Hermona Soreq - Publications

Affiliations: 
Hebrew University, Jerusalem, Jerusalem, Israel 

301 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Lobentanzer S, Hanin G, Klein J, Soreq H. Integrative Transcriptomics Reveals Sexually Dimorphic Control of the Cholinergic/Neurokine Interface in Schizophrenia and Bipolar Disorder. Cell Reports. 29: 764-777.e5. PMID 31618642 DOI: 10.1016/j.celrep.2019.09.017  0.44
2019 Lackie RE, Razzaq AR, Farhan SMK, Qiu LR, Moshitzky G, Beraldo FH, Lopes MH, Maciejewski A, Gros R, Fan J, Choy WY, Greenberg DS, Martins VR, Duennwald ML, Lerch JP, ... Soreq H, et al. Modulation of hippocampal neuronal resilience during aging by the Hsp70/Hsp90 co-chaperone STI1. Journal of Neurochemistry. PMID 31562773 DOI: 10.1111/jnc.14882  0.64
2019 Simchovitz A, Hanan M, Niederhoffer N, Madrer N, Yayon N, Bennett ER, Greenberg DS, Kadener S, Soreq H. NEAT1 is overexpressed in Parkinson's disease and confers drug-inducible neuroprotection from oxidative stress. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201900830R. PMID 31311324 DOI: 10.1096/fj.201900830R  0.64
2018 Shaheen M, Schindler L, Saar-Ashkenazy R, Bani Odeh K, Soreq H, Friedman A, Kirschbaum C. Victims of war-Psychoendocrine evidence for the impact of traumatic stress on psychological well-being of adolescents growing up during the Israeli-Palestinian conflict. Psychophysiology. e13271. PMID 30101980 DOI: 10.1111/psyp.13271  0.92
2018 Meydan C, Bekenstein U, Soreq H. Molecular Regulatory Pathways Link Sepsis With Metabolic Syndrome: Non-coding RNA Elements Underlying the Sepsis/Metabolic Cross-Talk. Frontiers in Molecular Neuroscience. 11: 189. PMID 29922126 DOI: 10.3389/fnmol.2018.00189  0.44
2018 Deshaies JE, Shkreta L, Moszczynski AJ, Sidibé H, Semmler S, Fouillen A, Bennett ER, Bekenstein U, Destroismaisons L, Toutant J, Delmotte Q, Volkening K, Stabile S, Aulas A, Khalfallah Y, ... Soreq H, et al. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. PMID 29562314 DOI: 10.1093/brain/awy062  0.44
2017 Pinho R, Guedes LC, Soreq L, Lobo PP, Mestre T, Coelho M, Rosa MM, Gonçalves N, Wales P, Mendes T, Gerhardt E, Fahlbusch C, Bonifati V, Bonin M, Miltenberger-Miltényi G, ... ... Soreq H, et al. Correction: Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles. Plos One. 12: e0190552. PMID 29284061 DOI: 10.1371/journal.pone.0190552  0.8
2017 Barbash S, Garfinkel BP, Maoz R, Simchovitz A, Nadorp B, Guffanti A, Bennett ER, Nadeau C, Türk A, Paul L, Reda T, Li Y, Buchman AS, Greenberg DS, Seitz A, ... ... Soreq H, et al. Alzheimer's brains show inter-related changes in RNA and lipid metabolism. Neurobiology of Disease. PMID 28630030 DOI: 10.1016/j.nbd.2017.06.008  0.64
2017 Bekenstein U, Mishra N, Milikovsky DZ, Hanin G, Zelig D, Sheintuch L, Berson A, Greenberg DS, Friedman A, Soreq H. Dynamic changes in murine forebrain miR-211 expression associate with cholinergic imbalances and epileptiform activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28584127 DOI: 10.1073/pnas.1701201114  0.92
2017 Hanin G, Yayon N, Tzur Y, Haviv R, Bennett ER, Udi S, Krishnamoorthy YR, Kotsiliti E, Zangen R, Efron B, Tam J, Pappo O, Shteyer E, Pikarsky E, Heikenwalder M, ... ... Soreq H, et al. miRNA-132 induces hepatic steatosis and hyperlipidaemia by synergistic multitarget suppression. Gut. PMID 28381526 DOI: 10.1136/gutjnl-2016-312869  0.64
2017 Simchovitz A, Heneka MT, Soreq H. Personalized genetics of the cholinergic blockade of neuroinflammation. Journal of Neurochemistry. PMID 28326544 DOI: 10.1111/jnc.13928  0.56
2017 Mishra N, Friedson L, Hanin G, Bekenstein U, Volovich M, Bennett ER, Greenberg DS, Soreq H. Antisense miR-132 blockade via the AChE-R splice variant mitigates cortical inflammation. Scientific Reports. 7: 42755. PMID 28209997 DOI: 10.1038/srep42755  0.64
2017 Lasser-Katz E, Simchovitz A, Chiu WH, Oertel WH, Sharon R, Soreq H, Roeper J, Goldberg JA. Mutant α-Synuclein Overexpression Induces Stressless Pacemaking in Vagal Motoneurons at Risk in Parkinson's Disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 47-57. PMID 28053029 DOI: 10.1523/JNEUROSCI.1079-16.2017  0.56
2016 Pinho R, Guedes LC, Soreq L, Lobo PP, Mestre T, Coelho M, Rosa MM, Gonçalves N, Wales P, Mendes T, Gerhardt E, Fahlbusch C, Bonifati V, Bonin M, Miltenberger-Miltényi G, ... ... Soreq H, et al. Gene Expression Differences in Peripheral Blood of Parkinson's Disease Patients with Distinct Progression Profiles. Plos One. 11: e0157852. PMID 27322389 DOI: 10.1371/journal.pone.0157852  0.8
2016 Kolisnyk B, Al-Onaizi M, Soreq L, Barbash S, Bekenstein U, Haberman N, Hanin G, Kish MT, Souza da Silva J, Fahnestock M, Ule J, Soreq H, Prado VF, Prado MA. Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology. Cerebral Cortex (New York, N.Y. : 1991). PMID 27312991 DOI: 10.1093/cercor/bhw177  0.8
2016 Kolisnyk B, Al-Onaizi MA, Xu J, Parfitt GM, Ostapchenko VG, Hanin G, Soreq H, Prado MA, Prado VF. Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 6287-96. PMID 27277805 DOI: 10.1523/JNEUROSCI.4614-15.2016  0.44
2016 Lykhmus O, Mishra N, Koval L, Kalashnyk O, Gergalova G, Uspenska K, Komisarenko S, Soreq H, Skok M. Molecular Mechanisms Regulating LPS-Induced Inflammation in the Brain. Frontiers in Molecular Neuroscience. 9: 19. PMID 27013966 DOI: 10.3389/fnmol.2016.00019  0.44
2015 Simchovitz A, Soreq L, Soreq H. Transcriptome profiling in Parkinson's leukocytes: from early diagnostics to neuroimmune therapeutic prospects. Current Opinion in Pharmacology. 26: 102-109. PMID 26609801 DOI: 10.1016/j.coph.2015.10.007  0.92
2015 Kaufer D, Friedman A, Seidman S, Soreq H. Corrigendum: Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature. PMID 26605528 DOI: 10.1038/nature16180  0.92
2015 Soreq L, Salomonis N, Israel Z, Bergman H, Soreq H. Analyzing alternative splicing data of splice junction arrays from Parkinson patients' leukocytes before and after deep brain stimulation as compared with control donors. Genomics Data. 5: 340-3. PMID 26484282 DOI: 10.1016/j.gdata.2015.07.014  0.8
2015 Soreq L, Salomonis N, Guffanti A, Bergman H, Israel Z, Soreq H. Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson's disease patients prior to and following deep brain stimulation treatment. Genomics Data. 3: 57-60. PMID 26484149 DOI: 10.1016/j.gdata.2014.11.009  0.8
2015 Cooper G, Lasser-Katz E, Simchovitz A, Sharon R, Soreq H, Surmeier DJ, Goldberg JA. Functional segregation of voltage-activated calcium channels in motoneurons of the dorsal motor nucleus of the vagus. Journal of Neurophysiology. 114: 1513-20. PMID 26156385 DOI: 10.1152/jn.00432.2014  0.92
2015 Soreq H. Checks and balances on cholinergic signaling in brain and body function. Trends in Neurosciences. 38: 448-58. PMID 26100140 DOI: 10.1016/j.tins.2015.05.007  0.92
2015 Atsmon J, Brill-Almon E, Nadri-Shay C, Chertkoff R, Alon S, Shaikevich D, Volokhov I, Haim KY, Bartfeld D, Shulman A, Ruderfer I, Ben-Moshe T, Shilovitzky O, Soreq H, Shaaltiel Y. Preclinical and first-in-human evaluation of PRX-105, a PEGylated, plant-derived, recombinant human acetylcholinesterase-R. Toxicology and Applied Pharmacology. 287: 202-9. PMID 26051873 DOI: 10.1016/j.taap.2015.06.004  0.92
2015 Nadorp B, Soreq H. Gut feeling: MicroRNA discriminators of the intestinal TLR9-cholinergic links. International Immunopharmacology. 29: 8-14. PMID 26003847 DOI: 10.1016/j.intimp.2015.04.058  0.92
2015 Blohberger J, Kunz L, Einwang D, Berg U, Berg D, Ojeda SR, Dissen GA, Fröhlich T, Arnold GJ, Soreq H, Lara H, Mayerhofer A. Readthrough acetylcholinesterase (AChE-R) and regulated necrosis: pharmacological targets for the regulation of ovarian functions? Cell Death & Disease. 6: e1685. PMID 25766324 DOI: 10.1038/cddis.2015.51  0.92
2015 Shenhar-Tsarfaty S, Yayon N, Waiskopf N, Shapira I, Toker S, Zaltser D, Berliner S, Ritov Y, Soreq H. Fear and C-reactive protein cosynergize annual pulse increases in healthy adults. Proceedings of the National Academy of Sciences of the United States of America. 112: E467-71. PMID 25535364 DOI: 10.1073/pnas.1418264112  0.92
2015 Soreq L, Salomonis N, Israel Z, Bergman H, Soreq H. Analyzing alternative splicing data of splice junction arrays from Parkinson patients' leukocytes before and after deep brain stimulation as compared with control donors Genomics Data. 5: 340-343. DOI: 10.1016/j.gdata.2015.07.014  0.92
2015 Soreq L, Salomonis N, Guffanti A, Bergman H, Israel Z, Soreq H. Whole transcriptome RNA sequencing data from blood leukocytes derived from Parkinson's disease patients prior to and following deep brain stimulation treatment Genomics Data. 3: 57-60. DOI: 10.1016/j.gdata.2014.11.009  0.92
2015 Soreq H. Meet the editorial board Current Alzheimer Research. 12: 199-200.  0.92
2014 Merbl Y, Sommer A, Chai O, Aroch I, Zimmerman G, Friedman A, Soreq H, Shamir MH. Tumor necrosis factor-α and interleukin-6 concentrations in cerebrospinal fluid of dogs after seizures. Journal of Veterinary Internal Medicine / American College of Veterinary Internal Medicine. 28: 1775-81. PMID 25308784 DOI: 10.1111/jvim.12462  0.92
2014 Soreq H. Novel roles of non-coding brain RNAs in health and disease. Frontiers in Molecular Neuroscience. 7: 55. PMID 25018693 DOI: 10.3389/fnmol.2014.00055  0.92
2014 Guffanti A, Simchovitz A, Soreq H. Emerging bioinformatics approaches for analysis of NGS-derived coding and non-coding RNAs in neurodegenerative diseases. Frontiers in Cellular Neuroscience. 8: 89. PMID 24723850 DOI: 10.3389/fncel.2014.00089  0.92
2014 Hanin G, Shenhar-Tsarfaty S, Yayon N, Yau YH, Hoe YY, Bennett ER, Sklan EH, Rao DC, Rankinen T, Bouchard C, Geifman-Shochat S, Shifman S, Greenberg DS, Soreq H. Competing targets of microRNA-608 affect anxiety and hypertension. Human Molecular Genetics. 23: 4569-80. PMID 24722204 DOI: 10.1093/hmg/ddu170  0.92
2014 Soreq L, Guffanti A, Salomonis N, Simchovitz A, Israel Z, Bergman H, Soreq H. Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing. Plos Computational Biology. 10: e1003517. PMID 24651478 DOI: 10.1371/journal.pcbi.1003517  0.92
2014 Greenberg DS, Soreq H. MicroRNA therapeutics in neurological disease. Current Pharmaceutical Design. 20: 6022-7. PMID 24641229  0.92
2014 Barbash S, Shifman S, Soreq H. Global coevolution of human microRNAs and their target genes. Molecular Biology and Evolution. 31: 1237-47. PMID 24600049 DOI: 10.1093/molbev/msu090  0.92
2014 Nadorp B, Soreq H. Predicted overlapping microRNA regulators of acetylcholine packaging and degradation in neuroinflammation-related disorders. Frontiers in Molecular Neuroscience. 7: 9. PMID 24574962 DOI: 10.3389/fnmol.2014.00009  0.92
2014 Arbel Y, Shenhar-Tsarfaty S, Waiskopf N, Finkelstein A, Halkin A, Revivo M, Berliner S, Herz I, Shapira I, Keren G, Soreq H, Banai S. Decline in serum cholinesterase activities predicts 2-year major adverse cardiac events. Molecular Medicine (Cambridge, Mass.). 20: 38-45. PMID 24395570 DOI: 10.2119/molmed.2013.00139  0.92
2014 Waiskopf N, Ofek K, Gilboa-Geffen A, Bekenstein U, Bahat A, Bennett ER, Podoly E, Livnah O, Hartmann G, Soreq H. AChE and RACK1 promote the anti-inflammatory properties of fluoxetine. Journal of Molecular Neuroscience : Mn. 53: 306-15. PMID 24258317 DOI: 10.1007/s12031-013-0174-6  0.92
2014 Shenhar-Tsarfaty S, Berliner S, Bornstein NM, Soreq H. Cholinesterases as biomarkers for parasympathetic dysfunction and inflammation-related disease. Journal of Molecular Neuroscience : Mn. 53: 298-305. PMID 24254221 DOI: 10.1007/s12031-013-0176-4  0.92
2014 Goll Y, Bekenstein U, Barbash S, Greenberg DS, Zangen R, Shoham S, Soreq H. Sustained Alzheimer's amyloid pathology in myeloid differentiation protein-88-deficient APPswe/PS1 mice. Neuro-Degenerative Diseases. 13: 58-60. PMID 24192711 DOI: 10.1159/000353689  0.92
2013 Kress M, Hüttenhofer A, Landry M, Kuner R, Favereaux A, Greenberg D, Bednarik J, Heppenstall P, Kronenberg F, Malcangio M, Rittner H, Uçeyler N, Trajanoski Z, Mouritzen P, Birklein F, ... ... Soreq H, et al. microRNAs in nociceptive circuits as predictors of future clinical applications. Frontiers in Molecular Neuroscience. 6: 33. PMID 24151455 DOI: 10.3389/fnmol.2013.00033  0.92
2013 Soreq L, Bergman H, Israel Z, Soreq H. Overlapping molecular signatures in Parkinson's patients' leukocytes before and after treatment and in mouse model brain regions. Cns & Neurological Disorders Drug Targets. 12: 1086-93. PMID 24040822  0.92
2013 Kolisnyk B, Al-Onaizi MA, Hirata PH, Guzman MS, Nikolova S, Barbash S, Soreq H, Bartha R, Prado MA, Prado VF. Forebrain deletion of the vesicular acetylcholine transporter results in deficits in executive function, metabolic, and RNA splicing abnormalities in the prefrontal cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 14908-20. PMID 24027290 DOI: 10.1523/JNEUROSCI.1933-13.2013  0.92
2013 Lau P, Bossers K, Janky R, Salta E, Frigerio CS, Barbash S, Rothman R, Sierksma AS, Thathiah A, Greenberg D, Papadopoulou AS, Achsel T, Ayoubi T, Soreq H, Verhaagen J, et al. Alteration of the microRNA network during the progression of Alzheimer's disease. Embo Molecular Medicine. 5: 1613-34. PMID 24014289 DOI: 10.1002/emmm.201201974  0.92
2013 Chai O, Sommer A, Zimmerman G, Soreq H, Friedman A, Bdolah-Abram T, Aroch I, Shamir MH. Acetylcholinesterase activity in the cerebrospinal fluid of dogs with seizures. Veterinary Journal (London, England : 1997). 198: 292-4. PMID 23988333 DOI: 10.1016/j.tvjl.2013.06.027  0.92
2013 von Bohlen Und Halbach O, Soreq H. Hippocampal Lipocalin 2: an emotional link between neurons and glia. Frontiers in Cellular Neuroscience. 7: 132. PMID 23986656 DOI: 10.3389/fncel.2013.00132  0.92
2013 Soreq L, Bergman H, Israel Z, Soreq H. Deep brain stimulation modulates nonsense-mediated RNA decay in Parkinson's patients leukocytes. Bmc Genomics. 14: 478. PMID 23865419 DOI: 10.1186/1471-2164-14-478  0.92
2013 Barbash S, Hanin G, Soreq H. Stereotactic injection of microRNA-expressing lentiviruses to the mouse hippocampus ca1 region and assessment of the behavioral outcome. Journal of Visualized Experiments : Jove. e50170. PMID 23792738 DOI: 10.3791/50170  0.92
2013 Soreq L, Salomonis N, Bronstein M, Greenberg DS, Israel Z, Bergman H, Soreq H. Small RNA sequencing-microarray analyses in Parkinson leukocytes reveal deep brain stimulation-induced splicing changes that classify brain region transcriptomes. Frontiers in Molecular Neuroscience. 6: 10. PMID 23717260 DOI: 10.3389/fnmol.2013.00010  0.92
2013 Maharshak N, Shenhar-Tsarfaty S, Aroyo N, Orpaz N, Guberman I, Canaani J, Halpern Z, Dotan I, Berliner S, Soreq H. MicroRNA-132 modulates cholinergic signaling and inflammation in human inflammatory bowel disease. Inflammatory Bowel Diseases. 19: 1346-53. PMID 23598815 DOI: 10.1097/MIB.0b013e318281f47d  0.92
2013 Barbash S, Soreq H. Statistically invalid classification of high throughput gene expression data. Scientific Reports. 3: 1102. PMID 23346359 DOI: 10.1038/srep01102  0.92
2013 Shenhar-Tsarfaty S, Waiskopf N, Ofek K, Shopin L, Usher S, Berliner S, Shapira I, Bornstein NM, Ritov Y, Soreq H, Ben Assayag E. Atherosclerosis and arteriosclerosis parameters in stroke patients associate with paraoxonase polymorphism and esterase activities. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 20: 891-8. PMID 23305304 DOI: 10.1111/ene.12074  0.92
2013 Bekenstein U, Soreq H. Heterogeneous nuclear ribonucleoprotein A1 in health and neurodegenerative disease: from structural insights to post-transcriptional regulatory roles. Molecular and Cellular Neurosciences. 56: 436-46. PMID 23247072 DOI: 10.1016/j.mcn.2012.12.002  0.92
2013 Alkalay A, Rabinovici GD, Zimmerman G, Agarwal N, Kaufer D, Miller BL, Jagust WJ, Soreq H. Plasma acetylcholinesterase activity correlates with intracerebral β-amyloid load. Current Alzheimer Research. 10: 48-56. PMID 23157337  0.92
2013 Ofek K, Soreq H. Cholinergic involvement and manipulation approaches in multiple system disorders. Chemico-Biological Interactions. 203: 113-9. PMID 22898318 DOI: 10.1016/j.cbi.2012.07.007  0.92
2013 Shaltiel G, Hanan M, Wolf Y, Barbash S, Kovalev E, Shoham S, Soreq H. Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target. Brain Structure & Function. 218: 59-72. PMID 22246100 DOI: 10.1007/s00429-011-0376-z  0.92
2013 Waiskopf N, Rotem R, Shweky I, Yedidya L, Soreq H, Banin U. Labeling Acetyl- and Butyrylcholinesterase Using Semiconductor Nanocrystals for Biological Applications Bionanoscience. 3: 1-11. DOI: 10.1007/s12668-012-0072-3  0.92
2012 Tsim K, Soreq H. Acetylcholinesterase: old questions and new developments. Frontiers in Molecular Neuroscience. 5: 101. PMID 23316131 DOI: 10.3389/fnmol.2012.00101  0.92
2012 Sussman J, Argov Z, Wirguin Y, Apolski S, Milic-Rasic V, Soreq H. Further developments with antisense treatment for myasthenia gravis. Annals of the New York Academy of Sciences. 1275: 13-6. PMID 23278572 DOI: 10.1111/j.1749-6632.2012.06825.x  0.92
2012 Sailaja BS, Cohen-Carmon D, Zimmerman G, Soreq H, Meshorer E. Stress-induced epigenetic transcriptional memory of acetylcholinesterase by HDAC4. Proceedings of the National Academy of Sciences of the United States of America. 109: E3687-95. PMID 23236169 DOI: 10.1073/pnas.1209990110  0.92
2012 Kim SY, Buckwalter M, Soreq H, Vezzani A, Kaufer D. Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis. Epilepsia. 53: 37-44. PMID 23134494 DOI: 10.1111/j.1528-1167.2012.03701.x  0.92
2012 Zimmerman G, Shaltiel G, Barbash S, Cohen J, Gasho CJ, Shenhar-Tsarfaty S, Shalev H, Berliner SA, Shelef I, Shoham S, Friedman A, Cohen H, Soreq H. Post-traumatic anxiety associates with failure of the innate immune receptor TLR9 to evade the pro-inflammatory NFκB pathway. Translational Psychiatry. 2: e78. PMID 22832815 DOI: 10.1038/tp.2012.4  0.92
2012 Ofek K, Schoknecht K, Melamed-Book N, Heinemann U, Friedman A, Soreq H. Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling. Journal of Cellular and Molecular Medicine. 16: 2736-44. PMID 22697296 DOI: 10.1111/j.1582-4934.2012.01596.x  0.92
2012 Gnatek Y, Zimmerman G, Goll Y, Najami N, Soreq H, Friedman A. Acetylcholinesterase loosens the brain's cholinergic anti-inflammatory response and promotes epileptogenesis. Frontiers in Molecular Neuroscience. 5: 66. PMID 22639569 DOI: 10.3389/fnmol.2012.00066  0.92
2012 Berson A, Barbash S, Shaltiel G, Goll Y, Hanin G, Greenberg DS, Ketzef M, Becker AJ, Friedman A, Soreq H. Cholinergic-associated loss of hnRNP-A/B in Alzheimer's disease impairs cortical splicing and cognitive function in mice. Embo Molecular Medicine. 4: 730-42. PMID 22628224 DOI: 10.1002/emmm.201100995  0.92
2012 Gilboa-Geffen A, Hartmann G, Soreq H. Stressing hematopoiesis and immunity: an acetylcholinesterase window into nervous and immune system interactions. Frontiers in Molecular Neuroscience. 5: 30. PMID 22448158 DOI: 10.3389/fnmol.2012.00030  0.92
2012 Soreq L, Ben-Shaul Y, Israel Z, Bergman H, Soreq H. Meta-analysis of genetic and environmental Parkinson's disease models reveals a common role of mitochondrial protection pathways. Neurobiology of Disease. 45: 1018-30. PMID 22198569 DOI: 10.1016/j.nbd.2011.12.021  0.92
2012 Barbash S, Soreq H. Threshold-independent meta-analysis of Alzheimer's disease transcriptomes shows progressive changes in hippocampal functions, epigenetics and microRNA regulation. Current Alzheimer Research. 9: 425-35. PMID 22191566  0.92
2012 Soreq L, Bergman H, Israel Z, Soreq H. Exon arrays reveal alternative splicing aberrations in Parkinson's disease leukocytes. Neuro-Degenerative Diseases. 10: 203-6. PMID 22156489 DOI: 10.1159/000332598  0.92
2012 Geyer BC, Ben Ari S, Barbash S, Kilbourne J, Mor TS, Soreq H. Nicotinic stimulation induces Tristetraprolin over-production and attenuates inflammation in muscle. Biochimica Et Biophysica Acta. 1823: 368-78. PMID 22093924 DOI: 10.1016/j.bbamcr.2011.11.001  0.92
2012 Ben Assayag E, Korczyn AD, Giladi N, Goldbourt U, Berliner AS, Shenhar-Tsarfaty S, Kliper E, Hallevi H, Shopin L, Hendler T, Baashat DB, Aizenstein O, Soreq H, Katz N, Solomon Z, et al. Predictors for poststroke outcomes: the Tel Aviv Brain Acute Stroke Cohort (TABASCO) study protocol. International Journal of Stroke : Official Journal of the International Stroke Society. 7: 341-7. PMID 22044517 DOI: 10.1111/j.1747-4949.2011.00652.x  0.92
2012 Benmoyal-Segal L, Soreq L, Ben-Shaul Y, Ben-Ari S, Ben-Moshe T, Aviel S, Bergman H, Soreq H. Adaptive alternative splicing correlates with less environmental risk of parkinsonism. Neuro-Degenerative Diseases. 9: 87-98. PMID 22042332 DOI: 10.1159/000331328  0.92
2012 Soreq L, Bergman H, Goll Y, Greenberg DS, Israel Z, Soreq H. Deep brain stimulation induces rapidly reversible transcript changes in Parkinson's leucocytes. Journal of Cellular and Molecular Medicine. 16: 1496-507. PMID 21910823 DOI: 10.1111/j.1582-4934.2011.01444.x  0.92
2012 Ben-Ari S, Ofek K, Barbash S, Meiri H, Kovalev E, Greenberg DS, Soreq H, Shoham S. Similar cation channels mediate protection from cerebellar exitotoxicity by exercise and inheritance. Journal of Cellular and Molecular Medicine. 16: 555-68. PMID 21507200 DOI: 10.1111/j.1582-4934.2011.01331.x  0.92
2011 Waiskopf N, Shweky I, Lieberman I, Banin U, Soreq H. Quantum dot labeling of butyrylcholinesterase maintains substrate and inhibitor interactions and cell adherence features. Acs Chemical Neuroscience. 2: 141-50. PMID 22778863 DOI: 10.1021/cn1000827  0.92
2011 Gilboa-Geffen A, Wolf Y, Hanin G, Melamed-Book N, Pick M, Bennett ER, Greenberg DS, Lester S, Rischmueller M, Soreq H. Activation of the alternative NFκB pathway improves disease symptoms in a model of Sjogren's syndrome. Plos One. 6: e28727. PMID 22174879 DOI: 10.1371/journal.pone.0028727  0.92
2011 Hanin G, Soreq H. Cholinesterase-Targeting microRNAs Identified in silico Affect Specific Biological Processes. Frontiers in Molecular Neuroscience. 4: 28. PMID 22007158 DOI: 10.3389/fnmol.2011.00028  0.44
2011 Shenhar-Tsarfaty S, Ben-Assayag E, Berliner S, Bornstein NM, Soreq H. Letter by Shenhar-Tsarfaty et al regarding article, "Autonomic shift and increased susceptibility to infections after acute intracerebral hemorrhage". Stroke; a Journal of Cerebral Circulation. 42: e559. PMID 21868734 DOI: 10.1161/STROKEAHA.111.627448  0.92
2011 Soreq H, Wolf Y. NeurimmiRs: microRNAs in the neuroimmune interface. Trends in Molecular Medicine. 17: 548-55. PMID 21813326 DOI: 10.1016/j.molmed.2011.06.009  0.92
2011 Berg RM, Soreq H, Møller K. Effects of physostigmine on microcirculatory alterations during experimental endotoxemia. Shock (Augusta, Ga.). 35: 537-8; author reply . PMID 21499071 DOI: 10.1097/SHK.0b013e318207dd20  0.92
2011 Baselga J, Brasseur D, Brodniewicz-Proba T, Celis J, Fernandez-Aviles F, Garaci E, Gasser S, Højgaard L, Jiricny J, Kieny MP, Kuznicki J, Mattaj I, Olauson A, Pitkanan A, Schöler H, ... ... Soreq H, et al. Europe and the century of biomedical discovery and implementation The Lancet. 377: 719-720. PMID 21316098 DOI: 10.1016/S0140-6736(11)60180-3  0.92
2011 Berg RM, Ofek K, Qvist T, Tofteng F, Soreq H, Møller K. Cholinesterase modulations in patients with acute bacterial meningitis. Scandinavian Journal of Clinical and Laboratory Investigation. 71: 350-2. PMID 21303225 DOI: 10.3109/00365513.2011.558107  0.92
2011 Shenhar-Tsarfaty S, Bruck T, Bennett ER, Bravman T, Aassayag EB, Waiskopf N, Rogowski O, Bornstein N, Berliner S, Soreq H. Butyrylcholinesterase interactions with amylin may protect pancreatic cells in metabolic syndrome. Journal of Cellular and Molecular Medicine. 15: 1747-56. PMID 20807286 DOI: 10.1111/j.1582-4934.2010.01165.x  0.92
2011 Ofek K, Hanin G, Gilboa-Geffen A, Berson A, Goll Y, Greenberg DS, Soreq H, Wilton S. Prophylactic oligonucleotide-mediated enhancement of host acetylcholinesterase protects from organophosphate poisoning 2011 Defense Science Research Conference and Expo, Dsr 2011. DOI: 10.1109/DSR.2011.6026854  0.92
2011 Mor I, Soreq H. Cholinergic Toxicity and the Male Reproductive System Reproductive and Developmental Toxicology. 863-870. DOI: 10.1016/B978-0-12-382032-7.10066-9  0.92
2011 Cohen JE, Friedman A, Zimmermann G, Soreq H. Genomic Implications of Anticholinesterase Sensitivities Anticholinesterase Pesticides: Metabolism, Neurotoxicity, and Epidemiology. 19-24. DOI: 10.1002/9780470640500.ch2  0.92
2010 Berson A, Soreq H. It all starts at the ends: multifaceted involvement of C- and N-terminally modified cholinesterases in Alzheimer's disease. Rambam Maimonides Medical Journal. 1: e0014. PMID 23908786 DOI: 10.5041/RMMJ.10014  0.44
2010 Geyer BC, Kannan L, Garnaud PE, Broomfield CA, Cadieux CL, Cherni I, Hodgins SM, Kasten SA, Kelley K, Kilbourne J, Oliver ZP, Otto TC, Puffenberger I, Reeves TE, Robbins N, ... ... Soreq H, et al. Plant-derived human butyrylcholinesterase, but not an organophosphorous-compound hydrolyzing variant thereof, protects rodents against nerve agents. Proceedings of the National Academy of Sciences of the United States of America. 107: 20251-6. PMID 21059932 DOI: 10.1073/pnas.1009021107  0.92
2010 Toiber D, Azkona G, Ben-Ari S, Torán N, Soreq H, Dierssen M. Engineering DYRK1A overdosage yields Down syndrome-characteristic cortical splicing aberrations. Neurobiology of Disease. 40: 348-59. PMID 20600907 DOI: 10.1016/j.nbd.2010.06.011  0.92
2010 Ben Assayag E, Shenhar-Tsarfaty S, Ofek K, Soreq L, Bova I, Shopin L, Berg RM, Berliner S, Shapira I, Bornstein NM, Soreq H. Serum cholinesterase activities distinguish between stroke patients and controls and predict 12-month mortality. Molecular Medicine (Cambridge, Mass.). 16: 278-86. PMID 20464061 DOI: 10.2119/molmed.2010.00015  0.92
2010 Geyer BC, Kannan L, Cherni I, Woods RR, Soreq H, Mor TS. Transgenic plants as a source for the bioscavenging enzyme, human butyrylcholinesterase. Plant Biotechnology Journal. 8: 873-86. PMID 20353404 DOI: 10.1111/j.1467-7652.2010.00515.x  0.92
2010 Greenberg DS, Toiber D, Berson A, Soreq H. Acetylcholinesterase variants in Alzheimer's disease: from neuroprotection to programmed cell death. Neuro-Degenerative Diseases. 7: 60-3. PMID 20173328 DOI: 10.1159/000285507  0.92
2010 Podoly E, Hanin G, Soreq H. Alanine-to-threonine substitutions and amyloid diseases: butyrylcholinesterase as a case study. Chemico-Biological Interactions. 187: 64-71. PMID 20060816 DOI: 10.1016/j.cbi.2010.01.003  0.92
2010 Sifringer M, Brait D, Weichelt U, Zimmerman G, Endesfelder S, Brehmer F, von Haefen C, Friedman A, Soreq H, Bendix I, Gerstner B, Felderhoff-Mueser U. Erythropoietin attenuates hyperoxia-induced oxidative stress in the developing rat brain. Brain, Behavior, and Immunity. 24: 792-9. PMID 19729061 DOI: 10.1016/j.bbi.2009.08.010  0.92
2010 Meerson A, Cacheaux L, Goosens KA, Sapolsky RM, Soreq H, Kaufer D. Changes in brain MicroRNAs contribute to cholinergic stress reactions. Journal of Molecular Neuroscience : Mn. 40: 47-55. PMID 19711202 DOI: 10.1007/s12031-009-9252-1  0.92
2010 Soreq H. Gulf War Syndrome, Psychological and Chemical Stressors Encyclopedia of Stress. 248-254. DOI: 10.1016/B978-012373947-6.00184-7  0.92
2009 Shaked I, Meerson A, Wolf Y, Avni R, Greenberg D, Gilboa-Geffen A, Soreq H. MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. Immunity. 31: 965-73. PMID 20005135 DOI: 10.1016/j.immuni.2009.09.019  0.92
2009 Toiber D, Greenberg DS, Soreq H. Pro-apoptotic protein-protein interactions of the extended N-AChE terminus. Journal of Neural Transmission (Vienna, Austria : 1996). 116: 1435-42. PMID 19533292 DOI: 10.1007/s00702-009-0249-2  0.92
2009 Podoly E, Shalev DE, Shenhar-Tsarfaty S, Bennett ER, Ben Assayag E, Wilgus H, Livnah O, Soreq H. The butyrylcholinesterase K variant confers structurally derived risks for Alzheimer pathology. The Journal of Biological Chemistry. 284: 17170-9. PMID 19383604 DOI: 10.1074/jbc.M109.004952  0.92
2009 Heinrich B, Zhang Z, Raitskin O, Hiller M, Benderska N, Hartmann AM, Bracco L, Elliott D, Ben-Ari S, Soreq H, Sperling J, Sperling R, Stamm S. Heterogeneous nuclear ribonucleoprotein G regulates splice site selection by binding to CC(A/C)-rich regions in pre-mRNA. The Journal of Biological Chemistry. 284: 14303-15. PMID 19282290 DOI: 10.1074/jbc.M901026200  0.92
2009 Karni S, Soreq H, Sharan R. A network-based method for predicting disease-causing genes. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 16: 181-9. PMID 19193144 DOI: 10.1089/cmb.2008.05TT  0.92
2009 Geyer BC, Evron T, Soreq H, Mor TS. Organophosphate intoxication: Molecular consequences, mechanisms and solutions Handbook of Toxicology of Chemical Warfare Agents. 691-717. DOI: 10.1016/B978-012374484-5.00046-8  0.92
2009 Berson A, Hanan M, Soreq H. Stress and Neurodegeneration: Adding Insult to Injury? Stress - From Molecules to Behavior: a Comprehensive Analysis of the Neurobiology of Stress Responses. 297-316. DOI: 10.1002/9783527628346.ch16  0.92
2009 Friedman A, Kaufer D, Soreq H. Preface Stress - From Molecules to Behavior: a Comprehensive Analysis of the Neurobiology of Stress Responses. XV-XVII. DOI: 10.1002/9783527628346  0.92
2008 Shaked I, Zimmerman G, Soreq H. Stress-induced alternative splicing modulations in brain and periphery: acetylcholinesterase as a case study. Annals of the New York Academy of Sciences. 1148: 269-81. PMID 19120119 DOI: 10.1196/annals.1410.001  0.92
2008 Salas R, Main A, Gangitano DA, Zimmerman G, Ben-Ari S, Soreq H, De Biasi M. Nicotine relieves anxiogenic-like behavior in mice that overexpress the read-through variant of acetylcholinesterase but not in wild-type mice. Molecular Pharmacology. 74: 1641-8. PMID 18776044 DOI: 10.1124/mol.108.048454  0.92
2008 Toiber D, Berson A, Greenberg D, Melamed-Book N, Diamant S, Soreq H. N-acetylcholinesterase-induced apoptosis in Alzheimer's disease. Plos One. 3: e3108. PMID 18769671 DOI: 10.1371/journal.pone.0003108  0.92
2008 Soreq L, Israel Z, Bergman H, Soreq H. Advanced microarray analysis highlights modified neuro-immune signaling in nucleated blood cells from Parkinson's disease patients. Journal of Neuroimmunology. 201: 227-36. PMID 18692253 DOI: 10.1016/j.jneuroim.2008.06.019  0.92
2008 Mor I, Bruck T, Greenberg D, Berson A, Schreiber L, Grisaru D, Soreq H. Alternate AChE-R variants facilitate cellular metabolic activity and resistance to genotoxic stress through enolase and RACK1 interactions. Chemico-Biological Interactions. 175: 11-21. PMID 18572152 DOI: 10.1016/j.cbi.2008.05.019  0.92
2008 Sussman JD, Argov Z, McKee D, Hazum E, Brawer S, Soreq H. Antisense treatment for myasthenia gravis: experience with monarsen. Annals of the New York Academy of Sciences. 1132: 283-90. PMID 18567879 DOI: 10.1196/annals.1405.022  0.92
2008 Soreq L, Gilboa-Geffen A, Berrih-Aknin S, Lacoste P, Darvasi A, Soreq E, Bergman H, Soreq H. Identifying alternative hyper-splicing signatures in MG-thymoma by exon arrays. Plos One. 3: e2392. PMID 18545673 DOI: 10.1371/journal.pone.0002392  0.92
2008 Soreq H, Gazit E. The structural basis of amyloid formation. Current Alzheimer Research. 5: 232. PMID 18537539 DOI: 10.2174/156720508784533349  0.92
2008 Zimmerman G, Njunting M, Ivens S, Tolner EA, Tolner E, Behrens CJ, Gross M, Soreq H, Heinemann U, Friedman A. Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats. The European Journal of Neuroscience. 27: 965-75. PMID 18333967 DOI: 10.1111/j.1460-9568.2008.06070.x  0.92
2008 Podoly E, Bruck T, Diamant S, Melamed-Book N, Weiss A, Huang Y, Livnah O, Langermann S, Wilgus H, Soreq H. Human recombinant butyrylcholinesterase purified from the milk of transgenic goats interacts with beta-amyloid fibrils and suppresses their formation in vitro. Neuro-Degenerative Diseases. 5: 232-6. PMID 18322399 DOI: 10.1159/000113711  0.92
2008 Adamec R, Head D, Soreq H, Blundell J. The role of the read through variant of acetylcholinesterase in anxiogenic effects of predator stress in mice. Behavioural Brain Research. 189: 180-90. PMID 18243359 DOI: 10.1016/j.bbr.2007.12.023  0.92
2008 Soreq H. Introduction: cholinesterases, from molecular complexity to non-hydrolytic functions. The Febs Journal. 275: 603. PMID 18205835 DOI: 10.1111/j.1742-4658.2007.06234.x  0.92
2008 Mor I, Sklan EH, Podoly E, Pick M, Kirschner M, Yogev L, Bar-Sheshet Itach S, Schreiber L, Geyer B, Mor T, Grisaru D, Soreq H. Acetylcholinesterase-R increases germ cell apoptosis but enhances sperm motility. Journal of Cellular and Molecular Medicine. 12: 479-95. PMID 18194455 DOI: 10.1111/j.1582-4934.2008.00231.x  0.92
2008 Berson A, Knobloch M, Hanan M, Diamant S, Sharoni M, Schuppli D, Geyer BC, Ravid R, Mor TS, Nitsch RM, Soreq H. Changes in readthrough acetylcholinesterase expression modulate amyloid-beta pathology. Brain : a Journal of Neurology. 131: 109-19. PMID 18056160 DOI: 10.1093/brain/awm276  0.92
2008 Cohen JE, Zimmerman G, Melamed-Book N, Friedman A, Dori A, Soreq H. Transgenic inactivation of acetylcholinesterase impairs homeostasis in mouse hippocampal granule cells. Hippocampus. 18: 182-92. PMID 17960645 DOI: 10.1002/hipo.20381  0.92
2008 Shapira-Lichter I, Beilin B, Ofek K, Bessler H, Gruberger M, Shavit Y, Seror D, Grinevich G, Posner E, Reichenberg A, Soreq H, Yirmiya R. Cytokines and cholinergic signals co-modulate surgical stress-induced changes in mood and memory. Brain, Behavior, and Immunity. 22: 388-98. PMID 17959355 DOI: 10.1016/j.bbi.2007.09.006  0.92
2008 Zimmerman G, Njunting M, Ivens S, Tolner EA, Behrens CJ, Gross M, Soreq H, Heinemann U, Friedman A. Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats (European Journal of Neuroscience (2008) 27, (965-975)) European Journal of Neuroscience. 28: 418. DOI: 10.1111/j.1460-9568.2008.06396.x  0.92
2007 Concato J, Aslan M, Palmisano MM, Doebbeling CC, Peduzzi P, Ofek K, Soreq H, Doebbeling B. Acetylcholinesterase activity in veterans of the first Gulf War. Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 55: 360-7. PMID 18062897 DOI: 10.2310/6650.2007.00016  0.92
2007 Argov Z, McKee D, Agus S, Brawer S, Shlomowitz N, Yoseph OB, Soreq H, Sussman JD. Treatment of human myasthenia gravis with oral antisense suppression of acetylcholinesterase. Neurology. 69: 699-700. PMID 17698793 DOI: 10.1212/01.wnl.0000267884.39468.7a  0.92
2007 Ofek K, Krabbe KS, Evron T, Debecco M, Nielsen AR, Brunnsgaad H, Yirmiya R, Soreq H, Pedersen BK. Cholinergic status modulations in human volunteers under acute inflammation. Journal of Molecular Medicine (Berlin, Germany). 85: 1239-51. PMID 17657467 DOI: 10.1007/s00109-007-0226-x  0.92
2007 Farchi N, Ofek K, Podoly E, Dong H, Xiang YY, Diamant S, Livnah O, Li J, Hochner B, Lu WY, Soreq H. Peripheral site acetylcholinesterase blockade induces RACK1-associated neuronal remodeling. Neuro-Degenerative Diseases. 4: 171-84. PMID 17596712 DOI: 10.1159/000101842  0.92
2007 Geyer BC, Fletcher SP, Griffin TA, Lopker MJ, Soreq H, Mor TS. Translational control of recombinant human acetylcholinesterase accumulation in plants. Bmc Biotechnology. 7: 27. PMID 17537261 DOI: 10.1186/1472-6750-7-27  0.92
2007 Perry C, Pick M, Podoly E, Gilboa-Geffen A, Zimmerman G, Sklan EH, Ben-Shaul Y, Diamant S, Soreq H. Acetylcholinesterase/C terminal binding protein interactions modify Ikaros functions, causing T lymphopenia. Leukemia. 21: 1472-80. PMID 17476278 DOI: 10.1038/sj.leu.2404722  0.92
2007 Evron T, Geyer BC, Cherni I, Muralidharan M, Kilbourne J, Fletcher SP, Soreq H, Mor TS. Plant-derived human acetylcholinesterase-R provides protection from lethal organophosphate poisoning and its chronic aftermath. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 2961-9. PMID 17475919 DOI: 10.1096/fj.07-8112com  0.92
2007 Dori A, Ifergane G, Saar-Levy T, Bersudsky M, Mor I, Soreq H, Wirguin I. Readthrough acetylcholinesterase in inflammation-associated neuropathies. Life Sciences. 80: 2369-74. PMID 17379257 DOI: 10.1016/j.lfs.2007.02.011  0.92
2007 Kehat R, Zemel E, Cuenca N, Evron T, Toiber D, Loewenstein A, Soreq H, Perlman I. A novel isoform of acetylcholinesterase exacerbates photoreceptors death after photic stress. Investigative Ophthalmology & Visual Science. 48: 1290-7. PMID 17325175 DOI: 10.1167/iovs.06-0847  0.92
2007 Gilboa-Geffen A, Lacoste PP, Soreq L, Cizeron-Clairac G, Le Panse R, Truffault F, Shaked I, Soreq H, Berrih-Aknin S. The thymic theme of acetylcholinesterase splice variants in myasthenia gravis. Blood. 109: 4383-91. PMID 17272501 DOI: 10.1182/blood-2006-07-033373  0.92
2007 Soreq H, Honigman A. It is all about resolution. Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia). The Febs Journal. 274: 924-7. PMID 17269934 DOI: 10.1111/j.1742-4658.2007.05640.x  0.92
2007 Farchi N, Shoham S, Hochner B, Soreq H. Impaired hippocampal plasticity and errors in cognitive performance in mice with maladaptive AChE splice site selection. The European Journal of Neuroscience. 25: 87-98. PMID 17241270 DOI: 10.1111/j.1460-9568.2006.05249.x  0.92
2007 Evron T, Greenberg D, Mor TS, Soreq H. Adaptive changes in acetylcholinesterase gene expression as mediators of recovery from chemical and biological insults. Toxicology. 233: 97-107. PMID 17005312 DOI: 10.1016/j.tox.2006.08.018  0.92
2006 Zimmerman G, Soreq H. Readthrough acetylcholinesterase: a multifaceted inducer of stress reactions. Journal of Molecular Neuroscience : Mn. 30: 197-200. PMID 17192675 DOI: 10.1385/JMN:30:1:197  0.92
2006 Dori A, Soreq H. Neuromuscular therapeutics by RNA-targeted suppression of ACHE gene expression. Annals of the New York Academy of Sciences. 1082: 77-90. PMID 17145929 DOI: 10.1196/annals.1348.004  0.92
2006 Sklan EH, Berson A, Birikh KR, Gutnick A, Shahar O, Shoham S, Soreq H. Acetylcholinesterase modulates stress-induced motor responses through catalytic and noncatalytic properties. Biological Psychiatry. 60: 741-51. PMID 16904653 DOI: 10.1016/j.biopsych.2006.03.080  0.92
2006 Perry C, Soreq H. ACHE gene expression in human brain tumors involves alternative splicing and CREB-induced proliferative signals. The Israel Medical Association Journal : Imaj. 8: 364-5. PMID 16838434  0.92
2006 Ben-Shaul Y, Benmoyal-Segal L, Ben-Ari S, Bergman H, Soreq H. Adaptive acetylcholinesterase splicing patterns attenuate 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. The European Journal of Neuroscience. 23: 2915-22. PMID 16819980 DOI: 10.1111/j.1460-9568.2006.04812.x  0.92
2006 Browne RO, Moyal-Segal LB, Zumsteg D, David Y, Kofman O, Berger A, Soreq H, Friedman A. Coding region paraoxonase polymorphisms dictate accentuated neuronal reactions in chronic, sub-threshold pesticide exposure. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 1733-5. PMID 16807370 DOI: 10.1096/fj.05-5576fje  0.92
2006 Benmoyal-Segal L, Soreq H. Gene-environment interactions in sporadic Parkinson's disease. Journal of Neurochemistry. 97: 1740-55. PMID 16805780 DOI: 10.1111/j.1471-4159.2006.03937.x  0.92
2006 Zimmerman G, Soreq H. Termination and beyond: acetylcholinesterase as a modulator of synaptic transmission. Cell and Tissue Research. 326: 655-69. PMID 16802134 DOI: 10.1007/s00441-006-0239-8  0.92
2006 Diamant S, Podoly E, Friedler A, Ligumsky H, Livnah O, Soreq H. Butyrylcholinesterase attenuates amyloid fibril formation in vitro. Proceedings of the National Academy of Sciences of the United States of America. 103: 8628-33. PMID 16731619 DOI: 10.1073/pnas.0602922103  0.92
2006 Dori A, Soreq H. ARP, the cleavable C-terminal peptide of "readthrough" acetylcholinesterase, promotes neuronal development and plasticity. Journal of Molecular Neuroscience : Mn. 28: 247-55. PMID 16691012 DOI: 10.1385/JMN:28:3:247  0.92
2006 Ben-Ari S, Toiber D, Sas AS, Soreq H, Ben-Shaul Y. Modulated splicing-associated gene expression in P19 cells expressing distinct acetylcholinesterase splice variants. Journal of Neurochemistry. 97: 24-34. PMID 16635247 DOI: 10.1111/j.1471-4159.2006.03725.x  0.92
2006 Meshorer E, Soreq H. Virtues and woes of AChE alternative splicing in stress-related neuropathologies. Trends in Neurosciences. 29: 216-24. PMID 16516310 DOI: 10.1016/j.tins.2006.02.005  0.92
2006 Sklan EH, Podoly E, Soreq H. RACK1 has the nerve to act: structure meets function in the nervous system. Progress in Neurobiology. 78: 117-34. PMID 16457939 DOI: 10.1016/j.pneurobio.2005.12.002  0.92
2006 Pick M, Perry C, Lapidot T, Guimaraes-Sternberg C, Naparstek E, Deutsch V, Soreq H. Stress-induced cholinergic signaling promotes inflammation-associated thrombopoiesis. Blood. 107: 3397-406. PMID 16380450 DOI: 10.1182/blood-2005-08-3240  0.92
2006 Grisaru D, Pick M, Perry C, Sklan EH, Almog R, Goldberg I, Naparstek E, Lessing JB, Soreq H, Deutsch V. Hydrolytic and nonenzymatic functions of acetylcholinesterase comodulate hemopoietic stress responses. Journal of Immunology (Baltimore, Md. : 1950). 176: 27-35. PMID 16365392  0.92
2006 Guimaraes-Sternberg C, Meerson A, Shaked I, Soreq H. MicroRNA modulation of megakaryoblast fate involves cholinergic signaling. Leukemia Research. 30: 583-95. PMID 16249029 DOI: 10.1016/j.leukres.2005.09.005  0.92
2006 González-Ros JM, Encinar JA, Soreq H, Karczmar AG. The XII international symposium on cholinergic mechanisms Journal of Molecular Neuroscience. 30: 1-2. DOI: 10.1385/JMN:30:1:1  0.92
2006 Meshorer E, Biton IE, Ben-Shaul Y, Ben-Ari S, Assaf Y, Soreq H, Cohen Y. Chronic cholinergic imbalances promote brain diffusion and transport abnormalities [2] Faseb Journal. 20: 2425. DOI: 10.1096/fj.06-1105ufm  0.92
2005 Evron T, Moyal-Segal LB, Lamm N, Geffen A, Soreq H. RNA-targeted suppression of stress-induced allostasis in primate spinal cord neurons. Neuro-Degenerative Diseases. 2: 16-27. PMID 16908999 DOI: 10.1159/000086427  0.92
2005 Muralidharan M, Soreq H, Mor TS. Characterizing pea acetylcholinesterase. Chemico-Biological Interactions. 157: 406-7. PMID 16429548 DOI: 10.1016/j.cbi.2005.10.077  0.92
2005 Salmon A, Erb C, Meshorer E, Ginzberg D, Adani Y, Rabinovitz I, Amitai G, Soreq H. Muscarinic modulations of neuronal anticholinesterase responses. Chemico-Biological Interactions. 157: 105-13. PMID 16289123 DOI: 10.1016/j.cbi.2005.10.015  0.92
2005 Geyer BC, Muralidharan M, Cherni I, Doran J, Fletcher SP, Evron T, Soreq H, Mor TS. Purification of transgenic plant-derived recombinant human acetylcholinesterase-R. Chemico-Biological Interactions. 157: 331-4. PMID 16269140 DOI: 10.1016/j.cbi.2005.10.097  0.92
2005 Toiber D, Soreq H. Cellular stress reactions as putative cholinergic links in Alzheimer's disease. Neurochemical Research. 30: 909-19. PMID 16187225 DOI: 10.1007/s11064-005-6963-8  0.92
2005 Meshorer E, Bryk B, Toiber D, Cohen J, Podoly E, Dori A, Soreq H. SC35 promotes sustainable stress-induced alternative splicing of neuronal acetylcholinesterase mRNA. Molecular Psychiatry. 10: 985-97. PMID 16116489 DOI: 10.1038/sj.mp.4001735  0.92
2005 Rees TM, Berson A, Sklan EH, Younkin L, Younkin S, Brimijoin S, Soreq H. Memory deficits correlating with acetylcholinesterase splice shift and amyloid burden in doubly transgenic mice. Current Alzheimer Research. 2: 291-300. PMID 15974894 DOI: 10.2174/1567205054367847  0.92
2005 Meshorer E, Biton IE, Ben-Shaul Y, Ben-Ari S, Assaf Y, Soreq H, Cohen Y. Chronic cholinergic imbalances promote brain diffusion and transport abnormalities. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 910-22. PMID 15923401 DOI: 10.1096/fj.04-2957com  0.92
2005 Pollak Y, Gilboa A, Ben-Menachem O, Ben-Hur T, Soreq H, Yirmiya R. Acetylcholinesterase inhibitors reduce brain and blood interleukin-1beta production. Annals of Neurology. 57: 741-5. PMID 15852394 DOI: 10.1002/ana.20454  0.92
2005 Dori A, Cohen J, Silverman WF, Pollack Y, Soreq H. Functional manipulations of acetylcholinesterase splice variants highlight alternative splicing contributions to murine neocortical development. Cerebral Cortex (New York, N.Y. : 1991). 15: 419-30. PMID 15749986 DOI: 10.1093/cercor/bhh145  0.92
2005 Bryk B, BenMoyal-Segal L, Podoly E, Livnah O, Eisenkraft A, Luria S, Cohen A, Yehezkelli Y, Hourvitz A, Soreq H. Inherited and acquired interactions between ACHE and PON1 polymorphisms modulate plasma acetylcholinesterase and paraoxonase activities. Journal of Neurochemistry. 92: 1216-27. PMID 15715671 DOI: 10.1111/j.1471-4159.2004.02959.x  0.92
2005 Stamm S, Ben-Ari S, Rafalska I, Tang Y, Zhang Z, Toiber D, Thanaraj TA, Soreq H. Function of alternative splicing. Gene. 344: 1-20. PMID 15656968 DOI: 10.1016/j.gene.2004.10.022  0.92
2005 Benmoyal-Segal L, Vander T, Shifman S, Bryk B, Ebstein RP, Marcus EL, Stessman J, Darvasi A, Herishanu Y, Friedman A, Soreq H. Acetylcholinesterase/paraoxonase interactions increase the risk of insecticide-induced Parkinson's disease. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 452-4. PMID 15629887 DOI: 10.1096/fj.04-2106fje  0.92
2005 Ben-Shaul Y, Bergman H, Soreq H. Identifying subtle interrelated changes in functional gene categories using continuous measures of gene expression. Bioinformatics (Oxford, England). 21: 1129-37. PMID 15550480 DOI: 10.1093/bioinformatics/bti149  0.92
2005 Soreq H, Yirmiya R, Cohen O, Glick D. Chapter 4.10 Acetylcholinesterase as a window onto stress responses Techniques in the Behavioral and Neural Sciences. 15: 585-608. DOI: 10.1016/S0921-0709(05)80032-X  0.92
2004 Fletcher SP, Geyer BC, Smith A, Evron T, Joshi L, Soreq H, Mor TS. Tissue distribution of cholinesterases and anticholinesterases in native and transgenic tomato plants. Plant Molecular Biology. 55: 33-43. PMID 15604663 DOI: 10.1007/s11103-004-0394-9  0.92
2004 Dong H, Xiang YY, Farchi N, Ju W, Wu Y, Chen L, Wang Y, Hochner B, Yang B, Soreq H, Lu WY. Excessive expression of acetylcholinesterase impairs glutamatergic synaptogenesis in hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8950-60. PMID 15483114 DOI: 10.1523/JNEUROSCI.2106-04.2004  0.92
2004 Pick M, Flores-Flores C, Grisaru D, Shochat S, Deutsch V, Soreq H. Blood-cell-specific acetylcholinesterase splice variations under changing stimuli. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 22: 523-31. PMID 15465282 DOI: 10.1016/j.ijdevneu.2004.07.016  0.92
2004 Pick M, Flores-Flores C, Soreq H. From brain to blood: alternative splicing evidence for the cholinergic basis of Mammalian stress responses. Annals of the New York Academy of Sciences. 1018: 85-98. PMID 15240356 DOI: 10.1196/annals.1296.010  0.92
2004 Perry C, Soreq H. Organophosphate risk of leukemogenesis. Leukemia Research. 28: 905-6. PMID 15234565 DOI: 10.1016/j.leukres.2004.02.002  0.92
2004 Perry C, Sklan EH, Soreq H. CREB regulates AChE-R-induced proliferation of human glioblastoma cells. Neoplasia (New York, N.Y.). 6: 279-86. PMID 15153340 DOI: 10.1593/neo.3424  0.92
2004 Meshorer E, Toiber D, Zurel D, Sahly I, Dori A, Cagnano E, Schreiber L, Grisaru D, Tronche F, Soreq H. Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products. The Journal of Biological Chemistry. 279: 29740-51. PMID 15123727 DOI: 10.1074/jbc.M402752200  0.92
2004 Sklan EH, Lowenthal A, Korner M, Ritov Y, Landers DM, Rankinen T, Bouchard C, Leon AS, Rice T, Rao DC, Wilmore JH, Skinner JS, Soreq H. Acetylcholinesterase/paraoxonase genotype and expression predict anxiety scores in Health, Risk Factors, Exercise Training, and Genetics study. Proceedings of the National Academy of Sciences of the United States of America. 101: 5512-7. PMID 15060281 DOI: 10.1073/pnas.0307659101  0.92
2004 Darreh-Shori T, Hellström-Lindahl E, Flores-Flores C, Guan ZZ, Soreq H, Nordberg A. Long-lasting acetylcholinesterase splice variations in anticholinesterase-treated Alzheimer's disease patients. Journal of Neurochemistry. 88: 1102-13. PMID 15009666 DOI: 10.1046/j.1471-4159.2003.02230.x  0.92
2004 Nijholt I, Farchi N, Kye M, Sklan EH, Shoham S, Verbeure B, Owen D, Hochner B, Spiess J, Soreq H, Blank T. Stress-induced alternative splicing of acetylcholinesterase results in enhanced fear memory and long-term potentiation. Molecular Psychiatry. 9: 174-83. PMID 14581933 DOI: 10.1038/sj.mp.4001446  0.92
2003 Cohen O, Reichenberg A, Perry C, Ginzberg D, Pollmächer T, Soreq H, Yirmiya R. Endotoxin-induced changes in human working and declarative memory associate with cleavage of plasma "readthrough" acetylcholinesterase. Journal of Molecular Neuroscience : Mn. 21: 199-212. PMID 14645987 DOI: 10.1385/JMN:21:3:199  0.92
2003 Rees T, Hammond PI, Soreq H, Younkin S, Brimijoin S. Acetylcholinesterase promotes beta-amyloid plaques in cerebral cortex. Neurobiology of Aging. 24: 777-87. PMID 12927760 DOI: 10.1016/S0197-4580(02)00230-0  0.92
2003 Glick D, Soreq H. Ethics, public policy and behavioral genetics. The Israel Medical Association Journal : Imaj. 5: 83-6. PMID 12674653  0.92
2003 Brenner T, Hamra-Amitay Y, Evron T, Boneva N, Seidman S, Soreq H. The role of readthrough acetylcholinesterase in the pathophysiology of myasthenia gravis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 214-22. PMID 12554700 DOI: 10.1096/fj.02-0609com  0.92
2003 Birikh KR, Sklan EH, Shoham S, Soreq H. Interaction of "readthrough" acetylcholinesterase with RACK1 and PKCbeta II correlates with intensified fear-induced conflict behavior. Proceedings of the National Academy of Sciences of the United States of America. 100: 283-8. PMID 12509514 DOI: 10.1073/pnas.0135647100  0.92
2003 Farchi N, Soreq H, Hochner B. Chronic acetylcholinesterase overexpression induces multilevelled aberrations in mouse neuromuscular physiology. The Journal of Physiology. 546: 165-73. PMID 12509486 DOI: 10.1113/jphysiol.2002.030841  0.92
2003 Sczakiel G, Soreq H, Greiner B, Gekeler V, Lemaitre M, Park WS, Miyano-Kurosaki N, Hayafune M, Takaku H, Borkhardt A, Sproat BS, Nielsen PE, Hartmann G, Endres S, Heckelsmiller K, et al. Workshop: Therapeutic oligonucleotides in drug development Arzneimittel-Forschung/Drug Research. 53: 449-466.  0.92
2002 Meshorer E, Soreq H. Pre-mRNA splicing modulations in senescence. Aging Cell. 1: 10-6. PMID 12882348  0.92
2002 Stoilov P, Meshorer E, Gencheva M, Glick D, Soreq H, Stamm S. Defects in pre-mRNA processing as causes of and predisposition to diseases. Dna and Cell Biology. 21: 803-18. PMID 12489991 DOI: 10.1089/104454902320908450  0.92
2002 Perry C, Sklan EH, Birikh K, Shapira M, Trejo L, Eldor A, Soreq H. Complex regulation of acetylcholinesterase gene expression in human brain tumors. Oncogene. 21: 8428-41. PMID 12466963 DOI: 10.1038/sj.onc.1205945  0.92
2002 Flores-Flores C, Nissim A, Shochat S, Soreq H. Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semi-synthetic phage display library. Journal of Neural Transmission. Supplementum. 165-79. PMID 12456061  0.92
2002 Deutsch VR, Pick M, Perry C, Grisaru D, Hemo Y, Golan-Hadari D, Grant A, Eldor A, Soreq H. The stress-associated acetylcholinesterase variant AChE-R is expressed in human CD34(+) hematopoietic progenitors and its C-terminal peptide ARP promotes their proliferation. Experimental Hematology. 30: 1153-61. PMID 12384146 DOI: 10.1016/S0301-472X(02)00900-1  0.92
2002 Cohen O, Erb C, Ginzberg D, Pollak Y, Seidman S, Shoham S, Yirmiya R, Soreq H. Neuronal overexpression of "readthrough" acetylcholinesterase is associated with antisense-suppressible behavioral impairments. Molecular Psychiatry. 7: 874-85. PMID 12232781 DOI: 10.1038/sj.mp.4001103  0.92
2002 Darreh-Shori T, Almkvist O, Guan ZZ, Garlind A, Strandberg B, Svensson AL, Soreq H, Hellström-Lindahl E, Nordberg A. Sustained cholinesterase inhibition in AD patients receiving rivastigmine for 12 months. Neurology. 59: 563-72. PMID 12196650  0.92
2002 Perry C, Soreq H. Transcriptional regulation of erythropoiesis. Fine tuning of combinatorial multi-domain elements. European Journal of Biochemistry / Febs. 269: 3607-18. PMID 12153557 DOI: 10.1046/j.1432-1033.2002.02999.x  0.92
2002 Svedberg MM, Svensson AL, Johnson M, Lee M, Cohen O, Court J, Soreq H, Perry E, Nordberg A. Upregulation of neuronal nicotinic receptor subunits alpha4, beta2, and alpha7 in transgenic mice overexpressing human acetylcholinesterase. Journal of Molecular Neuroscience : Mn. 18: 211-22. PMID 12059039 DOI: 10.1385/JMN:18:3:211  0.92
2002 Meshorer E, Erb C, Gazit R, Pavlovsky L, Kaufer D, Friedman A, Glick D, Ben-Arie N, Soreq H. Alternative splicing and neuritic mRNA translocation under long-term neuronal hypersensitivity. Science (New York, N.Y.). 295: 508-12. PMID 11799248 DOI: 10.1126/science.1066752  0.92
2002 Perry C, Eldor A, Soreq H. Runx1/AML1 in leukemia: disrupted association with diverse protein partners. Leukemia Research. 26: 221-8. PMID 11792409 DOI: 10.1016/S0145-2126(01)00128-X  0.92
2002 Soreq H. Acetylcholinesterase as a window to stress responses Biomedicine and Pharmacotherapy. 56: 211-212. DOI: 10.1016/S0753-3322(02)00179-8  0.92
2001 Grant AD, Shapira M, Soreq H. Genomic dissection reveals locus response to stress for mammalian acetylcholinesterase. Cellular and Molecular Neurobiology. 21: 783-97. PMID 12043848 DOI: 10.1023/A:1015112407079  0.92
2001 Tomkins O, Kaufer D, Korn A, Shelef I, Golan H, Reichenthal E, Soreq H, Friedman A. Frequent blood-brain barrier disruption in the human cerebral cortex. Cellular and Molecular Neurobiology. 21: 675-91. PMID 12043841 DOI: 10.1023/A:1015147920283  0.92
2001 Shapira M, Thompson CK, Soreq H, Robinson GE. Changes in neuronal acetylcholinesterase gene expression and division of labor in honey bee colonies. Journal of Molecular Neuroscience : Mn. 17: 1-12. PMID 11665858 DOI: 10.1385/JMN:17:1:1  0.92
2001 Perry C, Soreq H. The leukemic effect of anticholinesterases. Leukemia Research. 25: 1027-8. PMID 11597740 DOI: 10.1016/S0145-2126(01)00071-6  0.92
2001 Mor TS, Sternfeld M, Soreq H, Arntzen CJ, Mason HS. Expression of recombinant human acetylcholinesterase in transgenic tomato plants. Biotechnology and Bioengineering. 75: 259-66. PMID 11590598 DOI: 10.1002/bit.10012  0.92
2001 Mor I, Grisaru D, Titelbaum L, Evron T, Richler C, Wahrman J, Sternfeld M, Yogev L, Meiri N, Seidman S, Soreq H. Modified testicular expression of stress-associated "readthrough" acetylcholinesterase predicts male infertility. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2039-41. PMID 11511515 DOI: 10.1096/fj.00-0814fje  0.92
2001 Grisaru D, Deutsch V, Shapira M, Pick M, Sternfeld M, Melamed-Book N, Kaufer D, Galyam N, Gait MJ, Owen D, Lessing JB, Eldor A, Soreq H. ARP, a peptide derived from the stress-associated acetylcholinesterase variant, has hematopoietic growth promoting activities. Molecular Medicine (Cambridge, Mass.). 7: 93-105. PMID 11471550  0.92
2001 Erb C, Troost J, Kopf S, Schmitt U, Löffelholz K, Soreq H, Klein J. Compensatory mechanisms enhance hippocampal acetylcholine release in transgenic mice expressing human acetylcholinesterase. Journal of Neurochemistry. 77: 638-46. PMID 11299326 DOI: 10.1046/j.1471-4159.2001.00287.x  0.92
2001 Soreq H, Seidman S. Acetylcholinesterase--new roles for an old actor. Nature Reviews. Neuroscience. 2: 294-302. PMID 11283752 DOI: 10.1038/35067589  0.92
2001 Galyam N, Grisaru D, Grifman M, Melamed-Book N, Eckstein F, Seidman S, Eldor A, Soreq H. Complex host cell responses to antisense suppression of ACHE gene expression. Antisense & Nucleic Acid Drug Development. 11: 51-7. PMID 11258621 DOI: 10.1089/108729001750072128  0.92
2000 Shohami E, Kaufer D, Chen Y, Seidman S, Cohen O, Ginzberg D, Melamed-Book N, Yirmiya R, Soreq H. Antisense prevention of neuronal damages following head injury in mice. Journal of Molecular Medicine (Berlin, Germany). 78: 228-36. PMID 10933585  0.92
2000 Soreq H, Seidman S. Anti-sense approach to anticholinesterase therapeutics. The Israel Medical Association Journal : Imaj. 2: 81-5. PMID 10909423  0.92
2000 Shapira M, Grant A, Korner M, Soreq H. Genomic and transcriptional characterization of the human ACHE locus: complex involvement with acquired and inherited diseases. The Israel Medical Association Journal : Imaj. 2: 470-3. PMID 10897240  0.92
2000 Sternfeld M, Shoham S, Klein O, Flores-Flores C, Evron T, Idelson GH, Kitsberg D, Patrick JW, Soreq H. Excess "read-through" acetylcholinesterase attenuates but the "synaptic" variant intensifies neurodeterioration correlates. Proceedings of the National Academy of Sciences of the United States of America. 97: 8647-52. PMID 10890884 DOI: 10.1073/pnas.140004597  0.92
2000 Itskovitz-Eldor J, Schuldiner M, Karsenti D, Eden A, Yanuka O, Amit M, Soreq H, Benvenisty N. Differentiation of human embryonic stem cells into embryoid bodies compromising the three embryonic germ layers. Molecular Medicine (Cambridge, Mass.). 6: 88-95. PMID 10859025  0.92
2000 Lev-Lehman E, Evron T, Broide RS, Meshorer E, Ariel I, Seidman S, Soreq H. Synaptogenesis and myopathy under acetylcholinesterase overexpression. Journal of Molecular Neuroscience : Mn. 14: 93-105. PMID 10854041 DOI: 10.1385/JMN:14:1-2:093  0.92
2000 Shapira M, Tur-Kaspa I, Bosgraaf L, Livni N, Grant AD, Grisaru D, Korner M, Ebstein RP, Soreq H. A transcription-activating polymorphism in the ACHE promoter associated with acute sensitivity to anti-acetylcholinesterases. Human Molecular Genetics. 9: 1273-81. PMID 10814709  0.92
2000 Perry E, Martin-Ruiz C, Lee M, Griffiths M, Johnson M, Piggott M, Haroutunian V, Buxbaum JD, Nãsland J, Davis K, Gotti C, Clementi F, Tzartos S, Cohen O, Soreq H, et al. Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases. European Journal of Pharmacology. 393: 215-22. PMID 10771016 DOI: 10.1016/S0014-2999(00)00064-9  0.92
2000 Shapira M, Grant A, Soreq H. The human ACHE extended promoter. An exceptionally long stress-responding promoter controls the human acetylcholinesterase gene expression Italian Journal of Psychiatry and Behavioural Sciences. 10: 17-21.  0.92
2000 Deutsch V, Pick M, Grisaru D, Shapira M, Seidman S, Melamed-Book N, Soreq H, Eldor A. The stress associated variant of acetylcholinesterase is expressed in CD34+CD38+ and CD38- HPC and its C-terminal peptide modulates hematopoiesis Blood. 96: 118b.  0.92
1999 Kaufer D, Soreq H. Tracking cholinergic pathways from psychological and chemical stressors to variable neurodeterioration paradigms. Current Opinion in Neurology. 12: 739-43. PMID 10676758 DOI: 10.1097/00019052-199912000-00014  0.92
1999 Broide RS, Grifman M, Loewenstein A, Grisaru D, Timberg R, Stone J, Shani M, Patrick JW, Soreq H. Manipulations of ACHE gene expression suggest non-catalytic involvement of acetylcholinesterase in the functioning of mammalian photoreceptors but not in retinal degeneration. Brain Research. Molecular Brain Research. 71: 137-48. PMID 10521568 DOI: 10.1016/S0169-328X(99)00169-2  0.92
1999 Grisaru D, Sternfeld M, Eldor A, Glick D, Soreq H. Structural roles of acetylcholinesterase variants in biology and pathology. European Journal of Biochemistry / Febs. 264: 672-86. PMID 10491113 DOI: 10.1046/j.1432-1327.1999.00693.x  0.52
1999 Seidman S, Eckstein F, Grifman M, Soreq H. Antisense technologies have a future fighting neurodegenerative diseases. Antisense & Nucleic Acid Drug Development. 9: 333-40. PMID 10463077  0.92
1999 Kaufer D, Friedman A, Seidman S, Soreq H. Anticholinesterases induce multigenic transcriptional feedback response suppressing cholinergic neurotransmission. Chemico-Biological Interactions. 119: 349-60. PMID 10421471 DOI: 10.1016/S0009-2797(99)00046-0  0.92
1999 Grisaru D, Lev-Lehman E, Shapira M, Chaikin E, Lessing JB, Eldor A, Eckstein F, Soreq H. Human osteogenesis involves differentiation-dependent increases in the morphogenically active 3' alternative splicing variant of acetylcholinesterase. Molecular and Cellular Biology. 19: 788-95. PMID 9858601  0.92
1998 Shapira M, Seidman S, Livni N, Soreq H. In vivo and in vitro resistance to multiple anticholinesterases in Xenopus laevis tadpoles. Toxicology Letters. 102: 205-9. PMID 10022255 DOI: 10.1016/S0378-4274(98)00308-7  0.92
1998 Grifman M, Galyam N, Seidman S, Soreq H. Functional redundancy of acetylcholinesterase and neuroligin in mammalian neuritogenesis. Proceedings of the National Academy of Sciences of the United States of America. 95: 13935-40. PMID 9811904  0.8
1998 Friedman A, Kaufer D, Pavlovsky L, Soreq H. Cholinergic excitation induces activity-dependent electrophysiological and transcriptional responses in hippocampal slices. Journal of Physiology, Paris. 92: 329-35. PMID 9789832 DOI: 10.1016/S0928-4257(98)80042-9  0.92
1998 Sternfeld M, Patrick JD, Soreq H. Position effect variegations and brain-specific silencing in transgenic mice overexpressing human acetylcholinesterase variants. Journal of Physiology, Paris. 92: 249-55. PMID 9789818 DOI: 10.1016/S0928-4257(98)80028-4  0.52
1998 Andres C, Seidman S, Beeri R, Timberg R, Soreq H. Transgenic acetylcholinesterase induces enlargement of murine neuromuscular junctions but leaves spinal cord synapses intact. Neurochemistry International. 32: 449-56. PMID 9676744  0.8
1998 Kaufer D, Friedman A, Seidman S, Soreq H. Acute stress facilitates long-lasting changes in cholinergic gene expression. Nature. 393: 373-7. PMID 9620801 DOI: 10.1038/30741  0.92
1998 Sternfeld M, Ming G, Song H, Sela K, Timberg R, Poo M, Soreq H. Acetylcholinesterase enhances neurite growth and synapse development through alternative contributions of its hydrolytic capacity, core protein, and variable C termini. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 1240-9. PMID 9454834  0.52
1997 Grifman M, Arbel A, Ginzberg D, Glick D, Elgavish S, Shaanan B, Soreq H. In vitro phosphorylation of acetylcholinesterase at non-consensus protein kinase A sites enhances the rate of acetylcholine hydrolysis. Brain Research. Molecular Brain Research. 51: 179-87. PMID 9427520  0.36
1997 Beeri R, Le Novère N, Mervis R, Huberman T, Grauer E, Changeux JP, Soreq H. Enhanced hemicholinium binding and attenuated dendrite branching in cognitively impaired acetylcholinesterase-transgenic mice. Journal of Neurochemistry. 69: 2441-51. PMID 9375677  0.92
1997 Grifman M, Soreq H. Differentiation intensifies the susceptibility of pheochromocytoma cells to antisense oligodeoxynucleotide-dependent suppression of acetylcholinesterase activity. Antisense & Nucleic Acid Drug Development. 7: 351-9. PMID 9303187  0.36
1997 Andres C, Beeri R, Friedman A, Lev-Lehman E, Henis S, Timberg R, Shani M, Soreq H. Acetylcholinesterase-transgenic mice display embryonic modulations in spinal cord choline acetyltransferase and neurexin Ibeta gene expression followed by late-onset neuromotor deterioration. Proceedings of the National Academy of Sciences of the United States of America. 94: 8173-8. PMID 9223334 DOI: 10.1073/pnas.94.15.8173  0.92
1997 Sternfeld M, Rachmilewitz J, Loewenstein-Lichtenstein Y, Andres C, Timberg R, Ben-Ari S, Glick C, Soreq H, Zakut H. Normal and atypical butyrylcholinesterases in placental development, function, and malfunction. Cellular and Molecular Neurobiology. 17: 315-32. PMID 9187488 DOI: 10.1023/A:1026394302076  0.52
1997 Birikh KR, Berlin YA, Soreq H, Eckstein F. Probing accessible sites for ribozymes on human acetylcholinesterase RNA. Rna (New York, N.Y.). 3: 429-37. PMID 9085849  0.92
1997 Broide RS, Grifman M, Shapira M, Ginzberg D, Soreq H. Genetic manipulations of cholinergic communication reveal trans-acting control mechanisms over acetylcholine receptors. Journal of Receptor and Signal Transduction Research. 17: 279-91. PMID 9029496 DOI: 10.3109/10799899709036609  0.92
1996 Andres C, Beeri R, Huberman T, Shani M, Soreq H. Cholinergic drug resistance and impaired spatial learning in transgenic mice overexpressing human brain acetylcholinesterase. Progress in Brain Research. 109: 265-72. PMID 9009715  0.92
1996 Loewenstein-Lichtenstein Y, Glick D, Gluzman N, Sternfeld M, Zakut H, Soreq H. Overlapping drug interaction sites of human butyrylcholinesterase dissected by site-directed mutagenesis. Molecular Pharmacology. 50: 1423-31. PMID 8967962  0.52
1996 Friedman A, Kaufer D, Shemer J, Hendler I, Soreq H, Tur-Kaspa I. Pyridostigmine brain penetration under stress enhances neuronal excitability and induces early immediate transcriptional response. Nature Medicine. 2: 1382-5. PMID 8946841 DOI: 10.1038/nm1296-1382  0.92
1996 Karpel R, Sternfeld M, Ginzberg D, Guhl E, Graessmann A, Soreq H. Overexpression of alternative human acetylcholinesterase forms modulates process extensions in cultured glioma cells. Journal of Neurochemistry. 66: 114-23. PMID 8522942  0.52
1995 Beeri R, Andres C, Lev-Lehman E, Timberg R, Huberman T, Shani M, Soreq H. Transgenic expression of human acetylcholinesterase induces progressive cognitive deterioration in mice. Current Biology : Cb. 5: 1063-71. PMID 8542283 DOI: 10.1016/S0960-9822(95)00211-9  0.92
1995 Seidman S, Sternfeld M, Ben Aziz-Aloya R, Timberg R, Kaufer-Nachum D, Soreq H. Synaptic and epidermal accumulations of human acetylcholinesterase are encoded by alternative 3'-terminal exons. Molecular and Cellular Biology. 15: 2993-3002. PMID 7760797  0.8
1995 Schwarz M, Glick D, Loewenstein Y, Soreq H. Engineering of human cholinesterases explains and predicts diverse consequences of administration of various drugs and poisons. Pharmacology & Therapeutics. 67: 283-322. PMID 7494866 DOI: 10.1016/0163-7258(95)00019-D  0.92
1994 Karpel R, Ben Aziz-Aloya R, Sternfeld M, Ehrlich G, Ginzberg D, Tarroni P, Clementi F, Zakut H, Soreq H. Expression of three alternative acetylcholinesterase messenger RNAs in human tumor cell lines of different tissue origins. Experimental Cell Research. 210: 268-77. PMID 8299725 DOI: 10.1006/excr.1994.1039  0.52
1994 Gnatt A, Loewenstein Y, Yaron A, Schwarz M, Soreq H. Site-directed mutagenesis of active site residues reveals plasticity of human butyrylcholinesterase in substrate and inhibitor interactions. Journal of Neurochemistry. 62: 749-55. PMID 8294937  0.92
1994 Seidman S, Aziz-Aloya RB, Timberg R, Loewenstein Y, Velan B, Shafferman A, Liao J, Norgaard-Pedersen B, Brodbeck U, Soreq H. Overexpressed monomeric human acetylcholinesterase induces subtle ultrastructural modifications in developing neuromuscular junctions of Xenopus laevis embryos. Journal of Neurochemistry. 62: 1670-81. PMID 8158119  0.92
1994 Shapira M, Seidman S, Sternfeld M, Timberg R, Kaufer D, Patrick J, Soreq H. Transgenic engineering of neuromuscular junctions in Xenopus laevis embryos transiently overexpressing key cholinergic proteins. Proceedings of the National Academy of Sciences of the United States of America. 91: 9072-6. PMID 8090771 DOI: 10.1073/pnas.91.19.9072  0.92
1994 Soreq H, Patinkin D, Lev-Lehman E, Grifman M, Ginzberg D, Eckstein F, Zakut H. Antisense oligonucleotide inhibition of acetylcholinesterase gene expression induces progenitor cell expansion and suppresses hematopoietic apoptosis ex vivo. Proceedings of the National Academy of Sciences of the United States of America. 91: 7907-11. PMID 8058733 DOI: 10.1073/pnas.91.17.7907  0.92
1994 Beeri R, Gnatt A, Lapidot-Lifson Y, Ginzberg D, Shani M, Soreq H, Zakut H. Testicular amplification and impaired transmission of human butyrylcholinesterase cDNA in transgenic mice. Human Reproduction (Oxford, England). 9: 284-92. PMID 8027285  0.92
1994 Ehrlich G, Patinkin D, Ginzberg D, Zakut H, Eckstein F, Soreq H. Use of partially phosphorothioated "antisense" oligodeoxynucleotides for sequence-dependent modulation of hematopoiesis in culture. Antisense Research and Development. 4: 173-83. PMID 7849488  0.92
1994 Lev-Lehman E, el-Tamer A, Yaron A, Grifman M, Ginzberg D, Hanin I, Soreq H. Cholinotoxic effects on acetylcholinesterase gene expression are associated with brain-region specific alterations in G,C-rich transcripts. Brain Research. 661: 75-82. PMID 7834388 DOI: 10.1016/0006-8993(94)91183-5  0.92
1994 Ehrlich G, Ginzberg D, Loewenstein Y, Glick D, Kerem B, Ben-Ari S, Zakut H, Soreq H. Population diversity and distinct haplotype frequencies associated with ACHE and BCHE genes of Israeli Jews from trans-Caucasian Georgia and from Europe. Genomics. 22: 288-95. PMID 7806214 DOI: 10.1006/geno.1994.1386  0.92
1994 Patinkin D, Lev-Lehman E, Zakut H, Eckstein F, Soreq H. Antisense inhibition of butyrylcholinesterase gene expression predicts adverse hematopoietic consequences to cholinesterase inhibitors. Cellular and Molecular Neurobiology. 14: 459-73. PMID 7621507 DOI: 10.1007/BF02088831  0.92
1994 Lev-Lehman E, Ginzberg D, Hornreich G, Ehrlich G, Meshorer A, Eckstein F, Soreq H, Zakut H. Antisense inhibition of acetylcholinesterase gene expression causes transient hematopoietic alterations in vivo. Gene Therapy. 1: 127-35. PMID 7584068  0.92
1993 Ben Aziz-Aloya R, Seidman S, Timberg R, Sternfeld M, Zakut H, Soreq H. Expression of a human acetylcholinesterase promoter-reporter construct in developing neuromuscular junctions of Xenopus embryos. Proceedings of the National Academy of Sciences of the United States of America. 90: 2471-5. PMID 8460160  0.8
1993 Loewenstein Y, Denarie M, Zakut H, Soreq H. Molecular dissection of cholinesterase domains responsible for carbamate toxicity. Chemico-Biological Interactions. 87: 209-16. PMID 8343977 DOI: 10.1016/0009-2797(93)90044-Y  0.92
1993 Loewenstein Y, Gnatt A, Neville LF, Zakut H, Soreq H. Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 17: 905-26. PMID 8278601 DOI: 10.1016/0278-5846(93)90019-O  0.92
1993 Ben Aziz-Aloya R, Sternfeld M, Soreq H. Promoter elements and alternative splicing in the human ACHE gene. Progress in Brain Research. 98: 147-53. PMID 8248502  0.52
1993 Loewenstein Y, Gnatt A, Neville LF, Soreq H. Chimeric human cholinesterase. Identification of interaction sites responsible for recognition of acetyl- or butyrylcholinesterase-specific ligands. Journal of Molecular Biology. 234: 289-96. PMID 8230213 DOI: 10.1006/jmbi.1993.1584  0.92
1992 Lapidot-Lifson Y, Patinkin D, Prody CA, Ehrlich G, Seidman S, Ben-Aziz R, Benseler F, Eckstein F, Zakut H, Soreq H. Cloning and antisense oligodeoxynucleotide inhibition of a human homolog of cdc2 required in hematopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 89: 579-83. PMID 1731328  0.92
1992 Soreq H, Seidman S. Xenopus oocyte microinjection: from gene to protein. Methods in Enzymology. 207: 225-65. PMID 1528119  0.92
1992 Soreq H, Meir R, Zakut H. [Medical aspects and structural implications of cholinesterase inhibitors]. Harefuah. 123: 100-10. PMID 1516859  0.92
1992 Soreq H, Gnatt A, Loewenstein Y, Neville LF. Excavations into the active-site gorge of cholinesterases. Trends in Biochemical Sciences. 17: 353-8. PMID 1412713 DOI: 10.1016/0968-0004(92)90314-Y  0.92
1992 Ehrlich G, Viegas-Pequignot E, Ginzberg D, Sindel L, Soreq H, Zakut H. Mapping the human acetylcholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries. Genomics. 13: 1192-7. PMID 1380483  0.36
1992 Neville LF, Gnatt A, Loewenstein Y, Seidman S, Ehrlich G, Soreq H. Intramolecular relationships in cholinesterases revealed by oocyte expression of site-directed and natural variants of human BCHE. The Embo Journal. 11: 1641-9. PMID 1373381  0.92
1991 Gnatt A, Ginzberg D, Lieman-Hurwitz J, Zamir R, Zakut H, Soreq H. Human acetylcholinesterase and butyrylcholinesterase are encoded by two distinct genes. Cellular and Molecular Neurobiology. 11: 91-104. PMID 2013062 DOI: 10.1007/BF00712802  0.92
1991 Zakut H, Lieman-Hurwitz J, Zamir R, Sindell L, Ginzberg D, Soreq H. Chorionic villus cDNA library displays expression of butyrylcholinesterase: putative genetic disposition for ecological danger. Prenatal Diagnosis. 11: 597-607. PMID 1722578  0.36
1990 Zakut H, Ehrlich G, Ayalon A, Prody CA, Malinger G, Seidman S, Ginzberg D, Kehlenbach R, Soreq H. Acetylcholinesterase and butyrylcholinesterase genes coamplify in primary ovarian carcinomas. The Journal of Clinical Investigation. 86: 900-8. PMID 2394839 DOI: 10.1172/JCI114791  0.8
1990 Gnatt A, Prody CA, Zamir R, Lieman-Hurwitz J, Zakut H, Soreq H. Expression of alternatively terminated unusual human butyrylcholinesterase messenger RNA transcripts, mapping to chromosome 3q26-ter, in nervous system tumors. Cancer Research. 50: 1983-7. PMID 2317787  0.92
1990 Soreq H, Ben-Aziz R, Prody CA, Seidman S, Gnatt A, Neville L, Lieman-Hurwitz J, Lev-Lehman E, Ginzberg D, Lipidot-Lifson Y. Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure. Proceedings of the National Academy of Sciences of the United States of America. 87: 9688-92. PMID 2263619  0.92
1990 Neville LF, Gnatt A, Padan R, Seidman S, Soreq H. Anionic site interactions in human butyrylcholinesterase disrupted by two single point mutations. The Journal of Biological Chemistry. 265: 20735-8. PMID 2249982  0.92
1990 Patinkin D, Seidman S, Eckstein F, Benseler F, Zakut H, Soreq H. Manipulations of cholinesterase gene expression modulate murine megakaryocytopoiesis in vitro. Molecular and Cellular Biology. 10: 6046-50. PMID 2233731  0.8
1990 Neville LF, Gnatt A, Loewenstein Y, Soreq H. Aspartate-70 to glycine substitution confers resistance to naturally occurring and synthetic anionic-site ligands on in-ovo produced human butyrylcholinesterase. Journal of Neuroscience Research. 27: 452-60. PMID 2079709 DOI: 10.1002/jnr.490270404  0.92
1990 Seidman S, Soreq H. Coinjection of Xenopus oocytes with cDNA-produced and native mRNAs: a molecular biological approach to the tissue-specific processing of human cholinesterases. International Review of Neurobiology. 32: 107-39. PMID 2079403 DOI: 10.1016/S0074-7742(08)60581-4  0.92
1989 Lapidot-Lifson Y, Prody CA, Ginzberg D, Meytes D, Zakut H, Soreq H. Coamplification of human acetylcholinesterase and butyrylcholinesterase genes in blood cells: correlation with various leukemias and abnormal megakaryocytopoiesis. Proceedings of the National Academy of Sciences of the United States of America. 86: 4715-9. PMID 2734315  0.36
1989 Soreq H, Seidman S, Dreyfus PA, Zevin-Sonkin D, Zakut H. Expression and tissue-specific assembly of human butyrylcholine esterase in microinjected Xenopus laevis oocytes. The Journal of Biological Chemistry. 264: 10608-13. PMID 2732242  0.8
1989 Dreyfus PA, Seidman S, Pincon-Raymond M, Murawsky M, Rieger F, Schejter E, Zakut H, Soreq H. Tissue-specific processing and polarized compartmentalization of clone-produced cholinesterase in microinjected Xenopus oocytes. Cellular and Molecular Neurobiology. 9: 323-41. PMID 2692828 DOI: 10.1007/BF00711413  0.92
1989 Benvenisty N, Shoshani T, Farkash Y, Soreq H, Reshef L. trans activation of rat phosphoenolpyruvate carboxykinase (GTP) gene expression by micro-coinjection of rat liver mRNA in Xenopus laevis oocytes. Molecular and Cellular Biology. 9: 5244-7. PMID 2601721  0.92
1988 Dreyfus P, Zevin-Sonkin D, Seidman S, Prody C, Zisling R, Zakut H, Soreq H. Cross-homologies and structural differences between human cholinesterases revealed by antibodies against cDNA-produced human butyrylcholinesterase peptides. Journal of Neurochemistry. 51: 1858-67. PMID 2460589  0.8
1987 Soreq H, Gnatt A. Molecular biological search for human genes encoding cholinesterases. Molecular Neurobiology. 1: 47-80. PMID 3077058 DOI: 10.1007/BF02935264  0.92
1987 Prody CA, Zevin-Sonkin D, Gnatt A, Goldberg O, Soreq H. Isolation and characterization of full-length cDNA clones coding for cholinesterase from fetal human tissues. Proceedings of the National Academy of Sciences of the United States of America. 84: 3555-9. PMID 3035536 DOI: 10.1073/pnas.84.11.3555  0.92
1987 Gnatt A, Soreq H. Molecular cloning of human cholinesterase genes: potential applications in neurotoxicology. Progress in Clinical and Biological Research. 253: 111-9. PMID 2963345  0.92
1986 Prody C, Zevin-Sonkin D, Gnatt A, Koch R, Zisling R, Goldberg O, Soreq H. Use of synthetic oligodeoxynucleotide probes for the isolation of a human cholinesterase cDNA clone. Journal of Neuroscience Research. 16: 25-35. PMID 3755763 DOI: 10.1002/jnr.490160105  0.92
1986 Egozi Y, Sokolovsky M, Schejter E, Blatt I, Zakut H, Matzkel A, Soreq H. Divergent regulation of muscarinic binding sites and acetylcholinesterase in discrete regions of the developing human fetal brain. Cellular and Molecular Neurobiology. 6: 55-70. PMID 3719620 DOI: 10.1007/BF00742976  0.92
1986 Dziegielewska KM, Saunders NR, Schejter EJ, Zakut H, Zevin-Sonkin D, Zisling R, Soreq H. Synthesis of plasma proteins in fetal, adult, and neoplastic human brain tissue. Developmental Biology. 115: 93-104. PMID 2422074 DOI: 10.1016/0012-1606(86)90231-9  0.92
1985 Zakut H, Matzkel A, Schejter E, Avni A, Soreq H. Polymorphism of acetylcholinesterase in discrete regions of the developing human fetal brain. Journal of Neurochemistry. 45: 382-9. PMID 4009167 DOI: 10.1111/j.1471-4159.1985.tb03999.x  0.92
1985 Soreq H, Zevin-Sonkin D, Avni A, Hall LM, Spierer P. A human acetylcholinesterase gene identified by homology to the Ace region of Drosophila. Proceedings of the National Academy of Sciences of the United States of America. 82: 1827-31. PMID 3856864 DOI: 10.1073/pnas.82.6.1827  0.92
1985 Libermann TA, Nusbaum HR, Razon N, Kris R, Lax I, Soreq H, Whittle N, Waterfield MD, Ullrich A, Schlessinger J. Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin. Nature. 313: 144-7. PMID 2981413 DOI: 10.1038/313144a0  0.92
1984 Soreq H, Zevin-Sonkin D, Razon N. Expression of cholinesterase gene(s) in human brain tissues: translational evidence for multiple mRNA species. The Embo Journal. 3: 1371-5. PMID 6745236  0.92
1984 Razon N, Soreq H, Roth E, Bartal A, Silman I. Characterization of activities and forms of cholinesterases in human primary brain tumors. Experimental Neurology. 84: 681-95. PMID 6723888 DOI: 10.1016/0014-4886(84)90215-2  0.92
1984 Gurwitz D, Razon N, Sokolovsky M, Soreq H. Expression of muscarinic binding sites in primary human brain tumors. Brain Research. 316: 61-70. PMID 6329477 DOI: 10.1016/0165-3806(84)90009-9  0.92
1984 Libermann TA, Razon N, Bartal AD, Yarden Y, Schlessinger J, Soreq H. Expression of epidermal growth factor receptors in human brain tumors. Cancer Research. 44: 753-60. PMID 6318976  0.92
1983 Soreq H, Safran A, Eliyahu D. Modified composition of major ontogenetically regulated mRNAs and proteins in the cerebellum of old and of staggerer mice. Brain Research. 312: 73-82. PMID 6652509  0.92
1983 Soreq H, Miskin R, Zutra A, Littauer UZ. Modulation in the levels and localization of plasminogen activator in differentiating neuroblastoma cells. Brain Research. 283: 257-69. PMID 6133597 DOI: 10.1016/0165-3806(83)90182-7  0.92
1982 Soreq H, Gurwitz D, Eliyahu D, Sokolovsky M. Altered ontogenesis of muscarinic receptors in agranular cerebellar cortex. Journal of Neurochemistry. 39: 756-63. PMID 7097282  0.92
1982 Littauer UZ, Soreq H. The regulatory function of poly(A) and adjacent 3' sequences in translated RNA. Progress in Nucleic Acid Research and Molecular Biology. 27: 53-83. PMID 7048421 DOI: 10.1016/S0079-6603(08)60597-8  0.92
1982 Eliyahu D, Soreq H. Degranulation of rat cerebellum induces selective variations in gene expression. Journal of Neurochemistry. 38: 313-21. PMID 6180135 DOI: 10.1111/j.1471-4159.1982.tb08631.x  0.92
1980 Soreq H, Harpold M, Wilson M, Darnell JE. Rate of synthesis and concentration of specific mRNA sequences in cultured Chinese hamster ovary cells compared to liver cells. Biochemical and Biophysical Research Communications. 92: 485-91. PMID 7356477  0.52
1979 Soreq H, Harpold M, Evans R, Darnell JE, Bancroft FC. Rat growth hormone gene: intervening sequences separate the mRNA regions. Nucleic Acids Research. 6: 2471-82. PMID 461195  0.52
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