David Weinshenker, Ph.D. - Publications

Affiliations: 
Human Genetics Emory University, Atlanta, GA 
Area:
Norepinephrine

124 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lustberg DJ, Liu JQ, Iannitelli AF, Vanderhoof SO, Liles LC, McCann KE, Weinshenker D. Norepinephrine and dopamine contribute to distinct repetitive behaviors induced by novel odorant stress in male and female mice. Hormones and Behavior. 144: 105205. PMID 35660247 DOI: 10.1016/j.yhbeh.2022.105205  0.814
2022 Kelberman MA, Anderson CR, Chlan E, Rorabaugh JM, McCann KE, Weinshenker D. Consequences of Hyperphosphorylated Tau in the Locus Coeruleus on Behavior and Cognition in a Rat Model of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 35147547 DOI: 10.3233/JAD-215546  0.674
2021 Acosta MC, Tillage RP, Weinshenker D, Saltzman W. Acute inhibition of dopamine β-hydroxylase attenuates behavioral responses to pups in adult virgin California mice (Peromyscus californicus). Hormones and Behavior. 137: 105086. PMID 34808463 DOI: 10.1016/j.yhbeh.2021.105086  0.793
2021 Botz-Zapp CA, Foster SL, Pulley DM, Hempel B, Bi GH, Xi ZX, Newman AH, Weinshenker D, Manvich DF. Effects of the selective dopamine D receptor antagonist PG01037 on morphine-induced hyperactivity and antinociception in mice. Behavioural Brain Research. 113506. PMID 34352292 DOI: 10.1016/j.bbr.2021.113506  0.786
2021 Foster SL, Lustberg DJ, Harbin NH, Bramlett SN, Hepler JR, Weinshenker D. RGS14 modulates locomotor behavior and ERK signaling induced by environmental novelty and cocaine within discrete limbic structures. Psychopharmacology. PMID 34184126 DOI: 10.1007/s00213-021-05892-x  0.799
2021 Tillage RP, Foster SL, Lustberg D, Liles LC, McCann KE, Weinshenker D. Co-released norepinephrine and galanin act on different timescales to promote stress-induced anxiety-like behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 33911187 DOI: 10.1038/s41386-021-01011-8  0.787
2021 Foster SL, Galaj E, Karne SL, Ferré S, Weinshenker D. Cell-type specific expression and behavioral impact of galanin and GalR1 in the locus coeruleus during opioid withdrawal. Addiction Biology. e13037. PMID 33768673 DOI: 10.1111/adb.13037  0.591
2020 Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. 296: 100024. PMID 33410399 DOI: 10.1074/jbc.RA120.016009  0.751
2020 Squires KE, Gerber KJ, Tillman MC, Lustberg DJ, Montañez-Miranda C, Zhao M, Ramineni S, Scharer CD, Saha RN, Shu FJ, Schroeder JP, Ortlund EA, Weinshenker D, Dudek SM, Hepler JR. Human genetic variants disrupt RGS14 nuclear shuttling and regulation of LTP in hippocampal neurons. The Journal of Biological Chemistry. PMID 33154163 DOI: 10.1074/jbc.RA120.016009  0.751
2020 Poe GR, Foote S, Eschenko O, Johansen JP, Bouret S, Aston-Jones G, Harley CW, Manahan-Vaughan D, Weinshenker D, Valentino R, Berridge C, Chandler DJ, Waterhouse B, Sara SJ. Locus coeruleus: a new look at the blue spot. Nature Reviews. Neuroscience. PMID 32943779 DOI: 10.1038/S41583-020-0360-9  0.535
2020 Tillage RP, Wilson GE, Liles LC, Holmes PV, Weinshenker D. Chronic environmental or genetic elevation of galanin in noradrenergic neurons confers stress resilience in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868458 DOI: 10.1523/Jneurosci.0973-20.2020  0.796
2020 Butkovich LM, Houser MC, Chalermpalanupap T, Porter-Stransky KA, Iannitelli AF, Boles JS, Lloyd GM, Coomes AS, Eidson LN, De Sousa Rodrigues ME, Oliver DL, Kelly SD, Chang J, Bengoa-Vergniory N, Wade-Martins R, ... ... Weinshenker D, et al. Transgenic mice expressing human alpha-synuclein in noradrenergic neurons develop locus coeruleus pathology and non-motor features of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32868457 DOI: 10.1523/Jneurosci.1468-19.2020  0.767
2020 Lustberg D, Tillage RP, Bai Y, Pruitt M, Liles LC, Weinshenker D. Noradrenergic circuits in the forebrain control affective responses to novelty. Psychopharmacology. PMID 32821984 DOI: 10.1007/S00213-020-05615-8  0.79
2020 Lustberg D, Tillage RP, Bai Y, Pruitt M, Liles LC, Weinshenker D. Noradrenergic circuits in the forebrain control affective responses to novelty Psychopharmacology. PMID 32821984 DOI: 10.1007/s00213-020-05615-8  0.791
2020 Lustberg D, Iannitelli AF, Tillage RP, Pruitt M, Liles LC, Weinshenker D. Central norepinephrine transmission is required for stress-induced repetitive behavior in two rodent models of obsessive-compulsive disorder. Psychopharmacology. PMID 32313981 DOI: 10.1007/S00213-020-05512-0  0.783
2020 Lustberg D, Weinshenker D. Stressing the potential of guanfacine as a treatment for cocaine use disorder. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32152411 DOI: 10.1038/S41386-020-0649-4  0.76
2020 Tillage RP, Sciolino NR, Plummer NW, Lustberg D, Liles LC, Hsiang M, Powell JM, Smith KG, Jensen P, Weinshenker D. Elimination of galanin synthesis in noradrenergic neurons reduces galanin in select brain areas and promotes active coping behaviors. Brain Structure & Function. PMID 32065256 DOI: 10.1007/S00429-020-02035-4  0.781
2020 Branco RC, Burkett JP, Black CA, Winokur E, Elsworth W, Dhamsania RK, Lohr KM, Schroeder JP, Weinshenker D, Jovanovic T, Miller GW. Vesicular monoamine transporter 2 mediates fear behavior in mice. Genes, Brain, and Behavior. e12634. PMID 31898856 DOI: 10.1111/Gbb.12634  0.421
2020 Chandrasekharan BP, Foster SL, Saeedi B, Weinshenker D, Neish AS. Sa1099 LACTOBACILLUS RHAMNOSUS GG (LGG) -INDUCED ENTERIC NEURONAL DIFFERENTIATION ATTENUATES OPIOID-INDUCED CONSTIPATION Gastroenterology. 158: S-276. DOI: 10.1016/S0016-5085(20)31374-3  0.582
2019 Porter-Stransky KA, Petko AK, Karne SL, Liles LC, Urs NM, Caron MG, Paladini CA, Weinshenker D. Loss of β-arrestin2 in D2 cells alters neuronal excitability in the nucleus accumbens and behavioral responses to psychostimulants and opioids. Addiction Biology. e12823. PMID 31441201 DOI: 10.1111/Adb.12823  0.77
2019 Balu DT, Pantazopoulos H, Huang CCY, Muszynski K, Harvey TL, Uno Y, Rorabaugh JM, Galloway CR, Botz-Zapp C, Berretta S, Weinshenker D, Coyle JT. Neurotoxic astrocytes express the d-serine synthesizing enzyme, serine racemase, in Alzheimer's disease. Neurobiology of Disease. 104511. PMID 31212068 DOI: 10.1016/J.Nbd.2019.104511  0.767
2019 Rutkowski TP, Purcell RH, Pollak RM, Grewenow SM, Gafford GM, Malone T, Khan UA, Schroeder JP, Epstein MP, Bassell GJ, Warren ST, Weinshenker D, Caspary T, Mulle JG. Behavioral changes and growth deficits in a CRISPR engineered mouse model of the schizophrenia-associated 3q29 deletion. Molecular Psychiatry. PMID 30976085 DOI: 10.1038/S41380-019-0413-5  0.307
2019 Manvich DF, Petko AK, Branco RC, Foster SL, Porter-Stransky KA, Stout KA, Newman AH, Miller GW, Paladini CA, Weinshenker D. Selective D and D receptor antagonists oppositely modulate cocaine responses in mice via distinct postsynaptic mechanisms in nucleus accumbens. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 30879021 DOI: 10.1038/S41386-019-0371-2  0.801
2019 Foster S, Sciolino N, Jensen P, Weinshenker D. F205. Loss of Noradrenergic-Derived Galanin Enhances Opioid Reward and Reinforcement Biological Psychiatry. 85: S293. DOI: 10.1016/J.Biopsych.2019.03.742  0.761
2018 Porter-Stransky KA, Centanni SW, Karne SL, Odil LM, Fekir S, Wong JC, Jerome C, Mitchell HA, Escayg A, Pedersen NP, Winder DG, Mitrano DA, Weinshenker D. Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal. Biological Psychiatry. PMID 30269865 DOI: 10.1016/J.Biopsych.2018.07.027  0.788
2018 Rowson SA, Foster SL, Weinshenker D, Neigh GN. Locomotor sensitization to cocaine in adolescent and adult female Wistar rats. Behavioural Brain Research. PMID 29704596 DOI: 10.1016/J.Bbr.2018.04.035  0.587
2018 Manvich DF, Webster KA, Foster SL, Farrell MS, Ritchie JC, Porter JH, Weinshenker D. The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice. Scientific Reports. 8: 3840. PMID 29497149 DOI: 10.1038/S41598-018-22116-Z  0.795
2017 Chalermpalanupap T, Schroeder JP, Rorabaugh JM, Liles LC, Lah JJ, Levey AI, Weinshenker D. Locus coeruleus ablation exacerbates cognitive deficits, neuropathology, and lethality in P301S tau transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29133432 DOI: 10.1523/Jneurosci.1483-17.2017  0.317
2017 Di Ciano P, Manvich DF, Pushparaj A, Gappasov A, Hess EJ, Weinshenker D, Le Foll B. Effects of disulfiram on choice behavior in a rodent gambling task: association with catecholamine levels. Psychopharmacology. PMID 29085979 DOI: 10.1007/S00213-017-4744-0  0.771
2017 Rorabaugh JM, Chalermpalanupap T, Botz-Zapp CA, Fu VM, Lembeck NA, Cohen RM, Weinshenker D. Chemogenetic locus coeruleus activation restores reversal learning in a rat model of Alzheimer's disease. Brain : a Journal of Neurology. PMID 29053824 DOI: 10.1093/Brain/Awx232  0.324
2017 Christopher MA, Myrick DA, Barwick BG, Engstrom AK, Porter-Stransky KA, Boss JM, Weinshenker D, Levey AI, Katz DJ. LSD1 protects against hippocampal and cortical neurodegeneration. Nature Communications. 8: 805. PMID 28993646 DOI: 10.1038/S41467-017-00922-9  0.748
2017 Giddens MM, Wong JC, Schroeder JP, Farrow EG, Smith BM, Owino S, Soden SE, Meyer RC, Saunders C, LePichon JB, Weinshenker D, Escayg A, Hall RA. GPR37L1 modulates seizure susceptibility: Evidence from mouse studies and analyses of a human GPR37L1 variant. Neurobiology of Disease. PMID 28688853 DOI: 10.1016/J.Nbd.2017.07.006  0.324
2017 Schmidt KT, Schroeder JP, Foster SL, Squires K, Coleman BM, Pitts EG, Epstein MP, Weinshenker D. Norepinephrine regulates cocaine-primed reinstatement via α1-adrenergic receptors in the medial prefrontal cortex. Neuropharmacology. PMID 28392265 DOI: 10.1016/J.Neuropharm.2017.04.005  0.627
2017 Porter-Stransky KA, Weinshenker D. Arresting the Development of Addiction: The Role of β-Arrestin2 in Drug Abuse. The Journal of Pharmacology and Experimental Therapeutics. PMID 28302862 DOI: 10.1124/Jpet.117.240622  0.749
2017 Vadodaria KC, Yanpallewar SU, Vadhvani M, Toshniwal D, Liles LC, Rommelfanger KS, Weinshenker D, Vaidya VA. Noradrenergic regulation of plasticity marker expression in the adult rodent piriform cortex. Neuroscience Letters. PMID 28237805 DOI: 10.1016/J.Neulet.2017.02.060  0.701
2017 Porter JH, Manvich DF, Webster KA, Foster SL, Farrell MS, Weinshenker D. Behavioral and Pharmacokinetic Properties of the Putatively-Inert DREADD Ligand Clozapine-N-Oxide (CNO) in Rats and Mice The Faseb Journal. 31. DOI: 10.1096/Fasebj.31.1_Supplement.Lb594  0.583
2016 Gyoneva S, Swanger SA, Zhang J, Weinshenker D, Traynelis SF. Altered motility of plaque-associated microglia in a model of Alzheimer's disease. Neuroscience. PMID 27288150 DOI: 10.1016/J.Neuroscience.2016.05.061  0.535
2016 Cubells JF, Schroeder JP, Barrie ES, Manvich DF, Sadee W, Berg T, Mercer K, Stowe TA, Liles LC, Squires KE, Mezher A, Curtin P, Perdomo DL, Szot P, Weinshenker D. Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice. Plos One. 11: e0154864. PMID 27148966 DOI: 10.1371/Journal.Pone.0154864  0.79
2015 Weinshenker D, Holmes PV. Regulation of neurological and neuropsychiatric phenotypes by locus coeruleus-derived galanin. Brain Research. PMID 26607256 DOI: 10.1016/J.Brainres.2015.11.025  0.618
2015 Manvich DF, Stowe TA, Godfrey JR, Weinshenker D. A Method for Psychosocial Stress-Induced Reinstatement of Cocaine Seeking in Rats. Biological Psychiatry. PMID 26257242 DOI: 10.1016/J.Biopsych.2015.07.002  0.784
2015 Rose SJ, Yu XY, Heinzer AK, Harrast P, Fan X, Raike RS, Thompson VB, Pare JF, Weinshenker D, Smith Y, Jinnah HA, Hess EJ. A new knock-in mouse model of l-DOPA-responsive dystonia. Brain : a Journal of Neurology. 138: 2987-3002. PMID 26220941 DOI: 10.1093/Brain/Awv212  0.386
2015 Gokhale A, Vrailas-Mortimer A, Larimore J, Comstra HS, Zlatic SA, Werner E, Manvich DF, Iuvone PM, Weinshenker D, Faundez V. Neuronal copper homeostasis susceptibility by genetic defects in dysbindin, a schizophrenia susceptibility factor. Human Molecular Genetics. 24: 5512-23. PMID 26199316 DOI: 10.1093/Hmg/Ddv282  0.761
2015 Ogbonmwan YE, Schroeder JP, Holmes PV, Weinshenker D. The effects of post-extinction exercise on cocaine-primed and stress-induced reinstatement of cocaine seeking in rats. Psychopharmacology. 232: 1395-403. PMID 25358851 DOI: 10.1007/S00213-014-3778-9  0.598
2015 Sciolino NR, Smith JM, Stranahan AM, Freeman KG, Edwards GL, Weinshenker D, Holmes PV. Galanin mediates features of neural and behavioral stress resilience afforded by exercise. Neuropharmacology. 89: 255-64. PMID 25301278 DOI: 10.1016/J.Neuropharm.2014.09.029  0.789
2015 Liu X, Ye K, Weinshenker D. Norepinephrine Protects against Amyloid-β Toxicity via TrkB. Journal of Alzheimer's Disease : Jad. 44: 251-60. PMID 25208620 DOI: 10.3233/Jad-141062  0.331
2015 Ogbonmwan YE, Sciolino NR, Groves-Chapman JL, Freeman KG, Schroeder JP, Edwards GL, Holmes PV, Weinshenker D. The galanin receptor agonist, galnon, attenuates cocaine-induced reinstatement and dopamine overflow in the frontal cortex. Addiction Biology. 20: 701-13. PMID 25053279 DOI: 10.1111/Adb.12166  0.796
2014 Barrie ES, Weinshenker D, Verma A, Pendergrass SA, Lange LA, Ritchie MD, Wilson JG, Kuivaniemi H, Tromp G, Carey DJ, Gerhard GS, Brilliant MH, Hebbring SJ, Cubells JF, Pinsonneault JK, et al. Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circulation Research. 115: 1017-25. PMID 25326128 DOI: 10.1161/Circresaha.116.304398  0.332
2014 Gaval-Cruz M, Goertz RB, Puttick DJ, Bowles DE, Meyer RC, Hall RA, Ko D, Paladini CA, Weinshenker D. Chronic loss of noradrenergic tone produces β-arrestin2-mediated cocaine hypersensitivity and alters cellular D2 responses in the nucleus accumbens. Addiction Biology. PMID 25123018 DOI: 10.1111/Adb.12174  0.403
2014 Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8845-54. PMID 24966384 DOI: 10.1523/Jneurosci.4027-13.2014  0.338
2014 Cooper DA, Kimmel HL, Manvich DF, Schmidt KT, Weinshenker D, Howell LL. Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys. The Journal of Pharmacology and Experimental Therapeutics. 350: 144-52. PMID 24817036 DOI: 10.1124/Jpet.113.212357  0.802
2014 Schmidt KT, Weinshenker D. Adrenaline rush: the role of adrenergic receptors in stimulant-induced behaviors. Molecular Pharmacology. 85: 640-50. PMID 24499709 DOI: 10.1124/Mol.113.090118  0.398
2014 Mitrano DA, Pare JF, Smith Y, Weinshenker D. D1-dopamine and α1-adrenergic receptors co-localize in dendrites of the rat prefrontal cortex. Neuroscience. 258: 90-100. PMID 24231738 DOI: 10.1016/J.Neuroscience.2013.11.002  0.349
2014 Schank JR, King CE, Sun H, Cheng K, Rice KC, Heilig M, Weinshenker D, Schroeder JP. The role of the neurokinin-1 receptor in stress-induced reinstatement of alcohol and cocaine seeking. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 1093-101. PMID 24173499 DOI: 10.1038/Npp.2013.309  0.709
2014 Zhang Z, Liu X, Schroeder JP, Chan CB, Song M, Yu SP, Weinshenker D, Ye K. 7,8-dihydroxyflavone prevents synaptic loss and memory deficits in a mouse model of Alzheimer's disease. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 638-50. PMID 24022672 DOI: 10.1038/Npp.2013.243  0.303
2013 Manvich DF, DePoy LM, Weinshenker D. Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats. The Journal of Pharmacology and Experimental Therapeutics. 347: 564-73. PMID 24068832 DOI: 10.1124/Jpet.113.207746  0.781
2013 Epps SA, Kahn AB, Holmes PV, Boss-Williams KA, Weiss JM, Weinshenker D. Antidepressant and anticonvulsant effects of exercise in a rat model of epilepsy and depression comorbidity. Epilepsy & Behavior : E&B. 29: 47-52. PMID 23933912 DOI: 10.1016/J.Yebeh.2013.06.023  0.58
2013 Purcell RH, Papale LA, Makinson CD, Sawyer NT, Schroeder JP, Escayg A, Weinshenker D. Effects of an epilepsy-causing mutation in the SCN1A sodium channel gene on cocaine-induced seizure susceptibility in mice. Psychopharmacology. 228: 263-70. PMID 23494229 DOI: 10.1007/S00213-013-3034-8  0.381
2013 Schroeder JP, Epps SA, Grice TW, Weinshenker D. The selective dopamine β-hydroxylase inhibitor nepicastat attenuates multiple aspects of cocaine-seeking behavior. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 1032-8. PMID 23303068 DOI: 10.1038/Npp.2012.267  0.359
2013 Epps SA, Weinshenker D. Rhythm and blues: animal models of epilepsy and depression comorbidity. Biochemical Pharmacology. 85: 135-46. PMID 22940575 DOI: 10.1016/J.Bcp.2012.08.016  0.324
2013 Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biological Psychiatry. 73: 454-63. PMID 22883210 DOI: 10.1016/J.Biopsych.2012.06.013  0.706
2012 Gaval-Cruz M, Liles LC, Iuvone PM, Weinshenker D. Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice. Plos One. 7: e50583. PMID 23209785 DOI: 10.1371/Journal.Pone.0050583  0.389
2012 Lin SJ, Epps SA, West CH, Boss-Williams KA, Weiss JM, Weinshenker D. Operant psychostimulant self-administration in a rat model of depression. Pharmacology, Biochemistry, and Behavior. 103: 380-5. PMID 23010383 DOI: 10.1016/J.Pbb.2012.09.008  0.335
2012 Epps SA, Tabb KD, Lin SJ, Kahn AB, Javors MA, Boss-Williams KA, Weiss JM, Weinshenker D. Seizure susceptibility and epileptogenesis in a rat model of epilepsy and depression co-morbidity. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2756-63. PMID 22871911 DOI: 10.1038/Npp.2012.141  0.777
2012 Mitrano DA, Schroeder JP, Smith Y, Cortright JJ, Bubula N, Vezina P, Weinshenker D. α-1 Adrenergic receptors are localized on presynaptic elements in the nucleus accumbens and regulate mesolimbic dopamine transmission. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2161-72. PMID 22588352 DOI: 10.1038/Npp.2012.68  0.398
2012 Rovin ML, Boss-Williams KA, Alisch RS, Ritchie JC, Weinshenker D, West CH, Weiss JM. Influence of chronic administration of antidepressant drugs on mRNA for galanin, galanin receptors, and tyrosine hydroxylase in catecholaminergic and serotonergic cell-body regions in rat brain. Neuropeptides. 46: 81-91. PMID 22317959 DOI: 10.1016/J.Npep.2012.01.001  0.33
2012 Epps⁎ S, Tabb K, Williams K, Weiss J, Weinshenker D. Genetic and behavioural characterization of a rodent model of depression and epilepsy co-morbidity Epilepsy & Behavior. 24: 182-183. DOI: 10.1016/J.Yebeh.2011.04.014  0.759
2011 Keebaugh AC, Mitchell HA, Gaval-Cruz M, Freeman KG, Edwards GL, Weinshenker D, Thomas JW. PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. Plos One. 6: e22381. PMID 21818316 DOI: 10.1371/Journal.Pone.0022381  0.715
2010 Lee SE, Simons SB, Heldt SA, Zhao M, Schroeder JP, Vellano CP, Cowan DP, Ramineni S, Yates CK, Feng Y, Smith Y, Sweatt JD, Weinshenker D, Ressler KJ, Dudek SM, et al. RGS14 is a natural suppressor of both synaptic plasticity in CA2 neurons and hippocampal-based learning and memory. Proceedings of the National Academy of Sciences of the United States of America. 107: 16994-8. PMID 20837545 DOI: 10.1073/Pnas.1005362107  0.595
2010 Weinshenker D. Cocaine sobers up. Nature Medicine. 16: 969-70. PMID 20823878 DOI: 10.1038/Nm0910-969  0.35
2010 Schroeder JP, Cooper DA, Schank JR, Lyle MA, Gaval-Cruz M, Ogbonmwan YE, Pozdeyev N, Freeman KG, Iuvone PM, Edwards GL, Holmes PV, Weinshenker D. Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 2440-9. PMID 20736996 DOI: 10.1038/Npp.2010.127  0.775
2010 Skinbjerg M, Seneca N, Liow JS, Hong J, Weinshenker D, Pike VW, Halldin C, Sibley DR, Innis RB. Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding. Synapse (New York, N.Y.). 64: 699-703. PMID 20336622 DOI: 10.1002/Syn.20781  0.338
2010 Yanpallewar SU, Fernandes K, Marathe SV, Vadodaria KC, Jhaveri D, Rommelfanger K, Ladiwala U, Jha S, Muthig V, Hein L, Bartlett P, Weinshenker D, Vaidya VA. Alpha2-adrenoceptor blockade accelerates the neurogenic, neurotrophic, and behavioral effects of chronic antidepressant treatment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1096-109. PMID 20089918 DOI: 10.1523/Jneurosci.2309-09.2010  0.698
2010 Mitchell HA, Weinshenker D. Good night and good luck: norepinephrine in sleep pharmacology. Biochemical Pharmacology. 79: 801-9. PMID 19833104 DOI: 10.1016/J.Bcp.2009.10.004  0.677
2009 Gaval-Cruz M, Weinshenker D. mechanisms of disulfiram-induced cocaine abstinence: antabuse and cocaine relapse. Molecular Interventions. 9: 175-87. PMID 19720750 DOI: 10.1124/Mi.9.4.6  0.313
2009 Taylor TN, Caudle WM, Shepherd KR, Noorian A, Jackson CR, Iuvone PM, Weinshenker D, Greene JG, Miller GW. Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 8103-13. PMID 19553450 DOI: 10.1523/Jneurosci.1495-09.2009  0.354
2009 Jang SW, Liu X, Chan CB, Weinshenker D, Hall RA, Xiao G, Ye K. Amitriptyline is a TrkA and TrkB receptor agonist that promotes TrkA/TrkB heterodimerization and has potent neurotrophic activity. Chemistry & Biology. 16: 644-56. PMID 19549602 DOI: 10.1016/J.Chembiol.2009.05.010  0.323
2009 Gilsbach R, Röser C, Beetz N, Brede M, Hadamek K, Haubold M, Leemhuis J, Philipp M, Schneider J, Urbanski M, Szabo B, Weinshenker D, Hein L. Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells. Molecular Pharmacology. 75: 1160-70. PMID 19251826 DOI: 10.1124/Mol.109.054544  0.309
2009 Xiao Z, Deng PY, Rojanathammanee L, Yang C, Grisanti L, Permpoonputtana K, Weinshenker D, Doze VA, Porter JE, Lei S. Noradrenergic depression of neuronal excitability in the entorhinal cortex via activation of TREK-2 K+ channels. The Journal of Biological Chemistry. 284: 10980-91. PMID 19244246 DOI: 10.1074/Jbc.M806760200  0.323
2009 Rommelfanger KS, Mitrano DA, Smith Y, Weinshenker D. Light and electron microscopic localization of alpha-1 adrenergic receptor immunoreactivity in the rat striatum and ventral midbrain. Neuroscience. 158: 1530-40. PMID 19068224 DOI: 10.1016/J.Neuroscience.2008.11.019  0.692
2009 Mitchell HA, Bogenpohl JW, Liles LC, Epstein MP, Bozyczko-Coyne D, Williams M, Weinshenker D. Corrigendum to "Behavioral responses of dopamine β-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action" (DOI:10.1016/j.pbb.2008.07.014) Pharmacology Biochemistry and Behavior. 92: 197. DOI: 10.1016/j.pbb.2008.12.001  0.714
2008 Swoap SJ, Weinshenker D. Norepinephrine controls both torpor initiation and emergence via distinct mechanisms in the mouse. Plos One. 3: e4038. PMID 19107190 DOI: 10.1371/Journal.Pone.0004038  0.368
2008 Weinshenker D, Warren ST. Neuroscience: fragile dopamine. Nature. 455: 607-8. PMID 18833269 DOI: 10.1038/455607A  0.311
2008 Mitchell HA, Bogenpohl JW, Liles LC, Epstein MP, Bozyczko-Coyne D, Williams M, Weinshenker D. Behavioral responses of dopamine beta-hydroxylase knockout mice to modafinil suggest a dual noradrenergic-dopaminergic mechanism of action. Pharmacology, Biochemistry, and Behavior. 91: 217-22. PMID 18703079 DOI: 10.1016/J.Pbb.2008.07.014  0.746
2008 Lin Y, Quartermain D, Dunn AJ, Weinshenker D, Stone EA. Possible dopaminergic stimulation of locus coeruleus alpha1-adrenoceptors involved in behavioral activation. Synapse (New York, N.Y.). 62: 516-23. PMID 18435418 DOI: 10.1002/Syn.20517  0.371
2008 Gaval-Cruz M, Schroeder JP, Liles LC, Javors MA, Weinshenker D. Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures. Pharmacology, Biochemistry, and Behavior. 89: 556-62. PMID 18329701 DOI: 10.1016/J.Pbb.2008.02.009  0.382
2008 Schank JR, Liles LC, Weinshenker D. Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety. Biological Psychiatry. 63: 1007-12. PMID 18083142 DOI: 10.1016/J.Biopsych.2007.10.018  0.74
2008 Weinshenker D, Ferrucci M, Busceti CL, Biagioni F, Lazzeri G, Liles LC, Lenzi P, Pasquali L, Murri L, Paparelli A, Fornai F. Genetic or pharmacological blockade of noradrenaline synthesis enhances the neurochemical, behavioral, and neurotoxic effects of methamphetamine. Journal of Neurochemistry. 105: 471-83. PMID 18042179 DOI: 10.1111/J.1471-4159.2007.05145.X  0.412
2007 Rommelfanger KS, Edwards GL, Freeman KG, Liles LC, Miller GW, Weinshenker D. Norepinephrine loss produces more profound motor deficits than MPTP treatment in mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 13804-9. PMID 17702867 DOI: 10.1073/Pnas.0702753104  0.711
2007 Rommelfanger KS, Weinshenker D. Norepinephrine: The redheaded stepchild of Parkinson's disease. Biochemical Pharmacology. 74: 177-90. PMID 17416354 DOI: 10.1016/J.Bcp.2007.01.036  0.683
2007 Tabb K, Boss-Williams KA, Weiss JM, Weinshenker D. Rats bred for susceptibility to depression-like phenotypes have higher kainic acid-induced seizure mortality than their depression-resistant counterparts. Epilepsy Research. 74: 140-6. PMID 17400428 DOI: 10.1016/J.Eplepsyres.2007.02.006  0.772
2007 Weinshenker D, Schroeder JP. There and back again: a tale of norepinephrine and drug addiction. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 32: 1433-51. PMID 17164822 DOI: 10.1038/Sj.Npp.1301263  0.389
2007 Paladini CA, Beckstead MJ, Weinshenker D. Electrophysiological properties of catecholaminergic neurons in the norepinephrine-deficient mouse. Neuroscience. 144: 1067-74. PMID 17156935 DOI: 10.1016/J.Neuroscience.2006.10.032  0.39
2007 Sowden GL, Drucker DJ, Weinshenker D, Swoap SJ. Oxyntomodulin increases intrinsic heart rate in mice independent of the glucagon-like peptide-1 receptor. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 292: R962-70. PMID 17038440 DOI: 10.1152/Ajpregu.00405.2006  0.341
2006 Mitchell HA, Ahern TH, Liles LC, Javors MA, Weinshenker D. The effects of norepinephrine transporter inactivation on locomotor activity in mice. Biological Psychiatry. 60: 1046-52. PMID 16893531 DOI: 10.1016/J.Biopsych.2006.03.057  0.709
2006 Sanders JD, Szot P, Weinshenker D, Happe HK, Bylund DB, Murrin LC. Analysis of brain adrenergic receptors in dopamine-beta-hydroxylase knockout mice. Brain Research. 1109: 45-53. PMID 16854392 DOI: 10.1016/J.Brainres.2006.06.033  0.301
2006 Reiner DJ, Weinshenker D, Tian H, Thomas JH, Nishiwaki K, Miwa J, Gruninger T, Leboeuf B, Garcia LR. Behavioral genetics of caenorhabditis elegans unc-103-encoded erg-like K(+) channel. Journal of Neurogenetics. 20: 41-66. PMID 16807195 DOI: 10.1080/01677060600788826  0.465
2006 Seeman P, Schwarz J, Chen JF, Szechtman H, Perreault M, McKnight GS, Roder JC, Quirion R, Boksa P, Srivastava LK, Yanai K, Weinshenker D, Sumiyoshi T. Psychosis pathways converge via D2high dopamine receptors. Synapse (New York, N.Y.). 60: 319-46. PMID 16786561 DOI: 10.1002/Syn.20303  0.375
2006 Olson VG, Heusner CL, Bland RJ, During MJ, Weinshenker D, Palmiter RD. Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science (New York, N.Y.). 311: 1017-20. PMID 16484499 DOI: 10.1126/Science.1119311  0.802
2006 Swoap SJ, Gutilla MJ, Liles LC, Smith RO, Weinshenker D. The full expression of fasting-induced torpor requires beta 3-adrenergic receptor signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 241-5. PMID 16399693 DOI: 10.1523/Jneurosci.3721-05.2006  0.33
2006 Schank JR, Ventura R, Puglisi-Allegra S, Alcaro A, Cole CD, Liles LC, Seeman P, Weinshenker D. Dopamine beta-hydroxylase knockout mice have alterations in dopamine signaling and are hypersensitive to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2221-30. PMID 16395294 DOI: 10.1038/Sj.Npp.1301000  0.754
2006 Martillotti J, Weinshenker D, Liles LC, Eagles DA. A ketogenic diet and knockout of the norepinephrine transporter both reduce seizure severity in mice. Epilepsy Research. 68: 207-11. PMID 16356685 DOI: 10.1016/J.Eplepsyres.2005.11.002  0.334
2006 Ahern TH, Javors MA, Eagles DA, Martillotti J, Mitchell HA, Liles LC, Weinshenker D. The effects of chronic norepinephrine transporter inactivation on seizure susceptibility in mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 730-8. PMID 16052243 DOI: 10.1038/Sj.Npp.1300847  0.701
2005 Bourdélat-Parks BN, Anderson GM, Donaldson ZR, Weiss JM, Bonsall RW, Emery MS, Liles LC, Weinshenker D. Effects of dopamine beta-hydroxylase genotype and disulfiram inhibition on catecholamine homeostasis in mice. Psychopharmacology. 183: 72-80. PMID 16163519 DOI: 10.1007/S00213-005-0139-8  0.34
2005 Schank JR, Liles LC, Weinshenker D. Reduced anticonvulsant efficacy of valproic acid in dopamine beta-hydroxylase knockout mice. Epilepsy Research. 65: 23-31. PMID 15955669 DOI: 10.1016/J.Eplepsyres.2005.03.010  0.719
2005 Marino MD, Bourdélat-Parks BN, Cameron Liles L, Weinshenker D. Genetic reduction of noradrenergic function alters social memory and reduces aggression in mice. Behavioural Brain Research. 161: 197-203. PMID 15922045 DOI: 10.1016/J.Bbr.2005.02.005  0.348
2005 Gottsch ML, Zeng H, Hohmann JG, Weinshenker D, Clifton DK, Steiner RA. Phenotypic analysis of mice deficient in the type 2 galanin receptor (GALR2). Molecular and Cellular Biology. 25: 4804-11. PMID 15899880 DOI: 10.1128/Mcb.25.11.4804-4811.2005  0.352
2005 Seeman P, Weinshenker D, Quirion R, Srivastava LK, Bhardwaj SK, Grandy DK, Premont RT, Sotnikova TD, Boksa P, El-Ghundi M, O'dowd BF, George SR, Perreault ML, Männistö PT, Robinson S, et al. Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proceedings of the National Academy of Sciences of the United States of America. 102: 3513-8. PMID 15716360 DOI: 10.1073/Pnas.0409766102  0.524
2004 Rommelfanger KS, Weinshenker D, Miller GW. Reduced MPTP toxicity in noradrenaline transporter knockout mice. Journal of Neurochemistry. 91: 1116-24. PMID 15569255 DOI: 10.1111/J.1471-4159.2004.02785.X  0.729
2004 Tabb K, Szot P, White SS, Liles LC, Weinshenker D. The ketogenic diet does not alter brain expression of orexigenic neuropeptides. Epilepsy Research. 62: 35-9. PMID 15519130 DOI: 10.1016/J.Eplepsyres.2004.08.002  0.763
2004 Szot P, Lester M, Laughlin ML, Palmiter RD, Liles LC, Weinshenker D. The anticonvulsant and proconvulsant effects of alpha2-adrenoreceptor agonists are mediated by distinct populations of alpha2A-adrenoreceptors. Neuroscience. 126: 795-803. PMID 15183527 DOI: 10.1016/J.Neuroscience.2004.04.030  0.516
2004 Hohmann JG, Teklemichael DN, Weinshenker D, Wynick D, Clifton DK, Steiner RA. Obesity and endocrine dysfunction in mice with deletions of both neuropeptide Y and galanin. Molecular and Cellular Biology. 24: 2978-85. PMID 15024085 DOI: 10.1128/Mcb.24.7.2978-2985.2004  0.313
2004 Swoap SJ, Weinshenker D, Palmiter RD, Garber G. Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R108-13. PMID 12969876 DOI: 10.1152/Ajpregu.00405.2003  0.502
2002 Weinshenker D, Miller NS, Blizinsky K, Laughlin ML, Palmiter RD. Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proceedings of the National Academy of Sciences of the United States of America. 99: 13873-7. PMID 12370425 DOI: 10.1073/Pnas.212519999  0.585
2002 Weinshenker D, White SS, Javors MA, Palmiter RD, Szot P. Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. Brain Research. 946: 239-46. PMID 12137927 DOI: 10.1016/S0006-8993(02)02889-5  0.545
2002 Weinshenker D, Szot P. The role of catecholamines in seizure susceptibility: new results using genetically engineered mice. Pharmacology & Therapeutics. 94: 213-33. PMID 12113799 DOI: 10.1016/S0163-7258(02)00218-8  0.36
2002 Jasmin L, Tien D, Weinshenker D, Palmiter RD, Green PG, Janni G, Ohara PT. The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proceedings of the National Academy of Sciences of the United States of America. 99: 1029-34. PMID 11805341 DOI: 10.1073/Pnas.012598599  0.515
2001 Weinshenker D, Szot P, Miller NS, Rust NC, Hohmann JG, Pyati U, White SS, Palmiter RD. Genetic comparison of seizure control by norepinephrine and neuropeptide Y. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 7764-9. PMID 11567066 DOI: 10.1523/Jneurosci.21-19-07764.2001  0.532
2001 Szot P, Weinshenker D, Rho JM, Storey TW, Schwartzkroin PA. Norepinephrine is required for the anticonvulsant effect of the ketogenic diet. Brain Research. Developmental Brain Research. 129: 211-4. PMID 11506865 DOI: 10.1016/S0165-3806(01)00213-9  0.344
2001 Weinshenker D, Szot P, Miller NS, Palmiter RD. Alpha(1) and beta(2) adrenoreceptor agonists inhibit pentylenetetrazole-induced seizures in mice lacking norepinephrine. The Journal of Pharmacology and Experimental Therapeutics. 298: 1042-8. PMID 11504801  0.442
2000 Weinshenker D, Rust NC, Miller NS, Palmiter RD. Ethanol-associated behaviors of mice lacking norepinephrine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 3157-64. PMID 10777779 DOI: 10.1523/Jneurosci.20-09-03157.2000  0.485
1999 Szot P, Weinshenker D, White SS, Robbins CA, Rust NC, Schwartzkroin PA, Palmiter RD. Norepinephrine-deficient mice have increased susceptibility to seizure-inducing stimuli. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 10985-92. PMID 10594079 DOI: 10.1523/Jneurosci.19-24-10985.1999  0.517
1999 Weinshenker D, Wei A, Salkoff L, Thomas JH. Block of an ether-a-go-go-like K(+) channel by imipramine rescues egl-2 excitation defects in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 9831-40. PMID 10559392 DOI: 10.1523/Jneurosci.19-22-09831.1999  0.43
1995 Reiner DJ, Weinshenker D, Thomas JH. Analysis of dominant mutations affecting muscle excitation in Caenorhabditis elegans. Genetics. 141: 961-76. PMID 8582640  0.336
1995 Weinshenker D, Garriga G, Thomas JH. Genetic and pharmacological analysis of neurotransmitters controlling egg laying in C. elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6975-85. PMID 7472454 DOI: 10.1523/Jneurosci.15-10-06975.1995  0.456
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