Kumar Sambamurti - Publications

Affiliations: 
Medical University of South Carolina, Charleston, SC, United States 
Area:
Neuroscience Biology

81 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Pappolla MA, Matsubara E, Vidal R, Pacheco-Quinto J, Poeggeler B, Zagorski M, Sambamurti K. Melatonin treatment enhances Aβ lymphatic clearance in a transgenic mouse model of amyloidosis. Current Alzheimer Research. PMID 29637859 DOI: 10.2174/1567205015666180411092551  0.44
2015 Kindy MS, Akyol Ö, Sambamurti K. Preface. Turkish Journal of Medical Sciences. 45: i-ii. PMID 26738336  0.44
2015 Baranello RJ, Bharani KL, Padmaraju V, Chopra N, Lahiri DK, Greig NH, Pappolla MA, Sambamurti K. Amyloid-beta protein clearance and degradation (ABCD) pathways and their role in Alzheimer's disease. Current Alzheimer Research. 12: 32-46. PMID 25523424 DOI: 10.2174/1567205012666141218140953  0.44
2015 Wang X, Zhu M, Hjorth E, Cortés-Toro V, Eyjolfsdottir H, Graff C, Nennesmo I, Palmblad J, Eriksdotter M, Sambamurti K, Fitzgerald JM, Serhan CN, Granholm AC, Schultzberg M. Resolution of inflammation is altered in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 40-50.e1-2. PMID 24530025 DOI: 10.1016/j.jalz.2013.12.024  0.44
2014 Zhao Y, Bhattacharjee S, Jones BM, Hill JM, Clement C, Sambamurti K, Dua P, Lukiw WJ. Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer's Disease (AD) and Age-Related Macular Degeneration (AMD). Molecular Neurobiology. PMID 25204496 DOI: 10.1007/s12035-014-8886-3  0.44
2014 Greig NH, Sambamurti K, Lahiri DK, Becker RE. Amyloid-β precursor protein synthesis inhibitors for Alzheimer's disease treatment. Annals of Neurology. 76: 629-30. PMID 25146731 DOI: 10.1002/ana.24254  0.44
2014 Barnwell E, Padmaraju V, Baranello R, Pacheco-Quinto J, Crosson C, Ablonczy Z, Eckman E, Eckman CB, Ramakrishnan V, Greig NH, Pappolla MA, Sambamurti K. Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein. Plos One. 9: e91531. PMID 24658363 DOI: 10.1371/journal.pone.0091531  0.44
2014 Greig NH, Tweedie D, Rachmany L, Li Y, Rubovitch V, Schreiber S, Chiang YH, Hoffer BJ, Miller J, Lahiri DK, Sambamurti K, Becker RE, Pick CG. Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S62-75. PMID 24529527 DOI: 10.1016/j.jalz.2013.12.011  0.44
2014 Pappolla M, Sambamurti K, Vidal R, Pacheco-Quinto J, Poeggeler B, Matsubara E. Evidence for lymphatic Aβ clearance in Alzheimer's transgenic mice Neurobiology of Disease. 71: 215-219. DOI: 10.1016/j.nbd.2014.07.012  0.44
2013 Pinnix I, Ghiso JA, Pappolla MA, Sambamurti K. Major carboxyl terminal fragments generated by γ-secretase processing of the Alzheimer amyloid precursor are 50 and 51 amino acids long. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 21: 474-83. PMID 23570890 DOI: 10.1016/j.jagp.2013.02.009  0.44
2013 Yu QS, Reale M, Kamal MA, Holloway HW, Luo W, Sambamurti K, Ray B, Lahiri DK, Rogers JT, Greig NH. Synthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholinergic action. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 12: 117-28. PMID 23360256 DOI: 10.2174/1871523011312020003  0.44
2012 Maloney B, Sambamurti K, Zawia N, Lahiri DK. Applying epigenetics to Alzheimer's disease via the latent early-life associated regulation (LEARn) model. Current Alzheimer Research. 9: 589-99. PMID 22300406  0.44
2011 Ablonczy Z, Dahrouj M, Tang PH, Liu Y, Sambamurti K, Marmorstein AD, Crosson CE. Human retinal pigment epithelium cells as functional models for the RPE in vivo. Investigative Ophthalmology & Visual Science. 52: 8614-20. PMID 21960553 DOI: 10.1167/iovs.11-8021  0.44
2011 Britton GB, Smith MA, Perry G, Sambamurti K, Jagannatha Rao KS. Drug discovery for neurodegenerative diseases: challenges and novel biochemical targets dedicated to the memory of Mark A. Smith for his inspiring contribution to Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 24: 1-2. PMID 21525570 DOI: 10.3233/JAD-2011-110021  0.44
2011 Yu J, Gattoni-Celli M, Zhu H, Bhat NR, Sambamurti K, Gattoni-Celli S, Kindy MS. Vitamin D3-enriched diet correlates with a decrease of amyloid plaques in the brain of AβPP transgenic mice. Journal of Alzheimer's Disease : Jad. 25: 295-307. PMID 21422528 DOI: 10.3233/JAD-2011-101986  0.44
2011 Sambamurti K, Greig NH, Utsuki T, Barnwell EL, Sharma E, Mazell C, Bhat NR, Kindy MS, Lahiri DK, Pappolla MA. Targets for AD treatment: conflicting messages from γ-secretase inhibitors. Journal of Neurochemistry. 117: 359-74. PMID 21320126 DOI: 10.1111/j.1471-4159.2011.07213.x  0.44
2010 Poeggeler B, Sambamurti K, Siedlak SL, Perry G, Smith MA, Pappolla MA. A novel endogenous indole protects rodent mitochondria and extends rotifer lifespan. Plos One. 5: e10206. PMID 20421998 DOI: 10.1371/Journal.Pone.0010206  0.44
2010 Prakasam A, Muthuswamy A, Ablonczy Z, Greig NH, Fauq A, Rao KJ, Pappolla MA, Sambamurti K. Differential accumulation of secreted AbetaPP metabolites in ocular fluids. Journal of Alzheimer's Disease : Jad. 20: 1243-53. PMID 20413851 DOI: 10.3233/JAD-2010-100210  0.44
2010 Li Y, Duffy KB, Ottinger MA, Ray B, Bailey JA, Holloway HW, Tweedie D, Perry T, Mattson MP, Kapogiannis D, Sambamurti K, Lahiri DK, Greig NH. GLP-1 receptor stimulation reduces amyloid-beta peptide accumulation and cytotoxicity in cellular and animal models of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 1205-19. PMID 20308787 DOI: 10.3233/Jad-2010-1314  0.44
2010 Ramesh BN, Rao TS, Prakasam A, Sambamurti K, Rao KS. Neuronutrition and Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 1123-39. PMID 20308778 DOI: 10.3233/JAD-2010-1312  0.36
2010 Zambón D, Quintana M, Mata P, Alonso R, Benavent J, Cruz-Sánchez F, Gich J, Pocoví M, Civeira F, Capurro S, Bachman D, Sambamurti K, Nicholas J, Pappolla MA. Higher incidence of mild cognitive impairment in familial hypercholesterolemia. The American Journal of Medicine. 123: 267-74. PMID 20193836 DOI: 10.1016/J.Amjmed.2009.08.015  0.44
2009 Sambamurti K, Jagannatha Rao KS, Pappolla MA. Frontiers in the pathogenesis of Alzheimer's disease. Indian Journal of Psychiatry. 51: S56-60. PMID 21416019  0.44
2009 Ablonczy Z, Prakasam A, Fant J, Fauq A, Crosson C, Sambamurti K. Pigment epithelium-derived factor maintains retinal pigment epithelium function by inhibiting vascular endothelial growth factor-R2 signaling through gamma-secretase. The Journal of Biological Chemistry. 284: 30177-86. PMID 19723623 DOI: 10.1074/jbc.M109.032391  0.36
2009 Hegde ML, Bharathi P, Suram A, Venugopal C, Jagannathan R, Poddar P, Srinivas P, Sambamurti K, Rao KJ, Scancar J, Messori L, Zecca L, Zatta P. Challenges associated with metal chelation therapy in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 17: 457-68. PMID 19363258 DOI: 10.3233/JAD-2009-1068  0.44
2009 Li Y, Perry T, Kindy MS, Harvey BK, Tweedie D, Holloway HW, Powers K, Shen H, Egan JM, Sambamurti K, Brossi A, Lahiri DK, Mattson MP, Hoffer BJ, Wang Y, et al. GLP-1 receptor stimulation preserves primary cortical and dopaminergic neurons in cellular and rodent models of stroke and Parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 106: 1285-90. PMID 19164583 DOI: 10.1073/Pnas.0806720106  0.44
2009 Lockrow J, Prakasam A, Huang P, Bimonte-Nelson H, Sambamurti K, Granholm AC. Cholinergic degeneration and memory loss delayed by vitamin E in a Down syndrome mouse model. Experimental Neurology. 216: 278-89. PMID 19135442 DOI: 10.1016/j.expneurol.2008.11.021  0.44
2008 Zhuo JM, Prakasam A, Murray ME, Zhang HY, Baxter MG, Sambamurti K, Nicolle MM. An increase in Abeta42 in the prefrontal cortex is associated with a reversal-learning impairment in Alzheimer's disease model Tg2576 APPsw mice. Current Alzheimer Research. 5: 385-91. PMID 18690835 DOI: 10.2174/156720508785132280  0.44
2008 Venugopal C, Demos CM, Rao KS, Pappolla MA, Sambamurti K. Beta-secretase: structure, function, and evolution. Cns & Neurological Disorders Drug Targets. 7: 278-94. PMID 18673212 DOI: 10.2174/187152708784936626  0.44
2008 Lahiri DK, Zawia NH, Greig NH, Sambamurti K, Maloney B. Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model. Biogerontology. 9: 375-9. PMID 18668339 DOI: 10.1007/s10522-008-9162-6  0.44
2008 Sambamurti K, Pappolla MA, Jagannatha Rao KS. Value in development of a TAPIR-like mouse monoclonal antibody to Abeta. Journal of Alzheimer's Disease : Jad. 14: 175-7. PMID 18663823 DOI: 10.3233/Jad-2008-14205  0.44
2008 Granholm AC, Bimonte-Nelson HA, Moore AB, Nelson ME, Freeman LR, Sambamurti K. Effects of a saturated fat and high cholesterol diet on memory and hippocampal morphology in the middle-aged rat. Journal of Alzheimer's Disease : Jad. 14: 133-45. PMID 18560126 DOI: 10.3233/Jad-2008-14202  0.44
2008 Thirumangalakudi L, Prakasam A, Zhang R, Bimonte-Nelson H, Sambamurti K, Kindy MS, Bhat NR. High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice Journal of Neurochemistry. 106: 475-485. PMID 18410513 DOI: 10.1111/j.1471-4159.2008.05415.x  0.44
2008 Vasudevaraju P, Bharathi, Garruto RM, Sambamurti K, Rao KSJ. Role of DNA dynamics in Alzheimer's disease Brain Research Reviews. 58: 136-148. PMID 18342372 DOI: 10.1016/j.brainresrev.2008.01.001  0.44
2008 Zhou Y, Suram A, Venugopal C, Prakasam A, Lin S, Su Y, Li B, Paul SM, Sambamurti K. Geranylgeranyl pyrophosphate stimulates gamma-secretase to increase the generation of Abeta and APP-CTFgamma. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 47-54. PMID 17666454 DOI: 10.1096/Fj.07-8175Com  0.44
2007 Venugopal C, Pappolla MA, Sambamurti K. Insulysin cleaves the APP cytoplasmic fragment at multiple sites. Neurochemical Research. 32: 2225-34. PMID 17701350 DOI: 10.1007/s11064-007-9449-z  0.44
2007 Williams B, Granholm AC, Sambamurti K. Age-dependent loss of NGF signaling in the rat basal forebrain is due to disrupted MAPK activation. Neuroscience Letters. 413: 110-4. PMID 17182181 DOI: 10.1016/j.neulet.2006.11.040  0.44
2006 Lahiri DK, Ge YW, Rogers JT, Sambamurti K, Greig NH, Maloney B. Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors. Current Alzheimer Research. 3: 475-83. PMID 17168646 DOI: 10.2174/156720506779025224  0.44
2006 Suram A, Venugopal C, Prakasam A, Sambamurti K. Genotoxicity in Alzheimer's disease: role of amyloid. Current Alzheimer Research. 3: 365-75. PMID 17017867  0.44
2006 Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, et al. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 51: 29-42. PMID 16815330 DOI: 10.1016/J.Neuron.2006.05.022  0.44
2006 Pacheco-Quinto J, Rodriguez de Turco EB, DeRosa S, Howard A, Cruz-Sanchez F, Sambamurti K, Refolo L, Petanceska S, Pappolla MA. Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels. Neurobiology of Disease. 22: 651-6. PMID 16516482 DOI: 10.1016/j.nbd.2006.01.005  0.44
2006 Sambamurti K, Suram A, Venugopal C, Prakasam A, Zhou Y, Lahiri DK, Greig NH. A partial failure of membrane protein turnover may cause Alzheimer's disease: a new hypothesis. Current Alzheimer Research. 3: 81-90. PMID 16472208 DOI: 10.2174/156720506775697142  0.44
2005 Granholm AC, Bachman D, Mintzer J, Sambamurti K. Commentary: "Ceramide and cholesterol: possible connections between normal aging of the brain and Alzheimer's disease. Just hypotheses or molecular pathways to be identified?" by Claudio Costantini, Rekha M.K. Kolasani, Luigi Puglielli. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 1: 53-4. PMID 19595818 DOI: 10.1016/j.jalz.2005.06.010  0.44
2005 Greig NH, Utsuki T, Ingram DK, Wang Y, Pepeu G, Scali C, Yu QS, Mamczarz J, Holloway HW, Giordano T, Chen D, Furukawa K, Sambamurti K, Brossi A, Lahiri DK. Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers Alzheimer beta-amyloid peptide in rodent. Proceedings of the National Academy of Sciences of the United States of America. 102: 17213-8. PMID 16275899 DOI: 10.1073/Pnas.0508575102  0.44
2004 Greig NH, Mattson MP, Perry T, Chan SL, Giordano T, Sambamurti K, Rogers JT, Ovadia H, Lahiri DK. New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists. Annals of the New York Academy of Sciences. 1035: 290-315. PMID 15681814 DOI: 10.1196/Annals.1332.018  0.44
2004 Lahiri DK, Rogers JT, Greig NH, Sambamurti K. Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents. Current Pharmaceutical Design. 10: 3111-9. PMID 15544501 DOI: 10.2174/1381612043383331  0.44
2004 Sambamurti K, Granholm AC, Kindy MS, Bhat NR, Greig NH, Lahiri DK, Mintzer JE. Cholesterol and Alzheimer's disease: clinical and experimental models suggest interactions of different genetic, dietary and environmental risk factors. Current Drug Targets. 5: 517-28. PMID 15270198 DOI: 10.2174/1389450043345335  0.44
2004 Greig NH, Giordano T, Zhu X, Yu QS, Perry TA, Holloway HW, Brossi A, Rogers JT, Sambamurti K, Lahiri DK. Thalidomide-based TNF-alpha inhibitors for neurodegenerative diseases. Acta Neurobiologiae Experimentalis. 64: 1-9. PMID 15190675  0.44
2004 Lahiri DK, Sambamurti K, Bennett DA. Apolipoprotein gene and its interaction with the environmentally driven risk factors: molecular, genetic and epidemiological studies of Alzheimer's disease. Neurobiology of Aging. 25: 651-60. PMID 15172744 DOI: 10.1016/J.Neurobiolaging.2003.12.024  0.44
2004 Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. The Journal of Biological Chemistry. 279: 34674-81. PMID 15148325 DOI: 10.1074/Jbc.M402324200  0.44
2004 Ge YW, Maloney B, Sambamurti K, Lahiri DK. Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1037-9. PMID 15059977 DOI: 10.1096/fj.03-1379fje  0.44
2004 Sambamurti K, Kinsey R, Maloney B, Ge YW, Lahiri DK. Gene structure and organization of the human beta-secretase (BACE) promoter. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 1034-6. PMID 15059975 DOI: 10.1096/fj.03-1378fje  0.44
2003 Marlow L, Cain M, Pappolla MA, Sambamurti K. Beta-secretase processing of the Alzheimer's amyloid protein precursor (APP). Journal of Molecular Neuroscience : Mn. 20: 233-9. PMID 14501002 DOI: 10.1385/JMN:20:3:233  0.44
2003 Marlow L, Canet RM, Haugabook SJ, Hardy JA, Lahiri DK, Sambamurti K. APH1, PEN2, and Nicastrin increase Abeta levels and gamma-secretase activity. Biochemical and Biophysical Research Communications. 305: 502-9. PMID 12763021 DOI: 10.1016/S0006-291X(03)00797-6  0.44
2003 Miller BC, Eckman EA, Sambamurti K, Dobbs N, Chow KM, Eckman CB, Hersh LB, Thiele DL. Amyloid-beta peptide levels in brain are inversely correlated with insulysin activity levels in vivo. Proceedings of the National Academy of Sciences of the United States of America. 100: 6221-6. PMID 12732730 DOI: 10.1073/pnas.1031520100  0.44
2003 Lahiri DK, Farlow MR, Sambamurti K, Greig NH, Giacobini E, Schneider LS. A critical analysis of new molecular targets and strategies for drug developments in Alzheimer's disease. Current Drug Targets. 4: 97-112. PMID 12558063 DOI: 10.2174/1389450033346957  0.44
2003 Eckman EA, Watson M, Marlow L, Sambamurti K, Eckman CB. Alzheimer's disease beta-amyloid peptide is increased in mice deficient in endothelin-converting enzyme. The Journal of Biological Chemistry. 278: 2081-4. PMID 12464614 DOI: 10.1074/jbc.C200642200  0.44
2002 Greig NH, Lahiri DK, Sambamurti K. Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. International Psychogeriatrics / Ipa. 14: 77-91. PMID 12636181 DOI: 10.1017/S1041610203008676  0.44
2002 Lahiri DK, Kotwal GJ, Farlow MR, Sima A, Kupsky W, Sarkar FH, Sambamurti K. The role of the carboxyl-terminal fragments of amyloid precursor protein in Alzheimer's disease. Annals of the New York Academy of Sciences. 973: 334-9. PMID 12485889 DOI: 10.1111/J.1749-6632.2002.Tb04661.X  0.44
2002 Tun H, Marlow L, Pinnix I, Kinsey R, Sambamurti K. Lipid rafts play an important role in A beta biogenesis by regulating the beta-secretase pathway. Journal of Molecular Neuroscience : Mn. 19: 31-5. PMID 12212790 DOI: 10.1007/s12031-002-0007-5  0.44
2002 Sambamurti K, Greig NH, Lahiri DK. Advances in the cellular and molecular biology of the beta-amyloid protein in Alzheimer's disease. Neuromolecular Medicine. 1: 1-31. PMID 12025813 DOI: 10.1385/NMM:1:1:1  0.44
2002 Lahiri DK, Farlow MR, Greig NH, Sambamurti K. Current drug targets for Alzheimer's disease treatment Drug Development Research. 56: 267-281. DOI: 10.1002/Ddr.10081  0.44
2002 Sambamurti K, Hardy J, Refolo LM, Lahiri DK. Targeting APP metabolism for the treatment of Alzheimer's disease Drug Development Research. 56: 211-227. DOI: 10.1002/Ddr.10077  0.44
2001 Mallender WD, Yager D, Onstead L, Nichols MR, Eckman C, Sambamurti K, Kopcho LM, Marcinkeviciene J, Copeland RA, Rosenberry TL. Characterization of recombinant, soluble beta-secretase from an insect cell expression system. Molecular Pharmacology. 59: 619-26. PMID 11179458 DOI: 10.1124/MOL.59.3.619  0.44
2001 Haugabook SJ, Le T, Yager D, Zenk B, Healy BM, Eckman EA, Prada C, Younkin L, Murphy P, Pinnix I, Onstead L, Sambamurti K, Golde TE, Dickson D, Younkin SG, et al. Reduction of Abeta accumulation in the Tg2576 animal model of Alzheimer's disease after oral administration of the phosphatidyl-inositol kinase inhibitor wortmannin. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 16-18. PMID 11099491 DOI: 10.1096/Fj.00-0528Fje  0.44
2000 McLendon C, Xin T, Ziani-Cherif C, Murphy MP, Findlay KA, Lewis PA, Pinnix I, Sambamurti K, Wang R, Fauq A, Golde TE. Cell-free assays for gamma-secretase activity. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 2383-6. PMID 11024004 DOI: 10.1096/Fj.00-0286Fje  0.44
1999 Refolo LM, Eckman C, Prada CM, Yager D, Sambamurti K, Mehta N, Hardy J, Younkin SG. Antisense-induced reduction of presenilin 1 expression selectively increases the production of amyloid beta42 in transfected cells. Journal of Neurochemistry. 73: 2383-8. PMID 10582597 DOI: 10.1046/J.1471-4159.1999.0732383.X  0.44
1999 Sambamurti K, Sevlever D, Koothan T, Refolo LM, Pinnix I, Gandhi S, Onstead L, Younkin L, Prada CM, Yager D, Ohyagi Y, Eckman CB, Rosenberry TL, Younkin SG. Glycosylphosphatidylinositol-anchored proteins play an important role in the biogenesis of the Alzheimer's amyloid beta-protein. The Journal of Biological Chemistry. 274: 26810-4. PMID 10480887 DOI: 10.1074/Jbc.274.38.26810  0.44
1998 Lahiri DK, Farlow MR, Sambamurti K. The secretion of amyloid beta-peptides is inhibited in the tacrine-treated human neuroblastoma cells. Brain Research. Molecular Brain Research. 62: 131-40. PMID 9813282 DOI: 10.1016/S0169-328X(98)00236-8  0.44
1998 Sambamurti K, Lahiri DK. ERAB contains a putative noncleavable signal peptide Biochemical and Biophysical Research Communications. 249: 546-549. PMID 9712734 DOI: 10.1006/bbrc.1998.9178  0.44
1998 Tezapsidis N, Li HC, Ripellino JA, Efthimiopoulos S, Vassilacopoulou D, Sambamurti K, Toneff T, Yasothornsrikul S, Hook VY, Robakis NK. Release of nontransmembrane full-length Alzheimer's amyloid precursor protein from the lumenar surface of chromaffin granule membranes. Biochemistry. 37: 1274-82. PMID 9477953 DOI: 10.1021/Bi9714159  0.44
1997 Lahiri DK, Farlow MR, Sambamurti K, Nall C. The effect of tacrine and leupeptin on the secretion of the beta-amyloid precursor protein in HeLa cells. Life Sciences. 61: 1985-92. PMID 9366505 DOI: 10.1016/S0024-3205(97)00868-0  0.44
1996 Pappolla MA, Sos M, Omar RA, Sambamurti K. The heat shock/oxidative stress connection. Relevance to Alzheimer disease. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 28: 21-34. PMID 8871938 DOI: 10.1007/BF02815201  0.44
1995 Pappolla MA, Sambamurti K, Efthimiopoulos S, Refolo L, Omar RA, Robakis NK. Heat-shock induces abnormalities in the cellular distribution of amyloid precursor protein (APP) and APP fusion proteins. Neuroscience Letters. 192: 105-8. PMID 7675314 DOI: 10.1016/0304-3940(95)11627-9  0.44
1995 Refolo LM, Sambamurti K, Efthimiopoulos S, Pappolla MA, Robakis NK. Evidence that secretase cleavage of cell surface Alzheimer amyloid precursor occurs after normal endocytic internalization. Journal of Neuroscience Research. 40: 694-706. PMID 7602619 DOI: 10.1002/Jnr.490400515  0.44
1994 Efthimiopoulos S, Felsenstein KM, Sambamurti K, Robakis NK, Refolo LM. Study of the phorbol ester effect on Alzheimer amyloid precursor processing: sequence requirements and involvement of a cholera toxin sensitive protein. Journal of Neuroscience Research. 38: 81-90. PMID 8057394 DOI: 10.1002/Jnr.490380111  0.44
1993 Robakis NK, Vassilacopoulou D, Efthimiopoulos S, Sambamurti K, Refolo LM, Shioi J. Cellular processing and proteoglycan nature of amyloid precursor proteins. Annals of the New York Academy of Sciences. 695: 132-8. PMID 8239271 DOI: 10.1111/J.1749-6632.1993.Tb23041.X  0.44
1992 Sambamurti K, Shioi J, Anderson JP, Pappolla MA, Robakis NK. Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells. Journal of Neuroscience Research. 33: 319-29. PMID 1453494 DOI: 10.1002/jnr.490330216  0.44
1992 Sambamurti K, Refolo LM, Shioi J, Pappolla MA, Robakis NK. The Alzheimer's amyloid precursor is cleaved intracellularly in the trans-Golgi network or in a post-Golgi compartment. Annals of the New York Academy of Sciences. 674: 118-28. PMID 1283818 DOI: 10.1111/j.1749-6632.1992.tb27481.x  0.44
1991 Anderson JP, Esch FS, Keim PS, Sambamurti K, Lieberburg I, Robakis NK. Exact cleavage site of Alzheimer amyloid precursor in neuronal PC-12 cells. Neuroscience Letters. 128: 126-8. PMID 1922940 DOI: 10.1016/0304-3940(91)90775-O  0.44
1991 Wallace WC, Bragin V, Robakis NK, Sambamurti K, VanderPutten D, Merril CR, Davis KL, Santucci AC, Haroutunian V. Increased biosynthesis of Alzheimer amyloid precursor protein in the cerebral cortex of rats with lesions of the nucleus basalis of Meynert. Brain Research. Molecular Brain Research. 10: 173-8. PMID 1649369 DOI: 10.1016/0169-328X(91)90108-A  0.44
1990 Robakis NK, Mohamadi M, Fu DY, Sambamurti K, Refolo LM. Human retina D2 receptor cDNAs have multiple polyadenylation sites and differ from a pituitary clone at the 5' non-coding region. Nucleic Acids Research. 18: 1299. PMID 2138729 DOI: 10.1093/Nar/18.5.1299  0.44
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