| Year |
Citation |
Score |
| 2023 |
Rogers JT, Cahill CM. Iron Responsiveness to Lysosomal Disruption: A Novel Pathway to Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 37781810 DOI: 10.3233/JAD-230953 |
0.341 |
|
| 2021 |
Chen XQ, Barrero CA, Vasquez-Del Carpio R, Reddy EP, Fecchio C, Merali S, Deglincerti A, Fang C, Rogers J, Maccecchini ML. Posiphen Reduces the Levels of Huntingtin Protein through Translation Suppression. Pharmaceutics. 13. PMID 34959389 DOI: 10.3390/pharmaceutics13122109 |
0.318 |
|
| 2020 |
Rogers JT, Cahill CM. Iron-responsive-like elements and neurodegenerative ferroptosis. Learning & Memory (Cold Spring Harbor, N.Y.). 27: 395-413. PMID 32817306 DOI: 10.1101/Lm.052282.120 |
0.48 |
|
| 2020 |
Pilozzi A, Yu Z, Carreras I, Cormier K, Hartley D, Rogers J, Dedeoglu A, Huang X. A Preliminary Study of Cu Exposure Effects upon Alzheimer's Amyloid Pathology. Biomolecules. 10. PMID 32155778 DOI: 10.3390/biom10030408 |
0.323 |
|
| 2020 |
Mou X, Pilozzi A, Tailor B, Yi J, Cahill C, Rogers J, Huang X. Exposure to CuO Nanoparticles Mediates NFκB Activation and Enhances Amyloid Precursor Protein Expression. Biomedicines. 8. PMID 32120908 DOI: 10.3390/Biomedicines8030045 |
0.415 |
|
| 2019 |
Kisby B, Jarrell JT, Agar ME, Cohen DS, Rosin ER, Cahill CM, Rogers JT, Huang X. Alzheimer's Disease and Its Potential Alternative Therapeutics. Journal of Alzheimer's Disease & Parkinsonism. 9. PMID 31588368 DOI: 10.4172/2161-0460.1000477 |
0.686 |
|
| 2019 |
Rogers JT, Xia N, Wong A, Bakshi R, Cahill CM. Targeting the Iron-Response Elements of the mRNAs for the Alzheimer's Amyloid Precursor Protein and Ferritin to Treat Acute Lead and Manganese Neurotoxicity. International Journal of Molecular Sciences. 20. PMID 30823541 DOI: 10.3390/Ijms20040994 |
0.488 |
|
| 2019 |
Rogers J, Hodgetts K, Aleyadeh R, Huang X, Cahill C. RNA driven improved iron homeostasis in neurons exposed to parkinsonian manganese stress Journal of Psychology & Psychotherapy. DOI: 10.4172/2161-0487-C4-032 |
0.306 |
|
| 2018 |
Long JM, Maloney B, Rogers JT, Lahiri DK. Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease. Molecular Psychiatry. PMID 30470799 DOI: 10.1038/S41380-018-0266-3 |
0.419 |
|
| 2018 |
Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, ... ... Rogers JT, et al. Manganese causes neurotoxic iron accumulation via translational repression of Amyloid Precursor Protein (APP) and H-Ferritin. Journal of Neurochemistry. PMID 30152072 DOI: 10.1111/Jnc.14580 |
0.427 |
|
| 2018 |
Lumsden AL, Rogers JT, Majd S, Newman M, Sutherland GT, Verdile G, Lardelli M. Dysregulation of Neuronal Iron Homeostasis as an Alternative Unifying Effect of Mutations Causing Familial Alzheimer's Disease. Frontiers in Neuroscience. 12: 533. PMID 30150923 DOI: 10.3389/Fnins.2018.00533 |
0.435 |
|
| 2018 |
Gao J, Cahill CM, Huang X, Roffman JL, Lamon-Fava S, Fava M, Mischoulon D, Rogers JT. S-Adenosyl Methionine and Transmethylation Pathways in Neuropsychiatric Diseases Throughout Life. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. PMID 29340929 DOI: 10.1007/S13311-017-0593-0 |
0.323 |
|
| 2017 |
Yin X, Wu Q, Monga J, Xie E, Wang H, Wang S, Zhang H, Wang ZY, Zhou T, Shi Y, Rogers J, Lin H, Min J, Wang F. HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-overload Murine Models. Antioxidants & Redox Signaling. PMID 29113455 DOI: 10.1089/Ars.2017.7161 |
0.349 |
|
| 2017 |
Meng T, Cao Q, Lei P, Bush AI, Xiang Q, Su Z, He X, Rogers JT, Chiu IM, Zhang Q, Huang Y. Tat-haFGF14-154 Upregulates ADAM10 to Attenuate the Alzheimer Phenotype of APP/PS1 Mice through the PI3K-CREB-IRE1α/XBP1 Pathway. Molecular Therapy. Nucleic Acids. 7: 439-452. PMID 28624220 DOI: 10.1016/J.Omtn.2017.05.004 |
0.412 |
|
| 2016 |
Rogers JT, Venkataramani V, Washburn C, Liu Y, Tummala V, Jiang H, Smith A, Cahill CM. A Role for Amyloid Precursor Protein Translation to Restore Iron Homeostasis and Ameliorate Lead (Pb) Neurotoxicity. Journal of Neurochemistry. PMID 27206843 DOI: 10.1111/Jnc.13671 |
0.44 |
|
| 2016 |
Plascencia-Villa G, Ponce A, Collingwood JF, Arellano-Jiménez MJ, Zhu X, Rogers JT, Betancourt I, José-Yacamán M, Perry G. High-resolution analytical imaging and electron holography of magnetite particles in amyloid cores of Alzheimer's disease. Scientific Reports. 6: 24873. PMID 27121137 DOI: 10.1038/Srep24873 |
0.358 |
|
| 2016 |
Jiang H, Wang J, Rogers J, Xie J. Brain Iron Metabolism Dysfunction in Parkinson's Disease. Molecular Neurobiology. PMID 27039308 DOI: 10.1007/S12035-016-9879-1 |
0.399 |
|
| 2016 |
A. Lu M, Rajanala S, Mikkilineni SV, Cahill CM, Brown R, D. Berry J, Rogers JT. The 5’-Untranslated Region of the C9orf72 mRNA Exhibits a Phylogenetic Alignment to the Cis-Aconitase Iron-Responsive Element; Novel Therapies for Amytrophic Lateral Sclerosis Neuroscience and Medicine. 7: 15-26. DOI: 10.4236/Nm.2016.71003 |
0.35 |
|
| 2015 |
Ayton S, Lei P, Hare DJ, Duce JA, George JL, Adlard PA, McLean C, Rogers JT, Cherny RA, Finkelstein DI, Bush AI. Parkinson's disease iron deposition caused by nitric oxide-induced loss of β-amyloid precursor protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 3591-7. PMID 25716857 DOI: 10.1523/Jneurosci.3439-14.2015 |
0.409 |
|
| 2014 |
Tao Y, Wang Y, Rogers JT, Wang F. Perturbed iron distribution in Alzheimer's disease serum, cerebrospinal fluid, and selected brain regions: a systematic review and meta-analysis. Journal of Alzheimer's Disease : Jad. 42: 679-90. PMID 24916541 DOI: 10.3233/Jad-140396 |
0.454 |
|
| 2014 |
Bandyopadhyay S, Rogers JT. Alzheimer's disease therapeutics targeted to the control of amyloid precursor protein translation: maintenance of brain iron homeostasis. Biochemical Pharmacology. 88: 486-94. PMID 24513321 DOI: 10.1016/J.Bcp.2014.01.032 |
0.519 |
|
| 2013 |
Bandyopadhyay S, Cahill C, Balleidier A, Huang C, Lahiri DK, Huang X, Rogers JT. Novel 5' untranslated region directed blockers of iron-regulatory protein-1 dependent amyloid precursor protein translation: implications for down syndrome and Alzheimer's disease. Plos One. 8: e65978. PMID 23935819 DOI: 10.1371/Journal.Pone.0065978 |
0.493 |
|
| 2013 |
Lahiri DK, Maloney B, Rogers JT, Ge YW. PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE). Bmc Genomics. 14: 68. PMID 23368879 DOI: 10.1186/1471-2164-14-68 |
0.47 |
|
| 2013 |
Yu QS, Reale M, Kamal MA, Holloway HW, Luo W, Sambamurti K, Ray B, Lahiri DK, Rogers JT, Greig NH. Synthesis of the Alzheimer drug Posiphen into its primary metabolic products (+)-N1-norPosiphen, (+)-N8-norPosiphen and (+)-N1, N8-bisnorPosiphen, their inhibition of amyloid precursor protein, α-Synuclein synthesis, interleukin-1β release, and cholinergic action. Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistry. 12: 117-28. PMID 23360256 DOI: 10.2174/1871523011312020003 |
0.412 |
|
| 2013 |
Hahl P, Davis T, Washburn C, Rogers JT, Smith A. Mechanisms of neuroprotection by hemopexin: modeling the control of heme and iron homeostasis in brain neurons in inflammatory states. Journal of Neurochemistry. 125: 89-101. PMID 23350672 DOI: 10.1111/Jnc.12165 |
0.365 |
|
| 2013 |
Duce JA, Ayton S, Miller AA, Tsatsanis A, Lam LQ, Leone L, Corbin JE, Butzkueven H, Kilpatrick TJ, Rogers JT, Barnham KJ, Finkelstein DI, Bush AI. Amine oxidase activity of β-amyloid precursor protein modulates systemic and local catecholamine levels. Molecular Psychiatry. 18: 245-54. PMID 22212595 DOI: 10.1038/Mp.2011.168 |
0.358 |
|
| 2013 |
Rogers J, Spoonamore J. Novel untranslated region-directed blockers of amyloid precursor protein translation for late Down syndrome and Alzheimer's disease therapy Alzheimers & Dementia. 9: 855. DOI: 10.1016/J.Jalz.2013.08.170 |
0.41 |
|
| 2012 |
Mikkilineni S, Cantuti-Castelvetri I, Cahill CM, Balliedier A, Greig NH, Rogers JT. The anticholinesterase phenserine and its enantiomer posiphen as 5'untranslated-region-directed translation blockers of the Parkinson's alpha synuclein expression. Parkinson's Disease. 2012: 142372. PMID 22693681 DOI: 10.1155/2012/142372 |
0.36 |
|
| 2012 |
Olivares D, Deshpande VK, Shi Y, Lahiri DK, Greig NH, Rogers JT, Huang X. N-methyl D-aspartate (NMDA) receptor antagonists and memantine treatment for Alzheimer's disease, vascular dementia and Parkinson's disease. Current Alzheimer Research. 9: 746-58. PMID 21875407 DOI: 10.2174/156720512801322564 |
0.373 |
|
| 2012 |
Rogers J, Kolar J, Washburn C, Cahill C, Huang X. Therapeutic action of translation blockers on expression of the amyloid precursor protein as a central ferroxidase Alzheimers & Dementia. 8: 714. DOI: 10.1016/J.Jalz.2012.05.1930 |
0.382 |
|
| 2011 |
Rogers JT, Mikkilineni S, Cantuti-Castelvetri I, Smith DH, Huang X, Bandyopadhyay S, Cahill CM, Maccecchini ML, Lahiri DK, Greig NH. The alpha-synuclein 5'untranslated region targeted translation blockers: anti-alpha synuclein efficacy of cardiac glycosides and Posiphen. Journal of Neural Transmission (Vienna, Austria : 1996). 118: 493-507. PMID 21221670 DOI: 10.1007/S00702-010-0513-5 |
0.369 |
|
| 2011 |
Duce J, Lei P, Tsatsanis A, Ayton S, Lam L, Adlard P, Ciccotosto G, Masters C, Cappai R, Barnham K, Rogers J, Finkelstein D, Bush A. The relationship between beta-amyloid protein precursor and tau in Alzheimer's disease-related iron disruption Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1422 |
0.468 |
|
| 2010 |
Bandyopadhyay S, Huang X, Lahiri DK, Rogers JT. Novel drug targets based on metallobiology of Alzheimer's disease. Expert Opinion On Therapeutic Targets. 14: 1177-97. PMID 20942746 DOI: 10.1517/14728222.2010.525352 |
0.468 |
|
| 2010 |
Duce JA, Tsatsanis A, Cater MA, James SA, Robb E, Wikhe K, Leong SL, Perez K, Johanssen T, Greenough MA, Cho HH, Galatis D, Moir RD, Masters CL, McLean C, ... ... Rogers JT, et al. Iron-export ferroxidase activity of β-amyloid precursor protein is inhibited by zinc in Alzheimer's disease. Cell. 142: 857-67. PMID 20817278 DOI: 10.1016/J.Cell.2010.08.014 |
0.482 |
|
| 2010 |
Cho HH, Cahill CM, Vanderburg CR, Scherzer CR, Wang B, Huang X, Rogers JT. Selective translational control of the Alzheimer amyloid precursor protein transcript by iron regulatory protein-1. The Journal of Biological Chemistry. 285: 31217-32. PMID 20558735 DOI: 10.1074/Jbc.M110.149161 |
0.414 |
|
| 2010 |
Maloney B, Ge YW, Petersen RC, Hardy J, Rogers JT, Pérez-Tur J, Lahiri DK. Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 153: 185-201. PMID 19504470 DOI: 10.1002/Ajmg.B.30973 |
0.357 |
|
| 2010 |
Goldstein LE, Moir RD, Mocofanescu A, Fu L, Lu S, Burton MA, Xu W, Ericsson M, Rogers J, Chadwick O, Sadowski M, Wisniewski T, Klunk WE, Mathis CA, Clark JI, et al. P4-011: In vivo Detection of Early Alzheimer's Disease-Linked Aβ Peptide Accumulation in the Lens by Non-Invasive Quasi-Elastic Light Scattering Alzheimer's & Dementia. 6: e23-e23. DOI: 10.1016/J.Jalz.2010.08.071 |
0.352 |
|
| 2009 |
Olivares D, Huang X, Branden L, Greig NH, Rogers JT. Physiological and pathological role of alpha-synuclein in Parkinson's disease through iron mediated oxidative stress; the role of a putative iron-responsive element. International Journal of Molecular Sciences. 10: 1226-60. PMID 19399246 DOI: 10.3390/Ijms10031226 |
0.396 |
|
| 2009 |
Kong W, Mou X, Liu Q, Chen Z, Vanderburg CR, Rogers JT, Huang X. Independent component analysis of Alzheimer's DNA microarray gene expression data. Molecular Neurodegeneration. 4: 5. PMID 19173745 DOI: 10.1186/1750-1326-4-5 |
0.347 |
|
| 2009 |
Cahill CM, Lahiri DK, Huang X, Rogers JT. Amyloid precursor protein and alpha synuclein translation, implications for iron and inflammation in neurodegenerative diseases. Biochimica Et Biophysica Acta. 1790: 615-28. PMID 19166904 DOI: 10.1016/J.Bbagen.2008.12.001 |
0.496 |
|
| 2009 |
Lahiri DK, Maloney B, Ray B, Rogers JT, Zawia N. S4-03-03: The “LEARn” (Latent Early-life Associated Regulation) model may explain the etiology of sporadic cases of Alzheimer's disease Alzheimer's & Dementia. 5: P146-P146. DOI: 10.1016/J.Jalz.2009.05.501 |
0.349 |
|
| 2009 |
Rogers JT, Huang X, Goldstein LE, Moncaster JA, Lahiri DK, Cahill CM, Cho H, Fischer M, Glicksman MA, Cuny GD, Rogers MS, Greig NH, Smith DH, Branden LJ. Specific APP translation blockers as a therapeutic intervention for Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.470 |
0.396 |
|
| 2008 |
Rogers JT, Bush AI, Cho HH, Smith DH, Thomson AM, Friedlich AL, Lahiri DK, Leedman PJ, Huang X, Cahill CM. Iron and the translation of the amyloid precursor protein (APP) and ferritin mRNAs: riboregulation against neural oxidative damage in Alzheimer's disease. Biochemical Society Transactions. 36: 1282-7. PMID 19021541 DOI: 10.1042/Bst0361282 |
0.489 |
|
| 2008 |
Patel N, Hoang D, Miller N, Ansaloni S, Huang Q, Rogers JT, Lee JC, Saunders AJ. MicroRNAs can regulate human APP levels. Molecular Neurodegeneration. 3: 10. PMID 18684319 DOI: 10.1186/1750-1326-3-10 |
0.355 |
|
| 2008 |
Moncaster JA, Moir RD, Mocofanescu AG, Burton MA, Ghosh J, Ericsson M, Rogers JT, Klunk WE, Mathis CA, Sadowski M, Wisniewski T, Clark JI, Tanzi RE, Goldstein LE. P1-379: In vivo detection of Alzheimer's disease–linked Aβ peptide accumulation in the lens Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.961 |
0.355 |
|
| 2008 |
Duce JA, Rogers JT, Tsatsanis A, Moir RD, Robb E, Leong SL, Harding SM, Venti A, Masters C, Cappai R, Tanzi RE, Bush AI. P3-325: Alzheimer's disease β-amyloid protein precursor is ferroxidase II, a ceruloplasmin-like iron detoxification enzyme Alzheimer's & Dementia. 4: T617-T617. DOI: 10.1016/J.Jalz.2008.05.1894 |
0.425 |
|
| 2007 |
Bandyopadhyay S, Goldstein LE, Lahiri DK, Rogers JT. Role of the APP non-amyloidogenic signaling pathway and targeting alpha-secretase as an alternative drug target for treatment of Alzheimer's disease. Current Medicinal Chemistry. 14: 2848-64. PMID 18045131 DOI: 10.2174/092986707782360060 |
0.347 |
|
| 2007 |
Friedlich AL, Tanzi RE, Rogers JT. The 5'-untranslated region of Parkinson's disease alpha-synuclein messengerRNA contains a predicted iron responsive element. Molecular Psychiatry. 12: 222-3. PMID 17325711 DOI: 10.1038/Sj.Mp.4001937 |
0.364 |
|
| 2007 |
Moncaster J, Moir RD, Fu L, Mocofanescu A, Lu S, Xu W, Chadwick O, Rogers JT, Sadowski M, Wisniewski T, Klunk WE, Mathis CA, Clark JI, Tanzi RE, Goldstein LE. O2-03-05: Early detection of Alzheimer's disease-linked aβ peptide accumulation in the lens by non-invasive quasi-elastic light scattering Alzheimer's & Dementia. 3: S190-S190. DOI: 10.1016/J.Jalz.2007.04.030 |
0.347 |
|
| 2006 |
Bandyopadhyay S, Huang X, Cho H, Greig NH, Youdim MB, Rogers JT. Metal specificity of an iron-responsive element in Alzheimer's APP mRNA 5'untranslated region, tolerance of SH-SY5Y and H4 neural cells to desferrioxamine, clioquinol, VK-28, and a piperazine chelator. Journal of Neural Transmission. Supplementum. 237-47. PMID 17447434 DOI: 10.1007/978-3-211-33328-0_25 |
0.417 |
|
| 2006 |
Lahiri DK, Ge YW, Rogers JT, Sambamurti K, Greig NH, Maloney B. Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors. Current Alzheimer Research. 3: 475-83. PMID 17168646 DOI: 10.2174/156720506779025224 |
0.402 |
|
| 2006 |
Bandyopadhyay S, Ni J, Ruggiero A, Walshe K, Rogers MS, Chattopadhyay N, Glicksman MA, Rogers JT. A high-throughput drug screen targeted to the 5'untranslated region of Alzheimer amyloid precursor protein mRNA. Journal of Biomolecular Screening. 11: 469-80. PMID 16928984 DOI: 10.1177/1087057106287271 |
0.44 |
|
| 2006 |
Tucker S, Ahl M, Cho HH, Bandyopadhyay S, Cuny GD, Bush AI, Goldstein LE, Westaway D, Huang X, Rogers JT. RNA therapeutics directed to the non coding regions of APP mRNA, in vivo anti-amyloid efficacy of paroxetine, erythromycin, and N-acetyl cysteine. Current Alzheimer Research. 3: 221-7. PMID 16842099 DOI: 10.2174/156720506777632835 |
0.426 |
|
| 2006 |
Liu G, Huang W, Moir RD, Vanderburg CR, Lai B, Peng Z, Tanzi RE, Rogers JT, Huang X. Metal exposure and Alzheimer's pathogenesis. Journal of Structural Biology. 155: 45-51. PMID 16503166 DOI: 10.1016/J.Jsb.2005.12.011 |
0.447 |
|
| 2005 |
Tucker S, Ahl M, Bush A, Westaway D, Huang X, Rogers JT. Pilot study of the reducing effect on amyloidosis in vivo by three FDA pre-approved drugs via the Alzheimer's APP 5' untranslated region. Current Alzheimer Research. 2: 249-54. PMID 15974925 DOI: 10.2174/1567205053585855 |
0.412 |
|
| 2005 |
Thomson AM, Cahill CM, Cho HH, Kassachau KD, Epis MR, Bridges KR, Leedman PJ, Rogers JT. The acute box cis-element in human heavy ferritin mRNA 5'-untranslated region is a unique translation enhancer that binds poly(C)-binding proteins. The Journal of Biological Chemistry. 280: 30032-45. PMID 15967798 DOI: 10.1074/Jbc.M502951200 |
0.369 |
|
| 2005 |
Rogers JT, Bandyopadhyay S, Tucker S, Huang X, Gullans S. Alzheimer’s disease drug discovery targeted to the APP mRNA 5′ untranslated region, paroxetine proof-of-concept for a validated target Alzheimers & Dementia. 1. DOI: 10.1016/J.Jalz.2005.06.257 |
0.343 |
|
| 2004 |
Greig NH, Mattson MP, Perry T, Chan SL, Giordano T, Sambamurti K, Rogers JT, Ovadia H, Lahiri DK. New therapeutic strategies and drug candidates for neurodegenerative diseases: p53 and TNF-alpha inhibitors, and GLP-1 receptor agonists. Annals of the New York Academy of Sciences. 1035: 290-315. PMID 15681814 DOI: 10.1196/Annals.1332.018 |
0.396 |
|
| 2004 |
Lahiri DK, Chen D, Lahiri P, Rogers JT, Greig NH, Bondy S. Melatonin, metals, and gene expression: implications in aging and neurodegenerative disorders. Annals of the New York Academy of Sciences. 1035: 216-30. PMID 15681810 DOI: 10.1196/Annals.1332.014 |
0.37 |
|
| 2004 |
Venti A, Giordano T, Eder P, Bush AI, Lahiri DK, Greig NH, Rogers JT. The integrated role of desferrioxamine and phenserine targeted to an iron-responsive element in the APP-mRNA 5'-untranslated region. Annals of the New York Academy of Sciences. 1035: 34-48. PMID 15681799 DOI: 10.1196/Annals.1332.003 |
0.482 |
|
| 2004 |
Dedeoglu A, Cormier K, Payton S, Tseitlin KA, Kremsky JN, Lai L, Li X, Moir RD, Tanzi RE, Bush AI, Kowall NW, Rogers JT, Huang X. Preliminary studies of a novel bifunctional metal chelator targeting Alzheimer's amyloidogenesis. Experimental Gerontology. 39: 1641-9. PMID 15582280 DOI: 10.1016/J.Exger.2004.08.016 |
0.439 |
|
| 2004 |
Lahiri DK, Rogers JT, Greig NH, Sambamurti K. Rationale for the development of cholinesterase inhibitors as anti-Alzheimer agents. Current Pharmaceutical Design. 10: 3111-9. PMID 15544501 DOI: 10.2174/1381612043383331 |
0.435 |
|
| 2004 |
Morse LJ, Payton SM, Cuny GD, Rogers JT. FDA-preapproved drugs targeted to the translational regulation and processing of the amyloid precursor protein. Journal of Molecular Neuroscience : Mn. 24: 129-36. PMID 15314261 DOI: 10.1385/Jmn:24:1:129 |
0.462 |
|
| 2004 |
Rogers JT, Lahiri DK. Metal and inflammatory targets for Alzheimer's disease. Current Drug Targets. 5: 535-51. PMID 15270200 DOI: 10.2174/1389450043345272 |
0.502 |
|
| 2004 |
Huang X, Moir RD, Tanzi RE, Bush AI, Rogers JT. Redox-active metals, oxidative stress, and Alzheimer's disease pathology. Annals of the New York Academy of Sciences. 1012: 153-63. PMID 15105262 DOI: 10.1196/Annals.1306.012 |
0.454 |
|
| 2004 |
Rogers JT, Payton S, Greig NH, Jensen R, Cuny G, Lahiri DK, Morse LJ, Tanzi RE, Westaway D, Bush A, Gullans S, Sarang S, Huang X. P4-402 Alzheimer's disease drug discovery targeted to the APP MRNA 5′ untranslated region, a validated target Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81959-6 |
0.391 |
|
| 2004 |
Rogers JT, Morse LJ, Lombardi M, Devaney P, Jensen R. P4-245 Metallothionein 3 gene expression is up-regulated by intracellular iron chelation, the role of a putative iron-responsive element in the 3′ untranslated region Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81803-7 |
0.353 |
|
| 2004 |
Greig NH, Utsuki T, Wang Y, Ingram DK, Mamczar J, Rogers J, Yun Q, Holloway HW, Perry TA, Sambamurti K, Scali C, Pepeu G, Lahiri DK. P1-414 Selective butyrylcholinesterase inhibition elevates brain acetylcholine, augments learning and lowers amyloid-beta peptide in rodents: a new treatment strategy for Alzheimer's disease Neurobiology of Aging. 25: S216. DOI: 10.1016/S0197-4580(04)80726-7 |
0.366 |
|
| 2003 |
Payton S, Cahill CM, Randall JD, Gullans SR, Rogers JT. Drug discovery targeted to the Alzheimer's APP mRNA 5'-untranslated region: the action of paroxetine and dimercaptopropanol. Journal of Molecular Neuroscience : Mn. 20: 267-75. PMID 14501007 DOI: 10.1385/Jmn:20:3:267 |
0.411 |
|
| 2003 |
Lahiri DK, Chen D, Vivien D, Ge YW, Greig NH, Rogers JT. Role of cytokines in the gene expression of amyloid beta-protein precursor: identification of a 5'-UTR-binding nuclear factor and its implications in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 5: 81-90. PMID 12719626 DOI: 10.3233/Jad-2003-5203 |
0.408 |
|
| 2002 |
Rogers JT, Randall JD, Eder PS, Huang X, Bush AI, Tanzi RE, Venti A, Payton SM, Giordano T, Nagano S, Cahill CM, Moir R, Lahiri DK, Greig N, Sarang SS, et al. Alzheimer's disease drug discovery targeted to the APP mRNA 5'untranslated region. Journal of Molecular Neuroscience : Mn. 19: 77-82. PMID 12212798 DOI: 10.1007/S12031-002-0014-6 |
0.431 |
|
| 2002 |
Rogers JT, Randall JD, Cahill CM, Eder PS, Huang X, Gunshin H, Leiter L, McPhee J, Sarang SS, Utsuki T, Greig NH, Lahiri DK, Tanzi RE, Bush AI, Giordano T, et al. An iron-responsive element type II in the 5'-untranslated region of the Alzheimer's amyloid precursor protein transcript. The Journal of Biological Chemistry. 277: 45518-28. PMID 12198135 DOI: 10.1074/Jbc.M207435200 |
0.46 |
|
| 2001 |
Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze MW, Rouault TA, Andrews NC, Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. Febs Letters. 509: 309-16. PMID 11741608 DOI: 10.1016/S0014-5793(01)03189-1 |
0.374 |
|
| 2001 |
Shaw KT, Utsuki T, Rogers J, Yu QS, Sambamurti K, Brossi A, Ge YW, Lahiri DK, Greig NH. Phenserine regulates translation of beta -amyloid precursor protein mRNA by a putative interleukin-1 responsive element, a target for drug development. Proceedings of the National Academy of Sciences of the United States of America. 98: 7605-10. PMID 11404470 DOI: 10.1073/Pnas.131152998 |
0.454 |
|
| 2000 |
Bush AI, Atwood CS, Goldstein LE, Huang X, Rogers J. Could Abeta and AbetaPP be Antioxidants? Journal of Alzheimer's Disease : Jad. 2: 83-84. PMID 12214093 DOI: 10.3233/Jad-2000-2203 |
0.314 |
|
| 2000 |
Thomson AM, Rogers JT, Leedman PJ. Thyrotropin-releasing hormone and epidermal growth factor regulate iron-regulatory protein binding in pituitary cells via protein kinase C-dependent and -independent signaling pathways. The Journal of Biological Chemistry. 275: 31609-15. PMID 10889193 DOI: 10.1074/Jbc.M002354200 |
0.336 |
|
| 2000 |
Rogers JT, Moir RD, Huang X, Venti A, Sarhan N, Nostrand WEV, Tanzi R. Intrinsic ferroxidase activity in the Alzheimer's amyloid precursor protein Neurobiology of Aging. 21: 261. DOI: 10.1016/S0197-4580(00)83126-7 |
0.419 |
|
| 1999 |
Thomson AM, Rogers JT, Leedman PJ. Iron-regulatory proteins, iron-responsive elements and ferritin mRNA translation. The International Journal of Biochemistry & Cell Biology. 31: 1139-52. PMID 10582343 DOI: 10.1016/S1357-2725(99)00080-1 |
0.384 |
|
| 1999 |
Rogers JT, Leiter LM, McPhee J, Cahill CM, Zhan SS, Potter H, Nilsson LN. Translation of the alzheimer amyloid precursor protein mRNA is up-regulated by interleukin-1 through 5'-untranslated region sequences. The Journal of Biological Chemistry. 274: 6421-31. PMID 10037734 DOI: 10.1074/Jbc.274.10.6421 |
0.425 |
|
| 1999 |
Toth I, Yuan L, Rogers JT, Boyce H, Bridges KR. Hypoxia alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in human hepatoma and erythroleukemia cells. The Journal of Biological Chemistry. 274: 4467-73. PMID 9933651 DOI: 10.1074/Jbc.274.7.4467 |
0.376 |
|
| 1996 |
Leedman PJ, Stein AR, Chin WW, Rogers JT. Thyroid hormone modulates the interaction between iron regulatory proteins and the ferritin mRNA iron-responsive element. The Journal of Biological Chemistry. 271: 12017-23. PMID 8662626 DOI: 10.1074/Jbc.271.20.12017 |
0.345 |
|
| 1995 |
Toth I, Rogers JT, McPhee JA, Elliott SM, Abramson SL, Bridges KR. Ascorbic acid enhances iron-induced ferritin translation in human leukemia and hepatoma cells. The Journal of Biological Chemistry. 270: 2846-52. PMID 7852359 DOI: 10.1074/Jbc.270.6.2846 |
0.386 |
|
| 1994 |
Rogers JT, Andriotakis JL, Lacroix L, Durmowicz GP, Kasschau KD, Bridges KR. Translational enhancement of H-ferritin mRNA by interleukin-1 beta acts through 5' leader sequences distinct from the iron responsive element. Nucleic Acids Research. 22: 2678-86. PMID 8041631 DOI: 10.1093/Nar/22.13.2678 |
0.325 |
|
| 1994 |
Rogers J, Lacroix L, Durmowitz G, Kasschau K, Andriotakis J, Bridges KR. The role of cytokines in the regulation of ferritin expression. Advances in Experimental Medicine and Biology. 356: 127-132. PMID 7534028 DOI: 10.1007/978-1-4615-2554-7_14 |
0.332 |
|
| 1993 |
Steel DM, Rogers JT, DeBeer MC, DeBeer FC, Whitehead AS. Biosynthesis of human acute-phase serum amyloid A protein (A-SAA) in vitro: the roles of mRNA accumulation, poly(A) tail shortening and translational efficiency. The Biochemical Journal. 291: 701-7. PMID 8387777 DOI: 10.1042/Bj2910701 |
0.312 |
|
| 1987 |
Rogers J, Munro H. Translation of ferritin light and heavy subunit mRNAs is regulated by intracellular chelatable iron levels in rat hepatoma cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 2277-81. PMID 3470792 DOI: 10.1073/Pnas.84.8.2277 |
0.39 |
|
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