| Year |
Citation |
Score |
| 2024 |
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Willey S, Van Deynze K, Mumm C, Boyle AP, Cortese A, Ndayisaba A, Khurana V, Barmada SJ, ... ... Todd PK, et al. AAGGG repeat expansions trigger -independent synaptic dysregulation in human CANVAS neurons. Science Advances. 10: eadn2321. PMID 39231235 DOI: 10.1126/sciadv.adn2321 |
0.348 |
|
| 2024 |
Dykstra MM, Weskamp K, Gómez NB, Waksmacki J, Tank E, Glineburg MR, Snyder A, Pinarbasi E, Bekier M, Li X, Bai J, Shahzad S, Nedumaran J, Wieland C, Stewart C, ... ... Todd P, et al. TDP43 autoregulation gives rise to shortened isoforms that are tightly controlled by both transcriptional and post-translational mechanisms. Biorxiv : the Preprint Server For Biology. PMID 39005384 DOI: 10.1101/2024.07.02.601776 |
0.369 |
|
| 2024 |
Tseng YJ, Krans A, Malik I, Deng X, Yildirim E, Ovunc S, Tank EMH, Jansen-West K, Kaufhold R, Gomez NB, Sher R, Petrucelli L, Barmada SJ, Todd PK. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats. Nucleic Acids Research. PMID 38412259 DOI: 10.1093/nar/gkae137 |
0.469 |
|
| 2023 |
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Khurana V, Barmada SJ, Dijkstra AA, Todd PK. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. Biorxiv : the Preprint Server For Biology. PMID 38168171 DOI: 10.1101/2023.12.13.571345 |
0.321 |
|
| 2023 |
Tassone F, Protic D, Allen EG, Archibald AD, Baud A, Brown TW, Budimirovic DB, Cohen J, Dufour B, Eiges R, Elvassore N, Gabis LV, Grudzien SJ, Hall DA, Hessl D, ... ... Todd PK, et al. Insight and Recommendations for Fragile X-Premutation-Associated Conditions from the Fifth International Conference on Premutation. Cells. 12. PMID 37759552 DOI: 10.3390/cells12182330 |
0.431 |
|
| 2023 |
Malik I, Tseng YJ, Wieland C, Green KM, Zheng K, Calleja K, Todd PK. Dissecting the roles of EIF4G homologs reveals DAP5 as a modifier of CGG repeat-associated toxicity in a Drosophila model of FXTAS. Neurobiology of Disease. 106212. PMID 37352983 DOI: 10.1016/j.nbd.2023.106212 |
0.471 |
|
| 2023 |
Tseng YJ, Malik I, Deng X, Krans A, Jansen-West K, Tank EMH, Gomez NB, Sher R, Petrucelli L, Barmada SJ, Todd PK. Ribosomal quality control factors inhibit repeat-associated non-AUG translation from GC-rich repeats. Biorxiv : the Preprint Server For Biology. PMID 37333274 DOI: 10.1101/2023.06.07.544135 |
0.468 |
|
| 2023 |
Wright SE, Todd PK. Native functions of short tandem repeats. Elife. 12. PMID 36940239 DOI: 10.7554/eLife.84043 |
0.609 |
|
| 2023 |
Wang ET, Freudenreich CH, Gromak N, Jain A, Todd PK, Nagai Y. What repeat expansion disorders can teach us about the Central Dogma. Molecular Cell. 83: 324-329. PMID 36736306 DOI: 10.1016/j.molcel.2022.12.017 |
0.328 |
|
| 2022 |
Reyes CJ, Asano K, Todd PK, Klein C, Rakovic A. Repeat-Associated Non-AUG Translation of AGAGGG Repeats that Cause X-Linked Dystonia-Parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35971992 DOI: 10.1002/mds.29183 |
0.357 |
|
| 2022 |
Wright SE, Rodriguez CM, Monroe J, Xing J, Krans A, Flores BN, Barsur V, Ivanova MI, Koutmou KS, Barmada SJ, Todd PK. CGG repeats trigger translational frameshifts that generate aggregation-prone chimeric proteins. Nucleic Acids Research. PMID 35904811 DOI: 10.1093/nar/gkac626 |
0.806 |
|
| 2022 |
Kong HE, Lim J, Linsalata A, Kang Y, Malik I, Allen EG, Cao Y, Shubeck L, Johnston R, Huang Y, Gu Y, Guo X, Zwick ME, Qin Z, Wingo TS, ... ... Todd PK, et al. Identification of as a genetic modifier of fragile X-associated tremor/ataxia syndrome. Proceedings of the National Academy of Sciences of the United States of America. 119: e2118124119. PMID 35617426 DOI: 10.1073/pnas.2118124119 |
0.333 |
|
| 2022 |
Green KM, Miller SL, Malik I, Todd PK. Non-canonical initiation factors modulate repeat-associated non-AUG translation. Human Molecular Genetics. PMID 35220421 DOI: 10.1093/hmg/ddac021 |
0.408 |
|
| 2022 |
Zhang Y, Glineburg MR, Basrur V, Conlon K, Wright SE, Krans A, Hall DA, Todd PK. Mechanistic convergence across initiation sites for RAN translation in fragile X associated tremor ataxia syndrome. Human Molecular Genetics. PMID 35137065 DOI: 10.1093/hmg/ddab353 |
0.677 |
|
| 2021 |
Malik I, Tseng YJ, Wright SE, Zheng K, Ramaiyer P, Green KM, Todd PK. SRSF protein kinase 1 modulates RAN translation and suppresses CGG repeat toxicity. Embo Molecular Medicine. e14163. PMID 34542927 DOI: 10.15252/emmm.202114163 |
0.715 |
|
| 2021 |
Singh CR, Glineburg MR, Moore C, Tani N, Jaiswal R, Zou Y, Aube E, Gillaspie S, Thornton M, Cecil A, Hilgers M, Takasu A, Asano I, Asano M, Escalante CR, ... ... Todd PK, et al. Human oncoprotein 5MP suppresses general and repeat-associated non-AUG translation via eIF3 by a common mechanism. Cell Reports. 36: 109376. PMID 34260931 DOI: 10.1016/j.celrep.2021.109376 |
0.456 |
|
| 2021 |
Tseng YJ, Sandwith SN, Green KM, Chambers AE, Krans A, Raimer HM, Sharlow ME, Reisinger MA, Richardson AE, Routh ED, Smaldino MA, Wang YH, Vaughn JP, Todd PK, Smaldino PJ. The RNA helicase DHX36/G4R1 modulates C9orf72 GGGGCC hexanucleotide repeat- associated translation. The Journal of Biological Chemistry. 100914. PMID 34174288 DOI: 10.1016/j.jbc.2021.100914 |
0.453 |
|
| 2021 |
Malik I, Kelley CP, Wang ET, Todd PK. Molecular mechanisms underlying nucleotide repeat expansion disorders. Nature Reviews. Molecular Cell Biology. PMID 34140671 DOI: 10.1038/s41580-021-00382-6 |
0.369 |
|
| 2021 |
Glineburg MR, Zhang Y, Krans A, Tank EM, Barmada SJ, Todd PK. Enhanced detection of expanded repeat mRNA foci with hybridization chain reaction. Acta Neuropathologica Communications. 9: 73. PMID 33892814 DOI: 10.1186/s40478-021-01169-8 |
0.317 |
|
| 2021 |
Dijkstra AA, Haify SN, Verwey NA, Prins ND, van der Toorn EC, Rozemuller AJM, Bugiani M, den Dunnen WFA, Todd PK, Charlet-Berguerand N, Willemsen R, Hukema RK, Hoozemans JJM. Neuropathology of -premutation carriers presenting with dementia and neuropsychiatric symptoms. Brain Communications. 3: fcab007. PMID 33709078 DOI: 10.1093/braincomms/fcab007 |
0.336 |
|
| 2020 |
Skariah G, Todd PK. Translational control in aging and neurodegeneration. Wiley Interdisciplinary Reviews. Rna. e1628. PMID 32954679 DOI: 10.1002/Wrna.1628 |
0.785 |
|
| 2020 |
He F, Flores BN, Krans A, Frazer M, Natla S, Niraula S, Adefioye O, Barmada SJ, Todd PK. The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD. Acta Neuropathologica Communications. 8: 122. PMID 32753055 DOI: 10.1186/S40478-020-01002-8 |
0.614 |
|
| 2020 |
Rodriguez CM, Wright SE, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans A, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, ... Todd PK, et al. A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis. Nature Neuroscience. PMID 32066985 DOI: 10.1038/S41593-020-0590-1 |
0.799 |
|
| 2019 |
Krans A, Skariah G, Zhang Y, Bayly B, Todd PK. Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome. Acta Neuropathologica Communications. 7: 152. PMID 31665086 DOI: 10.1186/S40478-019-0782-7 |
0.818 |
|
| 2019 |
Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT. Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology. Acta Neuropathologica Communications. 7: 158. PMID 31665069 DOI: 10.1186/S40478-019-0818-Z |
0.311 |
|
| 2019 |
Green KM, Sheth U, Flores BN, Wright SE, Sutter A, Kearse MG, Barmada S, Ivanova MI, Todd PK. High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation. The Journal of Biological Chemistry. PMID 31649034 DOI: 10.1074/Jbc.Ra119.009951 |
0.831 |
|
| 2019 |
Linsalata AE, He F, Malik AM, Glineburg MR, Green KM, Natla S, Flores BN, Krans A, Archbold HC, Fedak SJ, Barmada SJ, Todd PK. DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation. Embo Reports. e47498. PMID 31347257 DOI: 10.15252/Embr.201847498 |
0.83 |
|
| 2019 |
Rodriguez CM, Todd PK. New pathologic mechanisms in nucleotide repeat expansion disorders. Neurobiology of Disease. 104515. PMID 31229686 DOI: 10.1016/J.Nbd.2019.104515 |
0.743 |
|
| 2019 |
Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes & Development. PMID 31171704 DOI: 10.1101/Gad.324715.119 |
0.809 |
|
| 2019 |
Rodriguez CM, Chun SY, Mills RE, Todd PK. Translation of upstream open reading frames in a model of neuronal differentiation. Bmc Genomics. 20: 391. PMID 31109297 DOI: 10.1186/S12864-019-5775-1 |
0.687 |
|
| 2018 |
Haenfler JM, Skariah G, Rodriguez CM, Monteiro da Rocha A, Parent JM, Smith GD, Todd PK. Targeted Reactivation of Transcription in Fragile X Syndrome Embryonic Stem Cells. Frontiers in Molecular Neuroscience. 11: 282. PMID 30158855 DOI: 10.3389/Fnmol.2018.00282 |
0.785 |
|
| 2018 |
Glineburg MR, Todd PK, Charlet-Berguerand N, Sellier C. Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome. Brain Research. PMID 29453961 DOI: 10.1016/j.brainres.2018.02.006 |
0.499 |
|
| 2017 |
Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd PK. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications. 8: 2005. PMID 29222490 DOI: 10.1038/S41467-017-02200-0 |
0.803 |
|
| 2017 |
Sellier C, Buijsen RA, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, ... ... Todd PK, et al. Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome. Neuron. PMID 28065649 DOI: 10.1016/J.Neuron.2016.12.016 |
0.648 |
|
| 2016 |
Chun SY, Rodriguez CM, Todd PK, Mills RE. SPECtre: a spectral coherence--based classifier of actively translated transcripts from ribosome profiling sequence data. Bmc Bioinformatics. 17: 482. PMID 27884106 DOI: 10.1186/S12859-016-1355-4 |
0.655 |
|
| 2016 |
Flores BN, Dulchavsky ME, Krans A, Sawaya MR, Paulson HL, Todd PK, Barmada SJ, Ivanova MI. Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. Plos One. 11: e0165084. PMID 27776165 DOI: 10.1371/journal.pone.0165084 |
0.503 |
|
| 2016 |
Krans A, Kearse MG, Todd PK. RAN translation from antisense CCG repeats in Fragile X Tremor/Ataxia Syndrome. Annals of Neurology. PMID 27761921 DOI: 10.1002/Ana.24800 |
0.817 |
|
| 2016 |
Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD. Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome. Acs Chemical Biology. PMID 27276216 DOI: 10.1021/Acschembio.6B00147 |
0.59 |
|
| 2016 |
He F, Jones JM, Figueroa-Romero C, Zhang D, Feldman EL, Goutman SA, Meisler MH, Callaghan BC, Todd PK. Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci. Neurology. Genetics. 2: e71. PMID 27274540 DOI: 10.1212/Nxg.0000000000000071 |
0.476 |
|
| 2016 |
Green KM, Linsalata AE, Todd PK. RAN translation-what makes it run? Brain Research. PMID 27060770 DOI: 10.1016/j.brainres.2016.04.003 |
0.835 |
|
| 2016 |
Kearse MG, Green KM, Krans A, Rodriguez CM, Linsalata AE, Goldstrohm AC, Todd PK. CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins. Molecular Cell. PMID 27041225 DOI: 10.1016/J.Molcel.2016.02.034 |
0.807 |
|
| 2015 |
Oh SY, He F, Krans A, Frazer M, Taylor JP, Paulson HL, Todd PK. RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome. Human Molecular Genetics. 24: 4317-26. PMID 25954027 DOI: 10.1093/Hmg/Ddv165 |
0.775 |
|
| 2014 |
Renoux AJ, Carducci NM, Ahmady AA, Todd PK. Fragile X mental retardation protein expression in Alzheimer's disease. Frontiers in Genetics. 5: 360. PMID 25452762 DOI: 10.3389/fgene.2014.00360 |
0.611 |
|
| 2014 |
deLorimier E, Coonrod LA, Copperman J, Taber A, Reister EE, Sharma K, Todd PK, Guenza MG, Berglund JA. Modifications to toxic CUG RNAs induce structural stability, rescue mis-splicing in a myotonic dystrophy cell model and reduce toxicity in a myotonic dystrophy zebrafish model. Nucleic Acids Research. 42: 12768-78. PMID 25303993 DOI: 10.1093/Nar/Gku941 |
0.323 |
|
| 2014 |
Kearse MG, Todd PK. Repeat-associated non-AUG translation and its impact in neurodegenerative disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 721-31. PMID 25005000 DOI: 10.1007/S13311-014-0292-Z |
0.822 |
|
| 2014 |
He F, Krans A, Freibaum BD, Taylor JP, Todd PK. TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1. Human Molecular Genetics. 23: 5036-51. PMID 24920338 DOI: 10.1093/Hmg/Ddu216 |
0.62 |
|
| 2014 |
Renoux AJ, Sala-Hamrick KJ, Carducci NM, Frazer M, Halsey KE, Sutton MA, Dolan DF, Murphy GG, Todd PK. Impaired sensorimotor gating in Fmr1 knock out and Fragile X premutation model mice. Behavioural Brain Research. 267: 42-5. PMID 24657592 DOI: 10.1016/J.Bbr.2014.03.013 |
0.719 |
|
| 2014 |
Todd PK, Ackall FY, Hur J, Sharma K, Paulson HL, Dowling JJ. Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1. Disease Models & Mechanisms. 7: 143-55. PMID 24092878 DOI: 10.1242/Dmm.012427 |
0.588 |
|
| 2013 |
Todd PK, Paulson HL. C9orf72-associated FTD/ALS: when less is more. Neuron. 80: 257-8. PMID 24139028 DOI: 10.1016/j.neuron.2013.10.010 |
0.499 |
|
| 2013 |
Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, et al. CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome. Neuron. 78: 440-55. PMID 23602499 DOI: 10.1016/J.Neuron.2013.03.026 |
0.85 |
|
| 2013 |
Meisler MH, Grant AE, Jones JM, Lenk GM, He F, Todd PK, Kamali M, Albin RL, Lieberman AP, Langenecker SA, McInnis MG. C9ORF72 expansion in a family with bipolar disorder. Bipolar Disorders. 15: 326-32. PMID 23551834 DOI: 10.1111/Bdi.12063 |
0.485 |
|
| 2013 |
Sellier C, Freyermuth F, Tabet R, Tran T, He F, Ruffenach F, Alunni V, Moine H, Thibault C, Page A, Tassone F, Willemsen R, Disney MD, Hagerman PJ, Todd PK, et al. Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome. Cell Reports. 3: 869-80. PMID 23478018 DOI: 10.1016/J.Celrep.2013.02.004 |
0.599 |
|
| 2013 |
Iliff AJ, Renoux AJ, Krans A, Usdin K, Sutton MA, Todd PK. Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice. Human Molecular Genetics. 22: 1180-92. PMID 23250915 DOI: 10.1093/hmg/dds525 |
0.813 |
|
| 2013 |
Todd P, Oh S, Krans A, He F, Sellier C, Frazer M, Renoux A, Chen K, Scaglione K, Basrur V, Elenitoba-Johnson K, Vonsattel J, Louis E, Sutton M, Taylor J, et al. CGG Repeat-Associated Translation Mediates Neurodegeneration in Fragile X Tremor Ataxia Syndrome Neuron. 79: 402. DOI: 10.1016/j.neuron.2013.07.008 |
0.646 |
|
| 2012 |
Todd PK, Paulson HL. Drug discovery: Kill the messenger where it lives. Nature. 488: 36-8. PMID 22859197 DOI: 10.1038/488036a |
0.392 |
|
| 2012 |
Renoux AJ, Todd PK. Neurodegeneration the RNA way. Progress in Neurobiology. 97: 173-89. PMID 22079416 DOI: 10.1016/j.pneurobio.2011.10.006 |
0.596 |
|
| 2011 |
He F, Todd PK. Epigenetics in nucleotide repeat expansion disorders. Seminars in Neurology. 31: 470-83. PMID 22266885 DOI: 10.1055/S-0031-1299786 |
0.505 |
|
| 2010 |
Todd PK, Oh SY, Krans A, Pandey UB, Di Prospero NA, Min KT, Taylor JP, Paulson HL. Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome. Plos Genetics. 6: e1001240. PMID 21170301 DOI: 10.1371/Journal.Pgen.1001240 |
0.799 |
|
| 2010 |
Todd PK, Paulson HL. RNA-mediated neurodegeneration in repeat expansion disorders. Annals of Neurology. 67: 291-300. PMID 20373340 DOI: 10.1002/ana.21948 |
0.648 |
|
| 2008 |
Nedelsky NB, Todd PK, Taylor JP. Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection. Biochimica Et Biophysica Acta. 1782: 691-9. PMID 18930136 DOI: 10.1016/J.Bbadis.2008.10.002 |
0.77 |
|
| 2003 |
Todd PK, Mack KJ, Malter JS. The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proceedings of the National Academy of Sciences of the United States of America. 100: 14374-8. PMID 14614133 DOI: 10.1073/Pnas.2336265100 |
0.771 |
|
| 2003 |
Todd PK, Malter JS, Mack KJ. Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors. Brain Research. Molecular Brain Research. 110: 267-78. PMID 12591163 DOI: 10.1016/S0169-328X(02)00657-5 |
0.735 |
|
| 2002 |
Todd PK, Malter JS. Fragile X mental retardation protein in plasticity and disease. Journal of Neuroscience Research. 70: 623-30. PMID 12424729 DOI: 10.1002/Jnr.10453 |
0.636 |
|
| 2001 |
Todd PK, Mack KJ. Phosphorylation, CREB, and Mental Retardation. Pediatric Research. 50: 672. PMID 11726717 DOI: 10.1203/00006450-200112000-00002 |
0.521 |
|
| 2000 |
Todd PK, Mack KJ. Sensory stimulation increases cortical expression of the fragile X mental retardation protein in vivo. Brain Research. Molecular Brain Research. 80: 17-25. PMID 11039725 DOI: 10.1016/S0169-328X(00)00098-X |
0.65 |
|
| 1997 |
Kuczenski R, Segal DS, Todd PK. Behavioral sensitization and extracellular dopamine responses to amphetamine after various treatments. Psychopharmacology. 134: 221-9. PMID 9438672 DOI: 10.1007/S002130050445 |
0.607 |
|
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