Edward Giniger - Publications

Affiliations: 
NINDS National Institutes of Health, Bethesda, MD 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Wincovitch S, Giniger E. Abl signaling directs growth of a pioneer axon in by shaping the intrinsic fluctuations of actin. Molecular Biology of the Cell. mbcE19100564. PMID 31967946 DOI: 10.1091/mbc.E19-10-0564  0.96
2020 Clarke A, McQueen PG, Fang HY, Kannan R, Wang V, McCreedy E, Buckley T, Johannessen EM, Wincovitch S, Giniger E. Dynamic morphogenesis of a pioneer axon in and its regulation by Abl tyrosine kinase. Molecular Biology of the Cell. mbcE19100563. PMID 31967935 DOI: 10.1091/mbc.E19-10-0563  0.96
2019 Spurrier J, Shukla AK, Buckley T, Smith-Trunova S, Kuzina I, Gu Q, Giniger E. Expression of a Fragment of Ankyrin 2 Disrupts the Structure of the Axon Initial Segment and Causes Axonal Degeneration in Drosophila. Molecular Neurobiology. PMID 30666562 DOI: 10.1007/s12035-019-1477-6  0.4
2019 Shukla AK, Spurrier J, Kuzina I, Giniger E. Hyperactive Innate Immunity Causes Degeneration of Dopamine Neurons upon Altering Activity of Cdk5. Cell Reports. 26: 131-144.e4. PMID 30605670 DOI: 10.1016/j.celrep.2018.12.025  0.4
2018 Kannan R, Cox E, Wang L, Kuzina I, Gu Q, Giniger E. Tyrosine phosphorylation and proteolytic cleavage of Notch are required for non-canonical Notch/Abl signaling in Drosophila axon guidance. Development (Cambridge, England). 145. PMID 29343637 DOI: 10.1242/dev.151548  0.96
2017 Kannan R, Giniger E. New perspectives on the roles of Abl tyrosine kinase in axon patterning. Fly. 0. PMID 28481649 DOI: 10.1080/19336934.2017.1327106  0.96
2017 Kannan R, Song JK, Karpova T, Clarke A, Shivalkar M, Wang B, Kotlyanskaya L, Kuzina I, Gu Q, Giniger E. The Abl pathway bifurcates to balance Enabled and Rac signaling in axon patterning in Drosophila. Development (Cambridge, England). PMID 28087633 DOI: 10.1242/dev.143776  0.96
2015 Smith-Trunova S, Prithviraj R, Spurrier J, Kuzina I, Gu Q, Giniger E. Cdk5 regulates developmental remodeling of mushroom body neurons in Drosophila. Developmental Dynamics : An Official Publication of the American Association of Anatomists. PMID 26394609 DOI: 10.1002/dvdy.24350  1
2014 Kannan R, Kuzina I, Wincovitch S, Nowotarski SH, Giniger E. The Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neurons. Molecular Biology of the Cell. 25: 2993-3005. PMID 25103244 DOI: 10.1091/mbc.E14-02-0729  1
2014 Ferreira T, Ou Y, Li S, Giniger E, van Meyel DJ. Dendrite architecture organized by transcriptional control of the F-actin nucleator Spire. Development (Cambridge, England). 141: 650-60. PMID 24449841 DOI: 10.1242/dev.099655  1
2013 Kotlyanskaya L, McLinden KA, Giniger E. Of proneurotrophins and their antineurotrophic effects. Science Signaling. 6: pe6. PMID 23405011 DOI: 10.1126/scisignal.2003824  1
2012 McLinden KA, Trunova S, Giniger E. At the Fulcrum in Health and Disease: Cdk5 and the Balancing Acts of Neuronal Structure and Physiology. Brain Disorders & Therapy. 2012: 001. PMID 25364642 DOI: 10.4172/2168-975X.S1-001  0.92
2012 Prithviraj R, Trunova S, Giniger E. Ex vivo culturing of whole, developing Drosophila brains. Journal of Visualized Experiments : Jove. PMID 22871650 DOI: 10.3791/4270  0.64
2012 Giniger E. Notch signaling and neural connectivity. Current Opinion in Genetics & Development. 22: 339-46. PMID 22608692 DOI: 10.1016/j.gde.2012.04.003  1
2012 Shivalkar M, Giniger E. Control of dendritic morphogenesis by Trio in Drosophila melanogaster. Plos One. 7: e33737. PMID 22438988 DOI: 10.1371/journal.pone.0033737  1
2012 Trunova S, Giniger E. Absence of the Cdk5 activator p35 causes adult-onset neurodegeneration in the central brain of Drosophila. Disease Models & Mechanisms. 5: 210-9. PMID 22228754 DOI: 10.1242/dmm.008847  1
2011 Gates MA, Kannan R, Giniger E. A genome-wide analysis reveals that the Drosophila transcription factor Lola promotes axon growth in part by suppressing expression of the actin nucleation factor Spire. Neural Development. 6: 37. PMID 22129300 DOI: 10.1186/1749-8104-6-37  1
2011 Trunova S, Baek B, Giniger E. Cdk5 regulates the size of an axon initial segment-like compartment in mushroom body neurons of the Drosophila central brain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10451-62. PMID 21775591 DOI: 10.1523/JNEUROSCI.0117-11.2011  1
2011 Kuzina I, Song JK, Giniger E. How Notch establishes longitudinal axon connections between successive segments of the Drosophila CNS. Development (Cambridge, England). 138: 1839-49. PMID 21447553 DOI: 10.1242/dev.062471  1
2011 Song JK, Giniger E. Noncanonical Notch function in motor axon guidance is mediated by Rac GTPase and the GEF1 domain of Trio. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 324-32. PMID 21246649 DOI: 10.1002/dvdy.22525  1
2010 Song JK, Kannan R, Merdes G, Singh J, Mlodzik M, Giniger E. Disabled is a bona fide component of the Abl signaling network. Development (Cambridge, England). 137: 3719-27. PMID 20940230 DOI: 10.1242/dev.050948  1
2008 Song JK, Giniger E, Desai CJ. The receptor protein tyrosine phosphatase PTP69D antagonizes Abl tyrosine kinase to guide axons in Drosophila. Mechanisms of Development. 125: 247-56. PMID 18160268 DOI: 10.1016/j.mod.2007.11.005  1
2008 Le Gall M, De Mattei C, Giniger E. Molecular separation of two signaling pathways for the receptor, Notch. Developmental Biology. 313: 556-67. PMID 18062953 DOI: 10.1016/j.ydbio.2007.10.030  1
2007 Spletter ML, Liu J, Liu J, Su H, Giniger E, Komiyama T, Quake S, Luo L. Lola regulates Drosophila olfactory projection neuron identity and targeting specificity. Neural Development. 2: 14. PMID 17634136 DOI: 10.1186/1749-8104-2-14  1
2007 Connell-Crowley L, Vo D, Luke L, Giniger E. Drosophila lacking the Cdk5 activator, p35, display defective axon guidance, age-dependent behavioral deficits and reduced lifespan. Mechanisms of Development. 124: 341-9. PMID 17368005 DOI: 10.1016/j.mod.2007.02.002  1
2004 Le Gall M, Giniger E. Identification of two binding regions for the suppressor of hairless protein within the intracellular domain of Drosophila notch. The Journal of Biological Chemistry. 279: 29418-26. PMID 15123610 DOI: 10.1074/jbc.M404589200  1
2003 Horiuchi T, Giniger E, Aigaki T. Alternative trans-splicing of constant and variable exons of a Drosophila axon guidance gene, lola. Genes & Development. 17: 2496-501. PMID 14522953 DOI: 10.1101/gad.1137303  1
2003 Goeke S, Greene EA, Grant PK, Gates MA, Crowner D, Aigaki T, Giniger E. Alternative splicing of lola generates 19 transcription factors controlling axon guidance in Drosophila. Nature Neuroscience. 6: 917-24. PMID 12897787 DOI: 10.1038/nn1105  1
2003 Crowner D, Le Gall M, Gates MA, Giniger E. Notch steers Drosophila ISNb motor axons by regulating the Abl signaling pathway. Current Biology : Cb. 13: 967-72. PMID 12781136 DOI: 10.1016/S0960-9822(03)00325-7  1
2002 Giniger E. How do Rho family GTPases direct axon growth and guidance? A proposal relating signaling pathways to growth cone mechanics. Differentiation; Research in Biological Diversity. 70: 385-96. PMID 12366376 DOI: 10.1046/j.1432-0436.2002.700801.x  1
2002 Crowner D, Madden K, Goeke S, Giniger E. Lola regulates midline crossing of CNS axons in Drosophila. Development (Cambridge, England). 129: 1317-25. PMID 11880341  1
2000 Bothwell M, Giniger E. Alzheimer's disease: neurodevelopment converges with neurodegeneration. Cell. 102: 271-3. PMID 10975517  1
2000 Hiramoto M, Hiromi Y, Giniger E, Hotta Y. The Drosophila Netrin receptor Frazzled guides axons by controlling Netrin distribution. Nature. 406: 886-9. PMID 10972289 DOI: 10.1038/35022571  1
2000 Connell-Crowley L, Le Gall M, Vo DJ, Giniger E. The cyclin-dependent kinase Cdk5 controls multiple aspects of axon patterning in vivo. Current Biology : Cb. 10: 599-602. PMID 10837225 DOI: 10.1016/S0960-9822(00)00487-5  1
1999 Madden K, Crowner D, Giniger E. LOLA has the properties of a master regulator of axon-target interaction for SNb motor axons of Drosophila. Developmental Biology. 213: 301-13. PMID 10479449 DOI: 10.1006/dbio.1999.9399  1
1998 Fuerstenberg S, Giniger E. Multiple roles for notch in Drosophila myogenesis. Developmental Biology. 201: 66-77. PMID 9733574 DOI: 10.1006/dbio.1998.8944  1
1998 Giniger E. A role for Abl in Notch signaling. Neuron. 20: 667-81. PMID 9581760 DOI: 10.1016/S0896-6273(00)81007-7  1
1996 Larkin MK, Holder K, Yost C, Giniger E, Ruohola-Baker H. Expression of constitutively active Notch arrests follicle cells at a precursor stage during Drosophila oogenesis and disrupts the anterior-posterior axis of the oocyte. Development (Cambridge, England). 122: 3639-50. PMID 8951079  1
1994 Giniger E, Tietje K, Jan LY, Jan YN. lola encodes a putative transcription factor required for axon growth and guidance in Drosophila. Development (Cambridge, England). 120: 1385-98. PMID 8050351  1
1994 Clark I, Giniger E, Ruohola-Baker H, Jan LY, Jan YN. Transient posterior localization of a kinesin fusion protein reflects anteroposterior polarity of the Drosophila oocyte. Current Biology : Cb. 4: 289-300. PMID 7922338 DOI: 10.1016/S0960-9822(00)00068-3  1
1993 Giniger E, Wells W, Jan LY, Jan YN. Tracing neurons with a kinesin-β-galactosidase fusion protein. Roux's Archives of Developmental Biology : the Official Organ of the Edbo. 202: 112-122. PMID 28305652 DOI: 10.1007/BF00636536  0.96
1993 Giniger E, Jan LY, Jan YN. Specifying the path of the intersegmental nerve of the Drosophila embryo: a role for Delta and Notch. Development (Cambridge, England). 117: 431-40. PMID 8330518  1
1993 Giniger E, Wells W, Jan LY, Jan YN. Tracing neurons with a kinesin-β-galactosidase fusion protein Roux's Archives of Developmental Biology. 202: 112-122. DOI: 10.1007/BF00636536  1
1988 Fischer JA, Giniger E, Maniatis T, Ptashne M. GAL4 activates transcription in Drosophila. Nature. 332: 853-6. PMID 3128741 DOI: 10.1038/332853a0  1
1988 Giniger E, Ptashne M. Cooperative DNA binding of the yeast transcriptional activator GAL4. Proceedings of the National Academy of Sciences of the United States of America. 85: 382-6. PMID 3124106  1
1987 Giniger E, Ptashne M. Transcription in yeast activated by a putative amphipathic alpha helix linked to a DNA binding unit. Nature. 330: 670-2. PMID 3317067 DOI: 10.1038/330670a0  1
1985 Giniger E, Varnum SM, Ptashne M. Specific DNA binding of GAL4, a positive regulatory protein of yeast. Cell. 40: 767-74. PMID 3886158 DOI: 10.1016/0092-8674(85)90336-8  1
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