Streamson Chua - Publications

Columbia University, New York, NY 
Animal Physiology Biology, Neuroscience Biology, Nutrition

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Jeong JH, Woo YJ, Chua S, Jo YH. Single-Cell Gene Expression Analysis of Cholinergic Neurons in the Arcuate Nucleus of the Hypothalamus. Plos One. 11: e0162839. PMID 27611685 DOI: 10.1371/Journal.Pone.0162839  0.36
2015 Sachdev S, Wang Q, Billington C, Connett J, Ahmed L, Inabnet W, Chua S, Ikramuddin S, Korner J. FGF 19 and Bile Acids Increase Following Roux-en-Y Gastric Bypass but Not After Medical Management in Patients with Type 2 Diabetes. Obesity Surgery. PMID 26259981 DOI: 10.1007/S11695-015-1834-0  0.36
2015 Jeong JH, Lee DK, Blouet C, Ruiz HH, Buettner C, Chua S, Schwartz GJ, Jo YH. Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism. Molecular Metabolism. 4: 483-92. PMID 26042202 DOI: 10.1016/J.Molmet.2015.03.006  0.36
2015 Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, et al. Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes & Development. 29: 934-47. PMID 25934505 DOI: 10.1101/Gad.258350.115  0.36
2015 Lee DK, Jeong JH, Chun SK, Chua S, Jo YH. Interplay between glucose and leptin signalling determines the strength of GABAergic synapses at POMC neurons. Nature Communications. 6: 6618. PMID 25808323 DOI: 10.1038/Ncomms7618  0.36
2014 Meek TH, Matsen ME, Damian V, Cubelo A, Chua SC, Morton GJ. Role of melanocortin signaling in neuroendocrine and metabolic actions of leptin in male rats with uncontrolled diabetes. Endocrinology. 155: 4157-67. PMID 25137027 DOI: 10.1210/En.2014-1169  0.36
2014 Marcelin G, Jo YH, Li X, Schwartz GJ, Zhang Y, Dun NJ, Lyu RM, Blouet C, Chang JK, Chua S. Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism. Molecular Metabolism. 3: 19-28. PMID 24567901 DOI: 10.1016/J.Molmet.2013.10.002  0.36
2013 Sheffer-Babila S, Sun Y, Israel DD, Liu SM, Neal-Perry G, Chua SC. Agouti-related peptide plays a critical role in leptin's effects on female puberty and reproduction. American Journal of Physiology. Endocrinology and Metabolism. 305: E1512-20. PMID 24169048 DOI: 10.1152/ajpendo.00241.2013  0.36
2013 Marcelin G, Liu SM, Schwartz GJ, Chua SC. Identification of a loss-of-function mutation in Ube2l6 associated with obesity resistance. Diabetes. 62: 2784-95. PMID 23557705 DOI: 10.2337/db12-1054  0.36
2013 Lu Z, Marcelin G, Bauzon F, Wang H, Fu H, Dun SL, Zhao H, Li X, Jo YH, Wardlaw S, Dun N, Chua S, Zhu L. pRb is an obesity suppressor in hypothalamus and high-fat diet inhibits pRb in this location. The Embo Journal. 32: 844-57. PMID 23403926 DOI: 10.1038/Emboj.2013.25  0.36
2013 McKimpson WM, Weinberger J, Czerski L, Zheng M, Crow MT, Pessin JE, Chua SC, Kitsis RN. The apoptosis inhibitor ARC alleviates the ER stress response to promote β-cell survival. Diabetes. 62: 183-93. PMID 22933109 DOI: 10.2337/Db12-0504  0.36
2012 Marino JS, Iler J, Dowling AR, Chua S, Bruning JC, Coppari R, Hill JW. Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation. Plos One. 7: e48643. PMID 23119079 DOI: 10.1371/Journal.Pone.0048643  0.36
2012 Blouet C, Liu SM, Jo YH, Chua S, Schwartz GJ. TXNIP in Agrp neurons regulates adiposity, energy expenditure, and central leptin sensitivity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9870-7. PMID 22815502 DOI: 10.1523/Jneurosci.0353-12.2012  0.36
2012 Dutia R, Kim AJ, Mosharov E, Savontaus E, Chua SC, Wardlaw SL. Regulation of prolactin in mice with altered hypothalamic melanocortin activity. Peptides. 37: 6-12. PMID 22800691 DOI: 10.1016/J.Peptides.2012.07.006  0.36
2012 Guo M, Lu Y, Garza JC, Li Y, Chua SC, Zhang W, Lu B, Lu XY. Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression. Translational Psychiatry. 2: e83. PMID 22408745 DOI: 10.1038/Tp.2012.9  0.36
2012 Israel DD, Sheffer-Babila S, de Luca C, Jo YH, Liu SM, Xia Q, Spergel DJ, Dun SL, Dun NJ, Chua SC. Effects of leptin and melanocortin signaling interactions on pubertal development and reproduction. Endocrinology. 153: 2408-19. PMID 22408174 DOI: 10.1210/En.2011-1822  0.36
2012 Marcelin G, Liu SM, Li X, Schwartz GJ, Chua S. Genetic control of ATGL-mediated lipolysis modulates adipose triglyceride stores in leptin-deficient mice. Journal of Lipid Research. 53: 964-72. PMID 22383686 DOI: 10.1194/Jlr.M022467  0.36
2012 Pan W, Hsuchou H, Cornelissen-Guillaume GG, Jayaram B, Wang Y, Tu H, Halberg F, Wu X, Chua SC, Kastin AJ. Endothelial leptin receptor mutation provides partial resistance to diet-induced obesity. Journal of Applied Physiology (Bethesda, Md. : 1985). 112: 1410-8. PMID 22323652 DOI: 10.1152/japplphysiol.00590.2011  0.36
2012 Nagajyothi F, Desruisseaux MS, Machado FS, Upadhya R, Zhao D, Schwartz GJ, Teixeira MM, Albanese C, Lisanti MP, Chua SC, Weiss LM, Scherer PE, Tanowitz HB. Response of adipose tissue to early infection with Trypanosoma cruzi (Brazil strain). The Journal of Infectious Diseases. 205: 830-40. PMID 22293433 DOI: 10.1093/Infdis/Jir840  0.36
2011 Tanowitz HB, Jelicks LA, Machado FS, Esper L, Qi X, Desruisseaux MS, Chua SC, Scherer PE, Nagajyothi F. Adipose tissue, diabetes and Chagas disease. Advances in Parasitology. 76: 235-50. PMID 21884894 DOI: 10.1016/B978-0-12-385895-5.00010-4  0.36
2011 Vong L, Ye C, Yang Z, Choi B, Chua S, Lowell BB. Leptin action on GABAergic neurons prevents obesity and reduces inhibitory tone to POMC neurons. Neuron. 71: 142-54. PMID 21745644 DOI: 10.1016/J.Neuron.2011.05.028  0.36
2011 Hsuchou H, Kastin AJ, Tu H, Markadakis EN, Stone KP, Wang Y, Heymsfield SB, Chua SS, Obici S, Magrisso IJ, Pan W. Effects of cell-type specific leptin receptor mutation on leptin transport across the BBB. Peptides. 32: 1392-9. PMID 21616110 DOI: 10.1016/J.Peptides.2011.05.011  0.36
2011 Duggal P, Guo X, Haque R, Peterson KM, Ricklefs S, Mondal D, Alam F, Noor Z, Verkerke HP, Marie C, Leduc CA, Chua SC, Myers MG, Leibel RL, Houpt E, et al. A mutation in the leptin receptor is associated with Entamoeba histolytica infection in children. The Journal of Clinical Investigation. 121: 1191-8. PMID 21393862 DOI: 10.1172/Jci45294  0.36
2011 Luo N, Marcelin G, Liu SM, Schwartz G, Chua S. Neuropeptide Y and agouti-related peptide mediate complementary functions of hyperphagia and reduced energy expenditure in leptin receptor deficiency. Endocrinology. 152: 883-9. PMID 21285324 DOI: 10.1210/En.2010-1135  0.36
2011 Donato J, Cravo RM, Frazão R, Gautron L, Scott MM, Lachey J, Castro IA, Margatho LO, Lee S, Lee C, Richardson JA, Friedman J, Chua S, Coppari R, Zigman JM, et al. Leptin's effect on puberty in mice is relayed by the ventral premammillary nucleus and does not require signaling in Kiss1 neurons. The Journal of Clinical Investigation. 121: 355-68. PMID 21183787 DOI: 10.1172/Jci45106  0.36
2011 Guo X, Roberts MR, Becker SM, Podd B, Zhang Y, Chua SC, Myers MG, Duggal P, Houpt ER, Petri WA. Leptin signaling in intestinal epithelium mediates resistance to enteric infection by Entamoeba histolytica. Mucosal Immunology. 4: 294-303. PMID 21124310 DOI: 10.1038/Mi.2010.76  0.36
2010 Huynh FK, Levi J, Denroche HC, Gray SL, Voshol PJ, Neumann UH, Speck M, Chua SC, Covey SD, Kieffer TJ. Disruption of hepatic leptin signaling protects mice from age- and diet-related glucose intolerance. Diabetes. 59: 3032-40. PMID 20876720 DOI: 10.2337/Db10-0074  0.36
2010 Marcelin G, Chua S. Contributions of adipocyte lipid metabolism to body fat content and implications for the treatment of obesity. Current Opinion in Pharmacology. 10: 588-93. PMID 20860920 DOI: 10.1016/j.coph.2010.05.008  0.36
2010 Nagajyothi F, Zhao D, Machado FS, Weiss LM, Schwartz GJ, Desruisseaux MS, Zhao Y, Factor SM, Huang H, Albanese C, Teixeira MM, Scherer PE, Chua SC, Tanowitz HB. Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. The Journal of Infectious Diseases. 202: 1104-13. PMID 20726767 DOI: 10.1086/656189  0.36
2010 Hill JW, Elias CF, Fukuda M, Williams KW, Berglund ED, Holland WL, Cho YR, Chuang JC, Xu Y, Choi M, Lauzon D, Lee CE, Coppari R, Richardson JA, Zigman JM, ... Chua S, et al. Direct insulin and leptin action on pro-opiomelanocortin neurons is required for normal glucose homeostasis and fertility. Cell Metabolism. 11: 286-97. PMID 20374961 DOI: 10.1016/J.Cmet.2010.03.002  0.36
2010 Iqbal J, Li X, Chang BH, Chan L, Schwartz GJ, Chua SC, Hussain MM. An intrinsic gut leptin-melanocortin pathway modulates intestinal microsomal triglyceride transfer protein and lipid absorption. Journal of Lipid Research. 51: 1929-42. PMID 20164094 DOI: 10.1194/jlr.M005744  0.36
2010 Iskandar K, Cao Y, Hayashi Y, Nakata M, Takano E, Yada T, Zhang C, Ogawa W, Oki M, Chua S, Itoh H, Noda T, Kasuga M, Nakae J. PDK-1/FoxO1 pathway in POMC neurons regulates Pomc expression and food intake. American Journal of Physiology. Endocrinology and Metabolism. 298: E787-98. PMID 20103739 DOI: 10.1152/Ajpendo.00512.2009  0.36
2010 Israel D, Chua S. Leptin receptor modulation of adiposity and fertility. Trends in Endocrinology and Metabolism: Tem. 21: 10-6. PMID 19854659 DOI: 10.1016/J.Tem.2009.07.004  0.36
2009 Khan T, Hamilton MP, Mundy DI, Chua SC, Scherer PE. Impact of simvastatin on adipose tissue: pleiotropic effects in vivo. Endocrinology. 150: 5262-72. PMID 19819942 DOI: 10.1210/En.2009-0603  0.36
2009 Nagajyothi F, Desruisseaux MS, Weiss LM, Chua S, Albanese C, Machado FS, Esper L, Lisanti MP, Teixeira MM, Scherer PE, Tanowitz HB. Chagas disease, adipose tissue and the metabolic syndrome. MemóRias Do Instituto Oswaldo Cruz. 104: 219-25. PMID 19753477 DOI: 10.1590/S0074-02762009000900028  0.36
2009 Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG, Chua SC, Wang Q, Kim JK, Kaestner KH, Karsenty G. An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion. Annals of the New York Academy of Sciences. 1173: E20-30. PMID 19751411 DOI: 10.1111/J.1749-6632.2009.05061.X  0.36
2009 Leinninger GM, Jo YH, Leshan RL, Louis GW, Yang H, Barrera JG, Wilson H, Opland DM, Faouzi MA, Gong Y, Jones JC, Rhodes CJ, Chua S, Diano S, Horvath TL, et al. Leptin acts via leptin receptor-expressing lateral hypothalamic neurons to modulate the mesolimbic dopamine system and suppress feeding. Cell Metabolism. 10: 89-98. PMID 19656487 DOI: 10.1016/J.Cmet.2009.06.011  0.36
2008 Kim KW, Jo YH, Zhao L, Stallings NR, Chua SC, Parker KL. Steroidogenic factor 1 regulates expression of the cannabinoid receptor 1 in the ventromedial hypothalamic nucleus. Molecular Endocrinology (Baltimore, Md.). 22: 1950-61. PMID 18511494 DOI: 10.1210/me.2008-0127  0.36
2008 van de Wall E, Leshan R, Xu AW, Balthasar N, Coppari R, Liu SM, Jo YH, MacKenzie RG, Allison DB, Dun NJ, Elmquist J, Lowell BB, Barsh GS, de Luca C, Myers MG, ... ... Chua SC, et al. Collective and individual functions of leptin receptor modulated neurons controlling metabolism and ingestion. Endocrinology. 149: 1773-85. PMID 18162515 DOI: 10.1210/En.2007-1132  0.36
2007 Hsing AW, Sakoda LC, Chua S. Obesity, metabolic syndrome, and prostate cancer. The American Journal of Clinical Nutrition. 86: s843-57. PMID 18265478 DOI: 10.1093/Ajcn/86.3.843S  0.36
2006 Zheng Z, Pavlidis P, Chua S, D'Agati VD, Gharavi AG. An ancestral haplotype defines susceptibility to doxorubicin nephropathy in the laboratory mouse. Journal of the American Society of Nephrology : Jasn. 17: 1796-800. PMID 16775033 DOI: 10.1681/Asn.2005121373  0.36
2006 Collins SJ, Alexander SL, Lopez-Guisa JM, Cai X, Maruvada R, Chua SC, Zhang G, Okamura DM, Matsuo S, Eddy AA. Plasminogen activator inhibitor-1 deficiency has renal benefits but some adverse systemic consequences in diabetic mice. Nephron. Experimental Nephrology. 104: e23-34. PMID 16735799 DOI: 10.1159/000093673  0.36
2006 Kitamura T, Feng Y, Kitamura YI, Chua SC, Xu AW, Barsh GS, Rossetti L, Accili D. Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake. Nature Medicine. 12: 534-40. PMID 16604086 DOI: 10.1038/Nm1392  0.36
2006 Luo N, Liu SM, Liu H, Li Q, Xu Q, Sun X, Davis B, Li J, Chua S. Allelic variation on chromosome 5 controls beta-cell mass expansion during hyperglycemia in leptin receptor-deficient diabetes mice. Endocrinology. 147: 2287-95. PMID 16484328 DOI: 10.1210/En.2005-0853  0.36
2006 Dhillon H, Zigman JM, Ye C, Lee CE, McGovern RA, Tang V, Kenny CD, Christiansen LM, White RD, Edelstein EA, Coppari R, Balthasar N, Cowley MA, Chua S, Elmquist JK, et al. Leptin directly activates SF1 neurons in the VMH, and this action by leptin is required for normal body-weight homeostasis. Neuron. 49: 191-203. PMID 16423694 DOI: 10.1016/J.Neuron.2005.12.021  0.36
2005 de Luca C, Kowalski TJ, Zhang Y, Elmquist JK, Lee C, Kilimann MW, Ludwig T, Liu SM, Chua SC. Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes. The Journal of Clinical Investigation. 115: 3484-93. PMID 16284652 DOI: 10.1172/Jci24059  0.36
2005 Coppari R, Ichinose M, Lee CE, Pullen AE, Kenny CD, McGovern RA, Tang V, Liu SM, Ludwig T, Chua SC, Lowell BB, Elmquist JK. The hypothalamic arcuate nucleus: a key site for mediating leptin's effects on glucose homeostasis and locomotor activity. Cell Metabolism. 1: 63-72. PMID 16054045 DOI: 10.1016/J.Cmet.2004.12.004  0.36
2005 Wang Z, Jiang T, Li J, Proctor G, McManaman JL, Lucia S, Chua S, Levi M. Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes. Diabetes. 54: 2328-35. PMID 16046298 DOI: 10.2337/Diabetes.54.8.2328  0.36
2005 Levin BE, Magnan C, Migrenne S, Chua SC, Dunn-Meynell AA. F-DIO obesity-prone rat is insulin resistant before obesity onset. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 289: R704-11. PMID 15879056 DOI: 10.1152/Ajpregu.00216.2005  0.36
2005 Zheng Z, Schmidt-Ott KM, Chua S, Foster KA, Frankel RZ, Pavlidis P, Barasch J, D'Agati VD, Gharavi AG. A Mendelian locus on chromosome 16 determines susceptibility to doxorubicin nephropathy in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 102: 2502-7. PMID 15699352 DOI: 10.1073/Pnas.0409786102  0.36
2004 Balthasar N, Coppari R, McMinn J, Liu SM, Lee CE, Tang V, Kenny CD, McGovern RA, Chua SC, Elmquist JK, Lowell BB. Leptin receptor signaling in POMC neurons is required for normal body weight homeostasis. Neuron. 42: 983-91. PMID 15207242 DOI: 10.1016/j.neuron.2004.06.004  0.36
2004 Moran TH, Langhans W, Chua S, Geary N. A special issue of reviews on ingestive science Physiology and Behavior. 81: 175-177. DOI: 10.1016/J.Physbeh.2004.02.003  0.36
2003 Levin BE, Dunn-Meynell AA, McMinn JE, Alperovich M, Cunningham-Bussel A, Chua SC. A new obesity-prone, glucose-intolerant rat strain (F.DIO). American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 285: R1184-91. PMID 12855420 DOI: 10.1152/Ajpregu.00267.2003  0.36
2003 Ho GYF, Melman A, Liu SM, Li M, Yu H, Negassa A, Burk RD, Hsing AW, Ghavamian R, Chua SC. Polymorphism of the insulin gene is associated with increased prostate cancer risk British Journal of Cancer. 88: 263-269. PMID 12610512 DOI: 10.1038/Sj.Bjc.6600747  0.36
2003 Hsing AW, Gao YT, Chua S, Deng J, Stanczyk FZ. Insulin resistance and prostate cancer risk. Journal of the National Cancer Institute. 95: 67-71. PMID 12509402 DOI: 10.1093/Jnci/95.1.67  0.36
2001 Hsing AW, Chua S, Gao YT, Gentzschein E, Chang L, Deng J, Stanczyk FZ. Prostate cancer risk and serum levels of insulin and leptin: A population-based study Journal of the National Cancer Institute. 93: 783-789. PMID 11353789 DOI: 10.1093/jnci/93.10.783  0.36
2001 Kowalski TJ, Liu SM, Leibel RL, Chua SC. Transgenic complementation of leptin-receptor deficiency. I. Rescue of the obesity/diabetes phenotype of LEPR-null mice expressing a LEPR-B transgene. Diabetes. 50: 425-35. PMID 11272157 DOI: 10.2337/DIABETES.50.2.425  0.36
2000 Brown JA, Chua SC, Liu SM, Andrews MT, Vandenbergh JG. Spontaneous mutation in the db gene results in obesity and diabetes in CD-1 outbred mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 278: R320-30. PMID 10666131 DOI: 10.1152/ajpregu.2000.278.2.R320  0.36
1999 Wu-Peng S, Rosenbaum M, Nicolson M, Chua SC, Leibel RL. Effects of exogenous gonadal steroids on leptin homeostasis in rats Obesity Research. 7: 586-592. PMID 10574518 DOI: 10.1002/j.1550-8528.1999.tb00718.x  0.36
1998 Schreyer SA, Chua SC, Leboeuf RC. Obesity and diabetes in TNF-α receptor-deficient mice Journal of Clinical Investigation. 102: 402-411. PMID 9664082 DOI: 10.1172/Jci2849  0.36
1997 White DW, Wang DW, Chua SC, Morgenstern JP, Leibel RL, Baumann H, Tartaglia LA. Constitutive and impaired signaling of leptin receptors containing the Gln --> Pro extracellular domain fatty mutation. Proceedings of the National Academy of Sciences of the United States of America. 94: 10657-62. PMID 9380691 DOI: 10.1073/Pnas.94.20.10657  0.36
1997 Ware ML, Fox JW, González JL, Davis NM, Lambert de Rouvroit C, Russo CJ, Chua SC, Goffinet AM, Walsh CA. Aberrant splicing of a mouse disabled homolog, mdab1, in the scrambler mouse. Neuron. 19: 239-49. PMID 9292716 DOI: 10.1016/S0896-6273(00)80936-8  0.36
1997 Chung WK, Zheng M, Chua M, Kershaw E, Power-Kehoe L, Tsuji M, Wu-Peng XS, Williams J, Chua SC, Leibel RL. Genetic modifiers of Lepr(fa) associated with variability in insulin production and susceptibility to NIDDM Genomics. 41: 332-344. PMID 9169130 DOI: 10.1006/geno.1997.4672  0.36
1995 Green ED, Maffei M, Braden VV, Proenca R, DeSilva U, Zhang Y, Chua SC, Leibel RL, Weissenbach J, Friedman JM. The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7 Genome Research. 5: 5-12. PMID 8717050 DOI: 10.1101/Gr.5.1.5  0.36
1995 Kershaw EE, Chua SC, Williams JA, Murphy EM, Leibel RL. Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus. Genomics. 27: 149-54. PMID 7665162 DOI: 10.1006/geno.1995.1017  0.36
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