| Year |
Citation |
Score |
| 2025 |
McGill Percy KC, Liu Z, Qi X. Mitochondrial dysfunction in Alzheimer's disease: Guiding the path to targeted therapies. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. e00525. PMID 39827052 DOI: 10.1016/j.neurot.2025.e00525 |
0.352 |
|
| 2024 |
Jishi A, Hu D, Shang Y, Wang R, Gunzler SA, Qi X. BCKDK loss impairs mitochondrial Complex I activity and drives alpha-synuclein aggregation in models of Parkinson's disease. Acta Neuropathologica Communications. 12: 198. PMID 39709505 DOI: 10.1186/s40478-024-01915-8 |
0.367 |
|
| 2024 |
Choi W, Fattah M, Shang Y, Thompson MP, Carrow KP, Hu D, Liu Z, Avram MJ, Bailey K, Berger O, Qi X, Gianneschi NC. Proteomimetic polymer blocks mitochondrial damage, rescues Huntington's neurons, and slows onset of neuropathology in vivo. Science Advances. 10: eado8307. PMID 39485846 DOI: 10.1126/sciadv.ado8307 |
0.348 |
|
| 2024 |
Sridharan PS, Koh Y, Miller E, Hu D, Chakraborty S, Tripathi SJ, Kee TR, Chaubey K, Vázquez-Rosa E, Barker S, Liu H, León-Alvarado RA, Franke K, Cintrón-Pérez CJ, Dhar M, ... ... Qi X, et al. Acutely blocking excessive mitochondrial fission prevents chronic neurodegeneration after traumatic brain injury. Cell Reports. Medicine. 101715. PMID 39241772 DOI: 10.1016/j.xcrm.2024.101715 |
0.351 |
|
| 2024 |
Ferreira JCB, Campos JC, Qvit N, Qi X, Bozi LHM, Bechara LRG, Lima VM, Queliconi BB, Disatnik MH, Dourado PMM, Kowaltowski AJ, Mochly-Rosen D. Author Correction: A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nature Communications. 15: 2889. PMID 38570501 DOI: 10.1038/s41467-024-47288-3 |
0.425 |
|
| 2021 |
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, Lundberg K, Adams DJ, Qi X. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nature Communications. 12: 5305. PMID 34489447 DOI: 10.1038/s41467-021-25651-y |
0.331 |
|
| 2021 |
Hu D, Liu Z, Qi X. UPR activation protects against MPP-induced toxicity in a cell culture model of Parkinson's disease. Biochemical and Biophysical Research Communications. 569: 17-22. PMID 34216993 DOI: 10.1016/j.bbrc.2021.06.079 |
0.31 |
|
| 2020 |
Hu D, Qi X. Quantifying Drp1-Mediated Mitochondrial Fission by Immunostaining in Fixed Cells. Methods in Molecular Biology (Clifton, N.J.). 2159: 197-204. PMID 32529373 DOI: 10.1007/978-1-0716-0676-6_15 |
0.393 |
|
| 2020 |
Hu D, Qi X. Measuring Drp1 Activity in Mitochondrial Fission In Vivo. Methods in Molecular Biology (Clifton, N.J.). 2159: 189-195. PMID 32529372 DOI: 10.1007/978-1-0716-0676-6_14 |
0.395 |
|
| 2019 |
Zhao Y, Sun X, Hu D, Prosdocimo DA, Hoppel C, Jain MK, Ramachandran R, Qi X. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nature Communications. 10: 1371. PMID 30914652 DOI: 10.1038/S41467-019-09291-X |
0.427 |
|
| 2019 |
Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, Hong Y, Ford C, Luo Y, Qi X. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathologica. PMID 30877431 DOI: 10.1007/S00401-019-01993-2 |
0.42 |
|
| 2019 |
Fu Z, Liu F, Liu C, Jin B, Jiang Y, Tang M, Qi X, Guo X. Mutant huntingtin inhibits the mitochondrial unfolded protein response by impairing ABCB10 mRNA stability. Biochimica Et Biophysica Acta. Molecular Basis of Disease. PMID 30802639 DOI: 10.1016/J.Bbadis.2019.02.015 |
0.44 |
|
| 2019 |
Ferreira JCB, Campos JC, Qvit N, Qi X, Bozi LHM, Bechara LRG, Lima VM, Queliconi BB, Disatnik MH, Dourado PMM, Kowaltowski AJ, Mochly-Rosen D. A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nature Communications. 10: 329. PMID 30659190 DOI: 10.1038/S41467-018-08276-6 |
0.603 |
|
| 2019 |
Lu B, Mahajan M, Mandal A, Bharambe N, Wang R, Wel Pvd, Buck M, Qi X, Ramachandran R. Structural and Mechanistic Bases of Drp1-Cardiolipin Interactions in Mitochondrial Fission Biophysical Journal. 116. DOI: 10.1016/J.Bpj.2018.11.2453 |
0.343 |
|
| 2018 |
Zhao Y, Sun X, Qi X. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease. Biochemical and Biophysical Research Communications. PMID 30449600 DOI: 10.1016/J.Bbrc.2018.11.031 |
0.376 |
|
| 2018 |
Yin Y, Qi X, Qiao Y, Liu H, Yan Z, Li H, Liu Z. The association of neuronal stress with activating transcription factor 3 in dorsal root ganglion of in vivo and in vitro models of bortezomib-induced neuropathy. Current Cancer Drug Targets. PMID 30289077 DOI: 10.2174/1568009618666181003170027 |
0.318 |
|
| 2018 |
Lu B, Kennedy B, Clinton RW, Wang EJ, McHugh D, Stepanyants N, Macdonald PJ, Mears JA, Qi X, Ramachandran R. Steric interference from intrinsically disordered regions controls dynamin-related protein 1 self-assembly during mitochondrial fission. Scientific Reports. 8: 10879. PMID 30022112 DOI: 10.1038/S41598-018-29001-9 |
0.324 |
|
| 2018 |
Roe AJ, Qi X. Drp1 phosphorylation by MAPK1 causes mitochondrial dysfunction in cell culture model of Huntington's disease. Biochemical and Biophysical Research Communications. PMID 29397067 DOI: 10.1016/J.Bbrc.2018.01.114 |
0.531 |
|
| 2017 |
Luo F, Herrup K, Qi X, Yang Y. Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis. Experimental Neurology. PMID 28238799 DOI: 10.1016/J.Expneurol.2017.02.015 |
0.417 |
|
| 2017 |
Qi X. eIF2α links mitochondrial dysfunction to dendritic degeneration. The Journal of Cell Biology. PMID 28209643 DOI: 10.1083/jcb.201701062 |
0.352 |
|
| 2016 |
Guo X, Qi X. VCP cooperates with UBXD1 to degrade mitochondrial outer membrane protein MCL1 in model of Huntington's disease. Biochimica Et Biophysica Acta. PMID 27913212 DOI: 10.1016/J.Bbadis.2016.11.026 |
0.414 |
|
| 2016 |
Disatnik MH, Joshi AU, Saw NL, Shamloo M, Leavitt BR, Qi X, Mochly-Rosen D. Potential biomarkers to follow the progression and treatment response of Huntington's disease. The Journal of Experimental Medicine. PMID 27821553 DOI: 10.1084/Jem.20160776 |
0.603 |
|
| 2016 |
Filichia E, Hoffer B, Qi X, Luo Y. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP. Scientific Reports. 6: 32656. PMID 27619562 DOI: 10.1038/Srep32656 |
0.416 |
|
| 2016 |
Guo X, Sun X, Hu D, Wang YJ, Fujioka H, Vyas R, Chakrapani S, Joshi AU, Luo Y, Mochly-Rosen D, Qi X. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nature Communications. 7: 12646. PMID 27561680 DOI: 10.1038/Ncomms12646 |
0.656 |
|
| 2016 |
Qi X, Davis B, Chiang YH, Filichia E, Barnett A, Greig NH, Hoffer B, Luo Y. Dopaminergic neuron-specific deletion of p53 gene is neuroprotective in an experimental Parkinson's disease model. Journal of Neurochemistry. PMID 27317935 DOI: 10.1111/Jnc.13706 |
0.303 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Qi X, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.303 |
|
| 2015 |
Clinton RW, Francy CA, Ramachandran R, Qi X, Mears JA. Dynamin-Related Protein 1 Oligomerization in Solution Impairs Functional Interactions with Membrane-Anchored Mitochondrial Fission Factor. The Journal of Biological Chemistry. PMID 26578514 DOI: 10.1074/Jbc.M115.680025 |
0.363 |
|
| 2015 |
Macdonald PJ, Francy CA, Stepanyants N, Lehman L, Baglio A, Mears JA, Qi X, Ramachandran R. Distinct Splice Variants of Dynamin-related Protein 1 Differentially Utilize Mitochondrial Fission Factor as an Effector of Cooperative GTPase Activity. The Journal of Biological Chemistry. PMID 26578513 DOI: 10.1074/Jbc.M115.680181 |
0.367 |
|
| 2015 |
Luo Y, Hoffer A, Hoffer B, Qi X. Mitochondria: A Therapeutic Target for Parkinson's Disease? International Journal of Molecular Sciences. 16: 20704-30. PMID 26340618 DOI: 10.3390/Ijms160920704 |
0.384 |
|
| 2015 |
Stepanyants N, Macdonald PJ, Francy CA, Mears JA, Qi X, Ramachandran R. Cardiolipin's propensity for phase transition and its reorganization by dynamin-related protein 1 form a basis for mitochondrial membrane fission. Molecular Biology of the Cell. PMID 26157169 DOI: 10.1091/Mbc.E15-06-0330 |
0.326 |
|
| 2015 |
Su YC, Guo X, Qi X. Threonine 56 phosphorylation of Bcl-2 is required for LRRK2 G2019S-induced mitochondrial depolarization and autophagy. Biochimica Et Biophysica Acta. 1852: 12-21. PMID 25446991 DOI: 10.1016/J.Bbadis.2014.11.009 |
0.362 |
|
| 2014 |
Mochly-Rosen D, Disatnik MH, Qi X. The challenge in translating basic research discoveries to treatment of Huntington disease. Rare Diseases (Austin, Tex.). 2: e28637. PMID 25054095 DOI: 10.4161/rdis.28637 |
0.436 |
|
| 2014 |
Macdonald PJ, Stepanyants N, Mehrotra N, Mears JA, Qi X, Sesaki H, Ramachandran R. A dimeric equilibrium intermediate nucleates Drp1 reassembly on mitochondrial membranes for fission. Molecular Biology of the Cell. 25: 1905-15. PMID 24790094 DOI: 10.1091/Mbc.E14-02-0728 |
0.36 |
|
| 2014 |
Guo X, Sesaki H, Qi X. Drp1 stabilizes p53 on the mitochondria to trigger necrosis under oxidative stress conditions in vitro and in vivo. The Biochemical Journal. 461: 137-46. PMID 24758576 DOI: 10.1042/Bj20131438 |
0.386 |
|
| 2013 |
Guo X, Disatnik MH, Monbureau M, Shamloo M, Mochly-Rosen D, Qi X. Inhibition of mitochondrial fragmentation diminishes Huntington's disease-associated neurodegeneration. The Journal of Clinical Investigation. 123: 5371-88. PMID 24231356 DOI: 10.1172/Jci70911 |
0.636 |
|
| 2013 |
Disatnik MH, Ferreira JC, Campos JC, Gomes KS, Dourado PM, Qi X, Mochly-Rosen D. Acute inhibition of excessive mitochondrial fission after myocardial infarction prevents long-term cardiac dysfunction. Journal of the American Heart Association. 2: e000461. PMID 24103571 DOI: 10.1161/Jaha.113.000461 |
0.551 |
|
| 2013 |
Su YC, Qi X. Inhibition of excessive mitochondrial fission reduced aberrant autophagy and neuronal damage caused by LRRK2 G2019S mutation. Human Molecular Genetics. 22: 4545-61. PMID 23813973 DOI: 10.1093/Hmg/Ddt301 |
0.389 |
|
| 2013 |
Qi X, Qvit N, Su YC, Mochly-Rosen D. A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity. Journal of Cell Science. 126: 789-802. PMID 23239023 DOI: 10.1242/Jcs.114439 |
0.624 |
|
| 2013 |
Su Y, Qi X. Impairment of mitochondrial dynamics: a target for the treatment of neurological disorders? Future Neurology. 8: 333-346. DOI: 10.2217/Fnl.13.8 |
0.411 |
|
| 2011 |
Qi X, Disatnik MH, Shen N, Sobel RA, Mochly-Rosen D. Aberrant mitochondrial fission in neurons induced by protein kinase C{delta} under oxidative stress conditions in vivo. Molecular Biology of the Cell. 22: 256-65. PMID 21119009 DOI: 10.1091/Mbc.E10-06-0551 |
0.623 |
|
| 2010 |
Palaniyandi SS, Qi X, Yogalingam G, Ferreira JC, Mochly-Rosen D. Regulation of mitochondrial processes: a target for heart failure. Drug Discovery Today. Disease Mechanisms. 7: e95-e102. PMID 21278905 DOI: 10.1016/J.Ddmec.2010.07.002 |
0.584 |
|
| 2008 |
Qi X, Mochly-Rosen D. The PKCdelta -Abl complex communicates ER stress to the mitochondria - an essential step in subsequent apoptosis. Journal of Cell Science. 121: 804-13. PMID 18285444 DOI: 10.1242/Jcs.024653 |
0.526 |
|
| 2008 |
Qi X, Inagaki K, Sobel RA, Mochly-Rosen D. Sustained pharmacological inhibition of deltaPKC protects against hypertensive encephalopathy through prevention of blood-brain barrier breakdown in rats. The Journal of Clinical Investigation. 118: 173-82. PMID 18097471 DOI: 10.1172/Jci32636 |
0.493 |
|
| 2007 |
Qi X, Vallentin A, Churchill E, Mochly-Rosen D. deltaPKC participates in the endoplasmic reticulum stress-induced response in cultured cardiac myocytes and ischemic heart. Journal of Molecular and Cellular Cardiology. 43: 420-8. PMID 17825316 DOI: 10.1016/J.Yjmcc.2007.07.061 |
0.519 |
|
| 2004 |
Qi X, Hosoi T, Okuma Y, Kaneko M, Nomura Y. Sodium 4-phenylbutyrate protects against cerebral ischemic injury. Molecular Pharmacology. 66: 899-908. PMID 15226415 DOI: 10.1124/Mol.104.001339 |
0.349 |
|
| 2004 |
Qi X, Okuma Y, Hosoi T, Nomura Y. Edaravone protects against hypoxia/ischemia-induced endoplasmic reticulum dysfunction. The Journal of Pharmacology and Experimental Therapeutics. 311: 388-93. PMID 15178695 DOI: 10.1124/Jpet.104.069088 |
0.326 |
|
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