| Year |
Citation |
Score |
| 2024 |
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Willey S, Van Deynze K, Mumm C, Boyle AP, Cortese A, Ndayisaba A, Khurana V, Barmada SJ, et al. AAGGG repeat expansions trigger -independent synaptic dysregulation in human CANVAS neurons. Science Advances. 10: eadn2321. PMID 39231235 DOI: 10.1126/sciadv.adn2321 |
0.32 |
|
| 2024 |
Lam I, Ndayisaba A, Lewis AJ, Fu Y, Sagredo GT, Kuzkina A, Zaccagnini L, Celikag M, Sandoe J, Sanz RL, Vahdatshoar A, Martin TD, Morshed N, Ichihashi T, Tripathi A, ... ... Khurana V, et al. Rapid iPSC inclusionopathy models shed light on formation, consequence, and molecular subtype of α-synuclein inclusions. Neuron. PMID 39079530 DOI: 10.1016/j.neuron.2024.06.002 |
0.638 |
|
| 2024 |
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, ... ... Khurana V, et al. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology. PMID 38496508 DOI: 10.1101/2024.03.03.583145 |
0.706 |
|
| 2024 |
Santhosh Kumar S, Naseri NN, Pather SR, Hallacli E, Ndayisaba A, Buenaventura C, Acosta K, Roof J, Fazelinia H, Spruce LA, Luk K, Khurana V, Rhoades E, Shalem O. Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Science Advances. 10: eadj4767. PMID 38335281 DOI: 10.1126/sciadv.adj4767 |
0.333 |
|
| 2023 |
Maltby CJ, Krans A, Grudzien SJ, Palacios Y, Muiños J, Suárez A, Asher M, Khurana V, Barmada SJ, Dijkstra AA, Todd PK. AAGGG repeat expansions trigger RFC1-independent synaptic dysregulation in human CANVAS Neurons. Biorxiv : the Preprint Server For Biology. PMID 38168171 DOI: 10.1101/2023.12.13.571345 |
0.315 |
|
| 2022 |
Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Khurana V, et al. Correction to: Clinical trial-ready patient cohorts for multiple system atrophy: coupling biospecimen and iPSC banking to longitudinal deep-phenotyping. Cerebellum (London, England). PMID 36456723 DOI: 10.1007/s12311-022-01501-5 |
0.499 |
|
| 2022 |
Raja WK, Neves E, Burke C, Jiang X, Xu P, Rhodes KJ, Khurana V, Scannevin RH, Chung CY. Patient-derived three-dimensional cortical neurospheres to model Parkinson's disease. Plos One. 17: e0277532. PMID 36454869 DOI: 10.1371/journal.pone.0277532 |
0.372 |
|
| 2022 |
Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, ... ... Khurana V, et al. Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum (London, England). PMID 36190676 DOI: 10.1007/s12311-022-01471-8 |
0.621 |
|
| 2022 |
Kim J, Young GS, Willett AS, Pitaro AT, Crotty GF, Mesidor M, Jones KA, Bay C, Zhang M, Feany MB, Xu X, Qin L, Khurana V. Toward More Accessible Fully Automated 3D Volumetric MRI Decision Trees for the Differential Diagnosis of Multiple System Atrophy, Related Disorders, and Age-Matched Healthy Subjects. Cerebellum (London, England). PMID 36156185 DOI: 10.1007/s12311-022-01472-7 |
0.536 |
|
| 2022 |
Hallacli E, Kayatekin C, Nazeen S, Wang XH, Sheinkopf Z, Sathyakumar S, Sarkar S, Jiang X, Dong X, Di Maio R, Wang W, Keeney MT, Felsky D, Sandoe J, Vahdatshoar A, ... ... Khurana V, et al. The Parkinson's disease protein alpha-synuclein is a modulator of processing bodies and mRNA stability. Cell. 185: 2035-2056.e33. PMID 35688132 DOI: 10.1016/j.cell.2022.05.008 |
0.78 |
|
| 2019 |
Carmona-Abellan M, Gabilondo I, Murueta-Goyena A, Khurana V, Tijero B, Luquin MR, Acera M, Del Pino R, Gardeazabal J, Martínez-Valbuena I, Sanchez-Pernaute R, Gómez-Esteban JC. Small fiber neuropathy and phosphorylated alpha-synuclein in the skin of E46K-SNCA mutation carriers. Parkinsonism & Related Disorders. PMID 31178336 DOI: 10.1016/J.Parkreldis.2019.05.038 |
0.339 |
|
| 2019 |
Lam I, Hallacli E, Khurana V. Proteome-Scale Mapping of Perturbed Proteostasis in Living Cells. Cold Spring Harbor Perspectives in Biology. PMID 30910772 DOI: 10.1101/Cshperspect.A034124 |
0.447 |
|
| 2019 |
Sanz R, Ovando-Roche P, Udeshi ND, Carr SA, Chung CY, Khurana V. In Situ Peroxidase Labeling and Mass Spectrometry of Alpha-Synuclein in Rat Cortical Neurons. Methods in Molecular Biology (Clifton, N.J.). 1948: 235-246. PMID 30771182 DOI: 10.1007/978-1-4939-9124-2_18 |
0.317 |
|
| 2018 |
Vincent BM, Tardiff DF, Piotrowski JS, Aron R, Lucas MC, Chung CY, Bacherman H, Chen Y, Pires M, Subramaniam R, Doshi DB, Sadlish H, Raja WK, Solís EJ, Khurana V, et al. Inhibiting Stearoyl-CoA Desaturase Ameliorates α-Synuclein Cytotoxicity. Cell Reports. 25: 2742-2754.e31. PMID 30517862 DOI: 10.1016/J.Celrep.2018.11.028 |
0.452 |
|
| 2017 |
Jarosz DF, Khurana V. Specification of Physiologic and Disease States by Distinct Proteins and Protein Conformations. Cell. 171: 1001-1014. PMID 29149602 DOI: 10.1016/J.Cell.2017.10.047 |
0.66 |
|
| 2017 |
Mittal S, Bjørnevik K, Im DS, Flierl A, Dong X, Locascio JJ, Abo KM, Long E, Jin M, Xu B, Xiang YK, Rochet JC, Engeland A, Rizzu P, Heutink P, ... ... Khurana V, et al. β2-Adrenoreceptor is a regulator of the α-synuclein gene driving risk of Parkinson's disease. Science (New York, N.Y.). 357: 891-898. PMID 28860381 DOI: 10.1126/Science.Aaf3934 |
0.39 |
|
| 2017 |
Chung CY, Khurana V, Yi S, Sahni N, Loh KH, Auluck PK, Baru V, Udeshi ND, Freyzon Y, Carr SA, Hill DE, Vidal M, Ting AY, Lindquist S. In Situ Peroxidase Labeling and Mass-Spectrometry Connects Alpha-Synuclein Directly to Endocytic Trafficking and mRNA Metabolism in Neurons. Cell Systems. PMID 28131823 DOI: 10.1016/J.Cels.2017.01.002 |
0.754 |
|
| 2017 |
Khurana V, Peng J, Chung CY, Auluck PK, Fanning S, Tardiff DF, Bartels T, Koeva M, Eichhorn SW, Benyamini H, Lou Y, Nutter-Upham A, Baru V, Freyzon Y, Tuncbag N, et al. Genome-Scale Networks Link Neurodegenerative Disease Genes to α-Synuclein through Specific Molecular Pathways. Cell Systems. PMID 28131822 DOI: 10.1016/J.Cels.2016.12.011 |
0.745 |
|
| 2015 |
Khurana V, Tardiff DF, Chung CY, Lindquist S. Toward stem cell-based phenotypic screens for neurodegenerative diseases. Nature Reviews. Neurology. 11: 339-50. PMID 25986505 DOI: 10.1038/Nrneurol.2015.79 |
0.597 |
|
| 2015 |
Sahni N, Yi S, Taipale M, Fuxman Bass JI, Coulombe-Huntington J, Yang F, Peng J, Weile J, Karras GI, Wang Y, Kovács IA, Kamburov A, Krykbaeva I, Lam MH, Tucker G, ... Khurana V, et al. Widespread macromolecular interaction perturbations in human genetic disorders. Cell. 161: 647-60. PMID 25910212 DOI: 10.1016/J.Cell.2015.04.013 |
0.763 |
|
| 2014 |
Tardiff DF, Khurana V, Chung CY, Lindquist S. From yeast to patient neurons and back again: powerful new discovery platform. Movement Disorders : Official Journal of the Movement Disorder Society. 29: 1231-40. PMID 25131316 DOI: 10.1002/Mds.25989 |
0.652 |
|
| 2013 |
Tardiff DF, Jui NT, Khurana V, Tambe MA, Thompson ML, Chung CY, Kamadurai HB, Kim HT, Lancaster AK, Caldwell KA, Caldwell GA, Rochet JC, Buchwald SL, Lindquist S. Yeast reveal a "druggable" Rsp5/Nedd4 network that ameliorates α-synuclein toxicity in neurons. Science (New York, N.Y.). 342: 979-83. PMID 24158909 DOI: 10.1126/Science.1245321 |
0.604 |
|
| 2013 |
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296 |
0.77 |
|
| 2013 |
Ding H, Dhima K, Lockhart KC, Locascio JJ, Hoesing AN, Duong K, Trisini-Lipsanopoulos A, Hayes MT, Sohur US, Wills AM, Mollenhauer B, Flaherty AW, Hung AY, Mejia N, Khurana V, et al. Unrecognized vitamin D3 deficiency is common in Parkinson disease: Harvard Biomarker Study. Neurology. 81: 1531-7. PMID 24068787 DOI: 10.1212/Wnl.0B013E3182A95818 |
0.317 |
|
| 2012 |
Khurana V, Merlo P, DuBoff B, Fulga TA, Sharp KA, Campbell SD, Götz J, Feany MB. A neuroprotective role for the DNA damage checkpoint in tauopathy. Aging Cell. 11: 360-2. PMID 22181010 DOI: 10.1111/J.1474-9726.2011.00778.X |
0.716 |
|
| 2011 |
Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, et al. Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations. Cell. 146: 318-31. PMID 21757228 DOI: 10.1016/J.Cell.2011.06.019 |
0.748 |
|
| 2010 |
Khurana V, Elson-Schwab I, Fulga TA, Sharp KA, Loewen CA, Mulkearns E, Tyynelä J, Scherzer CR, Feany MB. Lysosomal dysfunction promotes cleavage and neurotoxicity of tau in vivo. Plos Genetics. 6: e1001026. PMID 20664788 DOI: 10.1371/Journal.Pgen.1001026 |
0.746 |
|
| 2010 |
Khurana V, Lindquist S. Modelling neurodegeneration in Saccharomyces cerevisiae: why cook with baker's yeast? Nature Reviews. Neuroscience. 11: 436-49. PMID 20424620 DOI: 10.1038/Nrn2809 |
0.58 |
|
| 2009 |
Atwood C, Brewer G, Herrup K, Kim D, Khurana V, Lamb B, Langley B, Leitner M, Muresan V, Neve R, Park K, Patzke H, Strobel G, Tsai LH, Yankner B. Alzheimer research forum live discussion: Meet new players, histone deacetylase and sirtuin - Will they help the cell cycle, DNA repair, and gene expression break into alzheimerology's major league? Journal of Alzheimer's Disease. 17: 233-238. PMID 19433902 DOI: 10.3233/Jad-2009-1084 |
0.309 |
|
| 2008 |
Khurana V. Modeling Tauopathy in the fruit fly Drosophila melanogaster. Journal of Alzheimer's Disease : Jad. 15: 541-53. PMID 19096155 DOI: 10.3233/Jad-2008-15403 |
0.434 |
|
| 2007 |
Fulga TA, Elson-Schwab I, Khurana V, Steinhilb ML, Spires TL, Hyman BT, Feany MB. Abnormal bundling and accumulation of F-actin mediates tau-induced neuronal degeneration in vivo. Nature Cell Biology. 9: 139-48. PMID 17187063 DOI: 10.1038/Ncb1528 |
0.743 |
|
| 2007 |
Khurana V, Feany MB. Connecting cell-cycle activation to neurodegeneration in Drosophila. Biochimica Et Biophysica Acta. 1772: 446-56. PMID 17141486 DOI: 10.1016/J.Bbadis.2006.10.007 |
0.628 |
|
| 2006 |
Gavin BA, Dolph MJ, Deleault NR, Geoghegan JC, Khurana V, Feany MB, Dolph PJ, Supattapone S. Accelerated accumulation of misfolded prion protein and spongiform degeneration in a Drosophila model of Gerstmann-Sträussler-Scheinker syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12408-14. PMID 17135402 DOI: 10.1523/Jneurosci.3372-06.2006 |
0.651 |
|
| 2006 |
Khurana V, Lu Y, Steinhilb ML, Oldham S, Shulman JM, Feany MB. TOR-mediated cell-cycle activation causes neurodegeneration in a Drosophila tauopathy model. Current Biology : Cb. 16: 230-41. PMID 16461276 DOI: 10.1016/J.Cub.2005.12.042 |
0.639 |
|
| 2005 |
Khurana V, Fulga TA, Feany MB. Senseless makes sense for spinocerebellar ataxia-1. Nature Neuroscience. 8: 1422-4. PMID 16251977 DOI: 10.1038/Nn1105-1422 |
0.653 |
|
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