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Ryan H. Purcell, Ph.D. - Publications

Affiliations: 
2011-2017 Pharmacology Emory University, Atlanta, GA 
 2017- Cell Biology and Genetics Emory University, Atlanta, GA 
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16/337 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Purcell RH, Sefik E, Werner E, King AT, Mosley TJ, Merritt-Garza ME, Chopra P, McEachin ZT, Karne S, Raj N, Vaglio BJ, Sullivan D, Firestein BL, Tilahun K, Robinette MI, et al. Cross-species analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion. Science Advances. 9: eadh0558. PMID 37585521 DOI: 10.1126/sciadv.adh0558  0.742
2023 Purcell RH, Sefik E, Werner E, King AT, Mosley TJ, Merritt-Garza ME, Chopra P, McEachin ZT, Karne S, Raj N, Tilahun K, Robinette M, Warren ST, Wen Z, Faundez V, et al. Cross-species transcriptomic analysis identifies mitochondrial dysregulation as a functional consequence of the schizophrenia-associated 3q29 deletion. Biorxiv : the Preprint Server For Biology. PMID 36747819 DOI: 10.1101/2023.01.27.525748  0.746
2022 Pollak RM, Purcell RH, Rutkowski TP, Malone T, Pachura KJ, Bassell GJ, Epstein MP, Dawson PA, Smith MR, Jones DP, Zwick ME, Warren ST, Caspary T, Weinshenker D, Mulle JG. Metabolic effects of the schizophrenia-associated 3q29 deletion. Translational Psychiatry. 12: 66. PMID 35177588 DOI: 10.1038/s41398-022-01824-1  0.598
2022 Shiu FH, Wong JC, Yamamoto T, Lala T, Purcell RH, Owino S, Zhu D, Van Meir EG, Hall RA, Escayg A. Mice lacking full length Adgrb1 (Bai1) exhibit social deficits, increased seizure susceptibility, and altered brain development. Experimental Neurology. 113994. PMID 35114205 DOI: 10.1016/j.expneurol.2022.113994  0.669
2021 Glassford MR, Purcell RH, Pass S, Murphy MM, Bassell GJ, Mulle JG. Caregiver Perspectives on a Child's Diagnosis of 3q29 Deletion: "We Can't Just Wish This Thing Away". Journal of Developmental and Behavioral Pediatrics : Jdbp. PMID 34320535 DOI: 10.1097/DBP.0000000000000977  0.535
2021 Sefik E, Purcell RH, Walker EF, Bassell GJ, Mulle JG. Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome. Translational Psychiatry. 11: 357. PMID 34131099 DOI: 10.1038/s41398-021-01435-2  0.755
2021 Sefik E, Purcell RH, Walker EF, Bassell GJ, Mulle JG. Convergent and distributed effects of the 3q29 deletion on the human neural transcriptome. Translational Psychiatry. 11: 357. PMID 34131099 DOI: 10.1038/s41398-021-01435-2  0.755
2020 McEachin ZT, Gendron TF, Raj N, García-Murias M, Banerjee A, Purcell RH, Ward PJ, Todd TW, Merritt-Garza ME, Jansen-West K, Hales CM, García-Sobrino T, Quintáns B, Holler CJ, Taylor G, et al. Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36. Neuron. PMID 32375063 DOI: 10.1016/J.Neuron.2020.04.011  0.685
2019 Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG. Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion. Molecular Psychiatry. PMID 30976085 DOI: 10.1038/S41380-019-0413-5  0.646
2019 Pollak R, Purcell R, Rutkowski T, Malone T, Pachura K, Bassell GJ, Epstein MP, Caspary T, Dawson PA, Jones DP, Warren ST, Weinshenker D, Zwick ME, Mulle JG. T11Metabolic Dysfunction As A Contributor To Phenotypes Of The Schizophrenia-Associated 3Q29 Deletion European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2019.08.210  0.618
2019 Sefik E, Purcell R, Bassell GJ, Walker E, Mulle J. M55 WEIGHTED GENE CO-EXPRESSION NETWORK ANALYSIS OF THE HUMAN FRONTAL CORTEX REVEALS NOVEL INSIGHTS INTO THE SCHIZOPHRENIA-ASSOCIATED 3Q29 DELETION SYNDROME European Neuropsychopharmacology. 29: S195. DOI: 10.1016/J.Euroneuro.2019.08.155  0.739
2017 Purcell RH, Hall RA. Adhesion G Protein-Coupled Receptors as Drug Targets. Annual Review of Pharmacology and Toxicology. PMID 28968187 DOI: 10.1146/Annurev-Pharmtox-010617-052933  0.478
2017 Purcell RH, Toro C, Gahl WA, Hall RA. A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2) increases receptor signaling activity. Human Mutation. PMID 28891236 DOI: 10.1002/Humu.23336  0.494
2015 Kishore A, Purcell RH, Nassiri-Toosi Z, Hall RA. Stalk-dependent and stalk-independent signaling by the adhesion G protein-coupled receptors GPR56 (ADGRG1) and BAI1 (ADGRB1). The Journal of Biological Chemistry. PMID 26710850 DOI: 10.1074/Jbc.M115.689349  0.486
2014 Stephenson JR, Purcell RH, Hall RA. The BAI subfamily of adhesion GPCRs: synaptic regulation and beyond. Trends in Pharmacological Sciences. 35: 208-15. PMID 24642458 DOI: 10.1016/J.Tips.2014.02.002  0.621
2010 Lee RS, Tamashiro KL, Yang X, Purcell RH, Harvey A, Willour VL, Huo Y, Rongione M, Wand GS, Potash JB. Chronic corticosterone exposure increases expression and decreases deoxyribonucleic acid methylation of Fkbp5 in mice. Endocrinology. 151: 4332-43. PMID 20668026 DOI: 10.1210/En.2010-0225  0.337
Low-probability matches (unlikely to be authored by this person)
2013 Purcell RH, Papale LA, Makinson CD, Sawyer NT, Schroeder JP, Escayg A, Weinshenker D. Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice. Psychopharmacology. 228: 263-70. PMID 23494229 DOI: 10.1007/S00213-013-3034-8  0.282
2011 Lee RS, Tamashiro KL, Yang X, Purcell RH, Huo Y, Rongione M, Potash JB, Wand GS. A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice. Psychopharmacology. 218: 303-12. PMID 21509501 DOI: 10.1007/S00213-011-2307-3  0.278
2010 Purcell R, Sun B, Pass L, Moran T, Tamashiro K. Gestational stress and high-fat diet effects on maternal behavior, milk composition, pup ingestive behavior and hypothalamic gene expression Appetite. 54: 671. DOI: 10.1016/J.Appet.2010.04.168  0.266
2011 Ewald E, Sun B, Purcell R, Lee R, Potash J, Moran T, Tamashiro K. Maternal high-fat diet during gestation and lactation alters hepatic gene expression in male rat offspring Appetite. 57: S15. DOI: 10.1016/J.Appet.2011.05.166  0.261
2014 Boersma GJ, Lee RS, Cordner ZA, Ewald ER, Purcell RH, Moghadam AA, Tamashiro KL. Prenatal stress decreases Bdnf expression and increases methylation of Bdnf exon IV in rats. Epigenetics : Official Journal of the Dna Methylation Society. 9: 437-47. PMID 24365909 DOI: 10.4161/Epi.27558  0.259
2023 Yilmaz F, Gurusamy U, Mosley TJ, Hallast P, Kim K, Mostovoy Y, Purcell RH, Shaikh TH, Zwick ME, Kwok PY, Lee C, Mulle JG. High level of complexity and global diversity of the 3q29 locus revealed by optical mapping and long-read sequencing. Genome Medicine. 15: 35. PMID 37165454 DOI: 10.1186/s13073-023-01184-5  0.255
2012 Sun B, Purcell RH, Terrillion CE, Yan J, Moran TH, Tamashiro KL. Maternal high-fat diet during gestation or suckling differentially affects offspring leptin sensitivity and obesity. Diabetes. 61: 2833-41. PMID 22751689 DOI: 10.2337/Db11-0957  0.246
2011 Purcell RH, Sun B, Pass LL, Power ML, Moran TH, Tamashiro KL. Maternal stress and high-fat diet effect on maternal behavior, milk composition, and pup ingestive behavior. Physiology & Behavior. 104: 474-9. PMID 21605577 DOI: 10.1016/J.Physbeh.2011.05.012  0.242
2013 Sun B, Liang NC, Ewald ER, Purcell RH, Boersma GJ, Yan J, Moran TH, Tamashiro KL. Early postweaning exercise improves central leptin sensitivity in offspring of rat dams fed high-fat diet during pregnancy and lactation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 305: R1076-84. PMID 24026073 DOI: 10.1152/Ajpregu.00566.2012  0.224
2011 Purcell R, Ewald E, Volk K, Sun B, Liang N, Moran T, Tamashiro K. Short- and long-term effects of olanzapine on food intake and hypothalamic gene expression in female rats Appetite. 57: S35. DOI: 10.1016/J.Appet.2011.05.247  0.224
2015 Purcell RH, Rommelfanger KS. Internet-based brain training games, citizen scientists, and big data: ethical issues in unprecedented virtual territories. Neuron. 86: 356-9. PMID 25905809 DOI: 10.1016/J.Neuron.2015.03.044  0.222
2011 Sun B, Purcell R, Ewald E, Yan J, Moran T, Tamashiro K. Maternal high fat diet during gestation or suckling alters offspring leptin sensitivity prior to weaning Appetite. 57: S42. DOI: 10.1016/J.Appet.2011.05.276  0.219
2010 Sun B, Purcell R, Yan J, Moran T, Tamashiro K. Maternal high fat diet during gestation or suckling differentially affects offspring obesity Appetite. 54: 677. DOI: 10.1016/J.Appet.2010.04.191  0.215
2021 Cable J, Purcell RH, Robinson E, Vorstman JAS, Chung WK, Constantino JN, Sanders SJ, Sahin M, Dolmetsch RE, Shah BM, Thurm A, Martin CL, Bearden CE, Mulle JG. Harnessing rare variants in neuropsychiatric and neurodevelopment disorders-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34342000 DOI: 10.1111/nyas.14658  0.191
1998 Shimoda A, Sugata F, Chen HS, Miller RH, Purcell RH. Evidence for a bidirectional promoter complex within the X gene of woodchuck hepatitis virus. Virus Research. 56: 25-39. PMID 9784063 DOI: 10.1016/S0168-1702(98)00050-1  0.177
2010 Yu C, Boon D, McDonald SL, Myers TG, Tomioka K, Nguyen H, Engle RE, Govindarajan S, Emerson SU, Purcell RH. Pathogenesis of hepatitis E virus and hepatitis C virus in chimpanzees: similarities and differences. Journal of Virology. 84: 11264-78. PMID 20739520 DOI: 10.1128/JVI.01205-10  0.175
2019 Ahlgrim N, Garza K, Hoffman C, Coolidge S, Purcell RH. Select Interviews From the INS Annual Meeting-Keith Humphreys, Tom Insel, Uma Karmarkar, Carl Marci, Ariel Cascio, Winston Chiong, Frederic Gilbert, Cynthia Kubu, and Jonathan Pugh. Ajob Neuroscience. 10: 62-68. PMID 31070549 DOI: 10.1080/21507740.2019.1595773  0.17
2017 Purcell RH, Rommelfanger KS. Biometric Tracking From Professional Athletes to Consumers. The American Journal of Bioethics : Ajob. 17: 72-74. PMID 27996927 DOI: 10.1080/15265161.2016.1251652  0.155
2012 Purcell R. Performance enhancement: To embrace doping in sport is absurd Nature. 488: 157-157. PMID 22874954 DOI: 10.1038/488157A  0.151
2005 Graff J, Nguyen H, Yu C, Elkins WR, St Claire M, Purcell RH, Emerson SU. The open reading frame 3 gene of hepatitis E virus contains a cis-reactive element and encodes a protein required for infection of macaques. Journal of Virology. 79: 6680-9. PMID 15890906 DOI: 10.1128/JVI.79.11.6680-6689.2005  0.148
2011 Parvez MK, Purcell RH, Emerson SU. Hepatitis E virus ORF2 protein over-expressed by baculovirus in hepatoma cells, efficiently encapsidates and transmits the viral RNA to naïve cells. Virology Journal. 8: 159. PMID 21477278 DOI: 10.1186/1743-422X-8-159  0.143
2015 Parekh MB, Rutt BK, Purcell R, Chen Y, Zeineh MM. Ultra-high resolution in-vivo 7.0T structural imaging of the human hippocampus reveals the endfolial pathway. Neuroimage. 112: 1-6. PMID 25701699 DOI: 10.1016/J.Neuroimage.2015.02.029  0.142
1998 Yu M, Emerson SU, Cote P, Shapiro M, Purcell RH. The GDPAL region of the pre-S1 envelope protein is important for morphogenesis of woodchuck hepatitis virus. Hepatology (Baltimore, Md.). 27: 1408-14. PMID 9581699 DOI: 10.1002/hep.510270531  0.137
2011 Kawaguchi K, Faulk K, Purcell RH, Emerson SU. Reproduction in vitro of a quasispecies from a hepatitis C virus-infected patient and determination of factors that influence selection of a dominant species. Journal of Virology. 85: 3408-14. PMID 21270157 DOI: 10.1128/JVI.02554-10  0.137
2002 Su AI, Pezacki JP, Wodicka L, Brideau AD, Supekova L, Thimme R, Wieland S, Bukh J, Purcell RH, Schultz PG, Chisari FV. Genomic analysis of the host response to hepatitis C virus infection. Proceedings of the National Academy of Sciences of the United States of America. 99: 15669-74. PMID 12441396 DOI: 10.1073/Pnas.202608199  0.135
2004 Emerson SU, Nguyen H, Graff J, Stephany DA, Brockington A, Purcell RH. In vitro replication of hepatitis E virus (HEV) genomes and of an HEV replicon expressing green fluorescent protein. Journal of Virology. 78: 4838-46. PMID 15078965 DOI: 10.1128/JVI.78.9.4838-4846.2004  0.134
2005 Graff J, Nguyen H, Kasorndorkbua C, Halbur PG, St Claire M, Purcell RH, Emerson SU. In vitro and in vivo mutational analysis of the 3'-terminal regions of hepatitis e virus genomes and replicons. Journal of Virology. 79: 1017-26. PMID 15613330 DOI: 10.1128/Jvi.79.2.1017-1026.2005  0.131
2004 Huang FF, Sun ZF, Emerson SU, Purcell RH, Shivaprasad HL, Pierson FW, Toth TE, Meng XJ. Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV. The Journal of General Virology. 85: 1609-18. PMID 15166445 DOI: 10.1099/vir.0.79841-0  0.129
2002 Emerson SU, Huang YK, Nguyen H, Brockington A, Govindarajan S, St Claire M, Shapiro M, Purcell RH. Identification of VP1/2A and 2C as virulence genes of hepatitis A virus and demonstration of genetic instability of 2C. Journal of Virology. 76: 8551-9. PMID 12163575 DOI: 10.1128/JVI.76.17.8551-8559.2002  0.127
1998 Raychaudhuri G, Govindarajan S, Shapiro M, Purcell RH, Emerson SU. Utilization of chimeras between human (HM-175) and simian (AGM-27) strains of hepatitis A virus to study the molecular basis of virulence. Journal of Virology. 72: 7467-75. PMID 9696843  0.127
1999 Funkhouser AW, Schultz DE, Lemon SM, Purcell RH, Emerson SU. Hepatitis A virus translation is rate-limiting for virus replication in MRC-5 cells. Virology. 254: 268-78. PMID 9986793 DOI: 10.1006/Viro.1998.9548  0.126
2013 Sanford BJ, Emerson SU, Purcell RH, Engle RE, Dryman BA, Cecere TE, Buechner-Maxwell V, Sponenberg DP, Meng XJ. Serological evidence for a hepatitis e virus-related agent in goats in the United States. Transboundary and Emerging Diseases. 60: 538-45. PMID 22909079 DOI: 10.1111/tbed.12001  0.126
1998 Robinson RA, Burgess WH, Emerson SU, Leibowitz RS, Sosnovtseva SA, Tsarev S, Purcell RH. Structural characterization of recombinant hepatitis E virus ORF2 proteins in baculovirus-infected insect cells. Protein Expression and Purification. 12: 75-84. PMID 9473460 DOI: 10.1006/prep.1997.0817  0.125
2011 Shukla P, Nguyen HT, Torian U, Engle RE, Faulk K, Dalton HR, Bendall RP, Keane FE, Purcell RH, Emerson SU. Cross-species infections of cultured cells by hepatitis E virus and discovery of an infectious virus-host recombinant. Proceedings of the National Academy of Sciences of the United States of America. 108: 2438-43. PMID 21262830 DOI: 10.1073/pnas.1018878108  0.125
1996 Cohen JI, Moskal T, Shapiro M, Purcell RH. Varicella in Chimpanzees. Journal of Medical Virology. 50: 289-92. PMID 8950684 DOI: 10.1002/(SICI)1096-9071(199612)50:4<289::AID-JMV2>3.0.CO;2-4  0.121
1999 Yanagi M, St Claire M, Emerson SU, Purcell RH, Bukh J. In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA clone. Proceedings of the National Academy of Sciences of the United States of America. 96: 2291-5. PMID 10051634 DOI: 10.1073/pnas.96.5.2291  0.121
2009 Russell RS, Kawaguchi K, Meunier JC, Takikawa S, Faulk K, Bukh J, Purcell RH, Emerson SU. Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles. Journal of Viral Hepatitis. 16: 621-32. PMID 19302336 DOI: 10.1111/j.1365-2893.2009.01111.x  0.121
2008 Graff J, Zhou YH, Torian U, Nguyen H, St Claire M, Yu C, Purcell RH, Emerson SU. Mutations within potential glycosylation sites in the capsid protein of hepatitis E virus prevent the formation of infectious virus particles. Journal of Virology. 82: 1185-94. PMID 18032496 DOI: 10.1128/JVI.01219-07  0.116
1996 Funkhouser AW, Raychaudhuri G, Purcell RH, Govindarajan S, Elkins R, Emerson SU. Progress toward the development of a genetically engineered attenuated hepatitis A virus vaccine. Journal of Virology. 70: 7948-57. PMID 8892918  0.116
2008 Vanwolleghem T, Bukh J, Meuleman P, Desombere I, Meunier JC, Alter H, Purcell RH, Leroux-Roels G. Polyclonal immunoglobulins from a chronic hepatitis C virus patient protect human liver-chimeric mice from infection with a homologous hepatitis C virus strain. Hepatology (Baltimore, Md.). 47: 1846-55. PMID 18452146 DOI: 10.1002/Hep.22244  0.116
1997 Meng XJ, Purcell RH, Halbur PG, Lehman JR, Webb DM, Tsareva TS, Haynes JS, Thacker BJ, Emerson SU. A novel virus in swine is closely related to the human hepatitis E virus. Proceedings of the National Academy of Sciences of the United States of America. 94: 9860-5. PMID 9275216 DOI: 10.1073/Pnas.94.18.9860  0.114
2007 Lai CJ, Goncalvez AP, Men R, Wernly C, Donau O, Engle RE, Purcell RH. Epitope determinants of a chimpanzee dengue virus type 4 (DENV-4)-neutralizing antibody and protection against DENV-4 challenge in mice and rhesus monkeys by passively transferred humanized antibody. Journal of Virology. 81: 12766-74. PMID 17881450 DOI: 10.1128/JVI.01420-07  0.113
2000 Hartmann G, Weeratna RD, Ballas ZK, Payette P, Blackwell S, Suparto I, Rasmussen WL, Waldschmidt M, Sajuthi D, Purcell RH, Davis HL, Krieg AM. Delineation of a CpG phosphorothioate oligodeoxynucleotide for activating primate immune responses in vitro and in vivo. Journal of Immunology (Baltimore, Md. : 1950). 164: 1617-24. PMID 10640783  0.113
2001 Emerson SU, Zhang M, Meng XJ, Nguyen H, St Claire M, Govindarajan S, Huang YK, Purcell RH. Recombinant hepatitis E virus genomes infectious for primates: importance of capping and discovery of a cis-reactive element. Proceedings of the National Academy of Sciences of the United States of America. 98: 15270-5. PMID 11742081 DOI: 10.1073/pnas.251555098  0.112
1998 Meng XJ, Halbur PG, Shapiro MS, Govindarajan S, Bruna JD, Mushahwar IK, Purcell RH, Emerson SU. Genetic and experimental evidence for cross-species infection by swine hepatitis E virus. Journal of Virology. 72: 9714-21. PMID 9811705 DOI: 10.1128/Jvi.72.12.9714-9721.1998  0.112
2010 Gottwein JM, Scheel TK, Callendret B, Li YP, Eccleston HB, Engle RE, Govindarajan S, Satterfield W, Purcell RH, Walker CM, Bukh J. Novel infectious cDNA clones of hepatitis C virus genotype 3a (strain S52) and 4a (strain ED43): genetic analyses and in vivo pathogenesis studies. Journal of Virology. 84: 5277-93. PMID 20200247 DOI: 10.1128/JVI.02667-09  0.112
2010 Farci P, Diaz G, Chen Z, Govindarajan S, Tice A, Agulto L, Pittaluga S, Boon D, Yu C, Engle RE, Haas M, Simon R, Purcell RH, Zamboni F. B cell gene signature with massive intrahepatic production of antibodies to hepatitis B core antigen in hepatitis B virus-associated acute liver failure. Proceedings of the National Academy of Sciences of the United States of America. 107: 8766-71. PMID 20421498 DOI: 10.1073/pnas.1003854107  0.112
2011 Xing L, Wang JC, Li TC, Yasutomi Y, Lara J, Khudyakov Y, Schofield D, Emerson SU, Purcell RH, Takeda N, Miyamura T, Cheng RH. Spatial configuration of hepatitis E virus antigenic domain. Journal of Virology. 85: 1117-24. PMID 21068233 DOI: 10.1128/Jvi.00657-10  0.111
2000 Schofield DJ, Glamann J, Emerson SU, Purcell RH. Identification by phage display and characterization of two neutralizing chimpanzee monoclonal antibodies to the hepatitis E virus capsid protein. Journal of Virology. 74: 5548-55. PMID 10823861 DOI: 10.1128/JVI.74.12.5548-5555.2000  0.111
2008 Goncalvez AP, Chien CH, Tubthong K, Gorshkova I, Roll C, Donau O, Schuck P, Yoksan S, Wang SD, Purcell RH, Lai CJ. Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo. Journal of Virology. 82: 7009-21. PMID 18480437 DOI: 10.1128/JVI.00291-08  0.111
1994 Bukh J, Purcell RH, Miller RH. Sequence analysis of the core gene of 14 hepatitis C virus genotypes. Proceedings of the National Academy of Sciences of the United States of America. 91: 8239-43. PMID 8058787  0.11
2013 Bukh J, Lanford RE, Purcell RH. Persistent human hepatitis B virus infection in cynomolgus monkeys: a novel animal model in the search for a cure? Hepatology (Baltimore, Md.). 58: 1533-6. PMID 23775673 DOI: 10.1002/Hep.26560  0.11
1993 Tsarev SA, Tsareva TS, Emerson SU, Kapikian AZ, Ticehurst J, London W, Purcell RH. ELISA for antibody to hepatitis E virus (HEV) based on complete open-reading frame-2 protein expressed in insect cells: identification of HEV infection in primates. The Journal of Infectious Diseases. 168: 369-78. PMID 8335973  0.109
1994 Sugata F, Chen HS, Kaneko S, Purcell RH, Miller RH. Analysis of the X gene promoter of woodchuck hepatitis virus. Virology. 205: 314-20. PMID 7975227 DOI: 10.1006/viro.1994.1647  0.106
2003 Emerson SU, Purcell RH. Hepatitis E virus. Reviews in Medical Virology. 13: 145-54. PMID 12740830 DOI: 10.1002/rmv.384  0.106
2000 Hu X, Margolis HS, Purcell RH, Ebert J, Robertson BH. Identification of hepatitis B virus indigenous to chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 97: 1661-4. PMID 10677515 DOI: 10.1073/Pnas.97.4.1661  0.106
2004 Wieland S, Thimme R, Purcell RH, Chisari FV. Genomic analysis of the host response to hepatitis B virus infection. Proceedings of the National Academy of Sciences of the United States of America. 101: 6669-74. PMID 15100412 DOI: 10.1073/pnas.0401771101  0.105
1991 Emerson SU, Tsarev SA, Purcell RH. Biological and molecular comparisons of human (HM-175) and simian (AGM-27) hepatitis A viruses. Journal of Hepatology. 13: S144-5. PMID 1668325  0.105
1997 Forns X, Bukh J, Purcell RH, Emerson SU. How Escherichia coli can bias the results of molecular cloning: preferential selection of defective genomes of hepatitis C virus during the cloning procedure. Proceedings of the National Academy of Sciences of the United States of America. 94: 13909-14. PMID 9391126 DOI: 10.1073/pnas.94.25.13909  0.105
1999 Forns X, Emerson SU, Tobin GJ, Mushahwar IK, Purcell RH, Bukh J. DNA immunization of mice and macaques with plasmids encoding hepatitis C virus envelope E2 protein expressed intracellularly and on the cell surface. Vaccine. 17: 1992-2002. PMID 10217599 DOI: 10.1016/S0264-410X(98)00448-4  0.105
2012 Li YP, Ramirez S, Gottwein JM, Scheel TK, Mikkelsen L, Purcell RH, Bukh J. Robust full-length hepatitis C virus genotype 2a and 2b infectious cultures using mutations identified by a systematic approach applicable to patient strains. Proceedings of the National Academy of Sciences of the United States of America. 109: E1101-10. PMID 22467829 DOI: 10.1073/pnas.1203829109  0.104
2006 Emerson SU, Nguyen H, Torian U, Purcell RH. ORF3 protein of hepatitis E virus is not required for replication, virion assembly, or infection of hepatoma cells in vitro. Journal of Virology. 80: 10457-64. PMID 16928762 DOI: 10.1128/JVI.00892-06  0.104
2001 Nam JH, Bukh J, Purcell RH, Emerson SU. High-level expression of hepatitis C virus (HCV) structural proteins by a chimeric HCV/BVDV genome propagated as a BVDV pseudotype. Journal of Virological Methods. 97: 113-23. PMID 11483222 DOI: 10.1016/S0166-0934(01)00339-1  0.104
1995 Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of the hepatitis C virus. Princess Takamatsu Symposia. 25: 75-91. PMID 8875612  0.103
2013 Chen Z, Sosnovtsev SV, Bok K, Parra GI, Makiya M, Agulto L, Green KY, Purcell RH. Development of Norwalk virus-specific monoclonal antibodies with therapeutic potential for the treatment of Norwalk virus gastroenteritis. Journal of Virology. 87: 9547-57. PMID 23785216 DOI: 10.1128/JVI.01376-13  0.103
2001 Purcell RH, Emerson SU. Animal models of hepatitis A and E. Ilar Journal / National Research Council, Institute of Laboratory Animal Resources. 42: 161-77. PMID 11406718  0.102
2002 Farci P, Strazzera R, Alter HJ, Farci S, Degioannis D, Coiana A, Peddis G, Usai F, Serra G, Chessa L, Diaz G, Balestrieri A, Purcell RH. Early changes in hepatitis C viral quasispecies during interferon therapy predict the therapeutic outcome. Proceedings of the National Academy of Sciences of the United States of America. 99: 3081-6. PMID 11880647 DOI: 10.1073/Pnas.052712599  0.101
1993 Bukh J, Purcell RH, Miller RH. At least 12 genotypes of hepatitis C virus predicted by sequence analysis of the putative E1 gene of isolates collected worldwide. Proceedings of the National Academy of Sciences of the United States of America. 90: 8234-8. PMID 8396266  0.101
2003 Sakai A, Claire MS, Faulk K, Govindarajan S, Emerson SU, Purcell RH, Bukh J. The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences. Proceedings of the National Academy of Sciences of the United States of America. 100: 11646-51. PMID 14504405 DOI: 10.1073/pnas.1834545100  0.1
2011 Leysath CE, Chen KH, Moayeri M, Crown D, Fattah R, Chen Z, Das SR, Purcell RH, Leppla SH. Mouse monoclonal antibodies to anthrax edema factor protect against infection. Infection and Immunity. 79: 4609-16. PMID 21911463 DOI: 10.1128/IAI.05314-11  0.1
2010 Bukh J, Meuleman P, Tellier R, Engle RE, Feinstone SM, Eder G, Satterfield WC, Govindarajan S, Krawczynski K, Miller RH, Leroux-Roels G, Purcell RH. Challenge pools of hepatitis C virus genotypes 1-6 prototype strains: replication fitness and pathogenicity in chimpanzees and human liver-chimeric mouse models. The Journal of Infectious Diseases. 201: 1381-9. PMID 20353362 DOI: 10.1086/651579  0.1
2011 Boon D, Mahar JE, Abente EJ, Kirkwood CD, Purcell RH, Kapikian AZ, Green KY, Bok K. Comparative evolution of GII.3 and GII.4 norovirus over a 31-year period. Journal of Virology. 85: 8656-66. PMID 21715504 DOI: 10.1128/JVI.00472-11  0.1
1998 Bukh J, Kim JP, Govindarajan S, Apgar CL, Foung SK, Wages J, Yun AJ, Shapiro M, Emerson SU, Purcell RH. Experimental infection of chimpanzees with hepatitis G virus and genetic analysis of the virus. The Journal of Infectious Diseases. 177: 855-62. PMID 9534956  0.099
2004 Goncalvez AP, Men R, Wernly C, Purcell RH, Lai CJ. Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 antibody that efficiently cross-neutralize dengue type 1 and type 2 viruses. Journal of Virology. 78: 12910-8. PMID 15542643 DOI: 10.1128/JVI.78.23.12910-12918.2004  0.099
2001 Zhang M, Emerson SU, Nguyen H, Engle RE, Govindarajan S, Gerin JL, Purcell RH. Immunogenicity and protective efficacy of a vaccine prepared from 53 kDa truncated hepatitis E virus capsid protein expressed in insect cells. Vaccine. 20: 853-7. PMID 11738749 DOI: 10.1016/S0264-410X(01)00399-1  0.099
1994 Emerson SU, Lewis M, Govindarajan S, Shapiro M, Moskal T, Purcell RH. In vivo transfection by hepatitis A virus synthetic RNA. Archives of Virology. Supplementum. 9: 205-9. PMID 8032252  0.098
1992 Emerson SU, Huang YK, McRill C, Lewis M, Purcell RH. Mutations in both the 2B and 2C genes of hepatitis A virus are involved in adaptation to growth in cell culture. Journal of Virology. 66: 650-4. PMID 1309907  0.098
2008 Russell RS, Meunier JC, Takikawa S, Faulk K, Engle RE, Bukh J, Purcell RH, Emerson SU. Advantages of a single-cycle production assay to study cell culture-adaptive mutations of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 105: 4370-5. PMID 18334634 DOI: 10.1073/pnas.0800422105  0.098
2007 Shata MT, Barrett A, Shire NJ, Abdelwahab SF, Sobhy M, Daef E, El-Kamary SS, Hashem M, Engle RE, Purcell RH, Emerson SU, Strickland GT, Sherman KE. Characterization of hepatitis E-specific cell-mediated immune response using IFN-gamma ELISPOT assay. Journal of Immunological Methods. 328: 152-61. PMID 17905301 DOI: 10.1016/J.Jim.2007.08.014  0.097
1990 Collins PL, Purcell RH, London WT, Lawrence LA, Chanock RM, Murphy BR. Evaluation in chimpanzees of vaccinia virus recombinants that express the surface glycoproteins of human respiratory syncytial virus. Vaccine. 8: 164-8. PMID 2336876 DOI: 10.1016/0264-410X(90)90141-8  0.097
1992 Chen HS, Kew MC, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH. The precore gene of the woodchuck hepatitis virus genome is not essential for viral replication in the natural host. Journal of Virology. 66: 5682-4. PMID 1501300  0.096
1991 Ogata N, Alter HJ, Miller RH, Purcell RH. Nucleotide sequence and mutation rate of the H strain of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 88: 3392-6. PMID 1849654 DOI: 10.1073/Pnas.88.8.3392  0.096
2007 Goncalvez AP, Engle RE, St Claire M, Purcell RH, Lai CJ. Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention. Proceedings of the National Academy of Sciences of the United States of America. 104: 9422-7. PMID 17517625 DOI: 10.1073/pnas.0703498104  0.095
1992 Shimizu YK, Iwamoto A, Hijikata M, Purcell RH, Yoshikura H. Evidence for in vitro replication of hepatitis C virus genome in a human T-cell line. Proceedings of the National Academy of Sciences of the United States of America. 89: 5477-81. PMID 1319062  0.095
1998 Yanagi M, St Claire M, Shapiro M, Emerson SU, Purcell RH, Bukh J. Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo. Virology. 244: 161-72. PMID 9581788 DOI: 10.1006/viro.1998.9092  0.095
1998 Meng XJ, Halbur PG, Haynes JS, Tsareva TS, Bruna JD, Royer RL, Purcell RH, Emerson SU. Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV. Archives of Virology. 143: 1405-15. PMID 9722883 DOI: 10.1007/S007050050384  0.095
2012 Farci P, Wollenberg K, Diaz G, Engle RE, Lai ME, Klenerman P, Purcell RH, Pybus OG, Alter HJ. Profibrogenic chemokines and viral evolution predict rapid progression of hepatitis C to cirrhosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 14562-7. PMID 22829669 DOI: 10.1073/Pnas.1210592109  0.094
2000 Romeo R, Hegerich P, Emerson SU, Colombo M, Purcell RH, Bukh J. High prevalence of TT virus (TTV) in naive chimpanzees and in hepatitis C virus-infected humans: frequent mixed infections and identification of new TTV genotypes in chimpanzees. The Journal of General Virology. 81: 1001-7. PMID 10725426 DOI: 10.1099/0022-1317-81-4-1001  0.094
2000 Forns X, Thimme R, Govindarajan S, Emerson SU, Purcell RH, Chisari FV, Bukh J. Hepatitis C virus lacking the hypervariable region 1 of the second envelope protein is infectious and causes acute resolving or persistent infection in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 97: 13318-23. PMID 11078521 DOI: 10.1073/Pnas.230453597  0.094
2004 Zhou YH, Purcell RH, Emerson SU. An ELISA for putative neutralizing antibodies to hepatitis E virus detects antibodies to genotypes 1, 2, 3, and 4. Vaccine. 22: 2578-85. PMID 15193383 DOI: 10.1016/j.vaccine.2003.12.017  0.093
2012 Li YP, Ramirez S, Jensen SB, Purcell RH, Gottwein JM, Bukh J. Highly efficient full-length hepatitis C virus genotype 1 (strain TN) infectious culture system. Proceedings of the National Academy of Sciences of the United States of America. 109: 19757-62. PMID 23151512 DOI: 10.1073/pnas.1218260109  0.093
2010 Emerson SU, Nguyen HT, Torian U, Burke D, Engle R, Purcell RH. Release of genotype 1 hepatitis E virus from cultured hepatoma and polarized intestinal cells depends on open reading frame 3 protein and requires an intact PXXP motif. Journal of Virology. 84: 9059-69. PMID 20610720 DOI: 10.1128/JVI.00593-10  0.092
2005 Murray JM, Wieland SF, Purcell RH, Chisari FV. Dynamics of hepatitis B virus clearance in chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 102: 17780-5. PMID 16306261 DOI: 10.1073/Pnas.0508913102  0.092
2004 Goncalvez AP, Purcell RH, Lai CJ. Epitope determinants of a chimpanzee Fab antibody that efficiently cross-neutralizes dengue type 1 and type 2 viruses map to inside and in close proximity to fusion loop of the dengue type 2 virus envelope glycoprotein. Journal of Virology. 78: 12919-28. PMID 15542644 DOI: 10.1128/JVI.78.23.12919-12928.2004  0.091
2011 Meuleman P, Bukh J, Verhoye L, Farhoudi A, Vanwolleghem T, Wang RY, Desombere I, Alter H, Purcell RH, Leroux-Roels G. In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus. Hepatology (Baltimore, Md.). 53: 755-62. PMID 21319203 DOI: 10.1002/Hep.24171  0.091
2013 Purcell RH, Engle RE, Govindarajan S, Herbert R, St Claire M, Elkins WR, Cook A, Shaver C, Beauregard M, Swerczek J, Emerson SU. Pathobiology of hepatitis E: lessons learned from primate models. Emerging Microbes & Infections. 2: e9. PMID 26038457 DOI: 10.1038/emi.2013.9  0.091
2006 Takikawa S, Engle RE, Emerson SU, Purcell RH, St Claire M, Bukh J. Functional analyses of GB virus B p13 protein: development of a recombinant GB virus B hepatitis virus with a p7 protein. Proceedings of the National Academy of Sciences of the United States of America. 103: 3345-50. PMID 16492760 DOI: 10.1073/pnas.0511297103  0.09
1999 Forns X, Hegerich P, Darnell A, Emerson SU, Purcell RH, Bukh J. High prevalence of TT virus (TTV) infection in patients on maintenance hemodialysis: frequent mixed infections with different genotypes and lack of evidence of associated liver disease. Journal of Medical Virology. 59: 313-7. PMID 10502262 DOI: 10.1002/(SICI)1096-9071(199911)59:3<313::AID-JMV9>3.0.CO;2-B  0.09
2011 Bok K, Parra GI, Mitra T, Abente E, Shaver CK, Boon D, Engle R, Yu C, Kapikian AZ, Sosnovtsev SV, Purcell RH, Green KY. Chimpanzees as an animal model for human norovirus infection and vaccine development. Proceedings of the National Academy of Sciences of the United States of America. 108: 325-30. PMID 21173246 DOI: 10.1073/pnas.1014577107  0.09
1991 Purcell RH, Miller RH. The nature of genetic variation among viruses. Journal of Hepatology. 13: S2-5. PMID 1822512 DOI: 10.1016/0168-8278(91)90014-3  0.089
1992 Emerson SU, Lewis M, Govindarajan S, Shapiro M, Moskal T, Purcell RH. cDNA clone of hepatitis A virus encoding a virulent virus: induction of viral hepatitis by direct nucleic acid transfection of marmosets. Journal of Virology. 66: 6649-54. PMID 1328684  0.089
1996 Tellier R, Bukh J, Emerson SU, Purcell RH. Amplification of the full-length hepatitis A virus genome by long reverse transcription-PCR and transcription of infectious RNA directly from the amplicon. Proceedings of the National Academy of Sciences of the United States of America. 93: 4370-3. PMID 8633073  0.088
2011 Callendret B, Bukh J, Eccleston HB, Heksch R, Hasselschwert DL, Purcell RH, Hughes AL, Walker CM. Transmission of clonal hepatitis C virus genomes reveals the dominant but transitory role of CD8⁺ T cells in early viral evolution. Journal of Virology. 85: 11833-45. PMID 21900166 DOI: 10.1128/Jvi.02654-10  0.088
2009 Chen Z, Moayeri M, Zhao H, Crown D, Leppla SH, Purcell RH. Potent neutralization of anthrax edema toxin by a humanized monoclonal antibody that competes with calmodulin for edema factor binding. Proceedings of the National Academy of Sciences of the United States of America. 106: 13487-92. PMID 19651602 DOI: 10.1073/pnas.0906581106  0.087
1999 McCluskie MJ, Brazolot Millan CL, Gramzinski RA, Robinson HL, Santoro JC, Fuller JT, Widera G, Haynes JR, Purcell RH, Davis HL. Route and method of delivery of DNA vaccine influence immune responses in mice and non-human primates. Molecular Medicine (Cambridge, Mass.). 5: 287-300. PMID 10390545  0.087
2002 Christensen PB, Engle RE, Jacobsen SE, Krarup HB, Georgsen J, Purcell RH. High prevalence of hepatitis E antibodies among Danish prisoners and drug users. Journal of Medical Virology. 66: 49-55. PMID 11748658 DOI: 10.1002/jmv.2110  0.087
1993 Kew MC, Miller RH, Chen HS, Tennant BC, Purcell RH. Mutant woodchuck hepatitis virus genomes from virions resemble rearranged hepadnaviral integrants in hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 90: 10211-5. PMID 8234278  0.087
2006 Emerson SU, Clemente-Casares P, Moiduddin N, Arankalle VA, Torian U, Purcell RH. Putative neutralization epitopes and broad cross-genotype neutralization of Hepatitis E virus confirmed by a quantitative cell-culture assay. The Journal of General Virology. 87: 697-704. PMID 16476993 DOI: 10.1099/vir.0.81545-0  0.086
2015 Sarkar S, Rivera EM, Engle RE, Nguyen HT, Schechterly CA, Alter HJ, Liang TJ, Purcell RH, Hoofnagle JH, Ghany MG. An Epidemiologic Investigation Of A Case Of Acute Hepatitis E. Journal of Clinical Microbiology. PMID 26338861 DOI: 10.1128/Jcm.01189-15  0.086
2013 Shimizu YK, Hijikata M, Oshima M, Shimizu K, Alter HJ, Purcell RH, Yoshikura H, Hotta H. Isolation of human monoclonal antibodies to the envelope e2 protein of hepatitis C virus and their characterization. Plos One. 8: e55874. PMID 23409074 DOI: 10.1371/Journal.Pone.0055874  0.086
1989 Cohen JI, Rosenblum B, Feinstone SM, Ticehurst J, Purcell RH. Attenuation and cell culture adaptation of hepatitis A virus (HAV): a genetic analysis with HAV cDNA. Journal of Virology. 63: 5364-70. PMID 2555561  0.086
2001 Bukh J, Apgar CL, Govindarajan S, Purcell RH. Host range studies of GB virus-B hepatitis agent, the closest relative of hepatitis C virus, in New World monkeys and chimpanzees. Journal of Medical Virology. 65: 694-7. PMID 11745933 DOI: 10.1002/jmv.2092  0.085
1994 Tappero G, Natoli G, Anfossi G, Rosina F, Negro F, Smedile A, Bonino F, Angeli A, Purcell RH, Rizzetto M. Expression of the c-myc protooncogene product in cells infected with the hepatitis delta virus. Hepatology (Baltimore, Md.). 20: 1109-14. PMID 7523269  0.085
1999 Kabrane-Lazizi Y, Meng XJ, Purcell RH, Emerson SU. Evidence that the genomic RNA of hepatitis E virus is capped. Journal of Virology. 73: 8848-50. PMID 10482642 DOI: 10.1128/Jvi.73.10.8848-8850.1999  0.085
2006 Stoszek SK, Abdel-Hamid M, Saleh DA, El Kafrawy S, Narooz S, Hawash Y, Shebl FM, El Daly M, Said A, Kassem E, Mikhail N, Engle RE, Sayed M, Sharaf S, Fix AD, ... ... Purcell RH, et al. High prevalence of hepatitis E antibodies in pregnant Egyptian women. Transactions of the Royal Society of Tropical Medicine and Hygiene. 100: 95-101. PMID 16257426 DOI: 10.1016/J.Trstmh.2004.12.005  0.085
2011 Mensa L, Crespo G, Gastinger MJ, Kabat J, Pérez-del-Pulgar S, Miquel R, Emerson SU, Purcell RH, Forns X. Hepatitis C virus receptors claudin-1 and occludin after liver transplantation and influence on early viral kinetics. Hepatology (Baltimore, Md.). 53: 1436-45. PMID 21294144 DOI: 10.1002/hep.24110  0.084
2002 Ma X, Forns X, Gutierrez R, Mushahwar IK, Wu T, Payette PJ, Bukh J, Purcell RH, Davis HL. DNA-based vaccination against hepatitis C virus (HCV): effect of expressing different forms of HCV E2 protein and use of CpG-optimized vectors in mice. Vaccine. 20: 3263-71. PMID 12213395 DOI: 10.1016/S0264-410X(02)00304-3  0.084
1994 Purcell RH. Hepatitis viruses: changing patterns of human disease. Proceedings of the National Academy of Sciences of the United States of America. 91: 2401-6. PMID 8146130  0.084
2000 Farci P, Purcell RH. Clinical significance of hepatitis C virus genotypes and quasispecies. Seminars in Liver Disease. 20: 103-26. PMID 10895435  0.084
1990 Miller RH, Purcell RH. Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroups. Proceedings of the National Academy of Sciences of the United States of America. 87: 2057-61. PMID 2156259  0.084
1990 Miller RH, Girones R, Cote PJ, Hornbuckle WE, Chestnut T, Baldwin BH, Korba BE, Tennant BC, Gerin JL, Purcell RH. Evidence against a requisite role for defective virus in the establishment of persistent hepadnavirus infections. Proceedings of the National Academy of Sciences of the United States of America. 87: 9329-32. PMID 2251274 DOI: 10.1073/Pnas.87.23.9329  0.083
1997 Forns X, Tan D, Alter HJ, Purcell RH, Bukh J. Evaluation of commercially available and in-house reverse transcription-PCR assays for detection of hepatitis G virus or GB virus C. Journal of Clinical Microbiology. 35: 2698-702. PMID 9316941 DOI: 10.1128/jcm.35.10.2698-2702.1997  0.083
2007 Yu C, Zimmerman C, Stone R, Engle RE, Elkins W, Nardone GA, Emerson SU, Purcell RH. Using improved technology for filter paper-based blood collection to survey wild Sika deer for antibodies to hepatitis E virus. Journal of Virological Methods. 142: 143-50. PMID 17336401 DOI: 10.1016/j.jviromet.2007.01.016  0.082
2004 Wieland SF, Spangenberg HC, Thimme R, Purcell RH, Chisari FV. Expansion and contraction of the hepatitis B virus transcriptional template in infected chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 101: 2129-34. PMID 14764900 DOI: 10.1073/Pnas.0308478100  0.082
2009 Kuniholm MH, Purcell RH, McQuillan GM, Engle RE, Wasley A, Nelson KE. Epidemiology of hepatitis E virus in the United States: results from the Third National Health and Nutrition Examination Survey, 1988-1994. The Journal of Infectious Diseases. 200: 48-56. PMID 19473098 DOI: 10.1086/599319  0.081
2015 Kmush BL, Labrique A, Li W, Klein SL, Schulze K, Shaikh S, Ali H, Engle RE, Wu L, Purcell RH, Mehra S, Christian P, West K, Nelson K. The Association of Cytokines and Micronutrients with Hepatitis E Virus Infection during Pregnancy and the Postpartum Period in Rural Bangladesh. The American Journal of Tropical Medicine and Hygiene. PMID 26621563 DOI: 10.4269/Ajtmh.15-0238  0.081
1997 Morris TS, Frormann S, Shechosky S, Lowe C, Lall MS, Gauss-Müller V, Purcell RH, Emerson SU, Vederas JC, Malcolm BA. In vitro and ex vivo inhibition of hepatitis A virus 3C proteinase by a peptidyl monofluoromethyl ketone. Bioorganic & Medicinal Chemistry. 5: 797-807. PMID 9208091 DOI: 10.1016/S0968-0896(97)88649-X  0.081
1999 Arankalle VA, Paranjape S, Emerson SU, Purcell RH, Walimbe AM. Phylogenetic analysis of hepatitis E virus isolates from India (1976-1993). The Journal of General Virology. 80: 1691-700. PMID 10423137  0.081
2006 Stoszek SK, Engle RE, Abdel-Hamid M, Mikhail N, Abdel-Aziz F, Medhat A, Fix AD, Emerson SU, Purcell RH, Strickland GT. Hepatitis E antibody seroconversion without disease in highly endemic rural Egyptian communities. Transactions of the Royal Society of Tropical Medicine and Hygiene. 100: 89-94. PMID 16257427 DOI: 10.1016/j.trstmh.2005.05.019  0.08
2002 Schofield DJ, Satterfield W, Emerson SU, Purcell RH. Four chimpanzee monoclonal antibodies isolated by phage display neutralize hepatitis a virus. Virology. 292: 127-36. PMID 11878915 DOI: 10.1006/viro.2001.1252  0.08
2001 Allander T, Emerson SU, Engle RE, Purcell RH, Bukh J. A virus discovery method incorporating DNase treatment and its application to the identification of two bovine parvovirus species. Proceedings of the National Academy of Sciences of the United States of America. 98: 11609-14. PMID 11562506 DOI: 10.1073/pnas.211424698  0.08
2001 Halbur PG, Kasorndorkbua C, Gilbert C, Guenette D, Potters MB, Purcell RH, Emerson SU, Toth TE, Meng XJ. Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human. Journal of Clinical Microbiology. 39: 918-23. PMID 11230404 DOI: 10.1128/Jcm.39.3.918-923.2001  0.08
2013 Wu W, Chen Z, Cheng N, Watts NR, Stahl SJ, Farci P, Purcell RH, Wingfield PT, Steven AC. Specificity of an anti-capsid antibody associated with Hepatitis B Virus-related acute liver failure. Journal of Structural Biology. 181: 53-60. PMID 23079477 DOI: 10.1016/J.Jsb.2012.10.004  0.08
2009 Chen Z, Moayeri M, Crown D, Emerson S, Gorshkova I, Schuck P, Leppla SH, Purcell RH. Novel chimpanzee/human monoclonal antibodies that neutralize anthrax lethal factor, and evidence for possible synergy with anti-protective antigen antibody. Infection and Immunity. 77: 3902-8. PMID 19528217 DOI: 10.1128/IAI.00200-09  0.08
2000 Farci P, Shimoda A, Coiana A, Diaz G, Peddis G, Melpolder JC, Strazzera A, Chien DY, Munoz SJ, Balestrieri A, Purcell RH, Alter HJ. The outcome of acute hepatitis C predicted by the evolution of the viral quasispecies. Science (New York, N.Y.). 288: 339-44. PMID 10764648 DOI: 10.1126/Science.288.5464.339  0.08
2010 Takikawa S, Engle RE, Faulk KN, Emerson SU, Purcell RH, Bukh J. Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins. The Journal of General Virology. 91: 727-33. PMID 19906942 DOI: 10.1099/vir.0.015750-0  0.079
2001 Bukh J, Forns X, Emerson SU, Purcell RH. Studies of hepatitis C virus in chimpanzees and their importance for vaccine development. Intervirology. 44: 132-42. PMID 11509874 DOI: 10.1159/000050040  0.079
1993 Chen HS, Kaneko S, Girones R, Anderson RW, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH, Miller RH. The woodchuck hepatitis virus X gene is important for establishment of virus infection in woodchucks. Journal of Virology. 67: 1218-26. PMID 8437213  0.079
1999 Yanagi M, Purcell RH, Emerson SU, Bukh J. Hepatitis C virus: an infectious molecular clone of a second major genotype (2a) and lack of viability of intertypic 1a and 2a chimeras. Virology. 262: 250-63. PMID 10489358 DOI: 10.1006/viro.1999.9889  0.078
1997 Ogata N, Zanetti AR, Yu M, Miller RH, Purcell RH. Infectivity and pathogenicity in chimpanzees of a surface gene mutant of hepatitis B virus that emerged in a vaccinated infant. The Journal of Infectious Diseases. 175: 511-23. PMID 9041321  0.078
2007 Easterbrook JD, Kaplan JB, Vanasco NB, Reeves WK, Purcell RH, Kosoy MY, Glass GE, Watson J, Klein SL. A survey of zoonotic pathogens carried by Norway rats in Baltimore, Maryland, USA. Epidemiology and Infection. 135: 1192-9. PMID 17224086 DOI: 10.1017/S0950268806007746  0.078
1995 Bukh J, Miller RH, Purcell RH. Genetic heterogeneity of hepatitis C virus: quasispecies and genotypes. Seminars in Liver Disease. 15: 41-63. PMID 7597443 DOI: 10.1055/s-2007-1007262  0.077
1997 Thomas DL, Yarbough PO, Vlahov D, Tsarev SA, Nelson KE, Saah AJ, Purcell RH. Seroreactivity to hepatitis E virus in areas where the disease is not endemic. Journal of Clinical Microbiology. 35: 1244-7. PMID 9114415 DOI: 10.1128/Jcm.35.5.1244-1247.1997  0.077
2011 Chen Z, Schneerson R, Lovchik J, Lyons CR, Zhao H, Dai Z, Kubler-Kielb J, Leppla SH, Purcell RH. Pre- and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule. Proceedings of the National Academy of Sciences of the United States of America. 108: 739-44. PMID 21187383 DOI: 10.1073/pnas.1017677108  0.077
1996 Yu M, Miller RH, Emerson S, Purcell RH. A hydrophobic heptad repeat of the core protein of woodchuck hepatitis virus is required for capsid assembly. Journal of Virology. 70: 7085-91. PMID 8794354  0.077
2004 Men R, Yamashiro T, Goncalvez AP, Wernly C, Schofield DJ, Emerson SU, Purcell RH, Lai CJ. Identification of chimpanzee Fab fragments by repertoire cloning and production of a full-length humanized immunoglobulin G1 antibody that is highly efficient for neutralization of dengue type 4 virus. Journal of Virology. 78: 4665-74. PMID 15078949 DOI: 10.1128/JVI.78.9.4665-4674.2004  0.077
1995 Bukh J, Miller RH, Purcell RH. Biology and genetic heterogeneity of hepatitis C virus. Clinical and Experimental Rheumatology. 13: S3-7. PMID 8730468  0.077
1990 Dienes HP, Purcell RH, Popper H, Ponzetto A. The significance of infections with two types of viral hepatitis demonstrated by histologic features in chimpanzees. Journal of Hepatology. 10: 77-84. PMID 2106549 DOI: 10.1016/0168-8278(90)90076-4  0.077
1996 Tellier R, Bukh J, Emerson SU, Miller RH, Purcell RH. Long PCR and its application to hepatitis viruses: amplification of hepatitis A, hepatitis B, and hepatitis C virus genomes. Journal of Clinical Microbiology. 34: 3085-91. PMID 8940452  0.076
2005 Schofield DJ, Bartosch B, Shimizu YK, Allander T, Alter HJ, Emerson SU, Cosset FL, Purcell RH. Human monoclonal antibodies that react with the E2 glycoprotein of hepatitis C virus and possess neutralizing activity. Hepatology (Baltimore, Md.). 42: 1055-62. PMID 16250048 DOI: 10.1002/Hep.20906  0.076
2008 Bukh J, Thimme R, Meunier JC, Faulk K, Spangenberg HC, Chang KM, Satterfield W, Chisari FV, Purcell RH. Previously infected chimpanzees are not consistently protected against reinfection or persistent infection after reexposure to the identical hepatitis C virus strain. Journal of Virology. 82: 8183-95. PMID 18550671 DOI: 10.1128/Jvi.00142-08  0.076
1996 Farci P, Shimoda A, Wong D, Cabezon T, De Gioannis D, Strazzera A, Shimizu Y, Shapiro M, Alter HJ, Purcell RH. Prevention of hepatitis C virus infection in chimpanzees by hyperimmune serum against the hypervariable region 1 of the envelope 2 protein. Proceedings of the National Academy of Sciences of the United States of America. 93: 15394-9. PMID 8986822 DOI: 10.1073/Pnas.93.26.15394  0.075
1994 Farci P, Alter HJ, Wong DC, Miller RH, Govindarajan S, Engle R, Shapiro M, Purcell RH. Prevention of hepatitis C virus infection in chimpanzees after antibody-mediated in vitro neutralization. Proceedings of the National Academy of Sciences of the United States of America. 91: 7792-6. PMID 7519785 DOI: 10.1073/Pnas.91.16.7792  0.075
2013 Chen Z, Fischer ER, Kouiavskaia D, Hansen BT, Ludtke SJ, Bidzhieva B, Makiya M, Agulto L, Purcell RH, Chumakov K. Cross-neutralizing human anti-poliovirus antibodies bind the recognition site for cellular receptor. Proceedings of the National Academy of Sciences of the United States of America. 110: 20242-7. PMID 24277851 DOI: 10.1073/pnas.1320041110  0.075
2009 Tang S, Moayeri M, Chen Z, Harma H, Zhao J, Hu H, Purcell RH, Leppla SH, Hewlett IK. Detection of anthrax toxin by an ultrasensitive immunoassay using europium nanoparticles. Clinical and Vaccine Immunology : Cvi. 16: 408-13. PMID 19129473 DOI: 10.1128/CVI.00412-08  0.074
2008 Meunier JC, Russell RS, Engle RE, Faulk KN, Purcell RH, Emerson SU. Apolipoprotein c1 association with hepatitis C virus. Journal of Virology. 82: 9647-56. PMID 18667498 DOI: 10.1128/JVI.00914-08  0.074
1999 Ogata N, Cote PJ, Zanetti AR, Miller RH, Shapiro M, Gerin J, Purcell RH. Licensed recombinant hepatitis B vaccines protect chimpanzees against infection with the prototype surface gene mutant of hepatitis B virus. Hepatology (Baltimore, Md.). 30: 779-86. PMID 10462386 DOI: 10.1002/hep.510300309  0.074
1994 Funkhouser AW, Purcell RH, D'Hondt E, Emerson SU. Attenuated hepatitis A virus: genetic determinants of adaptation to growth in MRC-5 cells. Journal of Virology. 68: 148-57. PMID 8254724  0.073
2002 Engle RE, Yu C, Emerson SU, Meng XJ, Purcell RH. Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay. Journal of Clinical Microbiology. 40: 4576-80. PMID 12454155 DOI: 10.1128/JCM.40.12.4576-4580.2002  0.073
2008 Bukh J, Engle RE, Govindarajan S, Purcell RH. Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived. Journal of Medical Virology. 80: 87-94. PMID 18041000 DOI: 10.1002/jmv.21013  0.073
2005 Meunier JC, Engle RE, Faulk K, Zhao M, Bartosch B, Alter H, Emerson SU, Cosset FL, Purcell RH, Bukh J. Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1. Proceedings of the National Academy of Sciences of the United States of America. 102: 4560-5. PMID 15767578 DOI: 10.1073/Pnas.0501275102  0.073
2008 Purcell RH, Emerson SU. Hepatitis E: an emerging awareness of an old disease. Journal of Hepatology. 48: 494-503. PMID 18192058 DOI: 10.1016/j.jhep.2007.12.008  0.073
2003 Tellier R, Bukh J, Emerson SU, Purcell RH. Long PCR amplification of large fragments of viral genomes: a technical overview. Methods in Molecular Biology (Clifton, N.J.). 226: 167-72. PMID 12958497 DOI: 10.1385/1-59259-384-4:167  0.073
1998 Pina S, Jofre J, Emerson SU, Purcell RH, Girones R. Characterization of a strain of infectious hepatitis E virus isolated from sewage in an area where hepatitis E is not endemic. Applied and Environmental Microbiology. 64: 4485-8. PMID 9797311  0.073
1999 Forns X, Purcell RH, Bukh J. Quasispecies in viral persistence and pathogenesis of hepatitis C virus. Trends in Microbiology. 7: 402-10. PMID 10498948 DOI: 10.1016/S0966-842X(99)01590-5  0.073
1998 Ghabrah TM, Tsarev S, Yarbough PO, Emerson SU, Strickland GT, Purcell RH. Comparison of tests for antibody to hepatitis E virus. Journal of Medical Virology. 55: 134-7. PMID 9598934 DOI: 10.1002/(SICI)1096-9071(199806)55:2<134::AID-JMV9>3.0.CO;2-3  0.072
2008 Meunier JC, Russell RS, Goossens V, Priem S, Walter H, Depla E, Union A, Faulk KN, Bukh J, Emerson SU, Purcell RH. Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus. Journal of Virology. 82: 966-73. PMID 17977972 DOI: 10.1128/JVI.01872-07  0.072
1997 Villano SA, Nelson KE, Vlahov D, Purcell RH, Saah AJ, Thomas DL. Hepatitis A among homosexual men and injection drug users: more evidence for vaccination. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 25: 726-8. PMID 9314468 DOI: 10.1086/513757  0.072
1994 Shimizu YK, Hijikata M, Iwamoto A, Alter HJ, Purcell RH, Yoshikura H. Neutralizing antibodies against hepatitis C virus and the emergence of neutralization escape mutant viruses. Journal of Virology. 68: 1494-500. PMID 8107212 DOI: 10.1128/jvi.68.3.1494-1500.1994  0.072
2006 Meky FA, Stoszek SK, Abdel-Hamid M, Selim S, Abdel-Wahab A, Mikhail N, El-Kafrawy S, El-Daly M, Abdel-Aziz F, Sharaf S, Mohamed MK, Engle RE, Emerson SU, Purcell RH, Fix AD, et al. Active surveillance for acute viral hepatitis in rural villages in the Nile Delta. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 42: 628-33. PMID 16447107 DOI: 10.1086/500133  0.072
1994 Tsarev SA, Tsareva TS, Emerson SU, Govindarajan S, Shapiro M, Gerin JL, Purcell RH. Successful passive and active immunization of cynomolgus monkeys against hepatitis E. Proceedings of the National Academy of Sciences of the United States of America. 91: 10198-202. PMID 7937861  0.072
1993 Tsarev SA, Emerson SU, Tsareva TS, Yarbough PO, Lewis M, Govindarajan S, Reyes GR, Shapiro M, Purcell RH. Variation in course of hepatitis E in experimentally infected cynomolgus monkeys. The Journal of Infectious Diseases. 167: 1302-6. PMID 8501318  0.071
1992 Negro F, Pacchioni D, Shimizu Y, Miller RH, Bussolati G, Purcell RH, Bonino F. Detection of intrahepatic replication of hepatitis C virus RNA by in situ hybridization and comparison with histopathology. Proceedings of the National Academy of Sciences of the United States of America. 89: 2247-51. PMID 1312716  0.071
2003 Bartosch B, Bukh J, Meunier JC, Granier C, Engle RE, Blackwelder WC, Emerson SU, Cosset FL, Purcell RH. In vitro assay for neutralizing antibody to hepatitis C virus: evidence for broadly conserved neutralization epitopes. Proceedings of the National Academy of Sciences of the United States of America. 100: 14199-204. PMID 14617769 DOI: 10.1073/pnas.2335981100  0.071
1992 Emerson SU, Huang YK, McRill C, Lewis M, Shapiro M, London WT, Purcell RH. Molecular basis of virulence and growth of hepatitis A virus in cell culture. Vaccine. 10: S36-9. PMID 1335656  0.07
1998 Shimizu YK, Igarashi H, Kiyohara T, Shapiro M, Wong DC, Purcell RH, Yoshikura H. Infection of a chimpanzee with hepatitis C virus grown in cell culture. The Journal of General Virology. 79: 1383-6. PMID 9634078  0.07
2011 Purcell RH, Engle RE, Rood MP, Kabrane-Lazizi Y, Nguyen HT, Govindarajan S, St Claire M, Emerson SU. Hepatitis E virus in rats, Los Angeles, California, USA. Emerging Infectious Diseases. 17: 2216-22. PMID 22172320 DOI: 10.3201/eid1712.110482  0.07
1996 Yanagi M, Bukh J, Emerson SU, Purcell RH. Contamination of commercially available fetal bovine sera with bovine viral diarrhea virus genomes: implications for the study of hepatitis C virus in cell cultures. The Journal of Infectious Diseases. 174: 1324-7. PMID 8940226  0.07
1989 Olmsted RA, Hirsch VM, Purcell RH, Johnson PR. Nucleotide sequence analysis of feline immunodeficiency virus: genome organization and relationship to other lentiviruses. Proceedings of the National Academy of Sciences of the United States of America. 86: 8088-92. PMID 2813380  0.07
1993 Ogata N, Miller RH, Ishak KG, Purcell RH. The complete nucleotide sequence of a pre-core mutant of hepatitis B virus implicated in fulminant hepatitis and its biological characterization in chimpanzees. Virology. 194: 263-76. PMID 8480422 DOI: 10.1006/viro.1993.1257  0.07
1996 Emerson SU, Tsarev SA, Govindarajan S, Shapiro M, Purcell RH. A simian strain of hepatitis A virus, AGM-27, functions as an attenuated vaccine for chimpanzees. The Journal of Infectious Diseases. 173: 592-7. PMID 8627022  0.07
2007 Sakai A, Takikawa S, Thimme R, Meunier JC, Spangenberg HC, Govindarajan S, Farci P, Emerson SU, Chisari FV, Purcell RH, Bukh J. In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells. Journal of Virology. 81: 7208-19. PMID 17409145 DOI: 10.1128/Jvi.01774-06  0.07
2001 Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B. 1975. Reviews in Medical Virology. 11: 3-8; discussion 8-9. PMID 11241798 DOI: 10.1002/rmv.304  0.069
1993 Ogata N, Ostberg L, Ehrlich PH, Wong DC, Miller RH, Purcell RH. Markedly prolonged incubation period of hepatitis B in a chimpanzee passively immunized with a human monoclonal antibody to the a determinant of hepatitis B surface antigen. Proceedings of the National Academy of Sciences of the United States of America. 90: 3014-8. PMID 8464917  0.069
1997 Yanagi M, Purcell RH, Emerson SU, Bukh J. Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzee. Proceedings of the National Academy of Sciences of the United States of America. 94: 8738-43. PMID 9238047  0.068
2002 Thimme R, Bukh J, Spangenberg HC, Wieland S, Pemberton J, Steiger C, Govindarajan S, Purcell RH, Chisari FV. Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease. Proceedings of the National Academy of Sciences of the United States of America. 99: 15661-8. PMID 12441397 DOI: 10.1073/Pnas.202608299  0.068
1989 Korba BE, Cote PJ, Shapiro M, Purcell RH, Gerin JL. In vitro production of infectious woodchuck hepatitis virus by lipopolysaccharide-stimulated peripheral blood lymphocytes. The Journal of Infectious Diseases. 160: 572-6. PMID 2794556 DOI: 10.1093/Infdis/160.4.572  0.067
2001 Zhang M, Purcell RH, Emerson SU. Identification of the 5' terminal sequence of the SAR-55 and MEX-14 strains of hepatitis E virus and confirmation that the genome is capped. Journal of Medical Virology. 65: 293-5. PMID 11536235 DOI: 10.1002/jmv.2032  0.067
2013 Dickens C, Kew MC, Purcell RH, Kramvis A. Occult hepatitis B virus infection in chacma baboons, South Africa. Emerging Infectious Diseases. 19: 598-605. PMID 23631817 DOI: 10.3201/eid1904.121107  0.066
1994 Mannucci PM, Gdovin S, Gringeri A, Colombo M, Mele A, Schinaia N, Ciavarella N, Emerson SU, Purcell RH. Transmission of hepatitis A to patients with hemophilia by factor VIII concentrates treated with organic solvent and detergent to inactivate viruses. The Italian Collaborative Group. Annals of Internal Medicine. 120: 1-7. PMID 7504424 DOI: 10.7326/0003-4819-120-1-199401010-00001  0.066
1999 Farci P, Munoz SJ, Shimoda A, Govindarajan S, Wong DC, Coiana A, Peddis G, Rubin R, Purcell RH. Experimental transmission of hepatitis C virus-associated fulminant hepatitis to a chimpanzee. The Journal of Infectious Diseases. 179: 1007-11. PMID 10068599 DOI: 10.1086/314653  0.066
2002 Meng XJ, Wiseman B, Elvinger F, Guenette DK, Toth TE, Engle RE, Emerson SU, Purcell RH. Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries. Journal of Clinical Microbiology. 40: 117-22. PMID 11773103 DOI: 10.1128/Jcm.40.1.117-122.2002  0.066
2000 Cote PJ, Korba BE, Miller RH, Jacob JR, Baldwin BH, Hornbuckle WE, Purcell RH, Tennant BC, Gerin JL. Effects of age and viral determinants on chronicity as an outcome of experimental woodchuck hepatitis virus infection. Hepatology (Baltimore, Md.). 31: 190-200. PMID 10613745 DOI: 10.1002/Hep.510310128  0.066
2000 Forns X, Payette PJ, Ma X, Satterfield W, Eder G, Mushahwar IK, Govindarajan S, Davis HL, Emerson SU, Purcell RH, Bukh J. Vaccination of chimpanzees with plasmid DNA encoding the hepatitis C virus (HCV) envelope E2 protein modified the infection after challenge with homologous monoclonal HCV. Hepatology (Baltimore, Md.). 32: 618-25. PMID 10960458 DOI: 10.1053/jhep.2000.9877  0.066
1993 Emerson SU, Huang YK, Purcell RH. 2B and 2C mutations are essential but mutations throughout the genome of HAV contribute to adaptation to cell culture. Virology. 194: 475-80. PMID 8389072 DOI: 10.1006/viro.1993.1286  0.066
2015 Bukh J, Engle RE, Faulk K, Wang RY, Farci P, Alter HJ, Purcell RH. Immunoglobulin with High-Titer In-vitro Cross Neutralizing Hepatitis C Virus Antibody Passively Protects Chimpanzee from Homologous, but not Heterologous Challenge. Journal of Virology. PMID 26085160 DOI: 10.1128/Jvi.01194-15  0.065
1998 Smedile A, Casey JL, Cote PJ, Durazzo M, Lavezzo B, Purcell RH, Rizzetto M, Gerin JL. Hepatitis D viremia following orthotopic liver transplantation involves a typical HDV virion with a hepatitis B surface antigen envelope. Hepatology (Baltimore, Md.). 27: 1723-9. PMID 9620349 DOI: 10.1002/Hep.510270636  0.065
1991 Ponzetto A, Negro F, Gerin JL, Purcell RH. Experimental hepatitis delta virus infection in the animal model. Progress in Clinical and Biological Research. 364: 147-57. PMID 2020690  0.064
1999 Meng XJ, Dea S, Engle RE, Friendship R, Lyoo YS, Sirinarumitr T, Urairong K, Wang D, Wong D, Yoo D, Zhang Y, Purcell RH, Emerson SU. Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population. Journal of Medical Virology. 59: 297-302. PMID 10502259 DOI: 10.1002/(Sici)1096-9071(199911)59:3<297::Aid-Jmv6>3.0.Co;2-3  0.064
1993 Tedeschi V, Purcell RH, Emerson SU. Partial characterization of hepatitis A viruses from three intermediate passage levels of a series resulting in adaptation to growth in cell culture and attenuation of virulence. Journal of Medical Virology. 39: 16-22. PMID 8380839  0.064
1996 Farci P, Alter HJ, Shimoda A, Govindarajan S, Cheung LC, Melpolder JC, Sacher RA, Shih JW, Purcell RH. Hepatitis C virus-associated fulminant hepatic failure. The New England Journal of Medicine. 335: 631-4. PMID 8687517 DOI: 10.1056/Nejm199608293350904  0.064
2000 Allander T, Forns X, Emerson SU, Purcell RH, Bukh J. Hepatitis C virus envelope protein E2 binds to CD81 of tamarins. Virology. 277: 358-67. PMID 11080483 DOI: 10.1006/viro.2000.0617  0.064
1992 Bukh J, Purcell RH, Miller RH. Sequence analysis of the 5' noncoding region of hepatitis C virus. Proceedings of the National Academy of Sciences of the United States of America. 89: 4942-6. PMID 1317578  0.063
2001 Emerson SU, Purcell RH. Recombinant vaccines for hepatitis E. Trends in Molecular Medicine. 7: 462-6. PMID 11597521 DOI: 10.1016/S1471-4914(01)02106-2  0.063
1990 Shimizu YK, Weiner AJ, Rosenblatt J, Wong DC, Shapiro M, Popkin T, Houghton M, Alter HJ, Purcell RH. Early events in hepatitis C virus infection of chimpanzees. Proceedings of the National Academy of Sciences of the United States of America. 87: 6441-4. PMID 2117282 DOI: 10.1073/Pnas.87.16.6441  0.063
1989 Cohen JI, Feinstone S, Purcell RH. Hepatitis A virus infection in a chimpanzee: duration of viremia and detection of virus in saliva and throat swabs. The Journal of Infectious Diseases. 160: 887-90. PMID 2572653 DOI: 10.1093/infdis/160.5.887  0.063
1991 Farci P, Alter HJ, Wong D, Miller RH, Shih JW, Jett B, Purcell RH. A long-term study of hepatitis C virus replication in non-A, non-B hepatitis. The New England Journal of Medicine. 325: 98-104. PMID 1646962 DOI: 10.1056/Nejm199107113250205  0.063
2015 Chen Z, Schneerson R, Lovchik JA, Dai Z, Kubler-Kielb J, Agulto L, Leppla SH, Purcell RH. Bacillus anthracis capsular conjugates elicit chimpanzee polyclonal antibodies that protect mice from pulmonary anthrax. Clinical and Vaccine Immunology : Cvi. PMID 26041039 DOI: 10.1128/CVI.00137-15  0.062
1996 Shimizu YK, Igarashi H, Kiyohara T, Cabezon T, Farci P, Purcell RH, Yoshikura H. A hyperimmune serum against a synthetic peptide corresponding to the hypervariable region 1 of hepatitis C virus can prevent viral infection in cell cultures. Virology. 223: 409-12. PMID 8806581 DOI: 10.1006/viro.1996.0497  0.062
2009 Asabe S, Wieland SF, Chattopadhyay PK, Roederer M, Engle RE, Purcell RH, Chisari FV. The size of the viral inoculum contributes to the outcome of hepatitis B virus infection. Journal of Virology. 83: 9652-62. PMID 19625407 DOI: 10.1128/Jvi.00867-09  0.062
1998 Arankalle VA, Chadha MS, Dama BM, Tsarev SA, Purcell RH, Banerjee K. Role of immune serum globulins in pregnant women during an epidemic of hepatitis E. Journal of Viral Hepatitis. 5: 199-204. PMID 9658374 DOI: 10.1046/j.1365-2893.1998.00096.x  0.061
1994 Lai ME, Mazzoleni AP, Argiolu F, De Virgilis S, Balestrieri A, Purcell RH, Cao A, Farci P. Hepatitis C virus in multiple episodes of acute hepatitis in polytransfused thalassaemic children. Lancet. 343: 388-90. PMID 7905553 DOI: 10.1016/S0140-6736(94)91224-6  0.061
2002 Smith HM, Reporter R, Rood MP, Linscott AJ, Mascola LM, Hogrefe W, Purcell RH. Prevalence study of antibody to ratborne pathogens and other agents among patients using a free clinic in downtown Los Angeles. The Journal of Infectious Diseases. 186: 1673-6. PMID 12447746 DOI: 10.1086/345377  0.06
2002 Purcell RH, Wong DC, Shapiro M. Relative infectivity of hepatitis A virus by the oral and intravenous routes in 2 species of nonhuman primates. The Journal of Infectious Diseases. 185: 1668-71. PMID 12023776 DOI: 10.1086/340520  0.06
2001 Bukh J, Apgar CL, Govindarajan S, Emerson SU, Purcell RH. Failure to infect rhesus monkeys with hepatitis C virus strains of genotypes 1a, 2a or 3a. Journal of Viral Hepatitis. 8: 228-31. PMID 11380802 DOI: 10.1046/j.1365-2893.2001.00284.x  0.06
2014 Wieland SF, Asabe S, Engle RE, Purcell RH, Chisari FV. Limited hepatitis B virus replication space in the chronically hepatitis C virus-infected liver. Journal of Virology. 88: 5184-8. PMID 24522924 DOI: 10.1128/Jvi.03553-13  0.06
2008 Engle RE, Russell RS, Purcell RH, Bukh J. Development of a TaqMan assay for the six major genotypes of hepatitis C virus: comparison with commercial assays. Journal of Medical Virology. 80: 72-9. PMID 18041021 DOI: 10.1002/jmv.21043  0.059
2009 Blackard JT, Rouster SD, Nady S, Galal G, Marzuuk N, Rafaat MM, Daef E, El Din SS, Purcell RH, Emerson SU, Sherman KE, Shata MT. Genotypic characterization of symptomatic hepatitis E virus (HEV) infections in Egypt. Journal of Clinical Virology : the Official Publication of the Pan American Society For Clinical Virology. 46: 140-4. PMID 19651539 DOI: 10.1016/J.Jcv.2009.07.007  0.059
2006 Hsia CC, Purcell RH, Farshid M, Lachenbruch PA, Yu MY. Quantification of hepatitis B virus genomes and infectivity in human serum samples. Transfusion. 46: 1829-35. PMID 17002641 DOI: 10.1111/j.1537-2995.2006.00974.x  0.059
1989 Alter HJ, Purcell RH, Shih JW, Melpolder JC, Houghton M, Choo QL, Kuo G. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. The New England Journal of Medicine. 321: 1494-500. PMID 2509915 DOI: 10.1056/Nejm198911303212202  0.059
1993 Hijikata M, Shimizu YK, Kato H, Iwamoto A, Shih JW, Alter HJ, Purcell RH, Yoshikura H. Equilibrium centrifugation studies of hepatitis C virus: evidence for circulating immune complexes. Journal of Virology. 67: 1953-8. PMID 8383220 DOI: 10.1128/jvi.67.4.1953-1958.1993  0.058
1999 Kabrane-Lazizi Y, Fine JB, Elm J, Glass GE, Higa H, Diwan A, Gibbs CJ, Meng XJ, Emerson SU, Purcell RH. Evidence for widespread infection of wild rats with hepatitis E virus in the United States. The American Journal of Tropical Medicine and Hygiene. 61: 331-5. PMID 10463689  0.058
1997 Shimizu YK, Igarashi H, Kanematu T, Fujiwara K, Wong DC, Purcell RH, Yoshikura H. Sequence analysis of the hepatitis C virus genome recovered from serum, liver, and peripheral blood mononuclear cells of infected chimpanzees. Journal of Virology. 71: 5769-73. PMID 9223464  0.058
1994 Yin S, Purcell RH, Emerson SU. A new Chinese isolate of hepatitis E virus: comparison with strains recovered from different geographical regions. Virus Genes. 9: 23-32. PMID 7871758  0.058
1994 Bryan JP, Tsarev SA, Iqbal M, Ticehurst J, Emerson S, Ahmed A, Duncan J, Rafiqui AR, Malik IA, Purcell RH. Epidemic hepatitis E in Pakistan: patterns of serologic response and evidence that antibody to hepatitis E virus protects against disease. The Journal of Infectious Diseases. 170: 517-21. PMID 8077708  0.058
2007 Zhou YH, Chen Z, Purcell RH, Emerson SU. Positive reactions on Western blots do not necessarily indicate the epitopes on antigens are continuous. Immunology and Cell Biology. 85: 73-8. PMID 17130902 DOI: 10.1038/sj.icb.7100004  0.057
1992 Kelen GD, Green GB, Purcell RH, Chan DW, Qaqish BF, Sivertson KT, Quinn TC. Hepatitis B and hepatitis C in emergency department patients. The New England Journal of Medicine. 326: 1399-404. PMID 1373867 DOI: 10.1056/Nejm199205213262105  0.057
1993 Kew MC, Chestnut T, Baldwin BH, Hornbuckle WE, Tennant BC, Purcell RH, Miller RH. Heterogeneity of the woodchuck hepatitis virus genome in a chronically infected woodchuck. Virus Research. 27: 229-37. PMID 8488722  0.057
2001 Bryan JP, Reyes L, Hakre S, Gloria R, Kishore GM, Tillett W, Engle R, Tsarev S, Cruess D, Purcell RH. Epidemiology of acute hepatitis in the Stann Creek District of Belize, Central America. The American Journal of Tropical Medicine and Hygiene. 65: 318-24. PMID 11693876  0.057
2006 Bukh J, Purcell RH. A milestone for hepatitis C virus research: a virus generated in cell culture is fully viable in vivo. Proceedings of the National Academy of Sciences of the United States of America. 103: 3500-1. PMID 16505349 DOI: 10.1073/pnas.0600551103  0.056
2002 Zhang M, Emerson SU, Nguyen H, Engle R, Govindarajan S, Blackwelder WC, Gerin J, Purcell RH. Recombinant vaccine against hepatitis E: duration of protective immunity in rhesus macaques. Vaccine. 20: 3285-91. PMID 12213398 DOI: 10.1016/S0264-410X(02)00314-6  0.056
2011 Meunier JC, Bukh J, Diaz G, Tovo PA, Casadei AM, Quinti I, Iorio R, Emerson S, Purcell RH, Farci P. Neutralizing antibodies to hepatitis C virus in perinatally infected children followed up prospectively. The Journal of Infectious Diseases. 204: 1741-5. PMID 22006993 DOI: 10.1093/infdis/jir631  0.055
2005 Zhou YH, Purcell RH, Emerson SU. A truncated ORF2 protein contains the most immunogenic site on ORF2: antibody responses to non-vaccine sequences following challenge of vaccinated and non-vaccinated macaques with hepatitis E virus. Vaccine. 23: 3157-65. PMID 15837215 DOI: 10.1016/j.vaccine.2004.12.020  0.055
2011 Davern TJ, Chalasani N, Fontana RJ, Hayashi PH, Protiva P, Kleiner DE, Engle RE, Nguyen H, Emerson SU, Purcell RH, Tillmann HL, Gu J, Serrano J, Hoofnagle JH. Acute hepatitis E infection accounts for some cases of suspected drug-induced liver injury. Gastroenterology. 141: 1665-72.e1-9. PMID 21855518 DOI: 10.1053/j.gastro.2011.07.051  0.055
2002 Bryan JP, Iqbal M, Tsarev S, Malik IA, Duncan JF, Ahmed A, Khan A, Khan A, Rafiqui AR, Purcell RH, Legters LJ. Epidemic of hepatitis E in a military unit in Abbotrabad, Pakistan. The American Journal of Tropical Medicine and Hygiene. 67: 662-8. PMID 12518859 DOI: 10.4269/AJTMH.2002.67.662  0.055
1991 Emerson SU, McRill C, Rosenblum B, Feinstone S, Purcell RH. Mutations responsible for adaptation of hepatitis A virus to efficient growth in cell culture. Journal of Virology. 65: 4882-6. PMID 1651411  0.055
2003 Schofield DJ, Purcell RH, Nguyen HT, Emerson SU. Monoclonal antibodies that neutralize HEV recognize an antigenic site at the carboxyterminus of an ORF2 protein vaccine. Vaccine. 22: 257-67. PMID 14615154 DOI: 10.1016/j.vaccine.2003.07.008  0.054
2012 Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, Boucher EN, Wang Y, Cheslock PS, Knauber M, Olsen DB, Ludmerer SW, Szabo G, Finberg RW, Purcell RH, Lanford RE, et al. Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees. Plos Pathogens. 8: e1002895. PMID 22952447 DOI: 10.1371/Journal.Ppat.1002895  0.054
1993 Bukh J, Wantzin P, Krogsgaard K, Knudsen F, Purcell RH, Miller RH. High prevalence of hepatitis C virus (HCV) RNA in dialysis patients: failure of commercially available antibody tests to identify a significant number of patients with HCV infection. Copenhagen Dialysis HCV Study Group. The Journal of Infectious Diseases. 168: 1343-8. PMID 7504031  0.054
2001 Kabrane-Lazizi Y, Zhang M, Purcell RH, Miller KD, Davey RT, Emerson SU. Acute hepatitis caused by a novel strain of hepatitis E virus most closely related to United States strains. The Journal of General Virology. 82: 1687-93. PMID 11413380 DOI: 10.1099/0022-1317-82-7-1687  0.054
2011 Meunier JC, Gottwein JM, Houghton M, Russell RS, Emerson SU, Bukh J, Purcell RH. Vaccine-induced cross-genotype reactive neutralizing antibodies against hepatitis C virus. The Journal of Infectious Diseases. 204: 1186-90. PMID 21917891 DOI: 10.1093/Infdis/Jir511  0.053
2003 Thimme R, Wieland S, Steiger C, Ghrayeb J, Reimann KA, Purcell RH, Chisari FV. CD8(+) T cells mediate viral clearance and disease pathogenesis during acute hepatitis B virus infection. Journal of Virology. 77: 68-76. PMID 12477811 DOI: 10.1128/Jvi.77.1.68-76.2003  0.053
2008 Union A, Buyse M, Verheyden G, De Brabandere V, Van Put H, Vandenneucker C, Jacobs D, Devos A, Defruyt M, Schryvers N, Dauwe M, Purcell R, Maertens G, Allosery K. 118 GENERATION OF RECOMBINANT HUMAN ANTI-E1 MONOCLONAL ANTIBODIES THAT EFFECTIVELY NEUTRALIZE HCV IN VITRO Journal of Hepatology. 48: S52. DOI: 10.1016/S0168-8278(08)60120-8  0.053
1995 Tsarev SA, Tsareva TS, Emerson SU, Rippy MK, Zack P, Shapiro M, Purcell RH. Experimental hepatitis E in pregnant rhesus monkeys: failure to transmit hepatitis E virus (HEV) to offspring and evidence of naturally acquired antibodies to HEV. The Journal of Infectious Diseases. 172: 31-7. PMID 7797939  0.053
2003 Yu C, Engle RE, Bryan JP, Emerson SU, Purcell RH. Detection of immunoglobulin M antibodies to hepatitis E virus by class capture enzyme immunoassay. Clinical and Diagnostic Laboratory Immunology. 10: 579-86. PMID 12853389 DOI: 10.1128/CDLI.10.4.579-586.2003  0.052
1993 Yin S, Tsarev SA, Purcell RH, Emerson SU. Partial sequence comparison of eight new Chinese strains of hepatitis E virus suggests the genome sequence is relatively stable. Journal of Medical Virology. 41: 230-41. PMID 8263504  0.052
2000 Fix AD, Abdel-Hamid M, Purcell RH, Shehata MH, Abdel-Aziz F, Mikhail N, el Sebai H, Nafeh M, Habib M, Arthur RR, Emerson SU, Strickland GT. Prevalence of antibodies to hepatitis E in two rural Egyptian communities. The American Journal of Tropical Medicine and Hygiene. 62: 519-23. PMID 11220771  0.051
1997 Tsarev SA, Tsareva TS, Emerson SU, Govindarajan S, Shapiro M, Gerin JL, Purcell RH. Recombinant vaccine against hepatitis E: dose response and protection against heterologous challenge. Vaccine. 15: 1834-8. PMID 9413090 DOI: 10.1016/S0264-410X(97)00145-X  0.051
1992 Bukh J, Purcell RH, Miller RH. Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay. Proceedings of the National Academy of Sciences of the United States of America. 89: 187-91. PMID 1309604  0.051
1990 Kiyosawa K, Sodeyama T, Tanaka E, Gibo Y, Yoshizawa K, Nakano Y, Furuta S, Akahane Y, Nishioka K, Purcell RH. Interrelationship of blood transfusion, non-A, non-B hepatitis and hepatocellular carcinoma: analysis by detection of antibody to hepatitis C virus. Hepatology (Baltimore, Md.). 12: 671-5. PMID 2170265 DOI: 10.1002/Hep.1840120409  0.051
1990 Wong DC, Diwan AR, Rosen L, Gerin JL, Johnson RG, Polito A, Purcell RH. Non-specificity of anti-HCV test for seroepidemiological analysis. Lancet. 336: 750-1. PMID 1975921  0.051
2006 Murray JM, Purcell RH, Wieland SF. The half-life of hepatitis B virions. Hepatology (Baltimore, Md.). 44: 1117-21. PMID 17058221 DOI: 10.1002/hep.21364  0.051
1989 Shimizu YK, Purcell RH. Cytoplasmic antigen in hepatocytes of chimpanzees infected with non-A, non-B hepatitis virus or hepatitis delta virus: relationship to interferon. Hepatology (Baltimore, Md.). 10: 764-8. PMID 2478436  0.05
1990 Smedile A, Bergmann KF, Baroudy BM, Wells FV, Purcell RH, Bonino F, Rizzetto M, Gerin JL. Riboprobe assay for HDV RNA: a sensitive method for the detection of the HDV genome in clinical serum samples. Journal of Medical Virology. 30: 20-4. PMID 2406372  0.049
1997 Chatterjee R, Tsarev S, Pillot J, Coursaget P, Emerson SU, Purcell RH. African strains of hepatitis E virus that are distinct from Asian strains. Journal of Medical Virology. 53: 139-44. PMID 9334924 DOI: 10.1002/(SICI)1096-9071(199710)53:2<139::AID-JMV5>3.0.CO;2-A  0.049
2015 Holm DK, Moessner BK, Engle RE, Zaaijer HL, Georgsen J, Purcell RH, Christensen PB. Declining prevalence of hepatitis E antibodies among Danish blood donors. Transfusion. 55: 1662-7. PMID 25819381 DOI: 10.1111/trf.13028  0.049
2005 Emerson SU, Arankalle VA, Purcell RH. Thermal stability of hepatitis E virus. The Journal of Infectious Diseases. 192: 930-3. PMID 16088844 DOI: 10.1086/432488  0.048
1989 Negro F, Shapiro M, Satterfield WC, Gerin JL, Purcell RH. Reappearance of hepatitis D virus (HDV) replication in chronic hepatitis B virus carrier chimpanzees rechallenged with HDV. The Journal of Infectious Diseases. 160: 567-71. PMID 2794555  0.048
2014 Engle RE, Bukh J, Alter HJ, Emerson SU, Trenbeath JL, Nguyen HT, Brockington A, Mitra T, Purcell RH. Transfusion-associated hepatitis before the screening of blood for hepatitis risk factors. Transfusion. 54: 2833-41. PMID 24797372 DOI: 10.1111/Trf.12682  0.047
2006 Payette PJ, Ma X, Weeratna RD, McCluskie MJ, Shapiro M, Engle RE, Davis HL, Purcell RH. Testing of CpG-optimized protein and DNA vaccines against the hepatitis B virus in chimpanzees for immunogenicity and protection from challenge. Intervirology. 49: 144-51. PMID 16428890 DOI: 10.1159/000089375  0.047
2001 Kabrane-Lazizi Y, Emerson SU, Herzog C, Purcell RH. Detection of antibodies to HAV 3C proteinase in experimentally infected chimpanzees and in naturally infected children. Vaccine. 19: 2878-83. PMID 11282198 DOI: 10.1016/S0264-410X(00)00560-0  0.047
1992 Purcell RH, D'Hondt E, Bradbury R, Emerson SU, Govindarajan S, Binn L. Inactivated hepatitis A vaccine: active and passive immunoprophylaxis in chimpanzees. Vaccine. 10: S148-51. PMID 1335648  0.046
2000 Purcell RH. Hepatitis B virus mutants and efficacy of vaccination. Lancet. 356: 769-70. PMID 11085716 DOI: 10.1016/S0140-6736(05)73670-9  0.046
1991 Tsarev SA, Emerson SU, Balayan MS, Ticehurst J, Purcell RH. Simian hepatitis A virus (HAV) strain AGM-27: comparison of genome structure and growth in cell culture with other HAV strains. The Journal of General Virology. 72: 1677-83. PMID 1649901  0.046
1993 Miller RH, Bukh J, Purcell RH. Importance of the polymerase chain reaction in the study of hepatitis C virus infection. International Journal of Clinical & Laboratory Research. 23: 139-45. PMID 8400334  0.044
1991 Jupp PG, Purcell RH, Phillips JM, Shapiro M, Gerin JL. Attempts to transmit hepatitis B virus to chimpanzees by arthropods. South African Medical Journal = Suid-Afrikaanse Tydskrif Vir Geneeskunde. 79: 320-2. PMID 2017742  0.044
1998 Chen HS, Miller RH, Hornbuckle WE, Tennant BC, Cote PJ, Gerin JL, Purcell RH. Titration of recombinant woodchuck hepatitis virus DNA in adult woodchucks. Journal of Medical Virology. 54: 92-4. PMID 9496365 DOI: 10.1002/(SICI)1096-9071(199802)54:2<92::AID-JMV4>3.0.CO;2-J  0.044
2000 Farci P, Shimoda A, Coiana A, Diaz G, Peddis G, Melpolder JC, Strazzera A, Chien DY, Munoz SJ, Balestrieri A, Purcell RH, Alter HJ, Tellier R. Hepatitis C virus: The advantages of diversity Pediatric Research. 48: 577. PMID 11044471  0.043
2004 Yu MY, Bartosch B, Zhang P, Guo ZP, Renzi PM, Shen LM, Granier C, Feinstone SM, Cosset FL, Purcell RH. Neutralizing antibodies to hepatitis C virus (HCV) in immune globulins derived from anti-HCV-positive plasma. Proceedings of the National Academy of Sciences of the United States of America. 101: 7705-10. PMID 15136748 DOI: 10.1073/pnas.0402458101  0.043
1993 Purcell RH. The discovery of the hepatitis viruses. Gastroenterology. 104: 955-63. PMID 8385046  0.043
2003 Schofield DJ, Emerson SU, Purcell RH. Four chimpanzee monoclonal antibodies that neutralize hepatitis A virus Drugs of the Future. 28: 137-142. DOI: 10.1358/dof.2003.028.02.856927  0.042
1992 Farci P, London WT, Wong DC, Dawson GJ, Vallari DS, Engle R, Purcell RH. The natural history of infection with hepatitis C virus (HCV) in chimpanzees: comparison of serologic responses measured with first- and second-generation assays and relationship to HCV viremia. The Journal of Infectious Diseases. 165: 1006-11. PMID 1374781  0.042
1991 Negro F, Gerin JL, Purcell RH, Miller R. Sequence homology between HDV RNA and 7SL RNA: implications for pathogenesis. Progress in Clinical and Biological Research. 364: 327-32. PMID 1850528  0.042
1998 Mast EE, Alter MJ, Holland PV, Purcell RH. Evaluation of assays for antibody to hepatitis E virus by a serum panel. Hepatitis E Virus Antibody Serum Panel Evaluation Group. Hepatology (Baltimore, Md.). 27: 857-61. PMID 9500718 DOI: 10.1002/hep.510270331  0.041
2003 Purcell RH, Nguyen H, Shapiro M, Engle RE, Govindarajan S, Blackwelder WC, Wong DC, Prieels JP, Emerson SU. Pre-clinical immunogenicity and efficacy trial of a recombinant hepatitis E vaccine. Vaccine. 21: 2607-15. PMID 12744897 DOI: 10.1016/S0264-410X(03)00100-2  0.041
1993 Shimizu YK, Purcell RH, Yoshikura H. Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 6037-41. PMID 8392185  0.041
2007 Purcell RH, Emerson SU. Natural History and Experimental Models Viral Hepatitis. 109-125. DOI: 10.1002/9780470987131.ch8  0.041
1992 Tsarev SA, Emerson SU, Reyes GR, Tsareva TS, Legters LJ, Malik IA, Iqbal M, Purcell RH. Characterization of a prototype strain of hepatitis E virus. Proceedings of the National Academy of Sciences of the United States of America. 89: 559-63. PMID 1731327  0.041
2014 Debing Y, Emerson SU, Purcell RH, Neyts J, Dallmeier K. Complete genome sequence of a rat hepatitis e virus strain isolated in the United States. Genome Announcements. 2. PMID 25377700 DOI: 10.1128/genomeA.01096-14  0.041
1992 Sjogren MH, Purcell RH, McKee K, Binn L, Macarthy P, Ticehurst J, Feinstone S, Caudill J, See A, Hoke C. Clinical and laboratory observations following oral or intramuscular administration of a live attenuated hepatitis A vaccine candidate. Vaccine. 10: S135-7. PMID 1335645  0.04
1991 Negro F, Emerson SU, McRill C, Bonino F, Craxi A, Gerin JL, Miller RH, Purcell RH. A polymerase-chain reaction-based assay for serum HDV RNA. Progress in Clinical and Biological Research. 364: 179-84. PMID 2020693  0.04
1995 D'Hondt E, Purcell RH, Emerson SU, Wong DC, Shapiro M, Govindarajan S. Efficacy of an inactivated hepatitis A vaccine in pre- and postexposure conditions in marmosets. The Journal of Infectious Diseases. 171: S40-3. PMID 7876647  0.04
1996 Davis HL, McCluskie MJ, Gerin JL, Purcell RH. DNA vaccine for hepatitis B: evidence for immunogenicity in chimpanzees and comparison with other vaccines. Proceedings of the National Academy of Sciences of the United States of America. 93: 7213-8. PMID 8692971 DOI: 10.1073/pnas.93.14.7213  0.039
1997 Stewart DR, Morris TS, Purcell RH, Emerson SU. Detection of antibodies to the nonstructural 3C proteinase of hepatitis A virus. The Journal of Infectious Diseases. 176: 593-601. PMID 9291304  0.039
1995 Purcell RH. Hepatitis C and its sequelae: the biology of hepatitis C virus and implications for its control. Princess Takamatsu Symposia. 25: 1-13. PMID 8875604  0.039
1997 Chengalvala MV, Bhat BM, Bhat RA, Dheer SK, Lubeck MD, Purcell RH, Murthy KK. Replication and immunogenicity of Ad7-, Ad4-, and Ad5-hepatitis B virus surface antigen recombinants, with or without a portion of E3 region, in chimpanzees. Vaccine. 15: 335-9. PMID 9139496  0.039
2020 Albert H, Purcell R, Wang YY, Kao K, Mareka M, Katz Z, Maama BL, Mots'oane T. Designing an optimized diagnostic network to improve access to TB diagnosis and treatment in Lesotho. Plos One. 15: e0233620. PMID 32492022 DOI: 10.1371/journal.pone.0233620  0.038
1995 Arankalle VA, Tsarev SA, Chadha MS, Alling DW, Emerson SU, Banerjee K, Purcell RH. Age-specific prevalence of antibodies to hepatitis A and E viruses in Pune, India, 1982 and 1992. The Journal of Infectious Diseases. 171: 447-50. PMID 7844387  0.038
1996 Heller T, Yin S, Tsarev SA, Purcell RH, Emerson SU. False-positive serologic test resulting from a probable yeast infection in a chimpanzee. Clinical and Diagnostic Laboratory Immunology. 3: 614-5. PMID 8877148  0.037
2002 Forns X, Bukh J, Purcell RH. The challenge of developing a vaccine against hepatitis C virus. Journal of Hepatology. 37: 684-95. PMID 12399239 DOI: 10.1016/S0168-8278(02)00308-2  0.037
1994 Arankalle VA, Chadha MS, Tsarev SA, Emerson SU, Risbud AR, Banerjee K, Purcell RH. Seroepidemiology of water-borne hepatitis in India and evidence for a third enterically-transmitted hepatitis agent. Proceedings of the National Academy of Sciences of the United States of America. 91: 3428-32. PMID 8159764  0.037
2010 Purcell RH, Emerson SU. Hidden danger: the raw facts about hepatitis E virus. The Journal of Infectious Diseases. 202: 819-21. PMID 20695795 DOI: 10.1086/655900  0.036
1997 Farci P, Bukh J, Purcell RH. The quasispecies of hepatitis C virus and the host immune response. Springer Seminars in Immunopathology. 19: 5-26. PMID 9266628 DOI: 10.1007/BF00945022  0.036
1994 Tsarev SA, Tsareva TS, Emerson SU, Yarbough PO, Legters LJ, Moskal T, Purcell RH. Infectivity titration of a prototype strain of hepatitis E virus in cynomolgus monkeys. Journal of Medical Virology. 43: 135-42. PMID 8083660  0.036
2004 Farci P, Roskams T, Chessa L, Peddis G, Mazzoleni AP, Scioscia R, Serra G, Lai ME, Loy M, Caruso L, Desmet V, Purcell RH, Balestrieri A. Long-term benefit of interferon alpha therapy of chronic hepatitis D: regression of advanced hepatic fibrosis. Gastroenterology. 126: 1740-9. PMID 15188169 DOI: 10.1053/j.gastro.2004.03.017  0.035
1995 Xu ZY, Duan SC, Margolis HS, Purcell RH, Ou-Yang PY, Coleman PJ, Zhuang YL, Xu HF, Qian SG, Zhu QR. Long-term efficacy of active postexposure immunization of infants for prevention of hepatitis B virus infection. United States-People's Republic of China Study Group on Hepatitis B. The Journal of Infectious Diseases. 171: 54-60. PMID 7798683  0.034
1990 Kaneko S, Miller RH, Di Bisceglie AM, Feinstone SM, Hoofnagle JH, Purcell RH. Detection of hepatitis B virus DNA in serum by polymerase chain reaction. Application for clinical diagnosis. Gastroenterology. 99: 799-804. PMID 2116344  0.034
1993 Bukh J, Miller RH, Kew MC, Purcell RH. Hepatitis C virus RNA in southern African blacks with hepatocellular carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 90: 1848-51. PMID 8383330  0.033
1990 Purcell RH. Enterically transmitted non-A, non-B hepatitis. Progress in Liver Diseases. 9: 497-504. PMID 2156310  0.033
2006 Wang CYJ, Xing L, Li TC, Takeda N, Yasutomi Y, Schofield DJ, Emerson SU, Purcell RH, Miyamura T, Cheng RH. Structural identification of recombinant HEV VLP C-terminus Microscopy and Microanalysis. 12: 416-417. DOI: 10.1017/S1431927606060521  0.033
2000 Purcell RH, Emerson SU. Hepatitis E virus infection. Lancet. 355: 578. PMID 10683033 DOI: 10.1016/S0140-6736(05)73231-1  0.033
1996 Shimizu YK, Feinstone SM, Kohara M, Purcell RH, Yoshikura H. Hepatitis C virus: detection of intracellular virus particles by electron microscopy. Hepatology (Baltimore, Md.). 23: 205-9. PMID 8591842 DOI: 10.1002/hep.510230202  0.032
2000 Purcell RH, Alter HJ, Dienstag JL. Non-A, non-B hepatitis. 1976. The Yale Journal of Biology and Medicine. 73: 175-82. PMID 11765936  0.031
1995 Farci P, Orgiana G, Purcell RH. Immunity elicited by hepatitis C virus. Clinical and Experimental Rheumatology. 13: S9-12. PMID 8730469  0.031
2015 Kuniholm MH, Engle RE, Purcell RH, Nelson KE. Hepatitis E virus seroprevalence in the United States: no easy answers. Hepatology (Baltimore, Md.). 61: 1441-2. PMID 24995930 DOI: 10.1002/Hep.27286  0.031
2003 Tellier R, Bukh J, Emerson SU, Purcell RH. Long PCR methodology. Methods in Molecular Biology (Clifton, N.J.). 226: 173-8. PMID 12958498 DOI: 10.1385/1-59259-384-4:173  0.03
1994 Purcell RH. Hepatitis C virus: historical perspective and current concepts. Fems Microbiology Reviews. 14: 181-91. PMID 8086193  0.03
2015 Engle RE, Kuniholm MH, Nelson KE, Purcell RH. Hepatitis E virus seroprevalence in the National Health and Nutrition Examination Survey: facts trump opinion. Hepatology (Baltimore, Md.). 61: 1442. PMID 24995541 DOI: 10.1002/Hep.27292  0.029
2004 Emerson SU, Purcell RH. Running like water--the omnipresence of hepatitis E. The New England Journal of Medicine. 351: 2367-8. PMID 15575050 DOI: 10.1056/NEJMp048285  0.027
1990 Tassopoulos NC, Sjogren MH, Purcell RH. 19S and 7-8S forms of IgM antibody to hepatitis B core antigen in acute icteric hepatitis superimposed on hepatitis B surface antigen carriage. Infection. 18: 376-80. PMID 2127587  0.027
1990 Kaneko S, Miller RH, Di Bisceglie A, Feinstone SM, Hoofnagle JH, Purcell RH. Hepatitis B virus DNA detection and comparison with hepatitis B surface antigen. Gastroenterologia Japonica. 25: 57-61. PMID 2227267  0.026
2013 Maddukuri VC, Russo MW, Ahrens WA, Emerson SU, Engle RE, Purcell RH, Thompson EB, Bonkovsky HL. Chronic hepatitis E with neurologic manifestations and rapid progression of liver fibrosis in a liver transplant recipient. Digestive Diseases and Sciences. 58: 2413-6. PMID 23512404 DOI: 10.1007/s10620-013-2628-7  0.026
2008 Christensen PB, Engle RE, Hjort C, Homburg KM, Vach W, Georgsen J, Purcell RH. Time trend of the prevalence of hepatitis E antibodies among farmers and blood donors: a potential zoonosis in Denmark. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 47: 1026-31. PMID 18781880 DOI: 10.1086/591970  0.026
1994 Purcell RH, Mannucci PM, Gdovin S, Gringeri A, Colombo M, Mele A, Schinaia N, Ciavarella N, Emerson SU. Virology of the hepatitis A epidemic in Italy. Vox Sanguinis. 67: 2-7; discussion 24-6. PMID 7831866  0.025
1991 Kiyosawa K, Sodeyama T, Tanaka E, Nakano Y, Furuta S, Nishioka K, Purcell RH, Alter HJ. Hepatitis C in hospital employees with needlestick injuries. Annals of Internal Medicine. 115: 367-9. PMID 1907441 DOI: 10.7326/0003-4819-115-5-367  0.023
1995 Schultheiss T, Emerson SU, Purcell RH, Gauss-Müller V. Polyprotein processing in echovirus 22: a first assessment. Biochemical and Biophysical Research Communications. 217: 1120-7. PMID 8554566  0.021
1993 Purcell RH. Control of hepatitis A by inactivated vaccines: unanswered questions and unresolved issues. Journal of Hepatology. 18: S61-4. PMID 8182277  0.02
2012 Hoofnagle JH, Nelson KE, Purcell RH. Hepatitis E. The New England Journal of Medicine. 367: 1237-44. PMID 23013075 DOI: 10.1056/NEJMra1204512  0.018
2007 Emerson SU, Purcell RH. Hepatitis E. The Pediatric Infectious Disease Journal. 26: 1147-8. PMID 18043454 DOI: 10.1097/INF.0b013e31815dd7c2  0.018
2012 Purcell RH, Emerson SU. Hepatitis E vaccines Vaccines: Sixth Edition. 1085-1089. DOI: 10.1016/B978-1-4557-0090-5.00052-5  0.015
2013 Purcell RH. Impact. The National Medical Journal of India. 26: 378-9. PMID 25141380  0.01
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