Year |
Citation |
Score |
2013 |
Kahle KT, Deeb TZ, Puskarjov M, Silayeva L, Liang B, Kaila K, Moss SJ. Modulation of neuronal activity by phosphorylation of the K-Cl cotransporter KCC2. Trends in Neurosciences. 36: 726-37. PMID 24139641 DOI: 10.1016/J.Tins.2013.08.006 |
0.315 |
|
2013 |
Baptista-Hon DT, Deeb TZ, Lambert JJ, Peters JA, Hales TG. The minimum M3-M4 loop length of neurotransmitter-activated pentameric receptors is critical for the structural integrity of cytoplasmic portals. The Journal of Biological Chemistry. 288: 21558-68. PMID 23740249 DOI: 10.1074/Jbc.M113.481689 |
0.665 |
|
2013 |
Deeb TZ, Nakamura Y, Frost GD, Davies PA, Moss SJ. Disrupted Cl(-) homeostasis contributes to reductions in the inhibitory efficacy of diazepam during hyperexcited states. The European Journal of Neuroscience. 38: 2453-67. PMID 23627375 DOI: 10.1111/ejn.12241 |
0.319 |
|
2012 |
Deeb TZ, Maguire J, Moss SJ. Possible alterations in GABAA receptor signaling that underlie benzodiazepine-resistant seizures. Epilepsia. 53: 79-88. PMID 23216581 DOI: 10.1111/Epi.12037 |
0.374 |
|
2012 |
Othman NA, Gallacher M, Deeb TZ, Baptista-Hon DT, Perry DC, Hales TG. Influences on blockade by t-butylbicyclo-phosphoro-thionate of GABA(A) receptor spontaneous gating, agonist activation and desensitization. The Journal of Physiology. 590: 163-78. PMID 22083597 DOI: 10.1113/Jphysiol.2011.213249 |
0.651 |
|
2012 |
Baptista-Hon DT, Deeb TZ, Othman NA, Sharp D, Hales TG. The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine. British Journal of Pharmacology. 165: 693-704. PMID 21740409 DOI: 10.1111/J.1476-5381.2011.01582.X |
0.679 |
|
2011 |
Deeb TZ, Lee HH, Walker JA, Davies PA, Moss SJ. Hyperpolarizing GABAergic transmission depends on KCC2 function and membrane potential. Channels (Austin, Tex.). 5: 475-81. PMID 22082832 DOI: 10.4161/chan.5.6.17952 |
0.332 |
|
2011 |
Lee HH, Deeb TZ, Walker JA, Davies PA, Moss SJ. NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents. Nature Neuroscience. 14: 736-43. PMID 21532577 DOI: 10.1038/nn.2806 |
0.365 |
|
2010 |
Wu DF, Othman NA, Sharp D, Mahendra A, Deeb TZ, Hales TG. A conserved cysteine residue in the third transmembrane domain is essential for homomeric 5-HT3 receptor function. The Journal of Physiology. 588: 603-16. PMID 19933756 DOI: 10.1113/Jphysiol.2009.181719 |
0.692 |
|
2009 |
Deeb TZ, Sharp D, Hales TG. Direct subunit-dependent multimodal 5-hydroxytryptamine3 receptor antagonism by methadone. Molecular Pharmacology. 75: 908-17. PMID 19131665 DOI: 10.1124/Mol.108.053322 |
0.762 |
|
2008 |
Livesey MR, Cooper MA, Deeb TZ, Carland JE, Kozuska J, Hales TG, Lambert JJ, Peters JA. Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor. The Journal of Biological Chemistry. 283: 19301-13. PMID 18474595 DOI: 10.1074/Jbc.M802406200 |
0.66 |
|
2007 |
Deeb TZ, Carland JE, Cooper MA, Livesey MR, Lambert JJ, Peters JA, Hales TG. Dynamic modification of a mutant cytoplasmic cysteine residue modulates the conductance of the human 5-HT3A receptor. The Journal of Biological Chemistry. 282: 6172-82. PMID 17200121 DOI: 10.1074/Jbc.M607698200 |
0.739 |
|
2007 |
McCartney MR, Deeb TZ, Henderson TN, Hales TG. Tonically active GABAA receptors in hippocampal pyramidal neurons exhibit constitutive GABA-independent gating. Molecular Pharmacology. 71: 539-48. PMID 17090706 DOI: 10.1124/Mol.106.028597 |
0.718 |
|
2006 |
Peters JA, Carland JE, Cooper MA, Livesey MR, Deeb TZ, Hales TG, Lambert JJ. Novel structural determinants of single-channel conductance in nicotinic acetylcholine and 5-hydroxytryptamine type-3 receptors. Biochemical Society Transactions. 34: 882-6. PMID 17052220 DOI: 10.1042/Bst0340882 |
0.727 |
|
2006 |
Hales TG, Deeb TZ, Tang H, Bollan KA, King DP, Johnson SJ, Connolly CN. An asymmetric contribution to gamma-aminobutyric type A receptor function of a conserved lysine within TM2-3 of alpha1, beta2, and gamma2 subunits. The Journal of Biological Chemistry. 281: 17034-43. PMID 16627470 DOI: 10.1074/Jbc.M603599200 |
0.724 |
|
2006 |
Hales TG, Dunlop JI, Deeb TZ, Carland JE, Kelley SP, Lambert JJ, Peters JA. Common determinants of single channel conductance within the large cytoplasmic loop of 5-hydroxytryptamine type 3 and alpha4beta2 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 281: 8062-71. PMID 16407231 DOI: 10.1074/Jbc.M513222200 |
0.684 |
|
Low-probability matches (unlikely to be authored by this person) |
2016 |
Nakamura Y, Morrow DH, Modgil A, Huyghe D, Deeb TZ, Lumb MJ, Davies PA, Moss SJ. Proteomic characterization of inhibitory synapses using a novel pHluorin-tagged GABAAR α2 subunit knock-in mouse. The Journal of Biological Chemistry. PMID 27044742 DOI: 10.1074/Jbc.M116.724443 |
0.299 |
|
2017 |
Kang JY, Chadchankar J, Vien TN, Mighdoll MI, Hyde TM, Mather RJ, Deeb TZ, Pangalos MN, Brandon NJ, Dunlop J, Moss SJ. Deficits in the activity of presynaptic γ-Aminobutyric acid type B receptors contribute to altered neuronal excitability in Fragile X Syndrome. The Journal of Biological Chemistry. PMID 28213518 DOI: 10.1074/jbc.M116.772541 |
0.285 |
|
2018 |
Hines RM, Maric HM, Hines DJ, Modgil A, Panzanelli P, Nakamura Y, Nathanson AJ, Cross A, Deeb T, Brandon NJ, Davies P, Fritschy JM, Schindelin H, Moss SJ. Developmental seizures and mortality result from reducing GABA receptor α2-subunit interaction with collybistin. Nature Communications. 9: 3130. PMID 30087324 DOI: 10.1038/S41467-018-05481-1 |
0.278 |
|
2015 |
Sivakumaran S, Cardarelli RA, Maguire J, Kelley MR, Silayeva L, Morrow DH, Mukherjee J, Moore YE, Mather RJ, Duggan ME, Brandon NJ, Dunlop J, Zicha S, Moss SJ, Deeb TZ. Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 8291-6. PMID 26019342 DOI: 10.1523/Jneurosci.5205-14.2015 |
0.263 |
|
2014 |
Terunuma M, Revilla-Sanchez R, Quadros IM, Deng Q, Deeb TZ, Lumb M, Sicinski P, Haydon PG, Pangalos MN, Moss SJ. Postsynaptic GABAB receptor activity regulates excitatory neuronal architecture and spatial memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 804-16. PMID 24431439 DOI: 10.1523/Jneurosci.3320-13.2013 |
0.25 |
|
2017 |
Cardarelli RA, Jones K, Pisella LI, Wobst HJ, McWilliams LJ, Sharpe PM, Burnham MP, Baker DJ, Chudotvorova I, Guyot J, Silayeva L, Morrow DH, Dekker N, Zicha S, Davies PA, ... ... Deeb TZ, et al. The small molecule CLP257 does not modify activity of the K+-Cl- co-transporter KCC2 but does potentiate GABAA receptor activity. Nature Medicine. 23: 1394-1396. PMID 29216042 DOI: 10.1038/nm.4442 |
0.229 |
|
2017 |
Moore YE, Kelley MR, Brandon NJ, Deeb TZ, Moss SJ. Seizing Control of KCC2: A New Therapeutic Target for Epilepsy. Trends in Neurosciences. PMID 28803659 DOI: 10.1016/j.tins.2017.06.008 |
0.222 |
|
2018 |
Fan J, Zhao RQ, Parro C, Zhao W, Chou HY, Robert J, Deeb TZ, Raynoschek C, Barichievy S, Engvist O, Maresca M, Hicks R, Meuller J, Moss SJ, Brandon NJ, et al. Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway. Journal of Lipid Research. PMID 29563219 DOI: 10.1194/jlr.M081851 |
0.212 |
|
2017 |
Conway LC, Cardarelli RA, Moore YE, Jones K, McWilliams LJ, Baker DJ, Burnham MP, Bürli RW, Wang Q, Brandon NJ, Moss SJ, Deeb TZ. N-ethylmaleimide increases KCC2 activity by modulating transporter phosphorylation. The Journal of Biological Chemistry. PMID 29092909 DOI: 10.1074/jbc.M117.817841 |
0.206 |
|
2019 |
Moore YE, Conway LC, Wobst HJ, Brandon NJ, Deeb TZ, Moss SJ. Developmental Regulation of KCC2 Phosphorylation Has Long-Term Impacts on Cognitive Function. Frontiers in Molecular Neuroscience. 12: 173. PMID 31396048 DOI: 10.3389/fnmol.2019.00173 |
0.199 |
|
2015 |
Nakamura Y, Darnieder LM, Deeb TZ, Moss SJ. Regulation of GABAARs by phosphorylation. Advances in Pharmacology (San Diego, Calif.). 72: 97-146. PMID 25600368 DOI: 10.1016/bs.apha.2014.11.008 |
0.193 |
|
2014 |
Kahle KT, Merner ND, Friedel P, Silayeva L, Liang B, Khanna A, Shang Y, Lachance-Touchette P, Bourassa C, Levert A, Dion PA, Walcott B, Spiegelman D, Dionne-Laporte A, Hodgkinson A, ... ... Deeb TZ, et al. Genetically encoded impairment of neuronal KCC2 cotransporter function in human idiopathic generalized epilepsy. Embo Reports. 15: 766-74. PMID 24928908 DOI: 10.15252/Embr.201438840 |
0.193 |
|
2016 |
Trattnig SM, Gasiorek A, Deeb TZ, Ortiz EJ, Moss SJ, Jensen AA, Davies PA. Copper and protons directly activate the zinc-activated channel. Biochemical Pharmacology. PMID 26872532 DOI: 10.1016/j.bcp.2016.02.004 |
0.183 |
|
2016 |
Kelley MR, Deeb TZ, Brandon NJ, Dunlop J, Davies PA, Moss SJ. Compromising KCC2 transporter activity enhances the development of continuous seizure activity. Neuropharmacology. PMID 27108931 DOI: 10.1016/j.neuropharm.2016.04.029 |
0.176 |
|
2015 |
Silayeva L, Deeb TZ, Hines RM, Kelley MR, Munoz MB, Lee HH, Brandon NJ, Dunlop J, Maguire J, Davies PA, Moss SJ. KCC2 activity is critical in limiting the onset and severity of status epilepticus. Proceedings of the National Academy of Sciences of the United States of America. 112: 3523-8. PMID 25733865 DOI: 10.1073/Pnas.1415126112 |
0.172 |
|
2017 |
Mukherjee J, Cardarelli RA, Cantaut-Belarif Y, Deeb TZ, Srivastava DP, Tyagarajan SK, Pangalos MN, Triller A, Maguire J, Brandon NJ, Moss SJ. Estradiol modulates the efficacy of synaptic inhibition by decreasing the dwell time of GABAA receptors at inhibitory synapses. Proceedings of the National Academy of Sciences of the United States of America. PMID 29078280 DOI: 10.1073/Pnas.1705075114 |
0.166 |
|
2021 |
Lee KL, Abiraman K, Lucaj C, Ollerhead TA, Brandon NJ, Deeb TZ, Maguire J, Moss SJ. Inhibiting with-no-lysine kinases enhances K+/Cl- cotransporter 2 activity and limits status epilepticus. Brain : a Journal of Neurology. PMID 34528073 DOI: 10.1093/brain/awab343 |
0.154 |
|
2018 |
Moore YE, Deeb TZ, Chadchankar H, Brandon NJ, Moss SJ. Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures. Proceedings of the National Academy of Sciences of the United States of America. PMID 30224498 DOI: 10.1073/Pnas.1810134115 |
0.152 |
|
2017 |
Agez M, Schultz P, Medina I, Baker DJ, Burnham MP, Cardarelli RA, Conway LC, Garnier K, Geschwindner S, Gunnarsson A, McCall EJ, Frechard A, Audebert S, Deeb TZ, Moss SJ, et al. Molecular architecture of potassium chloride co-transporter KCC2. Scientific Reports. 7: 16452. PMID 29184062 DOI: 10.1038/s41598-017-15739-1 |
0.14 |
|
2023 |
Jarvis R, Josephine Ng SF, Nathanson AJ, Cardarelli RA, Abiraman K, Wade F, Evans-Strong A, Fernandez-Campa MP, Deeb TZ, Smalley JL, Jamier T, Gurrell IK, McWilliams L, Kawatkar A, Conway LC, et al. Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice. Cell Reports. Medicine. 100957. PMID 36889319 DOI: 10.1016/j.xcrm.2023.100957 |
0.129 |
|
2020 |
Smalley JL, Kontou G, Choi C, Ren Q, Albrecht D, Abiraman K, Santos MAR, Bope CE, Deeb TZ, Davies PA, Brandon NJ, Moss SJ. Isolation and Characterization of Multi-Protein Complexes Enriched in the K-Cl Co-transporter 2 From Brain Plasma Membranes. Frontiers in Molecular Neuroscience. 13: 563091. PMID 33192291 DOI: 10.3389/fnmol.2020.563091 |
0.115 |
|
2019 |
Plumbly W, Brandon N, Deeb TZ, Hall J, Harwood AJ. L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks. Scientific Reports. 9: 13810. PMID 31554851 DOI: 10.1038/s41598-019-50226-9 |
0.108 |
|
2018 |
Kelley MR, Cardarelli RA, Smalley JL, Ollerhead TA, Andrew PM, Brandon NJ, Deeb TZ, Moss SJ. Locally Reducing KCC2 Activity in the Hippocampus is Sufficient to Induce Temporal Lobe Epilepsy. Ebiomedicine. PMID 29884458 DOI: 10.1016/j.ebiom.2018.05.029 |
0.103 |
|
2019 |
Tejeda GS, Whiteley EL, Deeb TZ, Bürli RW, Moss SJ, Sheridan E, Brandon NJ, Baillie GS. Chorea-related mutations in PDE10A result in aberrant compartmentalization and functionality of the enzyme. Proceedings of the National Academy of Sciences of the United States of America. PMID 31871190 DOI: 10.1073/pnas.1916398117 |
0.096 |
|
2017 |
Wobst HJ, Wesolowski SS, Chadchankar J, Delsing L, Jacobsen S, Mukherjee J, Deeb TZ, Dunlop J, Brandon NJ, Moss SJ. Cytoplasmic Relocalization of TAR DNA-Binding Protein 43 Is Not Sufficient to Reproduce Cellular Pathologies Associated with ALS In vitro. Frontiers in Molecular Neuroscience. 10: 46. PMID 28286471 DOI: 10.3389/fnmol.2017.00046 |
0.088 |
|
2011 |
Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, et al. Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Developmental Cell. 21: 655-68. PMID 21944720 DOI: 10.1016/J.Devcel.2011.08.009 |
0.04 |
|
Hide low-probability matches. |