| Year |
Citation |
Score |
| 2022 |
Orellana EA, Siegal E, Gregory RI. tRNA dysregulation and disease. Nature Reviews. Genetics. PMID 35681060 DOI: 10.1038/s41576-022-00501-9 |
0.321 |
|
| 2021 |
Cui Y, Lyu X, Ding L, Ke L, Yang D, Pirouz M, Qi Y, Ong J, Gao G, Du P, Gregory RI. Global miRNA dosage control of embryonic germ layer specification. Nature. PMID 33953397 DOI: 10.1038/s41586-021-03524-0 |
0.406 |
|
| 2020 |
Foster DJ, Chang HM, Haswell JR, Gregory RI, Slack FJ. TRIM71 binds to IMP1 and is capable of positive and negative regulation of target RNAs. Cell Cycle (Georgetown, Tex.). 1-13. PMID 32816599 DOI: 10.1080/15384101.2020.1804232 |
0.374 |
|
| 2020 |
Pirouz M, Wang CH, Liu Q, Ebrahimi AG, Shamsi F, Tseng YH, Gregory RI. The Perlman syndrome DIS3L2 exoribonuclease safeguards endoplasmic reticulum-targeted mRNA translation and calcium ion homeostasis. Nature Communications. 11: 2619. PMID 32457326 DOI: 10.1038/S41467-020-16418-Y |
0.38 |
|
| 2020 |
Liu Q, Shvarts T, Sliz P, Gregory RI. RiboToolkit: an integrated platform for analysis and annotation of ribosome profiling data to decode mRNA translation at codon resolution. Nucleic Acids Research. PMID 32427338 DOI: 10.1093/Nar/Gkaa395 |
0.311 |
|
| 2020 |
Chen H, Gu L, Orellana EA, Wang Y, Guo J, Liu Q, Wang L, Shen Z, Wu H, Gregory RI, Xing Y, Shi Y. METTL4 is an snRNA mAm methyltransferase that regulates RNA splicing. Cell Research. PMID 31913360 DOI: 10.1038/S41422-019-0270-4 |
0.364 |
|
| 2019 |
Lin S, Liu Q, Jiang YZ, Gregory RI. Nucleotide resolution profiling of mG tRNA modification by TRAC-Seq. Nature Protocols. PMID 31619810 DOI: 10.1038/S41596-019-0226-7 |
0.335 |
|
| 2019 |
Pirouz M, Munafò M, Ebrahimi AG, Choe J, Gregory RI. Exonuclease requirements for mammalian ribosomal RNA biogenesis and surveillance. Nature Structural & Molecular Biology. PMID 31160785 DOI: 10.1038/S41594-019-0234-X |
0.374 |
|
| 2019 |
Liu Q, Gregory RI. RNAmod: an integrated system for the annotation of mRNA modifications. Nucleic Acids Research. PMID 31147718 DOI: 10.1093/Nar/Gkz479 |
0.382 |
|
| 2019 |
Paris J, Morgan M, Campos J, Spencer GJ, Shmakova A, Ivanova I, Mapperley C, Lawson H, Wotherspoon DA, Sepulveda C, Vukovic M, Allen L, Sarapuu A, Tavosanis A, Guitart AV, ... ... Gregory RI, et al. Targeting the RNA mA Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. PMID 31031138 DOI: 10.1016/J.Stem.2019.03.021 |
0.407 |
|
| 2018 |
Pirouz M, Ebrahimi AG, Gregory RI. Unraveling 3'-end RNA uridylation at nucleotide resolution. Methods (San Diego, Calif.). PMID 30395968 DOI: 10.1016/J.Ymeth.2018.10.024 |
0.4 |
|
| 2018 |
Choe J, Lin S, Zhang W, Liu Q, Wang L, Ramirez-Moya J, Du P, Kim W, Tang S, Sliz P, Santisteban P, George RE, Richards WG, Wong KK, Locker N, ... ... Gregory RI, et al. mRNA circularization by METTL3-eIF3h enhances translation and promotes oncogenesis. Nature. PMID 30232453 DOI: 10.1038/S41586-018-0538-8 |
0.388 |
|
| 2018 |
Park HH, Triboulet R, Bentler M, Guda S, Du P, Xu H, Gregory RI, Brendel C, Williams DA. DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAs. Molecular Therapy. Nucleic Acids. 12: 591-599. PMID 30195795 DOI: 10.1016/J.Omtn.2018.07.002 |
0.424 |
|
| 2018 |
Lin S, Liu Q, Lelyveld VS, Choe J, Szostak JW, Gregory RI. Mettl1/Wdr4-Mediated mG tRNA Methylome Is Required for Normal mRNA Translation and Embryonic Stem Cell Self-Renewal and Differentiation. Molecular Cell. PMID 29983320 DOI: 10.1016/J.Molcel.2018.06.001 |
0.364 |
|
| 2018 |
Du P, Pirouz M, Choi J, Huebner AJ, Clement K, Meissner A, Hochedlinger K, Gregory RI. An Intermediate Pluripotent State Controlled by MicroRNAs Is Required for the Naive-to-Primed Stem Cell Transition. Cell Stem Cell. PMID 29804889 DOI: 10.1016/J.Stem.2018.04.021 |
0.474 |
|
| 2018 |
Ogórek B, Lam HC, Khabibullin D, Liu HJ, Nijmeh J, Triboulet R, Kwiatkowski DJ, Gregory RI, Henske EP. TSC2 Regulates microRNA Biogenesis via mTORC1 and GSK3β. Human Molecular Genetics. PMID 29509898 DOI: 10.1093/Hmg/Ddy073 |
0.423 |
|
| 2017 |
Cinkornpumin J, Roos M, Nguyen L, Liu X, Gaeta X, Lin S, Chan DN, Liu A, Gregory RI, Jung M, Chute J, Zhu H, Lowry WE. A small molecule screen to identify regulators of let-7 targets. Scientific Reports. 7: 15973. PMID 29162914 DOI: 10.1038/S41598-017-16258-9 |
0.429 |
|
| 2016 |
Tsanov KM, Pearson DS, Wu Z, Han A, Triboulet R, Seligson MT, Powers JT, Osborne JK, Kane S, Gygi SP, Gregory RI, Daley GQ. LIN28 phosphorylation by MAPK/ERK couples signalling to the post-transcriptional control of pluripotency. Nature Cell Biology. PMID 27992407 DOI: 10.1038/Ncb3453 |
0.444 |
|
| 2016 |
Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim YJ, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype. The Journal of Clinical Investigation. 126: 3868-3878. PMID 27599293 DOI: 10.1172/Jci87885 |
0.409 |
|
| 2016 |
Pirouz M, Du P, Munafò M, Gregory RI. Dis3l2-Mediated Decay Is a Quality Control Pathway for Noncoding RNAs. Cell Reports. PMID 27498873 DOI: 10.1016/J.Celrep.2016.07.025 |
0.418 |
|
| 2016 |
Lin S, Choe J, Du P, Triboulet R, Gregory RI. The m(6)A Methyltransferase METTL3 Promotes Translation in Human Cancer Cells. Molecular Cell. PMID 27117702 DOI: 10.1016/J.Molcel.2016.03.021 |
0.367 |
|
| 2016 |
Brendel C, Guda S, Renella R, Bauer DE, Canver MC, Kim Y, Heeney MM, Klatt D, Fogel J, Milsom MD, Orkin SH, Gregory RI, Williams DA. 282. Circumventing Hematopoietic Toxicities and Reversing Sickle Phenotype by Lineage-Specific BCL11A Knock Down and γ-Globin Induction Molecular Therapy. 24: S113. DOI: 10.1016/S1525-0016(16)33091-X |
0.413 |
|
| 2015 |
Triboulet R, Pirouz M, Gregory RI. A Single Let-7 MicroRNA Bypasses LIN28-Mediated Repression. Cell Reports. 13: 260-6. PMID 26440890 DOI: 10.1016/J.Celrep.2015.08.086 |
0.541 |
|
| 2015 |
Das PP, Hendrix DA, Apostolou E, Buchner AH, Canver MC, Beyaz S, Ljuboja D, Kuintzle R, Kim W, Karnik R, Shao Z, Xie H, Xu J, De Los Angeles A, Zhang Y, ... ... Gregory RI, et al. PRC2 Is Required to Maintain Expression of the Maternal Gtl2-Rian-Mirg Locus by Preventing De Novo DNA Methylation in Mouse Embryonic Stem Cells. Cell Reports. 12: 1456-1470. PMID 26299972 DOI: 10.1016/J.Celrep.2015.07.053 |
0.439 |
|
| 2015 |
Du P, Wang L, Sliz P, Gregory RI. A Biogenesis Step Upstream of Microprocessor Controls miR-17∼92 Expression. Cell. 162: 885-99. PMID 26255770 DOI: 10.1016/J.Cell.2015.07.008 |
0.426 |
|
| 2015 |
Lin S, Gregory RI. Identification of small molecule inhibitors of Zcchc11 TUTase activity. Rna Biology. 12: 792-800. PMID 26114892 DOI: 10.1080/15476286.2015.1058478 |
0.468 |
|
| 2015 |
Guda S, Brendel C, Renella R, Du P, Bauer DE, Canver MC, Grenier JK, Grimson AW, Kamran SC, Thornton J, de Boer H, Root DE, Milsom MD, Orkin SH, Gregory RI, et al. miRNA-embedded shRNAs for Lineage-specific BCL11A Knockdown and Hemoglobin F Induction. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 1465-74. PMID 26080908 DOI: 10.1038/Mt.2015.113 |
0.487 |
|
| 2015 |
Lin S, Gregory RI. MicroRNA biogenesis pathways in cancer. Nature Reviews. Cancer. 15: 321-33. PMID 25998712 DOI: 10.1038/Nrc3932 |
0.425 |
|
| 2014 |
Thornton JE, Du P, Jing L, Sjekloca L, Lin S, Grossi E, Sliz P, Zon LI, Gregory RI. Selective microRNA uridylation by Zcchc6 (TUT7) and Zcchc11 (TUT4). Nucleic Acids Research. 42: 11777-91. PMID 25223788 DOI: 10.1093/Nar/Gku805 |
0.49 |
|
| 2014 |
Mori M, Triboulet R, Mohseni M, Schlegelmilch K, Shrestha K, Camargo FD, Gregory RI. Hippo signaling regulates microprocessor and links cell-density-dependent miRNA biogenesis to cancer. Cell. 156: 893-906. PMID 24581491 DOI: 10.1016/J.Cell.2013.12.043 |
0.489 |
|
| 2014 |
Lin S, Gregory RI. Methyltransferases modulate RNA stability in embryonic stem cells. Nature Cell Biology. 16: 129-31. PMID 24481042 DOI: 10.1038/Ncb2914 |
0.404 |
|
| 2014 |
Brendel C, Guda S, Renella R, Du P, Bauer DE, Canver MC, Kamran SC, Thornton J, de Boer H, Milsom MD, Orkin SH, Gregory R, Williams DA. Optimization of Bcl11a Knockdown By miRNA Scaffold Embedded Shrnas Leading to Enhanced Induction of Fetal Hemoglobin in Erythroid Cells for the Treatment of Beta-Hemoglobinopathies Blood. 124: 2150-2150. DOI: 10.1182/Blood.V124.21.2150.2150 |
0.455 |
|
| 2013 |
Kallen AN, Zhou XB, Xu J, Qiao C, Ma J, Yan L, Lu L, Liu C, Yi JS, Zhang H, Min W, Bennett AM, Gregory RI, Ding Y, Huang Y. The imprinted H19 lncRNA antagonizes let-7 microRNAs. Molecular Cell. 52: 101-12. PMID 24055342 DOI: 10.1016/J.Molcel.2013.08.027 |
0.371 |
|
| 2013 |
Martinez NJ, Chang HM, Borrajo Jde R, Gregory RI. The co-chaperones Fkbp4/5 control Argonaute2 expression and facilitate RISC assembly. Rna (New York, N.Y.). 19: 1583-93. PMID 24049110 DOI: 10.1261/Rna.040790.113 |
0.539 |
|
| 2013 |
Chang HM, Triboulet R, Thornton JE, Gregory RI. A role for the Perlman syndrome exonuclease Dis3l2 in the Lin28-let-7 pathway. Nature. 497: 244-8. PMID 23594738 DOI: 10.1038/nature12119 |
0.391 |
|
| 2013 |
Martinez NJ, Gregory RI. Argonaute2 expression is post-transcriptionally coupled to microRNA abundance. Rna (New York, N.Y.). 19: 605-12. PMID 23485552 DOI: 10.1261/Rna.036434.112 |
0.542 |
|
| 2013 |
Shinoda G, De Soysa TY, Seligson MT, Yabuuchi A, Fujiwara Y, Huang PY, Hagan JP, Gregory RI, Moss EG, Daley GQ. Lin28a regulates germ cell pool size and fertility. Stem Cells (Dayton, Ohio). 31: 1001-9. PMID 23378032 DOI: 10.1002/Stem.1343 |
0.353 |
|
| 2012 |
Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, et al. EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent. Science (New York, N.Y.). 338: 1465-9. PMID 23239736 DOI: 10.1126/Science.1227604 |
0.343 |
|
| 2012 |
Silveira-Neto AP, Leal LF, Emerman AB, Henderson KD, Piskounova E, Henderson BE, Gregory RI, Silveira LF, Hirschhorn JN, Nguyen TT, Beneduzzi D, Tusset C, Reis AC, Brito VN, Mendonca BB, et al. Absence of functional LIN28B mutations in a large cohort of patients with idiopathic central precocious puberty. Hormone Research in Pã¦Diatrics. 78: 144-50. PMID 22964795 DOI: 10.1159/000342212 |
0.678 |
|
| 2012 |
Thornton JE, Chang HM, Piskounova E, Gregory RI. Lin28-mediated control of let-7 microRNA expression by alternative TUTases Zcchc11 (TUT4) and Zcchc6 (TUT7). Rna (New York, N.Y.). 18: 1875-85. PMID 22898984 DOI: 10.1261/Rna.034538.112 |
0.724 |
|
| 2012 |
Thornton JE, Gregory RI. How does Lin28 let-7 control development and disease? Trends in Cell Biology. 22: 474-82. PMID 22784697 DOI: 10.1016/J.Tcb.2012.06.001 |
0.499 |
|
| 2012 |
Chang HM, Martinez NJ, Thornton JE, Hagan JP, Nguyen KD, Gregory RI. Trim71 cooperates with microRNAs to repress Cdkn1a expression and promote embryonic stem cell proliferation. Nature Communications. 3: 923. PMID 22735451 DOI: 10.1038/Ncomms1909 |
0.44 |
|
| 2011 |
Piskounova E, Polytarchou C, Thornton JE, LaPierre RJ, Pothoulakis C, Hagan JP, Iliopoulos D, Gregory RI. Lin28A and Lin28B inhibit let-7 microRNA biogenesis by distinct mechanisms. Cell. 147: 1066-79. PMID 22118463 DOI: 10.1016/J.Cell.2011.10.039 |
0.69 |
|
| 2011 |
Nam Y, Chen C, Gregory RI, Chou JJ, Sliz P. Molecular basis for interaction of let-7 microRNAs with Lin28. Cell. 147: 1080-91. PMID 22078496 DOI: 10.1016/J.Cell.2011.10.020 |
0.517 |
|
| 2011 |
Zhu H, Shyh-Chang N, Segrè AV, Shinoda G, Shah SP, Einhorn WS, Takeuchi A, Engreitz JM, Hagan JP, Kharas MG, Urbach A, Thornton JE, Triboulet R, Gregory RI, et al. The Lin28/let-7 axis regulates glucose metabolism. Cell. 147: 81-94. PMID 21962509 DOI: 10.1016/J.Cell.2011.08.033 |
0.305 |
|
| 2011 |
Triboulet R, Gregory RI. Autoregulatory mechanisms controlling the microprocessor. Advances in Experimental Medicine and Biology. 700: 56-66. PMID 21755473 DOI: 10.1007/978-1-4419-7823-3_6 |
0.513 |
|
| 2011 |
Chang HM, Gregory RI. MicroRNAs and reprogramming. Nature Biotechnology. 29: 499-500. PMID 21654668 DOI: 10.1038/Nbt.1889 |
0.392 |
|
| 2011 |
Basu U, Meng FL, Keim C, Grinstein V, Pefanis E, Eccleston J, Zhang T, Myers D, Wasserman CR, Wesemann DR, Januszyk K, Gregory RI, Deng H, Lima CD, Alt FW. The RNA exosome targets the AID cytidine deaminase to both strands of transcribed duplex DNA substrates. Cell. 144: 353-63. PMID 21255825 DOI: 10.1016/J.Cell.2011.01.001 |
0.353 |
|
| 2011 |
Suk K, Choi J, Suzuki Y, Ozturk SB, Mellor JC, Wong KH, MacKay JL, Gregory RI, Roth FP. Reconstitution of human RNA interference in budding yeast. Nucleic Acids Research. 39: e43. PMID 21252293 DOI: 10.1093/Nar/Gkq1321 |
0.37 |
|
| 2010 |
Triboulet R, Gregory RI. Autoregulatory mechanisms controlling the Microprocessor. Advances in Experimental Medicine and Biology. 700: 56-66. PMID 21627030 |
0.425 |
|
| 2010 |
Triboulet R, Gregory RI. Pumilio turns on microRNA function. Nature Cell Biology. 12: 928-9. PMID 20885420 DOI: 10.1038/Ncb1010-928 |
0.456 |
|
| 2010 |
Martinez NJ, Gregory RI. MicroRNA gene regulatory pathways in the establishment and maintenance of ESC identity. Cell Stem Cell. 7: 31-5. PMID 20621047 DOI: 10.1016/J.Stem.2010.06.011 |
0.448 |
|
| 2009 |
Hagan JP, Piskounova E, Gregory RI. Lin28 recruits the TUTase Zcchc11 to inhibit let-7 maturation in mouse embryonic stem cells. Nature Structural & Molecular Biology. 16: 1021-5. PMID 19713958 DOI: 10.1038/Nsmb.1676 |
0.753 |
|
| 2009 |
Triboulet R, Chang HM, Lapierre RJ, Gregory RI. Post-transcriptional control of DGCR8 expression by the Microprocessor. Rna (New York, N.Y.). 15: 1005-11. PMID 19383765 DOI: 10.1261/Rna.1591709 |
0.519 |
|
| 2009 |
Winter J, Jung S, Keller S, Gregory RI, Diederichs S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nature Cell Biology. 11: 228-34. PMID 19255566 DOI: 10.1038/Ncb0309-228 |
0.482 |
|
| 2009 |
Gregory RI, Khosla S, Feil R. Probing chromatin structure with nuclease sensitivity assays. Methods in Molecular Biology (Clifton, N.J.). 181: 269-84. PMID 12843457 DOI: 10.1385/1-59259-211-2:269 |
0.311 |
|
| 2008 |
Ho J, Ng KH, Rosen S, Dostal A, Gregory RI, Kreidberg JA. Podocyte-specific loss of functional microRNAs leads to rapid glomerular and tubular injury. Journal of the American Society of Nephrology : Jasn. 19: 2069-75. PMID 18832437 DOI: 10.1681/Asn.2008020162 |
0.477 |
|
| 2008 |
Piskounova E, Viswanathan SR, Janas M, LaPierre RJ, Daley GQ, Sliz P, Gregory RI. Determinants of microRNA processing inhibition by the developmentally regulated RNA-binding protein Lin28. The Journal of Biological Chemistry. 283: 21310-4. PMID 18550544 DOI: 10.1074/Jbc.C800108200 |
0.739 |
|
| 2008 |
Faber J, Gregory RI, Armstrong SA. Linking miRNA regulation to BCR-ABL expression: the next dimension. Cancer Cell. 13: 467-9. PMID 18538729 DOI: 10.1016/J.Ccr.2008.05.013 |
0.4 |
|
| 2008 |
Li Q, Gregory RI. MicroRNA regulation of stem cell fate. Cell Stem Cell. 2: 195-6. PMID 18371442 DOI: 10.1016/J.Stem.2008.02.008 |
0.396 |
|
| 2008 |
Viswanathan SR, Daley GQ, Gregory RI. Selective blockade of microRNA processing by Lin28. Science (New York, N.Y.). 320: 97-100. PMID 18292307 DOI: 10.1126/Science.1154040 |
0.509 |
|
| 2007 |
Chendrimada TP, Finn KJ, Ji X, Baillat D, Gregory RI, Liebhaber SA, Pasquinelli AE, Shiekhattar R. MicroRNA silencing through RISC recruitment of eIF6. Nature. 447: 823-8. PMID 17507929 DOI: 10.1038/Nature05841 |
0.512 |
|
| 2006 |
Gregory RI, Chendrimada TP, Shiekhattar R. MicroRNA biogenesis: isolation and characterization of the microprocessor complex. Methods in Molecular Biology (Clifton, N.J.). 342: 33-47. PMID 16957365 DOI: 10.1385/1-59745-123-1:33 |
0.492 |
|
| 2005 |
Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 123: 631-40. PMID 16271387 DOI: 10.1016/J.Cell.2005.10.022 |
0.474 |
|
| 2005 |
Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, Nishikura K, Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature. 436: 740-4. PMID 15973356 DOI: 10.1038/Nature03868 |
0.505 |
|
| 2005 |
Gregory RI, Shiekhattar R. MicroRNA biogenesis and cancer. Cancer Research. 65: 3509-12. PMID 15867338 DOI: 10.1158/0008-5472.Can-05-0298 |
0.514 |
|
| 2004 |
Gregory RI, Shiekhattar R. Chromatin modifiers and carcinogenesis. Trends in Cell Biology. 14: 695-702. PMID 15564046 DOI: 10.1016/J.Tcb.2004.10.002 |
0.319 |
|
| 2004 |
Gregory RI, Yan KP, Amuthan G, Chendrimada T, Doratotaj B, Cooch N, Shiekhattar R. The Microprocessor complex mediates the genesis of microRNAs. Nature. 432: 235-40. PMID 15531877 DOI: 10.1038/Nature03120 |
0.519 |
|
| 2002 |
Gregory RI, O'Neill LP, Randall TE, Fournier C, Khosla S, Turner BM, Feil R. Inhibition of histone deacetylases alters allelic chromatin conformation at the imprinted U2af1-rs1 locus in mouse embryonic stem cells. The Journal of Biological Chemistry. 277: 11728-34. PMID 11821379 DOI: 10.1074/Jbc.M105775200 |
0.325 |
|
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