Peter Todd - Publications

University of Michigan University of Michigan, Ann Arbor, Ann Arbor, MI 

49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Skariah G, Todd PK. Translational control in aging and neurodegeneration. Wiley Interdisciplinary Reviews. Rna. e1628. PMID 32954679 DOI: 10.1002/wrna.1628  1
2020 He F, Flores BN, Krans A, Frazer M, Natla S, Niraula S, Adefioye O, Barmada SJ, Todd PK. The carboxyl termini of RAN translated GGGGCC nucleotide repeat expansions modulate toxicity in models of ALS/FTD. Acta Neuropathologica Communications. 8: 122. PMID 32753055 DOI: 10.1186/s40478-020-01002-8  0.96
2020 Rodriguez CM, Wright SE, Kearse MG, Haenfler JM, Flores BN, Liu Y, Ifrim MF, Glineburg MR, Krans A, Jafar-Nejad P, Sutton MA, Bassell GJ, Parent JM, Rigo F, Barmada SJ, ... Todd PK, et al. A native function for RAN translation and CGG repeats in regulating fragile X protein synthesis. Nature Neuroscience. PMID 32066985 DOI: 10.1038/s41593-020-0590-1  1
2019 Krans A, Skariah G, Zhang Y, Bayly B, Todd PK. Neuropathology of RAN translation proteins in fragile X-associated tremor/ataxia syndrome. Acta Neuropathologica Communications. 7: 152. PMID 31665086 DOI: 10.1186/s40478-019-0782-7  1
2019 Sacino AN, Prokop S, Walsh MA, Adamson J, Subramony SH, Krans A, Todd PK, Giasson BI, Yachnis AT. Fragile X-associated tremor ataxia syndrome with co-occurrent progressive supranuclear palsy-like neuropathology. Acta Neuropathologica Communications. 7: 158. PMID 31665069 DOI: 10.1186/s40478-019-0818-z  0.96
2019 Green KM, Sheth U, Flores BN, Wright SE, Sutter A, Kearse MG, Barmada S, Ivanova MI, Todd PK. High-throughput screening yields several small-molecule inhibitors of repeat-associated non-AUG translation. The Journal of Biological Chemistry. PMID 31649034 DOI: 10.1074/jbc.RA119.009951  1
2019 Linsalata AE, He F, Malik AM, Glineburg MR, Green KM, Natla S, Flores BN, Krans A, Archbold HC, Fedak SJ, Barmada SJ, Todd PK. DDX3X and specific initiation factors modulate FMR1 repeat-associated non-AUG-initiated translation. Embo Reports. e47498. PMID 31347257 DOI: 10.15252/embr.201847498  0.96
2019 Rodriguez CM, Todd PK. New pathologic mechanisms in nucleotide repeat expansion disorders. Neurobiology of Disease. 104515. PMID 31229686 DOI: 10.1016/j.nbd.2019.104515  0.84
2019 Kearse MG, Goldman DH, Choi J, Nwaezeapu C, Liang D, Green KM, Goldstrohm AC, Todd PK, Green R, Wilusz JE. Ribosome queuing enables non-AUG translation to be resistant to multiple protein synthesis inhibitors. Genes & Development. PMID 31171704 DOI: 10.1101/gad.324715.119  0.92
2019 Rodriguez CM, Chun SY, Mills RE, Todd PK. Translation of upstream open reading frames in a model of neuronal differentiation. Bmc Genomics. 20: 391. PMID 31109297 DOI: 10.1186/s12864-019-5775-1  0.84
2018 Haenfler JM, Skariah G, Rodriguez CM, Monteiro da Rocha A, Parent JM, Smith GD, Todd PK. Targeted Reactivation of Transcription in Fragile X Syndrome Embryonic Stem Cells. Frontiers in Molecular Neuroscience. 11: 282. PMID 30158855 DOI: 10.3389/fnmol.2018.00282  1
2018 Glineburg MR, Todd PK, Charlet-Berguerand N, Sellier C. Repeat-associated non-AUG (RAN) translation and other molecular mechanisms in Fragile X Tremor Ataxia Syndrome. Brain Research. PMID 29453961 DOI: 10.1016/j.brainres.2018.02.006  0.44
2017 Green KM, Glineburg MR, Kearse MG, Flores BN, Linsalata AE, Fedak SJ, Goldstrohm AC, Barmada SJ, Todd PK. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nature Communications. 8: 2005. PMID 29222490 DOI: 10.1038/s41467-017-02200-0  1
2017 Sellier C, Buijsen RA, He F, Natla S, Jung L, Tropel P, Gaucherot A, Jacobs H, Meziane H, Vincent A, Champy MF, Sorg T, Pavlovic G, Wattenhofer-Donze M, Birling MC, ... ... Todd PK, et al. Translation of Expanded CGG Repeats into FMRpolyG Is Pathogenic and May Contribute to Fragile X Tremor Ataxia Syndrome. Neuron. PMID 28065649 DOI: 10.1016/j.neuron.2016.12.016  0.96
2016 Chun SY, Rodriguez CM, Todd PK, Mills RE. SPECtre: a spectral coherence--based classifier of actively translated transcripts from ribosome profiling sequence data. Bmc Bioinformatics. 17: 482. PMID 27884106 DOI: 10.1186/s12859-016-1355-4  0.84
2016 Flores BN, Dulchavsky ME, Krans A, Sawaya MR, Paulson HL, Todd PK, Barmada SJ, Ivanova MI. Distinct C9orf72-Associated Dipeptide Repeat Structures Correlate with Neuronal Toxicity. Plos One. 11: e0165084. PMID 27776165 DOI: 10.1371/journal.pone.0165084  0.96
2016 Krans A, Kearse MG, Todd PK. RAN translation from antisense CCG repeats in Fragile X Tremor/Ataxia Syndrome. Annals of Neurology. PMID 27761921 DOI: 10.1002/ana.24800  1
2016 Yang WY, He F, Strack RL, Oh SY, Frazer M, Jaffrey SR, Todd PK, Disney MD. Small Molecule Recognition and Tools to Study Modulation of r(CGG)exp in Fragile X-Associated Tremor Ataxia Syndrome. Acs Chemical Biology. PMID 27276216 DOI: 10.1021/acschembio.6b00147  0.96
2016 He F, Jones JM, Figueroa-Romero C, Zhang D, Feldman EL, Goutman SA, Meisler MH, Callaghan BC, Todd PK. Screening for novel hexanucleotide repeat expansions at ALS- and FTD-associated loci. Neurology. Genetics. 2: e71. PMID 27274540 DOI: 10.1212/NXG.0000000000000071  0.96
2016 Green KM, Linsalata AE, Todd PK. RAN translation-what makes it run? Brain Research. PMID 27060770 DOI: 10.1016/j.brainres.2016.04.003  1
2016 Kearse MG, Green KM, Krans A, Rodriguez CM, Linsalata AE, Goldstrohm AC, Todd PK. CGG Repeat-Associated Non-AUG Translation Utilizes a Cap-Dependent Scanning Mechanism of Initiation to Produce Toxic Proteins. Molecular Cell. PMID 27041225 DOI: 10.1016/j.molcel.2016.02.034  1
2015 Oh SY, He F, Krans A, Frazer M, Taylor JP, Paulson HL, Todd PK. RAN translation at CGG repeats induces ubiquitin proteasome system impairment in models of fragile X-associated tremor ataxia syndrome. Human Molecular Genetics. 24: 4317-26. PMID 25954027 DOI: 10.1093/hmg/ddv165  1
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, et al. Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS. Neuron. 84: 239. PMID 28898625 DOI: 10.1016/j.neuron.2014.09.019  0.56
2014 Renoux AJ, Carducci NM, Ahmady AA, Todd PK. Fragile X mental retardation protein expression in Alzheimer's disease. Frontiers in Genetics. 5: 360. PMID 25452762 DOI: 10.3389/fgene.2014.00360  1
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, et al. Discovery of a biomarker and lead small molecules to target r(GGGGCC)-associated defects in c9FTD/ALS. Neuron. 83: 1043-50. PMID 25132468 DOI: 10.1016/j.neuron.2014.07.041  1
2014 Kearse MG, Todd PK. Repeat-associated non-AUG translation and its impact in neurodegenerative disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 11: 721-31. PMID 25005000 DOI: 10.1007/s13311-014-0292-z  1
2014 He F, Krans A, Freibaum BD, Taylor JP, Todd PK. TDP-43 suppresses CGG repeat-induced neurotoxicity through interactions with HnRNP A2/B1. Human Molecular Genetics. 23: 5036-51. PMID 24920338 DOI: 10.1093/hmg/ddu216  1
2014 Renoux AJ, Sala-Hamrick KJ, Carducci NM, Frazer M, Halsey KE, Sutton MA, Dolan DF, Murphy GG, Todd PK. Impaired sensorimotor gating in Fmr1 knock out and Fragile X premutation model mice. Behavioural Brain Research. 267: 42-5. PMID 24657592 DOI: 10.1016/j.bbr.2014.03.013  1
2014 Dang L, Dang X, Koralnik IJ, Todd PK. JC polyomavirus granule cell neuronopathy in a patient treated with rituximab. Jama Neurology. 71: 487-9. PMID 24515530 DOI: 10.1001/jamaneurol.2013.4668  1
2014 Todd PK, Ackall FY, Hur J, Sharma K, Paulson HL, Dowling JJ. Transcriptional changes and developmental abnormalities in a zebrafish model of myotonic dystrophy type 1. Disease Models & Mechanisms. 7: 143-55. PMID 24092878 DOI: 10.1242/dmm.012427  1
2014 Su Z, Zhang Y, Gendron TF, Bauer PO, Chew J, Yang WY, Fostvedt E, Jansen-West K, Belzil VV, Desaro P, Johnston A, Overstreet K, Oh SY, Todd PK, Berry JD, et al. Errata to Discovery of a biomarker and lead small molecules to target r(GGGGCC)-Associated Defects in c9FTD/ALS [Neuron, 83, (2014) 1043-1050] Neuron. 84: 239. DOI: 10.1016/j.neuron.2014.09.019  1
2013 Todd PK. Making sense of the antisense transcripts in C9FTD/ALS. Acta Neuropathologica. 126: 785-7. PMID 24178412 DOI: 10.1007/s00401-013-1201-y  1
2013 Todd PK, Paulson HL. C9orf72-associated FTD/ALS: when less is more. Neuron. 80: 257-8. PMID 24139028 DOI: 10.1016/j.neuron.2013.10.010  1
2013 Todd PK, Oh SY, Krans A, He F, Sellier C, Frazer M, Renoux AJ, Chen KC, Scaglione KM, Basrur V, Elenitoba-Johnson K, Vonsattel JP, Louis ED, Sutton MA, Taylor JP, et al. CGG repeat-associated translation mediates neurodegeneration in fragile X tremor ataxia syndrome. Neuron. 78: 440-55. PMID 23602499 DOI: 10.1016/j.neuron.2013.03.026  1
2013 Meisler MH, Grant AE, Jones JM, Lenk GM, He F, Todd PK, Kamali M, Albin RL, Lieberman AP, Langenecker SA, McInnis MG. C9ORF72 expansion in a family with bipolar disorder. Bipolar Disorders. 15: 326-32. PMID 23551834 DOI: 10.1111/bdi.12063  1
2013 Sellier C, Freyermuth F, Tabet R, Tran T, He F, Ruffenach F, Alunni V, Moine H, Thibault C, Page A, Tassone F, Willemsen R, Disney MD, Hagerman PJ, Todd PK, et al. Sequestration of DROSHA and DGCR8 by expanded CGG RNA repeats alters microRNA processing in fragile X-associated tremor/ataxia syndrome. Cell Reports. 3: 869-80. PMID 23478018 DOI: 10.1016/j.celrep.2013.02.004  1
2013 Iliff AJ, Renoux AJ, Krans A, Usdin K, Sutton MA, Todd PK. Impaired activity-dependent FMRP translation and enhanced mGluR-dependent LTD in Fragile X premutation mice. Human Molecular Genetics. 22: 1180-92. PMID 23250915 DOI: 10.1093/hmg/dds525  1
2012 Todd PK, Paulson HL. Drug discovery: Kill the messenger where it lives. Nature. 488: 36-8. PMID 22859197 DOI: 10.1038/488036a  1
2012 Renoux AJ, Todd PK. Neurodegeneration the RNA way. Progress in Neurobiology. 97: 173-89. PMID 22079416 DOI: 10.1016/j.pneurobio.2011.10.006  1
2011 He F, Todd PK. Epigenetics in nucleotide repeat expansion disorders. Seminars in Neurology. 31: 470-83. PMID 22266885 DOI: 10.1055/s-0031-1299786  1
2010 Todd PK, Oh SY, Krans A, Pandey UB, Di Prospero NA, Min KT, Taylor JP, Paulson HL. Histone deacetylases suppress CGG repeat-induced neurodegeneration via transcriptional silencing in models of fragile X tremor ataxia syndrome. Plos Genetics. 6: e1001240. PMID 21170301 DOI: 10.1371/journal.pgen.1001240  1
2010 Todd PK, Paulson HL. RNA-mediated neurodegeneration in repeat expansion disorders. Annals of Neurology. 67: 291-300. PMID 20373340 DOI: 10.1002/ana.21948  1
2008 Nedelsky NB, Todd PK, Taylor JP. Autophagy and the ubiquitin-proteasome system: collaborators in neuroprotection. Biochimica Et Biophysica Acta. 1782: 691-9. PMID 18930136 DOI: 10.1016/j.bbadis.2008.10.002  1
2003 Todd PK, Mack KJ, Malter JS. The fragile X mental retardation protein is required for type-I metabotropic glutamate receptor-dependent translation of PSD-95. Proceedings of the National Academy of Sciences of the United States of America. 100: 14374-8. PMID 14614133 DOI: 10.1073/pnas.2336265100  1
2003 Todd PK, Malter JS, Mack KJ. Whisker stimulation-dependent translation of FMRP in the barrel cortex requires activation of type I metabotropic glutamate receptors. Brain Research. Molecular Brain Research. 110: 267-78. PMID 12591163 DOI: 10.1016/S0169-328X(02)00657-5  1
2002 Todd PK, Malter JS. Fragile X mental retardation protein in plasticity and disease. Journal of Neuroscience Research. 70: 623-30. PMID 12424729 DOI: 10.1002/jnr.10453  1
2001 Todd PK, Mack KJ. Phosphorylation, CREB, and Mental Retardation. Pediatric Research. 50: 672. PMID 11726717 DOI: 10.1203/00006450-200112000-00002  1
2000 Todd PK, Mack KJ. Sensory stimulation increases cortical expression of the fragile X mental retardation protein in vivo. Brain Research. Molecular Brain Research. 80: 17-25. PMID 11039725 DOI: 10.1016/S0169-328X(00)00098-X  1
1997 Kuczenski R, Segal DS, Todd PK. Behavioral sensitization and extracellular dopamine responses to amphetamine after various treatments. Psychopharmacology. 134: 221-9. PMID 9438672 DOI: 10.1007/s002130050445  1
Show low-probability matches.