Claes Wahlestedt, M.D., Ph.D. - Publications

Affiliations: 
University of Miami School of Medicine University of Miami School of Medicine, Miami, FL, United States 
Area:
molecular neuroscience

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Timmons JA, Anighoro A, Brogan RJ, Stahl J, Wahlestedt C, Farquhar DG, Taylor-King J, Volmar CH, Kraus WE, Phillips SM. A human-based multi-gene signature enables quantitative drug repurposing for metabolic disease. Elife. 11. PMID 35037854 DOI: 10.7554/eLife.68832  0.665
2022 Dennison JL, Volmar CH, Ke D, Wang J, Gravel E, Hammond-Vignini S, Li Z, Timmons JA, Lohse I, Hayward MA, Brothers SP, Wahlestedt C. JOTROL, a Novel Formulation of Resveratrol, Shows Beneficial Effects in the 3xTg-AD Mouse Model. Journal of Alzheimer's Disease : Jad. PMID 35034905 DOI: 10.3233/JAD-215370  0.637
2021 Modarresi F, Pedram Fatemi R, Razavipour SF, Ricciardi N, Makhmutova M, Khoury N, Magistri M, Volmar CH, Wahlestedt C, Faghihi MA. A novel knockout mouse model of the noncoding antisense () gene displays increased endogenous Bdnf protein and improved memory function following exercise. Heliyon. 7: e07570. PMID 34377851 DOI: 10.1016/j.heliyon.2021.e07570  0.627
2021 Dennison JL, Ricciardi NR, Lohse I, Volmar CH, Wahlestedt C. Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research. Journal of Alzheimer's Disease : Jad. PMID 33459720 DOI: 10.3233/JAD-201014  0.612
2020 Kuznetsoff JN, Owens DA, Lopez A, Rodriguez DA, Chee NT, Kurtenbach S, Bilbao D, Roberts ER, Volmar CH, Wahlestedt C, Brothers SP, Harbour JW. Dual screen for efficacy and toxicity identifies HDAC inhibitor with distinctive activity spectrum for BAP1-mutant uveal melanoma. Molecular Cancer Research : McR. PMID 33077485 DOI: 10.1158/1541-7786.MCR-20-0434  0.658
2020 Alvarez-Trotta A, Wang Z, Shersher E, Li B, Long J, Lohse I, Wahlestedt C, El-Rifai W, Robbins DJ, Capobianco AJ. The bromodomain inhibitor IBET-151 attenuates vismodegib-resistant esophageal adenocarcinoma growth through reduction of GLI signaling. Oncotarget. 11: 3174-3187. PMID 32913560 DOI: 10.18632/Oncotarget.27699  0.329
2020 Spriano F, Gaudio E, Cascione L, Tarantelli C, Melle F, Motta G, Priebe V, Rinaldi A, Golino G, Mensah AA, Aresu L, Zucca E, Pileri S, Witcher M, Brown B, ... Wahlestedt C, et al. Antitumor activity of the dual BET and CBP/EP300 inhibitor NEO2734. Blood Advances. 4: 4124-4135. PMID 32882003 DOI: 10.1182/Bloodadvances.2020001879  0.325
2020 Owens DA, Kuznetsov JN, Lopez A, Kurtenbach S, Bilbao D, Roberts ER, Volmar C, Wahlestedt CR, Harbour JW. Abstract 4025: New candidate therapy for BAP1-mutant cancer identified using novel screen Cancer Research. 80: 4025-4025. DOI: 10.1158/1538-7445.Am2020-4025  0.657
2019 Lohse I, Azzam DJ, Al-Ali H, Volmar CH, Brothers SP, Ince TA, Wahlestedt C. Ovarian Cancer Treatment Stratification Using Drug Sensitivity Testing. Anticancer Research. 39: 4023-4030. PMID 31366484 DOI: 10.21873/Anticanres.13558  0.657
2019 Argemi J, Latasa MU, Atkinson SR, Blokhin IO, Massey V, Gue JP, Cabezas J, Lozano JJ, Van Booven D, Bell A, Cao S, Vernetti LA, Arab JP, Ventura-Cots M, Edmunds LR, ... ... Wahlestedt C, et al. Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis. Nature Communications. 10: 3126. PMID 31311938 DOI: 10.1038/S41467-019-11004-3  0.309
2019 Timmons JA, Volmar CH, Crossland H, Phillips BE, Sood S, Janczura KJ, Törmäkangas T, Kujala UM, Kraus WE, Atherton PJ, Wahlestedt C. Longevity-related molecular pathways are subject to midlife "switch" in humans. Aging Cell. e12970. PMID 31168962 DOI: 10.1111/Acel.12970  0.68
2019 Mustafi S, Camarena V, Qureshi R, Yoon H, Volmar CH, Huff TC, Sant DW, Zheng L, Brothers SP, Wahlestedt C, Slingerland J, Wang G. Vitamin C supplementation expands the therapeutic window of BETi for triple negative breast cancer. Ebiomedicine. PMID 30975544 DOI: 10.1016/J.Ebiom.2019.04.006  0.645
2019 Bagheri A, Habibzadeh P, Razavipour SF, Volmar CH, Chee NT, Brothers SP, Wahlestedt C, Mowla SJ, Faghihi MA. HDAC Inhibitors Induce Expression and Promote Neurite Outgrowth in Human Neural Progenitor Cells-Derived Neurons. International Journal of Molecular Sciences. 20. PMID 30841499 DOI: 10.3390/ijms20051109  0.653
2019 Khomtchouk BB, Koehler WC, Van Booven DJ, Wahlestedt C. Optimized functional annotation of ChIP-seq data F1000research. 8: 612. DOI: 10.12688/F1000Research.18966.1  0.307
2018 Janczura KJ, Volmar CH, Wahlestedt C. Purification of H3 and H4 Histone Proteins and the Quantification of Acetylated Histone Marks in Cells and Brain Tissue. Journal of Visualized Experiments : Jove. PMID 30582583 DOI: 10.3791/58648  0.637
2018 Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, et al. Drug and disease signature integration identifies synergistic combinations in glioblastoma. Nature Communications. 9: 5315. PMID 30552330 DOI: 10.1038/S41467-018-07659-Z  0.697
2018 Sartor GC, Malvezzi AM, Kumar A, Andrade NS, Wiedner HJ, Vilca SJ, Janczura KJ, Bagheri A, Al-Ali H, Powell SK, Brown PT, Volmar CH, Foster TC, Zeier Z, Wahlestedt C. Enhancement of BDNF expression and memory by HDAC inhibition requires BET bromodomain reader proteins. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30504275 DOI: 10.1523/Jneurosci.1604-18.2018  0.349
2018 Janczura KJ, Volmar CH, Sartor GC, Rao SJ, Ricciardi NR, Lambert G, Brothers SP, Wahlestedt C. Inhibition of HDAC3 reverses Alzheimer's disease-related pathologies in vitro and in the 3xTg-AD mouse model. Proceedings of the National Academy of Sciences of the United States of America. PMID 30397132 DOI: 10.1073/Pnas.1805436115  0.673
2018 Lohse I, Al-Ali H, Volmar CH, D Alvarez Trotta A, Brothers SP, Capobianco AJ, Wahlestedt C. Ex vivo drug sensitivity testing as a means for drug repurposing in esophageal adenocarcinoma. Plos One. 13: e0203173. PMID 30212533 DOI: 10.1371/Journal.Pone.0203173  0.634
2018 Timmons JA, Atherton PJ, Larsson O, Sood S, Blokhin IO, Brogan RJ, Volmar CH, Josse AR, Slentz C, Wahlestedt C, Phillips SM, Phillips BE, Gallagher IJ, Kraus WE. A coding and non-coding transcriptomic perspective on the genomics of human metabolic disease. Nucleic Acids Research. PMID 29986096 DOI: 10.1093/Nar/Gky570  0.653
2018 Brothers S, Volmar C, Bodamer O, Hayward M, Wahlestedt C. Novel small molecule therapy development for MPS I Molecular Genetics and Metabolism. 123: S26. DOI: 10.1016/J.Ymgme.2017.12.043  0.637
2018 Volmar C, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NT, Desse S, Dorcius D, Cameron MD, Brothers SP, ... Wahlestedt C, et al. 112. Multipronged HDAC Strategy for Alzheimer’s Disease Biological Psychiatry. 83: S46. DOI: 10.1016/J.Biopsych.2018.02.130  0.652
2017 Mustafi S, Camarena V, Volmar CH, Huff TC, Sant DW, Brothers SP, Liu ZJ, Wahlestedt C, Wang G. Vitamin C sensitizes melanoma to BET inhibitors. Cancer Research. PMID 29180474 DOI: 10.1158/0008-5472.Can-17-2040  0.664
2017 Swords RT, Azzam D, Al-Ali H, Lohse I, Volmar CH, Watts JM, Perez A, Rodriguez A, Vargas F, Elias R, Vega F, Zelent A, Brothers SP, Abbasi T, Trent J, ... ... Wahlestedt C, et al. Ex-vivo sensitivity profiling to guide clinical decision making in acute myeloid leukemia: A pilot study. Leukemia Research. 64: 34-41. PMID 29175379 DOI: 10.1016/J.Leukres.2017.11.008  0.635
2017 Yang H, Kurtenbach S, Guo Y, Lohse I, Durante MA, Li J, Li Z, Al-Ali H, Li L, Chen Z, Field MG, Zhang P, Chen S, Yamamoto S, Li Z, ... ... Wahlestedt C, et al. Gain-of-function of ASXL1 truncating protein in the pathogenesis of myeloid malignancies. Blood. PMID 29113963 DOI: 10.1182/Blood-2017-06-789669  0.337
2017 Volmar CH, Salah-Uddin H, Janczura KJ, Halley P, Lambert G, Wodrich A, Manoah S, Patel NH, Sartor GC, Mehta N, Miles NTH, Desse S, Dorcius D, Cameron MD, Brothers SP, ... Wahlestedt C, et al. M344 promotes nonamyloidogenic amyloid precursor protein processing while normalizing Alzheimer's disease genes and improving memory. Proceedings of the National Academy of Sciences of the United States of America. 114: E9135-E9144. PMID 29073110 DOI: 10.1073/Pnas.1707544114  0.658
2017 Sartor GC, Powell SK, Velmeshev D, Lin DY, Magistri M, Wiedner HJ, Malvezzi AM, Andrade NS, Faghihi MA, Wahlestedt C. Cocaine alters Homer1 natural antisense transcript in the nucleus accumbens. Molecular and Cellular Neurosciences. PMID 29055697 DOI: 10.1016/J.Mcn.2017.10.003  0.339
2017 Esanov R, Cabrera GT, Andrade NS, Gendron TF, Brown RH, Benatar M, Wahlestedt C, Mueller C, Zeier Z. A C9ORF72 BAC mouse model recapitulates key epigenetic perturbations of ALS/FTD. Molecular Neurodegeneration. 12: 46. PMID 28606110 DOI: 10.1186/S13024-017-0185-9  0.314
2016 Witt AE, Lee CW, Lee TI, Azzam DJ, Wang B, Caslini C, Petrocca F, Grosso J, Jones M, Cohick EB, Gropper AB, Wahlestedt C, Richardson AL, Shiekhattar R, Young RA, et al. Identification of a cancer stem cell-specific function for the histone deacetylases, HDAC1 and HDAC7, in breast and ovarian cancer. Oncogene. PMID 27694895 DOI: 10.1038/Onc.2016.337  0.341
2016 Magistri M, Velmeshev D, Makhmutova M, Patel P, Sartor GC, Volmar CH, Wahlestedt C, Faghihi MA. The BET-bromodomain inhibitor JQ1 reduces inflammation and tau phosphorylation at Ser396 in the brain of the 3xTg model of Alzheimer's disease. Current Alzheimer Research. PMID 27117003 DOI: 10.2174/1567205013666160427101832  0.657
2016 Laurent GS, Vyatkin Y, Antonets D, Ri M, Qi Y, Saik O, Shtokalo D, de Hoon MJ, Kawaji H, Itoh M, Lassmann T, Arner E, Forrest AR, Nicolas E, ... ... Wahlestedt C, et al. Functional annotation of the vlinc class of non-coding RNAs using systems biology approach. Nucleic Acids Research. PMID 27001520 DOI: 10.1093/Nar/Gkw162  0.32
2016 Volmar CH, Wahlestedt C, Brothers SP. Orphan diseases: state of the drug discovery art. Wiener Medizinische Wochenschrift (1946). PMID 26819216 DOI: 10.1007/s10354-015-0423-0  0.641
2015 Peschansky VJ, Pastori C, Zeier Z, Motti D, Wentzel K, Velmeshev D, Magistri M, Bixby JL, Lemmon VP, Silva JP, Wahlestedt C. Changes in expression of the long non-coding RNA FMR4 associate with altered gene expression during differentiation of human neural precursor cells. Frontiers in Genetics. 6: 263. PMID 26322075 DOI: 10.3389/Fgene.2015.00263  0.35
2015 Pedram Fatemi R, Salah-Uddin S, Modarresi F, Khoury N, Wahlestedt C, Faghihi MA. Screening for Small-Molecule Modulators of Long Noncoding RNA-Protein Interactions Using AlphaScreen. Journal of Biomolecular Screening. 20: 1132-41. PMID 26173710 DOI: 10.1177/1087057115594187  0.359
2015 Pastori C, Kapranov P, Penas C, Peschansky V, Volmar CH, Sarkaria JN, Bregy A, Komotar R, St Laurent G, Ayad NG, Wahlestedt C. The Bromodomain protein BRD4 controls HOTAIR, a long noncoding RNA essential for glioblastoma proliferation. Proceedings of the National Academy of Sciences of the United States of America. 112: 8326-31. PMID 26111795 DOI: 10.1073/Pnas.1424220112  0.704
2015 Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, ... Wahlestedt C, et al. Bromodomain inhibitors regulate the C9ORF72 locus in ALS. Experimental Neurology. 271: 241-50. PMID 26099177 DOI: 10.1016/J.Expneurol.2015.06.017  0.688
2015 Yamanaka Y, Faghihi MA, Magistri M, Alvarez-Garcia O, Lotz M, Wahlestedt C. Antisense RNA controls LRP1 Sense transcript expression through interaction with a chromatin-associated protein, HMGB2. Cell Reports. 11: 967-76. PMID 25937287 DOI: 10.1016/J.Celrep.2015.04.011  0.372
2015 Swords RT, Brothers S, Ayad N, Perez A, Watts JM, Vargas F, Elias R, Rodriguez A, Johnstone S, Albert J, Collard J, Zelent A, Wahlestedt C. The BET Bromodomain Inhibitors EP11313 and EP11336 Have Potent Anti-Leukemic Activity in Acute Myeloid Leukemia (AML) and Augment the Effects of All-Trans-Retinoic Acid (AtRA) in Vitro Blood. 126: 2552-2552. DOI: 10.1182/Blood.V126.23.2552.2552  0.337
2015 Azzam D, Volmar C, Hassan A, Perez A, Watts JM, Vargas F, Elias R, Vega F, Zelent A, Cogle CR, Wahlestedt C, Swords RT. A Patient-Specific Ex Vivo Screening Platform for Personalized Acute Myeloid Leukemia (AML) Therapy Blood. 126: 1352-1352. DOI: 10.1182/Blood.V126.23.1352.1352  0.676
2015 Pastori C, Kapranov P, Penas C, Laurent GS, Ayad N, Wahlestedt C. Abstract 4764: The Bromodomain inhibitors regulate long noncoding RNAs controlling glioblastoma progression Cancer Research. 75: 4764-4764. DOI: 10.1158/1538-7445.Am2015-4764  0.392
2015 Volmar C, Wahlestedt C. Histone deacetylases (HDACs) and brain function Neuroepigenetics. 1: 20-27. DOI: 10.1016/j.nepig.2014.10.002  0.623
2015 Zeier Z, Esanov R, Belle KC, Volmar CH, Johnstone AL, Halley P, DeRosa BA, Khoury N, van Blitterswijk M, Rademakers R, Albert J, Brothers SP, Wuu J, Dykxhoorn DM, Benatar M, ... Wahlestedt C, et al. Bromodomain inhibitors regulate the C9ORF72 locus in ALS Experimental Neurology. 271: 241-250. DOI: 10.1016/j.expneurol.2015.06.017  0.616
2014 Long J, Li B, Rodriguez-Blanco J, Pastori C, Volmar CH, Wahlestedt C, Capobianco A, Bai F, Pei XH, Ayad NG, Robbins DJ. The BET bromodomain inhibitor I-BET151 acts downstream of smoothened protein to abrogate the growth of hedgehog protein-driven cancers. The Journal of Biological Chemistry. 289: 35494-502. PMID 25355313 DOI: 10.1074/Jbc.M114.595348  0.689
2014 Plotkin A, Volmar CH, Wahlestedt C, Ayad N, El-Ashry D. Transcriptional repression of ER through hMAPK dependent histone deacetylation by class I HDACs. Breast Cancer Research and Treatment. 147: 249-63. PMID 25129342 DOI: 10.1007/S10549-014-3093-5  0.638
2014 Kang MJ, Abdelmohsen K, Hutchison ER, Mitchell SJ, Grammatikakis I, Guo R, Noh JH, Martindale JL, Yang X, Lee EK, Faghihi MA, Wahlestedt C, Troncoso JC, Pletnikova O, Perrone-Bizzozero N, et al. HuD regulates coding and noncoding RNA to induce APP→Aβ processing. Cell Reports. 7: 1401-9. PMID 24857657 DOI: 10.1016/J.Celrep.2014.04.050  0.326
2014 Peschansky VJ, Wahlestedt C. Non-coding RNAs as direct and indirect modulators of epigenetic regulation. Epigenetics : Official Journal of the Dna Methylation Society. 9: 3-12. PMID 24739571 DOI: 10.4161/Epi.27473  0.358
2014 Pastori C, Daniel M, Penas C, Volmar CH, Johnstone AL, Brothers SP, Graham RM, Allen B, Sarkaria JN, Komotar RJ, Wahlestedt C, Ayad NG. BET bromodomain proteins are required for glioblastoma cell proliferation. Epigenetics : Official Journal of the Dna Methylation Society. 9: 611-20. PMID 24496381 DOI: 10.4161/Epi.27906  0.684
2014 Pastori C, Peschansky VJ, Barbouth D, Mehta A, Silva JP, Wahlestedt C. Comprehensive analysis of the transcriptional landscape of the human FMR1 gene reveals two new long noncoding RNAs differentially expressed in Fragile X syndrome and Fragile X-associated tremor/ataxia syndrome. Human Genetics. 133: 59-67. PMID 24005575 DOI: 10.1007/S00439-013-1356-6  0.327
2014 Pastori C, Penas C, Kapranov P, Laurent GS, Zhang M, Ayad N, Wahlestedt C. Abstract LB-114: The long noncoding RNA HOTAIR promotes glioblastoma cell proliferation Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Lb-114  0.393
2014 Johnstone S, Johhnsone A, Penas C, Stathias V, Brothers S, Ayad N, Wahlestedt C, Albert J. EG-04 * DEVELOPMENT OF HIGHLY POTENT, SELECTIVE BET BROMODOMAIN INHIBITORS THAT ARE CNS PENETRANT AND EFFECTIVE IN RODENT MODELS OF BRAIN CANCER Neuro-Oncology. 16: v75-v75. DOI: 10.1093/Neuonc/Nou254.4  0.366
2014 Pastori C, Kapranov P, Penas C, Laurent GS, Ayad N, Wahlestedt C. EG-10 * LONG NON-CODING RNAs IN GLIOBLASTOMA Neuro-Oncology. 16: v77-v77. DOI: 10.1093/Neuonc/Nou254.10  0.388
2013 Khorkova O, Hsiao J, Wahlestedt C. Oligonucleotides for upregulating gene expression. Pharmaceutical Patent Analyst. 2: 215-29. PMID 24237027 DOI: 10.4155/Ppa.13.4  0.332
2013 Clarke J, Penas C, Pastori C, Komotar RJ, Bregy A, Shah AH, Wahlestedt C, Ayad NG. Epigenetic pathways and glioblastoma treatment. Epigenetics : Official Journal of the Dna Methylation Society. 8: 785-95. PMID 23807265 DOI: 10.4161/Epi.25440  0.308
2012 Peschansky VJ, Liang Z, Wahlestedt C. RNAi joins the "Singles Club". Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 2010-1. PMID 23131851 DOI: 10.1038/Mt.2012.218  0.347
2012 Sartor GC, St Laurent G, Wahlestedt C. The Emerging Role of Non-Coding RNAs in Drug Addiction. Frontiers in Genetics. 3: 106. PMID 22737160 DOI: 10.3389/Fgene.2012.00106  0.342
2012 Magistri M, Faghihi MA, St Laurent G, Wahlestedt C. Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts. Trends in Genetics : Tig. 28: 389-96. PMID 22541732 DOI: 10.1016/J.Tig.2012.03.013  0.359
2012 Modarresi F, Faghihi MA, Lopez-Toledano MA, Fatemi RP, Magistri M, Brothers SP, van der Brug MP, Wahlestedt C. Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation. Nature Biotechnology. 30: 453-9. PMID 22446693 DOI: 10.1038/Nbt.2158  0.357
2011 Modarresi F, Faghihi MA, Patel NS, Sahagan BG, Wahlestedt C, Lopez-Toledano MA. Knockdown of BACE1-AS Nonprotein-Coding Transcript Modulates Beta-Amyloid-Related Hippocampal Neurogenesis. International Journal of Alzheimer's Disease. 2011: 929042. PMID 21785702 DOI: 10.4061/2011/929042  0.34
2011 Clark MB, Amaral PP, Schlesinger FJ, Dinger ME, Taft RJ, Rinn JL, Ponting CP, Stadler PF, Morris KV, Morillon A, Rozowsky JS, Gerstein MB, Wahlestedt C, Hayashizaki Y, Carninci P, et al. The reality of pervasive transcription. Plos Biology. 9: e1000625; discussion. PMID 21765801 DOI: 10.1371/Journal.Pbio.1000625  0.302
2010 Faghihi MA, Kocerha J, Modarresi F, Engström PG, Chalk AM, Brothers SP, Koesema E, St Laurent G, Wahlestedt C. RNAi screen indicates widespread biological function for human natural antisense transcripts. Plos One. 5. PMID 20957177 DOI: 10.1371/Journal.Pone.0013177  0.339
2010 Silva JP, Wahlestedt C. Role of Sirtuin 1 in metabolic regulation. Drug Discovery Today. 15: 781-91. PMID 20621197 DOI: 10.1016/J.Drudis.2010.07.001  0.303
2010 Faghihi MA, Zhang M, Huang J, Modarresi F, Van der Brug MP, Nalls MA, Cookson MR, St-Laurent G, Wahlestedt C. Evidence for natural antisense transcript-mediated inhibition of microRNA function. Genome Biology. 11: R56. PMID 20507594 DOI: 10.1186/Gb-2010-11-5-R56  0.313
2009 St Laurent G, Faghihi MA, Wahlestedt C. Non-coding RNA transcripts: sensors of neuronal stress, modulators of synaptic plasticity, and agents of change in the onset of Alzheimer's disease. Neuroscience Letters. 466: 81-8. PMID 19699259 DOI: 10.1016/J.Neulet.2009.08.032  0.34
2009 Faghihi MA, Wahlestedt C. Regulatory roles of natural antisense transcripts. Nature Reviews. Molecular Cell Biology. 10: 637-43. PMID 19638999 DOI: 10.1038/Nrm2738  0.317
2009 Suzuki H, Forrest AR, van Nimwegen E, Daub CO, Balwierz PJ, Irvine KM, Lassmann T, Ravasi T, Hasegawa Y, de Hoon MJ, Katayama S, Schroder K, Carninci P, Tomaru Y, ... ... Wahlestedt C, et al. The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line. Nature Genetics. 41: 553-62. PMID 19377474 DOI: 10.1038/Ng.375  0.3
2008 Shan G, Li Y, Zhang J, Li W, Szulwach KE, Duan R, Faghihi MA, Khalil AM, Lu L, Paroo Z, Chan AW, Shi Z, Liu Q, Wahlestedt C, He C, et al. A small molecule enhances RNA interference and promotes microRNA processing. Nature Biotechnology. 26: 933-40. PMID 18641635 DOI: 10.1038/Nbt.1481  0.327
2008 Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan TE, Finch CE, St Laurent G, Kenny PJ, Wahlestedt C. Expression of a noncoding RNA is elevated in Alzheimer's disease and drives rapid feed-forward regulation of beta-secretase. Nature Medicine. 14: 723-30. PMID 18587408 DOI: 10.1038/Nm1784  0.337
2008 Dahlgren C, Zhang HY, Du Q, Grahn M, Norstedt G, Wahlestedt C, Liang Z. Analysis of siRNA specificity on targets with double-nucleotide mismatches. Nucleic Acids Research. 36: e53. PMID 18420656 DOI: 10.1093/Nar/Gkn190  0.305
2008 Hong J, Wei N, Chalk A, Wang J, Song Y, Yi F, Qiao RP, Sonnhammer EL, Wahlestedt C, Liang Z, Du Q. Focusing on RISC assembly in mammalian cells. Biochemical and Biophysical Research Communications. 368: 703-8. PMID 18252196 DOI: 10.1016/J.Bbrc.2008.01.116  0.305
2008 Khalil AM, Faghihi MA, Modarresi F, Brothers SP, Wahlestedt C. A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome. Plos One. 3: e1486. PMID 18213394 DOI: 10.1371/Journal.Pone.0001486  0.34
2007 Timmons JA, Wennmalm K, Larsson O, Walden TB, Lassmann T, Petrovic N, Hamilton DL, Gimeno RE, Wahlestedt C, Baar K, Nedergaard J, Cannon B. Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages. Proceedings of the National Academy of Sciences of the United States of America. 104: 4401-6. PMID 17360536 DOI: 10.1073/Pnas.0610615104  0.301
2006 Larsson O, Perlman DM, Fan D, Reilly CS, Peterson M, Dahlgren C, Liang Z, Li S, Polunovsky VA, Wahlestedt C, Bitterman PB. Apoptosis resistance downstream of eIF4E: posttranscriptional activation of an anti-apoptotic transcript carrying a consensus hairpin structure. Nucleic Acids Research. 34: 4375-86. PMID 16936314 DOI: 10.1093/Nar/Gkl558  0.319
2006 Zhang HY, Du Q, Wahlestedt C, Liang Z. RNA Interference with chemically modified siRNA. Current Topics in Medicinal Chemistry. 6: 893-900. PMID 16787282 DOI: 10.2174/156802606777303676  0.333
2006 Wahlestedt C. Natural antisense and noncoding RNA transcripts as potential drug targets. Drug Discovery Today. 11: 503-8. PMID 16713901 DOI: 10.1016/J.Drudis.2006.04.013  0.343
2006 Faghihi MA, Wahlestedt C. RNA interference is not involved in natural antisense mediated regulation of gene expression in mammals. Genome Biology. 7: R38. PMID 16684369 DOI: 10.1186/Gb-2006-7-5-R38  0.333
2006 Engström PG, Suzuki H, Ninomiya N, Akalin A, Sessa L, Lavorgna G, Brozzi A, Luzi L, Tan SL, Yang L, Kunarso G, Ng EL, Batalov S, Wahlestedt C, Kai C, et al. Complex Loci in human and mouse genomes. Plos Genetics. 2: e47. PMID 16683030 DOI: 10.1371/Journal.Pgen.0020047  0.3
2006 Frith MC, Wilming LG, Forrest A, Kawaji H, Tan SL, Wahlestedt C, Bajic VB, Kai C, Kawai J, Carninci P, Hayashizaki Y, Bailey TL, Huminiecki L. Pseudo-messenger RNA: phantoms of the transcriptome. Plos Genetics. 2: e23. PMID 16683022 DOI: 10.1371/Journal.Pgen.0020023  0.335
2006 Volmar C, Janczura KJ, Lambert G, Salah-Uddin H, Halley P, Sartor GC, Brothers SP, Wahlestedt C. P4-220: MULTIFACTORIAL EPIGENETIC STRATEGY FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P1527-P1527. DOI: 10.1016/J.Jalz.2018.07.041  0.652
2005 Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, ... ... Wahlestedt C, et al. Antisense transcription in the mammalian transcriptome. Science (New York, N.Y.). 309: 1564-6. PMID 16141073 DOI: 10.1126/Science.1112009  0.335
2005 Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, ... ... Wahlestedt C, et al. The transcriptional landscape of the mammalian genome. Science (New York, N.Y.). 309: 1559-63. PMID 16141072 DOI: 10.1126/Science.1112014  0.309
2005 Timmons JA, Larsson O, Jansson E, Fischer H, Gustafsson T, Greenhaff PL, Ridden J, Rachman J, Peyrard-Janvid M, Wahlestedt C, Sundberg CJ. Human muscle gene expression responses to endurance training provide a novel perspective on Duchenne muscular dystrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 750-60. PMID 15857889 DOI: 10.1096/Fj.04-1980Com  0.3
2005 Du Q, Thonberg H, Wang J, Wahlestedt C, Liang Z. A systematic analysis of the silencing effects of an active siRNA at all single-nucleotide mismatched target sites. Nucleic Acids Research. 33: 1671-7. PMID 15781493 DOI: 10.1093/Nar/Gki647  0.303
2005 Chen M, Zhang L, Zhang HY, Xiong X, Wang B, Du Q, Lu B, Wahlestedt C, Liang Z. A universal plasmid library encoding all permutations of small interfering RNA. Proceedings of the National Academy of Sciences of the United States of America. 102: 2356-61. PMID 15695593 DOI: 10.1073/Pnas.0401549101  0.324
2005 Elmén J, Thonberg H, Ljungberg K, Frieden M, Westergaard M, Xu Y, Wahren B, Liang Z, Ørum H, Koch T, Wahlestedt C. Locked nucleic acid (LNA) mediated improvements in siRNA stability and functionality. Nucleic Acids Research. 33: 439-47. PMID 15653644 DOI: 10.1093/Nar/Gki193  0.326
2005 Pang KC, Stephen S, Engström PG, Tajul-Arifin K, Chen W, Wahlestedt C, Lenhard B, Hayashizaki Y, Mattick JS. RNAdb--a comprehensive mammalian noncoding RNA database. Nucleic Acids Research. 33: D125-30. PMID 15608161 DOI: 10.1093/Nar/Gki089  0.337
2004 Thonberg H, Schéele CC, Dahlgren C, Wahlestedt C. Characterization of RNA interference in rat PC12 cells: requirement of GERp95. Biochemical and Biophysical Research Communications. 318: 927-34. PMID 15147961 DOI: 10.1016/J.Bbrc.2004.04.119  0.31
2004 Larsson O, Scheele C, Liang Z, Moll J, Karlsson C, Wahlestedt C. Kinetics of senescence-associated changes of gene expression in an epithelial, temperature-sensitive SV40 large T antigen model. Cancer Research. 64: 482-9. PMID 14744760 DOI: 10.1158/0008-5472.Can-03-1872  0.302
2002 Okazaki Y, Furuno M, Kasukawa T, Adachi J, Bono H, Kondo S, Nikaido I, Osato N, Saito R, Suzuki H, Yamanaka I, Kiyosawa H, Yagi K, Tomaru Y, Hasegawa Y, ... ... Wahlestedt C, et al. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 420: 563-73. PMID 12466851 DOI: 10.1038/Nature01266  0.323
2000 Hoja MR, Wahlestedt C, Höög C. A visual intracellular classification strategy for uncharacterized human proteins. Experimental Cell Research. 259: 239-46. PMID 10942595 DOI: 10.1006/Excr.2000.4948  0.31
1996 Weng G, Feinstein D, Reis D, Wahlestedt C. Neuropeptide Y receptor gene regulation in mouse adrenocortical Y-1 cells. Regulatory Peptides. 63: 53-6. PMID 8795089 DOI: 10.1016/0167-0115(96)00030-4  0.327
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