative biomarker. Plos One. 6: e20405. PMID 21731612 DOI: 10.1371/Journal.Pone.0020405 |
0.484 |
|
2011 |
Long JM, Lahiri DK. Current drug targets for modulating Alzheimer's amyloid precursor protein: role of specific micro-RNA species. Current Medicinal Chemistry. 18: 3314-21. PMID 21728971 DOI: 10.2174/092986711796504592 |
0.544 |
|
2011 |
Sokol DK, Maloney B, Long JM, Ray B, Lahiri DK. Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links. Neurology. 76: 1344-52. PMID 21482951 DOI: 10.1212/Wnl.0B013E3182166Dc7 |
0.56 |
|
2011 |
Long JM, Lahiri DK. MicroRNA-101 downregulates Alzheimer's amyloid-β precursor protein levels in human cell cultures and is differentially expressed. Biochemical and Biophysical Research Communications. 404: 889-95. PMID 21172309 DOI: 10.1016/J.Bbrc.2010.12.053 |
0.564 |
|
2011 |
Lahiri DK, Long JM, Ray B, Sokol D. Biochemical evidence for the dysregulation of Alzheimer’s Amyloid Precursor Protein (APP) expression and metabolism in Fragile X Syndrome (FXS) and severe autism F1000research. 2. DOI: 10.7490/F1000Research.1597.1 |
0.488 |
|
2011 |
Long J, Lahiri D. P3-157: A novel microRNA interaction relevant to alzheimer's disease pathogenesis and drug target discovery: miR-346 induces expression of amyloid precursor protein Alzheimer's & Dementia. 7: S566-S567. DOI: 10.1016/J.Jalz.2011.05.1597 |
0.59 |
|
2010 |
Long JM, Lahiri DK. S4-03-03: Novel Specific MicroRNAs in Regulating Neuronal Genes Implicated In Alzheimer's Disease Alzheimer's & Dementia. 6: e13-e13. DOI: 10.1016/J.Jalz.2010.08.042 |
0.521 |
|
2010 |
Lahiri DK, Bailey JA, Ray B, Tanila H, Banerjee P, Long J. P3-438: The effect of memantine and rivastigmine on synaptic markers and amyloid processing in cell culture and animal models of Alzheimer's disease Alzheimer's & Dementia. 6: S581-S582. DOI: 10.1016/J.Jalz.2010.05.1980 |
0.525 |
|
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